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Prevalence of formaldehyde in indoor air of gross anatomy laboratory and cadaver storage room of a medical college 某医学院大体解剖实验室及尸库室内空气甲醛含量调查
Pub Date : 2014-01-01 DOI: 10.5455/JEOS.20140915115950
Shailesh Gahukar, U. Ramteke, D. Majumdar, Raman Malviya, Dinkar T Patil, J. Trivedi, C. Rao, Ashok H. Kale
Aim: Concentration of formaldehyde (FA) which is used to preserve cadavers for dissection in medical colleges was monitored in indoor air including at the breathing level in dissection classes during a 2-week study in a gross anatomy laboratory and also in the cadaver storage room in a Medical College in India in 2012. Materials and Methods: Air samples were collected for 30 min and 3 h to commensurate with World Health Organization (WHO) standard (short-term exposure limit) value of FA (30-min) and dissection class of 3 h duration respectively. Results: FA concentration ranged from 0.11 to 1.07 mg/m3 in the cadaver storage room and 0.06-1.12 mg/m3 in the gross anatomy laboratory. In samples taken at 5 ft height at the breathing level, FA concentration ranged from 0.32 to 0.86 mg/m3. Conclusions: Most of the observed FA levels were found to be above the prescribed FA guideline values laid down by organizations such as OSHA, ACGIH, WHO, Japan Ministry of Health, Labor, and Welfare and, therefore, could be considered as harmful for students’ and teachers’ health. FA concentrations reported from a few medical facilities in other countries are comparable, implying that some uniform management and control strategies for FA could be contemplated to reduce risks of FA exposure to students and teachers which are discussed in this paper.
目的:2012年,在印度一所医学院的大体解剖实验室和尸体储藏室进行了为期两周的研究,监测了室内空气中甲醛(FA)的浓度,包括解剖课上的呼吸水平。甲醛(FA)用于保存医学院校的解剖尸体。材料与方法:空气样本采集时间分别为30min和3h,与世界卫生组织(WHO)标准FA(短期暴露限值)值(30min)和解剖等级(3h)相符。结果:尸体储藏室FA浓度为0.11 ~ 1.07 mg/m3,大体解剖实验室FA浓度为0.06 ~ 1.12 mg/m3。在呼吸水平5英尺高度采集的样本中,FA浓度范围为0.32至0.86 mg/m3。结论:观察到的FA水平大多高于OSHA、ACGIH、WHO、日本厚生劳动省等组织制定的FA指导值,因此可以认为对学生和教师的健康有害。其他国家一些医疗机构报告的FA浓度具有可比性,这意味着可以考虑采用一些统一的FA管理和控制策略来降低学生和教师接触FA的风险,本文对此进行了讨论。
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引用次数: 9
The effect of lead toxicity on albino rats filiform and fungiform papillae and the possible protective role of honey and black seed 铅毒性对白化大鼠丝状和真菌状乳头的影响及蜂蜜和黑籽可能的保护作用
Pub Date : 2014-01-01 DOI: 10.5455/JEOS.20140328072527
Nehal El-Koshairy, R. Hassan, A. Halawa
Aims: (1) To investigate the histological changes in lingual papillae following lead toxicity in experimental rats. (2) To assess the possible protective effects of honey and black seed using light microscopy (LM) and scanning electron microscopy (SEM). Materials and Methods: Forty adult male albino rats were divided into four groups, 10 rats/group. Group I (control): 1 ml distilled water. Group II (lead): 16.5 mg lead acetate. Group III (honey + lead): 16.5 mg lead acetate + 50 mg/kg honey. Group IV (black seed + lead): 16.5 mg lead acetate + 50 mg/kg black seed aqueous suspension. All doses were given by oral intubation daily/6 weeks. After 6 weeks, rats were terminated, and tongues were decimated for LM and SEM. Results: True filiform papillae in Group II were distorted. Some appeared shorter while others had eroded tips and hyperkeratosis. Areas of epithelial erosion with complete loss of papillae and keratin were seen in some samples. Disfigured fungiform papillae with swollen taste buds were seen. In Group III, filiform and fungiform papillae appeared close to normal with minimal changes. However, in Group IV papillae were distorted with hyperkeratosis and limited areas of epithelial erosions were seen. Conclusion: The atrophy observed in Group II could be explained by lead-induced oxidative stress. Lead toxicity had a dual effect where increased free radical formation together with depletion of endogenous antioxidant enzymes resulted in inflammation and increased cell injury. Lead causes anemia and decreased salivary secretion, which may explain the epithelial erosion. Honey exerted its protective role through restoring enzymatic activity and through its antioxidant mechanism. Black seed offered lower protection than honey. Increased dose and/or duration of co-administration of black seed may improve protection.
目的:(1)观察实验性大鼠铅中毒后舌乳头的组织学变化。(2)利用光学显微镜(LM)和扫描电镜(SEM)评价蜂蜜和黑籽可能的保护作用。材料与方法:40只成年雄性白化大鼠分为4组,每组10只。第一组(对照组):蒸馏水1ml。第二组(铅):16.5毫克醋酸铅。第三组(蜂蜜+铅):16.5 mg醋酸铅+ 50 mg/kg蜂蜜。IV组(黑籽+铅):16.5 mg醋酸铅+ 50 mg/kg黑籽水溶液悬浮液。所有剂量均通过口服插管给予每日/6周。6周后,终止大鼠,割去大鼠舌头进行扫描电镜和扫描电镜观察。结果:II组真丝状乳头变形。有些人看起来更矮,而另一些人则有尖端侵蚀和角化过度。在一些样本中可见上皮侵蚀区,乳头和角蛋白完全消失。见真菌状乳头变形,味蕾肿胀。III组丝状和真菌状乳头接近正常,变化极小。然而,在IV组中,乳头扭曲,角化过度,可见有限区域的上皮糜烂。结论:II组大鼠脑萎缩可能与铅诱导的氧化应激有关。铅毒性具有双重作用,自由基形成增加和内源性抗氧化酶的消耗导致炎症和细胞损伤增加。铅导致贫血和唾液分泌减少,这可能解释了上皮侵蚀。蜂蜜通过恢复酶活性和抗氧化机制发挥保护作用。黑籽提供的保护不如蜂蜜。增加剂量和/或同时服用黑籽的时间可以提高保护作用。
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引用次数: 4
Occupational hazards exposure and their resultant effects on hospital attendants in health facilities of a local government area in South-South, Nigeria 职业危害暴露及其对尼日利亚南南地方政府地区卫生设施医护人员的影响
Pub Date : 2014-01-01 DOI: 10.5455/JEOS.20140521103409
J. Bamidele, O. Adeoye, M. Ntaji, E. Oladele
Background: Health attendants are constantly faced with the hazards inherent in their occupation. The objective of this study was to assess the occupational hazards exposures and their resultant effects on health attendants in health facilities in Warri South Local Government Area (LGA) of Delta state, Nigeria. Methods: This was a cross-sectional descriptive study of 199 health attendants selected from 37 hospitals within the LGA using Random Sampling Method. Data were collected by the interviewer and self-administered questionnaire and analyzed using the Statistical Package for the Social Sciences version 17 (SPSS Inc. Released 2008. SPSS Statistics for Windows, Version 17.0. Chicago: SPSS Inc.). Statistical analysis involved the use of the Chi square (ϗ2) and t-test among others as applicable. Statistical significance was set at P < 0.05 for all analyses. Results: Female workers accounted for 95.5% of the respondents; 98.0% had secondary level education and below. About 79.9% have not attended training courses on safety in the workplace. Many respondents (92.0%) believed that the occupation is hazardous. Among those that ever had injuries (26.6%), cuts and bruises accounted for (66.0%); followed closely by needle pricks (64.2%) and skin irritation/allergy (22.6%). Only 18.1% of the respondents had received hepatitis B vaccination. Only 50.8% and 10.1% respondents always wear hand gloves and protective boots, respectively. A significant association (P < 0.05) was found as those that have had training sustained fewer injuries than those who have not had training; also awareness about hazards is more among respondents with high educational status; those that have had training and those that have spent more years at work. Conclusion: Health attendants in this study are aware of the hazardous nature of their occupation, but still vulnerable to direct hazards exposure. We recommend that there should be mandatory standardized training and re-training of these hospital attendants on the potential hazards of their work and measures should be put in place to enforce the usage of personal protective equipment by this group of workers.
背景:卫生服务人员经常面临其职业所固有的危害。本研究的目的是评估职业危害暴露及其对尼日利亚三角洲州瓦里南地方政府区卫生机构卫生服务人员的影响。方法:采用横断面描述性研究,采用随机抽样方法,从LGA内的37家医院选出199名卫生服务人员。数据由访谈者和自我管理的问卷收集,并使用社会科学统计软件包17版(SPSS Inc.)进行分析。2008年发布的。SPSS Statistics for Windows, Version 17.0。芝加哥:SPSS Inc.)。统计分析包括使用卡方(ϗ2)和t检验等。所有分析均以P < 0.05为统计学意义。结果:女性职工占95.5%;98.0%的人受过中等及以下教育。约79.9%没有参加有关工作场所安全的培训课程。许多受访者(92.0%)认为该职业是危险的。曾经有过外伤的占26.6%,其中割伤和瘀伤占66.0%;其次是针刺(64.2%)和皮肤刺激/过敏(22.6%)。只有18.1%的受访者接种过乙肝疫苗。只有50.8%及10.1%的受访者会佩戴手套及防护靴。有训练的患者比没有训练的患者更少受伤,两者有显著的相关性(P < 0.05);此外,受教育程度高的受访者对危险的认识更高;一种是接受过培训的,另一种是工作多年的。结论:本研究中卫生服务人员意识到其职业的危险性,但仍然容易受到直接危害暴露。我们建议对这些医院工作人员进行强制性的标准化培训和再培训,使其了解其工作的潜在危险,并采取措施强制这群工人使用个人防护设备。
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引用次数: 6
Manifestation ,complications and clinical outcome in paraquat poison ? A hospital based study in a rural area of Karnataka - 百草枯中毒的表现、并发症和临床结局?在卡纳塔克邦农村地区进行的以医院为基础的研究
Pub Date : 2014-01-01 DOI: 10.5455/JEOS.20140127031530
T. Banday, S. Bhat, S. Bhat
Background; Paraquat is a broad spectrum liquid herbicide, leading to severe and often fatal toxicity. Most cases of intoxication, especially in third-world countries are due to suicidal attempts rather than homicidal or accidental exposure, because of its widespread availability and relative low cost. Diagnosis is often difficult in the absence of proper history, nonspecific clinical features, and lack of diagnostic tests. Objective; To describe the variability in presentation , primary outcome from intentional poisoning and to review its impact on morbidity and mortality of poisoning. Results; We report a case series of eight patients with paraquat poisoning who presented predominantly with pain in throat and vomiting .Out of eight cases six patients died despite intensive treatment. Most deaths occurred within in two weeks. Conclusion; Paraquat poison is highly lethal or deadly poison with very high mortality rate of around 70 to 80%.Also presentation may be variable and sometimes patient may present with mild symptoms with normal vitals or may remain asymptomatic for first few days. Although even in such cases morbidity and mortality of poison may be very high .
背景;百草枯是一种广谱液体除草剂,毒性严重,往往致命。大多数中毒病例,特别是在第三世界国家,是由于自杀企图,而不是杀人或意外接触,因为它的广泛可用性和相对较低的成本。在缺乏适当的病史、非特异性临床特征和缺乏诊断测试的情况下,诊断往往很困难。客观的;描述故意中毒的表现、主要结果的可变性,并回顾其对中毒发病率和死亡率的影响。结果;我们报告了8例百草枯中毒患者的病例系列,他们主要表现为喉咙疼痛和呕吐。在8例病例中,6例患者尽管经过强化治疗仍死亡。大多数死亡发生在两周内。结论;百草枯是一种高度致命或致命的毒药,死亡率非常高,约为70%至80%。此外,表现可能是可变的,有时患者可能表现出轻微的症状,生命体征正常,或可能在最初几天无症状。即使在这种情况下,中毒的发病率和死亡率也可能很高。
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引用次数: 7
Detection of Zoonotic Opportunistic Infections in HIV/AIDS Patients in Selected Residential Districts of Tigray Region, Ethiopia - 埃塞俄比亚提格雷地区部分居民区艾滋病毒/艾滋病患者人畜共患机会性感染的检测
Pub Date : 2014-01-01 DOI: 10.5455/JEOS.20131105124151
Sisay Weldegebriel Zeweld, D. Reta
Zoonotic opportunistic infections (OIs) are of the causes a major life-threatening condition in HIV/AIDS patients. In Ethiopia, OIs are the leading cause of death among people who have HIV. A cross-sectional study was carried out in Hewane, Korem and Alalmata districts from October 2012 to May 2013 to observe the occurrence of concurrent OIs such as tuberculosis, cryptosporidium, candidiasis and toxoplasmosis in HIV patients; to determine the association between possible risk factors and the human-animal interface responsible for development of OIs. Written informed consent was obtained from all participants and questionnaire was administered. A total of 651 HIV/AIDS patients and of which 300 (46.1%) were affected by OIs. Pregnancy (χ2 = 11.7; P = 0.0001), educational status (χ2 = 20.6; P = 0.0001), occupation (χ2 = 19.8; P = 0.001), raw milk consumption (χ2 = 32.14; P = 0.0001), raw meat consumption (χ2 = 16.82; P = 0.0001), regular contact with animals (χ2 = 7.83; P = 0.005) and the diabetic mellitus status (χ2 = 23.1; P =0.0001) were found to have significant statistical association with the detection of OIs in patients. In conclusion, OIs are of the causes a major life-threatening condition. Unrecognized, unknown and denied risk behaviors for OIs can pose major diagnostic and therapeutic challenges to clinicians in Ethiopia. In views of the above conclusion; recommendations were suggested for possible control and prevention measures of OIs. Awareness about OIs should be created to HIV patients. All HIV-infected persons at risk for infection with OIs must be carefully evaluated and, if indicated, administered therapy to prevent the progression of latent infection to active disease and avoid the complications associated with HIV-related OIs. All HIV-infected patients undergoing treatment for OIs should be evaluated for antiretroviral therapy.
人畜共患机会性感染(OIs)是导致艾滋病毒/艾滋病患者危及生命的主要原因之一。在埃塞俄比亚,oi是艾滋病毒感染者死亡的主要原因。2012年10月至2013年5月,在河湾、韩国和阿拉木木塔地区开展横断面研究,观察HIV患者并发结核、隐孢子虫、念珠菌病和弓形虫病等oi的发生情况;以确定可能的风险因素与导致OIs发生的人-动物界面之间的关系。获得所有参与者的书面知情同意,并进行问卷调查。共有651名艾滋病毒/艾滋病患者,其中300人(46.1%)受到OIs的影响。妊娠(χ2 = 11.7;P = 0.0001),教育程度(χ2 = 20.6;P = 0.0001),职业(χ2 = 19.8;P = 0.001),原料奶消费量(χ2 = 32.14;P = 0.0001),生肉消费量(χ2 = 16.82;P = 0.0001),经常接触动物(χ2 = 7.83;P = 0.005)、糖尿病状况(χ2 = 23.1;P =0.0001)与患者的OIs检出率有显著的统计学关联。综上所述,oi是危及生命的主要原因之一。未被识别、未知和否认的OIs风险行为对埃塞俄比亚的临床医生构成了重大的诊断和治疗挑战。鉴于上述结论;提出了可能的控制和预防措施。应该提高艾滋病患者对oi的认识。必须仔细评估所有有感染外源性疾病风险的艾滋病毒感染者,如果有症状,必须给予治疗,以防止潜伏感染发展为活动性疾病,并避免与艾滋病毒相关的外源性疾病相关的并发症。所有接受OIs治疗的艾滋病毒感染者都应接受抗逆转录病毒治疗评估。
{"title":"Detection of Zoonotic Opportunistic Infections in HIV/AIDS Patients in Selected Residential Districts of Tigray Region, Ethiopia -","authors":"Sisay Weldegebriel Zeweld, D. Reta","doi":"10.5455/JEOS.20131105124151","DOIUrl":"https://doi.org/10.5455/JEOS.20131105124151","url":null,"abstract":"Zoonotic opportunistic infections (OIs) are of the causes a major life-threatening condition in HIV/AIDS patients. In Ethiopia, OIs are the leading cause of death among people who have HIV. A cross-sectional study was carried out in Hewane, Korem and Alalmata districts from October 2012 to May 2013 to observe the occurrence of concurrent OIs such as tuberculosis, cryptosporidium, candidiasis and toxoplasmosis in HIV patients; to determine the association between possible risk factors and the human-animal interface responsible for development of OIs. Written informed consent was obtained from all participants and questionnaire was administered. A total of 651 HIV/AIDS patients and of which 300 (46.1%) were affected by OIs. Pregnancy (χ2 = 11.7; P = 0.0001), educational status (χ2 = 20.6; P = 0.0001), occupation (χ2 = 19.8; P = 0.001), raw milk consumption (χ2 = 32.14; P = 0.0001), raw meat consumption (χ2 = 16.82; P = 0.0001), regular contact with animals (χ2 = 7.83; P = 0.005) and the diabetic mellitus status (χ2 = 23.1; P =0.0001) were found to have significant statistical association with the detection of OIs in patients. In conclusion, OIs are of the causes a major life-threatening condition. Unrecognized, unknown and denied risk behaviors for OIs can pose major diagnostic and therapeutic challenges to clinicians in Ethiopia. In views of the above conclusion; recommendations were suggested for possible control and prevention measures of OIs. Awareness about OIs should be created to HIV patients. All HIV-infected persons at risk for infection with OIs must be carefully evaluated and, if indicated, administered therapy to prevent the progression of latent infection to active disease and avoid the complications associated with HIV-related OIs. All HIV-infected patients undergoing treatment for OIs should be evaluated for antiretroviral therapy.","PeriodicalId":16086,"journal":{"name":"Journal of Environmental and Occupational Science","volume":"72 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74263864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Ambient air’s volatile organic compounds and potential ozone formation in urban area, Bangkok, Thailand - 泰国曼谷市区环境空气中挥发性有机化合物和潜在臭氧形成
Pub Date : 2014-01-01 DOI: 10.5455/JEOS.20140903015449
Tanasorn Tunsaringkarn, T. Prueksasit, Daisy Morknoy, Saowanee Semathong, Anusorn Rungsiyothin, Kalaya Zapaung
Aims: The study were evaluated for the presence of the ambient air volatile organic compounds (VOCs) (benzene, toluene, ethylbenzene and xylene [BTEX] and carbonyl compounds [CCs]) at the university, roadside and residential areas in order to assess the applicability for prediction of ozone formation in ambient air of these in urban area, Bangkok, Thailand. Methods: The ambient air VOCs levels were evaluated by the gas chromatography/flame ionization detector for BTEX analysis and the high-performance liquid chromatography/UV-visible detector for CCs analysis. Results: The comparison of VOCs levels in those areas showed that the roadside area had the highest VOCs levels (of toluene and benzene levels), while the residential area had the lowest of benzene level. However, the benzene levels of all studied-areas were higher than ambient air quality standard. The contributions of hydrocarbons to local ozone formation potential were evaluated in terms of maximum incremental reactivity. Our results showed that the largest contributors to ozone production in Bangkok were toluene and formaldehyde (possibly from the emission of biofuel motor vehicle exhaustion). The roadside area also had the highest ozone formation potential. The aromatic hydrocarbon was the major contribution to anthropogenic emissions of VOCs. However, anthropogenic emissions and photochemistry are mainly transported VOCs to ozone formation. Conclusion: There was the highest VOCs level at roadside area and also was the largest amount of ozone level from chemical reactions. Therefore, it is a need for more research and the environmental protection policy because it may have serious health risk from these pollutants in these areas.
目的:本研究评估了泰国曼谷市区大学、路边和居民区的环境空气挥发性有机化合物(VOCs)(苯、甲苯、乙苯和二甲苯[BTEX]和羰基化合物[CCs])的存在情况,以评估这些化合物在预测环境空气中臭氧形成方面的适用性。方法:采用气相色谱/火焰电离检测器进行BTEX分析,高效液相色谱/紫外可见检测器进行CCs分析。结果:各区VOCs水平比较显示,路边区VOCs(甲苯和苯)含量最高,居民区VOCs含量最低;然而,所有研究区域的苯含量均高于环境空气质量标准。根据最大增量反应性评价了碳氢化合物对局部臭氧形成潜力的贡献。我们的研究结果表明,曼谷臭氧产生的最大贡献者是甲苯和甲醛(可能来自生物燃料机动车尾气的排放)。路边区域的臭氧形成潜力也最高。芳烃是VOCs人为排放的主要来源。然而,人为排放和光化学主要是将挥发性有机化合物输送到臭氧形成。结论:路边区VOCs含量最高,化学反应产生的臭氧量最大。因此,这些地区的污染物可能会对健康造成严重的危害,因此需要更多的研究和环保政策。
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引用次数: 18
Monitoring of metal contaminations in groundwater in Northern Rajasthan, India - 印度拉贾斯坦邦北部地下水金属污染监测
Pub Date : 2014-01-01 DOI: 10.5455/JEOS.20140223121124
V. Duggal, A. Rani, Rohit Mehra
Aim: The purpose of this study was to monitor concentrations of Zn, Cd, Pb, Cu and pH in groundwater of Hanumangarh, Sri Ganganagar, Churu and Sikar districts of in Northern Rajasthan, India; and to identify any relationships between metals. Materials and Methods: Heavy metals were analyzed by inductively coupled plasma mass spectrometry. Results: The measured concentrations of Zn, Cd, Pb and Cu varied from 14 to 23685 μg/l, 0.18 to 6.70 μg/l, 1 to 17 μg/l and 5 to 73 μg/l with overall mean values of 1595 ± 4094, 0.68 ± 1.02, 9 ± 4.44 and 23 ± 17 μg/l respectively. Conclusions: Copper level was found to be below the permissible limit of United States Environmental Protection Agency (1300 μg/l). In water sample code H-8 (Morjand Sikhan), the level of Cd was found (6.70 μg/l)to be above the permissible level (5 μg/l). In water samples codes H-7, H-9 and S-7 (Amarpura Jallu Khatt, Amar Singh Wala and Khandela-2), the level of Pb was found to be above the permissible level (15 μg/l). Significant correlations were found among the pH of water and different heavy metal concentrations.
目的:监测印度拉贾斯坦邦北部哈努曼加尔、斯里甘纳加尔、丘鲁和西卡尔地区地下水中锌、镉、铅、铜和pH的浓度;并确定金属之间的关系。材料与方法:用电感耦合等离子体质谱法分析重金属。结果:锌、镉、铅、铜的测定浓度分别为14 ~ 23685 μg/l、0.18 ~ 6.70 μg/l、1 ~ 17 μg/l和5 ~ 73 μg/l,总体平均值分别为1595±4094、0.68±1.02、9±4.44和23±17 μg/l。结论:检测到的铜含量低于美国环保局允许限量(1300 μg/l)。水样代码H-8 (Morjand Sikhan)的镉含量(6.70 μg/l)高于允许值(5 μg/l)。在水样编号H-7、H-9和S-7 (Amarpura Jallu Khatt、Amar Singh Wala和Khandela-2)中,铅含量高于允许值(15 μg/l)。水体pH值与不同重金属浓度呈显著相关。
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引用次数: 10
On the genetic effects of low-dose radiation - 关于低剂量辐射的遗传效应
Pub Date : 2014-01-01 DOI: 10.5455/JEOS.20140929042654
Sergei V. Jargin
There is a discrepancy between the reportedly significant elevation in a minisatellite DNA mutation rate in the children of parents, who had been exposed to radiation from the Chernobyl accident, and absence of significant inherited genetic effects found among the offspring of atomic bomb survivors. At the same time, average doses received by the residents of the contaminated areas, where the studies of the children of exposed parents were performed, had been comparable to those from the natural radiation background. Several publications exaggerating medical consequences of elevated radiation background were discussed earlier. The following flaws can be found in such papers: interpretation of spontaneous conditions as radiation-induced, indication of radioactivity or dose levels without confrontation with the natural radiation background, conclusions about incidence increase of certain conditions without an adequate comparison with a control. In conclusion, arguments in favor of inapplicability of the linear non-threshold theory to the radiation doses, comparable to those from the natural radiation background, are discussed here.
据报道,受到切尔诺贝利事故辐射的父母的子女的小卫星DNA突变率显著升高,但在原子弹幸存者的后代中没有发现显著的遗传基因影响,这两者之间存在差异。与此同时,受污染地区居民接受的平均剂量与自然辐射本底的剂量相当。受污染地区是对受辐射父母的子女进行研究的地方。前面讨论了一些夸大辐射本底升高的医疗后果的出版物。在这类论文中可以发现以下缺陷:将自发条件解释为辐射引起的,指示放射性或剂量水平而不与自然辐射本底相冲突,关于某些条件发生率增加的结论而没有与对照进行充分的比较。总之,本文讨论了支持线性非阈值理论不适用于与自然辐射本底辐射剂量相当的辐射剂量的论点。
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引用次数: 14
Volatile Organic Compounds Exposure and Health Risks among Street Venders in Urban Area, Bangkok 曼谷市区街头小贩的挥发性有机化合物暴露与健康风险
Pub Date : 2014-01-01 DOI: 10.5455/JEOS.20131219105033
Tanasorn Tunsaringkarn, T. Prueksasit, Soawanee Sematong, W. Siriwong, Navaporn Kanjanasiranont, Kalaya Zapuang, Daisy Morknoy, Anusorn Rungsiyothin
Air pollution has been for a long time a danger to human health and ecosystems. Many of the world's large cities today have bad air quality and can have a lot of health problems because of air pollution. Health risk of volatile organic compounds (VOCs: benzene, toluene, ethylbenzene and xylene (BTEX) and carbonyl compounds; CCs) exposures and their associations with non-specific symptoms of street venders at main roadsides were assessed in Pathumwan Area, central Bangkok, Thailand. A questionnaire was performed for characteristics and non-specific symptoms of street venders. Ambient air and personal air samples were collected at 5 sites of main roadsides and street venders for 8 h during work time. They were collected using 2,4 DNPH cartridge for carbonyl compounds (CCs) by HPLC/UV and activated charcoal tube for BTEX analyses by GC/FID. The results of this study showed that ambient air and personal air samples were not significant different. The life time cancer risk of street venders of benzene, ethylbenzene, formaldehyde and acetaldehyde exposures were 3.12E-06, 8.00E-08, 3.20E-06 and 6.02E-07 which total cancer risk was higher than acceptable limited. But hazard quoteint (HQ) ranges of benzene, xylene, formaldehyde, acetaldehyde and propionaldehyde exposures were lower than 1. The total cancer risk (7.00E-06) of these workers was higher than acceptable limited but hazard index (HI) was lower than limited value. The prevalence of headache, fatigue, dizziness and throat irritation symptoms of street venders were 58.0%, 47.8%, 26.5% and 24.6% respectively which most of them were associated with VOCs exposures.
长期以来,空气污染一直对人类健康和生态系统构成威胁。如今,世界上许多大城市的空气质量都很差,并且由于空气污染会产生很多健康问题。挥发性有机化合物(VOCs:苯、甲苯、乙苯和二甲苯(BTEX))和羰基化合物的健康风险;评估了泰国曼谷中部Pathumwan地区主要路边摊贩的CCs暴露及其与非特异性症状的关系。对街头小贩的特征和非特异性症状进行问卷调查。在工作时间内,在5个主要路旁及街市摊贩地点采集环境空气及个人空气样本8小时。采用高效液相色谱/紫外分光光度法(HPLC/UV)和活性炭管(GC/FID)对羰基化合物(CCs)进行BTEX分析。本研究结果表明,环境空气和个人空气样本没有显著差异。暴露于苯、乙苯、甲醛和乙醛的摊贩终生致癌风险分别为3.12E-06、8.00E-08、3.20E-06和6.020 e -07,总致癌风险高于可接受限度。但苯、二甲苯、甲醛、乙醛和丙醛暴露的危害指数(HQ)范围均小于1。这些工人的总癌症危险度(7.00E-06)高于可接受限度,但危害指数(HI)低于可接受限度。街头小贩出现头痛、疲劳、头晕和咽喉刺激症状的比例分别为58.0%、47.8%、26.5%和24.6%,其中大部分与VOCs暴露有关。
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引用次数: 6
National Register of Radiofrequency Workers: Exploring health eff ects of occupational radiofrequency radiation exposure - 国家射频工作人员注册:探索职业射频辐射暴露对健康的影响
Pub Date : 2014-01-01 DOI: 10.5455/JEOS.20140921104241
I. Litchfield
Background: Radiofrequency (RF) radiation continues to proliferate in the workplace. However, there is a broadly acknowledged need for additional research exploring the potential health effects of occupational exposure to RF. Aims: The aim was to establish a register of workers occupationally exposed to RF, in line with the recommendation of the Independent Expert Group on Mobile Phones. This database is to be used as a resource for the investigation of any potential health effects of RF exposure. Methods: Following a series of consultations with industry and other relevant organizations, the Health and Safety Executive (HSE) established a Steering Group in 2002 to manage the establishment of the National Register of individuals potentially exposed above public RF exposure guidelines. The Steering Group selected the University of Birmingham to administer the recruitment process. Recruitment and the first wave of analysis are due to finish in 2015. Results: The recruitment of a cohort of some 2500 individuals is near completion, and the initial study, a long-term follow-up of the cohort investigating mortality and cancer incidence is underway. Conclusions: The National Register of RF Workers provides the basis to explore potentially adverse health outcomes from occupational RF exposure. Funded by, key industry sponsors and supported by the University of Birmingham and HSE, the collaborative nature of the register provides an exemplar of how studies of occupational health can continue to be funded and managed.
背景:射频(RF)辐射在工作场所持续扩散。然而,人们普遍认为有必要进一步研究职业接触射频的潜在健康影响。目的:目的是根据移动电话问题独立专家组的建议,建立职业接触射频的工人登记册。该数据库将用作调查射频接触对健康的任何潜在影响的资源。方法:在与工业界和其他相关组织进行了一系列磋商后,健康与安全执行局(HSE)于2002年成立了一个指导小组,管理建立可能暴露于公共射频暴露指南以上的个人的国家登记册。指导小组选择了伯明翰大学来管理招聘过程。招聘和第一波分析工作将于2015年结束。结果:约2500人的队列招募接近完成,初步研究,对队列的长期随访调查死亡率和癌症发病率正在进行中。结论:国家射频工作人员登记册为探讨职业射频暴露的潜在不良健康后果提供了基础。由主要行业赞助商资助,并得到伯明翰大学和HSE的支持,该登记册的协作性质为如何继续资助和管理职业健康研究提供了一个范例。
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引用次数: 1
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Journal of Environmental and Occupational Science
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