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Utility of the ID-migraine tool in migraine without aura diagnosis: an experience from Nigeria id -偏头痛工具在无先兆偏头痛诊断中的应用:尼日利亚的经验
Pub Date : 2020-01-01 DOI: 10.5455/jmas.99966
Sidney K. Oparah, U. Asibong, E. Olose, Simon Ozomma
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引用次数: 0
Comparison on psychometric analysis for pathology course before and after the implementation of the multiple choice questions guidelines in a regional university, Kingdom of Saudi Arabia 沙特阿拉伯王国某地区大学病理学课程实施多项选择题指导前后的心理测量分析比较
Pub Date : 2020-01-01 DOI: 10.5455/jmas.86528
K. Salih, O. Elfaki, A. Amri, Mohamed Osman, M. Shraim
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引用次数: 0
Prevalence of tinnitus in hypertensive patients: In a clinical setup 高血压患者耳鸣的患病率:在临床设置
Pub Date : 2020-01-01 DOI: 10.5455/jmas.84563
Shahana Azmat, Nazia Mumtaz, G. Saqulain
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引用次数: 1
COVID-19: The significance to recognize initial ocular evidence and protective eyewear COVID-19:识别初始眼部证据和防护眼镜的意义
Pub Date : 2020-01-01 DOI: 10.5455/jmas.102882
Raj Kumar, Deepak Gupta
Emergence of novel corona virus (2019-nCOV) and evolving into a pandemic in a short span of time has caught the entire humanity unwarranted Most of the population effected had predominant respiratory presentation which in many cases worsened very soon leading to deaths The whole healthcare community was focused on the respiratory system and little did they know about non-respiratory symptoms until mild to moderate cases of COVID started to rise manifesting in various forms though predominantly most patients had lung involvement Important to mention are gastrointestinal symptoms without overt respiratory symptoms Isolated case reports mentioned diverse presentations including eye involvement We here give a brief account of eye involvement in COVID and precautionary measures for eye protection especially for eye care professionals
新型冠状病毒(2019-nCOV)的出现并在短时间内演变成大流行,使整个人类毫无理由地受到影响,大多数受影响的人群主要表现为呼吸道症状,在许多情况下,这种症状很快恶化导致死亡。整个医疗保健界都专注于呼吸系统,他们对非呼吸道症状知之甚少,直到轻度到中度的COVID病例开始上升,以各种形式表现出来,尽管主要是大多数患者有肺部受累,重要的是胃肠道症状,没有明显的呼吸道症状,孤立病例报告提到了多种表现,包括眼睛受累。我们在这里简要介绍COVID对眼睛的影响,以及眼睛保护的预防措施,特别是对眼睛护理专业人员
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引用次数: 0
Mucosal healing after high dose pantoprazole in acute corrosive injury of esophagus 大剂量泮托拉唑治疗食管急性腐蚀性损伤后粘膜愈合
Pub Date : 2020-01-01 DOI: 10.5455/JMAS.108114
R. Nanda, A. Mohammed
INTRODUCTION : The ingestion of corrosive agents is still an important public health issue in our country. The GIT injuries caused by caustic agents can range from minor to fatal, or can lead to chronic disease with poor quality of life. Corrosive agents with a pH level less than two or more than twelve can rapidly penetrate the layers of the oesophagus and result in necrosis and scar formation in the mucosa. Acidic agents produce coagulation necrosis and eschar formation that may limit tissue penetration and may even spare the oesophagus when the transit is rapid. On the other hand, Alkaline agents when ingested produce liquefaction necrosis and can cause serious oesophageal injury by penetrating to deep muscle layers. The basic histopathologic reaction of tissue subjected to caustic burn is the synthesis, deposition and remodelling of collagen. Following full-thickness injuries to the oesophageal wall, the normal oesophagus is replaced by dense connective tissue. Collagen overproduction has been estimated to cause stenosis in half of the patients suffering severe burns. Consequently, when treating caustic burn injuries, it is necessary to prevent stenosis by inhibiting collagen synthesis or changing the properties of the deposited collagen. The optimal management protocol in the treatment of severe caustic injury remains controversial. The main goal of medical treatment is to inhibit inflammatory reaction or stricture formation secondary to oesophageal burning. Stricture formation is thought to be overcome by suppressing fibroplasia and scarring. Many agents directed at wound healing and stricture prevention have been used in several experimental studies in past. Results of such treatment protocols including steroids, antibiotics, heparin, indomethacin, sucralfate, vitamin E, as well as total parenteral nutrition are all controversial in treatment of corrosive burns. Randomised control trials on the role of proton pump inhibitors in caustic injuries of GIT are lacking. A few experimental studies have investigated the relationship between proton pump inhibitors and corrosive burns and has shown that proton pump inhibitors can reduce inflammation in early phase of caustic injury. Proton pump inhibitors, by decreasing gastric acid secretion and thereby GER can prevent worsening of corrosive injury. In addition proton pump inhibitors has also been shown to have anti-inflammatory and antioxidant properties. A prospective study from turkey on 13 patients have showed that omeprazole can be used effectively in treatment of acute corrosive injury of esophagus. There are no studies from India which have attempted to assess the usefulness of proton pump inhibitors in treatment of acute corrosive injury of esophagus. This prompted us to study the usefulness of pantoprazole in the treatment of patients presenting with acute corrosive injury of the oesophagus. AIM OF THE STUDY : To study the efficacy of high dose pantoprazole in
导读:腐蚀性物质的摄入在我国仍然是一个重要的公共卫生问题。由腐蚀剂引起的胃肠道损伤从轻微到致命不等,或可导致慢性疾病,生活质量差。pH值小于2或大于12的腐蚀性物质可以迅速穿透食道层,导致粘膜坏死和瘢痕形成。酸性药剂会产生凝固性坏死和瘢痕形成,这可能会限制组织的渗透,甚至在快速通过时可能会避免食道。另一方面,摄入碱性物质会产生液化性坏死,并可穿透深层肌肉层,造成严重的食管损伤。烧灼组织的基本组织病理反应是胶原蛋白的合成、沉积和重塑。食管壁全层损伤后,正常食管被致密结缔组织所取代。据估计,半数严重烧伤患者的血管狭窄是由胶原蛋白过量引起的。因此,在治疗烧灼伤时,有必要通过抑制胶原合成或改变沉积胶原的性质来防止狭窄。严重烧灼伤的最佳治疗方案仍存在争议。医学治疗的主要目的是抑制炎症反应或继发于食管烧伤的狭窄形成。狭窄的形成被认为是通过抑制纤维增生和瘢痕形成来克服的。许多针对伤口愈合和预防狭窄的药物已经在过去的一些实验研究中使用。包括类固醇、抗生素、肝素、吲哚美辛、硫糖铝、维生素E以及全肠外营养在内的治疗方案对腐蚀性烧伤的治疗结果都存在争议。缺乏质子泵抑制剂在胃肠道腐蚀性损伤中的作用的随机对照试验。一些实验研究探讨了质子泵抑制剂与腐蚀性烧伤之间的关系,并表明质子泵抑制剂可以减轻腐蚀性损伤早期的炎症。质子泵抑制剂通过减少胃酸分泌,从而抑制胃液的腐蚀损伤。此外,质子泵抑制剂也被证明具有抗炎和抗氧化的特性。土耳其13例患者的前瞻性研究表明,奥美拉唑可有效治疗急性食管腐蚀性损伤。没有来自印度的研究试图评估质子泵抑制剂在治疗食管急性腐蚀性损伤中的有效性。这促使我们研究泮托拉唑治疗急性食道腐蚀性损伤的有效性。研究目的:探讨大剂量泮托拉唑对食管急性腐蚀性损伤后粘膜愈合的影响。结论:腐蚀性损伤的治疗存在争议,目前尚无明确的治疗方案。静脉注射质子泵抑制剂广泛用于治疗腐蚀性损伤,尽管缺乏证据。我们的研究表明,通过静脉注射质子泵抑制剂可以实现有效的粘膜愈合。虽然我们的研究中大多数患者为轻度损伤,但有27%的患者为2b和3a级损伤。当分析仅限于这些患者时,53%的患者表现出1级的改善,33.3%的患者表现出2级的改善,13.3%的患者没有表现出改善。由此可见,大剂量泮托拉唑对损伤程度较高的患者也有益,并可预防这些患者的晚期并发症。需要在较高程度食管损伤患者中进行更大规模的随机安慰剂对照试验,以确定大剂量泮托拉唑是否应成为急性食管腐蚀性损伤患者治疗的标准护理。
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引用次数: 0
Prevalence of rheumatoid factor and serum uric acid level in persons above 25 years in Calabar metropolis 卡拉巴尔市25岁以上人群类风湿因子及血清尿酸水平的调查
Pub Date : 2020-01-01 DOI: 10.5455/jmas.52393
H. Okeke, C. Usoro, A. Anyanwu
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引用次数: 0
Influence of body mass index on variables of brainstem evoked response audiometry in children aged 2-10 year with delayed development of speech attending Bankura Sammilani Medical College 体重指数对班库拉医学院2-10岁言语发育迟缓儿童脑干诱发反应听力学变量的影响
Pub Date : 2020-01-01 DOI: 10.5455/jmas.91264
Swasti Banerjee, Susanta Gorai, Writtika Chattaraj
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引用次数: 0
The effect of yoghurt and soyghurt treatment on the number of lactic acid bacteria in CKD patients undergoing hemodialysis 酸奶和大豆治疗对血液透析CKD患者乳酸菌数量的影响
Pub Date : 2020-01-01 DOI: 10.5455/jmas.89819
E. Guntiyastutik, S. Sugiarto, A. M. P. Nuhrawangsa
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引用次数: 1
To estimate the point prevalence of Rifampicin re-sistant tuberculosis in extra pulmonary tuberculosis patients' as detected by CBNAAT in a district hospital and to analyze the data using logistic regression mathematical model 目的:估计某地区医院CBNAAT检测的肺结核患者中利福平耐药结核病的点患病率,并采用logistic回归数学模型对数据进行分析
Pub Date : 2020-01-01 DOI: 10.5455/jmas.109776
S. Rajamani
The aim of this study was to estimate the point prevalence of Rifampicin resistant Mycobacteria causing tuberculosis of lymph node as detected by cartridge based nucleic acid amplification test (CBNAAT) and analyzed using logistic regression mathematical modeling. An observational cross-sectional study was carried out in the Department of Otorhinolaryngology from July 2019 to February 2020 in a tertiary healthcare setting. Rifampicin resistant Mycobacteria were identified; data tabulated and analyzed to find the point prevalence of Rifampicin resistant tuberculosis. A total of 37 patients who presented to the OPD were included in the study. Confirmation of the tuberculosis was done either by fine needle aspiration cytology (FNAC) or by direct biopsy. Demographic characteristics of the patients were analyzed. A logical regression mathematical model of Rifampicin resistance in the district was created. Correlation matrix was calculated using Jamovi software. of Rifampicin resistance was dependent variable in logistic regression modeling. Levels VA and VB, posterior triangle group lymph nodes were most commonly involved. It was found that there is high prevalence 89.189% (p<0.01) of Rifampicin resistant Mycobacteria. Rifampicin resistance a 2.9672 greater odds per stage higher chance p=0.0291) treatment failure as compared to Rifampicin sensitive patients. Females have higher risk of harbouring Rifampicin Resistant Mycobacteria than males.
本研究的目的是估计基于核酸扩增试验(CBNAAT)检测的淋巴结结核分枝杆菌耐利福平点流行率,并采用logistic回归数学模型进行分析。2019年7月至2020年2月,在三级医疗机构的耳鼻喉科进行了一项观察性横断面研究。鉴定出耐利福平分枝杆菌;对数据进行制表和分析,以找出利福平耐药结核的点患病率。共有37名到OPD就诊的患者被纳入研究。通过细针抽吸细胞学(FNAC)或直接活检确认结核。分析患者的人口学特征。建立了该地区利福平耐药的逻辑回归数学模型。使用Jamovi软件计算相关矩阵。在logistic回归模型中,利福平耐药性为因变量。VA、VB水平,后三角组淋巴结最常受累。结果发现,耐利福平分枝杆菌的感染率较高,达89.189% (p<0.01)。与利福平敏感患者相比,利福平耐药患者每期治疗失败的几率(p=0.0291)高2.9672。女性携带利福平耐药分枝杆菌的风险高于男性。
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引用次数: 0
Dietary supplement intake and associated awareness among athletes in a university community in Sri Lanka 膳食补充剂的摄入和相关意识的运动员在一个大学社区在斯里兰卡
Pub Date : 2020-01-01 DOI: 10.5455/jmas.73671
N. Samarathunga, B. Weerakoon
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引用次数: 1
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Journal of Medical and Allied Sciences
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