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On saline infusion, clonus, molecules and forgotten scientists: Who was Dr Julius Sander (1840-1909)? 关于生理盐水输注、克隆症、分子和被遗忘的科学家:谁是朱利叶斯-桑德尔博士(1840-1909)?
IF 0.2 4区 哲学 Q3 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-02-01 Epub Date: 2021-12-16 DOI: 10.1177/09677720211065357
Georg A Petroianu

Zitterbewegungen des Fusses bei Dorsalflexion (shaking movements of the foot upon dorsal flexion) were observed independently from each other and described in the same issue of a German peer reviewed journal by Carl Westphal (1833-1890) at the Charité in Berlin and by Wilhelm Erb (1840-1921) in Heidelberg. While Westphal used the term Fussphaenomen, Erb is credited with coining the term clonus for the phenomenon. Both scientists are immortalized by various eponyms acknowledging their respective contributions to science. Little is known however about Julius Sander (1840-1909), in those days resident at Charité, who noticed the phenomenon and presented it to his superiors, Wilhelm Griesinger (1817 -1868) and Westphal. In addition to such observations, Sander made original contributions in resuscitation physiology while working with Hugo Kronecker (1839-1914). With Kronecker, Sander published observations on life saving transfusions with inorganic salt solutions in dogs "Bemerkung über lebensrettende Transfusion mit anorganischer Salzlösung bei Hunden" a very early work on isovolemic fluid resuscitation. The purpose of this communication is to highlight Sander's scientific contributions and to shed some light on his life, of which a German Lexicon stated that after 1870 no information on him can be ascertained anymore.

柏林夏里特医院的卡尔-韦斯特法尔(1833-1890 年)和海德堡的威廉-埃尔伯(1840-1921 年)在同一期德国同行评审期刊上分别独立地观察到了足背屈时的抖动(Zitterbewegungen des Fusses bei Dorsalflexion)。韦斯特法尔使用了 "Fussphaenomen "一词,而埃尔伯则为这一现象创造了 "clonus "一词。这两位科学家都有各种不朽的地名,以表彰他们各自对科学的贡献。然而,人们对朱利叶斯-桑德(Julius Sander,1840-1909 年)却知之甚少,他当时居住在夏里特,注意到了这一现象,并将其提交给了他的上司威廉-格里辛格(Wilhelm Griesinger,1817-1868 年)和韦斯特法尔。除了这些观察之外,桑德尔还与雨果-克罗内克(1839-1914 年)合作,在复苏生理学方面做出了原创性贡献。桑德与克罗内克尔一起发表了关于用无机盐溶液为狗输血救命的观察文章《Bemerkung über lebensrettende Transfusion mit anorganischer Salzlösung bei Hunden》,这是关于等容液体复苏的早期著作。这篇通讯的目的是突出桑德的科学贡献,并对他的生平作一些介绍。德文词典称,1870 年后,关于他的信息已无从查起。
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引用次数: 0
Granville Coggs (1925-2019) - WWII pilot, pioneering radiologist, and inspiration to minorities in medicine. 格兰维尔-科格斯(Granville Coggs,1925-2019 年)--二战飞行员、放射科先驱、医学界少数群体的启蒙者。
IF 0.2 4区 哲学 Q3 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-02-01 Epub Date: 2021-11-22 DOI: 10.1177/09677720211058314
Anish Karlapudi, Richard B Gunderman

Role models play an important role in firing the imagination of medical students and residents, and when it comes to attracting and sustaining under-represented minorities in fields such as medicine, the inspiring stories of minority physicians can make an especially important contribution. One such physician was Granville Coggs, an Arkansas native who overcame a stutter, served among the Tuskegee Airmen during World War II, graduated from Harvard Medical School, became the first black physician at Kaiser Hospital, established the San Antonio Breast Evaluation Center, and won gold medals as a senior track star.

榜样在激发医学生和住院医师的想象力方面发挥着重要作用,而在吸引和留住医学等领域代表性不足的少数族裔方面,少数族裔医生的励志故事可以做出特别重要的贡献。格兰维尔-科格斯(Granville Coggs)就是这样一位医生,他是阿肯色州人,曾克服口吃,在二战期间服役于塔斯基吉空军部队,毕业于哈佛大学医学院,成为凯泽医院的第一位黑人医生,建立了圣安东尼奥乳房评估中心,并作为资深田径明星获得过金牌。
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引用次数: 0
Franz Tappeiner (1816-1902): The physician who became headhunter. Portrait of a leading figure in 19th Century anthropology. 弗朗茨-塔佩纳(Franz Tappeiner,1816-1902 年):成为猎头人的医生。19 世纪人类学领军人物的肖像。
IF 0.2 4区 哲学 Q3 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-02-01 Epub Date: 2021-12-15 DOI: 10.1177/09677720211065356
Francesco Brigo, Mariano Martini

Franz Tappeiner (1816, Laas - 1902, Merano) was an Austrian physician and anthropologist. He studied at the universities of Prague, Padua and Vienna and in 1846 he moved to Merano. Tappeiner investigated the transmission of pulmonary tuberculosis in animal models and he dealt with public health. As an anatomist, he performed thousands of craniometrics measurements, creating a huge skull collection later donated to the Natural History Museum in Vienna. In 1878, Tappeiner turned to archeology and palaeoanthropology, with the aim of clarifying the origins of the Alpine population of Tyroleans. He was also active as a botanist.

弗朗茨-塔佩纳(1816-1902,梅拉诺)是奥地利医生和人类学家。他曾在布拉格、帕多瓦和维也纳的大学学习,1846 年移居梅拉诺。塔佩纳研究了肺结核在动物模型中的传播,并从事公共卫生工作。作为一名解剖学家,他进行了数以千计的头颅测量,收集了大量头骨,后来捐赠给了维也纳自然历史博物馆。1878 年,塔佩纳转向考古学和古人类学研究,目的是弄清蒂罗尔阿尔卑斯山居民的起源。他还是一位活跃的植物学家。
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引用次数: 0
A biography of Dr Carl Bodon: Pioneer of intracardiac injection of adrenaline. 卡尔-博登博士传记:心内注射肾上腺素的先驱。
IF 0.2 4区 哲学 Q3 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-02-01 Epub Date: 2021-11-22 DOI: 10.1177/09677720211058313
Jean Bodon, Theresa C Bodon, Christine M Ball, Eva J Bodon

This biographical essay will provide historical insights about Dr Carl Bodon who performed one of the first successful intracardiac injections of adrenaline to a patient and made important contributions to the understanding of cardiac diseases and women's health. Dr Bodon's biography reveals the story of a medical doctor who lived during tumultuous times between two world wars and ultimately died in the Holocaust. His story sheds light on forgotten contributors to the medical field and its practices.

这篇传记文章将提供有关卡尔-博登博士的历史性见解,他首次成功地为病人进行了心内注射肾上腺素,并为人们了解心脏疾病和妇女健康做出了重要贡献。博登博士的传记揭示了一位生活在两次世界大战之间动荡时期并最终死于大屠杀的医生的故事。他的故事揭示了被遗忘的医学领域及其实践的贡献者。
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引用次数: 0
William Warwick James OBE FRCS MCh FDS FLS (1874 to 1965). William Warwick James OBE FRCS MCh FDS FLS(1874 年至 1965 年)。
IF 0.2 4区 哲学 Q3 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-02-01 Epub Date: 2021-12-14 DOI: 10.1177/09677720211064295
Stanley Gelbier

William Warwick James was one of the most inspiring and outstanding dental surgeons of his time, a key researcher in dentistry and zoology and a pioneer in maxillofacial surgery. Most maxillofacial departments hold sets of his dental elevators. He wrote a major wartime work with Benjamin Fickling on the treatment of jaw and facial injuries.

威廉-沃里克-詹姆斯(William Warwick James)是那个时代最具启发性的杰出牙科医生之一,也是牙科和动物学的重要研究者和颌面外科的先驱。大多数颌面部科室都有他的牙科升降机。他与本杰明-菲克林(Benjamin Fickling)共同撰写了一部关于颌面部损伤治疗的重要战时著作。
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引用次数: 0
Salomón Hakim, MD (1922-2011): A honeymoon with Neurosurgery. 萨洛蒙-哈基姆,医学博士(1922-2011 年):与神经外科的蜜月。
IF 0.2 4区 哲学 Q3 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-02-01 Epub Date: 2021-10-29 DOI: 10.1177/09677720211054025
Daniel Jaramillo-Velásquez, Fernando Hakim, Andreas K Demetriades

Salomón Hakim (1922-2011) was a Colombian neurosurgeon and brain scientist This biography examines the social and cultural background through which he emerged as an inquisitive and multi-dimensional surgeon-scientist, and his lifelong contributions to the specialty of neurosurgery. With empirical knowledge in applied medical physics, electronics, electricity and chemistry, he understood the paradoxical phenomenon of symptomatic hydrocephalus with normal cerebrospinal fluid pressure. This ultimately led Hakim to describe in exquisite detail the physics of the cranial cavity and brain hydrodynamics. His name is intertwined with the identification of the entity of a syndrome which had not previously been addressed in the medical literature: Normal Pressure Hydrocephalus (Hakim's syndrome). Additionally, he designed and built various models of valved shunting devices to treat the condition (eg the Hakim programmable valve). Through his selflessness and cogent work, Hakim left a legacy and intellectual heritage that has allowed many colleagues worldwide to save thousands of lives who would be otherwise condemned to oblivion.

萨洛蒙-哈基姆(Salomón Hakim,1922-2011 年)是哥伦比亚的一名神经外科医生和脑科学家。这本传记研究了他作为一名好奇、多维的外科医生-科学家所经历的社会和文化背景,以及他毕生对神经外科专业的贡献。凭借在应用医学物理学、电子学、电学和化学方面的经验知识,他理解了有症状的脑积水与正常脑脊液压力之间的矛盾现象。这最终促使哈基姆详细描述了颅腔物理学和脑流体力学。他的名字与医学文献中从未涉及的一种综合征的实体鉴定交织在一起:正常压力脑积水(哈基姆综合征)。此外,他还设计并制造了各种型号的瓣膜分流装置来治疗这种疾病(如哈基姆可编程瓣膜)。哈基姆以其无私奉献的精神和令人信服的工作,为世界上许多同行留下了宝贵的财富和知识遗产,挽救了成千上万人的生命,否则这些人将被遗忘。
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引用次数: 0
Gladys Mary Wauchope (1889-1966): Brighton physician and second female medical student at the London Hospital Medical College. 格拉迪斯-玛丽-沃乔普(1889-1966 年):布莱顿医生,伦敦医院医学院第二位女医科学生。
IF 0.2 4区 哲学 Q3 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-02-01 Epub Date: 2021-06-14 DOI: 10.1177/09677720211023502
Elizabeth J Dickenson, Benjamin Whiston, Maxwell J Cooper

Gladys Mary Wauchope was a pioneering woman physician and general practitioner in London and Brighton. Descended from an ancient Scottish family, she was the second female medical student at the London Hospital Medical College after Elizabeth Garrett Anderson, enrolling during the brief period from 1918 to 1928 in which women were permitted to study medicine in mainstream London medical schools due to shortages of doctors caused by the First World War. Unperturbed by opposition to her gender from male colleagues, she was initially house physician on the firm of Sir Robert Hutchison at 'the London', and went on to hold an array of posts in large London hospitals at a time when finding such work was challenging for women doctors. She settled in Hove as a general practitioner in 1924, later becoming a consultant physician at several major Brighton hospitals. Made only the eighth female fellow of the Royal College of Physicians, she also set up the first diabetic clinic in Sussex and Kent. Gladys authored several books, including her autobiography 'The Story of a Woman Physician', which documents life through two world wars and the introduction of the National Health Service, whilst keenly observing the changing landscape of medicine and its place in society.

格拉迪斯-玛丽-沃乔普(Gladys Mary Wauchope)是伦敦和布莱顿的一位开创性女医师和全科医生。她出身于一个古老的苏格兰家庭,是继伊丽莎白-加勒特-安德森(Elizabeth Garrett Anderson)之后伦敦医院医学院的第二位女医科学生,入学时正值 1918 年至 1928 年的短暂时期,由于第一次世界大战导致医生短缺,伦敦主流医学院允许女性学习医学。她没有被男同事对其性别的反对所影响,最初在 "伦敦 "罗伯特-哈奇森爵士的公司担任内科医师,后来在伦敦的大型医院担任了一系列职位,而当时女医生要找到这样的工作是很困难的。1924 年,她以全科医生的身份在霍夫定居,后来成为布莱顿几家大医院的顾问医生。她是英国皇家内科医学院第八位女院士,还在苏塞克斯和肯特郡建立了第一家糖尿病诊所。格拉迪斯撰写了多部著作,其中包括她的自传《一个女医生的故事》,该书记录了她经历两次世界大战和推行国民健康服务的生活,同时敏锐地观察到了医学及其在社会中地位的变化。
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引用次数: 0
The contribution of the Scottish doctor Robert Erskine to the development of Russian medicine in the 18th century. 苏格兰医生罗伯特-厄斯金对 18 世纪俄罗斯医学发展的贡献。
IF 0.2 4区 哲学 Q3 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-02-01 Epub Date: 2021-12-27 DOI: 10.1177/09677720211053243
Dmitry Iskhakovich Mustafin, Maria Dmitrievna Sanatko, Iain Orr McDonald, Clive Wright

The Scottish doctor Robert Erskine (1677-1718) became Chief Doctor of Russia and personal physician to Tsar Peter the Great. Extensive archival material documents his remarkable career. From schooling in the village of Alva and apprenticeship to an Edinburgh apothecary, he went on to study medicine in Paris and Utrecht and was admitted to the Royal Society in London. Recruited into the service of the Tsar, to whom he became a trusted friend and counsellor, Erskine played a central role in the modernisation of Russian medicine, pharmacy and natural science in the early 18th century. His untimely death at age 41 was marked with a state funeral in St Petersburg. Some historians in Russia assert that in their country, the development of medicine and the natural sciences took place without the transitional stages of iatrochemistry and iatrophysics which characterised the shift in scientific thinking throughout Europe in the early modern period. This study of archival records shows that Erskine held iatrophysical and iatrochemical views in common with his European contemporaries. His influence ensured that Russia was thoroughly involved in European developments in science and medicine in the 18th century.

苏格兰医生罗伯特-厄斯金(1677-1718 年)成为俄罗斯的首席医生和沙皇彼得大帝的私人医生。大量档案资料记录了他非凡的职业生涯。从阿尔瓦村的学校和爱丁堡药剂师的学徒开始,他在巴黎和乌得勒支学习医学,并被伦敦皇家学会录取。18 世纪初,厄斯金受聘为沙皇服务,成为沙皇信赖的朋友和顾问,在俄罗斯医学、药学和自然科学的现代化进程中发挥了核心作用。他 41 岁时英年早逝,在圣彼得堡举行了国葬。俄罗斯的一些历史学家断言,在俄罗斯,医学和自然科学的发展没有经历近代早期欧洲科学思想转变的过渡阶段--即 "原子化学 "和 "原子物理学"。对档案记录的研究表明,厄斯金与他同时代的欧洲人一样,持有原子物理学和原子化学的观点。他的影响确保了俄罗斯在 18 世纪全面参与欧洲科学和医学的发展。
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引用次数: 0
Hematologist Bracha Ramot (1927-2006): Between the bedside and the bench. 血液学家布拉查-拉莫特(Bracha Ramot,1927-2006 年):在床边和工作台之间
IF 0.2 4区 哲学 Q3 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-02-01 Epub Date: 2022-12-23 DOI: 10.1177/09677720221140083
Laura Veronica Grunseid, Nurit Kirsh

The Hebrew University of Jerusalem opened the first medical school in Israel in May 1949. One of the select 45 students of its first class was Bracha (Chweidan) Ramot. After completing her medical studies with distinction, she went on to specialize in internal medicine and hematology and soon became a central figure in the development of hematology in Israel. In 1958, Ramot established the Hematological Institute at Tel-Hashomer hospital and served as its director until 1991. She devoted much of her time and effort to researching environmental and genetic factors that influence hematological conditions: deficiencies in coagulation factors, glucose metabolism disorders, and especially leukemias and lymphomas, including the type known as Hodgkin's disease. In 2001, Ramot, "The Doyenne of Israeli Hematology" as she was called in publications of the Albert Einstein Institute, was awarded the Israel Prize in Medical Sciences, the country's most prestigious prize. Her biography personifies the ability to overcome obstacles and challenges in one's personal life while concurrently becoming an exceedingly successful physician and researcher of extraordinary achievement.

1949 年 5 月,耶路撒冷希伯来大学开办了以色列第一所医学院。布拉查-拉莫特(Bracha (Chweidan) Ramot)是首届精选的 45 名学生之一。以优异的成绩完成医学学业后,她继续专攻内科和血液学,并很快成为以色列血液学发展的核心人物。1958 年,拉莫特在特尔哈霍姆医院建立了血液学研究所,并担任所长直至 1991 年。她将大量时间和精力用于研究影响血液病的环境和遗传因素:凝血因子缺陷、葡萄糖代谢紊乱,尤其是白血病和淋巴瘤,包括被称为霍奇金病的类型。2001 年,被阿尔伯特-爱因斯坦研究所出版物誉为 "以色列血液学女神 "的拉莫特荣获以色列医学科学奖,这是以色列最负盛名的奖项。她的传记充分体现了一个人在克服个人生活中的障碍和挑战的同时,还能成为一名非常成功的医生和取得非凡成就的研究人员的能力。
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引用次数: 0
Robert Lawson Tait (1845-1899): The true innovator of aseptic surgery? 罗伯特-劳森-泰特(1845-1899 年):无菌手术的真正创新者?
IF 0.2 4区 哲学 Q3 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-02-01 Epub Date: 2022-12-19 DOI: 10.1177/09677720221140085
Iain Macintyre, Sean Hughes

Robert Lawson Tait was an original thinker, a surgical innovator, a controversialist and an iconoclast. He made important contributions to surgery, was an eloquent supporter of Darwinian evolution and women in medicine and opposed vivisection. He is probably best remembered for his high-profile opposition to Listerian antisepsis which continued until his death. While Lister went on to receive the country's highest honours and was lauded throughout the world, Tait received much more modest honours and little subsequent recognition by historians. Yet it could be argued that Tait's system rather than Lister's was the basis of modern aseptic surgery. Tait never changed his views on asepsis over his lifetime and relied on surgical cleanliness, which, combined with his extensive clinical experience, enabled him to achieve outcomes as good or better than with antisepsis. By contrast, Listerism evolved over 30 years, claimed to be based on laboratory data and adopted the new discoveries of the germ theory of disease as they emerged. We compare the systems of Tait and Lister, explore the basis of Tait's opposition to Listerian methods and conclude that Tait's thinking underlies modern surgical practice and that he should receive greater acknowledgement for his contribution to the prevention of surgical infections.

罗伯特-劳森-泰特(Robert Lawson Tait)是一位具有独创性的思想家、外科创新者、争议家和偶像破坏者。他对外科手术做出了重要贡献,是达尔文进化论和医学界女性的有力支持者,并反对活体解剖。人们对他印象最深的可能是他高调反对李斯特防腐法,这种反对一直持续到他去世。李斯特后来获得了国家的最高荣誉,并受到全世界的赞誉,而泰特获得的荣誉要少得多,后来也很少得到历史学家的认可。但可以说,泰特而非李斯特的系统是现代无菌外科的基础。泰特终其一生都没有改变过他对无菌的看法,他依靠手术的清洁度,再加上他丰富的临床经验,使他取得了与防腐一样好甚至更好的效果。相比之下,李斯特主义历经 30 多年的发展,声称以实验室数据为基础,并采纳了疾病病菌理论的新发现。我们比较了泰特和李斯特的体系,探讨了泰特反对李斯特方法的依据,并得出结论:泰特的思想是现代外科实践的基础,他在预防外科感染方面的贡献应该得到更多的认可。
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引用次数: 0
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Journal of Medical Biography
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