Electroanalysis最新文献

This study endeavors to assess the impedance responses exhibited by 18650 Graphite||LiCoO₂ (C₆||LCO) cells under conditions of over-discharge and overcharge. The impedance measurements are conducted at a potential of 4.20 V, followed by subjecting the cells to over-discharge and overcharge scenarios. It is observed that the impedance magnitude experiences augmentation in both instances. Upon reaching a potential of 2.70 V, the electrochemical attributes of the cells revert to their normal state post over-discharge. However, the impedance characteristics persist even upon exceeding a potential of 4.70 V. These observations imply that overcharge induces enduring alterations in impedance behavior, while over-discharge is a reversible phenomenon. To delve deeper into the underlying mechanisms, an equivalent circuit process model is constructed. This model elucidates that over-discharge of Li-ion batteries is reversible, indicating the potential for restoration of original impedance behavior upon recharge. Conversely, overcharge precipitates permanent alterations in impedance behavior, engendering irreversible changes in battery characteristics. In summation, this study underscores the criticality of meticulously managing the charging and discharging processes of Li-ion batteries to avert irreversible impairment to impedance behavior, thereby safeguarding battery performance and longevity.

Green analytical methods are important techniques that aim to reduce or eliminate the use of harmful chemicals and waste in various analyses. These methods, based on green chemistry principles, are environmentally friendly and reliable. Electrochemical techniques have an essential role in diverse analyses, and are presented as a superior alternative to existing analytical devices in terms of different parameters. In the present review, we have comprehensively covered electrochemistry-based sensors that are developed using green chemistry principles and evaluated their performance characteristics and specific working conditions. We here included sensors developed based on potentiometry and voltammetry methodologies, and detailed their greenness potentials based on certain metrics. Considering the advantages provided by these environmentally friendly new generation sensors, it will be inevitable for researchers working in this field to direct their attention to sensors that can be produced with green approaches.

Antibiotic resistance is a crisis that is escalating nowadays. Thus, therapeutic drug monitoring (TDM) is crucial to personalize the dose. Point-of-care (POC) devices are very effective in TDM where drug concentration can be easily and continuously monitored. This work describes for the first time the use of inexpensive, transportable, efficacious, and eco-friendly POC solid-state potentiometric sensor for the TDM of Flucloxacillin (FLU) in spiked plasma samples. This was achieved by using an innovative glassy carbon electrode modified with ion sensing membrane doped with carbon nanotubes. Optimization of the sensing membrane composition was performed using different plasticizers and by adding an ionophore. This was followed by doping the ion sensing membrane with carbon nanotubes which resulted in enhancing the sensor's sensitivity towards FLU. Over a concentration range from 1.0×10⁻⁵–1.0×10⁻² M FLU, a linear response was obtained with a slope of 56.6 mV/decade. Our proposed sensor has been validated according to IUPAC recommendations with acceptable results.

It was effectively employed for a selective determination of FLU in the presence of a co-formulated antibiotic (Amoxicillin), along with other excipients in the dosage form, and in spiked plasma samples, without any interference. The whiteness of the method was assessed, which proves the high greenness and superb functionality of our proposed method.