Despite increasing rates for suicidal ideation in university students, male students remain reluctant in reporting such thoughts. It is thus paramount to establish more easily detectable risk factors for male students. The present study examines study dropout thoughts as potential low-treshold risk factor as well as gender-differences in established risk patterns. A total of N = 4894 German university students (24.6% men) completed a cross-sectional online survey on their mental health at the University of Cologne. In addition to sociodemographic and questions related to university studies (e.g., dropping out of studies), the Patient Health Questionnaire D (PHQ-D) was used to assess psychological syndromes (any psychological syndrome, depressive syndrome, alcohol syndrome), life stressors and suicidal ideation. Study dropout thoughts were more prevalent among male students, while being associated with increased suicidal ideation for both genders assessed. For all outcomes, significant gender-differences were observed with financial stress and a recent bad experience being risk factors for suicidal ideation in men but not women. Relationship problems, problems at work and current psychotherapy use were positively associated with suicidal ideation in women but not in men. Thus, study dropout thoughts were associated with suicidal ideation in university students and there were male-specific risk patterns for suicidal ideation and associated mental health problems. Consequently, male university students reporting study dropout thoughts or financial stress should be screened for suicidality and mental health problems. Future prevention measures in the University context should consider study dropout thoughts and male-specific risk-patterns to increase the chances to detect male student’s suicidality and to improve the effectiveness of suicide prevention programs for men.
{"title":"Thoughts about dropping out of studies as warning sign for suicidal ideation and mental health problems in male university students","authors":"","doi":"10.22514/jomh.2023.072","DOIUrl":"https://doi.org/10.22514/jomh.2023.072","url":null,"abstract":"Despite increasing rates for suicidal ideation in university students, male students remain reluctant in reporting such thoughts. It is thus paramount to establish more easily detectable risk factors for male students. The present study examines study dropout thoughts as potential low-treshold risk factor as well as gender-differences in established risk patterns. A total of N = 4894 German university students (24.6% men) completed a cross-sectional online survey on their mental health at the University of Cologne. In addition to sociodemographic and questions related to university studies (e.g., dropping out of studies), the Patient Health Questionnaire D (PHQ-D) was used to assess psychological syndromes (any psychological syndrome, depressive syndrome, alcohol syndrome), life stressors and suicidal ideation. Study dropout thoughts were more prevalent among male students, while being associated with increased suicidal ideation for both genders assessed. For all outcomes, significant gender-differences were observed with financial stress and a recent bad experience being risk factors for suicidal ideation in men but not women. Relationship problems, problems at work and current psychotherapy use were positively associated with suicidal ideation in women but not in men. Thus, study dropout thoughts were associated with suicidal ideation in university students and there were male-specific risk patterns for suicidal ideation and associated mental health problems. Consequently, male university students reporting study dropout thoughts or financial stress should be screened for suicidality and mental health problems. Future prevention measures in the University context should consider study dropout thoughts and male-specific risk-patterns to increase the chances to detect male student’s suicidality and to improve the effectiveness of suicide prevention programs for men.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135058509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Since baseball players must grip and pinch the ball, grip strength is paramount. However, current assessments on various grip types need to be more comprehensive. This study aimed to determine the test-retest reliability of different handgrip strengths measured by a dynamometer connected to a player’s smartphone. Sixty male baseball players sponsored by secondary schools (middle- and high-schools) or colleges varying in age (12–22 years) were selected as participants. For male baseball players, three types of grip strengths were evaluated using a dynamometer and smartphone application: power, pinch, and tripod grip. The test was conducted thrice for each grip. Overall grip strength measurements showed slight decreases across tests and tended to increase with academic grade level. Tests 1 and 2 indicated good-to-excellent retest reliability for three grip strength positions by determining their intraclass correlation coefficients (ICCs) (middle-school power grip: 0.917 (0.644–0.973); collegiate pinch grip: 0.920 (0.770–0.970); high-school tripod grip: 0.929 (0.728–0.976)). In addition, these results determined moderate reliability compared to other grip strengths in the three groups (middle-school tripod grip from Tests 1 and 2: 0.779 (0.428–0.914); collegiate power grip from Tests 2 and 3: 0.738 (0.360–0.895)). This study concluded that the studied grip strength tests are reliable measurements, with an acceptable margin of error, for male baseball players from childhood to adulthood. Therefore, these handgrip strengths may be used as preliminary values to help discipline and rehabilitate baseball players and other athletes.
{"title":"Test-retest reliability of power, pinch, and tripod grip strengths in male baseball players: a preliminary study","authors":"","doi":"10.22514/jomh.2023.065","DOIUrl":"https://doi.org/10.22514/jomh.2023.065","url":null,"abstract":"Since baseball players must grip and pinch the ball, grip strength is paramount. However, current assessments on various grip types need to be more comprehensive. This study aimed to determine the test-retest reliability of different handgrip strengths measured by a dynamometer connected to a player’s smartphone. Sixty male baseball players sponsored by secondary schools (middle- and high-schools) or colleges varying in age (12–22 years) were selected as participants. For male baseball players, three types of grip strengths were evaluated using a dynamometer and smartphone application: power, pinch, and tripod grip. The test was conducted thrice for each grip. Overall grip strength measurements showed slight decreases across tests and tended to increase with academic grade level. Tests 1 and 2 indicated good-to-excellent retest reliability for three grip strength positions by determining their intraclass correlation coefficients (ICCs) (middle-school power grip: 0.917 (0.644–0.973); collegiate pinch grip: 0.920 (0.770–0.970); high-school tripod grip: 0.929 (0.728–0.976)). In addition, these results determined moderate reliability compared to other grip strengths in the three groups (middle-school tripod grip from Tests 1 and 2: 0.779 (0.428–0.914); collegiate power grip from Tests 2 and 3: 0.738 (0.360–0.895)). This study concluded that the studied grip strength tests are reliable measurements, with an acceptable margin of error, for male baseball players from childhood to adulthood. Therefore, these handgrip strengths may be used as preliminary values to help discipline and rehabilitate baseball players and other athletes.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135058513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sexuality should be able to be experienced in a healthy way. This can be affected by drug use in general and cocaine use in particular. Other aspects that can influence sexuality are anxiety and sexual attitudes. The main aim of this work is to explore and analyse how cocaine use affects men’s sexual response. In the present study, the GRISS (Golombok Rust Inventory of Sexual Satisfaction) questionnaire was used to assess sexual function, the SOS (Sexual Opinion Survey) questionnaire to evaluate sexual attitudes, and the STAI (State-Trait Anxiety Inventory) questionnaire to measure sexual anxiety. The sample consisted of 471 male cocaine users and 82 male non-users. The sampling was carried out in different treatment centres throughout Spain. The results indicate that male cocaine users score worse on the GRISS questionnaire, indicating a higher likelihood of sexual dysfunction, worse scores on the SOS questionnaire and higher anxiety levels. It is also observed that scores on the GRISS questionnaire did not improve over time. The differences were statistically significant and the initial study hypotheses were confirmed. The practical utility of this research lies in the applicability of these data in addiction treatment centres, and the potential for these centres to enhance specific interventions that promote healthy sexuality.
性应该以一种健康的方式来体验。这可能受到一般药物使用，特别是可卡因使用的影响。其他影响性行为的因素还有焦虑和性态度。这项工作的主要目的是探索和分析可卡因的使用如何影响男性的性反应。本研究采用GRISS (Golombok Rust Inventory of Sexual Satisfaction)量表评估性功能，SOS (Sexual Opinion Survey)量表评估性态度，STAI (State-Trait Anxiety Inventory)量表评估性焦虑。样本包括471名男性可卡因使用者和82名男性非可卡因使用者。抽样是在西班牙各地不同的治疗中心进行的。结果表明，男性可卡因使用者在GRISS问卷上得分较低，表明性功能障碍的可能性较高，SOS问卷得分较低，焦虑水平较高。我们还观察到，GRISS问卷的得分并没有随着时间的推移而提高。差异具有统计学意义，初步研究假设得到证实。这项研究的实际效用在于这些数据在成瘾治疗中心的适用性，以及这些中心加强促进健康性行为的具体干预措施的潜力。
{"title":"Prevalence of sexual dysfunction risk in cocaine users in a sample of Spanish men","authors":"","doi":"10.22514/jomh.2023.108","DOIUrl":"https://doi.org/10.22514/jomh.2023.108","url":null,"abstract":"Sexuality should be able to be experienced in a healthy way. This can be affected by drug use in general and cocaine use in particular. Other aspects that can influence sexuality are anxiety and sexual attitudes. The main aim of this work is to explore and analyse how cocaine use affects men’s sexual response. In the present study, the GRISS (Golombok Rust Inventory of Sexual Satisfaction) questionnaire was used to assess sexual function, the SOS (Sexual Opinion Survey) questionnaire to evaluate sexual attitudes, and the STAI (State-Trait Anxiety Inventory) questionnaire to measure sexual anxiety. The sample consisted of 471 male cocaine users and 82 male non-users. The sampling was carried out in different treatment centres throughout Spain. The results indicate that male cocaine users score worse on the GRISS questionnaire, indicating a higher likelihood of sexual dysfunction, worse scores on the SOS questionnaire and higher anxiety levels. It is also observed that scores on the GRISS questionnaire did not improve over time. The differences were statistically significant and the initial study hypotheses were confirmed. The practical utility of this research lies in the applicability of these data in addiction treatment centres, and the potential for these centres to enhance specific interventions that promote healthy sexuality.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"204 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135311417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The effect of Donabedian three-dimensional quality evaluation model is explored for the high-quality nursing during perioperative period of endoscopic mucosal dissection in early gastric cancer male patients. Seventy-eight early gastric cancer male patients were randomly grouped as 39 cases in control having received routine care, while 39 in the intervention group having received routine care combined with the three-dimensional quality evaluation model. Clinical recovery indicators including anxiety, depression, pain, life quality and complications were compared for the two groups. The intervention group’s clinical nursing recovery indicator scored higher than that of the control. The scores of each the short-form 36 item health survey questionnaire (SF-36) dimension were better than those of control, and the differences were statistically significant (p < 0.05). The incidence of complications in intervention group was 5.12%, and that in the control was 20.5%. The intervention group experienced less complications than the control, and the difference was statistically significant (p < 0.05). Treating early gastric cancer male patients with endoscopic mucosal dissection using three-dimensional quality evaluation model can improve clinical recovery and life quality, and reduce anxiety, depression, pain and complications.
{"title":"Application effect of a Donabedian three-dimensional quality evaluation model in perioperative nursing of early gastric cancer male patients undergoing endoscopic mucosal dissection","authors":"","doi":"10.22514/jomh.2023.078","DOIUrl":"https://doi.org/10.22514/jomh.2023.078","url":null,"abstract":"The effect of Donabedian three-dimensional quality evaluation model is explored for the high-quality nursing during perioperative period of endoscopic mucosal dissection in early gastric cancer male patients. Seventy-eight early gastric cancer male patients were randomly grouped as 39 cases in control having received routine care, while 39 in the intervention group having received routine care combined with the three-dimensional quality evaluation model. Clinical recovery indicators including anxiety, depression, pain, life quality and complications were compared for the two groups. The intervention group’s clinical nursing recovery indicator scored higher than that of the control. The scores of each the short-form 36 item health survey questionnaire (SF-36) dimension were better than those of control, and the differences were statistically significant (p < 0.05). The incidence of complications in intervention group was 5.12%, and that in the control was 20.5%. The intervention group experienced less complications than the control, and the difference was statistically significant (p < 0.05). Treating early gastric cancer male patients with endoscopic mucosal dissection using three-dimensional quality evaluation model can improve clinical recovery and life quality, and reduce anxiety, depression, pain and complications.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135058516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Engager is a complex, collaborative, but flexible intervention providing psychological and practical support to male prison leavers with sentences of two years or less. Engager was not shown to be effective from an evaluation of standard outcome measures, although full delivery of the intervention was also not achieved. The success of interventions relies partly on how able individuals are to attend, so we used an exploratory analysis of the Engager evaluation data to investigate what factors impacted on the extent to which participants attended Engager sessions. The results showed that problems with alcohol at baseline have a positive relationship with subsequent attendance (i.e., predict greater engagement). This finding was somewhat unexpected. Several other factors were found not to be predictive of either increased or decreased attendance, including depression, anxiety and psychological distress. This is a potentially positive finding, in that Engager appears to overcome some barriers to engagement in those with more severe common mental health issues, rather than them engaging less. This is despite previous evidence of these factors reducing attendance for mental health and psychological support. Potential reasons for these findings and implications for future research are discussed.
{"title":"Engagement with engager: what factors are associated with attendance in a complex intervention for men with common mental health problems, near to and after release from prison","authors":"","doi":"10.22514/jomh.2023.102","DOIUrl":"https://doi.org/10.22514/jomh.2023.102","url":null,"abstract":"Engager is a complex, collaborative, but flexible intervention providing psychological and practical support to male prison leavers with sentences of two years or less. Engager was not shown to be effective from an evaluation of standard outcome measures, although full delivery of the intervention was also not achieved. The success of interventions relies partly on how able individuals are to attend, so we used an exploratory analysis of the Engager evaluation data to investigate what factors impacted on the extent to which participants attended Engager sessions. The results showed that problems with alcohol at baseline have a positive relationship with subsequent attendance (i.e., predict greater engagement). This finding was somewhat unexpected. Several other factors were found not to be predictive of either increased or decreased attendance, including depression, anxiety and psychological distress. This is a potentially positive finding, in that Engager appears to overcome some barriers to engagement in those with more severe common mental health issues, rather than them engaging less. This is despite previous evidence of these factors reducing attendance for mental health and psychological support. Potential reasons for these findings and implications for future research are discussed.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135318058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Testosterone is an important male hormone, which could improve the maintenance and recovery of gonadal function in males as well as the repair of human hypospadias and cell fibrosis. Our study focused on investigating the regulatory effect of testosterone in human foreskin fibroblasts (HFF-1) and regulatory mechanisms involved. In this study, HFF-1 cells were treated with testosterone, and cell viability and migration were assessed by cell counting kit-8 (CCK8) and Transwell assays. The expression levels of androgen receptor (AR), miR-143-3p and insulin-like growth factor binding protein-3 (IGFBP-3) were measured by quantitative real-time PCR (qRT-PCR), Western blotting, and immunofluorescence. In addition, a potential binding site for miR-143-3p on IGFBP-3 was predicted and its direct binding was further confirmed by a dual luciferase reporter assay. These results showed that testosterone increased the viability and migration of HFF-1 cells. Testosterone could down-regulate miR-143-3p and up-regulate IGFBP-3 and AR. Overexpression of miR-143-3p hindered HFF-1 cell viability and negatively regulated IGFBP-3, whereas inhibition of IGFBP-3 impeded cell viability and migration. Furthermore, miR-143-3p was found to directly bind to IGFBP-3. Overexpression of IGFBP-3 countered the regulation of HFF-1 cells by miR-143-3p mimics. In conclusion, this study showed that testosterone promoted the proliferation and migration of HFF-1 cells and AR signaling, at least via the miR-143-3p/IGFBP-3 axis. This discovery presents a novel insight for testosterone application in male disorders like hypospadias.
{"title":"Testosterone promotes human foreskin fibroblast growth through miR-143-3p targeting IGFBP-3","authors":"","doi":"10.22514/jomh.2023.082","DOIUrl":"https://doi.org/10.22514/jomh.2023.082","url":null,"abstract":"Testosterone is an important male hormone, which could improve the maintenance and recovery of gonadal function in males as well as the repair of human hypospadias and cell fibrosis. Our study focused on investigating the regulatory effect of testosterone in human foreskin fibroblasts (HFF-1) and regulatory mechanisms involved. In this study, HFF-1 cells were treated with testosterone, and cell viability and migration were assessed by cell counting kit-8 (CCK8) and Transwell assays. The expression levels of androgen receptor (AR), miR-143-3p and insulin-like growth factor binding protein-3 (IGFBP-3) were measured by quantitative real-time PCR (qRT-PCR), Western blotting, and immunofluorescence. In addition, a potential binding site for miR-143-3p on IGFBP-3 was predicted and its direct binding was further confirmed by a dual luciferase reporter assay. These results showed that testosterone increased the viability and migration of HFF-1 cells. Testosterone could down-regulate miR-143-3p and up-regulate IGFBP-3 and AR. Overexpression of miR-143-3p hindered HFF-1 cell viability and negatively regulated IGFBP-3, whereas inhibition of IGFBP-3 impeded cell viability and migration. Furthermore, miR-143-3p was found to directly bind to IGFBP-3. Overexpression of IGFBP-3 countered the regulation of HFF-1 cells by miR-143-3p mimics. In conclusion, this study showed that testosterone promoted the proliferation and migration of HFF-1 cells and AR signaling, at least via the miR-143-3p/IGFBP-3 axis. This discovery presents a novel insight for testosterone application in male disorders like hypospadias.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135801085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erectile dysfunction (ED) has been closely associated with both high blood pressure (HBP) and psychological traits, but the causal relationship between them remains unclear. Herein, we aimed to identify the causal risk factors for ED. We conducted univariable and multivariable Mendelian randomization (MR) analyses using genetic variants associated with metabolic syndrome and psychology traits at the genome-wide significance (p < 5 × 10−8) level obtained from corresponding genome-wide association studies. We used summary-level statistical data for ED from the European Bioinformatics Institute (EBI) database of complete Genome-Wide Association Studies (GWAS) summary data. We also conducted reverse causality and performed power calculations for MR. Our results showed that HBP was associated with increased odds of ED (odds ratio (OR) = 1.66 (95% confidence interval (CI), 1.13–2.45), a p-value for the inverse variance-weighted method (PIVW ) = 1.06 × 10−2, Power = 100%), as were myocardial infarction (OR = 1.09 (95% CI, 1.02–1.17), PIVW = 1.18 × 10−2, Power = 56%) and ischemic stroke (OR = 1.21 (95% CI, 1.02–1.43), PIVW = 2.87 × 10−2, Power = 10%). In terms of psychological traits, irritable mood (OR = 1.86 (95% CI, 1.14–3.02), PIVW = 1.30 × 10−2, Power = 96%) and neuroticism (OR = 1.36 (95% CI, 1.04–1.79), PIVW = 2.66 × 10−2, Power = 80%) were associated with increased odds of ED. Mendelian randomization pleiotropy residual sum and outlier (MR-PRESSO) showed no evidence of pleiotropic bias, and sensitivity analyses confirmed the robustness of our results. We have established a causal link between HBP and ED, and we have also found evidence suggesting a causal relationship between irritable mood and ED.
{"title":"Causal associations between erectile dysfunction and high blood pressure, negative psychology: a Mendelian randomization study","authors":"","doi":"10.22514/jomh.2023.084","DOIUrl":"https://doi.org/10.22514/jomh.2023.084","url":null,"abstract":"Erectile dysfunction (ED) has been closely associated with both high blood pressure (HBP) and psychological traits, but the causal relationship between them remains unclear. Herein, we aimed to identify the causal risk factors for ED. We conducted univariable and multivariable Mendelian randomization (MR) analyses using genetic variants associated with metabolic syndrome and psychology traits at the genome-wide significance (p < 5 × 10−8) level obtained from corresponding genome-wide association studies. We used summary-level statistical data for ED from the European Bioinformatics Institute (EBI) database of complete Genome-Wide Association Studies (GWAS) summary data. We also conducted reverse causality and performed power calculations for MR. Our results showed that HBP was associated with increased odds of ED (odds ratio (OR) = 1.66 (95% confidence interval (CI), 1.13–2.45), a p-value for the inverse variance-weighted method (PIVW ) = 1.06 × 10−2, Power = 100%), as were myocardial infarction (OR = 1.09 (95% CI, 1.02–1.17), PIVW = 1.18 × 10−2, Power = 56%) and ischemic stroke (OR = 1.21 (95% CI, 1.02–1.43), PIVW = 2.87 × 10−2, Power = 10%). In terms of psychological traits, irritable mood (OR = 1.86 (95% CI, 1.14–3.02), PIVW = 1.30 × 10−2, Power = 96%) and neuroticism (OR = 1.36 (95% CI, 1.04–1.79), PIVW = 2.66 × 10−2, Power = 80%) were associated with increased odds of ED. Mendelian randomization pleiotropy residual sum and outlier (MR-PRESSO) showed no evidence of pleiotropic bias, and sensitivity analyses confirmed the robustness of our results. We have established a causal link between HBP and ED, and we have also found evidence suggesting a causal relationship between irritable mood and ED.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"2015 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135801092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This cross-sectional study correlated the muscle mass reduction with serum uric acid and urinary albumin in middle-aged and elderly men having type 2 diabetes. The study subjects were 288 middle-aged and elderly male patients with type 2 diabetes (T2DM) admitted to our hospital. They were divided into sarcopenia (n = 95) and non-sarcopenia (n = 193) groups based on whether diagnosed with sarcopenia or not. The relevant clinical information of patients was collected. Single factor analysis and multiple factor regression analysis were employed to explore the influencing factors of sarcopenia. A binary logistic regression analysis model was established for the sarcopenia probability in middle-aged and elderly men with T2DM. Hosmer and Lemeshow test evaluated the Goodness of fit of probability model. ROC (Receiver Operating Characteristic) curve was drawn by SPSS and the predictive value of prediction model was evaluated. The univariate analysis depicted that the patients in sarcopenia group compared to those in non-sarcopenia were older with lower BMI (Body Mass Index), lower UA (Uric Acid) and higher CRP (C-reactive Protein). The differences were statistically significant (p < 0.05). The binary logistic regression analysis exhibited that the age and UACR (Urine Albumin-to-Creatinine Ratio) were the risk factors, while BMI and UA were the protective factors for sarcopenia in middle-aged and elderly men with T2DM. For middle-aged and elderly male patients with T2DM, age and UACR were the risk factors, and BMI and UA were the protective factors for sarcopenia. The changes in above-stated indicators of patients with T2DM should be clinically monitored, and early and active intervention be given to high-risk groups for minimizing the sarcopenia occurrence.
{"title":"Correlation between muscle mass reduction and serum uric acid and urinary albumin in middle-aged and elderly type 2 diabetes men","authors":"","doi":"10.22514/jomh.2023.089","DOIUrl":"https://doi.org/10.22514/jomh.2023.089","url":null,"abstract":"This cross-sectional study correlated the muscle mass reduction with serum uric acid and urinary albumin in middle-aged and elderly men having type 2 diabetes. The study subjects were 288 middle-aged and elderly male patients with type 2 diabetes (T2DM) admitted to our hospital. They were divided into sarcopenia (n = 95) and non-sarcopenia (n = 193) groups based on whether diagnosed with sarcopenia or not. The relevant clinical information of patients was collected. Single factor analysis and multiple factor regression analysis were employed to explore the influencing factors of sarcopenia. A binary logistic regression analysis model was established for the sarcopenia probability in middle-aged and elderly men with T2DM. Hosmer and Lemeshow test evaluated the Goodness of fit of probability model. ROC (Receiver Operating Characteristic) curve was drawn by SPSS and the predictive value of prediction model was evaluated. The univariate analysis depicted that the patients in sarcopenia group compared to those in non-sarcopenia were older with lower BMI (Body Mass Index), lower UA (Uric Acid) and higher CRP (C-reactive Protein). The differences were statistically significant (p < 0.05). The binary logistic regression analysis exhibited that the age and UACR (Urine Albumin-to-Creatinine Ratio) were the risk factors, while BMI and UA were the protective factors for sarcopenia in middle-aged and elderly men with T2DM. For middle-aged and elderly male patients with T2DM, age and UACR were the risk factors, and BMI and UA were the protective factors for sarcopenia. The changes in above-stated indicators of patients with T2DM should be clinically monitored, and early and active intervention be given to high-risk groups for minimizing the sarcopenia occurrence.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135801329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We aimed to evaluate the efficacy of combined low-intensity extracorporeal shockwave therapy (LI-ESWT) and dapoxetine administration for the treatment of lifelong premature ejaculation (LPE) in comparison to LI-ESWT and dapoxetine alone. In the randomized controlled trial, 212 men diagnosed with LPE were enrolled. The participants were randomized into four subgroups: control (n = 50), dapoxetine (n = 56), LI-ESWT (n = 50) and LI-ESWT + dapoxetine (n = 56). The intravaginal ejaculation latency (IELT), premature ejaculation profile (PEP), and Global Impression of Change (GIC) were evaluated. There were substantial improvements in the fold-increase of the IELT (F-IELT), and PEP and GIC-I scores in both the dapoxetine (p < 0.001) and LI-ESWT + Dapoxetine (p < 0.001) groups than in the control and LI-ESWT groups. Although the LI-ESWT group demonstrated a minor improvement in the F-IELT score (p = 0.04), there were no noticeable improvements in the PEP (p = 0.12) and GIC-I (p = 0.15) scores. In conclusion, a combination of dapoxetine administration and LI-ESWT might be more effective in treating LPE than LI-ESWT or dapoxetine alone, indicating a potential synergistic effect.
{"title":"A randomized controlled trial of combined low-intensity extracorporeal shockwave therapy and Dapoxetine use in the management of lifelong premature ejaculation","authors":"","doi":"10.22514/jomh.2023.076","DOIUrl":"https://doi.org/10.22514/jomh.2023.076","url":null,"abstract":"We aimed to evaluate the efficacy of combined low-intensity extracorporeal shockwave therapy (LI-ESWT) and dapoxetine administration for the treatment of lifelong premature ejaculation (LPE) in comparison to LI-ESWT and dapoxetine alone. In the randomized controlled trial, 212 men diagnosed with LPE were enrolled. The participants were randomized into four subgroups: control (n = 50), dapoxetine (n = 56), LI-ESWT (n = 50) and LI-ESWT + dapoxetine (n = 56). The intravaginal ejaculation latency (IELT), premature ejaculation profile (PEP), and Global Impression of Change (GIC) were evaluated. There were substantial improvements in the fold-increase of the IELT (F-IELT), and PEP and GIC-I scores in both the dapoxetine (p < 0.001) and LI-ESWT + Dapoxetine (p < 0.001) groups than in the control and LI-ESWT groups. Although the LI-ESWT group demonstrated a minor improvement in the F-IELT score (p = 0.04), there were no noticeable improvements in the PEP (p = 0.12) and GIC-I (p = 0.15) scores. In conclusion, a combination of dapoxetine administration and LI-ESWT might be more effective in treating LPE than LI-ESWT or dapoxetine alone, indicating a potential synergistic effect.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135057905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
It is well established that the prevalence of Traumatic Brain Injury (TBI) is higher in offender populations than the general population. Men in prison and probation services also have many of the risk factors that place them at higher risk of developing neuropsychiatric complications following a TBI (e.g., low socioeconomic backgrounds, previous history of substance misuse). The BIL service, developed in 2013 by Brainkind (formally The Disabilities Trust) delivers brain injury rehabilitation to men engaged with South Wales (United Kingdom) Prison and Probation Services. As part of a wider service evaluation, we reviewed the levels of anxiety (Generalised Anxiety Disorder assessment, GAD-7) and depression (Patient Health Questionnaire, PHQ-9) of 50 men in prison or on probation pre- and post-BIL intervention. Results showed a significant decrease in the scores reported on the GAD-7 between the start (Mean—M = 15.38, Standard Deviation—SD = 4.64) and end (M = 11.84, SD = 5.15) of the intervention (t (49) = 2.01, p = 0.00000733). Additionally, there was a significant decrease in self-reported depression symptoms as observed by the scores on the PHQ-9 between the start (M = 17.08, SD = 5.55) and end (M = 12.42, SD = 6.55) of the intervention (t (49) = 2.01, p = 0.0000125). These results indicate that overall there was an improvement in the men’s levels of anxiety and depression following the BIL intervention. This service evaluation provides a clear rationale for the development of a more rigorous research protocol to explore the relationship between brain injury interventions and the impact on mental health in this population.
{"title":"A service evaluation on the impact of brain injury linkworker (BIL) interventions on the anxiety and depression of men in prison and on probation","authors":"","doi":"10.22514/jomh.2023.109","DOIUrl":"https://doi.org/10.22514/jomh.2023.109","url":null,"abstract":"It is well established that the prevalence of Traumatic Brain Injury (TBI) is higher in offender populations than the general population. Men in prison and probation services also have many of the risk factors that place them at higher risk of developing neuropsychiatric complications following a TBI (e.g., low socioeconomic backgrounds, previous history of substance misuse). The BIL service, developed in 2013 by Brainkind (formally The Disabilities Trust) delivers brain injury rehabilitation to men engaged with South Wales (United Kingdom) Prison and Probation Services. As part of a wider service evaluation, we reviewed the levels of anxiety (Generalised Anxiety Disorder assessment, GAD-7) and depression (Patient Health Questionnaire, PHQ-9) of 50 men in prison or on probation pre- and post-BIL intervention. Results showed a significant decrease in the scores reported on the GAD-7 between the start (Mean—M = 15.38, Standard Deviation—SD = 4.64) and end (M = 11.84, SD = 5.15) of the intervention (t (49) = 2.01, p = 0.00000733). Additionally, there was a significant decrease in self-reported depression symptoms as observed by the scores on the PHQ-9 between the start (M = 17.08, SD = 5.55) and end (M = 12.42, SD = 6.55) of the intervention (t (49) = 2.01, p = 0.0000125). These results indicate that overall there was an improvement in the men’s levels of anxiety and depression following the BIL intervention. This service evaluation provides a clear rationale for the development of a more rigorous research protocol to explore the relationship between brain injury interventions and the impact on mental health in this population.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135261913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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