首页 > 最新文献

Journal of Men's Health最新文献

英文 中文
The efficacy of different training programs guided by cardiopulmonary exercise test goals for the treatment of male patients with chronic obstructive pulmonary disease 以心肺运动试验目标为指导的不同训练方案对男性慢性阻塞性肺疾病患者的治疗效果
4区 医学 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.22514/jomh.2023.093
To explore the therapeutic effect of aerobic exercise nursing plans based on target heart rate in cardiopulmonary exercise tests on male patients with chronic obstructive pulmonary disease. This study recruited 90 male patients with chronic obstructive pulmonary disease who met specific screening criteria and were evenly divided into a control group and an experimental group based on a random number table. The control group received respiratory training based on the target heart rate in the cardiopulmonary exercise test, while the experimental group received aerobic exercise based on the target heart rate in the cardiopulmonary exercise test. Both groups received 12 weeks of exercise each. Cardiopulmonary function tests showed that peak oxygen consumption (peak VO2), anaerobic threshold (AT), forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), and the FEV1/FVC ratio in the test group were significantly higher than those in the control group (p < 0.05); furthermore, the carbon dioxide ventilation equivalent (VE/VCO2) slope was significantly lower than that in the control group (p < 0.05). The 6MWT of the test group was significantly higher than that in the control group (p < 0.05). The CAT score, Borg score and scores related to the symptoms, activities, and impacts related to quality-of-life were significantly reduced after intervention (p < 0.05). Aerobic exercise based on cardiopulmonary exercise testing can improve the health status, quality of life and prognosis of COPD patients.
探讨基于心肺运动试验目标心率的有氧运动护理方案对男性慢性阻塞性肺疾病患者的治疗效果。本研究招募符合特定筛查标准的男性慢性阻塞性肺疾病患者90例,采用随机数字表法将其平均分为对照组和实验组。对照组根据心肺运动试验的目标心率进行呼吸训练,实验组根据心肺运动试验的目标心率进行有氧运动。两组都接受了12周的锻炼。心肺功能测试结果显示,试验组患者的峰值耗氧量(peak VO2)、无氧阈值(AT)、第一秒用力呼气量(FEV1)、用力肺活量(FVC)、FEV1/FVC比值显著高于对照组(p <二氧化碳通气量当量(VE/VCO2)斜率显著低于对照组(p <0.05)。试验组6MWT显著高于对照组(p <0.05)。CAT评分、Borg评分以及与症状、活动和与生活质量相关的影响相关的评分在干预后显著降低(p <0.05)。以心肺运动试验为基础的有氧运动可以改善COPD患者的健康状况、生活质量和预后。
{"title":"The efficacy of different training programs guided by cardiopulmonary exercise test goals for the treatment of male patients with chronic obstructive pulmonary disease","authors":"","doi":"10.22514/jomh.2023.093","DOIUrl":"https://doi.org/10.22514/jomh.2023.093","url":null,"abstract":"To explore the therapeutic effect of aerobic exercise nursing plans based on target heart rate in cardiopulmonary exercise tests on male patients with chronic obstructive pulmonary disease. This study recruited 90 male patients with chronic obstructive pulmonary disease who met specific screening criteria and were evenly divided into a control group and an experimental group based on a random number table. The control group received respiratory training based on the target heart rate in the cardiopulmonary exercise test, while the experimental group received aerobic exercise based on the target heart rate in the cardiopulmonary exercise test. Both groups received 12 weeks of exercise each. Cardiopulmonary function tests showed that peak oxygen consumption (peak VO2), anaerobic threshold (AT), forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), and the FEV1/FVC ratio in the test group were significantly higher than those in the control group (p < 0.05); furthermore, the carbon dioxide ventilation equivalent (VE/VCO2) slope was significantly lower than that in the control group (p < 0.05). The 6MWT of the test group was significantly higher than that in the control group (p < 0.05). The CAT score, Borg score and scores related to the symptoms, activities, and impacts related to quality-of-life were significantly reduced after intervention (p < 0.05). Aerobic exercise based on cardiopulmonary exercise testing can improve the health status, quality of life and prognosis of COPD patients.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135801094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender difference in impact of mental health during the COVID-19 pandemic on sexual function COVID-19大流行期间心理健康对性功能影响的性别差异
4区 医学 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.22514/jomh.2023.104
There is a paucity of research on the difference between men and women in the impact of mental health on sexual function during the coronavirus disease (COVID-19) pandemic. This study aims to explore sexual function changes and the effects of mental health on sexual function during the COVID-19 pandemic. The data from a self-administered online questionnaire completed by 180 healthy Korean volunteers were analyzed. During the COVID-19 pandemic, women tended to be more vulnerable than men in all subscales of the Depression, Anxiety and Stress Scale 21 (DASS-21), except for the stress subscale (p < 0.001). Regarding sexual function, overall sexual function, including both the total International Index of Erectile Function-5 (IIEF-5) score and total Female Sexual Function Index (FSFI) score, was lower during the pandemic compared to before the pandemic. All subscales of DASS-21 and total DASS-21 scores were negatively correlated with total IIEF-5 and total FSFI score in men and women, respectively. On a multivariate analysis, the anxiety subscale of DASS-21 was an independent risk factor for decreased total IIEF-5 score in men (p < 0.05). Mental health during the pandemic has negatively influenced sexual function in both sexes. Particularly, anxiety was a significant risk factor for decreased erectile function in men during the pandemic.
在冠状病毒病(COVID-19)大流行期间,男性和女性在心理健康对性功能影响方面的差异研究很少。本研究旨在探讨新冠肺炎大流行期间的性功能变化及心理健康对性功能的影响。180名健康的韩国志愿者完成了一份自我管理的在线问卷,对问卷数据进行了分析。在2019冠状病毒病大流行期间,在抑郁、焦虑和压力量表21 (DASS-21)的所有子量表中,女性往往比男性更脆弱,除了压力子量表(p <0.001)。在性功能方面,总体性功能,包括国际勃起功能指数-5 (IIEF-5)总分和女性性功能指数(FSFI)总分,在大流行期间比大流行前更低。DASS-21各分量表和DASS-21总分分别与男性和女性的IIEF-5总分和FSFI总分呈负相关。在多变量分析中,DASS-21的焦虑分量表是男性IIEF-5总分下降的独立危险因素(p <0.05)。大流行期间的心理健康对两性性功能都产生了负面影响。特别是,焦虑是大流行期间男性勃起功能下降的一个重要风险因素。
{"title":"Gender difference in impact of mental health during the COVID-19 pandemic on sexual function","authors":"","doi":"10.22514/jomh.2023.104","DOIUrl":"https://doi.org/10.22514/jomh.2023.104","url":null,"abstract":"There is a paucity of research on the difference between men and women in the impact of mental health on sexual function during the coronavirus disease (COVID-19) pandemic. This study aims to explore sexual function changes and the effects of mental health on sexual function during the COVID-19 pandemic. The data from a self-administered online questionnaire completed by 180 healthy Korean volunteers were analyzed. During the COVID-19 pandemic, women tended to be more vulnerable than men in all subscales of the Depression, Anxiety and Stress Scale 21 (DASS-21), except for the stress subscale (p < 0.001). Regarding sexual function, overall sexual function, including both the total International Index of Erectile Function-5 (IIEF-5) score and total Female Sexual Function Index (FSFI) score, was lower during the pandemic compared to before the pandemic. All subscales of DASS-21 and total DASS-21 scores were negatively correlated with total IIEF-5 and total FSFI score in men and women, respectively. On a multivariate analysis, the anxiety subscale of DASS-21 was an independent risk factor for decreased total IIEF-5 score in men (p < 0.05). Mental health during the pandemic has negatively influenced sexual function in both sexes. Particularly, anxiety was a significant risk factor for decreased erectile function in men during the pandemic.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"121 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135316671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Profiles of conformity to gender role norms and depression among adult Korean men 韩国成年男性对性别角色规范的遵从与抑郁状况
4区 医学 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.22514/jomh.2023.100
Socioeconomic polarization have consequences for men seeking a traditional male image; consequently, the pattern of conformity to gender role norms is changing. Taking into account an actor-oriented perspective, this study hypothesized that adherence to gender role norms would vary among male groups and would be associated with differences in mental health, specifically in terms of depressive symptoms. For verification, a Gender Roles and Health Survey was conducted with 897 Korean men aged 19–69 years between January and February 2022 to assess male gender roles, traditional gender role attitudes, and descriptive masculine norms, and to measure participants’ level of depressive symptoms using the 8-item Center for Epidemiological Studies Depression scale. Four latent profiles—“high conformity”, “medium conformity”, “non-conformity to gender stereotypes” and “non-conformity to male gender roles”—were identified. The non-conformity to male gender roles profile, which entails accepting traditional gender stereotypes, was associated with a significantly higher depression score. This profile also exhibited the characteristics of lower age, lower household income and being unmarried or not living with a partner. The non-conformity to gender stereotypes profile showed the lowest depression score. Based on the study findings, individuals who deviate from gender role norms, particularly in terms of self-ascribed masculinity, are more likely to experience depression. This suggests that the relationship between adherence to gender role norms and men’s mental health is complex and varied.
社会经济两极分化对男性寻求传统男性形象产生了影响;因此,符合性别角色规范的模式正在发生变化。考虑到行为者导向的观点,这项研究假设,对性别角色规范的遵守在男性群体中会有所不同,并与心理健康的差异有关,特别是在抑郁症状方面。为了验证,在2022年1月至2月期间,对897名年龄在19-69岁的韩国男性进行了性别角色和健康调查,以评估男性性别角色、传统性别角色态度和描述性男性规范,并使用8项流行病学研究中心抑郁量表测量参与者的抑郁症状水平。发现了四种潜在特征——“高度从众”、“中等从众”、“不符合性别刻板印象”和“不符合男性性别角色”。不符合男性性别角色形象,即接受传统的性别刻板印象,与抑郁得分显著升高有关。该剖面还表现出年龄较低、家庭收入较低、未婚或无伴侣生活的特征。不符合性别刻板印象者抑郁得分最低。根据研究结果,偏离性别角色规范的人,特别是在自我认定的男子气概方面,更有可能患上抑郁症。这表明,遵守性别角色规范与男性心理健康之间的关系是复杂而多样的。
{"title":"Profiles of conformity to gender role norms and depression among adult Korean men","authors":"","doi":"10.22514/jomh.2023.100","DOIUrl":"https://doi.org/10.22514/jomh.2023.100","url":null,"abstract":"Socioeconomic polarization have consequences for men seeking a traditional male image; consequently, the pattern of conformity to gender role norms is changing. Taking into account an actor-oriented perspective, this study hypothesized that adherence to gender role norms would vary among male groups and would be associated with differences in mental health, specifically in terms of depressive symptoms. For verification, a Gender Roles and Health Survey was conducted with 897 Korean men aged 19–69 years between January and February 2022 to assess male gender roles, traditional gender role attitudes, and descriptive masculine norms, and to measure participants’ level of depressive symptoms using the 8-item Center for Epidemiological Studies Depression scale. Four latent profiles—“high conformity”, “medium conformity”, “non-conformity to gender stereotypes” and “non-conformity to male gender roles”—were identified. The non-conformity to male gender roles profile, which entails accepting traditional gender stereotypes, was associated with a significantly higher depression score. This profile also exhibited the characteristics of lower age, lower household income and being unmarried or not living with a partner. The non-conformity to gender stereotypes profile showed the lowest depression score. Based on the study findings, individuals who deviate from gender role norms, particularly in terms of self-ascribed masculinity, are more likely to experience depression. This suggests that the relationship between adherence to gender role norms and men’s mental health is complex and varied.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"162 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135318042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sugar-sweetened beverage consumption and sleep duration among adult men: the role of race and ethnicity 成年男性含糖饮料的摄入量和睡眠时间:种族和民族的作用
4区 医学 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.22514/jomh.2023.070
Less attention has been given to the relationship between the consumption of sugar-sweetened beverages and sleep among adult men, even though they are a group that consumes a large amount of sugar-sweetened beverages and who has worse sleep duration than women. The purpose of the current study is to explore the association between the consumption of sugar-sweetened beverages and sleep duration and to investigate how the relationship differs by race and ethnicity among adult men. The current study employed a secondary dataset—the National Longitudinal Survey of Youth 1979 for Children and Young Adults. A total of 2609 participants were selected for analysis. A moderation model was employed to explore the moderating effect of race and ethnicity on the relationship between sugar-sweetened beverage consumption and sleep duration. The consumption of sugar-sweetened beverages among adult men was negatively related to their sleep duration (p < 0.01). The association between the consumption of sugar-sweetened beverages and sleep duration among adult men was moderated by Hispanic identity (p < 0.05). Unlike for White adult men, whose sleep duration may be significantly affected by the reduced consumption of sugar-sweetened beverages, addressing other factors such as stress associated with discrimination in the workplace or the job market may be more important to enhance Hispanic adult men’s sleep duration. Alternative options such as unsweetened teas, 100% fruit juice, or water may be emphasized in education may be emphasized to substitute at least some sugar-sweetened beverages to improve adult men’s poor sleep duration.
很少有人关注成年男性饮用含糖饮料与睡眠之间的关系,尽管他们是一个消费大量含糖饮料的群体,而且睡眠时间比女性差。目前这项研究的目的是探索含糖饮料的摄入量与睡眠时间之间的关系,并调查成年男性的种族和民族之间的关系有何不同。目前的研究采用了一个辅助数据——1979年全国青少年纵向调查的儿童和年轻人。共选取2609名参与者进行分析。采用调节模型探讨种族和民族对含糖饮料消费与睡眠时间关系的调节作用。成年男性饮用含糖饮料与睡眠时间呈负相关(p <0.01)。在成年男性中,含糖饮料的摄入量与睡眠时间之间的关系被西班牙裔身份所缓和(p <0.05)。与白人成年男性不同,白人成年男性的睡眠时间可能会受到含糖饮料消费量减少的显著影响,而解决其他因素,如与工作场所或就业市场歧视相关的压力,可能对提高西班牙裔成年男性的睡眠时间更为重要。其他的选择,如不加糖的茶,100%的果汁,或水,可以在教育中强调,可以强调至少一些含糖饮料的替代品,以改善成年男性的睡眠时间。
{"title":"Sugar-sweetened beverage consumption and sleep duration among adult men: the role of race and ethnicity","authors":"","doi":"10.22514/jomh.2023.070","DOIUrl":"https://doi.org/10.22514/jomh.2023.070","url":null,"abstract":"Less attention has been given to the relationship between the consumption of sugar-sweetened beverages and sleep among adult men, even though they are a group that consumes a large amount of sugar-sweetened beverages and who has worse sleep duration than women. The purpose of the current study is to explore the association between the consumption of sugar-sweetened beverages and sleep duration and to investigate how the relationship differs by race and ethnicity among adult men. The current study employed a secondary dataset—the National Longitudinal Survey of Youth 1979 for Children and Young Adults. A total of 2609 participants were selected for analysis. A moderation model was employed to explore the moderating effect of race and ethnicity on the relationship between sugar-sweetened beverage consumption and sleep duration. The consumption of sugar-sweetened beverages among adult men was negatively related to their sleep duration (p < 0.01). The association between the consumption of sugar-sweetened beverages and sleep duration among adult men was moderated by Hispanic identity (p < 0.05). Unlike for White adult men, whose sleep duration may be significantly affected by the reduced consumption of sugar-sweetened beverages, addressing other factors such as stress associated with discrimination in the workplace or the job market may be more important to enhance Hispanic adult men’s sleep duration. Alternative options such as unsweetened teas, 100% fruit juice, or water may be emphasized in education may be emphasized to substitute at least some sugar-sweetened beverages to improve adult men’s poor sleep duration.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135058508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparative study of stigma and mental health status between patients with erectile dysfunction and patients with erectile dysfunction and diabetes 勃起功能障碍患者与勃起功能障碍合并糖尿病患者的耻辱感及心理健康状况比较研究
4区 医学 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.22514/jomh.2023.069
Recently, although stigma and mental health among patients with diabetes have garnered significant research attention, there are still limited investigations into the stigma and mental health of patients with erectile dysfunction (ED) and diabetes. In this study, we aimed to examine the stigma and mental health of patients with ED and diabetes to provide insights for improving the treatment and nursing of patients with ED and diabetes. We selected 82 patients with ED and diabetes and 82 patients with ED. Patients were evaluated using the Basic Information Scale, Symptom Checklist 90 (SCL-90) and Social Impact Scale (SIS). Patients with ED and diabetes had higher scores than the national norm in all dimensions of shame (p < 0.05), while patients with ED scored higher than the national norm in the dimensions of social exclusion, economic discrimination and internal shame (p < 0.05). Further, patients with ED and diabetes had higher scores of disease shame regarding social exclusion, internal shame and social isolation dimensions than patients with ED (p < 0.05). The score of interpersonal relationship factors of patients with ED was lower than that of the national norm (p < 0.05), while for patients with ED, the score of interpersonal relationship factors in patients’ SCL-90 was lower (p < 0.05) and the score of psychotic factors was higher than that of the national norm (p < 0.05). A positive correlation was observed between the paranoid factor score in the SCL-90 of patients with ED and diabetes, the social exclusion dimension score, and the total score in the sense of shame (p < 0.05). Both patients with ED and diabetes and patients with ED exhibited abnormally higher rates of SCL-90 scores, indicating the presence of psychological distress and urging the need to strengthen psychological care.
近年来,虽然糖尿病患者的耻辱感和心理健康已经引起了大量的研究关注,但对勃起功能障碍(ED)和糖尿病患者的耻辱感和心理健康的研究仍然有限。在本研究中,我们旨在探讨ED和糖尿病患者的耻辱感和心理健康状况,为改善ED和糖尿病患者的治疗和护理提供见解。选取ED合并糖尿病患者82例和ED患者82例,采用基本信息量表、症状自评量表(SCL-90)和社会影响量表(SIS)对患者进行评估。ED和糖尿病患者在羞耻的所有维度上的得分都高于国家标准(p <而ED患者在社会排斥、经济歧视和内在羞耻感维度得分高于全国常模(p <0.05)。此外,ED和糖尿病患者在社会排斥、内在羞耻和社会孤立维度上的疾病羞耻感得分高于ED患者(p <0.05)。ED患者人际关系因素得分低于全国常模(p <0.05),而ED患者的人际关系因素在SCL-90中的得分较低(p <0.05),精神因素得分高于全国常模(p <0.05)。ED合并糖尿病患者SCL-90偏执因子得分与社会排斥维度得分、羞耻感总分呈显著正相关(p <0.05)。ED合并糖尿病患者和ED患者的SCL-90得分均异常高,提示存在心理困扰,需要加强心理护理。
{"title":"A comparative study of stigma and mental health status between patients with erectile dysfunction and patients with erectile dysfunction and diabetes","authors":"","doi":"10.22514/jomh.2023.069","DOIUrl":"https://doi.org/10.22514/jomh.2023.069","url":null,"abstract":"Recently, although stigma and mental health among patients with diabetes have garnered significant research attention, there are still limited investigations into the stigma and mental health of patients with erectile dysfunction (ED) and diabetes. In this study, we aimed to examine the stigma and mental health of patients with ED and diabetes to provide insights for improving the treatment and nursing of patients with ED and diabetes. We selected 82 patients with ED and diabetes and 82 patients with ED. Patients were evaluated using the Basic Information Scale, Symptom Checklist 90 (SCL-90) and Social Impact Scale (SIS). Patients with ED and diabetes had higher scores than the national norm in all dimensions of shame (p < 0.05), while patients with ED scored higher than the national norm in the dimensions of social exclusion, economic discrimination and internal shame (p < 0.05). Further, patients with ED and diabetes had higher scores of disease shame regarding social exclusion, internal shame and social isolation dimensions than patients with ED (p < 0.05). The score of interpersonal relationship factors of patients with ED was lower than that of the national norm (p < 0.05), while for patients with ED, the score of interpersonal relationship factors in patients’ SCL-90 was lower (p < 0.05) and the score of psychotic factors was higher than that of the national norm (p < 0.05). A positive correlation was observed between the paranoid factor score in the SCL-90 of patients with ED and diabetes, the social exclusion dimension score, and the total score in the sense of shame (p < 0.05). Both patients with ED and diabetes and patients with ED exhibited abnormally higher rates of SCL-90 scores, indicating the presence of psychological distress and urging the need to strengthen psychological care.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135058512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Upregulation of the ZWINT expression correlates with prostate cancer progression and immune infiltration ZWINT表达上调与前列腺癌进展和免疫浸润相关
4区 医学 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.22514/jomh.2023.085
Prostate cancer (PCa), the most prevalent epithelial malignant neoplasm in the male group globally, is the fifth largest cause of cancer-related death in males. ZW10 Interactor (ZWINT) is involved in the chromosome segregation process, which is linked to the formation of several tumor cells. However, its function in PCa remains unknown. Therefore, our aim was to explore the potential mechanisms of ZWINT in PCa progression. We obtained RNA-seq as well as clinical data from The Cancer Genome Atlas Program (TCGA), University of California Santa Cruz (UCSC) database. Assessment of ZWINT expression in clinical subgroups, immune infiltration, and prognostic relevance using the R program. Search Tool for Recurring Instances of Neighbouring Genes (STRING) tool was applied to construct a ZWINT co-expression network and the potential biological functions involved in differentially expressed genes (DEGs) were investigated by enrichment analysis. ZWINT was upregulated in prostate cancer tissues and showed to be significantly associated with T stage, N stages, Gleason score (GS), and prognosis of prostate cancer patients. Functional enrichment analysis revealed that ZWINT-related genes were mainly related to cell cycle, meiosis, myogenic fiber synthesis, and muscle contraction. In addition, High-expression of ZWINT may have possessed immunosuppressive effects through adverse regulation of several immune cells and factors. ZWINT is overexpressed in prostate cancer and correlated with immune infiltration, which is expected to be a potential biomarker for PCa prognosis.
前列腺癌(PCa)是全球男性群体中最常见的上皮恶性肿瘤,是男性癌症相关死亡的第五大原因。ZW10相互作用子(ZWINT)参与染色体分离过程,该过程与几种肿瘤细胞的形成有关。然而,其在PCa中的功能尚不清楚。因此,我们的目的是探索ZWINT在前列腺癌进展中的潜在机制。我们从加州大学圣克鲁兹分校(UCSC)数据库的癌症基因组图谱计划(TCGA)中获得RNA-seq和临床数据。使用R程序评估ZWINT在临床亚组、免疫浸润和预后相关性中的表达。利用Search Tool for Recurring Instances of nearby Genes (STRING)工具构建ZWINT共表达网络,并通过富集分析研究差异表达基因(differential expression Genes, DEGs)可能涉及的生物学功能。ZWINT在前列腺癌组织中表达上调,与前列腺癌患者的T分期、N分期、Gleason评分(GS)及预后显著相关。功能富集分析显示,zwint相关基因主要与细胞周期、减数分裂、肌原纤维合成和肌肉收缩有关。此外,ZWINT的高表达可能通过对多种免疫细胞和因子的不良调控而具有免疫抑制作用。ZWINT在前列腺癌中过表达,且与免疫浸润相关,有望成为前列腺癌预后的潜在生物标志物。
{"title":"Upregulation of the ZWINT expression correlates with prostate cancer progression and immune infiltration","authors":"","doi":"10.22514/jomh.2023.085","DOIUrl":"https://doi.org/10.22514/jomh.2023.085","url":null,"abstract":"Prostate cancer (PCa), the most prevalent epithelial malignant neoplasm in the male group globally, is the fifth largest cause of cancer-related death in males. ZW10 Interactor (ZWINT) is involved in the chromosome segregation process, which is linked to the formation of several tumor cells. However, its function in PCa remains unknown. Therefore, our aim was to explore the potential mechanisms of ZWINT in PCa progression. We obtained RNA-seq as well as clinical data from The Cancer Genome Atlas Program (TCGA), University of California Santa Cruz (UCSC) database. Assessment of ZWINT expression in clinical subgroups, immune infiltration, and prognostic relevance using the R program. Search Tool for Recurring Instances of Neighbouring Genes (STRING) tool was applied to construct a ZWINT co-expression network and the potential biological functions involved in differentially expressed genes (DEGs) were investigated by enrichment analysis. ZWINT was upregulated in prostate cancer tissues and showed to be significantly associated with T stage, N stages, Gleason score (GS), and prognosis of prostate cancer patients. Functional enrichment analysis revealed that ZWINT-related genes were mainly related to cell cycle, meiosis, myogenic fiber synthesis, and muscle contraction. In addition, High-expression of ZWINT may have possessed immunosuppressive effects through adverse regulation of several immune cells and factors. ZWINT is overexpressed in prostate cancer and correlated with immune infiltration, which is expected to be a potential biomarker for PCa prognosis.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135801068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Are male soccer players accumulating sufficient load across varying microcycle structures? Examining the load, wellness and training/match ratios of a professional team 男性足球运动员是否在不同的微循环结构中积累了足够的载荷?考察一支专业队伍的负荷、健康状况和训练/比赛比率
4区 医学 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.22514/jomh.2023.083
Professional soccer involves varying numbers of training sessions and matches each week, which can influence load distribution. Understanding the exact distribution may allow appropriate load periodisation and planning for players. Thus, this study aimed to (i) compare accumulated load and wellness between weeks with different numbers of training sessions and (ii) compare training/match ratio (TMr) of external and internal load between weeks with different numbers of training sessions. Ten players with a minimum of 45 minutes of weekly match-play were analysed over 16 weeks. The microcycle structures consisted of three (3dW), four (4dW), five (5dW) and six (6dW) training sessions plus match-day per week. The following measures were used for analysis: duration, fatigue, quality of sleep, muscle soreness, stress, mood, rating of perceived exertion (RPE), session-RPE (s-RPE), high-speed running distance (HSR), sprint distance (SPD), number of accelerations (ACC) and decelerations (DEC). Accumulated wellness/load were calculated by adding all training and match sessions, while TMr was calculated by dividing accumulated load by match data. The main results showed that accumulated wellness and load were significantly different, with moderate to very large effect sizes, except regarding mood, duration, s-RPE, SPD during 5dW vs. 6dW and s-RPE, HSR, SPD, ACC and DEC during 3dW vs. 4dW (all p > 0.05). Moreover, 6dW was significantly higher than 4dW regarding TMr of duration (p < 0.05, moderate effect size), RPE, HSR and SPD (all p < 0.05 with very large effect sizes) and for 3dW of HSR and ACC (p < 0.05 with very large effect sizes). This study showed that 5dW and 6dW had higher training measures than 3dW or 4dW. Additionally, higher wellness was presented in the microcycles with higher training frequencies. These findings suggest that physical load and wellness were not adjusted according to the number of training sessions within a microcycle.
职业足球每周包括不同数量的训练和比赛,这可能会影响负荷分配。了解准确的分布可以为玩家提供适当的加载周期和计划。因此,本研究旨在(i)比较不同训练次数周之间的累积负荷和健康状况;(ii)比较不同训练次数周之间的内外负荷训练/匹配比(TMr)。10名每周比赛至少45分钟的球员在16周的时间里进行了分析。微周期结构包括每周3次(3dW)、4次(4dW)、5次(5dW)和6次(6dW)训练以及比赛日。采用以下测量方法进行分析:持续时间、疲劳程度、睡眠质量、肌肉酸痛、压力、情绪、感知消耗等级(RPE)、会话-RPE (s-RPE)、高速跑距离(HSR)、冲刺距离(SPD)、加速次数(ACC)和减速次数(DEC)。累积健康/负荷通过将所有训练和比赛次数相加来计算,而TMr通过将累积负荷除以比赛数据来计算。主要结果显示,除了5dW与6dW期间的情绪、持续时间、s-RPE、SPD以及3dW与4dW期间的s-RPE、HSR、SPD、ACC和DEC(均p >0.05)。此外,在持续时间方面,6dW显著高于4dW (p <0.05,中等效应量)、RPE、HSR和SPD(均p <0.05,效应量非常大),以及HSR和ACC的3dW (p <0.05,效应量非常大)。本研究表明5dW和6dW比3dW和4dW有更高的训练措施。此外,训练频率越高的微循环,健康状况越好。这些发现表明,身体负荷和健康状况并没有根据一个微周期内的训练次数进行调整。
{"title":"Are male soccer players accumulating sufficient load across varying microcycle structures? Examining the load, wellness and training/match ratios of a professional team","authors":"","doi":"10.22514/jomh.2023.083","DOIUrl":"https://doi.org/10.22514/jomh.2023.083","url":null,"abstract":"Professional soccer involves varying numbers of training sessions and matches each week, which can influence load distribution. Understanding the exact distribution may allow appropriate load periodisation and planning for players. Thus, this study aimed to (i) compare accumulated load and wellness between weeks with different numbers of training sessions and (ii) compare training/match ratio (TMr) of external and internal load between weeks with different numbers of training sessions. Ten players with a minimum of 45 minutes of weekly match-play were analysed over 16 weeks. The microcycle structures consisted of three (3dW), four (4dW), five (5dW) and six (6dW) training sessions plus match-day per week. The following measures were used for analysis: duration, fatigue, quality of sleep, muscle soreness, stress, mood, rating of perceived exertion (RPE), session-RPE (s-RPE), high-speed running distance (HSR), sprint distance (SPD), number of accelerations (ACC) and decelerations (DEC). Accumulated wellness/load were calculated by adding all training and match sessions, while TMr was calculated by dividing accumulated load by match data. The main results showed that accumulated wellness and load were significantly different, with moderate to very large effect sizes, except regarding mood, duration, s-RPE, SPD during 5dW vs. 6dW and s-RPE, HSR, SPD, ACC and DEC during 3dW vs. 4dW (all p > 0.05). Moreover, 6dW was significantly higher than 4dW regarding TMr of duration (p < 0.05, moderate effect size), RPE, HSR and SPD (all p < 0.05 with very large effect sizes) and for 3dW of HSR and ACC (p < 0.05 with very large effect sizes). This study showed that 5dW and 6dW had higher training measures than 3dW or 4dW. Additionally, higher wellness was presented in the microcycles with higher training frequencies. These findings suggest that physical load and wellness were not adjusted according to the number of training sessions within a microcycle.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135801069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transurethral resection of ejaculatory ducts (TURED) for the management of ejaculatory duct obstruction: a Saudi cohort 经尿道射精管切除术(ture)治疗射精管阻塞:沙特队列
4区 医学 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.22514/jomh.2023.086
This retrospective study aimed to investigate the clinical characteristics, changes in semen parameters, and outcomes of adult patients with ejaculatory duct obstruction (EDO) who underwent transurethral resection of ejaculatory ducts (TURED). The study included 25 patients diagnosed with EDO who underwent TURED at King Faisal Specialist Hospital & Research Center in Saudi Arabia between January 2015 and December 2021. The results showed that 68% of the patients had complete ED obstruction, while 32% had partial obstruction. Primary infertility was reported in 68%of the patients, with 4% experiencing secondary infertility. The analysis revealed a significant increase in semen volume greater than 0.6 after TURED, while there was a significant decrease in volumes ranging from 0.1 to 0.3 and from 0.4 to 0.6. Patients with partial ED obstruction demonstrated a significant improvement in semen parameters compared to those with complete ED obstruction. The findings suggest that TURED is a safe and effective treatment option for EDO, leading to significant improvements in semen parameters and potentially resulting in spontaneous pregnancy. However, further research is needed to identify specific patient subgroups that may benefit the most from TURED. While magnetic resonance imaging (MRI) with an endorectal coil has been proposed for more detailed evaluation, transrectal ultrasound (TRUS) has been suggested as the standard examination technique.
本回顾性研究旨在探讨射精管梗阻(EDO)成人患者经尿道射精管切除术(TURED)的临床特点、精液参数的变化和预后。该研究包括25名确诊为EDO的患者,他们在费萨尔国王专科医院(King Faisal Specialist Hospital)接受了化疗。2015年1月至2021年12月在沙特阿拉伯的研究中心。结果显示,68%的患者为完全性ED梗阻,32%的患者为部分梗阻。68%的患者报告原发性不孕,4%的患者报告继发性不孕。分析结果显示,在治疗后,精液体积显著增加,大于0.6,而在0.1 - 0.3和0.4 - 0.6的范围内,精液体积显著减少。部分ED梗阻患者与完全ED梗阻患者相比,精液参数有显著改善。研究结果表明,对于EDO患者来说,tued是一种安全有效的治疗选择,可显著改善精液参数,并有可能导致自然妊娠。然而,需要进一步的研究来确定可能从TURED获益最多的特定患者亚组。虽然磁共振成像(MRI)与直肠内线圈已被建议进行更详细的评估,经直肠超声(TRUS)已被建议作为标准的检查技术。
{"title":"Transurethral resection of ejaculatory ducts (TURED) for the management of ejaculatory duct obstruction: a Saudi cohort","authors":"","doi":"10.22514/jomh.2023.086","DOIUrl":"https://doi.org/10.22514/jomh.2023.086","url":null,"abstract":"This retrospective study aimed to investigate the clinical characteristics, changes in semen parameters, and outcomes of adult patients with ejaculatory duct obstruction (EDO) who underwent transurethral resection of ejaculatory ducts (TURED). The study included 25 patients diagnosed with EDO who underwent TURED at King Faisal Specialist Hospital &amp; Research Center in Saudi Arabia between January 2015 and December 2021. The results showed that 68% of the patients had complete ED obstruction, while 32% had partial obstruction. Primary infertility was reported in 68%of the patients, with 4% experiencing secondary infertility. The analysis revealed a significant increase in semen volume greater than 0.6 after TURED, while there was a significant decrease in volumes ranging from 0.1 to 0.3 and from 0.4 to 0.6. Patients with partial ED obstruction demonstrated a significant improvement in semen parameters compared to those with complete ED obstruction. The findings suggest that TURED is a safe and effective treatment option for EDO, leading to significant improvements in semen parameters and potentially resulting in spontaneous pregnancy. However, further research is needed to identify specific patient subgroups that may benefit the most from TURED. While magnetic resonance imaging (MRI) with an endorectal coil has been proposed for more detailed evaluation, transrectal ultrasound (TRUS) has been suggested as the standard examination technique.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"282 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135801332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Small-sided game-related physical performance is not influenced by the sprint and power performance of youth male soccer players 青少年男子足球运动员的小面比赛相关体能表现不受短跑和力量表现的影响
4区 医学 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.22514/jomh.2023.074
The aim of this study was to analyse the effects of sprint and power performance on physical fitness and small-sided game-related physical performance in youth male soccer players, using a median split analysis to separate faster and slower players, and powerful and weaker ones. Thirty youth male soccer players (age = 16.9 ± 1.4 years; height = 174.1 ± 7.1 cm; body mass = 63.1 ± 7.9 kg; % body fat = 15.5 ± 3.2) completed the following physical tests: 40 m linear sprint test, repeated sprint ability (RSA) test, countermovement jump (CMJ), horizontal jump (HJ) and a half-squat (HS) power test. In addition, players completed a 4 vs. 4 with goalkeepers small-sided game while external loads were recorded. According to their sprint and HS power performance, players were divided into fast and slow, and powerful and weak. Faster players performed better in 5 m sprint (p = 0.004, Effect Size (ES) = −1.158), 10 m sprint (p < 0.001, ES =−1.722), 40 m sprint (p < 0.001, ES = −3.268), RSAbest (p < 0.001, ES = −2.415), RSAtotal (p < 0.001, ES = −2.785), CMJ height (p = 0.032, ES = 0.823) and HJ distance (p < 0.001, ES = 1.589), but no significant differences (p > 0.05) were found in external loads during small-side games (SSG). In addition, no significant differences (p > 0.05) were observed between powerful and weaker players in the fitness tests and SSG-related physical performance. These results highlight the importance of grouping youth soccer players by their sprinting capacity to design specific and individualized training strategies and suggest that SSG-related physical performance is not influenced by their sprint or power performance.
本研究的目的是分析冲刺和力量表现对青少年男子足球运动员身体素质和小边比赛相关身体表现的影响,使用中位数分裂分析来区分快球员和慢球员,强球员和弱球员。30名青少年男子足球运动员(年龄= 16.9±1.4岁,身高= 174.1±7.1 cm,体重= 63.1±7.9 kg,体脂% = 15.5±3.2)完成了40米直线冲刺测试、重复冲刺能力(RSA)测试、反向跳跃(CMJ)、水平跳跃(HJ)和半深蹲(HS)力量测试。此外,在记录外部负载的同时,玩家完成了与守门员的4对4小边游戏。根据选手的冲刺和HS功率表现,将选手分为快、慢、强、弱。速度越快的运动员在5米冲刺(p = 0.004,效应量(ES) = - 1.158)和10米冲刺(p <0.001, ES = - 1.722), 40米冲刺(p <0.001, ES = - 3.268), RSAbest (p <0.001, ES = - 2.415), rsattotal (p <0.001, ES =−2.785),CMJ高度(p = 0.032, ES = 0.823)和HJ距离(p <0.001, ES = 1.589),但差异无统计学意义(p >0.05),在小侧游戏(SSG)期间的外部负载中发现。此外,无显著差异(p >在体能测试和ssg相关体能表现方面,强弱选手之间存在显著性差异(0.05)。这些结果强调了根据青少年足球运动员的冲刺能力进行分组以设计具体和个性化的训练策略的重要性,并表明他们的冲刺或力量表现不影响ssg相关的身体表现。
{"title":"Small-sided game-related physical performance is not influenced by the sprint and power performance of youth male soccer players","authors":"","doi":"10.22514/jomh.2023.074","DOIUrl":"https://doi.org/10.22514/jomh.2023.074","url":null,"abstract":"The aim of this study was to analyse the effects of sprint and power performance on physical fitness and small-sided game-related physical performance in youth male soccer players, using a median split analysis to separate faster and slower players, and powerful and weaker ones. Thirty youth male soccer players (age = 16.9 ± 1.4 years; height = 174.1 ± 7.1 cm; body mass = 63.1 ± 7.9 kg; % body fat = 15.5 ± 3.2) completed the following physical tests: 40 m linear sprint test, repeated sprint ability (RSA) test, countermovement jump (CMJ), horizontal jump (HJ) and a half-squat (HS) power test. In addition, players completed a 4 vs. 4 with goalkeepers small-sided game while external loads were recorded. According to their sprint and HS power performance, players were divided into fast and slow, and powerful and weak. Faster players performed better in 5 m sprint (p = 0.004, Effect Size (ES) = −1.158), 10 m sprint (p < 0.001, ES =−1.722), 40 m sprint (p < 0.001, ES = −3.268), RSAbest (p < 0.001, ES = −2.415), RSAtotal (p < 0.001, ES = −2.785), CMJ height (p = 0.032, ES = 0.823) and HJ distance (p < 0.001, ES = 1.589), but no significant differences (p > 0.05) were found in external loads during small-side games (SSG). In addition, no significant differences (p > 0.05) were observed between powerful and weaker players in the fitness tests and SSG-related physical performance. These results highlight the importance of grouping youth soccer players by their sprinting capacity to design specific and individualized training strategies and suggest that SSG-related physical performance is not influenced by their sprint or power performance.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"170 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135058792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HPV vaccination among gay, bisexual and other men who have sex with men in Canada's three largest cities: a person-centred approach 在加拿大三个最大城市的男同性恋者、双性恋者和其他男男性行为者中接种HPV疫苗:以人为本的方法
4区 医学 Q4 Medicine Pub Date : 2023-01-01 DOI: 10.22514/10.22514/jomh.2023.097
Starting in 2015, many Canadian provinces and territories introduced publicly-funded human papillomavirus (HPV) vaccination programs targeted to gay, bisexual and other men who have sex with men (GBM) 9–26 years old. Using baseline data from the Engage study, a sexual health study of GBM from three Canadian cities, we explored how social and programmatic factors intersect and affect stages of HPV vaccination (Stage 1: unaware of HPV vaccine, Stage 2: undecided/unwilling to get vaccinated, Stage 3: willing to get vaccinated, Stage 4: vaccinated with at least one dose). First, by city, we created subgroups of GBM ≤26 years old (N Vancouver = 178; Toronto = 123; Montreal = 249) using latent class analysis. Next, by latent class, we estimated the probability of being in the four HPV vaccination stages using the Bolck, Croon and Hagenaar method. Latent class membership was associated with HPV vaccination stage in Vancouver (p = 0.003) and Montreal (p = 0.048) but not Toronto (p = 0.642). In Vancouver and Montreal, membership in the “no barriers” latent class had the highest probability of vaccination (56–58%). In Vancouver, the “racialized, GBM privacy, immigration and healthcare access barriers” class had a 75% probability of being vaccine unaware. In Montreal, the “immigration and past vaccines barriers” and “socio-economic, GBM privacy and healthcare access barriers” classes had the highest probabilities of being vaccine unaware (43% and 46%) and of being undecided or unwilling to get vaccinated (40% and 25%). In conclusion, our person-centred findings suggest tailored interventions by locale may help to increase HPV vaccine uptake among GBM in Canada’s three largest cities.
从2015年开始,加拿大许多省份和地区引入了公共资助的人类乳头瘤病毒(HPV)疫苗接种项目,目标人群是9-26岁的男同性恋、双性恋和其他男男性行为者(GBM)。使用Engage研究(一项来自加拿大三个城市的GBM性健康研究)的基线数据,我们探讨了社会和规划因素如何交叉并影响HPV疫苗接种阶段(第一阶段:不知道HPV疫苗,第二阶段:未决定/不愿接种疫苗,第三阶段:愿意接种疫苗,第四阶段:至少接种一剂疫苗)。首先,按城市划分,我们使用潜在类分析创建GBM≤26岁的亚组(温哥华= 178;多伦多= 123;蒙特利尔= 249)。接下来,根据潜在类别,我们使用Bolck, Croon和Hagenaar方法估计处于四个HPV疫苗接种阶段的概率。温哥华(p = 0.003)和蒙特利尔(p = 0.048)的潜在类别成员与HPV疫苗接种阶段相关,但多伦多(p = 0.642)无关。在温哥华和蒙特利尔,“无障碍”潜在类别的成员接种疫苗的概率最高(56-58%)。在温哥华,“种族化、GBM隐私、移民和医疗保健准入障碍”阶层有75%的可能性不知道疫苗。在蒙特利尔,“移民和过去的疫苗障碍”和“社会经济、性别歧视隐私和医疗保健准入障碍”类别的人不知道疫苗的概率最高(43%和46%),不决定或不愿接种疫苗的概率最高(40%和25%)。总之,我们以人为中心的研究结果表明,根据地区进行量身定制的干预可能有助于增加加拿大三个最大城市GBM中HPV疫苗的吸收率。
{"title":"HPV vaccination among gay, bisexual and other men who have sex with men in Canada's three largest cities: a person-centred approach","authors":"","doi":"10.22514/10.22514/jomh.2023.097","DOIUrl":"https://doi.org/10.22514/10.22514/jomh.2023.097","url":null,"abstract":"Starting in 2015, many Canadian provinces and territories introduced publicly-funded human papillomavirus (HPV) vaccination programs targeted to gay, bisexual and other men who have sex with men (GBM) 9–26 years old. Using baseline data from the Engage study, a sexual health study of GBM from three Canadian cities, we explored how social and programmatic factors intersect and affect stages of HPV vaccination (Stage 1: unaware of HPV vaccine, Stage 2: undecided/unwilling to get vaccinated, Stage 3: willing to get vaccinated, Stage 4: vaccinated with at least one dose). First, by city, we created subgroups of GBM ≤26 years old (N Vancouver = 178; Toronto = 123; Montreal = 249) using latent class analysis. Next, by latent class, we estimated the probability of being in the four HPV vaccination stages using the Bolck, Croon and Hagenaar method. Latent class membership was associated with HPV vaccination stage in Vancouver (p = 0.003) and Montreal (p = 0.048) but not Toronto (p = 0.642). In Vancouver and Montreal, membership in the “no barriers” latent class had the highest probability of vaccination (56–58%). In Vancouver, the “racialized, GBM privacy, immigration and healthcare access barriers” class had a 75% probability of being vaccine unaware. In Montreal, the “immigration and past vaccines barriers” and “socio-economic, GBM privacy and healthcare access barriers” classes had the highest probabilities of being vaccine unaware (43% and 46%) and of being undecided or unwilling to get vaccinated (40% and 25%). In conclusion, our person-centred findings suggest tailored interventions by locale may help to increase HPV vaccine uptake among GBM in Canada’s three largest cities.","PeriodicalId":16360,"journal":{"name":"Journal of Men's Health","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135260978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Men's Health
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1