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Long-Term Postoperative Recurrence Rates and Fertility Outcomes After Endometrioma CO2-Laser Vaporization: A Five-Year Follow-Up Experience 子宫内膜异位症二氧化碳激光汽化术后长期复发率和生育率:5 年随访经验。
IF 3.5 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-01 DOI: 10.1016/j.jmig.2024.09.367
Stefano M. Ferrari MD, Carolina Dolci MD, Iacopo Tandoi MD, Matteo Schimberni MD, Ludovica Bartiromo MD, Noemi Salmeri MD, Sara D'Alessandro MD, Giulia Carnemolla MD, Giorgia Grisafi MD, Massimo Candiani MD

Study Objective

Although cystectomy remains the gold standard for the surgical treatments of endometriomas, concerns about the negative effect on ovarian reserve are rising. Laser-CO2 vaporization of endometriomas has shown encouraging data on ovarian reserve preservation, postoperative pregnancy rates, and recurrence. The aim of this study was to assess postoperative recurrence rate and pregnancy rate in patients with endometriomas managed by CO2 fiber laser vaporization after at least 5 years following surgery.

Design

Retrospective study.

Setting

Italian tertiary center from October 2023 to February 2024.

Patients

We included women aged >18 years who underwent laparoscopic CO2 fiber laser vaporization for endometriomas. Age ≥40 years, previous ovarian surgery, previous salpingectomy or hysterectomy, negative histologic finding for endometriosis, or any findings of malignancy at histology were exclusion criteria.

Intervention

Ovarian endometriomas were vaporized through laparoscopic CO2 fiber laser. After surgery, patients were included in a surveillance program with periodic clinical follow-ups.

Measurements and Main Results

Seventy-eight patients were included. The mean age was 33.2 ± 4.6 years, the basal anti-Müllerian hormone was 2.7 ± 1.9 ng/mL, and the median diameter of the endometriomas was 4 (3–5) cm. The median duration of follow-up was 72.5 months (67–84.5). After surgery, 65.5% (n = 36) of women with reproductive desire achieved a pregnancy, 55.6% spontaneously, and 44.4% through Assisted Reproduction Techniques, with a mean time to pregnancy of 17.7 ± 18.1 months. A Kaplan-Meier curve for the 7 patients who experienced an ipsilateral recurrence showed that the median time to recurrence was 26 months and the estimated rate of disease-free patients was 91.03% at 100 months (95% confidence interval 82.10%–95.62%).

Conclusion

CO2 fiber laser vaporization is an effective and safe surgical treatment of ovarian endometriomas, combining the advantage of being an ovarian tissue-sparing technique with long-term postoperative recurrence rate comparable with that described in literature for the cystectomy.
研究目的尽管子宫内膜异位症手术治疗的金标准仍是膀胱切除术,但人们对其对卵巢储备功能的负面影响的担忧却在不断增加。子宫内膜异位症激光二氧化碳气化术在卵巢储备保留、术后妊娠率和复发率方面显示出令人鼓舞的数据。本研究旨在评估通过二氧化碳光纤激光气化术治疗的子宫内膜异位症患者在术后至少5年后的术后复发率和妊娠率:设计:回顾性研究:研究时间:2023年10月至2024年2月,地点:意大利三级医疗中心:我们纳入了年龄大于 18 岁、因子宫内膜异位症接受腹腔镜 CO2 光纤激光气化术的女性。年龄≥40岁、既往接受过卵巢手术、既往接受过输卵管切除术或子宫切除术、子宫内膜异位症组织学检查阴性或组织学检查发现任何恶性肿瘤均为排除标准:干预措施:通过腹腔镜二氧化碳光纤激光对卵巢子宫内膜异位症进行气化。干预措施:通过腹腔镜二氧化碳光纤激光对卵巢子宫内膜异位症进行气化,术后对患者进行定期临床随访:共纳入 78 例患者。平均年龄为(33.2±4.6)岁,基础 AMH 为(2.7±1.9)纳克/毫升,子宫内膜异位症的中位直径为 4(3-5)厘米。随访时间的中位数为 72.5 个月(67-84.5 个月)。手术后,65.5%(36 人)有生育要求的妇女成功怀孕,其中 55.6% 自然怀孕,44.4% 通过辅助生殖技术怀孕,平均怀孕时间为 17.7±18.1 个月。7例同侧复发患者的卡普兰-梅耶尔曲线显示,复发的中位时间为26个月,100个月时的无病率估计为91.03%(95% CI为82.10%-95.62%):CO2光纤激光汽化术是一种有效、安全的卵巢子宫内膜异位症手术治疗方法,它具有保留卵巢组织的优势,术后长期复发率与文献中描述的膀胱切除术相当。
{"title":"Long-Term Postoperative Recurrence Rates and Fertility Outcomes After Endometrioma CO2-Laser Vaporization: A Five-Year Follow-Up Experience","authors":"Stefano M. Ferrari MD,&nbsp;Carolina Dolci MD,&nbsp;Iacopo Tandoi MD,&nbsp;Matteo Schimberni MD,&nbsp;Ludovica Bartiromo MD,&nbsp;Noemi Salmeri MD,&nbsp;Sara D'Alessandro MD,&nbsp;Giulia Carnemolla MD,&nbsp;Giorgia Grisafi MD,&nbsp;Massimo Candiani MD","doi":"10.1016/j.jmig.2024.09.367","DOIUrl":"10.1016/j.jmig.2024.09.367","url":null,"abstract":"<div><h3>Study Objective</h3><div>Although cystectomy remains the gold standard for the surgical treatments of endometriomas, concerns about the negative effect on ovarian reserve are rising. Laser-CO<sub>2</sub> vaporization of endometriomas has shown encouraging data on ovarian reserve preservation, postoperative pregnancy rates, and recurrence. The aim of this study was to assess postoperative recurrence rate and pregnancy rate in patients with endometriomas managed by CO<sub>2</sub> fiber laser vaporization after at least 5 years following surgery.</div></div><div><h3>Design</h3><div>Retrospective study.</div></div><div><h3>Setting</h3><div>Italian tertiary center from October 2023 to February 2024.</div></div><div><h3>Patients</h3><div>We included women aged &gt;18 years who underwent laparoscopic CO<sub>2</sub> fiber laser vaporization for endometriomas. Age ≥40 years, previous ovarian surgery, previous salpingectomy or hysterectomy, negative histologic finding for endometriosis, or any findings of malignancy at histology were exclusion criteria.</div></div><div><h3>Intervention</h3><div>Ovarian endometriomas were vaporized through laparoscopic CO<sub>2</sub> fiber laser. After surgery, patients were included in a surveillance program with periodic clinical follow-ups.</div></div><div><h3>Measurements and Main Results</h3><div>Seventy-eight patients were included. The mean age was 33.2 ± 4.6 years, the basal anti-Müllerian hormone was 2.7 ± 1.9 ng/mL, and the median diameter of the endometriomas was 4 (3–5) cm. The median duration of follow-up was 72.5 months (67–84.5). After surgery, 65.5% (n = 36) of women with reproductive desire achieved a pregnancy, 55.6% spontaneously, and 44.4% through Assisted Reproduction Techniques, with a mean time to pregnancy of 17.7 ± 18.1 months. A Kaplan-Meier curve for the 7 patients who experienced an ipsilateral recurrence showed that the median time to recurrence was 26 months and the estimated rate of disease-free patients was 91.03% at 100 months (95% confidence interval 82.10%–95.62%).</div></div><div><h3>Conclusion</h3><div>CO<sub>2</sub> fiber laser vaporization is an effective and safe surgical treatment of ovarian endometriomas, combining the advantage of being an ovarian tissue-sparing technique with long-term postoperative recurrence rate comparable with that described in literature for the cystectomy.</div></div>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":"32 2","pages":"Pages 171-176"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Uterine Artery Embolization Due to Intra-Abdominal Bleeding Eight Weeks After Myomectomy 子宫肌瘤剔除术后八周腹腔内出血导致子宫动脉栓塞:子宫肌瘤切除术后子宫动脉栓塞。
IF 3.5 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-01 DOI: 10.1016/j.jmig.2024.08.010
Hale Goksever Celik MD, PhD , Ceyda Buyuker , Boran Aksakal , Faruk Buyru MD
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引用次数: 0
Insights from the Inaugural JMIG Associate Editors.
IF 3.5 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-30 DOI: 10.1016/j.jmig.2025.01.012
Siddhi Mathur, Sadikah Behbehani
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引用次数: 0
Cheek acupuncture reduces postoperative nausea and vomiting in patients undergoing laparoscopic gynecological surgery: A randomized controlled trial.
IF 3.5 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-28 DOI: 10.1016/j.jmig.2025.01.011
Liangrong Wang, Xintong Zou, Linfeng Wu, Zijun Jin, Shuyu Hu, Xianfen Zhu, Xiaoyao Li

Objective: Cheek acupuncture, a recently established microneedle therapy, has been proven to effectively reduce pain, but its potential antiemetic effects remain unconfirmed. Thus, This study aimed to compare the antiemetic efficacy of cheek acupuncture with ondansetron and evaluate the cumulative effect in patients undergoing laparoscopic gynecological surgery.

Design: A single-center randomized controlled trial SETTING: A university teaching hospital.

Patients: A Total of 150 Adult patients who underwent laparoscopic gynecological surgery between July 2023 to December 2023 .

Interventions: Cheek acupuncture, IV ondansetron, or both.

Measurements and main results: The incidence and severity of PONV as well as the postoperative requirement of rescue antiemetic agent were comparable between the cheek acupuncture and ondansetron group in 48 hours postoperatively (p > 0.05), but all of which were significantly reduced in the combination group (p < 0.05). Compared with the ondansetron group, the cheek acupuncture and combination group exhibited reduced pain intensity at 3 and 48 hours postoperatively (p < 0.05). The use of cheek acupuncture was associated with higher satisfaction scores with anesthesia and shorter time of first flatus. Furthermore, no significant differences in other outcomes were found among the three groups (p > 0.05).

Conclusion: Cheek acupuncture had a prominent antiemetic effect in reducing the incidence and severity of PONV in patients undergoing gynecological laparoscopic surgery.

Data availability statement: The data are available at https://data.mendeley.com/datasets/sngg3trx69/1.

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引用次数: 0
Preoperative Medication for Ovarian Endometrioma Reduces Cyst Size and PainBut Not rASRM score.
IF 3.5 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-25 DOI: 10.1016/j.jmig.2025.01.010
Hye-Ji Jung, Sung Eun Kim, Hyeonmyeong Hong, Dong-Yun Lee, DooSeok Choi

Study subject: To investigate the impact of preoperative hormonal medication, including combined oral contraceptives (COCs) or dienogest, on operative findings in ovarian endometrioma surgery.

Design: A single-center, retrospective study.

Setting: Department of Gynecology, Samsung Medical Center, Republic of Korea.

Participants: Among patients who underwent ovarian endometrioma surgery for the first time at Samsung Medical Center between January 2020 and July 2023, those who started hormonal medication at another institution before their initial visit to our center, those with a waiting period of less than three months until the surgery date, and those with an endometrioma size of less than 4cm at the initial visit were excluded. A total 140 remaining patients were included in the study. The patients were divided into two groups: the group that received preoperative hormonal medication (COCs or dienogest) and the group that did not receive medication.

Interventions: To evaluate the impacts of preoperative hormonal medication on ovarian endometrioma patients, the operative findings were compared between the groups.

Results: Of the140 patients, 65 were in the no-medication group and 75 were in the medication group. Except for the median duration of follow-up and age, there were no differences in the baseline characteristics between the two groups. Operative findings were quantified using the revised American Society for Reproductive Medicine (rASRM) score. Although medication significantly reduced the size of the ovarian endometrioma, there were no significant differences in rASRM score between the two groups. However, the medication group experienced significant preoperative pain relief.

Conclusion: Preoperative hormonal medication can reduce the size of ovarian endometriomas but does not significantly affect the overall operative findings. Nevertheless, preoperative medication is helpful in reducing pain in patients before surgery.

研究课题调查术前激素药物(包括复方口服避孕药(COC)或地诺孕酮)对卵巢子宫内膜瘤手术结果的影响:设计:单中心回顾性研究:地点:大韩民国三星医疗中心妇科:在2020年1月至2023年7月期间首次在三星医疗中心接受卵巢子宫内膜瘤手术的患者中,排除了在首次到本中心就诊前已在其他机构开始使用激素药物的患者、手术日期前等待时间少于3个月的患者以及首次就诊时子宫内膜瘤大小小于4厘米的患者。研究共纳入了 140 名剩余患者。患者被分为两组:术前接受激素药物治疗(COCs 或地诺孕酮)组和未接受药物治疗组:干预措施:为评估术前激素药物对卵巢子宫内膜异位症患者的影响,比较两组患者的手术结果:140例患者中,65例为未用药组,75例为用药组。除中位随访时间和年龄外,两组患者的基线特征无差异。手术结果采用修订后的美国生殖医学会(rASRM)评分进行量化。虽然药物治疗能明显缩小卵巢子宫内膜异位症的大小,但两组患者的 rASRM 评分无明显差异。然而,药物治疗组的术前疼痛明显缓解:结论:术前激素药物治疗可缩小卵巢子宫内膜异位症的大小,但对整体手术结果影响不大。不过,术前用药有助于减轻患者术前疼痛。
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引用次数: 0
Time for an education revamp? A nationwide survey of Fellowship in Minimally Invasive Gynecologic Surgery program directors' and fellows' didactics experiences.
IF 3.5 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-25 DOI: 10.1016/j.jmig.2025.01.009
Merima Ruhotina, Colleen Murphy, Elizabeth Rasmussen, Joan Skelly, Masoud Azodi, Shabnam Kashani

Study objective: A desire for curriculum standardization in obstetrics and gynecology residencies has been identified. No prior investigation of educational experiences in Fellowship in Minimally Invasive Gynecologic Surgery (FMIGS) programs has been completed. The purpose of this study was to determine the state of FMIGS didactic education and the perceptions that fellowship directors and fellows have regarding a standardized curriculum.

Design: National survey SETTING: Web-based survey platform PARTICIPANTS: AAGL FMIGS program directors and fellows INTERVENTIONS: N/A RESULTS: A total of 87 out of 151 fellowship directors responded to the survey resulting in a response rate of 57.6%. A total of 58 of 97 fellows responded to the survey with a response rate of 59.8%. When participants were asked if their programs had structured didactic education curriculums, 98.9% of fellowship directors replied yes while only 77.6% of fellows responded yes (p<.001). Approximately 97% fellowship directors reported that structured didactic time is protected from clinical duties. However, only 67.2% of fellows reported that didactic time was protected (p<.001). Participants (71.3% of fellowship directors and 84.5% of fellows) strongly agreed/agreed that their didactic education could be improved. A large majority of participants agreed that all MIGS fellows should learn the same content in their didactics curriculums, that fellows should have access to the same educational resources and that participating in a standardized didactic curriculum would allow for better transition into independent practice.

Conclusion: Fellowship directors and fellows are aligned in the desire for improvement in their current didactic education programs and the need for a centrally located, structured, and standardized fellowship education curriculum.

研究目的:妇产科住院医师培训课程需要标准化。此前尚未完成对妇科微创手术(FMIGS)项目研究员教育经验的调查。本研究的目的是确定微创妇科手术(FMIGS)教学的现状,以及研究金主任和研究员对标准化课程的看法:设计:全国调查设置:基于网络的调查平台 参与者:AAGL FMIGS项目主任和研究员:结果:151 位研究金主任中有 87 位对调查做出了回应,回应率为 57.6%。在 97 名研究员中,共有 58 人回复了调查,回复率为 59.8%。当参与者被问及他们的项目是否有结构化的教学教育课程时,98.9%的研究金主任回答有,而只有77.6%的研究员回答有(P结论:研究员主任和研究员一致希望改善目前的教学教育计划,并需要一个集中、结构化和标准化的研究员教育课程。
{"title":"Time for an education revamp? A nationwide survey of Fellowship in Minimally Invasive Gynecologic Surgery program directors' and fellows' didactics experiences.","authors":"Merima Ruhotina, Colleen Murphy, Elizabeth Rasmussen, Joan Skelly, Masoud Azodi, Shabnam Kashani","doi":"10.1016/j.jmig.2025.01.009","DOIUrl":"https://doi.org/10.1016/j.jmig.2025.01.009","url":null,"abstract":"<p><strong>Study objective: </strong>A desire for curriculum standardization in obstetrics and gynecology residencies has been identified. No prior investigation of educational experiences in Fellowship in Minimally Invasive Gynecologic Surgery (FMIGS) programs has been completed. The purpose of this study was to determine the state of FMIGS didactic education and the perceptions that fellowship directors and fellows have regarding a standardized curriculum.</p><p><strong>Design: </strong>National survey SETTING: Web-based survey platform PARTICIPANTS: AAGL FMIGS program directors and fellows INTERVENTIONS: N/A RESULTS: A total of 87 out of 151 fellowship directors responded to the survey resulting in a response rate of 57.6%. A total of 58 of 97 fellows responded to the survey with a response rate of 59.8%. When participants were asked if their programs had structured didactic education curriculums, 98.9% of fellowship directors replied yes while only 77.6% of fellows responded yes (p<.001). Approximately 97% fellowship directors reported that structured didactic time is protected from clinical duties. However, only 67.2% of fellows reported that didactic time was protected (p<.001). Participants (71.3% of fellowship directors and 84.5% of fellows) strongly agreed/agreed that their didactic education could be improved. A large majority of participants agreed that all MIGS fellows should learn the same content in their didactics curriculums, that fellows should have access to the same educational resources and that participating in a standardized didactic curriculum would allow for better transition into independent practice.</p><p><strong>Conclusion: </strong>Fellowship directors and fellows are aligned in the desire for improvement in their current didactic education programs and the need for a centrally located, structured, and standardized fellowship education curriculum.</p>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Presidential Address Presented at the 53rd AAGL Global Congress in New Orleans on the 17th of November 2024: Look Forward!
IF 3.5 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-21 DOI: 10.1016/j.jmig.2025.01.007
Michel Canis
{"title":"Presidential Address Presented at the 53rd AAGL Global Congress in New Orleans on the 17th of November 2024: Look Forward!","authors":"Michel Canis","doi":"10.1016/j.jmig.2025.01.007","DOIUrl":"10.1016/j.jmig.2025.01.007","url":null,"abstract":"","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vaginal-Assisted NOTES Hysterectomy for Large Uterus Using the da Vinci SP.
IF 3.5 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-20 DOI: 10.1016/j.jmig.2025.01.008
Kiyoshi Kanno, Naofumi Higuchi, Ryo Taniguchi, Masaaki Andou

Objective: Recent advancements of minimally invasive gynecologic surgery have led to the development of transvaginal natural orifice translumenal endoscopic surgery (vNOTES) [1,2]. Robot-assisted vNOTES has also been explored as a method providing accurate and fine surgical procedures with improved ergonomics, visualization, wristed instruments, elimination of the hand tremor [3,4]. The objective of this video is to demonstrate the technical and anatomical highlights of a vaginal-assisted NOTES hysterectomy (VANH) using the da Vinci SP (SP).

Setting: An urban general hospital. Stepwise demonstration of the technique with narrated video footage.

Participants: A 51-year-old woman, para 2 with no previous history of abdominal surgery, who presented with dysmenorrhea and urinary frequency. Magnetic resonance imaging revealed a large uterus with multiple fibroids.

Interventions: The surgical steps are completely identical to conventional laparoscopic or robotic VANH [2,3]. This suggests that conventional laparoscopic skills are highly transferrable to SP. SP offer several advantages, including high-resolution three-dimensional visualization, articulating instruments, and improved dexterity and range of motion. In addition, conventional multi-arm robotic platforms have difficulty docking and adjusting the arm angle for vNOTES, but SP allows easy docking due to its single-arm design [5]. A Gelpoint V-Path is used as the vNOTES platform to hold the SP metal cannula. This cannula contains four channels, allowing the use of three instruments and a camera. The double bipolar method is used since this facilitates precise dissection with minimal thermal spread. The total operative time was 102 minutes. The estimated blood loss was 50ml without any complications. The uterus weighed 970 g. The postoperative course was uneventful.

Conclusion: VANH using SP is technically safe and feasible for benign uterine diseases in selected patients. Maneuverability of articulating instruments used in SP may allow broad expansion of the indication for vNOTES to more challenging cases. VIDEO ABSTRACT.

{"title":"Vaginal-Assisted NOTES Hysterectomy for Large Uterus Using the da Vinci SP.","authors":"Kiyoshi Kanno, Naofumi Higuchi, Ryo Taniguchi, Masaaki Andou","doi":"10.1016/j.jmig.2025.01.008","DOIUrl":"10.1016/j.jmig.2025.01.008","url":null,"abstract":"<p><strong>Objective: </strong>Recent advancements of minimally invasive gynecologic surgery have led to the development of transvaginal natural orifice translumenal endoscopic surgery (vNOTES) [1,2]. Robot-assisted vNOTES has also been explored as a method providing accurate and fine surgical procedures with improved ergonomics, visualization, wristed instruments, elimination of the hand tremor [3,4]. The objective of this video is to demonstrate the technical and anatomical highlights of a vaginal-assisted NOTES hysterectomy (VANH) using the da Vinci SP (SP).</p><p><strong>Setting: </strong>An urban general hospital. Stepwise demonstration of the technique with narrated video footage.</p><p><strong>Participants: </strong>A 51-year-old woman, para 2 with no previous history of abdominal surgery, who presented with dysmenorrhea and urinary frequency. Magnetic resonance imaging revealed a large uterus with multiple fibroids.</p><p><strong>Interventions: </strong>The surgical steps are completely identical to conventional laparoscopic or robotic VANH [2,3]. This suggests that conventional laparoscopic skills are highly transferrable to SP. SP offer several advantages, including high-resolution three-dimensional visualization, articulating instruments, and improved dexterity and range of motion. In addition, conventional multi-arm robotic platforms have difficulty docking and adjusting the arm angle for vNOTES, but SP allows easy docking due to its single-arm design [5]. A Gelpoint V-Path is used as the vNOTES platform to hold the SP metal cannula. This cannula contains four channels, allowing the use of three instruments and a camera. The double bipolar method is used since this facilitates precise dissection with minimal thermal spread. The total operative time was 102 minutes. The estimated blood loss was 50ml without any complications. The uterus weighed 970 g. The postoperative course was uneventful.</p><p><strong>Conclusion: </strong>VANH using SP is technically safe and feasible for benign uterine diseases in selected patients. Maneuverability of articulating instruments used in SP may allow broad expansion of the indication for vNOTES to more challenging cases. VIDEO ABSTRACT.</p>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep endometriosis: beware of the tip of the iceberg. 深层子宫内膜异位症:小心冰山一角。
IF 3.5 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-16 DOI: 10.1016/j.jmig.2025.01.006
Alessia Limena, Maria Sakellariou, Claire Figuier, Michel Canis
{"title":"Deep endometriosis: beware of the tip of the iceberg.","authors":"Alessia Limena, Maria Sakellariou, Claire Figuier, Michel Canis","doi":"10.1016/j.jmig.2025.01.006","DOIUrl":"https://doi.org/10.1016/j.jmig.2025.01.006","url":null,"abstract":"","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Intracervical Terlipressin on Intravasation and Venous Embolization During Transcervical Myomectomy and Endometrium Resection: A Randomized Controlled Study. 宫颈内特利加压素对经宫颈子宫肌瘤切除术和子宫内膜切除术中静脉栓塞的影响:一项随机对照研究。
IF 3.5 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-14 DOI: 10.1016/j.jmig.2024.12.023
Lucilla E Overdijk, Lillian Hesselink, Paul J M van Kesteren, Peter de Haan, Luuk Karskens, Robert Riezebos, Eric J F Franssen, Bart M P Rademaker

Study objective: To investigate whether intracervical injection of terlipressin during hysteroscopic surgery could reduce the amount of intravasation, the incidence and severity of gas embolism, and the COHb levels in the blood.

Design: Randomized double-blind controlled trial.

Setting: Gynecologic surgical unit in a general hospital.

Patients: Patients who were scheduled for transcervical resection of type 1 or type 2 myomas (TCR-M), or for extensive transcervical endometrium resection (TCR-E).

Interventions: Patients were randomized to receive either terlipressin 0.85 mg or placebo injections intracervical at the beginning of the procedure.

Measurements: The amount of intravasation and level of COHb was measured at the end of the procedure. The incidence and severity of gas embolisms was determined during the procedure by transesophageal echocardiography (TEE). Study groups were compared using an Independent Samples T-Test or a Mann-Whitney U test as indicated.

Main results: Forty-four patients were included in this study. No significant differences were found in intravasation volume, venous emboli and post-surgery COHb between study groups. There was a trend towards more severe embolisms (grade IV embolisms: 12 versus 6, p = .08), paradoxical embolisms (4 versus 2, p = .55) and a shorter operation time (mean of 43 versus 36 minutes, p = .09) in patients who received placebo compared to terlipressin.

Conclusion: This study could not demonstrate a clear beneficial effect of intracervical terlipressin administration. However, further research is needed to investigate if terlipressin can reduce operation time, severe embolisms and the need for redo procedures.

研究目的:探讨宫腔镜术中宫颈内注射特利加压素是否能降低宫腔镜术中气体栓塞的发生率和严重程度,降低血中COHb水平。设计:随机双盲对照试验。地点:某综合医院妇科外科。患者:计划经宫颈切除1型或2型肌瘤(TCR-M)或广泛经宫颈子宫内膜切除术(TCR-E)的患者。干预措施:患者在手术开始时随机接受特利加压素0.85 mg或安慰剂注射。测量方法:在手术结束时测量内渗量和COHb水平。在手术过程中通过经食管超声心动图(TEE)确定气体栓塞的发生率和严重程度。如所示,研究组采用独立样本t检验或Mann-Whitney U检验进行比较。主要结果:共纳入44例患者。两组间血管内容积、静脉栓塞和术后COHb均无显著差异。与安慰剂相比,接受特利加压素的患者有更严重的栓塞(IV级栓塞:12例对6例,p = .08)、矛盾栓塞(4例对2例,p = .55)和更短的手术时间(平均43分钟对36分钟,p = .09)的趋势。结论:本研究不能证明宫颈内施用特利加压素有明确的有益效果。然而,特利加压素是否可以减少手术时间、严重栓塞和重做手术的需要,还需要进一步的研究。
{"title":"The Impact of Intracervical Terlipressin on Intravasation and Venous Embolization During Transcervical Myomectomy and Endometrium Resection: A Randomized Controlled Study.","authors":"Lucilla E Overdijk, Lillian Hesselink, Paul J M van Kesteren, Peter de Haan, Luuk Karskens, Robert Riezebos, Eric J F Franssen, Bart M P Rademaker","doi":"10.1016/j.jmig.2024.12.023","DOIUrl":"10.1016/j.jmig.2024.12.023","url":null,"abstract":"<p><strong>Study objective: </strong>To investigate whether intracervical injection of terlipressin during hysteroscopic surgery could reduce the amount of intravasation, the incidence and severity of gas embolism, and the COHb levels in the blood.</p><p><strong>Design: </strong>Randomized double-blind controlled trial.</p><p><strong>Setting: </strong>Gynecologic surgical unit in a general hospital.</p><p><strong>Patients: </strong>Patients who were scheduled for transcervical resection of type 1 or type 2 myomas (TCR-M), or for extensive transcervical endometrium resection (TCR-E).</p><p><strong>Interventions: </strong>Patients were randomized to receive either terlipressin 0.85 mg or placebo injections intracervical at the beginning of the procedure.</p><p><strong>Measurements: </strong>The amount of intravasation and level of COHb was measured at the end of the procedure. The incidence and severity of gas embolisms was determined during the procedure by transesophageal echocardiography (TEE). Study groups were compared using an Independent Samples T-Test or a Mann-Whitney U test as indicated.</p><p><strong>Main results: </strong>Forty-four patients were included in this study. No significant differences were found in intravasation volume, venous emboli and post-surgery COHb between study groups. There was a trend towards more severe embolisms (grade IV embolisms: 12 versus 6, p = .08), paradoxical embolisms (4 versus 2, p = .55) and a shorter operation time (mean of 43 versus 36 minutes, p = .09) in patients who received placebo compared to terlipressin.</p><p><strong>Conclusion: </strong>This study could not demonstrate a clear beneficial effect of intracervical terlipressin administration. However, further research is needed to investigate if terlipressin can reduce operation time, severe embolisms and the need for redo procedures.</p>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of minimally invasive gynecology
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