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Laparoscopic Davydov Neovagina Creation in Mayer-Rokitansky-Küster-Hauser Syndrome with Pancake Kidney and a Solitary Ureter Using Dual Indocyanine Green Fluorescence Guidance. 双吲哚菁绿色荧光引导下腹腔镜Davydov新阴道形成术治疗伴有烧饼肾和孤立输尿管的mayer - rokitansky - k<s:1> ster- hauser综合征。
IF 3.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-07 DOI: 10.1016/j.jmig.2026.02.043
Marie Josee Salem, Maria Abi Akl, Zaki Sleiman

Objective: To demonstrate a novel dual indocyanine green (ICG) fluorescence-guided laparoscopic Davydov procedure for neovagina creation in a patient with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome and a pancake kidney with a solitary ureter.

Setting: Tertiary referral center.

Participants: A 24-year-old woman with MRKH syndrome and a right-sided pancake kidney with a single ureter, presenting for definitive surgical management.

Interventions: Total laparoscopic Davydov neovagina creation was performed with dual fluorescence guidance. Prophylactic intravenous cefazolin (2 g) was administered at induction in accordance with institutional guidelines. An ICG-soaked rectal pad was positioned to delineate the rectal boundary during rectovaginal tunnel development under near-infrared imaging. Cystoscopy confirmed solitary ureteral anatomy, followed by selective ureteral catheterization and intraluminal ICG instillation to enable continuous real-time visualization during peritoneal mobilization and suturing. The neovaginal pouch was constructed using mobilized peritoneum circumferentially sutured to the introitus with extracorporeal knot-tying, followed by standardized postoperative stenting and dilation.

Conclusion: Dual-structure ICG fluorescence guidance represents an innovative and reproducible adjunct for laparoscopic Davydov neovagina creation. Simultaneous visualization of the rectum and a solitary ureter in the setting of complex renal fusion anomalies enhances anatomic precision and may improve surgical safety during technically demanding MRKH reconstructions.

目的:介绍一种新的双吲哚青绿(ICG)荧光引导下腹腔镜Davydov手术治疗mayer - rokitansky - k ster- hauser (MRKH)综合征和单侧输尿管薄饼肾患者的新阴道形成。单位:三级转诊中心。参与者:一名24岁女性,MRKH综合征,右侧煎饼肾伴单输尿管,提出明确的手术治疗。干预措施:在双荧光引导下进行全腹腔镜Davydov阴道创建。根据机构指南,在诱导时预防性静脉注射头孢唑林(2g)。在近红外成像下,放置icg浸泡的直肠垫来划定直肠阴道隧道发育过程中的直肠边界。膀胱镜检查证实单独输尿管解剖,随后选择性输尿管置管和腔内ICG滴注,以便在腹膜动员和缝合期间连续实时可视化。将游离腹膜经体外打结环缝于阴道开口处,然后进行标准化的术后支架置入和扩张,构建新阴道袋。结论:双结构ICG荧光引导是一种创新的、可重复的腹腔镜Davydov阴道创造辅助手段。在复杂肾融合异常的情况下,直肠和单独输尿管的同时可视化可以提高解剖精度,并可以提高技术要求高的MRKH重建的手术安全性。
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引用次数: 0
Non-invasive blood-based detection of endometriosis can improve standard-of-care by facilitating early diagnosis and clinical management among symptomatic women. 子宫内膜异位症的无创血液检测可以通过促进症状妇女的早期诊断和临床管理来提高护理标准。
IF 3.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-04 DOI: 10.1016/j.jmig.2026.02.042
Wing Hing Wong, Yanqin Yu, Yao Hu, Yirong Shen, Jipeng Chen, Kayla Jarvis, Nicholas Sanford, Kayla A Knudson, Richard Gersh, Charmaine Yisha Ye, Brittney Bastow, Payam Katebi Kashi, Matthew Palmer, Getnet Gedefaw Azeze, Ronald Chi Chiu Wang, James Segars, Farideh Z Bischoff

Study objective: To develop and validate a non-invasive, blood-based diagnostic assay for endometriosis that performs accurately across menstrual cycl phases and complements existing imaging modalities.

Design: Multi-center case-control study with machine learning classification and independent cohort validation.

Setting: Clinical and search settings involving symptomatic women evaluated for suspected endometriosis.

Patients: A total of 298 reproductive-age women were included. The training cohort comprised 218 participants (137 endometriosis-positive and 81 controls). A modest, independent and retrospective validation cohort included 80 participants (40 endometriosis-positive and 40 controls).

Interventions: Peripheral blood sampling with quantification of three microRNAs via qPCR, three protein biomarkers, one steroid hormone using immunoassay, as well as the participant's age and body mass index. Biomarker data were integrated using a random forest machine learning model to classify disease status.

Measurements and main results: In the independent validation cohort, the assay achieved an area under the curve (AUC) of 0.944, sensitivity of 0.80, and specificity of 0.975. Subgroup analysis by menstrual cycle phase demonstrated consistent performance: proliferative-phase samples achieved an AUC of 0.935, sensitivity of 0.767, and specificity of 0.962, while secretory-phase samples achieved an AUC of 0.993, sensitivity of 0.90, and specificity of 1.00. Compared with transvaginal ultrasound and/or MRI, the blood-based assay identified 61.5% histologically confirmed endometriosis cases that were missed by the imaging modalities.

Conclusion: A minimally invasive, multi-omic blood-based assay integrating molecular biomarkers with machine learning can accurately detect endometriosis across menstrual cycle phases and provides complementary diagnostic values. This approach has the potential to improve early detection, and guide timely clinical intervention. A prospective validation is ongoing in geographically and ethnically diverse populations to further assess its broad clinical utility.

研究目的:开发并验证一种无创、基于血液的子宫内膜异位症诊断方法,该方法可以准确地在月经周期各阶段进行诊断,并补充现有的成像方式。设计:采用机器学习分类和独立队列验证的多中心病例对照研究。设置:临床和搜索设置涉及有症状的妇女评估疑似子宫内膜异位症。患者:共纳入298名育龄妇女。培训队列包括218名参与者(137名子宫内膜异位症阳性患者和81名对照组)。一个适度的、独立的、回顾性的验证队列包括80名参与者(40名子宫内膜异位症阳性患者和40名对照组)。干预措施:外周血采样,通过qPCR量化三种microrna,三种蛋白质生物标志物,一种类固醇激素使用免疫测定,以及参与者的年龄和体重指数。使用随机森林机器学习模型整合生物标志物数据以分类疾病状态。测量结果和主要结果:在独立验证队列中,该方法的曲线下面积(AUC)为0.944,灵敏度为0.80,特异性为0.975。月经期亚组分析结果一致:增生期样品AUC为0.935,敏感性为0.767,特异性为0.962;分泌期样品AUC为0.993,敏感性为0.90,特异性为1.00。与经阴道超声和/或MRI相比,基于血液的检测确定了61.5%的组织学证实的子宫内膜异位症,这些病例被影像学检查遗漏了。结论:一种结合分子生物标志物和机器学习的微创、多组血液检测方法可以准确地检测出月经周期各阶段的子宫内膜异位症,并提供补充诊断价值。这种方法有可能提高早期发现,并指导及时的临床干预。一项前瞻性验证正在地域和种族不同的人群中进行,以进一步评估其广泛的临床应用。
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引用次数: 0
Evaluation of the Effect of Hand Size on Forearm Muscle Activity While Using Laparoscopic Instruments 评估使用腹腔镜器械时手的大小对前臂肌肉活动的影响。
IF 3.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2025-12-05 DOI: 10.1016/j.jmig.2025.12.001
Emily Olig MD , Matthew Buras MS , Sara Wilson PhD , Nandita Keole MD , Johnny Yi MD

Objective

Percent maximum voluntary contraction (%MVC) provides a normalized assessment of muscle exertion that can be compared between individuals. A higher %MVC during tasks can lead to more rapid muscle fatigue and increased risk of injury. This study evaluates the %MVC of forearm muscles while manipulating four laparoscopic energy devices and compares the differences in muscle activity between surgeons with different hand sizes.

Design

Nonexperimental correlational study.

Setting

Testing was performed in a simulation lab at Mayo Clinic Arizona.

Participants

Surgeons and surgical trainees that regularly perform robotic/laparoscopic surgery.

Interventions

Demographic information, glove size, and grip strength were collected. Four advanced energy devices were assessed. Surface electromyography (sEMG) electrodes were applied to the flexor digitorum superficialis (FDS), extensor carpi ulnaris (ECU), extensor carpi radialis longus (ECR), and extensor pollicis longus (EPL) of the dominant hand. Isometric MVC was performed on each muscle. Participants performed opening, closing, and activation cycles for each instrument. EMG output was filtered and normalized to provide %MVC.

Measurements and Main Results

Twenty-four individuals participated. Fourteen were female. Glove sizes ranged from 5.5 to 8.5, with 6.5 being the most common (n = 8). Glove size analysis was split between small (≤ 6.5) and large (>6.5).
When adjusting for training level and instrument used, FDS and ECR displayed statistically significantly higher levels of activation in the small-handed group (p = .0012 and 0.013, respectively). 15% MVC was selected as a cutoff for evaluation due to increased risk of muscle fatigue and injury with sustained use above this threshold. Of the 16 muscle/instrument combinations, 10 showed a mean %MVC of greater than 15% for small hands, with one combination over 15% for large hands.

Conclusion

: Smaller-handed surgeons demonstrate increased forearm muscle activation when using laparoscopic instruments. Industry partners should consider variations in surgeon hand size when developing instruments to prevent disproportionate risk of injury to surgeons with smaller hands.
目的:最大自主收缩百分比(%MVC)提供了一种标准化的肌肉消耗评估,可以在个体之间进行比较。在任务中较高的%MVC会导致更快的肌肉疲劳和增加受伤的风险。本研究评估了在操作四种腹腔镜能量装置时前臂肌肉的%MVC,并比较了不同手大小的外科医生肌肉活动的差异。设计:非实验相关研究。环境:测试在亚利桑那州梅奥诊所的模拟实验室进行。参与者:定期进行机器人/腹腔镜手术的外科医生和外科实习生。干预措施:收集人口统计信息、手套尺寸和握力。评估了四种先进的能源装置。表面肌电(sEMG)电极应用于优势手的指浅屈肌(FDS)、尺腕伸肌(ECU)、桡腕长伸肌(ECR)和拇长伸肌(EPL)。对每块肌肉进行等距MVC。参与者对每个仪器进行打开、关闭和激活循环。肌电图输出经过过滤和规范化以提供%MVC。测量及主要结果:24人参与。14名女性。手套的尺寸从5.5-8.5不等,其中最常见的是6.5 (n=8)。手套尺寸分析分为小(≤6.5)和大(>6.5)。当调整训练水平和使用的仪器时,小手组FDS和ECR的激活水平具有统计学意义上的显著性(p分别= 0.0012和0.013)。由于持续使用超过该阈值会增加肌肉疲劳和损伤的风险,因此选择15% MVC作为评估的截止值。在16个肌肉/器械组合中,10个手部的平均MVC值大于15%,一个手部的组合超过15%。结论:小手外科医生在使用腹腔镜器械时前臂肌肉激活增加。行业合作伙伴在开发器械时应考虑外科医生手的大小变化,以防止手较小的外科医生受到不成比例的伤害。
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引用次数: 0
Onabotulinumtoxin A Injections for Patients With Pelvic Floor Dysfunction A型肉毒杆菌毒素注射治疗盆底功能障碍。
IF 3.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2025-07-24 DOI: 10.1016/j.jmig.2025.07.005
Gabrielle T. Whitmore MD, Jenny Tam MD, Megan S. Orlando MD

Study Objective

To review the current literature surrounding onabotulinum toxin A injections for patients with pelvic floor dysfunction and to show how to perform these injections.

Setting

Academic tertiary care hospital

Design

It is estimated that about 50% to 90% of patients with chronic pelvic pain have pain that originates from myofascial sources, including the pelvic floor muscles. In patients with pelvic floor dysfunction, management consists of pelvic floor physical therapy with the addition of pelvic floor trigger point injections with a local anesthetic as needed. We offer onabotulinum toxin A to individuals who require long-term repeat trigger point injections, have barriers to accessing monthly injections, or show no durable improvement.

Intervention

We show a comprehensive pelvic floor exam and techniques for administering of onabotulinum toxin A to pelvic floor muscles in individuals with pelvic floor dysfunction, as well as a demonstration on a live patient. We perform an exam while the patient is awake, either in the clinic or at the time of the procedure, and examine the pubococcygeus, iliococcygeus, and obturator internus muscles to assess for hypertonicity and tenderness to palpation. Once sedation is initiated, 200 units of onabotulinum toxin A are then reconstituted with 20 mL of normal saline. The pudendal nerve kit allows for 1 cm depth of penetration with the needle. Approximately 1 to 2 mL of onabotulinumtoxin A are injected sequentially in multiple locations along the above-mentioned pelvic floor muscles. Medication effects may last up to 3 to 6 months, with a reduction in pain scores starting at 6 weeks and lasting through 12 weeks based on published literature. Adverse effects may include constipation, urinary incontinence, urinary tract infections, fecal incontinence, or urinary retention.

Conclusions

Onabotulinumtoxin A may be helpful in patients with refractory pelvic floor dysfunction. We show how to perform these injections with a safe and reproducible technique.

Video Abstract

Video: Onabotulinumtoxin A may be helpful in patients with refractory pelvic floor dysfunction, and we demonstrate how to perform these injections safelyDownload: Download video (24MB)
目的:回顾目前有关注射A型肉毒杆菌毒素治疗盆底功能障碍的文献,并说明如何进行注射。参与者:据估计,大约50-90%的慢性盆腔疼痛患者的疼痛来源于肌筋膜,包括盆底肌肉。对于盆底功能障碍患者,治疗包括盆底物理治疗,并根据需要在局部麻醉下进行盆底触发点注射。我们为需要长期重复触发点注射的个体提供肉毒杆菌毒素A,有获得每月注射的障碍,或没有持久改善。干预:我们展示了一个全面的盆底检查和在盆底功能障碍患者的盆底肌肉中施用肉毒杆菌毒素a的技术,以及一个活体患者的演示。我们在病人清醒时进行检查,无论是在诊所还是在手术时,检查耻骨尾骨肌、髂尾骨肌和闭孔内肌,以评估触诊时的高张力和压痛。一旦开始镇静,200单位肉毒杆菌毒素A再与20毫升生理盐水混合。阴部神经套件允许针头插入1cm深度。沿着上述盆底肌肉的多个部位依次注射约1- 2ml肉毒杆菌毒素A。根据已发表的文献,药物效果可能持续3-6个月,疼痛评分从6周开始减少,持续12周。不良反应可能包括便秘、尿失禁、尿路感染、大便失禁或尿潴留。结论:肉毒杆菌毒素A可能对难治性盆底功能障碍患者有帮助。我们演示了如何使用安全和可重复的技术进行这些注射。
{"title":"Onabotulinumtoxin A Injections for Patients With Pelvic Floor Dysfunction","authors":"Gabrielle T. Whitmore MD,&nbsp;Jenny Tam MD,&nbsp;Megan S. Orlando MD","doi":"10.1016/j.jmig.2025.07.005","DOIUrl":"10.1016/j.jmig.2025.07.005","url":null,"abstract":"<div><h3>Study Objective</h3><div>To review the current literature surrounding onabotulinum toxin A injections for patients with pelvic floor dysfunction and to show how to perform these injections.</div></div><div><h3>Setting</h3><div>Academic tertiary care hospital</div></div><div><h3>Design</h3><div>It is estimated that about 50% to 90% of patients with chronic pelvic pain have pain that originates from myofascial sources, including the pelvic floor muscles. In patients with pelvic floor dysfunction, management consists of pelvic floor physical therapy with the addition of pelvic floor trigger point injections with a local anesthetic as needed. We offer onabotulinum toxin A to individuals who require long-term repeat trigger point injections, have barriers to accessing monthly injections, or show no durable improvement.</div></div><div><h3>Intervention</h3><div>We show a comprehensive pelvic floor exam and techniques for administering of onabotulinum toxin A to pelvic floor muscles in individuals with pelvic floor dysfunction, as well as a demonstration on a live patient. We perform an exam while the patient is awake, either in the clinic or at the time of the procedure, and examine the pubococcygeus, iliococcygeus, and obturator internus muscles to assess for hypertonicity and tenderness to palpation. Once sedation is initiated, 200 units of onabotulinum toxin A are then reconstituted with 20 mL of normal saline. The pudendal nerve kit allows for 1 cm depth of penetration with the needle. Approximately 1 to 2 mL of onabotulinumtoxin A are injected sequentially in multiple locations along the above-mentioned pelvic floor muscles. Medication effects may last up to 3 to 6 months, with a reduction in pain scores starting at 6 weeks and lasting through 12 weeks based on published literature. Adverse effects may include constipation, urinary incontinence, urinary tract infections, fecal incontinence, or urinary retention.</div></div><div><h3>Conclusions</h3><div>Onabotulinumtoxin A may be helpful in patients with refractory pelvic floor dysfunction. We show how to perform these injections with a safe and reproducible technique.</div></div><div><h3>Video Abstract</h3><div>Video: Onabotulinumtoxin A may be helpful in patients with refractory pelvic floor dysfunction, and we demonstrate how to perform these injections safely<span><span><span><span><video><source></source></video></span><span><span>Download: <span>Download video (24MB)</span></span></span></span></span></span></div></div>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":"33 3","pages":"Page 257"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144718032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low-grade Appendiceal Mucinous Neoplasm Presenting as Ovarian Cyst 低级别阑尾黏液性肿瘤表现为卵巢囊肿。
IF 3.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2025-05-02 DOI: 10.1016/j.jmig.2025.04.010
Qiaofei Lyu MD, Xiaoyan Chen MD
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引用次数: 0
Endometriosis Among Transgender and Gender Diverse Patients Imaging Study (ETRIS) 跨性别和性别差异患者子宫内膜异位症影像学研究(ETRIS)。
IF 3.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2025-08-28 DOI: 10.1016/j.jmig.2025.08.021
Maddalena Giacomozzi MD, MGH , Donna Ruumpol BSc , Robert de Leeuw MD, PhD , Norah van Mello MD, PhD , Maciej Krasinski MBBS, BSc , Rufus Cartwright MD, PhD, MRCOG , Richard Flint MD, MRCOG , Laura Spinnewijn MD, PhD , Petra Verdonk PhD , Annemiek Nap MD, PhD

Objective

To assess the prevalence of surgically confirmed endometriosis among assigned-female-at-birth (AFAB) transgender and gender diverse (TGD) individuals undergoing laparoscopic pelvic surgery.

Design

Retrospective multicenter cohort study from 2021 to 2024.

Setting

Three academic medical centers in the Netherlands and the United Kingdom.

Participants

Eligible participants were AFAB TGD individuals aged ≥18 years who underwent pelvic laparoscopic surgery for any indication, including gender incongruence/dysphoria.

Interventions

Data on demographics, medical history, and diagnostic imaging were analyzed using descriptive statistics. Surgical confirmation of endometriosis was the primary outcome.

Results

Among 325 participants, endometriosis prevalence was 3.1% (n = 10). The mean age of participants was 27.2 years and the mean body mass index (BMI) 24.9. Testosterone was predominantly used before surgery (95.4%), and among these users, 38.5% had been on testosterone for 5 or more years at the time of surgery. Overall, 6% of the sample reported dysmenorrhea, and among those with endometriosis, 30% experienced dysmenorrhea.

Conclusion

Endometriosis was present in 3.1% of the sample. This finding differs from previous literature as it reports a lower prevalence compared to cisgender women and to other studies on TGD people. This is potentially due to prolonged use of testosterone and early initiation of gender-affirming care (GAC).
目的:评估经手术证实的子宫内膜异位症在接受腹腔镜盆腔手术的变性和性别多样化(TGD)患者中的患病率。设计:2021 - 2024年的回顾性多中心队列研究。环境:荷兰和英国的三个学术医疗中心。参与者:符合条件的参与者是年龄≥18岁的AFAB TGD患者,他们接受了盆腔腹腔镜手术,包括性别不一致/烦躁不安。干预措施:使用描述性统计分析人口统计学、病史和诊断成像数据。手术确认子宫内膜异位症是主要结果。结果:在325名参与者中,子宫内膜异位症患病率为3.1% (n=10)。参与者的平均年龄为27.2岁,平均身体质量指数(BMI)为24.9。手术前主要使用睾酮(95.4%),在这些使用者中,38.5%在手术时已使用睾酮5年或更长时间。总体而言,6%的样本报告痛经,在子宫内膜异位症患者中,30%经历痛经。结论:3.1%的样本存在子宫内膜异位症。这一发现与以前的文献不同,因为它报告的患病率低于顺性女性和其他关于TGD患者的研究。这可能是由于长期使用睾酮和早期开始性别确认护理(GAC)。
{"title":"Endometriosis Among Transgender and Gender Diverse Patients Imaging Study (ETRIS)","authors":"Maddalena Giacomozzi MD, MGH ,&nbsp;Donna Ruumpol BSc ,&nbsp;Robert de Leeuw MD, PhD ,&nbsp;Norah van Mello MD, PhD ,&nbsp;Maciej Krasinski MBBS, BSc ,&nbsp;Rufus Cartwright MD, PhD, MRCOG ,&nbsp;Richard Flint MD, MRCOG ,&nbsp;Laura Spinnewijn MD, PhD ,&nbsp;Petra Verdonk PhD ,&nbsp;Annemiek Nap MD, PhD","doi":"10.1016/j.jmig.2025.08.021","DOIUrl":"10.1016/j.jmig.2025.08.021","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the prevalence of surgically confirmed endometriosis among assigned-female-at-birth (AFAB) transgender and gender diverse (TGD) individuals undergoing laparoscopic pelvic surgery.</div></div><div><h3>Design</h3><div>Retrospective multicenter cohort study from 2021 to 2024.</div></div><div><h3>Setting</h3><div>Three academic medical centers in the Netherlands and the United Kingdom.</div></div><div><h3>Participants</h3><div>Eligible participants were AFAB TGD individuals aged ≥18 years who underwent pelvic laparoscopic surgery for any indication, including gender incongruence/dysphoria.</div></div><div><h3>Interventions</h3><div>Data on demographics, medical history, and diagnostic imaging were analyzed using descriptive statistics. Surgical confirmation of endometriosis was the primary outcome.</div></div><div><h3>Results</h3><div>Among 325 participants, endometriosis prevalence was 3.1% (n = 10). The mean age of participants was 27.2 years and the mean body mass index (BMI) 24.9. Testosterone was predominantly used before surgery (95.4%), and among these users, 38.5% had been on testosterone for 5 or more years at the time of surgery. Overall, 6% of the sample reported dysmenorrhea, and among those with endometriosis, 30% experienced dysmenorrhea.</div></div><div><h3>Conclusion</h3><div>Endometriosis was present in 3.1% of the sample. This finding differs from previous literature as it reports a lower prevalence compared to cisgender women and to other studies on TGD people. This is potentially due to prolonged use of testosterone and early initiation of gender-affirming care (GAC).</div></div>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":"33 3","pages":"Pages 308-315"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk Factors for Reoperation and Subsequent Uterine Preservation in Congenital Cervical Malformation 先天性宫颈畸形再手术及后续子宫保留的危险因素。
IF 3.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2025-11-26 DOI: 10.1016/j.jmig.2025.11.011
Shuwen Zhang MD , Na Chen MD , Si Su MD , Jia Kang MD , Shuang Song MD , Lan Zhu MD

Objective

To primarily evaluate the occurrence, causes, and risk factors of reoperation in patients with congenital cervical malformation, and secondarily to investigate the determinants of subsequent uterine preservation in this population.

Design

Retrospective case-control study.

Setting

A tertiary referring hospital in China.

Participants

A total of 82 patients with congenital cervical malformation between January 2003 and April 2024.

Interventions

Retrospective chart review and follow-up of patients diagnosed with congenital cervical malformation, including collection of data on demographics, disease characteristics, surgical details, reoperation timing and causes, and uterine preservation outcomes.

Results

Among 82 patients, 47 (57.3%) underwent only one surgery without requiring reoperation, while 35 (42.7%) underwent reoperation. The median age at initial surgery was 13 (interquartile range, 12–16) years. The interval between primary and secondary surgeries ranged from 2 weeks to 12 years (mean 32.6 months). The main causes for reoperation included infection with fever, pelvic mass formation, restenosis or obstruction, and persistent abdominal pain. An accurate initial diagnosis and the placement of a cervical stent during the initial procedure were associated with prolonged reoperation-free survival (p < .05). Among the 35 patients who underwent reoperation, 19 (54.29%) successfully preserved the uterus, while 16 (45.71%) ultimately required hysterectomy. Cervical obstruction type was independently associated with successful uterine preservation (p = .005).

Conclusion

An accurate initial diagnosis and intraoperative placement of a cervical stent were associated with longer reoperation-free intervals. Notably, patients with cervical obstruction demonstrated higher success rates with uterine-sparing procedures compared to those with other types of congenital cervical malformation.
目的:评价先天性宫颈畸形患者再次手术的发生、原因及危险因素,探讨该人群后续子宫保留的决定因素。设计:回顾性病例对照研究。单位:国内三级转诊医院。研究对象:2003年1月至2024年4月共82例先天性颈椎畸形患者。干预措施:对诊断为先天性宫颈畸形的患者进行回顾性图表回顾和随访,包括人口统计学、疾病特征、手术细节、再手术时机和原因、子宫保存结果等数据的收集。结果:82例患者中,47例(57.3%)仅行一次手术,无需再手术,35例(42.7%)再次手术。初次手术的中位年龄为13岁(IQR, 12-16岁)。初次和二次手术之间的间隔为2周至12年(平均32.6个月)。再次手术的主要原因为发热感染、盆腔肿块形成、再狭窄或梗阻、持续腹痛。准确的初始诊断和在初始手术期间放置颈部支架与延长无再手术生存期相关(P < 0.05)。35例再次手术患者中,成功保留子宫19例(54.29%),最终切除子宫16例(45.71%)。宫颈阻塞类型与子宫保存成功与否独立相关(P = 0.005)。结论:准确的初步诊断和术中置入颈椎支架与较长的无再手术间隔相关。值得注意的是,与其他类型的先天性宫颈畸形相比,宫颈阻塞患者在保留子宫手术中表现出更高的成功率。
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引用次数: 0
Postoperative Hysterectomy Complications: Comparing Novel Versus Traditional Hemoglobin A1c Cut-Offs 子宫切除术后并发症:比较新型与传统的血红蛋白A1c切断。
IF 3.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2025-11-28 DOI: 10.1016/j.jmig.2025.11.016
Noelle Matese MD , Xi Wang BS , Suman Sahil MBA , An-Lin Cheng PhD , Carsen Steele BS , Alleana Corpin BA , Jonathan P. Shepherd MD , Gary Sutkin MD

Study Objective

To investigate the correlation between HbA1c and complications after hysterectomies.

Design

Retrospective cohort analysis.

Setting

Cerner Health Facts (519 million patient encounters from 750 hospitals).

Patients

Patients undergoing laparoscopic ± robotic-assisted, vaginal, or abdominal hysterectomy, January 2010 to November 2018. We included patients with perioperative HbA1c values, including those diagnosed with diabetes or undergoing screening.

Interventions

We performed univariable and multivariable logistic regressions with the outcome a composite of any post-op complication. We adjusted for HbA1c as continuous and categorical variables using HbA1c (>8.0% based on guidelines and >8.85% based on receiver operating characteristic analysis from current dataset) as cut-points.

Measurements and Main Results

Of 86,420 hysterectomies, 2693 (3.1%) had nonexcluded HbA1c, including 514 (19.1%) with complications and 2179 (80.9%) without. Median time to complication was 18 days. Patients were 75.2% white, 83.2% in urban hospitals. Route was predominantly minimally invasive: 30.5% laparoscopic, 25.6% vaginal, 43.9% abdominal, with 69.8% adnexa removed. Patients with complications were older (60.5 ± 15.9 vs 58.4 ± 14.2 years, p = .004), more likely from the Southern US (24.5% vs 18.5%, p = .006), used tobacco (26.7% vs 19.0%, p < .001), and were obese (32.3% vs 23.3%, p < .001). Most complications were infectious (87.4%). Higher HbA1c was associated with more complications, whether continuous (p = .03), HbA1c > 8.0% (p = .01), or HbA1c > 8.85% (p = .001). HbA1c > 8.85% optimized test characteristics (sensitivity = 0.14, specificity = 0.91, PPV = 0.27, NPV = 0.82). Predictive value improved with confounders (area under the curve = 0.71–0.72), and multivariable analysis demonstrated HbA1c > 8.85% increased complications (odds ratio [OR] = 1.71, 95% CI = 1.25–2.32). Obesity (OR = 1.31, 95% CI = 1.04–1.64) and urogynecological diagnoses, including urinary frequency, history of urinary tract infection, and dysuria (OR = 2.31, 3.71, 3.98, respectively), also increased complications.

Conclusion

HbA1c as a continuous variable impacted complications, so HbA1c reductions will likely decrease complications. For surgeons deciding to proceed with hysterectomy based on preoperative HbA1c, 8.0% and 8.85% are both acceptable cut-points. Multivariable models outperformed HbA1c alone, warranting further research to predict complications.
研究目的:探讨HbA1c与子宫切除术后并发症的关系。设计:回顾性队列分析。环境:Cerner Health Facts(来自750家医院的5.19亿患者就诊情况)。患者:2010年1月至2018年11月接受腹腔镜±机器人辅助、阴道或腹部子宫切除术的患者。我们纳入了围手术期HbA1c值的患者,包括诊断为糖尿病或正在接受筛查的患者。干预措施:我们进行了单变量和多变量logistic回归,结果是任何术后并发症的复合。我们使用HbA1c(基于指南的>为8.0%,基于当前数据集的ROC分析>为8.85%)作为切点调整HbA1c作为连续和分类变量。测量结果和主要结果:在86420例子宫切除术中,2693例(3.1%)有非排除性HbA1c,其中514例(19.1%)有并发症,2179例(80.9%)无并发症。发生并发症的中位时间为18天。白人占75.2%,城市医院占83.2%。途径主要是微创:30.5%腹腔镜,25.6%阴道,43.9%腹部,69.8%附件切除。并发症患者年龄较大(60.5±15.9岁vs 58.4±14.2岁,p= 0.004),更可能来自美国南部(24.5% vs 18.5%, p= 0.006),吸烟(26.7% vs 19.0%), p1c与更多并发症相关,无论是否持续(p= 0.03), HbA1c >8.0% (p= 0.01),或HbA1c >8.85% (p= 0.001)。HbA1c >8.85%优化检测特征(灵敏度= 0.14,特异性= 0.91,PPV= 0.27, NPV= 0.82)。混杂因素提高了预测价值(AUC= 0.71 - 0.72),多变量分析显示HbA1c >使并发症增加8.85% (OR=1.71, 95% CI=1.25-2.32)。肥胖(OR=1.31, 95% CI=1.04-1.64)和泌尿妇科诊断包括尿频、尿路感染史和排尿困难(OR分别为2.31、3.71、3.98)也增加了并发症。结论:HbA1c作为一个持续变量影响并发症,因此降低HbA1c可能会减少并发症。对于术前HbA1c决定进行子宫切除术的外科医生来说,8.0%和8.85%都是可接受的切点。多变量模型优于单独的HbA1c,值得进一步研究以预测并发症。
{"title":"Postoperative Hysterectomy Complications: Comparing Novel Versus Traditional Hemoglobin A1c Cut-Offs","authors":"Noelle Matese MD ,&nbsp;Xi Wang BS ,&nbsp;Suman Sahil MBA ,&nbsp;An-Lin Cheng PhD ,&nbsp;Carsen Steele BS ,&nbsp;Alleana Corpin BA ,&nbsp;Jonathan P. Shepherd MD ,&nbsp;Gary Sutkin MD","doi":"10.1016/j.jmig.2025.11.016","DOIUrl":"10.1016/j.jmig.2025.11.016","url":null,"abstract":"<div><h3>Study Objective</h3><div>To investigate the correlation between HbA<sub>1c</sub> and complications after hysterectomies.</div></div><div><h3>Design</h3><div>Retrospective cohort analysis.</div></div><div><h3>Setting</h3><div>Cerner Health Facts (519 million patient encounters from 750 hospitals).</div></div><div><h3>Patients</h3><div>Patients undergoing laparoscopic ± robotic-assisted, vaginal, or abdominal hysterectomy, January 2010 to November 2018. We included patients with perioperative HbA<sub>1c</sub> values, including those diagnosed with diabetes or undergoing screening.</div></div><div><h3>Interventions</h3><div>We performed univariable and multivariable logistic regressions with the outcome a composite of any post-op complication. We adjusted for HbA<sub>1c</sub> as continuous and categorical variables using HbA<sub>1c</sub> (&gt;8.0% based on guidelines and &gt;8.85% based on receiver operating characteristic analysis from current dataset) as cut-points.</div></div><div><h3>Measurements and Main Results</h3><div>Of 86,420 hysterectomies, 2693 (3.1%) had nonexcluded HbA<sub>1c</sub>, including 514 (19.1%) with complications and 2179 (80.9%) without. Median time to complication was 18 days. Patients were 75.2% white, 83.2% in urban hospitals. Route was predominantly minimally invasive: 30.5% laparoscopic, 25.6% vaginal, 43.9% abdominal, with 69.8% adnexa removed. Patients with complications were older (60.5 ± 15.9 vs 58.4 ± 14.2 years, p = .004), more likely from the Southern US (24.5% vs 18.5%, p = .006), used tobacco (26.7% vs 19.0%, p &lt; .001), and were obese (32.3% vs 23.3%, p &lt; .001). Most complications were infectious (87.4%). Higher HbA<sub>1c</sub> was associated with more complications, whether continuous (p = .03), HbA<sub>1c</sub> &gt; 8.0% (p = .01), or HbA<sub>1c</sub> &gt; 8.85% (p = .001). HbA<sub>1c</sub> &gt; 8.85% optimized test characteristics (sensitivity = 0.14, specificity = 0.91, PPV = 0.27, NPV = 0.82). Predictive value improved with confounders (area under the curve = 0.71–0.72), and multivariable analysis demonstrated HbA<sub>1c</sub> &gt; 8.85% increased complications (odds ratio [OR] = 1.71, 95% CI = 1.25–2.32). Obesity (OR = 1.31, 95% CI = 1.04–1.64) and urogynecological diagnoses, including urinary frequency, history of urinary tract infection, and dysuria (OR = 2.31, 3.71, 3.98, respectively), also increased complications.</div></div><div><h3>Conclusion</h3><div>HbA<sub>1c</sub> as a continuous variable impacted complications, so HbA<sub>1c</sub> reductions will likely decrease complications. For surgeons deciding to proceed with hysterectomy based on preoperative HbA<sub>1c</sub>, 8.0% and 8.85% are both acceptable cut-points. Multivariable models outperformed HbA<sub>1c</sub> alone, warranting further research to predict complications.</div></div>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":"33 3","pages":"Pages 275-282"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145648846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Current State of AAGL–Fellowship in Minimally Invasive Gynecologic Surgery: Surgical Volume and Case Types AAGL妇科微创外科奖学金(FMIGS)的现状:手术量和病例类型。
IF 3.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2025-12-06 DOI: 10.1016/j.jmig.2025.12.002
Katie Kwon MD , Francesca Lim MS , Courtney Lim MD , Stephanie Morris MD , Hye-Chun Hur MD, MPH

Study Objective

To describe the current state of the American Association of Gynecologic Laparoscopists (AAGL)–Fellowship in Minimally Invasive Gynecologic Surgery (FMIGS) programs, assessing case volume, case types, and differences among programs.

Design

Retrospective cohort study.

Setting

FMIGS in the United States.

Patients

All fellows who started and completed an AAGL-FMIGS program in the United States between 2020 and 2024.

Interventions

Not applicable.

Measurements and Main Results

During the study period, 130 fellows completed a 2 or 3-year fellowship from start to finish among 52 fellowships. The median number of total cases completed in a 2-year fellowship was 510 (interquartile range [IQR], 428–586). The most common procedure was hysterectomy (median, 210 [IQR, 174–255]), followed by peritoneal procedures, which included retroperitoneal dissection and adhesiolysis (median, 125 [IQR 91–167]), and endometriosis procedures (median, 89 [IQR, 56–132]). The medians for other case types were as follows: myomectomies (including hysteroscopic), 62 (IQR, 40–95); adnexal surgeries, 39 (IQR, 25–67); and hysteroscopies (excluding hysteroscopic myomectomy), 45 (IQR, 35–77). Among the 130 fellows, 67% (n = 87) had FMIGS-trained program directors and 33% (n = 43) had non-FMIGS-trained program directors. Fellows from programs with FMIGS-trained program directors had greater surgical volume than fellows with non-FMIGS-trained program directors (median number of cases per fellow, 537 [IQR, 468–620] vs 464 [IQR, 367–551]; p = .03). Furthermore, fellows from programs with FMIGS-trained program directors compared with those with non-FMIGS-trained program directors completed a median of 108 vs 58 endometriosis surgeries (p = .01), 71 vs 44 myomectomies (p = .01), 52 vs 39 hysteroscopies (p = .06), and 215 vs 187 hysterectomies (p = .27), respectively.

Conclusion

Adopting the Accreditation Council for Graduate Medical Education case log system provided greater insight into the volume and types of cases completed in AAGL-FMIGS programs. Overall, AAGL-FMIGS programs have robust surgical volume with program director training affecting volume and case types. Fellows from programs with FMIGS-trained program directors have significantly greater total case volume, myomectomies, and endometriosis surgeries.
目的:描述AAGL-FMIGS奖学金项目的现状,评估病例数量、病例类型和项目之间的差异。设计:回顾性队列研究。背景:美国微创妇科外科奖学金(FMIGS)。参与者:所有在2020年至2024年期间在美国开始并完成AAGL-FMIGS奖学金的研究员。结果:在研究期间,在52项研究中,130名研究人员从头到尾完成了2 - 3年的研究。在为期2年的研究中完成的总病例数中位数为510例[IQR 428-586]。最常见的手术是子宫切除术(中位数210 [IQR 174-255]),其次是腹膜手术,包括腹膜后剥离和粘连松解(中位数125 [IQR 91-167])和子宫内膜异位症手术(中位数89 [IQR 56-132])。其他病例类型的中位数为:子宫肌瘤切除术(包括宫腔镜)62例[IQR 40-95],附件手术39例[IQR 25-67],宫腔镜(不包括宫腔镜子宫肌瘤切除术)45例[IQR 35-77]。在130名研究员中,67% (n= 87)是fmigs培训的项目主任,33% (n= 43)是非fmigs培训的项目主任。与未接受fmigs培训的项目主任相比,接受过fmigs培训的项目主任的项目成员的手术量更大(每位成员的中位数为537例[IQR 468-620] vs 464例[IQR 367-551], p=.03)。此外,与未受过fmigs培训的项目主任相比,受过fmigs培训的项目主任的项目成员完成子宫内膜异位症手术的中位数为108例,而58例(p= 0.01),子宫肌瘤切除术的中位数为71例,子宫肌瘤切除术的中位数为44例(p = )。01), 52对39 (p=.06), 215对187 (p=.27)子宫切除术。结论:采用ACGME病例日志系统可以更深入地了解AAGL-FMIGS项目中完成的病例数量和类型。总体而言,AAGL-FMIGS项目具有强大的手术量,项目主任培训影响了手术量和病例类型。经过fmigs培训的项目主任的项目成员的总病例量、子宫肌瘤切除术和子宫内膜异位症手术显著增加。
{"title":"The Current State of AAGL–Fellowship in Minimally Invasive Gynecologic Surgery: Surgical Volume and Case Types","authors":"Katie Kwon MD ,&nbsp;Francesca Lim MS ,&nbsp;Courtney Lim MD ,&nbsp;Stephanie Morris MD ,&nbsp;Hye-Chun Hur MD, MPH","doi":"10.1016/j.jmig.2025.12.002","DOIUrl":"10.1016/j.jmig.2025.12.002","url":null,"abstract":"<div><h3>Study Objective</h3><div>To describe the current state of the American Association of Gynecologic Laparoscopists (AAGL)–Fellowship in Minimally Invasive Gynecologic Surgery (FMIGS) programs, assessing case volume, case types, and differences among programs.</div></div><div><h3>Design</h3><div>Retrospective cohort study.</div></div><div><h3>Setting</h3><div>FMIGS in the United States.</div></div><div><h3>Patients</h3><div>All fellows who started and completed an AAGL-FMIGS program in the United States between 2020 and 2024.</div></div><div><h3>Interventions</h3><div>Not applicable.</div></div><div><h3>Measurements and Main Results</h3><div>During the study period, 130 fellows completed a 2 or 3-year fellowship from start to finish among 52 fellowships. The median number of total cases completed in a 2-year fellowship was 510 (interquartile range [IQR], 428–586). The most common procedure was hysterectomy (median, 210 [IQR, 174–255]), followed by peritoneal procedures, which included retroperitoneal dissection and adhesiolysis (median, 125 [IQR 91–167]), and endometriosis procedures (median, 89 [IQR, 56–132]). The medians for other case types were as follows: myomectomies (including hysteroscopic), 62 (IQR, 40–95); adnexal surgeries, 39 (IQR, 25–67); and hysteroscopies (excluding hysteroscopic myomectomy), 45 (IQR, 35–77). Among the 130 fellows, 67% (n = 87) had FMIGS-trained program directors and 33% (n = 43) had non-FMIGS-trained program directors. Fellows from programs with FMIGS-trained program directors had greater surgical volume than fellows with non-FMIGS-trained program directors (median number of cases per fellow, 537 [IQR, 468–620] vs 464 [IQR, 367–551]; p = .03). Furthermore, fellows from programs with FMIGS-trained program directors compared with those with non-FMIGS-trained program directors completed a median of 108 vs 58 endometriosis surgeries (p = .01), 71 vs 44 myomectomies (p = .01), 52 vs 39 hysteroscopies (p = .06), and 215 vs 187 hysterectomies (p = .27), respectively.</div></div><div><h3>Conclusion</h3><div>Adopting the Accreditation Council for Graduate Medical Education case log system provided greater insight into the volume and types of cases completed in AAGL-FMIGS programs. Overall, AAGL-FMIGS programs have robust surgical volume with program director training affecting volume and case types. Fellows from programs with FMIGS-trained program directors have significantly greater total case volume, myomectomies, and endometriosis surgeries.</div></div>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":"33 3","pages":"Pages 297-307"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145708467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safe Without Suction: Double-Blind Randomized Controlled Trial Challenges Routine Gastric Decompression in Laparoscopy 安全无抽吸:双盲随机对照试验挑战常规腹腔镜胃减压。
IF 3.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2026-03-01 Epub Date: 2025-12-13 DOI: 10.1016/j.jmig.2025.12.016
Kristina Karlson MD, Capt, USAF, MC , Annie Gauf MD , Petra Voigt MD , Lulu Yu MD , Linda Yang MD , Angela Chaudhari MD , Susan Tsai MD , Jungwha Lee PhD, MPH , Magdy P. Milad MD, MS

Objective

This study aimed to evaluate the necessity of intraoperative gastric decompression during gynecologic laparoscopy.

Methods

This study is a double-blind randomized controlled trial in which participants undergoing any benign gynecologic laparoscopy procedure with umbilical entry were block randomized (1:1) to either receive gastric decompression or not. Individuals were screened for eligibility based on surgical scheduling for gynecologic laparoscopy undergoing umbilical entry. The intervention was performed after the patient was intubated and while the surgeon was out of the operating room to maintain blinding. At the time of laparoscopic entry, surgeons subjectively assessed the degree of stomach decompression, risk of gastric injury, and distance between the umbilicus and inferior gastric margin. A sample size calculation determined that 73 participants per group were needed.

Results

From November 2023 to March 2025, 155 participants were consented to participate and 146 were enrolled and randomized. Participants in the study and control groups did not significantly vary based on age (37.8 vs 36.8), body mass index (27.3 vs 27.9), or procedure type. The primary outcome, stomach well decompressed, was achieved in 97.2% of participants in the study group without an orogastric (OG) tube and 98.5% in the control group with an OG tube (difference, −1.3%; 95% confidence interval, −8.8 to 6.2; p = .01 for noninferiority), with noninferiority margin set at −10%. There were no cases of gastric injury in both groups.

Conclusion

Routine gastric decompression during gynecologic laparoscopy with umbilical entry is not necessary for low-risk participants. Regardless of the placement of an OG tube, the stomach was adequately decompressed, not at risk of injury, and without negative postoperative participant experience.
目的:探讨妇科腹腔镜术中胃减压的必要性。方法:本研究是一项双盲随机对照试验,在该试验中,接受任何良性妇科腹腔镜手术的参与者被随机分组(1:1)接受胃减压或不接受胃减压。个体筛选的资格基于手术计划的妇科腹腔镜手术进行脐部进入。干预是在患者插管后进行的,而外科医生则不在手术室以保持盲法。腹腔镜入路时,术者主观评估胃减压程度、胃损伤风险、脐距胃下缘距离。样本量计算确定为每组73名参与者。结果:从2023年11月至2025年3月,155名受试者同意参与,146名受试者入组并随机分组。研究组和对照组的参与者在年龄(37.8 vs 36.8)、BMI (27.3 vs 27.9)或手术类型上没有显著差异。无胃管研究组97.2%的受试者实现了胃减压,对照组98.5%的受试者实现了胃减压(差异为-1.3%,95%可信区间[CI], -8.8%至6.2%;非劣效性P=0.01),非劣效性裕度为-10%。两组均无胃损伤病例。结论:低危患者无需在脐入路妇科腹腔镜下进行常规胃减压。无论是否放置OG管,胃都得到了充分的减压,没有损伤的风险,也没有不良的术后参与者体验。
{"title":"Safe Without Suction: Double-Blind Randomized Controlled Trial Challenges Routine Gastric Decompression in Laparoscopy","authors":"Kristina Karlson MD, Capt, USAF, MC ,&nbsp;Annie Gauf MD ,&nbsp;Petra Voigt MD ,&nbsp;Lulu Yu MD ,&nbsp;Linda Yang MD ,&nbsp;Angela Chaudhari MD ,&nbsp;Susan Tsai MD ,&nbsp;Jungwha Lee PhD, MPH ,&nbsp;Magdy P. Milad MD, MS","doi":"10.1016/j.jmig.2025.12.016","DOIUrl":"10.1016/j.jmig.2025.12.016","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to evaluate the necessity of intraoperative gastric decompression during gynecologic laparoscopy.</div></div><div><h3>Methods</h3><div>This study is a double-blind randomized controlled trial in which participants undergoing any benign gynecologic laparoscopy procedure with umbilical entry were block randomized (1:1) to either receive gastric decompression or not. Individuals were screened for eligibility based on surgical scheduling for gynecologic laparoscopy undergoing umbilical entry. The intervention was performed after the patient was intubated and while the surgeon was out of the operating room to maintain blinding. At the time of laparoscopic entry, surgeons subjectively assessed the degree of stomach decompression, risk of gastric injury, and distance between the umbilicus and inferior gastric margin. A sample size calculation determined that 73 participants per group were needed.</div></div><div><h3>Results</h3><div>From November 2023 to March 2025, 155 participants were consented to participate and 146 were enrolled and randomized. Participants in the study and control groups did not significantly vary based on age (37.8 vs 36.8), body mass index (27.3 vs 27.9), or procedure type. The primary outcome, stomach well decompressed, was achieved in 97.2% of participants in the study group without an orogastric (OG) tube and 98.5% in the control group with an OG tube (difference, −1.3%; 95% confidence interval, −8.8 to 6.2; p = .01 for noninferiority), with noninferiority margin set at −10%. There were no cases of gastric injury in both groups.</div></div><div><h3>Conclusion</h3><div>Routine gastric decompression during gynecologic laparoscopy with umbilical entry is not necessary for low-risk participants. Regardless of the placement of an OG tube, the stomach was adequately decompressed, not at risk of injury, and without negative postoperative participant experience.</div></div>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":"33 3","pages":"Pages 332-338"},"PeriodicalIF":3.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145762979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of minimally invasive gynecology
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