Pub Date : 2025-02-01DOI: 10.1016/j.jmig.2024.10.001
Ok-Ju Kang MD, Joo-Hyun Nam MD, PhD, Jeong-Yeol Park MD, PhD
Study Objective
To evaluate the efficacy of hemostatic sealant versus electrosurgical energy in achieving hemostasis and preserving postoperative ovarian reserve during laparoscopic ovarian cystectomy.
Design
Randomized controlled trial.
Setting
Single-center study.
Patients
A total of 121 patients undergoing laparoscopic ovarian cystectomy.
Interventions
Patients were randomized to receive either hemostatic sealant or electrosurgical energy for hemostasis during surgery.
Measurements and Main Results
The primary outcome measured was the time required to achieve hemostasis. Secondary outcomes included operating time, estimated blood loss, and assessment of postoperative ovarian reserve through hormone levels (anti-Müllerian hormone [AMH], follicle-stimulating hormone [FSH], E2, inhibin) at three follow-up intervals. The results showed comparable hemostasis times between the two groups. Postoperative hormone levels indicated no significant differences in the impact on ovarian reserve between the groups, except in cases of bilateral ovarian cystectomy, where the hemostatic sealant group exhibited a lesser decline in AMH levels.
Conclusion
Both hemostatic sealant and electrosurgical energy showed equivalent effectiveness in achieving hemostasis during laparoscopic ovarian cystectomy, with comparable results in hemostasis time, blood loss, postoperative complications, and ovarian reserve preservation. However, in cases of bilateral ovarian cystectomy, the hemostatic sealant group exhibited a lesser decline in AMH levels, suggesting a potential advantage in preserving ovarian reserve in these specific cases.
{"title":"Comparative Analysis of Electrosurgical Energy and Hemostatic Sealant for Hemostasis in Laparoscopic Ovarian Cystectomy: A Randomized Controlled Phase III Study","authors":"Ok-Ju Kang MD, Joo-Hyun Nam MD, PhD, Jeong-Yeol Park MD, PhD","doi":"10.1016/j.jmig.2024.10.001","DOIUrl":"10.1016/j.jmig.2024.10.001","url":null,"abstract":"<div><h3>Study Objective</h3><div>To evaluate the efficacy of hemostatic sealant versus electrosurgical energy in achieving hemostasis and preserving postoperative ovarian reserve during laparoscopic ovarian cystectomy.</div></div><div><h3>Design</h3><div>Randomized controlled trial.</div></div><div><h3>Setting</h3><div>Single-center study.</div></div><div><h3>Patients</h3><div>A total of 121 patients undergoing laparoscopic ovarian cystectomy.</div></div><div><h3>Interventions</h3><div>Patients were randomized to receive either hemostatic sealant or electrosurgical energy for hemostasis during surgery.</div></div><div><h3>Measurements and Main Results</h3><div>The primary outcome measured was the time required to achieve hemostasis. Secondary outcomes included operating time, estimated blood loss, and assessment of postoperative ovarian reserve through hormone levels (anti-Müllerian hormone [AMH], follicle-stimulating hormone [FSH], E2, inhibin) at three follow-up intervals. The results showed comparable hemostasis times between the two groups. Postoperative hormone levels indicated no significant differences in the impact on ovarian reserve between the groups, except in cases of bilateral ovarian cystectomy, where the hemostatic sealant group exhibited a lesser decline in AMH levels.</div></div><div><h3>Conclusion</h3><div>Both hemostatic sealant and electrosurgical energy showed equivalent effectiveness in achieving hemostasis during laparoscopic ovarian cystectomy, with comparable results in hemostasis time, blood loss, postoperative complications, and ovarian reserve preservation. However, in cases of bilateral ovarian cystectomy, the hemostatic sealant group exhibited a lesser decline in AMH levels, suggesting a potential advantage in preserving ovarian reserve in these specific cases.</div></div>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":"32 2","pages":"Pages 177-184"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.jmig.2024.08.008
Adi Dayan-Schwartz MD, MHA , Saleh Agbaria MD , Suzan Abd Elgani MD , Liron Kogan MD
{"title":"A Challenging Case of IUD Retrieval From the Colon","authors":"Adi Dayan-Schwartz MD, MHA , Saleh Agbaria MD , Suzan Abd Elgani MD , Liron Kogan MD","doi":"10.1016/j.jmig.2024.08.008","DOIUrl":"10.1016/j.jmig.2024.08.008","url":null,"abstract":"","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":"32 2","pages":"Pages 94-97"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.jmig.2024.08.024
Leilei Hu MD, Dan Liao MD
{"title":"Regarding “The Effect of Hormonal Treatment on Ovarian Endometriomas: A Systematic Review and Meta-Analysis”","authors":"Leilei Hu MD, Dan Liao MD","doi":"10.1016/j.jmig.2024.08.024","DOIUrl":"10.1016/j.jmig.2024.08.024","url":null,"abstract":"","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":"32 2","pages":"Page 198"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.jmig.2025.01.001
Gary N. Frishman MD , Jason A. Abbott PhD, FRANZCOG, FRCOG B Med (Hons)
{"title":"Introducing our Deputy Editor of Health Equity","authors":"Gary N. Frishman MD , Jason A. Abbott PhD, FRANZCOG, FRCOG B Med (Hons)","doi":"10.1016/j.jmig.2025.01.001","DOIUrl":"10.1016/j.jmig.2025.01.001","url":null,"abstract":"","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":"32 2","pages":"Page 93"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143347648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.jmig.2024.09.015
Marla E. Scott MD, Dani Ashak MD, Wilkin F. Muñoz Orozco BS, Allison E. Axtell MD, Scott E. Lentz MD
Study Objective
To evaluate whether extraction laparotomy (EL) for intact specimen removal adversely affected the feasibility or safety of same-day discharge (SDD) in patients undergoing minimally invasive surgery (MIS) for confirmed or suspected gynecologic malignancies.
Design
Retrospective study.
Setting
Single-institution study.
Patients
Patients undergoing MIS for gynecologic malignancy at a single institution, who underwent EL (N = 67) and age-matched controls (N = 134).
Interventions
Comparing SDD rates, complications, readmission, and outpatient follow-up after between patients requiring EL and those who did not after minimally invasive gynecologic surgery.
Measurements and Main Results
A total of 1224 patients were identified. Sixty-seven patients underwent EL for specimen extraction. From the remainder, 134 patients were selected as age-matched controls. SDD rate was 83% (EL) vs 87% (no EL) (p = .39). There was no difference in median pain scores (1.8 vs 1.9 p = .86), length of stay (0 days for both) (p = .41), 30-day readmission rate (6% vs 3%) (p = .45), emergency department visit (13% vs 10%) (p = .76), or any patient contact (34% vs 39%) (p = .53), between the groups. Specimen weight was higher for EL (524 g vs 142 g, p <.001), as was estimated blood loss (104 mL vs 46 mL, p <.001), and surgery time was increased by 22 minutes in the EL group (121 min vs 99 min, p <.001). Patients who underwent EL did require more narcotics in postanesthesia care unit (20.5 vs 12.2 oral morphine equivalent, p = .033); however, this did not translate to increased number of narcotics prescribed at discharge. On logistic regression, a higher specimen weight trended to increase the likelihood of admission (odds ratio, 1.04; confidence interval, 1.01–1.08); however, surgery time, time in postanesthesia care unit, race, body mass index, surgery type, or need for EL did not predict SDD or need for admission.
Conclusion
MIS patients who require EL can still achieve SDD. SDD is safe and feasible without increased risk of readmission, pain score, or unscheduled patient contact postoperatively.
研究目的评估因确诊或疑似妇科恶性肿瘤而接受微创手术(MIS)的患者,因完整标本取出而进行的开腹手术(EL)是否会对当日出院(SDD)的可行性或安全性产生不利影响:回顾性研究患者: 接受微创手术的患者在单个机构接受微创手术治疗妇科恶性肿瘤的患者(67人)和年龄匹配的对照组(134人):比较微创妇科手术后需要拔管开腹的患者与不需要拔管开腹的患者的当日出院率、并发症、再入院率和门诊随访率:共确定了 1224 名患者。67名患者接受了EL标本提取术。其余 134 名患者被选为年龄匹配的对照组。SDD率为83%(EL)对87%(无EL)(P=0.39)。两组患者的疼痛评分中位数(1.8 vs. 1.9,p=.86)、住院时间(LOS)(两组均为 0 天)(p=.41)、30 天再入院率(6% vs. 3%,p=.45)、急诊室就诊率(13% vs. 10%,p=.76)或任何患者接触率(34% vs. 39%,p=.53)均无差异。EL组的标本重量更高(524克对142克,p结论:需要开腹取材的微创手术患者仍可实现 SDD。当天出院是安全可行的,不会增加术后再入院风险、疼痛评分或计划外的患者接触。
{"title":"Extraction Laparotomy for Specimen Retrieval Does Not Alter Same-Day Discharge Plans","authors":"Marla E. Scott MD, Dani Ashak MD, Wilkin F. Muñoz Orozco BS, Allison E. Axtell MD, Scott E. Lentz MD","doi":"10.1016/j.jmig.2024.09.015","DOIUrl":"10.1016/j.jmig.2024.09.015","url":null,"abstract":"<div><h3>Study Objective</h3><div>To evaluate whether extraction laparotomy (EL) for intact specimen removal adversely affected the feasibility or safety of same-day discharge (SDD) in patients undergoing minimally invasive surgery (MIS) for confirmed or suspected gynecologic malignancies.</div></div><div><h3>Design</h3><div>Retrospective study.</div></div><div><h3>Setting</h3><div>Single-institution study.</div></div><div><h3>Patients</h3><div>Patients undergoing MIS for gynecologic malignancy at a single institution, who underwent EL (N = 67) and age-matched controls (N = 134).</div></div><div><h3>Interventions</h3><div>Comparing SDD rates, complications, readmission, and outpatient follow-up after between patients requiring EL and those who did not after minimally invasive gynecologic surgery.</div></div><div><h3>Measurements and Main Results</h3><div>A total of 1224 patients were identified. Sixty-seven patients underwent EL for specimen extraction. From the remainder, 134 patients were selected as age-matched controls. SDD rate was 83% (EL) vs 87% (no EL) (p = .39). There was no difference in median pain scores (1.8 vs 1.9 p = .86), length of stay (0 days for both) (p = .41), 30-day readmission rate (6% vs 3%) (p = .45), emergency department visit (13% vs 10%) (p = .76), or any patient contact (34% vs 39%) (p = .53), between the groups. Specimen weight was higher for EL (524 g vs 142 g, p <.001), as was estimated blood loss (104 mL vs 46 mL, p <.001), and surgery time was increased by 22 minutes in the EL group (121 min vs 99 min, p <.001). Patients who underwent EL did require more narcotics in postanesthesia care unit (20.5 vs 12.2 oral morphine equivalent, p = .033); however, this did not translate to increased number of narcotics prescribed at discharge. On logistic regression, a higher specimen weight trended to increase the likelihood of admission (odds ratio, 1.04; confidence interval, 1.01–1.08); however, surgery time, time in postanesthesia care unit, race, body mass index, surgery type, or need for EL did not predict SDD or need for admission.</div></div><div><h3>Conclusion</h3><div>MIS patients who require EL can still achieve SDD. SDD is safe and feasible without increased risk of readmission, pain score, or unscheduled patient contact postoperatively.</div></div>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":"32 2","pages":"Pages 159-165"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142289334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.jmig.2024.10.013
Gaofa Wang PhD, Yuanjun Zhu MD, Na Duan BSN, Chong Guo PhD, Nannan Liu BSN, Hanling Huang MD
Objective
To determine the role of Platelet-rich plasma (PRP) in improving pregnancy and adhesion recurrence outcomes in women who underwent hysteroscopic treatment of intrauterine adhesions.
Data Sources
A total of 3 databases: Google scholar, PubMed, and clinicaltrials.gov were searched extensively from inception until April 5, 2023, without any language restrictions.
Methods of Study selection
After the removal of duplicates, studies were first scrutinized on the basis of title/abstract followed by a full-text review to assess for eligibility. Data extraction was carried out in an online Excel sheet. Risk ratio (RR) and mean difference (MD) was used as the outcome measure for dichotomous and continuous outcomes, respectively. Comprehensive meta-analysis software (version 3) was used for statistical analysis. A p-value of .05 was deemed significant throughout the analysis.
This meta-analysis was registered on Prospero with the registration number “CRD42024524425.”
Tabulation, Integration, and Results
This meta-analysis comprised 12 studies: 8 randomized controlled trials (RCTs) and 4 non-RCTs with a total of population of 874 participants: 425 in the PRP group and 449 in the control group. Our meta-analysis showed that the PRP administration significantly improved the recurrence of moderate to severe adhesions (RR: 0.477, p-value: <.001), reduction in American Fertility Score (AFS) score (MD: 0.862, p-value: .043), clinical pregnancy rate (RR: 1.373, p-value = .036), menstruation flow (MD: 2.956, p-value: <.001), change in endometrial thickness (MD: 0.815, p-value <.001), and menstruation duration (MD: 1.132, p-value <.001). However, no significant difference was observed for chemical pregnancy, miscarriage, and live birth rate.
Conclusion
PRP shows promising results in reducing adhesion recurrence and has a potential to improve pregnancy outcomes. Further large-scale RCTs, particularly addressing dosage-response relationships, are needed to better understand the efficacy of PRP in preventing the recurrence of intrauterine adhesions.
{"title":"Does Platelet-Rich Plasma Improve Adhesion Recurrence and Pregnancy Outcomes in Women With Intrauterine Adhesions? A Systematic Review and Meta-Analysis","authors":"Gaofa Wang PhD, Yuanjun Zhu MD, Na Duan BSN, Chong Guo PhD, Nannan Liu BSN, Hanling Huang MD","doi":"10.1016/j.jmig.2024.10.013","DOIUrl":"10.1016/j.jmig.2024.10.013","url":null,"abstract":"<div><h3>Objective</h3><div>To determine the role of Platelet-rich plasma (PRP) in improving pregnancy and adhesion recurrence outcomes in women who underwent hysteroscopic treatment of intrauterine adhesions.</div></div><div><h3>Data Sources</h3><div>A total of 3 databases: Google scholar, PubMed, and clinicaltrials.gov were searched extensively from inception until April 5, 2023, without any language restrictions.</div></div><div><h3>Methods of Study selection</h3><div>After the removal of duplicates, studies were first scrutinized on the basis of title/abstract followed by a full-text review to assess for eligibility. Data extraction was carried out in an online Excel sheet. Risk ratio (RR) and mean difference (MD) was used as the outcome measure for dichotomous and continuous outcomes, respectively. Comprehensive meta-analysis software (version 3) was used for statistical analysis. A p-value of .05 was deemed significant throughout the analysis.</div><div>This meta-analysis was registered on Prospero with the registration number “CRD42024524425.”</div></div><div><h3>Tabulation, Integration, and Results</h3><div>This meta-analysis comprised 12 studies: 8 randomized controlled trials (RCTs) and 4 non-RCTs with a total of population of 874 participants: 425 in the PRP group and 449 in the control group. Our meta-analysis showed that the PRP administration significantly improved the recurrence of moderate to severe adhesions (RR: 0.477, p-value: <.001), reduction in American Fertility Score (AFS) score (MD: 0.862, p-value: .043), clinical pregnancy rate (RR: 1.373, p-value = .036), menstruation flow (MD: 2.956, p-value: <.001), change in endometrial thickness (MD: 0.815, p-value <.001), and menstruation duration (MD: 1.132, p-value <.001). However, no significant difference was observed for chemical pregnancy, miscarriage, and live birth rate.</div></div><div><h3>Conclusion</h3><div>PRP shows promising results in reducing adhesion recurrence and has a potential to improve pregnancy outcomes. Further large-scale RCTs, particularly addressing dosage-response relationships, are needed to better understand the efficacy of PRP in preventing the recurrence of intrauterine adhesions.</div></div>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":"32 2","pages":"Pages 133-142.e7"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}