Introduction: Advances in new communication technologies have created a good environment for the provision of various services. Due to the importance of using new communication technologies in health care, this study was conducted to identify opportunities, threats, strengths, and weaknesses of these technologies in the field of health with a focus on rare patients. Method: This qualitative study was conducted with the participation of 40 experts and specialists in the field of communication and health, and a number of rare patients. The sampling method was snowball sampling and semi-structured interviews continued to the point of data saturation. To collect data, notes were taken and the interviews were recorded and transcribed. For accurate data analysis, MAXQDA (version 12) was used. Results: The results of this study on opportunities, challenges, threatening factors, and strategies of using new communication technologies in the field of health led to the formation and identification of 379 initial codes, including 45 categories, which finally 4 themes of opportunities, threats, strengths, and weaknesses were extracted. Conclusion: New communication technologies, regarding their potentials, could facilitate the advancement of health communication and provide better digital solutions for rare patients, who face various challenges in their treatment period and social life, as well as mental and psychological concerns and the need for information. It is recommended to determine the potentials, difficulties, and barriers associated with employing new communication technologies and then, plan, establish standards and rules, and employ these technologies accordingly
{"title":"Identifying the Potentials, Challenges, and Barriers to the Application of New Communication Technologies in the Field of Health with a Focus on Rare Patients: A Qualitative Study","authors":"","doi":"10.32592/nkums.14.4.1","DOIUrl":"https://doi.org/10.32592/nkums.14.4.1","url":null,"abstract":"Introduction: Advances in new communication technologies have created a good environment for the provision of various services. Due to the importance of using new communication technologies in health care, this study was conducted to identify opportunities, threats, strengths, and weaknesses of these technologies in the field of health with a focus on rare patients.\u0000Method: This qualitative study was conducted with the participation of 40 experts and specialists in the field of communication and health, and a number of rare patients. The sampling method was snowball sampling and semi-structured interviews continued to the point of data saturation. To collect data, notes were taken and the interviews were recorded and transcribed. For accurate data analysis, MAXQDA (version 12) was used.\u0000Results: The results of this study on opportunities, challenges, threatening factors, and strategies of using new communication technologies in the field of health led to the formation and identification of 379 initial codes, including 45 categories, which finally 4 themes of opportunities, threats, strengths, and weaknesses were extracted.\u0000Conclusion: New communication technologies, regarding their potentials, could facilitate the advancement of health communication and provide better digital solutions for rare patients, who face various challenges in their treatment period and social life, as well as mental and psychological concerns and the need for information. It is recommended to determine the potentials, difficulties, and barriers associated with employing new communication technologies and then, plan, establish standards and rules, and employ these technologies accordingly","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"2012 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73786547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: This study aimed to analyze the factors affecting the development of the quality of life of the elderly in North Khorasan Province emphasizing the role of participation in physical activities. Method: This study used a qualitative-quantitative research method. The statistical population in the qualitative section included a number of experts, such as sports officials of the province; professors of sports management, psychology, sociology, and geriatrics; as well as officials of welfare and health departments (n=25). In the quantitative section, the statistical population included a number of elderly referring to sports centers (n=247). A purposeful and convenience method was used for sampling. The required data were collected using interviews (in the qualitative section) and a researcher-made questionnaire (in the quantitative section). The validity of the questionnaire was confirmed by 8 experts. Data analysis was conducted using descriptive and inferential statistics in SPSS (version 21) and LISREL (version 8.7) software. Results: Based on the results, the most important factors affecting the elderly participation in physical activities and development of their quality of life were management strategies, advertising and noticing, financial and economic, personal, socio-cultural, places, and facilities. Conclusion: According to the findings of the study, managers should pay special attention to the factors affecting the participation of the elderly in sports activities and help improve their quality of life by providing suitable conditions for their participation in these activities.
{"title":"Analysis of Factors Affecting the Development of Quality of Life among the Elderly in North Khorasan Province Emphasizing the Role of Participation in Physical Activities","authors":"","doi":"10.32592/nkums.14.4.87","DOIUrl":"https://doi.org/10.32592/nkums.14.4.87","url":null,"abstract":"Introduction: This study aimed to analyze the factors affecting the development of the quality of life of the elderly in North Khorasan Province emphasizing the role of participation in physical activities. Method: This study used a qualitative-quantitative research method. The statistical population in the qualitative section included a number of experts, such as sports officials of the province; professors of sports management, psychology, sociology, and geriatrics; as well as officials of welfare and health departments (n=25). In the quantitative section, the statistical population included a number of elderly referring to sports centers (n=247). A purposeful and convenience method was used for sampling. The required data were collected using interviews (in the qualitative section) and a researcher-made questionnaire (in the quantitative section). The validity of the questionnaire was confirmed by 8 experts. Data analysis was conducted using descriptive and inferential statistics in SPSS (version 21) and LISREL (version 8.7) software. Results: Based on the results, the most important factors affecting the elderly participation in physical activities and development of their quality of life were management strategies, advertising and noticing, financial and economic, personal, socio-cultural, places, and facilities. Conclusion: According to the findings of the study, managers should pay special attention to the factors affecting the participation of the elderly in sports activities and help improve their quality of life by providing suitable conditions for their participation in these activities.","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"80 9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87992948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Semaphorin 3C (Sema3C) is a relatively new and lesser-known adipokine. Recent studies have demonstrated that the class 3 semaphorin subfamilies have the most significant role in metabolic disorders. Therefore, the present study aimed to investigate the effect of obesity on skeletal muscle Sema3C levels in male and female Wistar rats. Method: In this experimental study, 12 male and female 8-week-old Wistar rats with a mean weight of 138 ± 13.60 gr were randomly assigned to two groups of six: non-obese (three males and three females) and Obese (three males and three females). The rats were dissected after eight weeks of induction of obesity and 18-20 hours of fasting, and their skeletal muscle tissue was rapidly removed and frozen. The sema3C level of skeletal muscle was measured by ELISA. Data were analyzed in SPSS software (version 21) using a two-way ANOVA test at a significance level of P≤0.0. In addition, the effect of obesity intervention was investigated in male and female rats separately. Results: Based on the results of the present study, the level of Sema3C in male and female rats in the obese group increased; nonetheless, it was not significant (P≥0.05). Moreover, Lee's index did not change significantly in male and female rats in the obese group (P≥0.05). Conclusion: It seems that a high-fat diet increases the level of Sema3C in skeletal muscle which can have negative effects on the whole body system considering the role of this adipokine in the spread of metabolic diseases
{"title":"Effect of Obesity on Skeletal Muscle Semaphorin 3C Levels in Male and Female Wistar Rats","authors":"","doi":"10.32592/nkums.14.3.92","DOIUrl":"https://doi.org/10.32592/nkums.14.3.92","url":null,"abstract":"Introduction: Semaphorin 3C (Sema3C) is a relatively new and lesser-known adipokine. Recent studies have demonstrated that the class 3 semaphorin subfamilies have the most significant role in metabolic disorders. Therefore, the present study aimed to investigate the effect of obesity on skeletal muscle Sema3C levels in male and female Wistar rats.\u0000Method: In this experimental study, 12 male and female 8-week-old Wistar rats with a mean weight of 138 ± 13.60 gr were randomly assigned to two groups of six: non-obese (three males and three females) and Obese (three males and three females). The rats were dissected after eight weeks of induction of obesity and 18-20 hours of fasting, and their skeletal muscle tissue was rapidly removed and frozen. The sema3C level of skeletal muscle was measured by ELISA. Data were analyzed in SPSS software (version 21) using a two-way ANOVA test at a significance level of P≤0.0. In addition, the effect of obesity intervention was investigated in male and female rats separately.\u0000Results: Based on the results of the present study, the level of Sema3C in male and female rats in the obese group increased; nonetheless, it was not significant (P≥0.05). Moreover, Lee's index did not change significantly in male and female rats in the obese group (P≥0.05).\u0000Conclusion: It seems that a high-fat diet increases the level of Sema3C in skeletal muscle which can have negative effects on the whole body system considering the role of this adipokine in the spread of metabolic diseases","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90768367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: The reduction of inequality in the utilization of resources and facilities of society is considered one of the most important criteria of development. The present study aimed to investigate equality in the distribution of human resources in the health sector in North Khorasan province (by the Gini coefficient and Lorenz curve) in 2020. Method: This study was conducted based on a descriptive-analytical design. The study population included human resources in the health sector. Data were collected from the national portal of the Statistical Center of Iran and the population yearbook of the province using a researcher-made form. Data were analyzed in STATA (version 12) and DASP (version 2.2) software packages. Results: For every 10,000 people, 55.3 human resources were working in the health sector of North Khorasan province. Human health resources are distributed equally in this province. The Gini coefficient for all human health resources, except nurses and specialists, was less than 0.2, indicating complete equality in the distribution of resources. The lowest coefficient value was related to general practitioners (0.052), and the highest Gini coefficient pertained to specialized physicians (0.422), pointing to a relative inequality in the distribution of specialized physicians. Conclusion: The removal of inequalities in human resources in the health sector in different regions can result in the promotion of equality in health outcomes. Therefore, it is suggested that policymakers and senior health system managers take effective measures to improve justice in access to human resources
{"title":"Evaluation of Equality in the Distribution of Human Resources in the Health Sector of North Khorasan Province","authors":"","doi":"10.32592/nkums.14.3.84","DOIUrl":"https://doi.org/10.32592/nkums.14.3.84","url":null,"abstract":"Introduction: The reduction of inequality in the utilization of resources and facilities of society is considered one of the most important criteria of development. The present study aimed to investigate equality in the distribution of human resources in the health sector in North Khorasan province (by the Gini coefficient and Lorenz curve) in 2020.\u0000Method: This study was conducted based on a descriptive-analytical design. The study population included human resources in the health sector. Data were collected from the national portal of the Statistical Center of Iran and the population yearbook of the province using a researcher-made form. Data were analyzed in STATA (version 12) and DASP (version 2.2) software packages.\u0000Results: For every 10,000 people, 55.3 human resources were working in the health sector of North Khorasan province. Human health resources are distributed equally in this province. The Gini coefficient for all human health resources, except nurses and specialists, was less than 0.2, indicating complete equality in the distribution of resources. The lowest coefficient value was related to general practitioners (0.052), and the highest Gini coefficient pertained to specialized physicians (0.422), pointing to a relative inequality in the distribution of specialized physicians.\u0000Conclusion: The removal of inequalities in human resources in the health sector in different regions can result in the promotion of equality in health outcomes. Therefore, it is suggested that policymakers and senior health system managers take effective measures to improve justice in access to human resources","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"112 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90748279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Diabetes is currently the sixth cause of death and has no definitive cure. Therefore, it is essential to focus on patients’ awareness and education. This study aimed to determine the effectiveness of a specifically designed integrated web-based self-care protocol on health-related quality of life, mental well-being, and blood sugar in type 2 diabetic patients. Method: The present study followed a pretest-posttest design with a control group. Of patients with type 2 diabetes referred to the Diabetes Society of Tehran (Tehran, Iran), 64 were selected and randomly assigned to the two groups. The experimental group attended five one-hour treatment sessions on the Internet. Data were collected by administering the Self-Care Summary Questionnaire, Diabetes Dependent Quality of Life Scale, and Psychological Welfare Questionnaire before and after the treatment. Collected data were analyzed using Multivariate Analysis of Covariance (MANCOVA). Results: The results showed a significant difference between the two groups in the level of blood sugar (F=4.35), well-being (F=14.24), quality of life (F=52.63), and self-care (F=68.54) at the significance level of 0.001. Conclusion: Considering the importance of self-care education and mobile (virtual) health, it is recommended that web-based self-care treatments are utilized for controlling diabetes
{"title":"Effectiveness of an Integrated Web-Based Self-Care Protocol on Mental Well-Being, Quality of Life, and Blood Sugar in Patients with Type 2 Diabetes","authors":"","doi":"10.32592/nkums.14.3.59","DOIUrl":"https://doi.org/10.32592/nkums.14.3.59","url":null,"abstract":"Introduction: Diabetes is currently the sixth cause of death and has no definitive cure. Therefore, it is essential to focus on patients’ awareness and education. This study aimed to determine the effectiveness of a specifically designed integrated web-based self-care protocol on health-related quality of life, mental well-being, and blood sugar in type 2 diabetic patients.\u0000Method: The present study followed a pretest-posttest design with a control group. Of patients with type 2 diabetes referred to the Diabetes Society of Tehran (Tehran, Iran), 64 were selected and randomly assigned to the two groups. The experimental group attended five one-hour treatment sessions on the Internet. Data were collected by administering the Self-Care Summary Questionnaire, Diabetes Dependent Quality of Life Scale, and Psychological Welfare Questionnaire before and after the treatment. Collected data were analyzed using Multivariate Analysis of Covariance (MANCOVA).\u0000Results: The results showed a significant difference between the two groups in the level of blood sugar (F=4.35), well-being (F=14.24), quality of life (F=52.63), and self-care (F=68.54) at the significance level of 0.001.\u0000Conclusion: Considering the importance of self-care education and mobile (virtual) health, it is recommended that web-based self-care treatments are utilized for controlling diabetes","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90370325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Diagnosis of cancer is very distressing and causes a lack of control and insecurity in the suffering person. Resilience and self-efficacy are two essential support factors that can help these people; therefore, the present study aimed to compare the effectiveness of mindfulness-based schema therapy and transdiagnostic intervention in women with breast cancer on cancer self-efficacy and resilience along with a follow-up period. Method: The research method was quasi-experimental with a pretest-posttest design and a follow-up period of 45 days. The statistical population included female patients with breast cancer in 2019-2022 referred to Omid and Imam Reza hospitals in Mashhad, Iran. The instruments were the Cancer Self-efficacy Questionnaire of Champion et al. (2013) and the Cancer Resilience Questionnaire of Sonaga and Futavatari (2018). In total, 41 subjects were purposefully selected from the population and randomly assigned to the experimental and control groups. For the two experimental groups, the intervention was performed for 10 weekly sessions. Data analysis was performed using the repeated measures analysis of variance (ANOVA) test and Bonferroni post hoc test using the SPSS statistical software (version 25) at the significance level of 0.05. Results: There was a significant difference between the mean scores of the first and second experimental groups and the control group in the post-test and follow-up concerning resilience (P<0.007) and self-efficacy (P<0.01). On the other hand, there was no significant difference between transdiagnostic effectiveness and mindfulness-based schema therapy in the post-test and follow-up (P>0.05). Conclusion: Based on the present findings, it is suggested to reduce the psychological problems of women with breast cancer through mindfulness-based schema therapy and transdiagnostic treatment
简介:癌症的诊断是非常痛苦的，导致患者缺乏控制和不安全感。弹性和自我效能是两个重要的支持因素，可以帮助这些人;因此，本研究旨在比较基于正念的图式治疗和跨诊断干预对乳腺癌女性癌症自我效能感和恢复力的影响，并进行随访。方法:采用准实验研究方法，采用前测后测设计，随访45 d。统计人群包括2019-2022年在伊朗马什哈德的奥米德和伊玛目礼萨医院转诊的女性乳腺癌患者。研究工具为Champion et al.(2013)的癌症自我效能问卷和Sonaga and Futavatari(2018)的癌症弹性问卷。总共从人群中有目的地选择了41名受试者，并随机分配到实验组和对照组。对于两个实验组，干预进行了10周的会议。数据分析采用重复测量方差分析(ANOVA)检验和Bonferroni事后检验，采用SPSS统计软件(版本25)，显著性水平为0.05。结果:第一、第二实验组与对照组在心理弹性后测及随访中的平均得分差异有统计学意义(P0.05)。结论:基于本研究结果，建议通过正念图式疗法和跨诊断治疗来减少乳腺癌妇女的心理问题
{"title":"Effectiveness of Transdiagnostic Intervention and Mindfulness-Based Schema Therapy on Cancer Self-Efficacy and Resilience in Women with Breast Cancer","authors":"","doi":"10.32592/nkums.14.3.24","DOIUrl":"https://doi.org/10.32592/nkums.14.3.24","url":null,"abstract":"Introduction: Diagnosis of cancer is very distressing and causes a lack of control and insecurity in the suffering person. Resilience and self-efficacy are two essential support factors that can help these people; therefore, the present study aimed to compare the effectiveness of mindfulness-based schema therapy and transdiagnostic intervention in women with breast cancer on cancer self-efficacy and resilience along with a follow-up period.\u0000Method: The research method was quasi-experimental with a pretest-posttest design and a follow-up period of 45 days. The statistical population included female patients with breast cancer in 2019-2022 referred to Omid and Imam Reza hospitals in Mashhad, Iran. The instruments were the Cancer Self-efficacy Questionnaire of Champion et al. (2013) and the Cancer Resilience Questionnaire of Sonaga and Futavatari (2018). In total, 41 subjects were purposefully selected from the population and randomly assigned to the experimental and control groups. For the two experimental groups, the intervention was performed for 10 weekly sessions. Data analysis was performed using the repeated measures analysis of variance (ANOVA) test and Bonferroni post hoc test using the SPSS statistical software (version 25) at the significance level of 0.05.\u0000Results: There was a significant difference between the mean scores of the first and second experimental groups and the control group in the post-test and follow-up concerning resilience (P<0.007) and self-efficacy (P<0.01). On the other hand, there was no significant difference between transdiagnostic effectiveness and mindfulness-based schema therapy in the post-test and follow-up (P>0.05).\u0000Conclusion: Based on the present findings, it is suggested to reduce the psychological problems of women with breast cancer through mindfulness-based schema therapy and transdiagnostic treatment","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89627054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Research efforts for early prediction of COVID-19 are still ongoing. This study aimed to introduce an index for predicting lung involvement in hypertensive patients with COVID-19. Method: All hypertensive patients with COVID-19 who were hospitalized in the intensive care unit of Imam Sajjad Hospital in Tabriz, Iran, from February 1400 to May 1401 comprised the statistical population of this study, who were selected as the statistical sample by the census. The vitamin D concentration, C-reactive protein, and L-cysteine levels in serum were determined by the ELISA technique. An independent t-test was used to analyze the differences between groups. In addition, the C-reactive protein to L-cysteine ratio was calculated in both groups. A P-value of less than 0.05 was considered statistically significant. Results: All hypertensive patients with COVID-19 admitted to the intensive care unit had lung involvement of > 50% and vitamin D deficiency of < 20 ng/ml. The Vitamin D concentration was > 26 ng/ml in healthy individuals. The findings showed hypertensive patients with COVID-19 had significantly higher levels of C-reactive protein, L-cysteine, and C-reactive protein to L-cysteine ratio than healthy individuals (P≤0.005). Conclusion: The ratio of C-reactive protein to L-cysteine and vitamin D deficiency could better predict lung involvement in hypertensive patients with COVID-19
导言:COVID-19的早期预测研究仍在进行中。本研究旨在建立一种预测高血压合并COVID-19患者肺部病变的指标。方法:1400年2月至1401年5月在伊朗大不里士市伊玛目萨贾德医院重症监护室住院的所有COVID-19高血压患者构成本研究的统计人群，采用人口普查的方法选择这些患者作为统计样本。采用ELISA法测定血清维生素D浓度、c反应蛋白和l -半胱氨酸水平。采用独立t检验分析组间差异。计算两组大鼠c反应蛋白与l -半胱氨酸的比值。p值小于0.05被认为具有统计学意义。结果:所有入住重症监护室的高血压合并COVID-19患者肺部受累> 50%，维生素D缺乏症< 20 ng/ml。健康个体维生素D浓度> 26 ng/ml。结果显示，高血压合并COVID-19患者c -反应蛋白、l -半胱氨酸水平及c -反应蛋白/ l -半胱氨酸比值均显著高于健康人群(P≤0.005)。结论:c反应蛋白/ l -半胱氨酸比值和维生素D缺乏可更好地预测COVID-19高血压患者肺部病变
{"title":"Introducing an Index to Predict Lung Involvement in Hypertensive Patients with COVID-19","authors":"","doi":"10.32592/nkums.14.3.78","DOIUrl":"https://doi.org/10.32592/nkums.14.3.78","url":null,"abstract":"Introduction: Research efforts for early prediction of COVID-19 are still ongoing. This study aimed to introduce an index for predicting lung involvement in hypertensive patients with COVID-19.\u0000Method: All hypertensive patients with COVID-19 who were hospitalized in the intensive care unit of Imam Sajjad Hospital in Tabriz, Iran, from February 1400 to May 1401 comprised the statistical population of this study, who were selected as the statistical sample by the census. The vitamin D concentration, C-reactive protein, and L-cysteine levels in serum were determined by the ELISA technique. An independent t-test was used to analyze the differences between groups. In addition, the C-reactive protein to L-cysteine ratio was calculated in both groups. A P-value of less than 0.05 was considered statistically significant.\u0000Results: All hypertensive patients with COVID-19 admitted to the intensive care unit had lung involvement of > 50% and vitamin D deficiency of < 20 ng/ml. The Vitamin D concentration was > 26 ng/ml in healthy individuals. The findings showed hypertensive patients with COVID-19 had significantly higher levels of C-reactive protein, L-cysteine, and C-reactive protein to L-cysteine ratio than healthy individuals (P≤0.005).\u0000Conclusion: The ratio of C-reactive protein to L-cysteine and vitamin D deficiency could better predict lung involvement in hypertensive patients with COVID-19","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"84 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83933070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: The present study aimed to compare the effect of high-intensity interval training (HIIT), sleep regulation, and the combined method on interleukin-6 (IL-6), high-sensitivity reactive protein (hs-CRP), anaerobic capacity, and body mass index (BMI) of adolescent girls with sleep disorders. Method: Eighty teenage girls with sleep disorders were randomly assigned to HIIT, sleep regulation, a combination of the two (HIIT+ sleep regulation), and control groups. All girls participated in pre-test and post-test sessions for the measurements two days before and after the research process. The participants in the HIIT and combined groups underwent a HIIT training program for four weeks, three sessions per week, and the subjects in the sleep regulation and combined groups performed the sleep regulation program by extending the sleep time duration by five minutes every night. Results: The findings showed a significant difference between groups for the serum levels of IL-6 and hs-CRP, BMI, and anaerobic power (P<0.001). Bonferroni's post hoc test showed a significant decrease in BMI and serum levels of IL-6 and hs-CRP and a significant increase in the minimum power in the combined group compared to the other three groups (P<0.001). In addition, a significant increase in anaerobic power (peak and average power) was respectively observed in the combined and HIIT groups, compared to the sleep regulation and control groups (P<0.001). Conclusion: The HIIT+ sleep regulation combined intervention can be a valuable interventional treatment to improve the care of sleep disorders in adolescent girls and, consequently, reduce the problems and costs of treatment for these individuals and their families
{"title":"The Effect of High-Intensity Interval Training and Sleep Regulation on Some Inflammatory Markers, Anaerobic Capacity, and Body Composition in Teenage Girls with Sleep Disorders","authors":"","doi":"10.32592/nkums.14.3.16","DOIUrl":"https://doi.org/10.32592/nkums.14.3.16","url":null,"abstract":"Introduction: The present study aimed to compare the effect of high-intensity interval training (HIIT), sleep regulation, and the combined method on interleukin-6 (IL-6), high-sensitivity reactive protein (hs-CRP), anaerobic capacity, and body mass index (BMI) of adolescent girls with sleep disorders.\u0000Method: Eighty teenage girls with sleep disorders were randomly assigned to HIIT, sleep regulation, a combination of the two (HIIT+ sleep regulation), and control groups. All girls participated in pre-test and post-test sessions for the measurements two days before and after the research process. The participants in the HIIT and combined groups underwent a HIIT training program for four weeks, three sessions per week, and the subjects in the sleep regulation and combined groups performed the sleep regulation program by extending the sleep time duration by five minutes every night.\u0000Results: The findings showed a significant difference between groups for the serum levels of IL-6 and hs-CRP, BMI, and anaerobic power (P<0.001). Bonferroni's post hoc test showed a significant decrease in BMI and serum levels of IL-6 and hs-CRP and a significant increase in the minimum power in the combined group compared to the other three groups (P<0.001). In addition, a significant increase in anaerobic power (peak and average power) was respectively observed in the combined and HIIT groups, compared to the sleep regulation and control groups (P<0.001).\u0000Conclusion: The HIIT+ sleep regulation combined intervention can be a valuable interventional treatment to improve the care of sleep disorders in adolescent girls and, consequently, reduce the problems and costs of treatment for these individuals and their families","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"94 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85701576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Moghaddasi, A. Moazedi, Z. Ghotbeddin, M. R. Akhond
{"title":"Study of the Combined Effect of Low Frequency Stimulation and Carbamazepine on Motor and Balance Behavior Indices during Unilateral Kindling in the CA1 Region of the Dorsal Hippocampus in Adult Male Rats","authors":"R. Moghaddasi, A. Moazedi, Z. Ghotbeddin, M. R. Akhond","doi":"10.52547/nkums.14.2.66","DOIUrl":"https://doi.org/10.52547/nkums.14.2.66","url":null,"abstract":"","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86831043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Salehi, M. Korani, M. Jafari, M. Izadi, A. Khonche
{"title":"The Effect of Different Ozone Concentrations on the Expression of β-catenin and HIF-I Genes in the Colon Tissue of BALB/c Mice Treated with Azoxymethane/dextran Sodium Sulfate","authors":"T. Salehi, M. Korani, M. Jafari, M. Izadi, A. Khonche","doi":"10.52547/nkums.14.2.1","DOIUrl":"https://doi.org/10.52547/nkums.14.2.1","url":null,"abstract":"","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79225754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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