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Health-related quality of life and stigma in opioid dependence: Comparison between buprenorphine users and non-users. 阿片类药物依赖的健康相关生活质量和耻辱感:丁丙诺啡使用者和非使用者之间的比较。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-07-01 Epub Date: 2023-05-23 DOI: 10.25259/JNRP_109_2023
Rohit Garg, Aditi Singla, Rajnish Raj

Objectives: Opioid dependence leads to reduced quality of life (QOL) and stigma. There is scarcity of literature on impact of buprenorphine on QOL of patients with opioid dependence from India. This study reports QOL and stigma in patients taking buprenorphine and compare it with those who were not on any treatment.

Materials and methods: A cross-sectional, descriptive, comparative study was conducted among three groups (n = 100 each). Group 3 comprised patients who were already taking buprenorphine for at least 3 months from a government outpatient opioid-assisted treatment center. Group 2 comprised patients who were not on any treatment but had come to enrol in buprenorphine treatment and Group 1 comprised patients who had come to get some other treatment and were not willing for buprenorphine. After fulfilling inclusion and exclusion criteria, sociodemographic pro forma, Hindi self-stigma scale, and World Health Organization QOL-BREF Hindi were applied. Appropriate statistical analyses were done.

Results: Patients already taking buprenorphine had significantly better QOL and it improved as the duration of treatment increased. Patients on buprenorphine treatment had significantly lesser stigma than patients not already on treatment. Stigma negatively impacted QOL in the three groups.

Conclusion: QOL and factors affecting it should be an integral part of management of opioid dependence. Efforts should be made to enrol maximum number of patients in treatment to enhance their quality of life and reduce stigma.

目的:阿片类药物依赖导致生活质量下降和耻辱感。印度缺乏关于丁丙诺啡对阿片类药物依赖患者生活质量影响的文献。本研究报告了服用丁丙诺啡的患者的生活质量和耻辱感,并将其与未接受任何治疗的患者进行了比较。材料和方法:在三组(每组n=100)中进行横断面、描述性比较研究。第3组包括已经在政府门诊阿片类药物辅助治疗中心服用丁丙诺啡至少3个月的患者。第2组包括未接受任何治疗但已开始接受丁丙诺啡治疗的患者,第1组包括接受其他治疗但不愿意接受丁丙诺啡的患者。在满足纳入和排除标准后,应用社会人口学形式、印地语自我污名量表和世界卫生组织QOL-BREF印地语。进行了适当的统计分析。结果:已经服用丁丙诺啡的患者生活质量显著改善,并且随着治疗时间的延长而改善。接受丁丙诺啡治疗的患者比未接受治疗的患者耻辱感明显减轻。污名对三组患者的生活质量产生负面影响。结论:生活质量及其影响因素应作为阿片类药物依赖管理的组成部分。应努力让最大数量的患者接受治疗,以提高他们的生活质量并减少耻辱感。
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引用次数: 0
Unexpected polyuria in a neurosurgical patient undergoing cerebellopontine angle tumor surgery: Can dexmedetomidine be the culprit? 一位接受桥小脑角肿瘤手术的神经外科患者意外多尿:右美托咪定会是罪魁祸首吗?
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-07-01 Epub Date: 2023-07-19 DOI: 10.25259/JNRP_156_2023
Somsubhra Pal, Vinitha Narayan, Apoorva Singh, Shalvi Mahajan
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引用次数: 0
Traumatic brain injury in college students and the influence of alcohol consumption: A retrospective review from a rural state. 大学生创伤性脑损伤与饮酒的影响:一项来自农村州的回顾性综述。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-04-01 Epub Date: 2023-03-16 DOI: 10.25259/JNRP_64_2022
Sonia Chandi, Patricia Dekeseredy, Nicholas J Brandmeir, Wei Fang, Cara L Sedney

Objectives: There is a strong association between alcohol consumption and traumatic brain injury (TBI). Students are known to consume alcohol at a high rate. Despite the connection between alcohol and TBI, this is one of few studies to examine the connection between students, alcohol, and TBI. The objective of this study was to explore the relationship between students, alcohol, and TBI.

Materials and methods: A retrospective chart review utilizing the institutional trauma data back was performed for patients 18-26 years of age, admitted to the emergency department with a diagnosis of a TBI and positive blood alcohol. Patient diagnosis, injury mechanism, alcohol level on admission, urine drug screen, mortality, injury severity score, and discharge disposition were recorded. The data were analyzed using Wilcoxon rank-sum tests and Chi-square tests to identify differences between students and non-student groups.

Results: Six hundred and thirty-six charts were reviewed for patients aged 18-26 with a positive blood alcohol level and TBI. The sample included 186 students, 209 non-students, and 241 uncertain of status. The student group had significantly higher levels of alcohol than the non-student group (P < 0.0001). P < 0.0001 showed that overall alcohol levels for males are significantly higher than levels of alcohol for females in the student group.

Conclusion: Alcohol consumption contributes to significant injuries such as TBI in college students. Male students had a higher prevalence of TBI, and higher alcohol levels than female students. These results can be used to inform and better target harm reduction and alcohol awareness programs.

目的:饮酒与创伤性脑损伤(TBI)之间有很强的相关性。众所周知,学生饮酒率很高。尽管酒精与TBI之间存在联系,但这是为数不多的研究学生、酒精和TBI之间的联系的研究之一。本研究的目的是探讨学生、酒精和创伤性脑损伤之间的关系。材料和方法:利用机构创伤数据对18-26岁的患者进行回顾性图表审查,这些患者被诊断为创伤性脑损伤,血液酒精呈阳性。记录患者诊断、损伤机制、入院时酒精水平、尿液药物筛查、死亡率、损伤严重程度评分和出院处置。使用Wilcoxon秩和检验和卡方检验对数据进行分析,以确定学生和非学生群体之间的差异。结果:对年龄在18-26岁且血液酒精水平和TBI呈阳性的患者的636张图表进行了回顾。样本包括186名学生、209名非学生和241名身份不确定的学生。学生组的酒精水平明显高于非学生组(P<0.0001)。P<0.0001表明,在学生组中,男性的总体酒精水平显著高于女性的酒精水平。结论:饮酒是导致大学生TBI等严重损伤的原因之一。男学生的TBI患病率高于女学生,酒精含量也高于女学生。这些结果可用于为减少伤害和酒精意识计划提供信息和更好的目标。
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引用次数: 0
Catatonia revealing a Fahr syndrome. 显示Fahr综合征的强直。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-04-01 Epub Date: 2023-03-16 DOI: 10.25259/JNRP_19_2023
Ferdaouss Qassimi, Saïd Boujraf, Ghizlane Lamgari, Assia Boukniter, Amine Bout, Chadya Aarab, Rachid Aalouane
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引用次数: 0
Results of a genetic study of children with Duchenne myodystrophy in Kazakhstan. 哈萨克斯坦Duchenne肌营养不良儿童的基因研究结果。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-04-01 Epub Date: 2023-04-26 DOI: 10.25259/JNRP_55_2022
Ainur Umurzakova, Dinmukhamed Ayaganov, Roza Nurgaliyeva
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引用次数: 0
Atretic cephaloceles with different imaging phenotypes - Case series with review of literature. 不同影像学表型的萎缩性头枕炎——病例系列及文献综述。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-04-01 Epub Date: 2023-03-16 DOI: 10.25259/JNRP_46_2022
Rajkumar Swathi Kiran, Vellathussery C Sunitha, Ravindar Kashyap, Ramachandran Madhan, Andi S Ramesh, Krishnan Nagarajan

Atretic cephaloceles (ACs) are congenital skull defects with herniation of rudimentary intracranial structures through the defect and associated with persistent falcine sinus or embryonic positioning of straight sinus. We describe five cases of ACs, out of which only one had embryonic straight sinus. Three cases had other intracranial malformations such as hypoplasia of corpus callosum, dysplastic tectum in one child and parieto-occipital polymicrogyria with falcotentorial dehiscence in the other, and frontal horn deformity and cortical dysplasia in the third. The prognosis of AC depends on the coexistent intracranial abnormalities and this highlights the role of magnetic resonance imaging in diagnosing the other associated anomalies for prediction of prognosis and planning of necessary surgical management.

萎缩性脑脊髓炎(ACs)是一种先天性颅骨缺陷,颅内基本结构通过该缺陷突出,并与持续的镰状窦或直窦的胚胎定位有关。我们描述了5例ACs,其中只有一例具有胚胎直窦。3例患者有其他颅内畸形,如胼胝体发育不全、顶盖发育异常,另一例有顶枕多显微回畸形伴镰裂,第三例有额角畸形和皮质发育不良。AC的预后取决于共存的颅内异常,这突出了磁共振成像在诊断其他相关异常以预测预后和计划必要的手术治疗中的作用。
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引用次数: 0
Spike wave complexes riding T-waves in generalized and focal pattern in two patients with hepatic encephalopathy. 两例肝性脑病患者的全身性和局灶性T波棘波复合体。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-04-01 Epub Date: 2023-02-23 DOI: 10.25259/JNRP_47_2022
Roshan Koul, Satyendra Kumar, Rakhi Maiwall
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引用次数: 0
A comparative analysis of demographic, clinical and imaging features of myelin oligodendrocyte glycoprotein antibody positive, aquaporin 4 antibody positive, and double seronegative demyelinating disorders - An Indian tertiary care center prospective study. 髓鞘少突胶质细胞糖蛋白抗体阳性、水通道蛋白4抗体阳性和双血清阴性脱髓鞘疾病的人口统计学、临床和影像学特征的比较分析——一项印度三级护理中心前瞻性研究。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-04-01 Epub Date: 2023-03-31 DOI: 10.25259/JNRP_32_2022
Manish Salunkhe, Pranjal Gupta, Rajesh Kumar Singh, Arunmozhimaran Elavarasi, Deepti Vibha, Ajay Garg, Rohit Bhatia, Manjari Tripathi

Objectives: The aim of the study was to study the demographical, clinical, radiological features, and outcome of anti-myelin oligodendrocyte glycoprotein (MOG) antibody spectrum disorder and compare these features with patients negative for anti-MOG antibody. MOG antibody-associated disease (MOGAD) and aquaporin-4 (AQP4) antibody-related diseases are immunologically distinct pathologies. Our aim was to compare the clinical and radiological features of MOG antibody-related diseases with AQP4 antibody-related diseases and seronegative demyelinating diseases (Non-multiple sclerosis).

Materials and methods: This was a prospective and cohort study conducted at an apex tertiary care institute in the northern part of India from Jan 2019 to May 2021. We compared clinical, laboratory, and radiological findings of patients with MOGAD, AQP4 antibody-related diseases, and seronegative demyelinating disease.

Results: There were a total of 103 patients - 41 patients of MOGAD, 37 patients of AQP4 antibody-related diseases and 25 seronegative demyelinating disease. Bilateral optic neuritis was the most frequent phenotype in patients with MOGAD (18/41) whereas myelitis was the most common phenotype in the AQP4 (30/37) and seronegative groups (13/25). Cortical, juxtacortical lesions, anterior segment optic neuritis, optic sheath enhancement, and conus involvement in myelitis were radiological findings that separated MOGAD from AQP4 related diseases. Nadir Expanded Disability Status Scale (EDSS) and visual acuity were similar across the groups. Last follow-up EDSS was significantly better in the MOG antibody group as compared to AQP4 antibody group (1 [0-8] vs. 3.5 [0-8]; P = 0.03). Encephalitis, myelitis, and seizures were more common in the younger population (<18 vs. >18 years) in MOGAD (9 vs. 2, P = 0.001; 9 vs. 7, P = 0.03; 6 vs. 0, P = 0.001).

Conclusion: We identified several clinical and radiological features that can help physicians to distinguish MOGAD from AQP4-immunoglobulin G+neuromyelitis optica spectrum disorder. Differentiation is vital as treatment response might vary among both groups.

目的:本研究的目的是研究抗髓鞘少突胶质细胞糖蛋白(MOG)抗体谱障碍的人口学、临床、放射学特征和结果,并将这些特征与抗MOG抗体阴性患者进行比较。MOG抗体相关疾病(MOGAD)和水通道蛋白-4(AQP4)抗体相关疾病是免疫学上不同的病理。我们的目的是比较MOG抗体相关疾病与AQP4抗体相关疾病和血清阴性脱髓鞘疾病(非多发性硬化症)的临床和放射学特征。材料和方法:这是一项前瞻性队列研究,于2019年1月至2021年5月在印度北部的一家顶尖三级护理机构进行。我们比较了MOGAD、AQP4抗体相关疾病和血清阴性脱髓鞘疾病患者的临床、实验室和放射学结果。结果:共有103例患者,其中MOGAD 41例,AQP4抗体相关疾病37例,血清阴性脱髓鞘疾病25例。双侧视神经炎是MOGAD患者最常见的表型(18/41),而脊髓炎是AQP4(30/37)和血清阴性组(13/25)最常见的表现型。脊髓炎的皮质、脊髓旁病变、前段视神经炎、视鞘增强和圆锥受累是将MOGAD与AQP4相关疾病区分开来的放射学发现。Nadir扩展残疾状态量表(EDSS)和视力在各组之间相似。MOG抗体组的最后一次随访EDSS明显优于AQP4抗体组(1[0-8]对3.5[0-8];P=0.03),癫痫发作在MOGAD的年轻人群(18岁)中更常见(9对2,P=0.001;9对7,P=0.03;6对0,P=0.001)。结论:我们确定了一些临床和放射学特征,可以帮助医生区分MOGAD和AQP4免疫球蛋白G+视神经脊髓炎谱系障碍。区分是至关重要的,因为两组的治疗反应可能不同。
{"title":"A comparative analysis of demographic, clinical and imaging features of myelin oligodendrocyte glycoprotein antibody positive, aquaporin 4 antibody positive, and double seronegative demyelinating disorders - An Indian tertiary care center prospective study.","authors":"Manish Salunkhe,&nbsp;Pranjal Gupta,&nbsp;Rajesh Kumar Singh,&nbsp;Arunmozhimaran Elavarasi,&nbsp;Deepti Vibha,&nbsp;Ajay Garg,&nbsp;Rohit Bhatia,&nbsp;Manjari Tripathi","doi":"10.25259/JNRP_32_2022","DOIUrl":"10.25259/JNRP_32_2022","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the study was to study the demographical, clinical, radiological features, and outcome of anti-myelin oligodendrocyte glycoprotein (MOG) antibody spectrum disorder and compare these features with patients negative for anti-MOG antibody. MOG antibody-associated disease (MOGAD) and aquaporin-4 (AQP4) antibody-related diseases are immunologically distinct pathologies. Our aim was to compare the clinical and radiological features of MOG antibody-related diseases with AQP4 antibody-related diseases and seronegative demyelinating diseases (Non-multiple sclerosis).</p><p><strong>Materials and methods: </strong>This was a prospective and cohort study conducted at an apex tertiary care institute in the northern part of India from Jan 2019 to May 2021. We compared clinical, laboratory, and radiological findings of patients with MOGAD, AQP4 antibody-related diseases, and seronegative demyelinating disease.</p><p><strong>Results: </strong>There were a total of 103 patients - 41 patients of MOGAD, 37 patients of AQP4 antibody-related diseases and 25 seronegative demyelinating disease. Bilateral optic neuritis was the most frequent phenotype in patients with MOGAD (18/41) whereas myelitis was the most common phenotype in the AQP4 (30/37) and seronegative groups (13/25). Cortical, juxtacortical lesions, anterior segment optic neuritis, optic sheath enhancement, and conus involvement in myelitis were radiological findings that separated MOGAD from AQP4 related diseases. Nadir Expanded Disability Status Scale (EDSS) and visual acuity were similar across the groups. Last follow-up EDSS was significantly better in the MOG antibody group as compared to AQP4 antibody group (1 [0-8] vs. 3.5 [0-8]; <i>P</i> = 0.03). Encephalitis, myelitis, and seizures were more common in the younger population (<18 vs. >18 years) in MOGAD (9 vs. 2, <i>P</i> = 0.001; 9 vs. 7, <i>P</i> = 0.03; 6 vs. 0, <i>P</i> = 0.001).</p><p><strong>Conclusion: </strong>We identified several clinical and radiological features that can help physicians to distinguish MOGAD from AQP4-immunoglobulin G+neuromyelitis optica spectrum disorder. Differentiation is vital as treatment response might vary among both groups.</p>","PeriodicalId":16443,"journal":{"name":"Journal of Neurosciences in Rural Practice","volume":"14 2","pages":"313-319"},"PeriodicalIF":1.4,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174118/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9461946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MRI of wrist and diffusion tensor imaging of the median nerve in patients with carpal tunnel syndrome. 腕管综合征患者手腕MRI和正中神经扩散张量成像。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-04-01 Epub Date: 2023-03-16 DOI: 10.25259/JNRP_57_2022
Suprava Naik, Siladitya Mahanty, Sanjeev Kumar Bhoi, Yuvraj Lahre, Nerbadyswari Deep Bag, Sudipta Mohakud

Objectives: Diagnosis of carpal tunnel syndrome (CTS) is based on the clinical symptoms and nerve conduction study. Magnetic resonance imaging (MRI) is non-invasive objective tool for assessing the median nerve and carpal tunnel. The purpose of this study was to evaluate MRI changes in patients with CTS, and compare them with healthy subjects.

Materials and methods: Forty-three CTS patients and 43 age matched control were included and scanned in a 3T MRI scanner. Cross-sectional areas (CSA) of median nerve were measured at the level of distal radio-ulnar joint level (CSA1), proximal row of carpal bone (CSA2), and hook of hamate (CSA3). Flattening ratio (FR) of median nerve, thickness of flexor retinaculum, median nerve signal intensity, and thenar muscles were assessed. Fractional anisotropy (FA), average diffusion coefficient (ADC), and radial diffusivity (RD) of median nerve of CTS patients were obtained from diffusion tensor imaging (DTI) and compared with those of controls.

Results: Thirty-three patients (76.7%) were female. Mean duration of the pain was 7.4 ± 2.6 months. The mean CSA1 (13.2 ± 4.2 mm2), CSA2 (12.5 ± 3.5 mm2), and CSA3 (9.2 ± 1.5 mm2) in CTS patients were significantly higher compared to control group: CSA1 (10.15 ± 1.64 mm2), CSA2 (9.38 ± 1.37 mm2), and CSA3 (8.4 ± 0.9 mm2), (P = 0.001 in all). The mean FR of median nerve and thickness of flexor retinaculum were increased in CTS patients. The mean FA was reduced in CTS patients compared to control proximal to carpal tunnel and within the tunnel. Mean ADC and RD values were higher in CTS patients as compared to control for both levels.

Conclusion: MRI can detect subtle changes in the median nerve and thenar muscles in CTS and may be useful in equivocal cases and to exclude secondary causes of CTS. DTI shows reduced FA and increased ADC and RD in CTS patients.

目的:腕管综合征的诊断是基于临床症状和神经传导研究。磁共振成像(MRI)是评估正中神经和腕管的非侵入性客观工具。本研究的目的是评估CTS患者的MRI变化,并将其与健康受试者进行比较。材料和方法:43名CTS患者和43名年龄匹配的对照组被纳入,并在3T MRI扫描仪中进行扫描。在桡尺关节远端(CSA1)、腕骨近端(CSA2)和钩钩(CSA3)水平测量正中神经的横截面积(CSA)。评估正中神经的展平率(FR)、屈肌支持带厚度、正中神经信号强度和鱼际肌。通过扩散张量成像(DTI)获得CTS患者正中神经的部分各向异性(FA)、平均扩散系数(ADC)和径向扩散率(RD),并与对照组进行比较。结果:33例(76.7%)为女性。疼痛的平均持续时间为7.4±2.6个月。CTS患者的平均CSA1(13.2±4.2 mm2)、CSA2(12.5±3.5 mm2)和CSA3(9.2±1.5 mm2)显著高于对照组:CSA1(10.15±1.64 mm2)、CSA 2(9.38±1.37 mm2)和CSA 3(8.4±0.9 mm2),(总体P=0.001)。CTS患者的正中神经平均FR和屈肌支持带厚度增加。与腕管近端和腕管内的对照组相比,CTS患者的平均FA降低。CTS患者的平均ADC和RD值均高于对照组。结论:MRI可以检测CTS中正中神经和大鱼际肌的细微变化,对于模棱两可的病例和排除CTS的次要原因可能有用。DTI显示CTS患者FA减少,ADC和RD增加。
{"title":"MRI of wrist and diffusion tensor imaging of the median nerve in patients with carpal tunnel syndrome.","authors":"Suprava Naik,&nbsp;Siladitya Mahanty,&nbsp;Sanjeev Kumar Bhoi,&nbsp;Yuvraj Lahre,&nbsp;Nerbadyswari Deep Bag,&nbsp;Sudipta Mohakud","doi":"10.25259/JNRP_57_2022","DOIUrl":"10.25259/JNRP_57_2022","url":null,"abstract":"<p><strong>Objectives: </strong>Diagnosis of carpal tunnel syndrome (CTS) is based on the clinical symptoms and nerve conduction study. Magnetic resonance imaging (MRI) is non-invasive objective tool for assessing the median nerve and carpal tunnel. The purpose of this study was to evaluate MRI changes in patients with CTS, and compare them with healthy subjects.</p><p><strong>Materials and methods: </strong>Forty-three CTS patients and 43 age matched control were included and scanned in a 3T MRI scanner. Cross-sectional areas (CSA) of median nerve were measured at the level of distal radio-ulnar joint level (CSA1), proximal row of carpal bone (CSA2), and hook of hamate (CSA3). Flattening ratio (FR) of median nerve, thickness of flexor retinaculum, median nerve signal intensity, and thenar muscles were assessed. Fractional anisotropy (FA), average diffusion coefficient (ADC), and radial diffusivity (RD) of median nerve of CTS patients were obtained from diffusion tensor imaging (DTI) and compared with those of controls.</p><p><strong>Results: </strong>Thirty-three patients (76.7%) were female. Mean duration of the pain was 7.4 ± 2.6 months. The mean CSA1 (13.2 ± 4.2 mm<sup>2</sup>), CSA2 (12.5 ± 3.5 mm<sup>2</sup>), and CSA3 (9.2 ± 1.5 mm<sup>2</sup>) in CTS patients were significantly higher compared to control group: CSA1 (10.15 ± 1.64 mm<sup>2</sup>), CSA2 (9.38 ± 1.37 mm<sup>2</sup>), and CSA3 (8.4 ± 0.9 mm<sup>2</sup>), (<i>P</i> = 0.001 in all). The mean FR of median nerve and thickness of flexor retinaculum were increased in CTS patients. The mean FA was reduced in CTS patients compared to control proximal to carpal tunnel and within the tunnel. Mean ADC and RD values were higher in CTS patients as compared to control for both levels.</p><p><strong>Conclusion: </strong>MRI can detect subtle changes in the median nerve and thenar muscles in CTS and may be useful in equivocal cases and to exclude secondary causes of CTS. DTI shows reduced FA and increased ADC and RD in CTS patients.</p>","PeriodicalId":16443,"journal":{"name":"Journal of Neurosciences in Rural Practice","volume":"14 2","pages":"302-307"},"PeriodicalIF":1.4,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174157/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9469064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emotion regulation and social responsiveness in adults with autism spectrum disorder. 自闭症谱系障碍成年人的情绪调节和社会反应能力。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-04-01 Epub Date: 2023-03-04 DOI: 10.25259/JNRP_19_2022
Akanksha Roy, Farhat Jahan

Objectives: This study aimed to find out the relationship between emotion regulation (ER) and its domains with social responsiveness (SR) to investigate ER and its domains as predictors of SR.

Materials and methods: A sample of 60 male and female adults diagnosed by a professional with autism spectrum disorder (ASD) was studied with ER and its domains of RI or Cognitive Reappraisal, SI or Expressive Suppression and SR as variables. Tools used were Social Responsiveness Scale-2 (Adult, Relative/Other online form) and Emotion Regulation Questionnaire (ERQ).

Results: ERQ domain of Cognitive Reappraisal or RI was found to be negatively correlated with Social Responsiveness or SR but positively correlated with Expressive Suppression or SI domain with Pearson's r value of -0.662 for RI and of 0.275 for SI. Furthermore, RI and SI variables were found to be significantly negatively correlated with each other. Multiple regression analysis results showed R to be 0.666 and predictor variables explained 44.4% of the variance in the data since R square was found to be 0.444. The model was found to be a significant predictor of the variable SR, F (2, 57) = 22.76, P = 0.000.

Conclusion: The present study found that ASD adults with high or good SR engage in less cognitive reappraisal (RI) ER strategy and more in expressive suppression (SI) strategy of ER. Multiple regression analysis results suggest a good and strong relationship suggesting our model is a relatively good predictor of the outcome.

目的:本研究旨在找出情绪调节(ER)及其领域与社会反应性(SR)之间的关系,以研究ER及其领域作为SR的预测因素。材料和方法:对60名经专业人士诊断为自闭症谱系障碍(ASD)的男性和女性成年人进行了ER及其RI或认知再评价领域的研究,SI或表达抑制和SR作为变量。使用的工具是社会反应量表-2(成人、亲属/其他在线表格)和情绪调节问卷(ERQ)。结果:认知再评价或RI的ERQ域与社会反应或SR呈负相关,但与表达抑制或SI域呈正相关,RI的Pearson r值为-0.662,SI为0.275。此外,RI和SI变量之间存在显著的负相关。多元回归分析结果显示R为0.666,预测变量解释了数据中44.4%的方差,因为R平方为0.444。该模型被发现是变量SR的重要预测因子,F(2,57)=22.76,P=0.000。结论:本研究发现,SR高或良好的ASD成年人对ER的认知再评价(RI)策略较少,而对ER的表达抑制(SI)策略较多。多元回归分析结果表明,我们的模型是一个相对较好的结果预测因子。
{"title":"Emotion regulation and social responsiveness in adults with autism spectrum disorder.","authors":"Akanksha Roy,&nbsp;Farhat Jahan","doi":"10.25259/JNRP_19_2022","DOIUrl":"10.25259/JNRP_19_2022","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to find out the relationship between emotion regulation (ER) and its domains with social responsiveness (SR) to investigate ER and its domains as predictors of SR.</p><p><strong>Materials and methods: </strong>A sample of 60 male and female adults diagnosed by a professional with autism spectrum disorder (ASD) was studied with ER and its domains of RI or Cognitive Reappraisal, SI or Expressive Suppression and SR as variables. Tools used were Social Responsiveness Scale-2 (Adult, Relative/Other online form) and Emotion Regulation Questionnaire (ERQ).</p><p><strong>Results: </strong>ERQ domain of Cognitive Reappraisal or RI was found to be negatively correlated with Social Responsiveness or SR but positively correlated with Expressive Suppression or SI domain with Pearson's r value of -0.662 for RI and of 0.275 for SI. Furthermore, RI and SI variables were found to be significantly negatively correlated with each other. Multiple regression analysis results showed R to be 0.666 and predictor variables explained 44.4% of the variance in the data since R square was found to be 0.444. The model was found to be a significant predictor of the variable SR, F (2, 57) = 22.76, <i>P</i> = 0.000.</p><p><strong>Conclusion: </strong>The present study found that ASD adults with high or good SR engage in less cognitive reappraisal (RI) ER strategy and more in expressive suppression (SI) strategy of ER. Multiple regression analysis results suggest a good and strong relationship suggesting our model is a relatively good predictor of the outcome.</p>","PeriodicalId":16443,"journal":{"name":"Journal of Neurosciences in Rural Practice","volume":"14 2","pages":"276-279"},"PeriodicalIF":1.4,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174144/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9473488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Neurosciences in Rural Practice
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