首页 > 最新文献

Journal of Neurosciences in Rural Practice最新文献

英文 中文
Tuberculous subdural empyema mimicking chronic subdural hematoma. 类似慢性硬膜下血肿的结核性硬膜下积脓。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-07-01 Epub Date: 2023-05-20 DOI: 10.25259/JNRP_91_2023
V Soundappan, Krishnan Nagarajan, Vellathussery Chakkalakkoombil Sunitha
{"title":"Tuberculous subdural empyema mimicking chronic subdural hematoma.","authors":"V Soundappan, Krishnan Nagarajan, Vellathussery Chakkalakkoombil Sunitha","doi":"10.25259/JNRP_91_2023","DOIUrl":"10.25259/JNRP_91_2023","url":null,"abstract":"","PeriodicalId":16443,"journal":{"name":"Journal of Neurosciences in Rural Practice","volume":"14 3","pages":"554-555"},"PeriodicalIF":1.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483205/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10588151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Para-choreo-ballism due to pinealoma in an elderly lady. 一位上了年纪的女士因松果体瘤导致的舞蹈障碍。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-07-01 Epub Date: 2023-01-18 DOI: 10.25259/JNRP-2022-2-32
Amit Shankar Singh, Jeenendra Prakash Singhvi, Jaslovleen Kaur
{"title":"Para-choreo-ballism due to pinealoma in an elderly lady.","authors":"Amit Shankar Singh, Jeenendra Prakash Singhvi, Jaslovleen Kaur","doi":"10.25259/JNRP-2022-2-32","DOIUrl":"10.25259/JNRP-2022-2-32","url":null,"abstract":"","PeriodicalId":16443,"journal":{"name":"Journal of Neurosciences in Rural Practice","volume":"14 3","pages":"551-553"},"PeriodicalIF":1.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483206/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10570356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glycopyrrolate-induced polyuria: An unexpected side effect. 吡咯烷酸酯引起的多尿:一种意想不到的副作用。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-07-01 Epub Date: 2023-06-05 DOI: 10.25259/JNRP_73_2023
Sunil Kumar Behera, Abhishek Agarwal, Alok Singh, Vinay R Pandit, Pankaj Kumar Kannauje

Polyuria is urine output exceeding 3 L/d in adults, primarily due to solute and water diuresis. In a hospital setting, mannitol and diuretics commonly lead to polyuria. We have found an interesting association of polyuria with glycopyrrolate; to the best of our knowledge, no case is reported in the literature. Here, we are describing a case of Guillain-Barre Syndrome, which developed polyuria during the hospital stay, which was secondary to glycopyrrolate.

多尿症是指成年人的尿量超过3L/d,主要是由于溶质和水的利尿。在医院环境中,甘露醇和利尿剂通常会导致多尿。我们发现了多尿与格隆吡咯烷酸酯的有趣关联;据我们所知,文献中没有病例报告。在这里,我们描述了一例格林-巴利综合征,该综合征在住院期间出现多尿,继发于格隆溴铵。
{"title":"Glycopyrrolate-induced polyuria: An unexpected side effect.","authors":"Sunil Kumar Behera,&nbsp;Abhishek Agarwal,&nbsp;Alok Singh,&nbsp;Vinay R Pandit,&nbsp;Pankaj Kumar Kannauje","doi":"10.25259/JNRP_73_2023","DOIUrl":"10.25259/JNRP_73_2023","url":null,"abstract":"<p><p>Polyuria is urine output exceeding 3 L/d in adults, primarily due to solute and water diuresis. In a hospital setting, mannitol and diuretics commonly lead to polyuria. We have found an interesting association of polyuria with glycopyrrolate; to the best of our knowledge, no case is reported in the literature. Here, we are describing a case of Guillain-Barre Syndrome, which developed polyuria during the hospital stay, which was secondary to glycopyrrolate.</p>","PeriodicalId":16443,"journal":{"name":"Journal of Neurosciences in Rural Practice","volume":"14 3","pages":"525-527"},"PeriodicalIF":1.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10588148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical treatment of epilepsy - Initial experience from a comprehensive epilepsy program in coastal South India. 癫痫的外科治疗——南印度沿海地区综合癫痫项目的初步经验。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-07-01 Epub Date: 2023-06-16 DOI: 10.25259/JNRP_116_2023
Nisha Shenoy, Siddharth Srinivasan, Girish Menon, Radhakrishnan Kurupath

Objectives: The objectives of this study were to share our initial experience with epilepsy surgery and provide an overview on the surgical treatments of epilepsies.

Materials and methods: This was a retrospective analysis of the demographics and clinical and investigative features of patients who underwent epilepsy surgery between January 2016 and August 2021. Postoperative seizure outcome was categorized according to modified Engel's classification, and the minimum period of follow-up was 1 year.

Results: The study group included 30 patients with an age ranging from 6 years to 45 years (mean: 22.28 years, median: 20 years) and a male: female ratio of 20:10. The epilepsy duration before surgery ranged from 3 years to 32 years (median: 7 years). Majority of our patients underwent resective surgeries (28/30 = 93.3%), and disconnection procedures were done in two patients. This included one functional hemispherotomy and one posterior quadrantic disconnection. Temporal lobe resective surgery was the most common procedure (16/30 = 53.3%), followed by eight frontal lobe and two parietal lobe surgeries. Among resective surgeries, majority were lesional surgeries and the pathologies included mesial temporal sclerosis (4), dysembryoplastic neuroepithelial tumor (8), ganglioglioma (6), cavernoma (4), focal cortical dysplasia (2), gliosis (1), and one case of hypothalamic hamartoma. Intraoperative electrocorticography was used in all cases for optimizing surgical resection/disconnection. Nearly two-thirds of our patients (66.6%) had an Engel's Class I outcome, five patients had Engel's Class II outcome, three patients had Class III outcome, and one patient did not have any worthwhile improvement. Temporal lobe surgery patients had a better seizure outcome compared to extratemporal surgeries (84% vs. 74%). Overall, complications were minimal and short lasting, and comprised meningitis in three patients (5.6%) and transient worsening of hemiparesis following hemispherotomy in two patients. There was no mortality or long-lasting major morbidity in our patients.

Conclusion: In carefully selected patients with drug-resistant epilepsy, surgery offers an excellent chance of becoming seizure-free with significant improvement in overall quality of life. Majority of the common epilepsy surgery procedures can be performed through a multidisciplinary approach even in centers with limited resources.

目的:本研究的目的是分享我们在癫痫手术方面的初步经验,并提供癫痫手术治疗的概述。材料和方法:这是对2016年1月至2021年8月期间接受癫痫手术的患者的人口统计学、临床和调查特征的回顾性分析。根据改良Engel分类法对术后癫痫发作结果进行分类,最短随访期为1年。结果:研究组包括30名患者,年龄从6岁到45岁不等(平均值:22.28岁,中位数:20岁),男女比例为20:10。手术前癫痫持续时间为3年至32年(中位数:7年)。我们的大多数患者接受了切除手术(28/30=93.3%),两名患者进行了断开手术。其中包括一个功能性半球切开术和一个后象限断开术。颞叶切除手术是最常见的手术(16/30=53.3%),其次是8例额叶和2例顶叶手术。在切除手术中,大多数是病变性手术,病理包括内侧颞叶硬化症(4)、胚胎发育不良神经上皮瘤(8)、神经节胶质瘤(6)、海绵体瘤(4),局灶性皮质发育不良(2)、胶质增生症(1)和一例下丘脑错构瘤。所有病例均采用术中皮质电描记术来优化手术切除/断开。我们近三分之二的患者(66.6%)有Engel’s I级结果,五名患者有Engel‘s II级结果,三名患者有III级结果,一名患者没有任何值得改善的情况。与颞叶外手术相比,颞叶手术患者的癫痫发作结果更好(84%对74%)。总的来说,并发症很小,持续时间短,包括三名患者(5.6%)的脑膜炎和两名患者在半球切开术后偏瘫的短暂恶化。我们的患者没有死亡或长期的主要发病率。结论:在精心挑选的耐药癫痫患者中,手术提供了一个极好的机会,使其摆脱癫痫发作,并显著提高了整体生活质量。即使在资源有限的中心,大多数常见的癫痫手术也可以通过多学科的方法进行。
{"title":"Surgical treatment of epilepsy - Initial experience from a comprehensive epilepsy program in coastal South India.","authors":"Nisha Shenoy,&nbsp;Siddharth Srinivasan,&nbsp;Girish Menon,&nbsp;Radhakrishnan Kurupath","doi":"10.25259/JNRP_116_2023","DOIUrl":"10.25259/JNRP_116_2023","url":null,"abstract":"<p><strong>Objectives: </strong>The objectives of this study were to share our initial experience with epilepsy surgery and provide an overview on the surgical treatments of epilepsies.</p><p><strong>Materials and methods: </strong>This was a retrospective analysis of the demographics and clinical and investigative features of patients who underwent epilepsy surgery between January 2016 and August 2021. Postoperative seizure outcome was categorized according to modified Engel's classification, and the minimum period of follow-up was 1 year.</p><p><strong>Results: </strong>The study group included 30 patients with an age ranging from 6 years to 45 years (mean: 22.28 years, median: 20 years) and a male: female ratio of 20:10. The epilepsy duration before surgery ranged from 3 years to 32 years (median: 7 years). Majority of our patients underwent resective surgeries (28/30 = 93.3%), and disconnection procedures were done in two patients. This included one functional hemispherotomy and one posterior quadrantic disconnection. Temporal lobe resective surgery was the most common procedure (16/30 = 53.3%), followed by eight frontal lobe and two parietal lobe surgeries. Among resective surgeries, majority were lesional surgeries and the pathologies included mesial temporal sclerosis (4), dysembryoplastic neuroepithelial tumor (8), ganglioglioma (6), cavernoma (4), focal cortical dysplasia (2), gliosis (1), and one case of hypothalamic hamartoma. Intraoperative electrocorticography was used in all cases for optimizing surgical resection/disconnection. Nearly two-thirds of our patients (66.6%) had an Engel's Class I outcome, five patients had Engel's Class II outcome, three patients had Class III outcome, and one patient did not have any worthwhile improvement. Temporal lobe surgery patients had a better seizure outcome compared to extratemporal surgeries (84% vs. 74%). Overall, complications were minimal and short lasting, and comprised meningitis in three patients (5.6%) and transient worsening of hemiparesis following hemispherotomy in two patients. There was no mortality or long-lasting major morbidity in our patients.</p><p><strong>Conclusion: </strong>In carefully selected patients with drug-resistant epilepsy, surgery offers an excellent chance of becoming seizure-free with significant improvement in overall quality of life. Majority of the common epilepsy surgery procedures can be performed through a multidisciplinary approach even in centers with limited resources.</p>","PeriodicalId":16443,"journal":{"name":"Journal of Neurosciences in Rural Practice","volume":"14 3","pages":"488-494"},"PeriodicalIF":1.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10219154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fatigue, chronic fatigue syndrome and migraine: Intersecting the lines through a cross-sectional study in patients with episodic and chronic migraine. 疲劳、慢性疲劳综合征和偏头痛:通过对发作性和慢性偏头痛患者的横断面研究来交叉线。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-07-01 Epub Date: 2023-04-20 DOI: 10.25259/JNRP_63_2022
Hemant Kumar, Kamakshi Dhamija, Ashish Duggal, Geeta Anjum Khwaja, Sujata Roshan

Objectives: Fatigue is a common symptom occurring in a variety of disorders. Chronic fatigue syndrome (CFS) is characterized by debilitating fatigue as the core symptom. The risk of CFS is nearly 1.5 times higher in migraine while headaches have been reported in 59% of cases with CFS. However, details of its occurrence and severity remain largely unexplored. The primary objective of our study was to determine the occurrence and severity of fatigue and CFS in patients with episodic and chronic migraine. The secondary objectives were to define their relationship with other common comorbidities.

Materials and methods: 60 migraine patients (30 each, episodic [EM] and chronic migraine [CM]) were recruited from Neurology Outpatient Department, GIPMER a tertiary referral center in New Delhi, India. Patients' headache severity was analyzed using the Headache impact test-6 (HIT-6) score while fatigue and other migraine accompaniments were assessed using Fatigue severity scale (FSS), Chalder fatigue scale, CDC diagnostic criteria for CFS, American College of Rheumatology Diagnostic Criteria for fibromyalgia, Hamilton Depression Scale, the Generalized Anxiety Disorder 7-Item Scale, and Epworth sleepiness Scale (ESS). Comparative analysis was further done among migraine patients with and without fatigue and CFS.

Results: The mean HIT-6 score was significantly higher in CM versus EM. The CM group had a higher mean FSS score (47.87 vs. 37.3 in EM; P = 0.004), a percentage of patients with severe fatigue (60% vs. 20% in EM; P = 0.004), and a higher percentage of patients with pathological fatigue (83.3% vs. 63.3% in EM; P = 0.04). Around 23.33% of CM patients fulfilled the criteria of CFS. Fatigue correlated positively with severity, frequency, attack duration and chronicity of the migraine episodes, along with depression, anxiety, and excessive daytime sleepiness.

Conclusion: Fatigue and related comorbid disorders are significantly more common in CM than in EM, expanding the morbidity of the condition and underscores the need to address these accompanying symptoms for devising a holistic treatment plan.

目的:疲劳是发生在各种疾病中的常见症状。慢性疲劳综合征以衰弱性疲劳为核心症状。偏头痛患者患慢性疲劳综合征的风险高出近1.5倍,而据报道,59%的慢性疲劳综合症患者出现头痛。然而,其发生和严重程度的细节在很大程度上仍未被探索。我们研究的主要目的是确定发作性和慢性偏头痛患者疲劳和慢性疲劳综合征的发生率和严重程度。次要目的是确定它们与其他常见合并症的关系。材料和方法:60名偏头痛患者(发作性[EM]和慢性偏头痛[CM]各30名)从印度新德里的三级转诊中心GIPMER神经门诊部招募。使用头痛影响测试-6(HIT-6)评分分析患者的头痛严重程度,同时使用疲劳严重程度量表(FSS)、Chalder疲劳量表、CDC慢性疲劳综合征诊断标准、美国风湿病学会纤维肌痛诊断标准、汉密尔顿抑郁量表、广泛性焦虑症7项量表评估疲劳和其他偏头痛伴随症状,和Epworth嗜睡量表(ESS)。对伴有和不伴有疲劳和慢性疲劳综合征的偏头痛患者进行了进一步的比较分析。结果:CM组的平均HIT-6评分显著高于EM组。CM组的FSS平均评分较高(EM组为47.87分,EM组为37.3分;P=0.004),严重疲劳患者的比例较高(EM为60%对20%;P=0.004。疲劳和偏头痛发作的严重程度、频率、发作持续时间和慢性性,以及抑郁、焦虑和白天过度嗜睡呈正相关。结论:疲劳和相关的合并症在CM中比EM中更常见,这增加了疾病的发病率,并强调了解决这些伴随症状以制定整体治疗计划的必要性。
{"title":"Fatigue, chronic fatigue syndrome and migraine: Intersecting the lines through a cross-sectional study in patients with episodic and chronic migraine.","authors":"Hemant Kumar,&nbsp;Kamakshi Dhamija,&nbsp;Ashish Duggal,&nbsp;Geeta Anjum Khwaja,&nbsp;Sujata Roshan","doi":"10.25259/JNRP_63_2022","DOIUrl":"10.25259/JNRP_63_2022","url":null,"abstract":"<p><strong>Objectives: </strong>Fatigue is a common symptom occurring in a variety of disorders. Chronic fatigue syndrome (CFS) is characterized by debilitating fatigue as the core symptom. The risk of CFS is nearly 1.5 times higher in migraine while headaches have been reported in 59% of cases with CFS. However, details of its occurrence and severity remain largely unexplored. The primary objective of our study was to determine the occurrence and severity of fatigue and CFS in patients with episodic and chronic migraine. The secondary objectives were to define their relationship with other common comorbidities.</p><p><strong>Materials and methods: </strong>60 migraine patients (30 each, episodic [EM] and chronic migraine [CM]) were recruited from Neurology Outpatient Department, GIPMER a tertiary referral center in New Delhi, India. Patients' headache severity was analyzed using the Headache impact test-6 (HIT-6) score while fatigue and other migraine accompaniments were assessed using Fatigue severity scale (FSS), Chalder fatigue scale, CDC diagnostic criteria for CFS, American College of Rheumatology Diagnostic Criteria for fibromyalgia, Hamilton Depression Scale, the Generalized Anxiety Disorder 7-Item Scale, and Epworth sleepiness Scale (ESS). Comparative analysis was further done among migraine patients with and without fatigue and CFS.</p><p><strong>Results: </strong>The mean HIT-6 score was significantly higher in CM versus EM. The CM group had a higher mean FSS score (47.87 vs. 37.3 in EM; <i>P</i> = 0.004), a percentage of patients with severe fatigue (60% vs. 20% in EM; <i>P</i> = 0.004), and a higher percentage of patients with pathological fatigue (83.3% vs. 63.3% in EM; <i>P</i> = 0.04). Around 23.33% of CM patients fulfilled the criteria of CFS. Fatigue correlated positively with severity, frequency, attack duration and chronicity of the migraine episodes, along with depression, anxiety, and excessive daytime sleepiness.</p><p><strong>Conclusion: </strong>Fatigue and related comorbid disorders are significantly more common in CM than in EM, expanding the morbidity of the condition and underscores the need to address these accompanying symptoms for devising a holistic treatment plan.</p>","PeriodicalId":16443,"journal":{"name":"Journal of Neurosciences in Rural Practice","volume":"14 3","pages":"424-431"},"PeriodicalIF":1.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10212650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuromodulation of spinal reflex pathway for the treatment of detrusor overactivity by medial plantar nerve stimulation at surface of sole of foot in patients with spinal cord injury. 脊髓反射通路神经调控治疗脊髓损伤患者足底内侧跖神经刺激逼尿肌过度活动。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-07-01 Epub Date: 2023-08-16 DOI: 10.25259/JNRP_27_2023
Rajdeep Ojha, Abhinav Singh, Jacob George, Bobeena Rachel Chandy

Objectives: Suprasacral spinal cord lesions are prone to have neurogenic detrusor overactivity leading to urinary incontinence. Current medical management has known side-effects and often surgical managements are irreversible. Electrical stimulation to modulate spinal reflex pathway having same nerve root as urinary bladder is reported in the literature. This study aimed to reduce detrusor overactivity in patients with spinal cord injury (SCI) using surface electrical stimulation of medial plantar nerve at the sole of foot.

Materials and methods: Twenty adults with SCI having episode of at least 1 leak/day due to detrusor overactivity as diagnosed by cystometrogram (CMG), were on clean intermittent catheterization and ankle jerk was present consented for the study. Participants were asked to maintain bladder diary a week before and during 2 weeks of treatment. CMG was done on day-0 and day-14. cmcUroModul@tor®, an inhouse developed electrical stimulator was used for ½ h daily for period of 2 weeks. Patient satisfaction feedback questionnaire was taken on completion of treatment. CMG data were analyzed using Wilcoxon signed-ranked test while bladder diary was analyzed using binomial distribution. P < 0.05 was considered as statistically significant. Institutional Review Board (IRB) and ethics committee of Christian Medical College, Vellore, approved the study (CMC/IRB/11061).

Results: Statistical significant improvement in maximum detrusor pressure (P = 0.03) and cystometric capacity (P = 0.04) was observed. Of 20 subjects, 18 showed improvement in bladder diary.

Conclusion: Neuromodulation of medial plantar nerve at sole of foot by surface electrical stimulation is non-invasive, cost-effective, and alternative simple treatment modality for urinary incontinence due to detrusor overactivity.

目的:骶上脊髓病变易发生神经源性逼尿肌过度活动,导致尿失禁。目前的医疗管理有已知的副作用,而手术管理往往是不可逆转的。文献中报道了电刺激以调节具有与膀胱相同神经根的脊髓反射通路。本研究旨在通过足底内侧足底神经的表面电刺激来减少脊髓损伤(SCI)患者的逼尿肌过度活动。材料和方法:20名成人脊髓损伤患者,根据膀胱测量图(CMG)诊断,由于逼尿肌过度活动,每天至少发生1次渗漏,接受了干净的间歇性导管插入术,并同意进行踝关节扭伤的研究。参与者被要求在治疗前一周和治疗期间保持膀胱日记。CMG在第0天和第14天进行。cmcUroModul@tor®,一种内部开发的电刺激器,每天使用½小时,持续2周。在治疗结束时进行患者满意度反馈问卷调查。CMG数据采用Wilcoxon符号排序检验进行分析,膀胱日记采用二项式分布进行分析。P<0.05具有统计学意义。机构审查委员会(IRB)和Vellore基督教医学院伦理委员会批准了这项研究(CMC/IRB/11061)。结果:观察到最大逼尿肌压(P=0.03)和膀胱测量能力(P=0.04)的统计学显著改善。在20名受试者中,18人膀胱日记改善。结论:表面电刺激对足底内侧跖神经神经调控治疗逼尿肌过度活动性尿失禁是一种无创、经济有效、可替代的简单治疗方法。
{"title":"Neuromodulation of spinal reflex pathway for the treatment of detrusor overactivity by medial plantar nerve stimulation at surface of sole of foot in patients with spinal cord injury.","authors":"Rajdeep Ojha,&nbsp;Abhinav Singh,&nbsp;Jacob George,&nbsp;Bobeena Rachel Chandy","doi":"10.25259/JNRP_27_2023","DOIUrl":"10.25259/JNRP_27_2023","url":null,"abstract":"<p><strong>Objectives: </strong>Suprasacral spinal cord lesions are prone to have neurogenic detrusor overactivity leading to urinary incontinence. Current medical management has known side-effects and often surgical managements are irreversible. Electrical stimulation to modulate spinal reflex pathway having same nerve root as urinary bladder is reported in the literature. This study aimed to reduce detrusor overactivity in patients with spinal cord injury (SCI) using surface electrical stimulation of medial plantar nerve at the sole of foot.</p><p><strong>Materials and methods: </strong>Twenty adults with SCI having episode of at least 1 leak/day due to detrusor overactivity as diagnosed by cystometrogram (CMG), were on clean intermittent catheterization and ankle jerk was present consented for the study. Participants were asked to maintain bladder diary a week before and during 2 weeks of treatment. CMG was done on day-0 and day-14. cmcUroModul@tor<sup>®</sup>, an inhouse developed electrical stimulator was used for ½ h daily for period of 2 weeks. Patient satisfaction feedback questionnaire was taken on completion of treatment. CMG data were analyzed using Wilcoxon signed-ranked test while bladder diary was analyzed using binomial distribution. <i>P</i> < 0.05 was considered as statistically significant. Institutional Review Board (IRB) and ethics committee of Christian Medical College, Vellore, approved the study (CMC/IRB/11061).</p><p><strong>Results: </strong>Statistical significant improvement in maximum detrusor pressure (<i>P</i> = 0.03) and cystometric capacity (<i>P</i> = 0.04) was observed. Of 20 subjects, 18 showed improvement in bladder diary.</p><p><strong>Conclusion: </strong>Neuromodulation of medial plantar nerve at sole of foot by surface electrical stimulation is non-invasive, cost-effective, and alternative simple treatment modality for urinary incontinence due to detrusor overactivity.</p>","PeriodicalId":16443,"journal":{"name":"Journal of Neurosciences in Rural Practice","volume":"14 3","pages":"495-500"},"PeriodicalIF":1.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10570355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural magnetic resonance imaging in Parkinson disease with freezing of gait: A systematic review of literature. 帕金森病步态冻结的结构磁共振成像:文献系统综述。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-07-01 Epub Date: 2023-05-25 DOI: 10.25259/JNRP_107_2023
Ade Pambayu Suharto, Anggraini Dwi Sensusiati, Muhammad Hamdan, Dewi Setyaning Bastiana

Objective: This review aims to the existing structural neuroimaging literature in Parkinson disease presenting with freezing of gait. The summary of this article provides an opportunity for a better understanding of the structural findings of freezing of gait in Parkinson disease based on MRI.

Methods: This systematic review of literature follows the procedures as described by the guideline of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).

Results: Initial searches yielded 545 documents. After exclusions, 11 articles were included into our study. Current findings of structural MRI on freezing of gait in Parkinson disease are associated with structural damage between sensorimotor-related cortical grey matter structures and thalamus, but not cerebellum and smaller systems, as well as extensive injuries on white matter connecting between those structures.

Conclusion: Current findings of structural MRI on freezing of gait in Parkinson disease are associated with structural damage between sensorimotor-related cortical grey matter structures and thalamus, but not cerebellum and smaller systems, as well as extensive injuries on white matter connecting between those structures.

目的:对帕金森病步态冻结的结构神经影像学文献进行综述。本文的总结为更好地理解基于MRI的帕金森病步态冻结的结构发现提供了机会。方法:本文献的系统综述遵循系统综述和荟萃分析首选报告项目(PRISMA)指南所述的程序。结果:初步搜索产生545份文献。排除后,11篇文章被纳入我们的研究。帕金森病步态冻结的结构MRI当前发现与感觉运动相关的皮层灰质结构和丘脑之间的结构损伤有关,但与小脑和较小系统无关,以及这些结构之间连接的白质的广泛损伤有关。结论:目前帕金森病步态冻结的结构MRI结果与感觉运动相关的皮层灰质结构和丘脑之间的结构损伤有关,但与小脑和较小系统无关,以及这些结构之间连接的白质的广泛损伤有关。
{"title":"Structural magnetic resonance imaging in Parkinson disease with freezing of gait: A systematic review of literature.","authors":"Ade Pambayu Suharto,&nbsp;Anggraini Dwi Sensusiati,&nbsp;Muhammad Hamdan,&nbsp;Dewi Setyaning Bastiana","doi":"10.25259/JNRP_107_2023","DOIUrl":"10.25259/JNRP_107_2023","url":null,"abstract":"<p><strong>Objective: </strong>This review aims to the existing structural neuroimaging literature in Parkinson disease presenting with freezing of gait. The summary of this article provides an opportunity for a better understanding of the structural findings of freezing of gait in Parkinson disease based on MRI.</p><p><strong>Methods: </strong>This systematic review of literature follows the procedures as described by the guideline of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).</p><p><strong>Results: </strong>Initial searches yielded 545 documents. After exclusions, 11 articles were included into our study. Current findings of structural MRI on freezing of gait in Parkinson disease are associated with structural damage between sensorimotor-related cortical grey matter structures and thalamus, but not cerebellum and smaller systems, as well as extensive injuries on white matter connecting between those structures.</p><p><strong>Conclusion: </strong>Current findings of structural MRI on freezing of gait in Parkinson disease are associated with structural damage between sensorimotor-related cortical grey matter structures and thalamus, but not cerebellum and smaller systems, as well as extensive injuries on white matter connecting between those structures.</p>","PeriodicalId":16443,"journal":{"name":"Journal of Neurosciences in Rural Practice","volume":"14 3","pages":"399-405"},"PeriodicalIF":1.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483193/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10220972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychological distress and quality of community life among migratory construction workers in India. 印度移民建筑工人的心理困扰和社区生活质量。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-07-01 Epub Date: 2023-01-13 DOI: 10.25259/JNRP_42_2022
Sudhir Babu Sriramalu, Aravind Raj Elangovan, Sadananda Reddy Annapally, Raju Birudu, Govindappa Lakshmana

Objectives: The objectives of this study are to elicit sociodemographic details, assess the level of psychological distress, and measure the quality of community life (QoCL) of migratory construction workers.

Materials and methods: A cross-sectional research design and survey method of sampling was followed. The semi-structured interview schedule, self-reporting questionnaire, and QoCL scale were used as measures for the study.

Results: Out of 75 respondents, 37 (49.3%) did not have formal education, 38 (50.7%) have migrated for less than a month duration, 33 (44.0%) respondents migrated with their families. The mean age of respondents was 32.03 ± 9.82 years. About 48 (64.0%) were identified as potential respondents for psychosocial care and female respondents (M = 12.90 ± 4.03, t = -3.03, P < 0.003) have higher distress than males (M = 9.50 ± 4.56, t = -3.03, P < 0.003) ones. Overall, QoCL indicated a below moderate (59.08 ± 8.31) level.

Conclusion: The distress was high and QoCL indicated a below moderate level. Intersectoral and community mental health services were required to enhance QoCL and reduce distress among migratory construction workers.

目的:本研究的目的是了解移民建筑工人的社会人口统计细节,评估他们的心理困扰程度,并衡量他们的社区生活质量。材料和方法:采用横断面研究设计和抽样调查方法。采用半结构化访谈表、自我报告问卷和生活质量量表作为研究指标。结果:在75名受访者中,37人(49.3%)没有受过正规教育,38人(50.7%)移民时间不到一个月,33人(44.0%)与家人一起移民。受访者的平均年龄为32.03±9.82岁。约有48人(64.0%)被确定为心理社会护理的潜在受访者,女性受访者(M=12.90±4.03,t=-3.03,P<0.003)的痛苦程度高于男性受访者(M=9.50±4.56,t=-3.02,P<.003)。总体而言,生活质量生活水平低于中等水平(59.08±8.31)。结论:患者痛苦程度较高,生活质量水平为中度以下。需要跨部门和社区的心理健康服务来提高生活质量,减少移民建筑工人的痛苦。
{"title":"Psychological distress and quality of community life among migratory construction workers in India.","authors":"Sudhir Babu Sriramalu,&nbsp;Aravind Raj Elangovan,&nbsp;Sadananda Reddy Annapally,&nbsp;Raju Birudu,&nbsp;Govindappa Lakshmana","doi":"10.25259/JNRP_42_2022","DOIUrl":"10.25259/JNRP_42_2022","url":null,"abstract":"<p><strong>Objectives: </strong>The objectives of this study are to elicit sociodemographic details, assess the level of psychological distress, and measure the quality of community life (QoCL) of migratory construction workers.</p><p><strong>Materials and methods: </strong>A cross-sectional research design and survey method of sampling was followed. The semi-structured interview schedule, self-reporting questionnaire, and QoCL scale were used as measures for the study.</p><p><strong>Results: </strong>Out of 75 respondents, 37 (49.3%) did not have formal education, 38 (50.7%) have migrated for less than a month duration, 33 (44.0%) respondents migrated with their families. The mean age of respondents was 32.03 ± 9.82 years. About 48 (64.0%) were identified as potential respondents for psychosocial care and female respondents (M = 12.90 ± 4.03, <i>t</i> = -3.03, <i>P</i> < 0.003) have higher distress than males (M = 9.50 ± 4.56, <i>t</i> = -3.03, <i>P</i> < 0.003) ones. Overall, QoCL indicated a below moderate (59.08 ± 8.31) level.</p><p><strong>Conclusion: </strong>The distress was high and QoCL indicated a below moderate level. Intersectoral and community mental health services were required to enhance QoCL and reduce distress among migratory construction workers.</p>","PeriodicalId":16443,"journal":{"name":"Journal of Neurosciences in Rural Practice","volume":"14 3","pages":"533-540"},"PeriodicalIF":1.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10219156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positioning accuracy and facet joints violation after percutaneous pedicle screws placement with robot-assisted versus fluoroscopy-guided technique: Systematic review and meta-analysis. 机器人辅助与荧光镜引导经皮椎弓根螺钉置入术后的定位准确性和小关节侵犯:系统综述和荟萃分析。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-07-01 Epub Date: 2023-07-27 DOI: 10.25259/JNRP_147_2023
Andrea Perna, Calogero Velluto, Amarildo Smakaj, Francesco Tamburrelli, Maria Ilaria Borruto, Domenico Alessandro Santagada, Franco Lucio Gorgoglione, Francesco Liuzza, Luca Proietti

Introduction: Minimally invasive spine surgery became the gold standard for the treatment of many spinal diseases. Only a few comparative studies were performed regarding the superiority of robotic-assisted (RA) surgery over fluoroscopic guidance (FG) surgery during percutaneous pedicle screws placement. Therefore, the aim of the present study was to conduct a systematic literature review and meta-analysis to evaluate the accuracy and potential advantages of RA compared with FG.

Material and methods: This study is a systematic literature review conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. The review questions were formulated following the PICO scheme. Measured outcomes were presented using Forest plots. Heterogeneity among the included studies was assessed using the χ2 test, and the I2 statistic was utilized to estimate the proportion of total variation among the studies. A value exceeding 50% was considered indicative of substantial heterogeneity.

Results: Seven studies that met inclusion criteria were finally included in this meta-analysis. These seven studies include: 447 patients, 228 patients (931 screws) treated with robotic guide, and 219 patients (767 pedicle screws) using fluoroscopic guide, with a mean age of 55.2. The percentages of clinically acceptable screws were 94.3% in the robot-assisted group and 89% in the fluoroscopic guided group. The percentages of non-acceptable screws were 5.7% in the robot-assisted group and 11% in the fluoroscopic-guided group.

Discussion: Significant differences were observed between the two groups in terms of radiographic and clinical outcomes, with the robotic-assisted pedicle screw group exhibiting longer operative times. Robot technology serves as a valuable tool for assisting surgeons in challenging scenarios such as anatomical variants or patients with spinal deformities, ensuring accurate screw placement.

Conclusion: The accuracy of pedicle screw placement with robotic technology is higher than with FG. In fact, the robotic approach allows significantly lower complication rates, fewer cases of violation of the proximal articular facet, less intraoperative exposure to radiation, even if it requires longer surgical times than the FG technique.

简介:微创脊柱手术成为治疗许多脊柱疾病的黄金标准。关于经皮椎弓根螺钉置入过程中机器人辅助(RA)手术优于荧光镜引导(FG)手术的优越性,仅进行了少数比较研究。因此,本研究的目的是进行系统的文献综述和荟萃分析,以评估RA与FG相比的准确性和潜在优势。材料和方法:本研究是根据系统综述首选报告项目和荟萃分析指南进行的系统文献综述。审查问题是根据PICO方案制定的。测量结果采用森林图表示。使用χ2检验评估纳入研究之间的异质性,并使用I2统计量估计研究之间的总变异比例。超过50%的数值被认为表明存在显著的异质性。结果:符合纳入标准的7项研究最终纳入本荟萃分析。这七项研究包括:447名患者,228名患者(931颗螺钉)接受机器人引导治疗,219名患者(767颗椎弓根螺钉)接受荧光镜引导治疗,平均年龄55.2岁。机器人辅助组和荧光镜引导组的临床可接受螺钉百分比分别为94.3%和89%。不合格螺钉的百分比在机器人辅助组为5.7%,在荧光镜引导组为11%。讨论:两组在放射学和临床结果方面存在显著差异,机器人辅助椎弓根螺钉组的手术时间更长。机器人技术是一种有价值的工具,可以在解剖变异或脊柱畸形患者等具有挑战性的情况下帮助外科医生,确保螺钉的准确放置。结论:机器人技术放置椎弓根螺钉的准确性高于FG。事实上,机器人入路可以显著降低并发症发生率,减少近端关节面侵犯的病例,减少术中暴露于辐射的情况,即使它比FG技术需要更长的手术时间。
{"title":"Positioning accuracy and facet joints violation after percutaneous pedicle screws placement with robot-assisted versus fluoroscopy-guided technique: Systematic review and meta-analysis.","authors":"Andrea Perna,&nbsp;Calogero Velluto,&nbsp;Amarildo Smakaj,&nbsp;Francesco Tamburrelli,&nbsp;Maria Ilaria Borruto,&nbsp;Domenico Alessandro Santagada,&nbsp;Franco Lucio Gorgoglione,&nbsp;Francesco Liuzza,&nbsp;Luca Proietti","doi":"10.25259/JNRP_147_2023","DOIUrl":"10.25259/JNRP_147_2023","url":null,"abstract":"<p><strong>Introduction: </strong>Minimally invasive spine surgery became the gold standard for the treatment of many spinal diseases. Only a few comparative studies were performed regarding the superiority of robotic-assisted (RA) surgery over fluoroscopic guidance (FG) surgery during percutaneous pedicle screws placement. Therefore, the aim of the present study was to conduct a systematic literature review and meta-analysis to evaluate the accuracy and potential advantages of RA compared with FG.</p><p><strong>Material and methods: </strong>This study is a systematic literature review conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. The review questions were formulated following the PICO scheme. Measured outcomes were presented using Forest plots. Heterogeneity among the included studies was assessed using the χ<sup>2</sup> test, and the I<sup>2</sup> statistic was utilized to estimate the proportion of total variation among the studies. A value exceeding 50% was considered indicative of substantial heterogeneity.</p><p><strong>Results: </strong>Seven studies that met inclusion criteria were finally included in this meta-analysis. These seven studies include: 447 patients, 228 patients (931 screws) treated with robotic guide, and 219 patients (767 pedicle screws) using fluoroscopic guide, with a mean age of 55.2. The percentages of clinically acceptable screws were 94.3% in the robot-assisted group and 89% in the fluoroscopic guided group. The percentages of non-acceptable screws were 5.7% in the robot-assisted group and 11% in the fluoroscopic-guided group.</p><p><strong>Discussion: </strong>Significant differences were observed between the two groups in terms of radiographic and clinical outcomes, with the robotic-assisted pedicle screw group exhibiting longer operative times. Robot technology serves as a valuable tool for assisting surgeons in challenging scenarios such as anatomical variants or patients with spinal deformities, ensuring accurate screw placement.</p><p><strong>Conclusion: </strong>The accuracy of pedicle screw placement with robotic technology is higher than with FG. In fact, the robotic approach allows significantly lower complication rates, fewer cases of violation of the proximal articular facet, less intraoperative exposure to radiation, even if it requires longer surgical times than the FG technique.</p>","PeriodicalId":16443,"journal":{"name":"Journal of Neurosciences in Rural Practice","volume":"14 3","pages":"406-412"},"PeriodicalIF":1.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10220964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential modifications on verbal-language/orientation-memory ratio from Addenbrooke's cognitive examination III to predict mild cognitive impairment from healthy controls. Addenbrooke认知检查III对言语语言/定向记忆比率的潜在修改,以预测健康对照组的轻度认知障碍。
IF 1.4 Q4 CLINICAL NEUROLOGY Pub Date : 2023-07-01 Epub Date: 2023-08-16 DOI: 10.25259/JNRP_223_2023
R Meghana, Shubham Jain, Palash Kumar Malo, Albert Stezin, Thomas Gregor Issac
{"title":"Potential modifications on verbal-language/orientation-memory ratio from Addenbrooke's cognitive examination III to predict mild cognitive impairment from healthy controls.","authors":"R Meghana,&nbsp;Shubham Jain,&nbsp;Palash Kumar Malo,&nbsp;Albert Stezin,&nbsp;Thomas Gregor Issac","doi":"10.25259/JNRP_223_2023","DOIUrl":"10.25259/JNRP_223_2023","url":null,"abstract":"","PeriodicalId":16443,"journal":{"name":"Journal of Neurosciences in Rural Practice","volume":"14 3","pages":"531-532"},"PeriodicalIF":1.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10220975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Neurosciences in Rural Practice
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1