Journal of Nuclear Cardiology最新文献

{"title":"Heart rate response to regadenoson stress with positron emission tomography myocardial perfusion imaging: Old marker, new insights","authors":"Rami Doukky MD, MSc, MBA, FASNC","doi":"10.1016/j.nuclcard.2025.102557","DOIUrl":"10.1016/j.nuclcard.2025.102557","url":null,"abstract":"","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"54 ","pages":"Article 102557"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145470974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenging the Perugini grades: A case of 3-hour 99mTc HMDP washout","authors":"Brett W. Sperry MD, Erika Hutt MD","doi":"10.1016/j.nuclcard.2025.102295","DOIUrl":"10.1016/j.nuclcard.2025.102295","url":null,"abstract":"","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"54 ","pages":"Article 102295"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The changes in myocardial perfusion imaging landscape. A look at the human factor","authors":"Roberto Sciagrà MD","doi":"10.1016/j.nuclcard.2025.102558","DOIUrl":"10.1016/j.nuclcard.2025.102558","url":null,"abstract":"","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"54 ","pages":"Article 102558"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145471003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"National trends in radiopharmaceutical use for the diagnosis of cardiac amyloidosis from 2019 to 2024","authors":"Mirza S. Khan MD, MS , Hima Sanjana Perumalla MD , Karnav Modi MD , Talal Asif MD , Randall C. Thompson MD , Timothy M. Bateman MD , Brett W. Sperry MD","doi":"10.1016/j.nuclcard.2025.102502","DOIUrl":"10.1016/j.nuclcard.2025.102502","url":null,"abstract":"","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"54 ","pages":"Article 102502"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145185640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac nuclear imaging workforce: Trends from Medicare Part B (2013–2022)","authors":"Maria Alwan MD ,&nbsp;Ahmad El Yaman MD ,&nbsp;Ahmed Sayed MD ,&nbsp;Asim Shaikh MD ,&nbsp;Phillips M. Lawrence MD ,&nbsp;Mahmoud Al Rifai MD, MPH ,&nbsp;Mouaz H. Al-Mallah MD, MSc","doi":"10.1016/j.nuclcard.2025.102472","DOIUrl":"10.1016/j.nuclcard.2025.102472","url":null,"abstract":"<div><h3>Background</h3><div>Cardiac positron emission tomography (PET) and single-photon emission computed tomography (SPECT) are widely used for the assessment of coronary artery disease. While SPECT remains more available, workforce shortages and training demands contribute to geographic disparities in PET availability, impacting patient access to advanced imaging. Therefore, we assessed trends in the U.S. cardiac nuclear imaging workforce.</div></div><div><h3>Methods</h3><div>Data from Medicare Part B (2013-2022), provided by the Centers for Medicare &amp; Medicaid Services, were analyzed to assess trends in cardiac nuclear imaging services billed by physicians. The analysis focused on the number of readers, their gender, specialty, geographic distribution, and workload.</div></div><div><h3>Results</h3><div>From 2013 to 2022, the proportion of SPECT procedures declined from 95.8% (2,303,194 scans; 4393 per 100,000 Medicare beneficiaries) to 86.3% (1,386,358 scans; 2130 per 100,000 Medicare beneficiaries) of total nuclear cardiology procedures, while the proportion of PET procedures increased from 4.2% (99,861 scans; 190 per 100,000 Medicare beneficiaries) to 13.7% (220,366 scans; 339 per 100,000 Medicare beneficiaries). The majority of studies were interpreted by readers performing 50 or more studies annually. From 2013 to 2022, the number of SPECT-only readers declined from 17,013 to 13,491, while PET-only readers increased from 66 to 386. Readers interpreting both SPECT and PET doubled from 822 to 1643. Only 1 in 10 nuclear imaging readers were women and the majority were cardiologists. The median (interquartile range) number of studies per reader was higher for cardiologists compared to those of other specialties. Geographic disparities were evident, with most nuclear imaging readers practicing in Texas, Florida, and California, while the fewest were in Wyoming, Alaska, Vermont, and Washington, D.C.</div></div><div><h3>Conclusions</h3><div>While SPECT remained the most commonly used modality in 2022, its use has declined, whereas PET use has increased, accompanied by similar trends in the number of readers. Gender and geographic disparities persist in the distribution of nuclear cardiology imaging specialists. Addressing these gaps is essential to ensuring equitable access to nuclear imaging expertise.</div></div>","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"54 ","pages":"Article 102472"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Confirming expectations: Coronary artery calcification assessment provides diagnostic value in F18-flurpiridaz positron emission tomography myocardial perfusion imaging","authors":"Attila Feher MD, PhD ,&nbsp;Albert J. Sinusas MD","doi":"10.1016/j.nuclcard.2025.102559","DOIUrl":"10.1016/j.nuclcard.2025.102559","url":null,"abstract":"","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"54 ","pages":"Article 102559"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145458547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Our adventure: A year of innovation, collaboration, and global growth","authors":"Panithaya Chareonthaitawee MD, MASNC","doi":"10.1016/j.nuclcard.2025.102569","DOIUrl":"10.1016/j.nuclcard.2025.102569","url":null,"abstract":"","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"54 ","pages":"Article 102569"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145786714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incremental diagnostic value of artificial intelligence-derived coronary artery calcium in 18F-flurpiridaz positron emission tomography myocardial perfusion imaging","authors":"Orit Barrett MD, PhD ,&nbsp;Aakash Shanbhag MSc ,&nbsp;Ryan Zaid BSc ,&nbsp;Robert J.H. Miller MD ,&nbsp;Mark Lemley BSc ,&nbsp;Valerie Builoff BSc ,&nbsp;Joanna X. Liang MPH ,&nbsp;Paul B. Kavanagh MSc ,&nbsp;Christopher Buckley PhD ,&nbsp;Damini Dey PhD ,&nbsp;Daniel S. Berman MD ,&nbsp;Piotr J. Slomka PhD","doi":"10.1016/j.nuclcard.2025.102532","DOIUrl":"10.1016/j.nuclcard.2025.102532","url":null,"abstract":"<div><h3>Background</h3><div>Positron emission tomography (PET) myocardial perfusion imaging (MPI) is a powerful tool for predicting coronary artery disease (CAD). Coronary artery calcium (CAC) provides incremental risk stratification to PET-MPI and enhances diagnostic accuracy. We assessed the additive value of the CAC score, derived from PET/CT attenuation maps to stress total perfusion deficit (TPD) results using the novel ¹⁸F-flurpiridaz tracer in detecting significant CAD.</div></div><div><h3>Methods</h3><div>Patients from the ¹⁸F-flurpiridaz phase III clinical trial who underwent PET/CT MPI with the ¹⁸F-flurpiridaz tracer, had available computed tomography attenuation correction (CTAC) scans for CAC scoring, and underwent invasive coronary angiography (ICA) within a 6-month period between 2011 and 2013 were included. TPD was quantified automatically, and CAC scores from CTAC scans were assessed using artificial intelligence (AI)–derived segmentation and manual scoring. Obstructive CAD was defined as ≥50% stenosis in the left main (LM) artery, or 70% or more stenosis in any of the other major epicardial vessels. Prediction performance for CAD was assessed by comparing the area under receiver operating characteristic curve (AUC) for stress TPD alone and in combination with the CAC score.</div></div><div><h3>Results</h3><div>Among 498 patients (72% males, median age 63 years) 30.1% had CAD. Incorporating the CAC score resulted in a greater AUC with manual scoring (AUC = .87, 95% confidence interval [CI]: .34-.90; <em>P</em> = .015) and AI-based scoring (AUC = .88, 95% CI: .85-.90; <em>P</em> = .002) compared to stress TPD alone (AUC = .84, 95% CI: .80-.92).</div></div><div><h3>Conclusions</h3><div>Combining automatically derived TPD and CAC score enhances ¹⁸F-flurpiridaz PET MPI accuracy in detecting significant CAD, offering a method that can be routinely used with PET/CT scanners without additional scanning or technologist time.</div></div>","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"54 ","pages":"Article 102532"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145308330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative analysis of cadmium-zinc-telluride single-photon emission computed tomography/computed tomography to conventional single-photon emission computed tomography and positron emission tomography: Implications for risk stratification.","authors":"Ahmed Ibrahim Ahmed, Ibolya Csecs, Catherine Wright, Ioannis Kyriakoulis, Damianos G Kokkinidis, Edward J Miller, Attila Feher","doi":"10.1016/j.nuclcard.2025.102583","DOIUrl":"10.1016/j.nuclcard.2025.102583","url":null,"abstract":"","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":" ","pages":"102583"},"PeriodicalIF":2.7,"publicationDate":"2025-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145654495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic utility of longitudinal flow gradient for diagnosis of obstructive coronary artery disease in Rubidium-82 positron emission tomography.","authors":"Yoshito Kadoya, Kevin Boczar, Anahita Tavoosi, Gary R Small, Benjamin J W Chow, Rob Beanlands, Robert deKemp","doi":"10.1016/j.nuclcard.2025.102586","DOIUrl":"10.1016/j.nuclcard.2025.102586","url":null,"abstract":"<p><strong>Background: </strong>The longitudinal myocardial blood flow (MBF) gradient, reflecting the basal-to-apical decline in stress MBF, has been proposed as a non-invasive marker for obstructive coronary artery disease (CAD). However, its clinical utility in Rubidium-82 (⁸²Rb) positron emission tomography (PET) remains unestablished.</p><p><strong>Methods: </strong>This single-center retrospective study included consecutive patients who underwent rest/dipyridamole-stress ⁸²Rb PET myocardial perfusion imaging and invasive coronary angiography within 90 days from January 2012 to December 2019. Stress MBF and longitudinal gradients (basal-to-apical differences) were quantified in left anterior descending (LAD), left circumflex (LCX), and right coronary artery (RCA) territories. Coronary territories were stratified by coronary artery calcification (CAC) and perfusion defects (PD) into groups A (CAC-, PD-), B (CAC+, PD-), and C (PD+). Associations with CAD burden and diagnostic performance for obstructive CAD (≥50% angiographic stenosis) were evaluated using receiver operating characteristic analysis.</p><p><strong>Results: </strong>Of 1,516 patients screened, 396 (median age: 68 years; 30.6% female) were included, contributing 1,077 coronary territories (LAD: 391; LCX: 377; RCA: 309). In LAD territory, longitudinal MBF gradients increased with CAD burden (P < 0.001) and improved diagnostic accuracy beyond relative perfusion and stress MBF (AUC 0.774 vs 0.743, P = 0.002). Conversely, gradients in LCX and RCA territories decreased with increasing CAD burden (both P < 0.001) and did not improve diagnostic performance (LCX: AUC 0.704 vs 0.715, P = 0.267; RCA: AUC 0.727 vs 0.723, P = 0.698).</p><p><strong>Conclusions: </strong>Longitudinal stress MBF gradients derived from ⁸²Rb PET may enhance diagnostic accuracy for obstructive CAD in the LAD territory. No additional diagnostic value was observed in LCX or RCA territories.</p>","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":" ","pages":"102586"},"PeriodicalIF":2.7,"publicationDate":"2025-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145654553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}