Journal of Nuclear Cardiology最新文献

{"title":"How to differentiate obstructive from non-obstructive CAD with PET: Developments in high-resolution regional quantification of MBF and MFR","authors":"Jennifer M. Renaud , Mouaz H. Al-Mallah , Prem Soman , Robert A. deKemp , Rob S.B. Beanlands , Parthiban Arumugam , Ian S. Armstrong , John O. Prior , Chaitanya Madamanchi , Sascha N. Goonewardena , Alexis Poitrasson-Rivière , Jonathan B. Moody , Edward P. Ficaro , Venkatesh L. Murthy","doi":"10.1016/j.nuclcard.2024.102023","DOIUrl":"10.1016/j.nuclcard.2024.102023","url":null,"abstract":"","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"41 ","pages":"Article 102023"},"PeriodicalIF":3.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142046825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging quality in nuclear cardiology: The responsibility is with us all","authors":"Lawrence M. Phillips MD, MASNC","doi":"10.1016/j.nuclcard.2024.102054","DOIUrl":"10.1016/j.nuclcard.2024.102054","url":null,"abstract":"","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"41 ","pages":"Article 102054"},"PeriodicalIF":3.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CME INSTRUCTIONS: Cardiac positron emission tomography and other modalities for coronary artery disease assessment: A snapshot from the medicare data","authors":"","doi":"10.1016/j.nuclcard.2024.102076","DOIUrl":"10.1016/j.nuclcard.2024.102076","url":null,"abstract":"","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"41 ","pages":"Article 102076"},"PeriodicalIF":3.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of a single-item exercise questionnaire predicts prognostic risk among patients undergoing stress PET-MPI","authors":"Keiichiro Kuronuma ,&nbsp;Alan Rozanski ,&nbsp;Donghee Han ,&nbsp;Rebekah Park ,&nbsp;Guadalupe Flores Tomasino ,&nbsp;Sean W. Hayes ,&nbsp;Louise Thomson ,&nbsp;Damini Dey ,&nbsp;John D. Friedman ,&nbsp;Piotr J. Slomka ,&nbsp;Daniel S. Berman","doi":"10.1016/j.nuclcard.2024.102065","DOIUrl":"10.1016/j.nuclcard.2024.102065","url":null,"abstract":"<div><h3>Background</h3><div>Exercise activity reduces mortality and favorably influences mediators of risk, including myocardial flow reserve (MFR) and chronotropic responsiveness. Comprehensive research regarding the relationship between exercise activity, MFR, and chronotropic response to pharmacological stress, as assessed by heart rate response (HRR) among patients undergoing PET myocardial perfusion imaging (MPI) has not been performed. Thus, we aimed to evaluate the relationship between exercise activity as assessed by a practical single-item questionnaire, MFR and HRR, and longitudinal clinical risk.</div></div><div><h3>Methods</h3><div>We studied outpatients who underwent pharmacological stress rubidium-82. PET-MPI and answered a self-reported one-item exercise activity questionnaire (0–10 scale) at the time of PET-MPI. HRR was calculated by the following equation: (stress HR-rest HR)/rest HR∗100 (%). The primary outcome was death or myocardial infarction.</div></div><div><h3>Results</h3><div>Of 1686 patients, 221 (13%) patients had hard events during our mean follow up of 3.8 years. Patients were divided into four groups: no/minimal exercise (n = 551), low exercise (n = 468), moderate exercise (n = 485), and high exercise (n = 182) based on the questionnaire. MFR and HRR increased with exercise activity in a stepwise manner. By Cox analysis adjusted for clinical and PET-MPI variables including MFR and HRR, exercise activity was independently associated with hard events (HR [95%CI] per activity scale, .95 [.91-.99]; <em>P</em> = .028).</div></div><div><h3>Conclusions</h3><div>Patients with higher exercise activity assessed by a practical single-item questionnaire had higher MFR and HRR. Exercise activity was an independent predictor of hard events in patients undergoing PET-MPI. Because of its ease of use, this single-item questionnaire should be applied among patients undergoing stress MPI.</div></div>","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"41 ","pages":"Article 102065"},"PeriodicalIF":3.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical correlates of a single-item physical activity questionnaire among patients undergoing stress SPECT myocardial perfusion imaging","authors":"Alan Rozanski MD ,&nbsp;Heidi Gransar MS ,&nbsp;Robert J.H. Miller MD ,&nbsp;Donghee Han MD ,&nbsp;Sean Hayes MD ,&nbsp;John Friedman MD, MPH ,&nbsp;Louise Thomson MD ,&nbsp;Daniel Berman MD","doi":"10.1016/j.nuclcard.2024.102066","DOIUrl":"10.1016/j.nuclcard.2024.102066","url":null,"abstract":"<div><h3>Background</h3><div>There has been an increasing call for employing ultrashort exercise activity questionnaires as a clinical “vital sign”. To-date, this has not been applied to patients undergoing cardiac stress testing.</div></div><div><h3>Methods</h3><div>We evaluated 1136 patients who completed a one-item exercise questionnaire before undergoing stress SPECT myocardial perfusion imaging (MPI). This question asked patients to grade how much they exercise during daily life on a 11-point scale (0 = none, 10 = always). Patients were divided into four exercise activity groups based on their response: no, low, moderate, and high exercise activity. The results of this questionnaire were compared with patients’ clinical risk profile, mode of stress testing (exercise vs pharmacologic), and exercise treadmill duration.</div></div><div><h3>Results</h3><div>We noted a stepwise inverse relationship between exercise activity and patients’ frequency of hypertension, diabetes, and obesity (<em>P</em> &lt; .001 for each). Patients with no reported exercise activity were more likely to complain of dyspnea. There was a stepwise increase in the number of patients performing treadmill exercise with increasing reported exercise activity (<em>P</em> &lt; .001). The duration on treadmill exercise increased in stepwise fashion with higher patient reported exercise activity (<em>P</em> &lt; .001).</div></div><div><h3>Conclusion</h3><div>Our single-item, self-reported questionnaire was correlated with patients’ risk profiles, their mode of stress testing, and cardiorespiratory fitness. These correlates, along with the pragmatic nature of this ultrashort questionnaire, and its built-in identification of patients who may warrant exercise counseling, augurs for adopting ultrashort questionnaires regarding exercise activity among patients undergoing stress MPI, and other cardiac imaging tests where functional capacity is not routinely assessed.</div></div>","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"41 ","pages":"Article 102066"},"PeriodicalIF":3.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142564386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Slow or fast infusion profiles for Rubidium-82–What is the fuzz about?","authors":"Martin Lyngby Lassen PhD,&nbsp;Philip Hasbak MD, DMSc","doi":"10.1016/j.nuclcard.2024.102068","DOIUrl":"10.1016/j.nuclcard.2024.102068","url":null,"abstract":"","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"41 ","pages":"Article 102068"},"PeriodicalIF":3.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to differentiate obstructive from non-obstructive CAD with quantitative PET MPI using coronary flow capacity","authors":"Nils P. Johnson MD, MS,&nbsp;K. Lance Gould MD","doi":"10.1016/j.nuclcard.2024.102039","DOIUrl":"10.1016/j.nuclcard.2024.102039","url":null,"abstract":"","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"41 ","pages":"Article 102039"},"PeriodicalIF":3.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142267682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing vasodilator stress","authors":"Joseph C. Lee MBBS, FRACP, FAANMS ,&nbsp;Jia Wen Chong B Med Sci, MBBS, Grad Dip Clin Ed ,&nbsp;William W. Chik MBBS, FRACP, FCSANZ","doi":"10.1016/j.nuclcard.2024.102034","DOIUrl":"10.1016/j.nuclcard.2024.102034","url":null,"abstract":"","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"41 ","pages":"Article 102034"},"PeriodicalIF":3.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142073051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical risk stratification and myocardial perfusion imaging: Could a questionnaire give the answer?","authors":"Roberta Assante MD, PhD,&nbsp;Wanda Acampa MD, PhD","doi":"10.1016/j.nuclcard.2024.102069","DOIUrl":"10.1016/j.nuclcard.2024.102069","url":null,"abstract":"","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"41 ","pages":"Article 102069"},"PeriodicalIF":3.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac positron emission tomography and other modalities for coronary artery disease assessment: A snapshot from the medicare data","authors":"Mouaz Al-Mallah MD, MSc ,&nbsp;Maria Alwan MD ,&nbsp;Mahmoud Al Rifai MD, MPH ,&nbsp;Ahmed Sayed MBBS","doi":"10.1016/j.nuclcard.2024.102030","DOIUrl":"10.1016/j.nuclcard.2024.102030","url":null,"abstract":"<div><h3>Background</h3><div>Positron emission tomography (PET) is an important tool for assessing coronary artery disease (CAD), but its widespread utilization is limited due to various factors, including limited local champion availability. This study aims to compare the frequency of PET procedures and their interpreters with other common CAD assessment modalities.</div></div><div><h3>Methods</h3><div>Using Medicare data, we examined the number of cardiac PET procedures billed and compared them with single-photon emission computed tomography (SPECT), coronary computed tomography angiography (CCTA), stress magnetic resonance imaging (MRI), and stress echocardiography. Healthcare Common Procedure Coding System codes were used to identify procedures. We calculated the total number of PET myocardial perfusion imaging (MPI) procedures, the proportion of PET/CT and myocardial blood flow (MBF) assessments, and the median number of studies read per physician. We also analyzed the trends in the use of different CAD assessment modalities between 2018 and 2022. Descriptive statistics summarized the data.</div></div><div><h3>Results</h3><div>In 2022, Medicare billed for 212,106 PET MPI scans. SPECT was six times more frequent (1,343,519), whereas stress echocardiography (201,676) and CCTA (118,734) had similar or lower use. Stress MRI (3,932) was least used. Of the PET MPI scans, 46% were PET/CT, and 39% included MBF measurements. Cardiologists interpreted 86% of PET scans, with a median of 58 studies per reader; 23% interpreted ≤25 studies annually. SPECT had a median of 63 studies per reader, and CCTA, stress MRI, and stress echocardiography had medians of 27, 20, and 24, respectively. PET, CT, and MRI use increased from 2018 to 2022, whereas SPECT and stress echocardiography declined.</div></div><div><h3>Conclusion</h3><div>In the Medicare population, radionuclide perfusion imaging (SPECT and PET) remained the preferred method for assessment of CAD, with SPECT being the most frequently used modality and PET being the second most frequently used modality for this application. However, PET/CT and MBF are underutilized, limiting diagnostic and prognostic capabilities. Efforts to enhance education and awareness of PET's advantages and to address barriers to its wider adoption are essential to maximize its clinical benefits and improve patient outcomes.</div></div>","PeriodicalId":16476,"journal":{"name":"Journal of Nuclear Cardiology","volume":"41 ","pages":"Article 102030"},"PeriodicalIF":3.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142132959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}