Background: Preterm infants have a greater susceptibility to serious infections because their skin barrier has not fully functioned properly. Early birth in preterm infants causes immaturity of the barrier development, in the form of a thinner stratum corneum. Therefore extra care is needed to maintain the integrity of their skin to prevent infection, where the main recommendation is the administration of emollients, such as coconut oil. Virgin coconut oil contains nutrients and lauric acid that are more maintained and higher than coconut oil. Changes in skin integrity can cause extensive skin damage and become risk factors for infection. Erythema or damage to the skin such as erosion, excoriation, or crusting can be an early symptom of life-threatening infection in preterm infants. Assessment of skin integrity can be assessed objectively using the Neonatal Skin Condition Score (NSCS). Virgin coconut oil as an emollient with its antimicrobial activity is expected to allow improvement of the barrier structure of the skin. Aim: The purpose of this study is to review previous studies to provide a systematic summary of the effectiveness of topical coconut oil in improving the skin integrity of premature infants. Methods: Searching the electronic database Pubmed-MEDLINE, Scopus, ProQuest, Cochrane library, ClinicalTrials.gov, and Google Scholar, found five most relevant articles included in the qualitative and two of those five articles included in the meta-analysis. Result: The meta-analysis of the effect of topical VCO compared with control on NSCS values in preterm infants showed the value of heterogeneity test with Tau2=0.04 df=1; p=0.13, I2=55%. The value of the Q statistic was z value = 5.23 (p < 0.001). This shows that the overall administration of topical VCO can significantly improve the value of NSCS on preterm infants. The results of the overall meta-analysis showed that the overall standardized mean difference in NSCS between the intervention group compared to control was -0.93[-1.28 -0.58] (p < 0.001). These results indicate that the overall NSCS value of the intervention group was significantly better than the control group. Conclusion: Data from a systematic review and meta-analysis showed that the application of VCO can provide significantly better results in improving the skin integrity of preterm infants
{"title":"The Effectiveness of Virgin Coconut Oil Application on Improving the Skin Integrity of Preterm Infants; Systematic Review and Meta-analysis with Parameters Neonatal Skin Condition Score","authors":"Zidni S","doi":"10.23880/cdoaj-16000253","DOIUrl":"https://doi.org/10.23880/cdoaj-16000253","url":null,"abstract":"Background: Preterm infants have a greater susceptibility to serious infections because their skin barrier has not fully functioned properly. Early birth in preterm infants causes immaturity of the barrier development, in the form of a thinner stratum corneum. Therefore extra care is needed to maintain the integrity of their skin to prevent infection, where the main recommendation is the administration of emollients, such as coconut oil. Virgin coconut oil contains nutrients and lauric acid that are more maintained and higher than coconut oil. Changes in skin integrity can cause extensive skin damage and become risk factors for infection. Erythema or damage to the skin such as erosion, excoriation, or crusting can be an early symptom of life-threatening infection in preterm infants. Assessment of skin integrity can be assessed objectively using the Neonatal Skin Condition Score (NSCS). Virgin coconut oil as an emollient with its antimicrobial activity is expected to allow improvement of the barrier structure of the skin. Aim: The purpose of this study is to review previous studies to provide a systematic summary of the effectiveness of topical coconut oil in improving the skin integrity of premature infants. Methods: Searching the electronic database Pubmed-MEDLINE, Scopus, ProQuest, Cochrane library, ClinicalTrials.gov, and Google Scholar, found five most relevant articles included in the qualitative and two of those five articles included in the meta-analysis. Result: The meta-analysis of the effect of topical VCO compared with control on NSCS values in preterm infants showed the value of heterogeneity test with Tau2=0.04 df=1; p=0.13, I2=55%. The value of the Q statistic was z value = 5.23 (p < 0.001). This shows that the overall administration of topical VCO can significantly improve the value of NSCS on preterm infants. The results of the overall meta-analysis showed that the overall standardized mean difference in NSCS between the intervention group compared to control was -0.93[-1.28 -0.58] (p < 0.001). These results indicate that the overall NSCS value of the intervention group was significantly better than the control group. Conclusion: Data from a systematic review and meta-analysis showed that the application of VCO can provide significantly better results in improving the skin integrity of preterm infants","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"731 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123857190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The perception process allows us to experience the world around us, the use of communication techniques can improve the satisfaction of patients' relatives, reduce anxiety and stress, as well as effective communication between nurses and patients/ relatives it is one of the most important elements to improve hospital stay and treatment compliance. The objective was to determine the perception of the relatives of the surgical patient regarding the communication of the nursing staff, through the application of semi-structured interviews. A descriptive design with a qualitative approach was used, framed in the phenomenological paradigm, a semi-structured interview was applied, with a duration of approximately 15 to 20 minutes, with an intentional convenience sampling, which justifies the selection of 20 relatives. of surgical patients recruited on the outskirts of a public hospital, where information saturation was reached. For the analysis of the data, a graph was prepared to represent the responses of the participants according to the categories previously established by the authors. It is concluded that in all the categories the informants, that is, the relatives of the surgical patients, expressed negative responses towards the effective communication of the nursing staff, which makes us aware that the health personnel must be more empathetic and social with users and the family environment, in order to meet the objective of providing quality care and warmth
{"title":"Perception of the Family Members of the Surgical Patient Regarding the Communication of the Nursing Staff","authors":"Herrera Lopez Jose Luis","doi":"10.23880/cdoaj-16000293","DOIUrl":"https://doi.org/10.23880/cdoaj-16000293","url":null,"abstract":"The perception process allows us to experience the world around us, the use of communication techniques can improve the satisfaction of patients' relatives, reduce anxiety and stress, as well as effective communication between nurses and patients/ relatives it is one of the most important elements to improve hospital stay and treatment compliance. The objective was to determine the perception of the relatives of the surgical patient regarding the communication of the nursing staff, through the application of semi-structured interviews. A descriptive design with a qualitative approach was used, framed in the phenomenological paradigm, a semi-structured interview was applied, with a duration of approximately 15 to 20 minutes, with an intentional convenience sampling, which justifies the selection of 20 relatives. of surgical patients recruited on the outskirts of a public hospital, where information saturation was reached. For the analysis of the data, a graph was prepared to represent the responses of the participants according to the categories previously established by the authors. It is concluded that in all the categories the informants, that is, the relatives of the surgical patients, expressed negative responses towards the effective communication of the nursing staff, which makes us aware that the health personnel must be more empathetic and social with users and the family environment, in order to meet the objective of providing quality care and warmth","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122546009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pasteurella Dagmatis and Multocida Cellulitis Acquired from a Cat Bite : A Case Report","authors":"C. de Lorenzi","doi":"10.23880/cdoaj-16000256","DOIUrl":"https://doi.org/10.23880/cdoaj-16000256","url":null,"abstract":"","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125969557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pneumocystis jiroveci pneumonia (PCP) can be a fatal infection developing in those with and without HIV with an increased mortality in those without HIV. The development of biologics for autoimmune and dermatologic disease has increased the prevalence of patients who are immunocompromised due to medication. Our case presents a 51-year-old HIV negative male with psoriasis and psoriatic arthritis who developed PCP after initiating adalimumab. He had previously been taking methotrexate as monotherapy with inadequate control of symptoms. PCP can present with or without respiratory symptoms in those who are immunocompetent, which may cause unintentional shedding to those who are immunocompromised. Due to the detrimental effects of the infection, it is important for dermatologists to be aware of this potential risk of PCP with biologics and considerations for screening for PCP prior to initiating biologic therapy
{"title":"Pneumocystis Pneumonia after Initiation of Adalimumab in a Patient with Psoriasis and Concomitant Methotrexate-Induced Pancytopenia","authors":"Nicole D. Boswell","doi":"10.23880/cdoaj-16000309","DOIUrl":"https://doi.org/10.23880/cdoaj-16000309","url":null,"abstract":"Pneumocystis jiroveci pneumonia (PCP) can be a fatal infection developing in those with and without HIV with an increased mortality in those without HIV. The development of biologics for autoimmune and dermatologic disease has increased the prevalence of patients who are immunocompromised due to medication. Our case presents a 51-year-old HIV negative male with psoriasis and psoriatic arthritis who developed PCP after initiating adalimumab. He had previously been taking methotrexate as monotherapy with inadequate control of symptoms. PCP can present with or without respiratory symptoms in those who are immunocompetent, which may cause unintentional shedding to those who are immunocompromised. Due to the detrimental effects of the infection, it is important for dermatologists to be aware of this potential risk of PCP with biologics and considerations for screening for PCP prior to initiating biologic therapy","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127686461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of Ceramide Moisturizer in Atopic Dermatitis Systematic Review and Meta-analysis with Transepidermal Water Loss Parameters","authors":"S. Arifin","doi":"10.23880/cdoaj-16000266","DOIUrl":"https://doi.org/10.23880/cdoaj-16000266","url":null,"abstract":"","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127569837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy and Tolerability of a Novel Facial Serum","authors":"Simon Craw","doi":"10.23880/cdoaj-16000259","DOIUrl":"https://doi.org/10.23880/cdoaj-16000259","url":null,"abstract":"","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132145381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frostbite is a freezing, cold thermal injury, which occurs when tissues are exposed to temperatures below their freezing point for a sustained period of times. Frostbite is commonly found in countries with extreme cold climate and mostly found in military. Now a day’s frostbite is found in people associated with winter sports like skiing, hiking, ice climbing. In frostbite two distinct mechanisms, cellular death and necrosis are responsible for dermal ischemia. The extracellular ice crystals are initially formed due to freezing of tissues. These crystals disturb the osmotic gradient of the cell membrane and directly damaging the cell. Causing intracellular dehydration .The intracellular electrolyte concentration increases dramatically initiating cell death. Due to continuous fall in tissue temperature, there is formation of intracellular ice crystals and later theses ice crystals expand leading to mechanical detoration of cells. Anatomically hands and feet account for 90 % of reported injuries, and the others parts involved can be face, buttocks and penis. The role of thromboxane’s and prostaglandins has resulted in more active approach to the medical treatment of frostbite. However this study of leeching in frostbite showed outstanding results in the treatment of all forms of frostbite with very low
{"title":"Efficacy of Leeching in Frostbite","authors":"Iqbal A","doi":"10.23880/cdoaj-16000190","DOIUrl":"https://doi.org/10.23880/cdoaj-16000190","url":null,"abstract":"Frostbite is a freezing, cold thermal injury, which occurs when tissues are exposed to temperatures below their freezing point for a sustained period of times. Frostbite is commonly found in countries with extreme cold climate and mostly found in military. Now a day’s frostbite is found in people associated with winter sports like skiing, hiking, ice climbing. In frostbite two distinct mechanisms, cellular death and necrosis are responsible for dermal ischemia. The extracellular ice crystals are initially formed due to freezing of tissues. These crystals disturb the osmotic gradient of the cell membrane and directly damaging the cell. Causing intracellular dehydration .The intracellular electrolyte concentration increases dramatically initiating cell death. Due to continuous fall in tissue temperature, there is formation of intracellular ice crystals and later theses ice crystals expand leading to mechanical detoration of cells. Anatomically hands and feet account for 90 % of reported injuries, and the others parts involved can be face, buttocks and penis. The role of thromboxane’s and prostaglandins has resulted in more active approach to the medical treatment of frostbite. However this study of leeching in frostbite showed outstanding results in the treatment of all forms of frostbite with very low","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132901944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acne vulgaris is an inflammatory skin disorder of pilosebaceaous units. The clinical characteristics are seborrhea, sebaceous glands, non inflammatory lesions, inflammatory lesions and severe scaring. Propionibacterium acnes are the main pathophysiological factor influencing the acne development. Resistin gene is a novel proinflammatory cytokine involved in the initiation of inflammatory disorders like cardiovascular diseases, obesity and atherosclerosis. Various SNPs have been discovered in human RETN gene which is involved in different inflammatory disorders. Purpose of this study was to analyze RETN -420 C>G polymorphism in female acne patients of Pakistani population. About 58 control female subjects and 76 acne female patients were recruited for this study. In order to examine the RETN -420 C>G polymorphism in the promoter region, PCR and RFLP techniques were used. Statistically significant P value <0.05 for the RETN -420 C>G polymorphism was obtained in genotype/alleles frequencies between acne patients and control female subjects. Significant association between genotype frequencies, disease severity and acne scars distribution among female patients was also observed. It is concluded that RETN -420 promoter polymorphism was not associated with family history and skin types; however it was significantly associated with acne pathopysiology
{"title":"Resistin -420 C>G Polymorphism in Female Patients of Acne in Pakistan","authors":"Sufia Naz","doi":"10.23880/cdoaj-16000243","DOIUrl":"https://doi.org/10.23880/cdoaj-16000243","url":null,"abstract":"Acne vulgaris is an inflammatory skin disorder of pilosebaceaous units. The clinical characteristics are seborrhea, sebaceous glands, non inflammatory lesions, inflammatory lesions and severe scaring. Propionibacterium acnes are the main pathophysiological factor influencing the acne development. Resistin gene is a novel proinflammatory cytokine involved in the initiation of inflammatory disorders like cardiovascular diseases, obesity and atherosclerosis. Various SNPs have been discovered in human RETN gene which is involved in different inflammatory disorders. Purpose of this study was to analyze RETN -420 C>G polymorphism in female acne patients of Pakistani population. About 58 control female subjects and 76 acne female patients were recruited for this study. In order to examine the RETN -420 C>G polymorphism in the promoter region, PCR and RFLP techniques were used. Statistically significant P value <0.05 for the RETN -420 C>G polymorphism was obtained in genotype/alleles frequencies between acne patients and control female subjects. Significant association between genotype frequencies, disease severity and acne scars distribution among female patients was also observed. It is concluded that RETN -420 promoter polymorphism was not associated with family history and skin types; however it was significantly associated with acne pathopysiology","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128730870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Removing the Invisible Barrier to Medical Resources for Individuals with Leprous Histories: Report from a Communitybased Clinic in Japan","authors":"M. Namisato","doi":"10.23880/cdoaj-16000179","DOIUrl":"https://doi.org/10.23880/cdoaj-16000179","url":null,"abstract":"","PeriodicalId":164845,"journal":{"name":"Clinical Dermatology Open Access Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130104521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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