Pub Date : 2024-09-04DOI: 10.1097/WNO.0000000000002255
Elishai Assayag, Anastasia Semionov, Daniel Rappoport
{"title":"Monocular Blurred Vision and Ipsilateral Facial Numbness as Presenting Symptoms in a Child With Disseminated Burkitt Lymphoma.","authors":"Elishai Assayag, Anastasia Semionov, Daniel Rappoport","doi":"10.1097/WNO.0000000000002255","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002255","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142132966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-04DOI: 10.1097/WNO.0000000000002254
Caroline D Besley, Michael S Vaphiades, Lanning B Kline
{"title":"Formed Visual Hallucinations Precipitated by Eyelid Closure After Stroke.","authors":"Caroline D Besley, Michael S Vaphiades, Lanning B Kline","doi":"10.1097/WNO.0000000000002254","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002254","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-04DOI: 10.1097/WNO.0000000000002259
Marc A Bouffard, Mahsa Alborzi Avanaki, Jeremy N Ford, Narjes Jaafar, Alexander Brook, Bardia Abbasi, Nurhan Torun, David Alsop, Donnella S Comeau, Yu-Ming Chang
Background: The glymphatic system represents an extravascular network of astrocytic channels responsible for interstitial fluid and solute transit through the brain parenchyma. Its dysfunction has been considered as a possible cause of idiopathic intracranial hypertension (IIH).
Methods: We enrolled participants with active IIH, treated or cured IIH, and controls. The active IIH group was divided into untreated participants with recently developed (<6 mo) and chronic (6+ mo) disease. Glymphatic function was assessed using diffusion tensor imaging along the paravascular space (DTI-ALPS) to generate an ALPS-index, hypothesized to measure glymphatic function. Participants were imaged before lumbar puncture (LP) if IIH was suspected and following LP when possible.
Results: ALPS indices were higher in participants with chronically present, active IIH than in those either with recently developed IIH or control participants. ALPS-indices correlated with papilledema but did not correlate significantly with age, BMI, or intracranial pressure (ICP).
Conclusions: Our findings suggest that DTI-ALPS-indices of glymphatic function may be influenced by the chronicity of intracranial hypertension but do not support the hypothesis that glymphatic dysfunction causes IIH. Though these findings are preliminary, glymphatic imaging may be a useful radiographic biomarker in IIH.
{"title":"MRI Indices of Glymphatic Function Correlate With Disease Duration in Idiopathic Intracranial Hypertension.","authors":"Marc A Bouffard, Mahsa Alborzi Avanaki, Jeremy N Ford, Narjes Jaafar, Alexander Brook, Bardia Abbasi, Nurhan Torun, David Alsop, Donnella S Comeau, Yu-Ming Chang","doi":"10.1097/WNO.0000000000002259","DOIUrl":"10.1097/WNO.0000000000002259","url":null,"abstract":"<p><strong>Background: </strong>The glymphatic system represents an extravascular network of astrocytic channels responsible for interstitial fluid and solute transit through the brain parenchyma. Its dysfunction has been considered as a possible cause of idiopathic intracranial hypertension (IIH).</p><p><strong>Methods: </strong>We enrolled participants with active IIH, treated or cured IIH, and controls. The active IIH group was divided into untreated participants with recently developed (<6 mo) and chronic (6+ mo) disease. Glymphatic function was assessed using diffusion tensor imaging along the paravascular space (DTI-ALPS) to generate an ALPS-index, hypothesized to measure glymphatic function. Participants were imaged before lumbar puncture (LP) if IIH was suspected and following LP when possible.</p><p><strong>Results: </strong>ALPS indices were higher in participants with chronically present, active IIH than in those either with recently developed IIH or control participants. ALPS-indices correlated with papilledema but did not correlate significantly with age, BMI, or intracranial pressure (ICP).</p><p><strong>Conclusions: </strong>Our findings suggest that DTI-ALPS-indices of glymphatic function may be influenced by the chronicity of intracranial hypertension but do not support the hypothesis that glymphatic dysfunction causes IIH. Though these findings are preliminary, glymphatic imaging may be a useful radiographic biomarker in IIH.</p>","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-04DOI: 10.1097/WNO.0000000000002209
Yan-Ting Li, Qi-Ying Sun, Guang Yang
{"title":"Typical Clinical Phenotypes and Genotype in a Chinese Family With Congenital Fibrosis of the Extraocular Muscles Type 1.","authors":"Yan-Ting Li, Qi-Ying Sun, Guang Yang","doi":"10.1097/WNO.0000000000002209","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002209","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-04DOI: 10.1097/WNO.0000000000002251
James Ryan Loftus, Floyd A Warren, Thomas M Wisniewski, Timothy M Shepherd
{"title":"Positron Emission Tomography Fluorodeoxyglucose Correlates to Symptomatic Optic Tract Compression From Internal Carotid Artery Dolichoectasia That Progressed to Higher Cortical Visual Dysfunction.","authors":"James Ryan Loftus, Floyd A Warren, Thomas M Wisniewski, Timothy M Shepherd","doi":"10.1097/WNO.0000000000002251","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002251","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-04DOI: 10.1097/WNO.0000000000002246
April D Enger, Brian D Ellis, Grace A Levy-Clarke, Monique J Leys
{"title":"A Unique Case of Posterior Reversible Encephalopathy Syndrome Presenting With a Cranial Nerve 3 Palsy, a Bacillary Layer Retinal Detachment, and Bilateral Serous Retinal Detachments.","authors":"April D Enger, Brian D Ellis, Grace A Levy-Clarke, Monique J Leys","doi":"10.1097/WNO.0000000000002246","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002246","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-04DOI: 10.1097/WNO.0000000000002245
Heather M McDonald, Edward Margolin
{"title":"The Clue to Neurosarcoidosis Through Outer Retina: A Rare Case of Cavernous Sinus Sarcoidosis Uncovered Through Signs of Previous Posterior Uveitis.","authors":"Heather M McDonald, Edward Margolin","doi":"10.1097/WNO.0000000000002245","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002245","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-04DOI: 10.1097/WNO.0000000000002257
Eun Hye Oh, Yeon Jung Mun, Su-Jin Kim, Seo Young Choi, Kwang-Dong Choi, Jae-Hwan Choi
{"title":"A Variant of Latent Nystagmus in Congenital Cranial Dysinnervation Disorder.","authors":"Eun Hye Oh, Yeon Jung Mun, Su-Jin Kim, Seo Young Choi, Kwang-Dong Choi, Jae-Hwan Choi","doi":"10.1097/WNO.0000000000002257","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002257","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-04DOI: 10.1097/WNO.0000000000002256
Chloe Y Li, Todd L Rosenblat, Sameera Husain, David N Silvers, Alexander G Khandji, Meital Ben-Dov, Jeffrey G Odel, Sarah F Wesley
{"title":"Sweet Syndrome in the Central Nervous System: A Case of Orbital Inflammation, Sixth Nerve Palsy, and Pachymeningitis.","authors":"Chloe Y Li, Todd L Rosenblat, Sameera Husain, David N Silvers, Alexander G Khandji, Meital Ben-Dov, Jeffrey G Odel, Sarah F Wesley","doi":"10.1097/WNO.0000000000002256","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002256","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-04DOI: 10.1097/WNO.0000000000002253
Brigitte Simonsz-Toth, Konrad P Weber, Christina Gerth-Kahlert
{"title":"An Unusual Case of Voluntary Nystagmus Initiated by Head Shaking.","authors":"Brigitte Simonsz-Toth, Konrad P Weber, Christina Gerth-Kahlert","doi":"10.1097/WNO.0000000000002253","DOIUrl":"https://doi.org/10.1097/WNO.0000000000002253","url":null,"abstract":"","PeriodicalId":16485,"journal":{"name":"Journal of Neuro-Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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