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Journal of Obstetric Anaesthesia and Critical Care最新文献

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Neuraxial anaesthesia in a parturient with space occupying lesion in brain for caesarean section: Demystifying the myth – A case report with review 剖宫产术中脑占位性病变患者的轴向麻醉:揭穿神话-一例报告并复习
Pub Date : 2022-07-01 DOI: 10.4103/joacc.joacc_94_21
Abinaya Ramachandran, S. Segaran, Nikithamani, R. Ranjan
Pregnancy makes a patient undergo diverse physiological changes and predisposes them to many pathological disorders such as pre-eclampsia, eclampsia, cortical vein thrombosis, and pituitary apoplexy. Any intervention during pregnancy presents a unique challenge as it affects two individuals. Once diagnosed with a clinical condition, they are prone to further medical, obstetric and anaesthetic complications. Herein, we report the anaesthetic management of a 32-year-old female previously diagnosed with pituitary adenoma and now presenting with twin pregnancy for emergency caesarean section along with emphasis on the anaesthetic concerns pertinent to brain tumours in pregnancy.
妊娠使患者经历各种生理变化,并使他们容易患上许多病理性疾病,如先兆子痫、子痫、皮质静脉血栓形成和垂体卒中。怀孕期间的任何干预都是一个独特的挑战,因为它会影响两个人。一旦被诊断出患有临床疾病,他们很容易出现进一步的医疗、产科和麻醉并发症。在此,我们报告了一名32岁女性的麻醉处理,该女性先前被诊断为垂体腺瘤,现在出现双胎妊娠,需要紧急剖腹产,并强调了与妊娠期脑瘤相关的麻醉问题。
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引用次数: 0
A comparison between intrathecal nalbuphine versus fentanyl as an adjuvant with 0.5% hyperbaric bupivacaine for postoperative analgesia in parturients undergoing lower segment cesarean section 0.5%高压布比卡因与芬太尼辅助下段剖宫产术后镇痛的比较
Pub Date : 2022-07-01 DOI: 10.4103/joacc.joacc_67_21
Neena Jain, S. Sethi, Amrit Saini, Veena Patodi, Kavita Jain, Beena Thada
Background: Nalbuphine when used as an adjuvant to hyperbaric bupivacaine has improved the quality of perioperative analgesia. Fentanyl is a lipophilic opioid with a rapid onset and does not cause respiratory depression and improves duration of sensory anesthesia without producing significant side effects. The aim of this study was to compare intrathecal nalbuphine and fentanyl as adjuvants to hyperbaric bupivacaine for postoperative analgesia in lower segment cesarean section. Methods: A total of 100 American Society of Anesthesiologists (ASA) Physical Status (PS) I and II parturients were enrolled for lower segment cesarean section. Parturients were randomly allocated into 2 groups - Group F (n = 50) received bupivacaine 0.5% (heavy) 1.6 ml (8 mg) + fentanyl 20 μg (0.4 ml) and Group N (n = 50) received bupivacaine 0.5% (heavy) 1.6 ml (8 mg) + nalbuphine 0.4 mg (0.4 ml) under subarachnoid block (total volume = 2 ml). Time of onset and duration of sensory and motor block, Visual Analog Scale (VAS) score, duration of analgesia, sedation, rescue analgesic consumption, APGAR score, hemodynamic changes and adverse effects were noted. Results: Onset of sensory and motor block were significantly faster in Group F while duration of sensory block was significantly longer in Group N (P < 0.05). Duration of analgesia was also significantly longer in Group N (214.34 ± 9.31 min) compared to Group F (195.00 ± 9.18 min) (P < 0.001). No significant hemodynamic changes and adverse effects were noted in both groups (P > 0.05). Conclusion: Both of these drugs can be effectively used as an adjuvant to hyperbaric 0.5% bupivacaine in subarachnoid block for parturients undergoing lower segment cesarean section.
背景:纳洛酮作为高压布比卡因的辅助药物,可提高围手术期镇痛质量。芬太尼是一种亲脂性阿片类药物,起效快,不会引起呼吸抑制,可以延长感觉麻醉的持续时间,不会产生显著的副作用。本研究的目的是比较鞘内注射纳洛酮和芬太尼作为高压布比卡因辅助下段剖宫产术后镇痛的效果。方法:共有100名美国麻醉师协会(ASA)身体状况(PS)I和II产妇参加下段剖宫产。产妇被随机分为2组——F组(n=50)接受0.5%(重)1.6 ml(8 mg)的布比卡因+20μg(0.4 ml)的芬太尼,n组(n=5 0)在蛛网膜下腔阻滞(总体积=2 ml)下接受0.5%(轻)1.6 ml)的布比卡因+0.4 mg(0.4 ml。记录感觉和运动阻滞的发作时间和持续时间、视觉模拟量表(VAS)评分、镇痛持续时间、镇静、抢救性镇痛药消耗、APGAR评分、血液动力学变化和不良反应。结果:F组感觉阻滞和运动阻滞的发生速度明显加快,N组感觉阻滞持续时间明显延长(P<0.05),N组镇痛持续时间(214.34±9.31min)明显长于F组(195.00±9.18min)(P<0.001),两组均无明显的血液动力学变化和不良反应(P>0.05)。结论:这两种药物均可作为0.5%布比卡因高压蛛网膜下腔阻滞辅助下段剖宫产的有效药物。
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引用次数: 0
Medication errors in a parturient: A huge cost to two lives 产妇用药失误:两条生命的巨大代价
Pub Date : 2022-07-01 DOI: 10.4103/joacc.joacc_17_22
Manpreet Kaur, Bharat Yalla, A. Trikha
Medication errors in a parturient can be devastating as two lives are involved. Owing to the absence of critical incident reporting in parurients in multiple countries of the world, these errors are underreported. We herein discuss the common medication errors in a parturient, the published literature, and the management protocols practiced.
产妇的用药失误可能是毁灭性的,因为这涉及到两条生命。由于世界上多个国家的仓库中没有重大事件报告,这些错误报告不足。我们在此讨论产妇常见的药物错误、已发表的文献和实践的管理方案。
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引用次数: 0
Spinal anaesthesia, a special consideration in antiphospholipid antibody syndrome in pregnancy: A case series 脊髓麻醉是妊娠期抗磷脂抗体综合征的一个特殊考虑因素:一系列病例
Pub Date : 2022-01-01 DOI: 10.4103/joacc.joacc_74_21
Eesha Banerjee, S. Samanta, Soumya Samal
Antiphospholipid syndrome (APLA) is an acquired autoimmune disorder, clinically characterised by the development of thrombosis and obstetric morbidities comprising recurrent miscarriages, fetal deaths and premature births resulting from placental insufficiency such as intrauterine growth restriction and pre-eclampsia. It is the most common acquired hypercoagulable state where the focus of management is anticoagulation for the prevention of thrombosis.We report three cases of primary APLA syndrome in parturients at term with history of multiple abortions, being managed with oral aspirin and low molecular weight heparin posted for elective caesarian section. All three parturients were given single shot atraumatic spinal anaesthesia achieving a level of sensory blockade up to T6 since their coagulation profile showed no abnormalities. Antiphospholipid-antibody syndrome requires a multidisciplinary approach during pregnancy where use of anticoagulants may lead to dilemma of their perioperative continuation. Discontinuation of anticoagulants is a double-edged sword requiring careful deliberation on the part of anaesthetist to reduce the risk of perioperative bleeding.
抗磷脂综合征(APLA)是一种获得性自身免疫性疾病,临床特征为血栓形成和产科疾病,包括反复流产、胎儿死亡和胎盘功能不全导致的早产,如宫内生长受限和先兆子痫。它是最常见的获得性高凝状态,治疗的重点是抗凝以预防血栓形成。我们报告了三例有多次流产史的足月产妇的原发性APLA综合征,采用口服阿司匹林和低分子肝素进行选择性剖腹产治疗。所有三名产妇都接受了一次性无创伤脊髓麻醉,达到了T6的感觉阻断水平,因为她们的凝血特征没有显示异常。抗磷脂抗体综合征需要在妊娠期间采取多学科的方法,使用抗凝剂可能会导致围手术期继续使用的困境。抗凝血剂的停用是一把双刃剑,需要麻醉师仔细考虑,以降低围手术期出血的风险。
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引用次数: 0
Comparison of intravenous infusion versus bolus dose of oxytocin in elective caesarean delivery: A prospective, randomised study 择期剖宫产中静脉输注与口服催产素的比较:一项前瞻性随机研究
Pub Date : 2022-01-01 DOI: 10.4103/joacc.joacc_33_21
Jigisha Badheka, V. Oza, Nitin Manat, Mayur Patel
Background: Oxytocin (OT) is routinely administered during caesarean delivery to prevent and treat postpartum haemorrhage (PPH). The common adverse effects of intravenous OT are tachycardia, hypotension, chest pain, Electrocardiogram (ECG) changes, nausea and vomiting. We aimed to compare the uterine contractility, haemodynamic changes, need for other uterotonics and adverse effects by comparing the intravenous bolus dose versus infusion dose of OT while retaining its benefits. Methods: Sixty patients undergoing elective caesarean delivery under spinal anaesthesia were randomised to receive OT 3 IU as a bolus (repeat 3 IU at an interval of 3 min) in group B (Bolus) or as an infusion 1 IU per minute in group I (infusion). The uterine tone was assessed by a blinded obstetrician as either adequate or inadequate. The intraoperative heart rate, blood pressure, blood loss and any other adverse events were recorded. Results: The adequacy of uterine tone was more sustained and the requirement of other uterotonics was less in group I. The heart rate increased to 20–25 beats/min at 3–5 min in group B and 8–10 beats/min at 2–4 mins and reached the baseline at 8–9 min in group B as well as in group I. Also, a significant fall in the mean blood pressure was observed at 3–5 min in group B. The ECG changes (ST-T changes) were more common in group B compared to group I. There was no significant difference in the estimated blood loss between the two groups. Conclusion: The infusion dose of OT provides more haemodynamic stability, better uterine tone and fewer adverse effects compared to the bolus dose.
背景:催产素(OT)是剖腹产期间的常规用药,用于预防和治疗产后出血(PPH)。静脉OT常见的不良反应有心动过速、低血压、胸痛、心电图改变、恶心和呕吐。我们的目的是通过比较OT的静脉推注剂量和输注剂量来比较子宫收缩力、血液动力学变化、对其他子宫补剂的需求和不良反应,同时保留其益处。方法:60名在脊柱麻醉下接受选择性剖宫产的患者被随机分为B组(给药)接受OT 3IU的推注(每隔3分钟重复3IU),或I组(输注)接受每分钟1IU的输注。一位失明的产科医生评估子宫张力是否合适。记录术中心率、血压、失血和任何其他不良事件。结果:在I组中,子宫张力的充分性更持久,对其他子宫张力的需求更少。B组在3-5分钟时心率增加到20-25次/分,在2-4分钟时心率提高到8-10次/分。B组和I组在8-9分钟时达到基线。此外,B组在3-5min时观察到平均血压显著下降。与I组相比,B组的心电图变化(ST-T变化)更常见。两组的估计失血量没有显著差异。结论:与推注剂量相比,OT的输注剂量提供了更高的血液动力学稳定性、更好的子宫张力和更少的不良反应。
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引用次数: 0
Spontaneous postpartum intracranial haemorrhage: A case report 产后自发性颅内出血1例
Pub Date : 2022-01-01 DOI: 10.4103/joacc.joacc_81_21
M. Smith, James Walker, Sukruta Pradhan, F. Newton
Pregnancy-associated strokes are rare but can have detrimental effects on both mother and baby. A young female patient, 6 days postpartum, suffered a spontaneous intraparenchymal haemorrhage (IPH) and subarachnoid haemorrhage (SAH). The patient exhibited aphasia, right facial droop and right hemiparesis. Serial imaging showed no vascular malformation or other cause of her haemorrhages. Our pregnant patient presented with concurrent IPH and SAH. Given the timing of her stroke and the absence of underlying vascular lesion, it is possible her stroke was a case of IPH and SAH due to reversible cerebral vasoconstriction syndrome (RCVS). More specifically, it may reflect postpartum angiopathy, a subtype of RCVS presenting around 5 days postpartum. Alternatively, this could simply be a subarachnoid extension of a primary IPH.
妊娠相关中风很罕见,但可能对母亲和婴儿都有不利影响。一名年轻女性患者,产后6天,发生自发性脑实质内出血(IPH)和蛛网膜下腔出血(SAH)。患者表现为失语症、右侧面部下垂和右侧偏瘫。系列影像学检查显示,她的出血没有血管畸形或其他原因。我们的孕妇同时出现IPH和SAH。考虑到她的中风时间和没有潜在的血管病变,她的中风可能是由于可逆性脑血管收缩综合征(RCVS)引起的IPH和SAH。更具体地说,它可能反映产后血管病变,这是产后5天左右出现的RCVS的一种亚型。或者,这可能只是原发性IPH的蛛网膜下腔延伸。
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引用次数: 0
Pregnancy in thalassemia: Correspondence 地中海贫血怀孕:通信
Pub Date : 2022-01-01 DOI: 10.4103/joacc.joacc_106_21
P. Sookaromdee, V. Wiwanitkit
{"title":"Pregnancy in thalassemia: Correspondence","authors":"P. Sookaromdee, V. Wiwanitkit","doi":"10.4103/joacc.joacc_106_21","DOIUrl":"https://doi.org/10.4103/joacc.joacc_106_21","url":null,"abstract":"","PeriodicalId":16611,"journal":{"name":"Journal of Obstetric Anaesthesia and Critical Care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48935973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anaesthetic considerations for the parturient with myogenic differentiation-1 gene-related congenital myopathy and pre-eclampsia: A case report 肌源性差异-1基因相关先天性肌病和先兆子痫产妇的麻醉注意事项:一例报告
Pub Date : 2022-01-01 DOI: 10.4103/joacc.joacc_71_21
H. Misran, David W. Hoppe, Andrew Colls, Y. Ohashi
We present the anaesthetic management of a parturient with myogenic differentiation-1 gene-related congenital myopathy who presented for urgent caesarean section due to pre-eclampsia and respiratory failure. The challenges we faced include chronic respiratory failure with diaphragmatic dysfunction, difficulties with neuraxial anaesthesia, potential risk of triggering malignant hyperthermia in an unknown myopathy, and the complexities of multidisciplinary team involvement. As there is limited medical literature regarding this condition, we believe this is the first case report describing the anaesthetic care of a pregnant patient with this rare congenital myopathy.
我们介绍了一名患有肌源性分化-1基因相关先天性肌病的产妇的麻醉处理,该产妇因先兆子痫和呼吸衰竭而紧急剖腹产。我们面临的挑战包括慢性呼吸衰竭伴膈肌功能障碍、神经轴麻醉困难、未知肌病引发恶性热疗的潜在风险,以及多学科团队参与的复杂性。由于有关这种情况的医学文献有限,我们相信这是第一份描述这种罕见先天性肌病孕妇麻醉护理的病例报告。
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引用次数: 0
High flow nasal cannula (HFNC) and video laryngoscope (VL) as essential adjuncts in management of obstetric difficult airway: Efficacious tools or simply an industry push! 高流量鼻插管(HFNC)和视频喉镜(VL)作为产科困难气道管理的重要辅助工具:有效的工具或简单的行业推动!
Pub Date : 2022-01-01 DOI: 10.4103/joacc.joacc_108_21
A. Trikha, Manpreet Kaur
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引用次数: 1
Evaluation of 0.25% bupivacaine vs. 0.375% ropivacaine for postoperative analgesia using ultrasound guided transversus abdominis plane block for caesarean section: A comparative study 超声引导下剖宫产术中0.25%布比卡因与0.375%罗比卡因术后镇痛的比较研究
Pub Date : 2022-01-01 DOI: 10.4103/joacc.joacc_28_21
Damodar Puchakala, V. Joshi, Avanish Bhardwaj
Background: Pain after Caesarean section is described as moderate to severe by most patients. Ultrasound guided transversus abdominis plane (TAP) block is now increasingly being used for postoperative analgesia in lower abdominal surgeries. Hence this study was undertaken to compare 0.25% Bupivacaine with 0.375% Ropivacaine for postoperative analgesia using TAP block in caesarean section. Methods: Seventy patients were randomized into Group B (n = 35) and Group R (n = 35). TAP block was administered after completion of surgery under ultrasound guidance using 15 mL of 0.25% Bupivacaine in Group B and 15 mL of 0.375% Ropivacaine in Group R on each side of the abdomen. Time to requirement of first analgesic dosage was observed in both the groups. Total analgesic requirement in the first 24 h, visual analogue scale (VAS) scores at 2, 4, 6, 8, 12 and 24 h, patient satisfaction and complications were also noted. Results: Mean time for the first dose of rescue analgesia after completion of surgery was 298.2 ± 93.6 min in Group B and 447.6 ± 85.2 min in Group R (P = 0.0001). Total requirement of Diclofenac Sodium injection was 162.86 ± 46.88 mg in Group B whereas it was only 130.71 ± 44.49 mg in Group R (P = 0.003). VAS at 4,6 and 8 h after surgery were significantly lower in the Ropivacaine group. Conclusion: 0.375% Ropivacaine provided longer duration of analgesia and resulted in lesser analgesic requirement than 0.25% Bupivacaine when used in TAP block after caesarean section.
背景:剖腹产后的疼痛被大多数患者描述为中度至重度。超声引导的腹横肌平面阻滞(TAP)目前越来越多地用于下腹手术的术后镇痛。因此,本研究比较0.25%布比卡因和0.375%罗哌卡因在剖宫产术后TAP阻滞镇痛中的作用。方法:70例患者随机分为B组(n=35)和R组(n=5)。手术结束后,在超声引导下,在腹部两侧各使用15mL 0.25%布比卡因(B组)和15mL 0.375%罗哌卡因(R组)进行TAP阻滞。观察两组患者达到首次镇痛剂量所需的时间。还注意到前24小时的总镇痛需求、2、4、6、8、12和24小时的视觉模拟量表(VAS)评分、患者满意度和并发症。结果:术后第一次镇痛的平均时间B组为298.2±93.6min,R组为447.6±85.2min(P=0.0001)。双氯芬酸钠注射液的总需求量B组为162.86±46.88mg,而R组仅为130.71±44.49mg(P=0.003)。罗哌卡因组术后4、6和8h的VAS评分显著降低。结论:0.375%的罗哌卡因用于剖宫产术后TAP阻滞时,镇痛持续时间比0.25%的布比卡因更长,镇痛要求更低。
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引用次数: 0
期刊
Journal of Obstetric Anaesthesia and Critical Care
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