首页 > 最新文献

Journal of Occupational Health最新文献

英文 中文
Occupational radiation exposure of zoo veterinarians during x-ray procedures: a real-time dosimetry study. 动物园兽医在x光检查过程中的职业辐射暴露:实时剂量学研究。
IF 2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-06 DOI: 10.1093/joccuh/uiaf064
Keisuke Nagamoto, Aina Yamamoto, Noriko Takahashi, Ayako Nii, Masaoki Kohzaki, Ryuji Okazaki

Objectives: We used real-time dosimetry for the quantitative evaluation of occupational radiation exposure among zoo veterinarians and animal keepers during x-ray procedures to identify key procedural and contextual determinants of exposure variation.

Methods: This retrospective observational study analyzed 251 radiographic procedures at multiple zoological facilities in Japan. Occupational exposure was measured in real time with a semiconductor dosimeter that recorded the personal dose equivalent, Hp(10), at 1-second intervals. Procedural variables included professional role, manual restraint, sedation or anesthesia, equipment type, tube voltage (kVp), and tube current-time product (mAs). Between-group comparisons were conducted using nonparametric tests, and multiple linear regression was used to identify the independent predictors of occupational exposure.

Results: The overall median Hp(10) per procedure was 0.35 (IQR: 0.15-0.99) μSv. Veterinarians received significantly higher doses than animal keepers (P = .006). Elevated Hp(10) values were associated with procedures involving large-bodied carnivores, performed without manual restraint or sedation. Multivariate analysis identified 5 significant predictors-professional role (β = -.75), manual restraint (β = -.24), tube voltage (β = .43), tube current-time product (β = .11), and large-animal group (β = .34)-explaining 60.4% of the variance (adjusted R2 = 0.604).

Conclusions: Despite the overall low exposure levels, some procedures resulted in Hp(10) values exceeding 10 μSv. A combination of procedural and contextual factors influenced exposure. These findings underscore the importance of comprehensive radiation-protection strategies, including optimized workflows, appropriate use of sedation, and standardized operator protocols, in alignment with international dose-optimization principles.

目的:我们使用实时剂量法定量评估动物园兽医和动物饲养员在x射线检查过程中的职业辐射暴露,并确定暴露变化的关键程序和环境决定因素。方法:本回顾性观察研究分析了日本多家动物机构的251个x线摄影程序。用半导体剂量计实时测量职业性暴露,每隔一秒记录个人剂量当量Hp(10)。程序变量包括专业角色、人工约束、镇静或麻醉、设备类型、管电压(kVp)和管电流时间积(mAs)。使用非参数检验进行组间比较,并使用多元线性回归来确定职业暴露的独立预测因子。结果:每次手术的总中位Hp(10)为0.35 (IQR: 0.15-0.99) μSv。兽医接受的剂量明显高于动物饲养员(p = 0.006)。Hp(10)值升高与涉及大型食肉动物的手术有关,在没有人工约束或镇静的情况下进行。多变量分析确定了5个显著预测因子——专业作用(β = -0.75)、人工约束(β = -0.24)、管电压(β = 0.43)、管电流时间积(β = 0.11)和大型动物组(β = 0.34)——解释了60.4%的方差(调整后的R2 = 0.604)。结论:尽管总体暴露水平较低,但某些操作导致Hp(10)值超过10 μSv。程序和环境因素共同影响暴露。这些发现强调了综合辐射防护策略的重要性,包括优化工作流程、适当使用镇静和标准化操作规程,与国际剂量优化原则保持一致。
{"title":"Occupational radiation exposure of zoo veterinarians during x-ray procedures: a real-time dosimetry study.","authors":"Keisuke Nagamoto, Aina Yamamoto, Noriko Takahashi, Ayako Nii, Masaoki Kohzaki, Ryuji Okazaki","doi":"10.1093/joccuh/uiaf064","DOIUrl":"10.1093/joccuh/uiaf064","url":null,"abstract":"<p><strong>Objectives: </strong>We used real-time dosimetry for the quantitative evaluation of occupational radiation exposure among zoo veterinarians and animal keepers during x-ray procedures to identify key procedural and contextual determinants of exposure variation.</p><p><strong>Methods: </strong>This retrospective observational study analyzed 251 radiographic procedures at multiple zoological facilities in Japan. Occupational exposure was measured in real time with a semiconductor dosimeter that recorded the personal dose equivalent, Hp(10), at 1-second intervals. Procedural variables included professional role, manual restraint, sedation or anesthesia, equipment type, tube voltage (kVp), and tube current-time product (mAs). Between-group comparisons were conducted using nonparametric tests, and multiple linear regression was used to identify the independent predictors of occupational exposure.</p><p><strong>Results: </strong>The overall median Hp(10) per procedure was 0.35 (IQR: 0.15-0.99) μSv. Veterinarians received significantly higher doses than animal keepers (P = .006). Elevated Hp(10) values were associated with procedures involving large-bodied carnivores, performed without manual restraint or sedation. Multivariate analysis identified 5 significant predictors-professional role (β = -.75), manual restraint (β = -.24), tube voltage (β = .43), tube current-time product (β = .11), and large-animal group (β = .34)-explaining 60.4% of the variance (adjusted R2 = 0.604).</p><p><strong>Conclusions: </strong>Despite the overall low exposure levels, some procedures resulted in Hp(10) values exceeding 10 μSv. A combination of procedural and contextual factors influenced exposure. These findings underscore the importance of comprehensive radiation-protection strategies, including optimized workflows, appropriate use of sedation, and standardized operator protocols, in alignment with international dose-optimization principles.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12689550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145489056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occupational physicians' practices in supporting employees with long COVID: a mixed-methods study. 职业医生支持长冠员工的实践:一项混合方法研究。
IF 2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-06 DOI: 10.1093/joccuh/uiaf078
Yu Igarashi, Seiichiro Tateishi, Tomoko Sawajima, Arisa Harada, Juri Matsuoka, Mika Kawasumi, Koji Mori

Objectives: This study examined the support provided by occupational physicians (OPs) in Japan to employees with long COVID, a condition that significantly affected workforce health during the pandemic.

Methods: An exploratory cross-sectional mixed-methods design was employed, consisting of qualitative interviews followed by a questionnaire survey targeting OPs certified by the Japan Society for Occupational Health. The interviews explored actual experiences of supporting workers with long COVID, and the findings were used to develop the questionnaire. The survey and interview findings were integrated to describe overall occupational health (OH) practices.

Results: Twenty OPs reported 30 cases of employees with long COVID in the interviews. Based on these findings, a questionnaire survey was conducted, yielding 182 valid responses. The integrated results showed that OPs most frequently reported "Main OH responses" such as active listening, return-to-work assistance, and lifestyle guidance. Measures such as explaining workers' compensation applications and preparing lists of outpatient clinics were less frequently reported. For "Advice for employers," limitation of overtime, reduction of workload, and telework were commonly reported, whereas demotion and reassignment were rarely reported.

Conclusions: This study clarified how OPs in Japan supported workers with long COVID through diverse, context-dependent practices. The identified main OH responses and advice for employers provide a framework for understanding current practices. Developing practical case examples, structured assessment tools, and workplace guidelines, together with further research grounded in real-world practice, will enhance OPs' ability to provide appropriate support and strengthen preparedness for future health crises.

目的:本研究调查了日本职业医生(OPs)为长COVID员工提供的支持,这种情况在大流行期间严重影响了劳动力的健康。方法:采用探索性横截面混合方法设计,包括定性访谈和问卷调查,针对日本职业卫生协会认证的OPs。访谈探讨了支持长COVID员工的实际经验,并将调查结果用于编制问卷。将调查和访谈结果综合起来描述总体职业健康实践。结果:20个OPs在访谈中报告了30例长冠员工。基于这些发现,我们进行了问卷调查,得到182份有效回复。综合结果显示,OPs最常报告的主要OH响应,如积极倾听,重返工作协助和生活方式指导。解释工人赔偿申请和编制门诊诊所清单等措施的报告较少。在“雇主建议”中,限制加班、减少工作量和远程办公是常见的报告,而降职和重新分配的报告则很少。结论:本研究阐明了日本的OPs如何通过不同的、与环境相关的实践来支持患有长COVID的工人。确定的主要OH回应和对雇主的建议为理解当前的做法提供了一个框架。制定实际案例、结构化评估工具和工作场所准则,再加上基于现实实践的进一步研究,将提高项目厅提供适当支助的能力,并加强对未来健康危机的防范。
{"title":"Occupational physicians' practices in supporting employees with long COVID: a mixed-methods study.","authors":"Yu Igarashi, Seiichiro Tateishi, Tomoko Sawajima, Arisa Harada, Juri Matsuoka, Mika Kawasumi, Koji Mori","doi":"10.1093/joccuh/uiaf078","DOIUrl":"10.1093/joccuh/uiaf078","url":null,"abstract":"<p><strong>Objectives: </strong>This study examined the support provided by occupational physicians (OPs) in Japan to employees with long COVID, a condition that significantly affected workforce health during the pandemic.</p><p><strong>Methods: </strong>An exploratory cross-sectional mixed-methods design was employed, consisting of qualitative interviews followed by a questionnaire survey targeting OPs certified by the Japan Society for Occupational Health. The interviews explored actual experiences of supporting workers with long COVID, and the findings were used to develop the questionnaire. The survey and interview findings were integrated to describe overall occupational health (OH) practices.</p><p><strong>Results: </strong>Twenty OPs reported 30 cases of employees with long COVID in the interviews. Based on these findings, a questionnaire survey was conducted, yielding 182 valid responses. The integrated results showed that OPs most frequently reported \"Main OH responses\" such as active listening, return-to-work assistance, and lifestyle guidance. Measures such as explaining workers' compensation applications and preparing lists of outpatient clinics were less frequently reported. For \"Advice for employers,\" limitation of overtime, reduction of workload, and telework were commonly reported, whereas demotion and reassignment were rarely reported.</p><p><strong>Conclusions: </strong>This study clarified how OPs in Japan supported workers with long COVID through diverse, context-dependent practices. The identified main OH responses and advice for employers provide a framework for understanding current practices. Developing practical case examples, structured assessment tools, and workplace guidelines, together with further research grounded in real-world practice, will enhance OPs' ability to provide appropriate support and strengthen preparedness for future health crises.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12965807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145850272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occupational exposure to video display terminals: a systematic review of ocular and visual health effects and associated risk factors. 职业接触视频显示终端:眼部和视觉健康影响及相关危险因素的系统综述。
IF 2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-06 DOI: 10.1093/joccuh/uiaf073
Eva Artime-Ríos, Mar Seguí-Crespo, Begoña Doménech-Amigot, Mar Sánchez-Brau, Ana Suárez-Sánchez, José María Ramada-Rodilla

Objectives: To synthesize ocular and visual effects caused by occupational exposure to video display terminals (VDTs). Additionally, we aimed to identify the occupational and nonoccupational risk and protective factors related to these effects, and to propose a conceptual mapping to manage affected workers.

Methods: The review protocol was registered in PROSPERO and the systematic review was conducted following PRISMA guidelines. A search of MEDLINE, Scopus, and Web of Science was performed to identify studies published between January 2006 and December 2023. Only primary studies were included. Study quality was assessed using a critical appraisal tool based on STROBE statements for cross-sectional studies and the Scottish Intercollegiate Guideline Network checklist for randomized controlled trials and cohort and case-control studies. Low-quality studies were excluded.

Results: Eighty-five articles were included, 50 of high quality. The main ocular and visual effects were computer vision syndrome, dry eye disease, and other isolated signs and symptoms. The main risk factors were the daily hours of VDT exposure, female gender, use of ophthalmic or contact lenses, increasing age, altered lighting conditions, and job seniority. Breaks, adequate workstation design, and ergonomic improvements were the main protective factors. Psychosocial factors and lifestyle behaviors also may influence ocular and visual health at work.

Conclusions: Wide methodological variations were found, making it difficult to compare studies. Nevertheless, an evidence-informed conceptual mapping has been proposed that could be used as a starting point to guide preventive measures in VDT work settings. Further research with appropriate epidemiological designs is needed to establish causal relationships or determine temporal sequences between exposures and outcomes.

目的:综合研究职业性接触vdt对眼部和视觉的影响。此外,它旨在确定与这些影响有关的职业和非职业风险和保护因素,并提出一个概念图来管理受影响的工人。方法:审查方案在PROSPERO注册,并按照PRISMA指南进行系统审查。检索MEDLINE、Scopus和WOS以确定2006年1月至2023年12月间发表的研究。只纳入了初步研究。研究质量采用关键评估工具进行评估,该工具基于横断面研究的STROBE声明和随机对照试验、队列和病例对照研究的SIGN检查表。低质量的研究被排除在外。结果:纳入文献85篇,优质文献50篇。主要的眼部和视觉影响是计算机视觉综合征、干眼症和其他孤立的体征和症状。主要的危险因素是每日接触VDT的时间、女性、使用眼科眼镜或隐形眼镜、年龄增长、改变的照明条件和工作年长者。休息,适当的工作站设计和人体工程学的改进是主要的保护因素。心理社会因素和生活方式行为也可能影响工作时的眼睛和视力健康。结论:方法差异很大,使得比较研究变得困难。然而,已经提出了一种基于证据的概念图,可以作为指导VDT工作环境中预防措施的起点。需要有适当流行病学设计的进一步研究来确定暴露与结果之间的因果关系或确定时间序列。
{"title":"Occupational exposure to video display terminals: a systematic review of ocular and visual health effects and associated risk factors.","authors":"Eva Artime-Ríos, Mar Seguí-Crespo, Begoña Doménech-Amigot, Mar Sánchez-Brau, Ana Suárez-Sánchez, José María Ramada-Rodilla","doi":"10.1093/joccuh/uiaf073","DOIUrl":"10.1093/joccuh/uiaf073","url":null,"abstract":"<p><strong>Objectives: </strong>To synthesize ocular and visual effects caused by occupational exposure to video display terminals (VDTs). Additionally, we aimed to identify the occupational and nonoccupational risk and protective factors related to these effects, and to propose a conceptual mapping to manage affected workers.</p><p><strong>Methods: </strong>The review protocol was registered in PROSPERO and the systematic review was conducted following PRISMA guidelines. A search of MEDLINE, Scopus, and Web of Science was performed to identify studies published between January 2006 and December 2023. Only primary studies were included. Study quality was assessed using a critical appraisal tool based on STROBE statements for cross-sectional studies and the Scottish Intercollegiate Guideline Network checklist for randomized controlled trials and cohort and case-control studies. Low-quality studies were excluded.</p><p><strong>Results: </strong>Eighty-five articles were included, 50 of high quality. The main ocular and visual effects were computer vision syndrome, dry eye disease, and other isolated signs and symptoms. The main risk factors were the daily hours of VDT exposure, female gender, use of ophthalmic or contact lenses, increasing age, altered lighting conditions, and job seniority. Breaks, adequate workstation design, and ergonomic improvements were the main protective factors. Psychosocial factors and lifestyle behaviors also may influence ocular and visual health at work.</p><p><strong>Conclusions: </strong>Wide methodological variations were found, making it difficult to compare studies. Nevertheless, an evidence-informed conceptual mapping has been proposed that could be used as a starting point to guide preventive measures in VDT work settings. Further research with appropriate epidemiological designs is needed to establish causal relationships or determine temporal sequences between exposures and outcomes.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12788861/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145805012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medicine at work: a qualitative study into patients' experiences with medication self-management and burden in the context of work. 工作中的医学:一项关于患者在工作环境中药物自我管理和负担经验的定性研究。
IF 2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-06 DOI: 10.1093/joccuh/uiaf079
Eva Aalbers, Marcia Vervloet, Hennie Boeije, Liset van Dijk, Jany Rademakers

Objectives: The number of people with a chronic condition in the workforce is rising and the majority use medication. Medication self-management at work might be problematic. This study aimed to provide insight into the experiences of employees with balancing medication self-management and work.

Methods: Semi-structured interviews were held with 18 individuals with a variety of chronic health conditions, occupations, and medications. Interviews were guided by a topic list, transcribed, and open-coded. Thematic analysis identified determinants and behaviors that play a role in the interaction between medication self-management and performance and well-being at work.

Results: Fifteen participants used medication at work, mostly as needed and often administered on the go or covertly. Medication use at work was often perceived as doable due to flexibility and already established routines. However, a cumulative complexity of integrating medication use into the workday, the degree of side effects, and people's attitude towards openness could hinder successful integration of medication self-management at work. Participants adapted their medication schedule, made adjustments during their workday, and/or found ways to cope with these challenges emotionally. Medication often enabled work participation, although side effects of medication could impact workability, and (anticipated) stigma could affect the extent to which people can be themselves at work.

Conclusions: Medication self-management at work requires adaptability from individuals themselves, their colleagues, and employers. Fostering a culture of acceptance and understanding at work while providing practical support can enhance medication self-management practices and well-being at work.

目标:劳动力中患有慢性病的人数正在上升,大多数人使用药物治疗。工作中的药物自我管理可能会有问题。本研究旨在了解员工平衡用药自我管理与工作的经验。方法:采用半结构化访谈法对18名慢性健康状况、职业和用药情况不同的个体进行访谈。访谈以主题清单为指导,经过转录和开放编码。专题分析确定了在药物自我管理与工作绩效和福祉之间的相互作用中发挥作用的决定因素和行为。结果:15名参与者在工作中使用药物,大多是根据需要,经常在旅途中或秘密地使用药物。在工作中使用药物通常被认为是可行的,因为灵活性和已经建立的惯例。然而,将药物使用整合到工作中的累积复杂性、副作用程度和人们对开放性的态度可能会阻碍药物自我管理在工作中的成功整合。参与者调整他们的药物时间表,在他们的工作日做出调整,和/或找到应对这些挑战的方法。虽然药物的副作用会影响工作的可操作性,而且(预期的)耻辱感会影响人们在工作中做自己的程度,但药物通常能使人们参与工作。结论:工作中的药物自我管理需要个体自身、同事和雇主的适应性。在提供实际支持的同时,在工作中培养一种接受和理解的文化,可以提高男同性恋者的行为和工作幸福感。
{"title":"Medicine at work: a qualitative study into patients' experiences with medication self-management and burden in the context of work.","authors":"Eva Aalbers, Marcia Vervloet, Hennie Boeije, Liset van Dijk, Jany Rademakers","doi":"10.1093/joccuh/uiaf079","DOIUrl":"10.1093/joccuh/uiaf079","url":null,"abstract":"<p><strong>Objectives: </strong>The number of people with a chronic condition in the workforce is rising and the majority use medication. Medication self-management at work might be problematic. This study aimed to provide insight into the experiences of employees with balancing medication self-management and work.</p><p><strong>Methods: </strong>Semi-structured interviews were held with 18 individuals with a variety of chronic health conditions, occupations, and medications. Interviews were guided by a topic list, transcribed, and open-coded. Thematic analysis identified determinants and behaviors that play a role in the interaction between medication self-management and performance and well-being at work.</p><p><strong>Results: </strong>Fifteen participants used medication at work, mostly as needed and often administered on the go or covertly. Medication use at work was often perceived as doable due to flexibility and already established routines. However, a cumulative complexity of integrating medication use into the workday, the degree of side effects, and people's attitude towards openness could hinder successful integration of medication self-management at work. Participants adapted their medication schedule, made adjustments during their workday, and/or found ways to cope with these challenges emotionally. Medication often enabled work participation, although side effects of medication could impact workability, and (anticipated) stigma could affect the extent to which people can be themselves at work.</p><p><strong>Conclusions: </strong>Medication self-management at work requires adaptability from individuals themselves, their colleagues, and employers. Fostering a culture of acceptance and understanding at work while providing practical support can enhance medication self-management practices and well-being at work.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12965809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145959771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive urinary metabolite profiles of workers exposed to aniline, 2,4-dimethylaniline, and 2-methylaniline. 暴露于苯胺、2,4-二甲基苯胺和2-甲基苯胺的工人的综合尿液代谢物谱。
IF 2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-06 DOI: 10.1093/joccuh/uiaf072
Yoko Eitaki, Makiko Nakano, Kazuyuki Omae, Toru Takebayashi

Objectives: Biological exposure monitoring is particularly useful for understanding skin absorption of hazardous substances; however, existing measurement methods for aromatic amines show room for improvement, as they focus only on unchanged compounds. This study aimed to determine urinary concentrations of the unchanged compounds and metabolites of 3 aromatic amines (aniline, 2,4-dimethylaniline [m-xylidine], and 2-methylaniline [o-toluidine]) following enzymatic hydrolysis pretreatment, to calculate their proportions, and to assess markers for occupational biological exposure monitoring.

Methods: Urine samples were collected at the end of work shifts on consecutive days from 11 workers at a plant handling aromatic amines. Samples were enzymatically hydrolyzed using glucuronidase and sulfatase. The urinary concentrations of 25 substances were determined using liquid chromatography-tandem mass spectrometry.

Results: After exposure to the 3 aromatic amines, the major urinary excretion types were benzene ring-hydroxylated compounds, ring-hydroxylated and N-acetylated compounds, and side-chain methyl group oxides. The presence of unchanged and N-acetylated compounds was minor. Metabolism and urinary excretion were relatively different between the workers in our study and reported values from animal studies.

Conclusions: Excluding metabolites with low specificity, the sum of unchanged compounds and primary metabolites in urine could be a useful marker for biological exposure monitoring. Regarding aniline exposure, the relevant markers are the sum of aniline, N-acetyl-4-hydroxyaniline, and 2-hydroxyaniline. For 2,4-dimethylaniline exposure, the markers are the sum of 2,4-dimethylaniline, N-acetyl-4-carboxy-2-methylaniline, and 6-hydroxy-2,4-dimethylaniline. For 2-methylaniline exposure, the markers are the sum of 2-methylaniline, N-acetyl-4-hydroxy-2-methylaniline, 4-hydroxy-2-methylaniline, and 6-hydroxy-2-methylaniline. Urine sampling is recommended at the end of work shifts on consecutive working days.

目的:生物暴露监测对了解皮肤对有害物质的吸收特别有用;然而,现有的芳香胺的测量方法显示出改进的空间,因为它们只关注不变的化合物。本研究旨在测定三种芳香胺(苯胺、2,4-二甲基苯胺[m-二甲苯胺]和2-甲基苯胺[邻甲苯胺])在酶解预处理后尿液中未改变的化合物和代谢物的浓度,计算它们的比例,并评估职业生物暴露监测的标志物。方法:对某芳香胺处理厂11名工人在连续工作日轮班结束时进行尿样采集。用葡萄糖醛酸酶和硫酸酯酶对样品进行酶解。采用液相色谱-串联质谱法测定尿液中25种物质的浓度。结果:暴露于3种芳香胺后,尿中主要的排泄类型为苯环羟基化化合物、环羟基化和n -乙酰化化合物以及侧链甲基氧化物。未改变和n -乙酰化化合物的存在是次要的。工人的代谢和尿排泄与动物实验的报告值相对不同。结论:排除低特异性代谢物,尿液中未变化化合物和主要代谢物的总和可作为生物暴露监测的有用标志物。对于苯胺暴露,相关标记是苯胺、n -乙酰-4-羟基苯胺和2-羟基苯胺的总和。对于2,4-二甲基苯胺暴露,标记是2,4-二甲基苯胺,n -乙酰-4-羧基-2-甲基苯胺和6-羟基-2,4-二甲基苯胺的总和。对于2-甲基苯胺暴露,标记是2-甲基苯胺、n -乙酰-4-羟基-2-甲基苯胺、4-羟基-2-甲基苯胺和6-羟基-2-甲基苯胺的总和。建议在连续工作天的轮班结束时进行尿液取样。
{"title":"Comprehensive urinary metabolite profiles of workers exposed to aniline, 2,4-dimethylaniline, and 2-methylaniline.","authors":"Yoko Eitaki, Makiko Nakano, Kazuyuki Omae, Toru Takebayashi","doi":"10.1093/joccuh/uiaf072","DOIUrl":"10.1093/joccuh/uiaf072","url":null,"abstract":"<p><strong>Objectives: </strong>Biological exposure monitoring is particularly useful for understanding skin absorption of hazardous substances; however, existing measurement methods for aromatic amines show room for improvement, as they focus only on unchanged compounds. This study aimed to determine urinary concentrations of the unchanged compounds and metabolites of 3 aromatic amines (aniline, 2,4-dimethylaniline [m-xylidine], and 2-methylaniline [o-toluidine]) following enzymatic hydrolysis pretreatment, to calculate their proportions, and to assess markers for occupational biological exposure monitoring.</p><p><strong>Methods: </strong>Urine samples were collected at the end of work shifts on consecutive days from 11 workers at a plant handling aromatic amines. Samples were enzymatically hydrolyzed using glucuronidase and sulfatase. The urinary concentrations of 25 substances were determined using liquid chromatography-tandem mass spectrometry.</p><p><strong>Results: </strong>After exposure to the 3 aromatic amines, the major urinary excretion types were benzene ring-hydroxylated compounds, ring-hydroxylated and N-acetylated compounds, and side-chain methyl group oxides. The presence of unchanged and N-acetylated compounds was minor. Metabolism and urinary excretion were relatively different between the workers in our study and reported values from animal studies.</p><p><strong>Conclusions: </strong>Excluding metabolites with low specificity, the sum of unchanged compounds and primary metabolites in urine could be a useful marker for biological exposure monitoring. Regarding aniline exposure, the relevant markers are the sum of aniline, N-acetyl-4-hydroxyaniline, and 2-hydroxyaniline. For 2,4-dimethylaniline exposure, the markers are the sum of 2,4-dimethylaniline, N-acetyl-4-carboxy-2-methylaniline, and 6-hydroxy-2,4-dimethylaniline. For 2-methylaniline exposure, the markers are the sum of 2-methylaniline, N-acetyl-4-hydroxy-2-methylaniline, 4-hydroxy-2-methylaniline, and 6-hydroxy-2-methylaniline. Urine sampling is recommended at the end of work shifts on consecutive working days.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12788857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145677806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Different associations of stay-at-home exposure with changes in body mass index and cardiometabolic factors depending on occupational physical activity: a longitudinal quasi-experimental design. 基于职业体力活动的居家暴露与身体质量指数和心脏代谢因子变化的不同关联:纵向准实验设计
IF 2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-06 DOI: 10.1093/joccuh/uiaf069
Daijiro Kabata, Noriaki Kakiuchi, Takashi Marui, Naoko Ikeda, Mutsuko Kawai, Aki Kaimori, Noriko Saeki, Katsufumi Kajimoto, Riho Tanaka, Ayumi Zeniya, Fumi Yamanouchi, Saori Matsumiya, Yukihiro Koretsune

Objectives: To quantify the short-term impact of an unexpected stay-at-home exposure, caused by a shipment suspension, on body mass index (BMI) and cardiometabolic markers among employees with different levels of occupational physical activity.

Methods: Health-check records from 8307 workers at a large Japanese automobile manufacturer were linked to company attendance data covering a shipment suspension (January to April 2024). An interrupted time-series assessed BMI trajectories before, during, and after the halt. Among 614 employees who underwent an additional examination in April 2024, mixed-effects models related the duration of stay-at-home to changes in BMI and blood pressure within low-, medium-, and high-intensity job categories.

Results: Compared with pre-halt trends, medium-intensity and high-intensity workers showed significant level rises in BMI (0.96 kg/m2; 95% CI, 0.56-1.36; and 0.64 kg/m2; 95% CI, 0.24-1.04, respectively) at the onset of the suspension. Mixed-effects analyses showed a positive dose-response between the duration of stay-at-home and BMI gain in high-intensity jobs (0.47 kg/m2 per 20% absent days; 95% CI, 0.37-0.58). Per 20% of scheduled workdays absent, systolic blood pressure was higher in the medium- and high-intensity groups. No significant effects were observed among sedentary workers.

Conclusions: Employees whose daily energy expenditure relies on job-related physical activity are especially susceptible to weight gain and blood pressure elevations during forced work interruptions. Business continuity plans should embed tailored countermeasures-such as structured exercise programs and phased returns to on-site duties-to safeguard metabolic health during future operational disruptions.

目的:量化运输暂停导致的意外在家暴露对不同职业体力活动水平员工的身体质量指数(BMI)和心脏代谢指标的短期影响。方法:将日本一家大型汽车制造商8307名工人的健康检查记录与公司出勤数据(涵盖出货暂停(2024年1月至4月))联系起来。一个中断的时间序列评估了暂停之前、期间和之后的BMI轨迹。在2024年4月接受额外检查的614名员工中,混合效应模型将低、中、高强度工作类别的在家工作时间与BMI和血压的变化联系起来。结果:与暂停前的趋势相比,中强度和高强度工人在暂停开始时的水平显著上升(0.96 kg/m2; 95% CI分别为0.56 ~ 1.36和0.64 kg/m2; 95% CI分别为0.24 ~ 1.04)。混合效应分析显示,在高强度工作中,呆在家里的时间与BMI增加之间存在正剂量反应(每20%缺勤日0.47 kg/m2; 95% CI 0.37-0.58)。中等强度和高强度锻炼组的收缩压在每20%的休假工作日中较高。在久坐不动的员工中没有观察到明显的影响。结论:日常能量消耗依赖于与工作相关的体力活动的员工在被迫中断工作时特别容易体重增加和血压升高。业务连续性计划应该包含量身定制的应对措施,例如有组织的锻炼计划和分阶段返回现场工作,以在未来的运营中断中保障代谢健康。
{"title":"Different associations of stay-at-home exposure with changes in body mass index and cardiometabolic factors depending on occupational physical activity: a longitudinal quasi-experimental design.","authors":"Daijiro Kabata, Noriaki Kakiuchi, Takashi Marui, Naoko Ikeda, Mutsuko Kawai, Aki Kaimori, Noriko Saeki, Katsufumi Kajimoto, Riho Tanaka, Ayumi Zeniya, Fumi Yamanouchi, Saori Matsumiya, Yukihiro Koretsune","doi":"10.1093/joccuh/uiaf069","DOIUrl":"10.1093/joccuh/uiaf069","url":null,"abstract":"<p><strong>Objectives: </strong>To quantify the short-term impact of an unexpected stay-at-home exposure, caused by a shipment suspension, on body mass index (BMI) and cardiometabolic markers among employees with different levels of occupational physical activity.</p><p><strong>Methods: </strong>Health-check records from 8307 workers at a large Japanese automobile manufacturer were linked to company attendance data covering a shipment suspension (January to April 2024). An interrupted time-series assessed BMI trajectories before, during, and after the halt. Among 614 employees who underwent an additional examination in April 2024, mixed-effects models related the duration of stay-at-home to changes in BMI and blood pressure within low-, medium-, and high-intensity job categories.</p><p><strong>Results: </strong>Compared with pre-halt trends, medium-intensity and high-intensity workers showed significant level rises in BMI (0.96 kg/m2; 95% CI, 0.56-1.36; and 0.64 kg/m2; 95% CI, 0.24-1.04, respectively) at the onset of the suspension. Mixed-effects analyses showed a positive dose-response between the duration of stay-at-home and BMI gain in high-intensity jobs (0.47 kg/m2 per 20% absent days; 95% CI, 0.37-0.58). Per 20% of scheduled workdays absent, systolic blood pressure was higher in the medium- and high-intensity groups. No significant effects were observed among sedentary workers.</p><p><strong>Conclusions: </strong>Employees whose daily energy expenditure relies on job-related physical activity are especially susceptible to weight gain and blood pressure elevations during forced work interruptions. Business continuity plans should embed tailored countermeasures-such as structured exercise programs and phased returns to on-site duties-to safeguard metabolic health during future operational disruptions.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12788860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145634893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differences in Perceived Return-to-Work Barriers Between Manual and Non-Manual Workers. 体力劳动者和非体力劳动者对重返工作障碍的感知差异。
IF 2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-24 DOI: 10.1093/joccuh/uiaf075
Shunsuke Inoue, Seiichiro Tateishi, Arisa Harada, Etsuko Hosoda, Masako Nagata, Koji Mori

Background: Return-to-work (RTW) support has become a growing priority in occupational health. Manual workers-who constitute over half of the global labor force-may face greater RTW barriers due to the physically demanding nature of their jobs. However, few studies have quantitatively compared the perceived RTW barriers between manual and non-manual workers. This study aimed to compare perceived RTW barriers between manual and non-manual workers with chronic conditions to inform the development of tailored support strategies.

Methods: We analyzed 219 employed adults, either actively working or on certified leave, who attended X Hospital consultations between September 2019 and June 2020 to obtain support for balancing work and medical treatment. Perceived RTW barriers were assessed with a validated 10-category yes/no structured checklist (personal: work ability/psychological/health literacy; workplace: structure/system/support; inter-sectoral/social). Logistic regression was performed to compare barriers between manual and non-manual workers.

Results: Manual workers were significantly more likely to report barriers related to psychological impacts (OR = 2.34) and workplace systems (OR = 2.88). Although work ability did not differ significantly by job type, it was the most frequently reported RTW barrier in both groups.

Conclusion: Manual workers' RTW challenges are characterized by psychological and organizational barriers. RTW programs should assess psychological readiness before resumption of duties and provide managerial training to address anxiety and loss of confidence, while implementing job-specific accommodations such as phased tasks, ergonomic adjustments, and light duties in coordination with healthcare providers.

背景:支持重返工作岗位(RTW)已成为职业卫生领域越来越重要的优先事项。体力劳动者占全球劳动力的一半以上,由于他们的工作需要体力,他们可能面临更大的环球旅行障碍。然而,很少有研究对体力劳动者和非体力劳动者之间感知的RTW障碍进行定量比较。本研究旨在比较慢性体力劳动者和非体力劳动者之间感知的RTW障碍,为制定量身定制的支持策略提供信息。方法:我们分析了2019年9月至2020年6月期间在X医院就诊的219名在职成年人,他们要么在积极工作,要么在带证休假,以获得平衡工作和医疗的支持。感知到的RTW障碍通过一个有效的10类是/否结构化清单进行评估(个人:工作能力/心理/健康素养;工作场所:结构/系统/支持;跨部门/社会)。采用逻辑回归比较体力劳动者和非体力劳动者之间的障碍。结果:体力劳动者更有可能报告与心理影响(OR = 2.34)和工作场所制度(OR = 2.88)相关的障碍。虽然工作能力在工作类型上没有显著差异,但它是两组中最常见的RTW障碍。结论:体力劳动者的RTW挑战主要表现为心理障碍和组织障碍。RTW计划应在恢复工作前评估心理准备情况,并提供管理培训,以解决焦虑和信心丧失问题,同时实施特定工作的适应措施,如分阶段任务、人体工程学调整和与医疗保健提供者协调的轻职责。
{"title":"Differences in Perceived Return-to-Work Barriers Between Manual and Non-Manual Workers.","authors":"Shunsuke Inoue, Seiichiro Tateishi, Arisa Harada, Etsuko Hosoda, Masako Nagata, Koji Mori","doi":"10.1093/joccuh/uiaf075","DOIUrl":"https://doi.org/10.1093/joccuh/uiaf075","url":null,"abstract":"<p><strong>Background: </strong>Return-to-work (RTW) support has become a growing priority in occupational health. Manual workers-who constitute over half of the global labor force-may face greater RTW barriers due to the physically demanding nature of their jobs. However, few studies have quantitatively compared the perceived RTW barriers between manual and non-manual workers. This study aimed to compare perceived RTW barriers between manual and non-manual workers with chronic conditions to inform the development of tailored support strategies.</p><p><strong>Methods: </strong>We analyzed 219 employed adults, either actively working or on certified leave, who attended X Hospital consultations between September 2019 and June 2020 to obtain support for balancing work and medical treatment. Perceived RTW barriers were assessed with a validated 10-category yes/no structured checklist (personal: work ability/psychological/health literacy; workplace: structure/system/support; inter-sectoral/social). Logistic regression was performed to compare barriers between manual and non-manual workers.</p><p><strong>Results: </strong>Manual workers were significantly more likely to report barriers related to psychological impacts (OR = 2.34) and workplace systems (OR = 2.88). Although work ability did not differ significantly by job type, it was the most frequently reported RTW barrier in both groups.</p><p><strong>Conclusion: </strong>Manual workers' RTW challenges are characterized by psychological and organizational barriers. RTW programs should assess psychological readiness before resumption of duties and provide managerial training to address anxiety and loss of confidence, while implementing job-specific accommodations such as phased tasks, ergonomic adjustments, and light duties in coordination with healthcare providers.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145819717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occupation as a risk factor for progression of chronic kidney disease: retrospective cohort study. 职业是慢性肾脏疾病进展的危险因素:回顾性队列研究
IF 2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-19 DOI: 10.1093/joccuh/uiaf074
Daisuke Takada, Susumu Kunisawa, Akira Kikuno, Tomoko Iritani, Yuichi Imanaka

Objectives The cause of chronic kidney disease (CKD) remains uncertain in the majority of affected individuals, and risk of socioeconomic status on CKD progression has recently gained attention. We compared the risk of CKD progression among 18 occupational classifications using an annual health-checkup database. Methods We used the annual health checkup data and health insurance claims data of the Japan Health Insurance Association in Kyoto prefecture between April 2012 and March 2016. The primary outcome for survival analysis was defined as a more than 30% change in the estimated glomerular filtration rate (eGFR) from the first health checkup. We used the Cox proportional-hazards model for time-to-event analyses to estimate the hazard ratio, and 95% CIs for the primary outcome, adjusting for age, sex, eGFR, body mass index, blood pressure, blood sugar, dyslipidemia, uric acid, urinary protein, and existence of kidney diseases at first health checkup. Results We analyzed 239,506 employees, and 1,736 (0.7%) individuals whose eGFR had decreased by 30% or more; the mean follow-up period was 2.8 years. When we compared the risk for "manufacturing," five categories of industries ("information and communications"; "transport and postal services"; "accommodations, eating and drinking services"; "living-related and personal services and amusement service"; "medical, health care and welfare") were associated with a decline in the risk of eGFR after adjusting for the confounding factors and/or mediators. Conclusions We provided evidence that the risk of CKD progression depends on occupational type. Further research is needed to confirm the mechanism and causal relationships involved.

在大多数受影响的个体中,慢性肾脏疾病(CKD)的病因仍然不确定,社会经济地位对CKD进展的风险最近得到了关注。我们使用年度健康检查数据库比较了18种职业分类中CKD进展的风险。方法利用2012年4月至2016年3月日本健康保险协会在京都市的年度健康体检数据和健康保险理赔数据。生存分析的主要终点定义为第一次健康检查时估计的肾小球滤过率(eGFR)变化超过30%。在调整了年龄、性别、eGFR、体重指数、血压、血糖、血脂异常、尿酸、尿蛋白和首次健康检查时是否存在肾脏疾病等因素后,我们使用Cox比例风险模型进行事件时间分析,以估计风险比和主要结局的95% ci。结果我们分析了239,506名员工,其中1736名(0.7%)个体的eGFR下降了30%或更多;平均随访时间为2.8年。当我们比较“制造业”的风险时,在调整了混杂因素和/或中介因素后,五类行业(“信息和通信”、“运输和邮政服务”、“住宿、饮食服务”、“与生活相关的个人服务和娱乐服务”、“医疗、保健和福利”)与eGFR风险下降有关。结论:我们提供的证据表明CKD进展的风险取决于职业类型。需要进一步的研究来证实其机制和因果关系。
{"title":"Occupation as a risk factor for progression of chronic kidney disease: retrospective cohort study.","authors":"Daisuke Takada, Susumu Kunisawa, Akira Kikuno, Tomoko Iritani, Yuichi Imanaka","doi":"10.1093/joccuh/uiaf074","DOIUrl":"https://doi.org/10.1093/joccuh/uiaf074","url":null,"abstract":"<p><p>Objectives The cause of chronic kidney disease (CKD) remains uncertain in the majority of affected individuals, and risk of socioeconomic status on CKD progression has recently gained attention. We compared the risk of CKD progression among 18 occupational classifications using an annual health-checkup database. Methods We used the annual health checkup data and health insurance claims data of the Japan Health Insurance Association in Kyoto prefecture between April 2012 and March 2016. The primary outcome for survival analysis was defined as a more than 30% change in the estimated glomerular filtration rate (eGFR) from the first health checkup. We used the Cox proportional-hazards model for time-to-event analyses to estimate the hazard ratio, and 95% CIs for the primary outcome, adjusting for age, sex, eGFR, body mass index, blood pressure, blood sugar, dyslipidemia, uric acid, urinary protein, and existence of kidney diseases at first health checkup. Results We analyzed 239,506 employees, and 1,736 (0.7%) individuals whose eGFR had decreased by 30% or more; the mean follow-up period was 2.8 years. When we compared the risk for \"manufacturing,\" five categories of industries (\"information and communications\"; \"transport and postal services\"; \"accommodations, eating and drinking services\"; \"living-related and personal services and amusement service\"; \"medical, health care and welfare\") were associated with a decline in the risk of eGFR after adjusting for the confounding factors and/or mediators. Conclusions We provided evidence that the risk of CKD progression depends on occupational type. Further research is needed to confirm the mechanism and causal relationships involved.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145781346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and Validation of Brief Measures of Workplace Loneliness. 工作场所孤独感简要测量方法的开发与验证。
IF 2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-27 DOI: 10.1093/joccuh/uiaf068
Izumi Ayase, Akihito Shimazu, Masahito Tokita, Kentaro Sakamaki, Norito Kawakami

Objectives: This study aimed to develop and validate two concise measures of workplace loneliness.

Methods: A three-item scale for loneliness at work (SLAW-3) and a single-item scale for loneliness at work (SLAW-1) were developed by modifying existing scales for general loneliness. A cross-sectional online survey was conducted of 1,228 full-time employees in Japan to test the reliability and validity of these scales. Internal consistency of the SLAW-3 was assessed using Cronbach's alpha coefficient, and the construct validity was examined through correlations with established measures of workplace loneliness, psychological distress, well-being, self-rated health, and workplace social support.

Results: The SLAW-3 demonstrated strong internal consistency (Cronbach's alpha = 0.91) and unidimensionality. It correlated positively with established measures of workplace loneliness and psychological distress measures and negatively with well-being and workplace social support measures. The SLAW-1 also demonstrated significant correlation with the SLAW-3 and with psychological indicators such as distress, well-being, self-rated health, and workplace social support.

Conclusions: The SLAW-3 was found to be a reliable and valid measure of workplace loneliness. The SLAW-1 also demonstrated adequate construct validity, despite its single-item format. Both scales are short and may be effectively used to assess workplace loneliness in large-scale employee surveys or brief screenings.

目的:本研究旨在开发和验证两种简洁的职场孤独感测量方法。方法:通过对现有一般孤独感量表的修改,编制工作孤独感量表(SLAW-3)和工作孤独感量表(SLAW-1)。我们对日本的1228名全职员工进行了横断面在线调查,以检验这些量表的信度和效度。采用Cronbach’s alpha系数评估SLAW-3的内部一致性,并通过与工作场所孤独感、心理困扰、幸福感、自评健康和工作场所社会支持等已建立的测量指标的相关性来检验结构效度。结果:SLAW-3具有较强的内部一致性(Cronbach’s alpha = 0.91)和单一性。它与既定的工作场所孤独感和心理困扰测量呈正相关,与幸福感和工作场所社会支持测量呈负相关。SLAW-1与SLAW-3以及心理指标(如痛苦、幸福、自评健康和工作场所社会支持)也表现出显著的相关性。结论:SLAW-3量表是一种可靠、有效的职场孤独感测评方法。SLAW-1也显示出足够的结构效度,尽管它是单项目格式。这两个量表都很短,可以有效地用于大规模员工调查或简短筛选中评估工作场所的孤独感。
{"title":"Development and Validation of Brief Measures of Workplace Loneliness.","authors":"Izumi Ayase, Akihito Shimazu, Masahito Tokita, Kentaro Sakamaki, Norito Kawakami","doi":"10.1093/joccuh/uiaf068","DOIUrl":"https://doi.org/10.1093/joccuh/uiaf068","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to develop and validate two concise measures of workplace loneliness.</p><p><strong>Methods: </strong>A three-item scale for loneliness at work (SLAW-3) and a single-item scale for loneliness at work (SLAW-1) were developed by modifying existing scales for general loneliness. A cross-sectional online survey was conducted of 1,228 full-time employees in Japan to test the reliability and validity of these scales. Internal consistency of the SLAW-3 was assessed using Cronbach's alpha coefficient, and the construct validity was examined through correlations with established measures of workplace loneliness, psychological distress, well-being, self-rated health, and workplace social support.</p><p><strong>Results: </strong>The SLAW-3 demonstrated strong internal consistency (Cronbach's alpha = 0.91) and unidimensionality. It correlated positively with established measures of workplace loneliness and psychological distress measures and negatively with well-being and workplace social support measures. The SLAW-1 also demonstrated significant correlation with the SLAW-3 and with psychological indicators such as distress, well-being, self-rated health, and workplace social support.</p><p><strong>Conclusions: </strong>The SLAW-3 was found to be a reliable and valid measure of workplace loneliness. The SLAW-1 also demonstrated adequate construct validity, despite its single-item format. Both scales are short and may be effectively used to assess workplace loneliness in large-scale employee surveys or brief screenings.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145634928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sickness absence due to common mental disorders and antidepressant prescription among health and social care workers during as compared to before the COVID-19 pandemic - a nationwide register study of the Swedish population. 与2019冠状病毒病大流行之前相比,卫生和社会护理工作者中因常见精神障碍和抗抑郁药物处方而缺勤的情况——一项瑞典全国人口登记研究。
IF 2 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-25 DOI: 10.1093/joccuh/uiaf067
Stefanie Kirchner, Katalin Gémes, Pontus Josefsson, Josep Maria Haro, Mireia Felez-Nobrega, Heidi Taipale, Marit Sijbrandij, Anke B Witteveen, Maria Melchior, Giulia Caggiu, Claudia Conflitti, Antonio Lora, Matteo Monzio Compagnoni, Jakob Bergström, Ellenor Mittendorfer-Rutz

Objectives: Essential workers, particularly in healthcare and social services were critical during the peak of the COVID-19 pandemic, yet their mental health outcomes remain understudied. We examined changes in (i) sickness absence (SA) due to common mental disorders (CMDs) and (ii) antidepressant prescription in health and social care workers during vs. pre-pandemic periods.

Methods: Using Swedish national registers, we included healthcare and social workers (19 - 65 years) from 2018 to 2021. We compared quarterly incidence rate (IR) trends for SA >90 days due to CMD and antidepressant prescription across two periods: pre-pandemic (Jan 2018-Feb 2020) and during the pandemic (Mar 2020-Dec 2021) using interrupted time-series analysis. Analyses accounted for seasonality and were stratified by age, sex, and education.

Results: There was no evidence of a difference in IR trends for SA >90 days or antidepressant prescription pre-pandemic vs. during the pandemic for the entire sector. However, trends of IR for antidepressant prescription increased among workers in medical laboratories (8.7% per quarter change; 4.4-13.1%), and hospitals (1.5%; 0.6-2.5%) and decreased per quarter for ambulance transports (5.4%; 0.4-1.0%). Women (10.9%; 7.2-14.7%) and highly educated individuals (10.0%; 4.1-16.1%) working in medical laboratories as well as 19-25-year-olds working in primary and dental care (7.3%; 1.7-13.1%) also experienced an increase in antidepressant prescription.

Conclusions: While overall trends in SA >90 days and antidepressant prescription remained stable, certain occupational and sociodemographic groups were found to be affected in regard to antidepressant prescription. These groups warrant targeted support in future health crises.

目标:在2019冠状病毒病大流行高峰期,基层工作者,特别是医疗保健和社会服务工作者至关重要,但他们的心理健康结果仍未得到充分研究。我们检查了(i)常见精神障碍(cmd)导致的缺勤(SA)和(ii)卫生和社会保健工作者在与大流行前相比的抗抑郁药物处方方面的变化。方法:使用瑞典国家登记册,我们纳入了2018年至2021年的医疗保健和社会工作者(19 - 65岁)。我们使用中断时间序列分析比较了两个时期(大流行前(2018年1月至2020年2月)和大流行期间(2020年3月至2021年12月)由于CMD和抗抑郁药处方导致的SA bbb90天的季度发病率(IR)趋势。分析考虑了季节性因素,并按年龄、性别和教育程度分层。结果:在整个行业,没有证据表明SA在流行前90天的IR趋势或抗抑郁药物处方与流行期间的IR趋势存在差异。然而,医学实验室工作人员抗抑郁药处方的IR趋势增加(每季度变化8.7%;4.4-13.1%),医院(1.5%;0.6-2.5%),救护车运输的IR趋势下降(5.4%;0.4-1.0%)。在医学实验室工作的妇女(10.9%;7.2-14.7%)和受过高等教育的个人(10.0%;4.1-16.1%)以及在初级保健和牙科保健工作的19-25岁的人(7.3%;1.7-13.1%)也经历了抗抑郁药处方的增加。结论:虽然SA bbb90天和抗抑郁药物处方的总体趋势保持稳定,但某些职业和社会人口统计学群体在抗抑郁药物处方方面受到影响。在今后的卫生危机中,这些群体需要得到有针对性的支持。
{"title":"Sickness absence due to common mental disorders and antidepressant prescription among health and social care workers during as compared to before the COVID-19 pandemic - a nationwide register study of the Swedish population.","authors":"Stefanie Kirchner, Katalin Gémes, Pontus Josefsson, Josep Maria Haro, Mireia Felez-Nobrega, Heidi Taipale, Marit Sijbrandij, Anke B Witteveen, Maria Melchior, Giulia Caggiu, Claudia Conflitti, Antonio Lora, Matteo Monzio Compagnoni, Jakob Bergström, Ellenor Mittendorfer-Rutz","doi":"10.1093/joccuh/uiaf067","DOIUrl":"https://doi.org/10.1093/joccuh/uiaf067","url":null,"abstract":"<p><strong>Objectives: </strong>Essential workers, particularly in healthcare and social services were critical during the peak of the COVID-19 pandemic, yet their mental health outcomes remain understudied. We examined changes in (i) sickness absence (SA) due to common mental disorders (CMDs) and (ii) antidepressant prescription in health and social care workers during vs. pre-pandemic periods.</p><p><strong>Methods: </strong>Using Swedish national registers, we included healthcare and social workers (19 - 65 years) from 2018 to 2021. We compared quarterly incidence rate (IR) trends for SA >90 days due to CMD and antidepressant prescription across two periods: pre-pandemic (Jan 2018-Feb 2020) and during the pandemic (Mar 2020-Dec 2021) using interrupted time-series analysis. Analyses accounted for seasonality and were stratified by age, sex, and education.</p><p><strong>Results: </strong>There was no evidence of a difference in IR trends for SA >90 days or antidepressant prescription pre-pandemic vs. during the pandemic for the entire sector. However, trends of IR for antidepressant prescription increased among workers in medical laboratories (8.7% per quarter change; 4.4-13.1%), and hospitals (1.5%; 0.6-2.5%) and decreased per quarter for ambulance transports (5.4%; 0.4-1.0%). Women (10.9%; 7.2-14.7%) and highly educated individuals (10.0%; 4.1-16.1%) working in medical laboratories as well as 19-25-year-olds working in primary and dental care (7.3%; 1.7-13.1%) also experienced an increase in antidepressant prescription.</p><p><strong>Conclusions: </strong>While overall trends in SA >90 days and antidepressant prescription remained stable, certain occupational and sociodemographic groups were found to be affected in regard to antidepressant prescription. These groups warrant targeted support in future health crises.</p>","PeriodicalId":16632,"journal":{"name":"Journal of Occupational Health","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145604307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Occupational Health
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1