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Hydrocarbon production potential of paralic reservoirs from the Niger Delta basin: Evidence from ichnological studies 尼日尔三角洲盆地副岩储层的碳氢化合物生产潜力:岩石学研究的证据
Pub Date : 2024-05-14 DOI: 10.4314/sa.v23i2.8
O.O. Efemena, C. Ugwueze
Reservoir ichnological study was employed to improve on the inconsistencies and poor interpretation of hydrocarbon-bearing strata within the multipartite maturing terrain of the onshore Niger Delta basin. Ichnofacies characterization revealed two distinctive trace fossil suites that both reflected different feeding behaviours and responses to substrate consistency, which assisted in the high-resolution assessment of facies constituting the paralic reservoirs. Fifteen potential reservoir intervals were subdivided into productive and non-productive as revealed on core slabs as well as well log signatures. Fluctuating river sediment influx has been considered to be detrimental to the colonization of the channel deposits and barrier bars, which resulted in excellent hydrocarbon reservoirs in the study area. The sandstone facies, characterized by sparse bioturbation and extensive bedding, displays imprints of Ophiomorpha, Thalassinoides, and Palaeophycus. The removal of these imprints has minimized subtle heterogeneities, resulting in more uniform reservoir characteristics. This uniformity has favored the accumulation of hydrocarbons within the point bars.Biogenicchurning of bedded sediment generated a poorer sorting index thereby reducing the reservoir quality at 9866-9840ft, 9154-9120ft, and 9090- 060ft depth intervals, which has been interpreted to represent poor reservoir potentials. However, it is advised that future investigations should focus on the forced regressive shoreface and delta front reservoirs of the studied interval for its internal continuity that may contain maximum production potential. 
采用储层痕量化石研究来改善尼日尔三角洲陆上盆地多岩层成熟地形中含烃地层的不一致性和解释不清的问题。痕量化石特征研究揭示了两种截然不同的痕量化石组合,它们都反映了不同的取食行为和对基质一致性的反应,这有助于对构成副岩储层的岩相进行高分辨率评估。根据岩心板和测井记录的特征,将 15 个潜在储层区间细分为生产性和非生产性储层。波动的河流沉积物流入量被认为不利于河道沉积物和屏障条石的定殖,这导致了研究区域极佳的碳氢化合物储层。砂岩面具有稀疏的生物扰动和广泛的层理特征,显示出 Ophiomorpha、Thalassinoides 和 Palaeophycus 的印记。这些印记的去除最大程度地减少了细微的异质性,从而使储层特征更加统一。这种均匀性有利于碳氢化合物在点条内的积累。层状沉积物的生物燃烧产生了较差的分选指数,从而降低了 9866-9840 英尺、9154-9120 英尺和 9090- 060 英尺深度区间的储层质量,这被解释为储层潜力较差。不过,建议今后的勘探工作应重点关注所研究区间的强制回归岸面和三角洲前沿储层,因为其内部连续性可能蕴含着最大的生产潜力。
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引用次数: 0
Anti-dyslipidemic and cardio-protective effects of dietary Vernonia amygdalina leaves in monosodium glutamate intoxicated high fat diet fed Wistar rats 谷氨酸钠中毒高脂饮食喂养的 Wistar 大鼠膳食中杏仁蕨叶的降血脂和心血管保护作用
Pub Date : 2024-05-14 DOI: 10.4314/sa.v23i2.13
E. E. Ubah, I. Ijeh, K. C. Oguamanam,, C. A. Obike, A. Egbuonu
The study evaluated the proximate analysis, anti- dyslipidemic and cardioprotective effects of dietary incorporated Vernonia amygdalina (VA) leaves in Monosodium glutamate (MSG) intoxicated High fat diet (HFD) fed Wistar rats. The proximate analysis of the leaves revealed the highest ash and carbohydrate content in the control (basal) diet, highest protein, crude fibre and moisture content in the 10% VA incorporated HFD and the highest crude fat in the HFD only group. Dietary incorporation of VA in HFD reversed the trend of hypercholesterolemia and hypertriglyceridemia observed in experimental animals after chronic MSG, HFD and MSG + HFD administration. At the end of week 8, HFD only group produced a higher level of total cholesterol and triglyceride when compared to the basal control diet group and the MSG only group while the 10% VA HFD group produced the greatest reduction in total cholesterol and triglyceride from week 9 – week 12. Possible mechanisms include the presence of crude fibers which binds to bile acids reducing the absorption of cholesterol. Histopathology studies of the myocardial tissues at the end of the study revealed in the MSG + HFD group signs of a marked diffused edema of the myocardium which was absent in the MSG only and HFD only groups while 5% and 10% VA incorporated HFD and the standard drug Orlistat 10 mg/kg failed to reverse the observed toxicity. Conclusion: Dietary VA reversed lipid derangement observed but failed to reverse myocardial histopathologies after chronic MSG + HFD administration and could be used as an adjunct for the treatment of obesity. 
该研究评估了谷氨酸钠(MSG)中毒高脂饮食(HFD)喂养的 Wistar 大鼠膳食中添加 Vernonia amygdalina(VA)叶片的近似物分析、抗血脂异常和心脏保护作用。叶片的近似物分析表明,对照组(基础)膳食中的灰分和碳水化合物含量最高,添加 10% VA 的高脂膳食中的蛋白质、粗纤维和水分含量最高,而仅添加高脂膳食组的粗脂肪含量最高。在高密度脂蛋白日粮中添加 VA 逆转了实验动物在长期摄入味精、高密度脂蛋白日粮和味精 + 高密度脂蛋白日粮之后观察到的高胆固醇血症和高甘油三酯血症的趋势。在第 8 周结束时,与基础控制饮食组和仅含味精组相比,仅含高密度脂蛋白饮食组产生的总胆固醇和甘油三酯水平更高,而从第 9 周到第 12 周,10% VA 高密度脂蛋白饮食组产生的总胆固醇和甘油三酯降幅最大。可能的机制包括粗纤维的存在与胆汁酸结合,减少了胆固醇的吸收。研究结束时对心肌组织进行的组织病理学研究显示,味精 + 高纤维食物组的心肌组织出现了明显的弥漫性水肿,而只有味精组和只有高纤维食物组的心肌组织则没有这种症状,而添加了高纤维食物和标准药物奥利司他 10 毫克/千克的 5% 和 10% VA 组则未能逆转观察到的毒性。结论膳食 VA 可逆转观察到的脂质紊乱,但未能逆转长期服用味精 + 高频分解食物后的心肌组织病理学,可用作治疗肥胖症的辅助药物。
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引用次数: 0
Integrated geophysical and geochemical characterization of hydrocarbon contaminated site in Erhoike-Kokori, Southern Nigeria 尼日利亚南部 Erhoike-Kokori 受碳氢化合物污染场地的综合地球物理和地球化学特征描述
Pub Date : 2024-05-14 DOI: 10.4314/sa.v23i2.19
O. S. Marere, O. J. Airen
The effectiveness of geophysical and geochemical methods in delineating hydrocarbon contamination in a spill site is carried out around theErhoike flow station in Kokori, Ethiope East LGA, Delta State. Wenner array was used for the transverse in acquiring the data which spanned a transverse of 200m and 3D model resistivity images were obtained from the inversion and presented in horizontal depth slices. Well water samples were also taken for Total Petroleum Hydrocarbon (TPH) content while soil samples from the location were also taken for Porosity and coefficient of permeability. The result of the 3D horizontal depth slices in the location reveals that Erhoike is impacted with hydrocarbon plume to a depth of 31.7m. The concentration of TPHCs from the water analysis shows that the wells around the suspected zones are affected by hydrocarbon. The laboratory tests for porosity (Փ ) and coefficient of permeability (k) for  the soil samples are indicative of sand/silty sand which thus allows the flow of PHCs plume to the soil and groundwater in the study area. The results of the study have shown that the soil is permeable and porous which would allow the passage of the leaked and spilled PHCs through the soil to groundwater where the PHCs could mix, float and sink into groundwater. The 3D analysis revealed the presence of PHCs up to a depth of 33.7m but prominent at a depth of 10m which indicates the presence of PHCs in the wells. The hydrochemical analysis also proved the same results as that of the 3D which authenticated the reliability of the method used in the study. 
在三角洲州 Ethiope East LGA 的 Kokori 的 Erhoike 流动站周围,对地球物理和地球化学方法在划定泄漏点碳氢化合物污染方面的有效性进行了研究。在获取横跨 200 米的数据时使用了温纳阵列,通过反演获得了三维电阻率模型图像,并以水平深度切片的形式呈现。还采集了井水样本以检测总石油烃 (TPH) 含量,同时采集了该地点的土壤样本以检测孔隙度和渗透系数。该地点的三维水平深度切片结果显示,Erhoike 受碳氢化合物羽流影响的深度为 31.7 米。水分析得出的 TPHCs 浓度表明,疑似区域周围的水井受到了碳氢化合物的影响。土壤样本的孔隙度(Փ)和渗透系数(k)的实验室测试表明,土壤样本为砂质/粉砂质,因此允许 PHCs 羽流进入研究区域的土壤和地下水。研究结果表明,土壤具有渗透性和多孔性,这使得泄漏和溢出的 PHC 可以通过土壤进入地下水,在地下水中混合、漂浮并沉入地下水。三维分析表明,在 33.7 米深的地方存在 PHCs,但在 10 米深的地方比较突出,这表明水井中存在 PHCs。水化学分析也证明了与三维分析相同的结果,这证明了研究中所使用方法的可靠性。
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引用次数: 0
Clinical laboratory techniques for detecting drugs of abuse: Feasibility in developing nations 检测滥用药物的临床实验室技术:发展中国家的可行性
Pub Date : 2024-05-14 DOI: 10.4314/sa.v23i2.31
O.G. Igharo, C.B.N. Akpata, G. A. AIKPITANYI-IDUITUA, T.J. Ime-Idim, O.E. Ero
Drugs of abuse are prescription, over-the-counter, or other forms of drugs that are often used for purposes other than those for which they are meant to be used, or in excessive amounts. The abuse of illicit drugs (for example cocaine, heroin, and codeine) poses a serious threat to public health, not to mention a great challenge to the health care system. It is important to review the techniques used in detecting these drugs of abuse to stay ahead of this growing global drug problem. This review aims to give an overview of known clinical laboratory techniques used in detecting some common drugs of abuse that could serve as an integral part of determining the presence of these drugs in bodily fluids and samples. Relevant literature was reviewed in various search engines (Google Scholar, PubMed, ScienceDirect, Bing). Findings showed that some of the current clinical laboratory techniques for detecting and quantifying drugs of abuse include Microcrystalline tests, thin-layer chromatography, colourimetric tests, immunoassays, urine dipstick tests, and ultraviolet spectroscopy. Apart from these known techniques, new and emerging techniques are being validated to serve as additions to these already existing techniques and be used in clinical settings. In conclusion, the burden of drug abuse is on the rise and becoming a public health concern. There should be an ever-increasing interest in developing new analytical methodologies not only to detect but also to quantify drugs of abuse which may be applied in a plethora of areas including clinical settings.Some of the outlined techniques are highly priced and for cost ineffectiveness, they may be difficult to afford and sustain in resource-restraint settings like developing nations. Hence, grants and laboratory infrastructural support may be needed from international donor agencies. 
滥用药物是指处方药、非处方药或其他形式的药物,这些药物经常被用于非预期目的或过量使用。非法药物(如可卡因、海洛因和可待因)的滥用对公众健康构成严重威胁,更不用说对医疗保健系统的巨大挑战了。为了应对这一日益严重的全球性毒品问题,回顾检测这些滥用药物的技术非常重要。本综述旨在概述用于检测一些常见滥用药物的已知临床实验室技术,这些技术可作为确定体液和样本中是否存在这些药物的组成部分。我们通过各种搜索引擎(Google Scholar、PubMed、ScienceDirect 和 Bing)查阅了相关文献。研究结果表明,目前用于检测和量化滥用药物的一些临床实验室技术包括微晶检测、薄层色谱法、比色法、免疫测定、尿液浸量测试和紫外光谱法。除这些已知技术外,新出现的技术也正在接受验证,以作为这些现有技术的补充,并在临床环境中使用。总之,药物滥用的负担在不断增加,已成为一个公共卫生问题。人们对开发新的分析方法的兴趣与日俱增,这些方法不仅能检测滥用药物,还能对其进行量化,可应用于包括临床环境在内的众多领域。因此,可能需要国际捐助机构提供赠款和实验室基础设施支持。
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引用次数: 0
Eclipse detection on variable star Ao Serpentis using Las Cumbres observatory global telescope (LCOGT) 利用拉斯坎布雷斯天文台全球望远镜(LCOGT)探测蛇夫座变星的日食情况
Pub Date : 2024-05-14 DOI: 10.4314/sa.v23i2.21
S. Esaenwi, O.J. Vwavware
To observe and document the distinctive eclipse phenomenon on the source, we conducted a photometric observation of the variable star AO Ser using the 0.4m SBIG optical telescope from the Las Cumbres Observatory Global Telescope Network remotely from Nigeria. On December 22, 2022, the LCOGT was used to observe the AO Ser data, and the telescope time was 120 minutes. Using SAO Image Viewer (DS9), VisieR, and IRIS software, we performed a photometric analysis on the eclipsing stellar data, allowing us to plot the light curve and infer eclipses. According to the outcome of our photometric analysis, AO Ser is an eclipsing binary variable star. The stellar analysis presented shows theaverage values of stellar eclipse parametersfrom the analysis of the Vfilterof AO Ser, asA1 = 1.37km, A2 = 0.329km, D1 = 188×103hrs (52.94secs), D2 = 79.4×103hrs (22.7secs) and d1 = 26.4×103hrs (7.65secs), d2 = 0hrs (0secs) respectively. For the B filter, the averagesof A1 = 0.65km, A2 = 0.145km, D1 = 185×103hrs (52.11secs), D2 = 76.6×103hrs (21.26.0secs), d1 = 26.0 ×103hrs (7.044secs) and d2 = 0hrs (0secs).The primary candidate of AO Ser is smaller than its secondary companion, as shown by the value of d2 = 0secs being the same for both V and B Filters observations. Two times during the orbit, when the primary passed in front of the secondary and when the secondary passed in front of the primary, the observed brightness decreased. The primary eclipse was designated as having a deeper peak than the secondary eclipse, which had a shallower peak. The percentage of the occulted stellar area and the stars' effective temperatures were used to calculate the size of the stellar brightness drop. 
为了观测和记录变星源上独特的日食现象,我们在尼日利亚利用拉斯坎布雷天文台全球望远镜网络的 0.4 米 SBIG 光学望远镜对变星 AO Ser 进行了远程光度观测。2022 年 12 月 22 日,利用 LCOGT 观测了 AO Ser 数据,望远镜观测时间为 120 分钟。我们使用 SAO 图像查看器(DS9)、VisieR 和 IRIS 软件对食恒星数据进行了测光分析,从而绘制出光曲线并推断出食。根据我们的测光分析结果,AO Ser 是一颗食双星变星。所提供的恒星分析显示了对 AO Ser 的 V 滤光片分析得出的恒星食参数平均值,分别为 A1 = 1.37km,A2 = 0.329km,D1 = 188×103hrs (52.94 秒),D2 = 79.4×103hrs (22.7 秒),d1 = 26.4×103hrs (7.65 秒),d2 = 0hrs (0 秒)。B 滤波器的平均值分别为:A1 = 0.65km,A2 = 0.145km,D1 = 185×103小时(52.11秒),D2 = 76.6×103小时(21.26.0秒),d1 = 26.0×103小时(7.044秒),d2 = 0小时(0秒)。AO Ser的主候选星小于它的副伴星,这一点可以从V滤波器和B滤波器观测到的d2 = 0秒值相同看出。在轨道上有两次,当主食经过副食前方和副食经过主食前方时,观测到的亮度都有所下降。主食的峰值比副食的峰值深,副食的峰值比主食的峰值浅。被掩星面积的百分比和恒星的有效温度被用来计算恒星亮度下降的大小。
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引用次数: 0
Empirical assessment of fuel-wood induced carbon footprint in Udu Local Government Area of Delta State, Nigeria 尼日利亚三角洲州乌杜地方政府地区薪材引起的碳足迹实证评估
Pub Date : 2024-05-14 DOI: 10.4314/sa.v23i2.7
J. Igben
Most studies of carbon footprint (CFP) in relation to climate change focus on the generation of greenhouse gases (GHG) by human activities such as electricity, industrialization and transportation in urban areas with little attention on rural areas. Against this background, this study aims to identify sources of Carbon dioxide (CO2) emission, and estimate the amount of CFP  generated through fuel-wood consumption in Udu LGA of Delta State, Nigeria. Data for the study were obtained from a sample of 200 households in four (4) rural settlements chosen randomly from 32 villages. Mixed survey technique which involved questionnaires, field observations and measurement were employed to collect data for the study. Data obtained were analysed using descriptive statistics, Pearson Correlation Analysis and calculation of CFP. The study reveals that the major source of CO2 emission was fuel wood (82.0%), which is used for various domestic and production activities with an average of 39.58kg consumed by each sampled household; thus, generating between 7.24314 MT daily. The amount of CFP also varies directly with the sizes of the sampled households. The study recommends that alternative sources of clean energy should be developed and utilized for sustainable development of the environment and mitigation of climate change phenomenon. 
与气候变化有关的碳足迹(CFP)研究大多集中在城市地区的电力、工业化和交通等人类活动产生的温室气体(GHG)上,很少关注农村地区。在此背景下,本研究旨在确定二氧化碳(CO2)的排放源,并估算尼日利亚三角洲州乌杜地方政府因消耗薪材而产生的 CFP 量。研究数据来自从 32 个村庄中随机抽取的四(4)个农村定居点的 200 户家庭。研究采用混合调查技术收集数据,包括问卷调查、实地观察和测量。研究采用描述性统计、皮尔逊相关分析和 CFP 计算方法对获得的数据进行了分析。研究显示,二氧化碳的主要排放源是薪材(82.0%),用于各种家庭和生产活动,每个抽样家庭平均消耗 39.58 千克薪材,因此每天产生 7.24314 公吨的二氧化碳。CFP 的数量也随抽样家庭的规模而直接变化。研究建议开发和利用清洁能源替代资源,以促进环境的可持续发展,缓解气候变化现象。
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引用次数: 0
Antidyslipidemic effect of ethanol extract of Irvingia wombolu seeds in high fat diet induced dyslipidemic rat 翁丁子乙醇提取物对高脂饮食诱导的血脂异常大鼠的降脂作用
Pub Date : 2024-05-14 DOI: 10.4314/sa.v23i2.27
L. Chuku, J. O. Uba, O. E. Ezim
The antidyslipidemic activity of Irvingia wombolu ethanol seeds extract was studied in high fat diet induced dyslipidemic rats.Forty five (45) Wstar rats were grouped into 5 groups of 9 rats each. The animals were allowed 7 days acclimatization period. Group 1 was the control group and it received normal rat chow and water throughout the study. Groups 2 to 5 were given high fat diet for 14 days after which they were given normal rat chow till the end of the study. At the end of the 14 days, group 2 was not treated while group 3-5 were treated with 250, 500 and 1000mg/kg b.w ethanol extract of Irvingia wombolu seeds respectively for 28 days. The lipid  profile of animals was evaluated three times: first after 14 days induction period (phase 1) i.e day 0 of treatment, second was taken 14 days after treatment (phase 2), third was taken 28 days after treatment (phase 3). The study lasted for 49 days and dimethyl sulphoxide was used as a vehicle for the extract. In phase 1, all the groups fed with high fat diet showed an increase in low density lipoprotein (LDL) triglyceride, total cholesterol and a decrease in high density lipoprotein (HDL) levels. In phase 2 there was a decrease in LDL, triglyceride and total cholesterol level in addition to increase in HDL for animals in all the treatment groups. It was observed that in phase 3 only 250mg/kg group showed a progressive decrease in LDL, triglyceride, total cholesterol and an increase in HDL levels while 500 and 1000 mg/kg b.w showed an increase in LDL, triglyceride and total cholesterol level and a decrease in HDL. The result of the present study demonstrated the antidyslipidemic effect  of ethanol extract of Irvingia wombolu seeds at lower dose. 
45 只 Wstar 大鼠被分成 5 组,每组 9 只。将 45 只 Wstar 大鼠分为 5 组,每组 9 只,给予动物 7 天的适应期。第 1 组为对照组,在整个研究期间食用正常的大鼠饲料和水。第 2 至第 5 组给大鼠喂食高脂肪食物 14 天,然后给它们喂食正常的大鼠饲料,直到研究结束。14 天结束时,第 2 组不进行处理,而第 3-5 组则分别用 250、500 和 1000 毫克/千克体重的欧文尼亚翁布鲁种子乙醇提取物处理 28 天。对动物的血脂状况进行了三次评估:第一次是在 14 天的诱导期后(第 1 阶段),即治疗的第 0 天;第二次是在治疗 14 天后(第 2 阶段);第三次是在治疗 28 天后(第 3 阶段)。研究持续了 49 天,二甲基亚砜被用作提取物的载体。在第一阶段,所有以高脂肪饮食喂养的组均显示低密度脂蛋白(LDL)甘油三酯和总胆固醇水平升高,而高密度脂蛋白(HDL)水平下降。在第二阶段,所有处理组动物的低密度脂蛋白、甘油三酯和总胆固醇水平都有所下降,而高密度脂蛋白水平则有所上升。据观察,在第 3 阶段,只有 250 毫克/千克组的低密度脂蛋白、甘油三酯和总胆固醇水平逐渐下降,高密度脂蛋白水平上升,而 500 毫克和 1000 毫克/千克体重组的低密度脂蛋白、甘油三酯和总胆固醇水平上升,高密度脂蛋白水平下降。本研究结果表明,在较低剂量下,欧文花籽乙醇提取物具有降血脂作用。
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引用次数: 0
Comparative morpho-anatomy of two sedges (Cyperus cyperoides(L.) Kuntze and Cyperus rotundus 两种莎草(Cyperus cyperoides(L.)Kuntze和Cyperus rotundus)的形态解剖比较
Pub Date : 2024-05-14 DOI: 10.4314/sa.v23i2.10
C. Wahua, M. Abass
The research investigated the comparative morpho-anatomy of two sedges (Cyperus cyperoides (L.) Kuntze and Cyperus rotundus L.), members of the family Cyperaceae. They are perennial herbs and the former commonly known as commonflat sedge and the latter nut sedge or purple nutsedge. The epidermal peels were obtained by standard methods. The samples were fixed in formaldehyde, glacial acetic acid, 70% alcohol in the ratio of 1:1:18, dehydrated in alcohol solutions of 50%, 70%, 90%, absolute and sectioned, stained in 2% aqueous solution of Safranin O, counter stained in Alcian blue, mounted in glycerine.The result on epidermal studies showcased both kidney and dumbbell-shaped guard cells, graminaceous stomata which is amphistomatic for both species. The anatomical studies revealed scattered vascular bundies in ground tissues of stems, bulliform cells at adaxial foliar organs. The pith sections have large pith and a single row of barrel shaped endodermis prominently pronounced. The research findings here would assist in improving upon already existing knowledge about C. cyperoides and C rotundus. 
这项研究调查了两种莎草(Cyperus cyperoides (L.) Kuntze 和 Cyperus rotundus L.)的形态解剖学比较,它们都属于莎草科。它们都是多年生草本植物,前者通常被称为普通扁平莎草,后者则被称为坚果莎草或紫色坚果草。表皮通过标准方法获得。样品用甲醛、冰醋酸和 70% 的酒精按 1:1:18 的比例固定,在 50% 、70% 、90% 和绝对酒精溶液中脱水并切片,用 2% 的 Safranin O 水溶液染色,用阿尔新蓝反染色,用甘油装裱。解剖学研究显示,茎的基部组织中有分散的维管束,叶面器官的正面有牛皮状细胞。髓部切片的髓较大,单排桶状内皮明显。这些研究结果将有助于提高人们对香蒲和罗汉松的认识。
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引用次数: 0
Detection of syphilis among patients attending a General Hospital in Ogbakiri, River State, Nigeria 在尼日利亚里弗州奥格巴基里一家综合医院就诊的患者中检测梅毒
Pub Date : 2024-05-14 DOI: 10.4314/sa.v23i2.16
Tochi Ifeoma Cookey, D.S. Isheke, M. Elenwo, C. M. Enemchukwu, H. Innocent-Adiele, C. C. Adim, E. N. Onu, A. Awanye, G. A. Nwankwo, M. U. Igwe, I. Okonko
The syphilis-causing agent, Treponema pallidum, has long posed a threat to public health. In sub- Saharan Africa, it is a significant public health issue and is common in developing nations. This study looked into the syphilis prevalence among patients at Rivers State's Ogbakiri General Hospital. Eighty-nine samples were used in total for this investigation after haemolysing; those with fibrin and heavy particles were discarded. For these samples, stratified socio-demographic data were used. In the population, 31 (34.8%) patients were males and 58 (65.2%) were females. Ages ranged from 18 to 75, individuals between the ages of 18 and 30 made up 56.2% of the population; patients between the ages of 31 and 40 made up 10.1% patients between the ages of 41 and 60 made up 21.4% and patients aged 61 and beyond made up 12.4%. Also, 38 (42.7%) and 51 (57.3%) of the population, respectively, were singles and married, 13 (14.6%) of the study population had primary education, 45 (50.6%) had secondary education, and 23 (25.8%) had postsecondary education, according to the results of the educational status analysis. Based on occupational status, there were 8 (8.9%) nurses. According to the study, 2.2% of those who tested were positive for syphilis. Syphilis was found to be more common in people aged 61 to 75 (9.1%), males (3.2%), singles (5.3%) and higher educational status (4.3%). According to this report, Ogbakiri, Nigeria's Rivers State has a relatively low syphilis prevalence compared to other areas in the country. 
长期以来,梅毒致病菌苍白螺旋体一直对公共卫生构成威胁。在撒哈拉以南非洲地区,梅毒是一个重要的公共卫生问题,在发展中国家很常见。本研究调查了河流州奥格巴基里综合医院患者的梅毒患病率。本次调查共使用了 89 份溶血后的样本,其中含有纤维蛋白和重颗粒的样本被弃置。对这些样本采用了分层社会人口学数据。其中,男性患者 31 人(占 34.8%),女性患者 58 人(占 65.2%)。年龄介于 18 岁至 75 岁之间,其中 18 岁至 30 岁的患者占 56.2%;31 岁至 40 岁的患者占 10.1%;41 岁至 60 岁的患者占 21.4%;61 岁及以上的患者占 12.4%。此外,根据教育状况分析的结果,单身和已婚人口分别占 38(42.7%)和 51(57.3%),研究人群中有 13(14.6%)人受过初等教育,45(50.6%)人受过中等教育,23(25.8%)人受过高等教育。根据职业状况,护士有 8 人(8.9%)。研究结果显示,2.2%的检测结果呈梅毒阳性。研究发现,梅毒在61至75岁(9.1%)、男性(3.2%)、单身(5.3%)和教育程度较高(4.3%)的人群中更为常见。根据这份报告,与尼日利亚其他地区相比,尼日利亚河流州奥格巴基里的梅毒发病率相对较低。
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引用次数: 0
Evaluation of the protective activity of aqueous leaf extract of Cissus populnea against lead-induced testicular toxicity in Wistar rats. 评估白千层叶水提取物对铅诱导的 Wistar 大鼠睾丸毒性的保护活性。
Pub Date : 2024-05-14 DOI: 10.4314/sa.v23i2.25
O.U. Idemudia, O.I. Momodu
Cissus populnea, a plant native to West Tropical Africa, has garnered attention, particularly for its use in traditional medicine to improve genital erection in males. Accordingly, this study investigated the possible protective effects of aqueous leaf extract of Cissus populnea (ACPE) against lead acetate-induced testicular toxicity in Wistar rats. Twenty adult Wistar rats were divided into four groups and administered various treatments, including 50mg/kg body weight (BW) of lead acetate, 1000 mg/kg BW of ACPE, or a combination of both, for 28 days via an orogastric tube. Thereafter, animals were sacrificed and various parameters, including body weight changes, sperm quality, and histology of testes were evaluated. Lead acetate exposure led to significant (P<0.05) weight loss, reduction in sperm count and motility as well as histological alterations of the testes. However, ACPE treatment significantly (P<0.05) mitigated the adverse effects induced by lead in the testes of exposed rats. Taken together, these findings underscore the potential of Cissus populnea as a possible protective agent against lead-induced testicular toxicity, thus offering important insights for future treatment options derived from natural sources. 
白千层(Cissus populnea)是一种原产于非洲热带西部的植物,因其在传统医学中用于改善男性生殖器勃起而备受关注。因此,本研究调查了白胡桃叶水提取物(ACPE)对醋酸铅诱导的 Wistar 大鼠睾丸毒性可能产生的保护作用。20 只成年 Wistar 大鼠被分为四组,并通过口胃管连续 28 天接受不同的治疗,包括 50 毫克/千克体重(BW)的醋酸铅、1000 毫克/千克体重(BW)的 ACPE 或两者的组合。之后,动物被处死,并对体重变化、精子质量和睾丸组织学等各种参数进行评估。接触醋酸铅导致动物体重明显下降(P<0.05)、精子数量和活力减少以及睾丸组织学改变。然而,ACPE 治疗能明显(P<0.05)减轻铅对暴露大鼠睾丸的不良影响。综上所述,这些研究结果突出表明了白千层作为一种可能的保护剂来防止铅诱导的睾丸毒性的潜力,从而为未来从天然资源中提取治疗方案提供了重要的启示。
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Scientia Africana
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