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Evaluation of serum resistin levels in Iraqi rheumatoid arthritis patients under biological treatment and their correlated clinical disease activity index 伊拉克类风湿关节炎生物治疗患者血清抵抗素水平及其相关临床疾病活动性指标的评价
Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-23
None Shatha Sabah Shyaa, None Hanaa Naji Abdullah, None Khaled Yassin Zakair
Objective: The current study aimed to evaluate RA patients’ serum resistin levels and to observe the relationshipbetween disease activity and resistin.Methods: A case-control study was conducted on (100) RA Iraqi patients during treatment with bDMARDs. The firstgroup of 50 patients received etanercept, and the second group of 50 patients were on Rituximab (RTX). The controlgroup comprised of 50 healthy individuals. ELISA was used to evaluate serum Resistin in and anti-CRP. Inflammatorymarkers ESR, and CRP with biochemical tests were conducted. In addition to estimating Clinical Disease Activity scoreI(CDAI) by the physicians; at Baghdad Teaching Hospital.Results: Levels of Resistin of RA treated with RTX were significantly higher (16.30 ± 7.38ng/ml) than in RA treated withETN (10.61±5.85ng/ml) compared to the control group. (6.95±1.70 ng/ml). The resistin level showed a positivecorrelation with Anti-CCP abs which was considered to have a high positive correlation (p< 0.01) in ETN group. Whilethis correlation was lower than the RTX group, the, correlation between resistin, and ESR was the highest in RTX groupwhilst no such correlation was observed in the ETN group. There was a positive correlation with CDAI of RA subgroups(moderate activity (p<0.05), and high activity (p<0.001). The logistic regression of resistin was associated with biologicaltreatment, odds ratio was (OR=1.138, p-value= 0.014, 95% CI.1.025-1.257) during ETN, and RTX independent of CRP.Conclusion: There is an association between serum RSN and anti CRP as a result of disease activity independent ofCRP. resist in levels can be used to determine disease activity to avoid disease progression and erosion.Keywords: Protein, Antibodies, Etanercept, Rituximab, Disease, Physicians
目的:本研究旨在评估RA患者血清抵抗素水平,并观察疾病活动度与抵抗素的关系。方法:对100例伊拉克类风湿性关节炎患者进行bDMARDs治疗的病例对照研究。第一组50例患者使用依那西普,第二组50例患者使用利妥昔单抗(RTX)。对照组由50名健康个体组成。ELISA法检测血清抵抗素和抗crp。进行炎症标志物ESR、CRP及生化检测。除了由医生估计临床疾病活动评分(CDAI)外;在巴格达教学医院结果:RTX组RA抵抗素水平(16.30±7.38ng/ml)明显高于thetn组(10.61±5.85ng/ml)。(6.95±1.70 ng / ml)。抵抗素水平与抗ccp抗体呈正相关,被认为具有高度正相关(p<ETN组为0.01)。虽然这种相关性低于RTX组,但抵抗素与ESR之间的相关性在RTX组中最高,而在ETN组中未观察到这种相关性。与RA亚组CDAI呈正相关(中度活动(p<0.05),高活性(p<0.001)。在ETN期间,抵抗素的logistic回归与生物治疗相关,优势比为(OR=1.138, p值= 0.014,95% CI.1.025-1.257), RTX与CRP无关。结论:血清RSN与抗CRP之间存在相关性,这是独立于CRP的疾病活动性的结果。抵抗水平可用于确定疾病活动,以避免疾病进展和侵蚀。关键词:蛋白质,抗体,依那西普,利妥昔单抗,疾病,医生
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引用次数: 0
The effectiveness of eucalyptus globulus and thymus vulgaris in reducing COVID-19 symptoms among COVID-19 patients at Al- Nasiriya City 巨桉和寻常胸腺对减轻纳西里耶市COVID-19患者症状的效果
Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-16
None Rawaa Kamel Abd, None Duaa Abd Al Azem, None Ayad Abbas Aend, None Khalied Yassen Zakair
Objective: To determine how Thymus vulgaris and Ecalyptus globulus affected the symptoms of coronavirus disease-2019 patients.Method: The experimental case-control study was conducted in Al-Nasiriya city, Iraq, from December 15, 2020, toFebruary 20, 2021, and comprised patients of either gender aged 20-50 years diagnosed with coronavirus disease-2019 infection. The patients’ symptoms ranged from mild to severe. Half of the sample was exposed to the study’streatment protocol, while the other half acted as control. Thyme, orange and lemon were employed as sources ofvitamin C, as well as eucalyptus leaves and oil. The cases were exposed to eucalyptus vapours for 5-10 minutes afterthoroughly washing the plant leaves (7-10 leaves or 5 drops of oil) and boiling them in drinking water at 100°C for 10-15 minutes. Data was analysed using SPSS 23.Results: Of the 48 patients, 24(50%) were in each of the two groups. Age and gender were not significantly different(p>0.05), while body mass index and blood group distribution was significantly different between the groups (p<0.05).Overall, 22(45.8%) subjects had mild symptoms, 20(41.7%) had moderate symptoms and 6(12.5%) had severesymptoms. The improvement in the symptoms among the cases was significantly more than the controls (p<0.05)except nasal congestion (p>0.05).Conclusion: Using eucalyptus vapours in the form of dried leaves or oil could significantly lessen coronavirus disease-2019 symptoms.Keywords: Eucalyptus, Thymus, Plant, Citrus, Cough, Smell, COVID-19, Leaves, Vaccines, Vitamins.
目的:探讨寻常胸腺和巨桉对冠状病毒病(2019)患者症状的影响。方法:于2020年12月15日至2021年2月20日在伊拉克Al-Nasiriya市开展实验性病例对照研究,纳入年龄在20-50岁之间的诊断为冠状病毒病-2019感染的患者。患者的症状从轻微到严重不等。一半的样本暴露在研究的治疗方案中,而另一半作为对照。百里香、橙子和柠檬被用作维生素C的来源,桉树叶和油也被用作维生素C的来源。在彻底清洗植物叶片(7-10片叶子或5滴油)并在100°C的饮用水中煮沸10-15分钟后,将病例暴露于桉树蒸气中5-10分钟。数据采用SPSS 23进行分析。结果:48例患者中,两组各24例(50%)。年龄、性别差异无统计学意义(p>0.05),体重指数、血型分布差异有统计学意义(p>0.05)。总体而言,轻度症状22例(45.8%),中度症状20例(41.7%),重度症状6例(12.5%)。除鼻塞(p>0.05)外,各病例症状改善程度均显著高于对照组(p>0.05)。结论:使用干叶或油形式的桉树蒸气可以显着减轻2019冠状病毒病的症状。关键词:桉树、胸腺、植物、柑橘、咳嗽、气味、COVID-19、叶子、疫苗、维生素。
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引用次数: 0
Red eyes: COVID-19 or Microbial infection 眼睛发红:COVID-19或微生物感染
Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-10
None Hussein Katai Abdul Sada, None Salah Zuhair Abed Al Asadi, None Ahmed Mohammed Alsamak, None Amaleed Abduljaleel Alkadhem
Objective: To identify the source of eyes infections during coronavirus disease-2019 pandemic.Method: The cross-sectional study was conducted at the Al-Basrah Teaching Hospital, Iraq from March 2 to September24, 2020, and comprised eye swabs from patients having confirmed diagnosis of coronavirus disease-2019. The swabswere subjected to microbiological and molecular examinations. They were cultivated on blood agar and savoureddextrose agar plates to detect the types of microbes and then confirmed by genetic analysis using polymerase chainreaction. Chi-square was used to identify the differences between samples who had symptoms or those who had nosymptoms p Less than or Equal to 0.05 was considered significant.Results: Of the 213 patients quarantined with coronavirus disease-2019, there were 98(46%) males and 115(54%)females. Of them, 22(10.3%) had red eyes; 10(45.45%) males and 12(54.54%) females, with overall age ranging 18-74years. Streptococcus pneumonia was detected in 8(36.6%) patients, followed by staphylococcus aureus and candidaalbicans 5(22.7%) each, and haemophilus influenzae 3(13.6%).Conclusion: Red eyes of some patients with coronavirus disease-2019 may have been caused by secondary infection.Keywords: Agar, Staphylococcus aureus, Photophobia, Polymerase chain reaction, Glucose, Pruritus.
目的:确定2019冠状病毒病大流行期间眼部感染的来源。方法:于2020年3月2日至9月24日在伊拉克巴士拉教学医院进行横断面研究,收集确诊为2019冠状病毒病的患者的眼拭子。拭子进行微生物和分子检查。分别在血琼脂和品味葡萄糖琼脂上培养,检测微生物类型,然后用聚合酶链反应进行遗传分析。使用卡方来确定有症状或无症状的样本之间的差异p小于或等于0.05被认为是显著的。结果:213例新冠肺炎隔离患者中,男性98例(46%),女性115例(54%)。其中22例(10.3%)出现红眼;男性10例(45.45%),女性12例(54.54%),总体年龄18 ~ 74岁。检出肺炎链球菌8例(36.6%),其次是金黄色葡萄球菌5例(22.7%),白色念珠菌5例(22.7%),流感嗜血杆菌3例(13.6%)。结论:部分冠状病毒病-2019患者出现红眼可能是继发感染所致。关键词:琼脂,金黄色葡萄球菌,畏光,聚合酶链反应,葡萄糖,瘙痒症
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引用次数: 0
Correlation between Neutrophil gelatinase-associated lipocalin and ß2-Microglobulin with serum protein electrophoresis in multiple myeloma patients 多发性骨髓瘤患者中性粒细胞明胶酶相关脂钙蛋白和ß - 2微球蛋白与血清蛋白电泳的相关性
Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-01
None Inas Nazeeh Abed, None Hiba Abid Al-Hussein Hassan, None Usama Salman Al Timari
Objective: To find the correlation between neutrophil gelatinase-associated lipocalin and beta2-microglobulin inpatients with multiple myeloma.Method: The case-control study was conducted from November 2021 to March 2022, after approval from ethics reviewcommittees of three major medical establishments in Baghdad, Iraq. There were randomly selected multiple myelomapatients of either gender with normal concentration of urea and creatinine in group A, multiple myeloma patients ofeither gender with increased concentration of urea and creatinine in group B and healthy controls in group C.Neutrophil gelatinase-associated lipocalin and beta2-microglobulin were assessed using enzyme-linkedimmunosorbent assay technique. Data was analysed using SPSS 26.Results: Of the 180 subjects, there were 60(33.3%) in each of the 3 groups, with each group having 40(66.5%) malesand 20(33.3%) females, and overall age ranging 40-79 years. Protein electrophoresis in group A patients wassignificantly higher (p=0.001) in alpha1, beta and gamma globulin. Among group B patients, a highly significantincrease (p=0.001) was noted in alpha1, alpha2, beta and gamma globulin. Beta2-microglobulin was a more sensitiveand specific marker for renal injury than neutrophil gelatinase-associated lipocalin in myeloma patients(p<0.05).Conclusion: Beta2-microglobulin and neutrophil gelatinase-associated lipocalin were both more sensitive markersthan serum urea and creatinine in the diagnosis of acute kidney injury in multiple myeloma patients.Keywords: Lipocalin, Creatinine, Multiple myeloma, Microglobulin, Urea, Electrophoresis, Globulins, Albumins,Enzyme, Immunosorbent assay, Kidney injury.
目的:探讨多发性骨髓瘤患者中性粒细胞明胶酶相关脂钙素与β 2微球蛋白的相关性。方法:经伊拉克巴格达三家主要医疗机构伦理审查委员会批准,于2021年11月至2022年3月进行病例对照研究。随机选择尿素和肌酐浓度正常的多发性骨髓瘤患者(A组),尿素和肌酐浓度升高的多发性骨髓瘤患者(B组)和健康对照(c组),采用酶联免疫吸附法检测中性粒细胞明胶酶相关脂钙蛋白和β 2微球蛋白。数据采用SPSS 26进行分析。结果:180例受试者中,3组各有60例(33.3%),其中每组男性40例(66.5%),女性20例(33.3%),总体年龄40 ~ 79岁。A组患者α 1、β和γ球蛋白蛋白电泳显著升高(p=0.001)。在B组患者中,α 1、α 2、β和γ球蛋白显著升高(p=0.001)。在骨髓瘤患者中,β 2-微球蛋白比中性粒细胞明胶酶相关脂钙蛋白更敏感、更特异(p < 0.05)。结论:β -微球蛋白和中性粒细胞明胶酶相关脂钙素在多发性骨髓瘤患者急性肾损伤诊断中的敏感性均高于血清尿素和肌酐。关键词:脂载蛋白,肌酐,多发性骨髓瘤,微球蛋白,尿素,电泳,球蛋白,白蛋白,酶,免疫吸附试验,肾损伤。
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引用次数: 0
The effect of letrozole treatment on the fertility and embryos parameters in female mice: Histological and hormonal study 来曲唑对雌性小鼠生育能力和胚胎参数的影响:组织学和激素研究
Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-31
None Sally Adnan Mousa AL Rekabi, None Noor Noori Abid Al Shemary
Objective: To evaluate how letrozole affects reproductive hormones and embryos in mature female mice.Method: The investigative study was conducted from December 2021 to February 2022 at the Pathology Departmentof Kut Technical Institute, Al-Kut, Iraq, and comprised adult female albino mice weighing 23-25g. The mice were dividedinto control group A, those receiving 1.5mg/kg/day letrozole in group B, and those receiving 2.5mg/kg/day letrozolein group C. The intervention lasted 14 days. Blood samples were collected under anaesthesia by heart puncture forhormonal testing. Data was analysed using SPSS 15.Results: Of the 30 mice, 10(33.3%) were in each of the 3 groups. Right and left ovaries of mice in groups B and Cshowed a significant rise in multi-follicular cells compared to group A (p<0.05). Follicle-stimulating hormone, oestrogenand progesterone concentrations as well as luteinizing hormone increased significantly in the intervention groupscompared to the control group (p<0.05). The impact of letrozole on embryos was significant in groups B and Ccompared to group A.Conclusions: Letrozole was found to have a positive effect on reproductive parameters and hormones in mice.Keywords: Mice, Ovary, Letrozole, oestrogen, Progesterone, Luteinizing hormone.
目的:探讨来曲唑对成熟雌鼠生殖激素及胚胎的影响。方法:调查研究于2021年12月至2022年2月在伊拉克Al-Kut技术研究所病理学系进行,选取体重23-25g的成年雌性白化小鼠。将小鼠分为对照组A、来曲唑1.5mg/kg/d组B、来曲唑2.5mg/kg/d组c,干预14 d。麻醉下取血穿刺进行激素检测。数据采用SPSS 15进行分析。结果:30只小鼠中,3组各10只(33.3%)。B组和c组小鼠左右卵巢多滤泡细胞较a组显著增加(p < 0.05)。干预组促卵泡激素、雌激素、孕酮浓度及黄体生成素均较对照组显著升高(p < 0.05)。与a组相比,B组和c组来曲唑对胚胎的影响显著。结论:来曲唑对小鼠生殖参数和激素有积极影响。关键词:小鼠,卵巢,来曲唑,雌激素,黄体酮,黄体生成素
{"title":"The effect of letrozole treatment on the fertility and embryos parameters in female mice: Histological and hormonal study","authors":"None Sally Adnan Mousa AL Rekabi, None Noor Noori Abid Al Shemary","doi":"10.47391/jpma.iq-31","DOIUrl":"https://doi.org/10.47391/jpma.iq-31","url":null,"abstract":"Objective: To evaluate how letrozole affects reproductive hormones and embryos in mature female mice.Method: The investigative study was conducted from December 2021 to February 2022 at the Pathology Departmentof Kut Technical Institute, Al-Kut, Iraq, and comprised adult female albino mice weighing 23-25g. The mice were dividedinto control group A, those receiving 1.5mg/kg/day letrozole in group B, and those receiving 2.5mg/kg/day letrozolein group C. The intervention lasted 14 days. Blood samples were collected under anaesthesia by heart puncture forhormonal testing. Data was analysed using SPSS 15.Results: Of the 30 mice, 10(33.3%) were in each of the 3 groups. Right and left ovaries of mice in groups B and Cshowed a significant rise in multi-follicular cells compared to group A (p<0.05). Follicle-stimulating hormone, oestrogenand progesterone concentrations as well as luteinizing hormone increased significantly in the intervention groupscompared to the control group (p<0.05). The impact of letrozole on embryos was significant in groups B and Ccompared to group A.Conclusions: Letrozole was found to have a positive effect on reproductive parameters and hormones in mice.Keywords: Mice, Ovary, Letrozole, oestrogen, Progesterone, Luteinizing hormone.","PeriodicalId":16673,"journal":{"name":"Journal of Pakistan Medical Association","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134944096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sero-prevalence of Hepatitis C virus infection in patients undergoing haemodialysis in Al-Najaf Province 纳杰夫省血液透析患者丙型肝炎病毒感染的血清流行率
Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-34
None Khalida Abbas Al Kelaby, None Qabas Neamah Hadi Al Hajjar, None Ghaith Kadhim Al Azam
This study identified the predominance of HCV in patients undergoing haemodialysis and the risk factors related to age, gender, residence and occupation. It was conducted in the haemodialysis centre in Al-Saddar hospital in Al-Najaf province. A total of 193 patients were enrolled. Blood was drawn for testing HCV antibodies using ELISA. A positive result for presence of antibodies confirmed HCV infection. Of 193 patients studied, 43(22.3%) were infected with HCV. The higher frequency of infection was in the age group 31- 50 years (11.4%). The rate of HCV in women was (22.89%), while in men it was (21.81%) which was an insignificant difference. Continue....
本研究确定了HCV在血液透析患者中的优势,以及与年龄、性别、居住地和职业相关的危险因素。它是在纳杰夫省Al-Saddar医院的血液透析中心进行的。共有193名患者入组。采用ELISA法抽血检测HCV抗体。抗体阳性结果证实HCV感染。在研究的193例患者中,43例(22.3%)感染HCV。31 ~ 50岁年龄组感染率最高(11.4%)。HCV检出率女性为22.89%,男性为21.81%,差异无统计学意义。继续……
{"title":"Sero-prevalence of Hepatitis C virus infection in patients undergoing haemodialysis in Al-Najaf Province","authors":"None Khalida Abbas Al Kelaby, None Qabas Neamah Hadi Al Hajjar, None Ghaith Kadhim Al Azam","doi":"10.47391/jpma.iq-34","DOIUrl":"https://doi.org/10.47391/jpma.iq-34","url":null,"abstract":"This study identified the predominance of HCV in patients undergoing haemodialysis and the risk factors related to age, gender, residence and occupation. It was conducted in the haemodialysis centre in Al-Saddar hospital in Al-Najaf province. A total of 193 patients were enrolled. Blood was drawn for testing HCV antibodies using ELISA. A positive result for presence of antibodies confirmed HCV infection. Of 193 patients studied, 43(22.3%) were infected with HCV. The higher frequency of infection was in the age group 31- 50 years (11.4%). The rate of HCV in women was (22.89%), while in men it was (21.81%) which was an insignificant difference. Continue....","PeriodicalId":16673,"journal":{"name":"Journal of Pakistan Medical Association","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134944210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Workplace stress among healthcare workers in Kut city, Iraq, 2020 2020年,伊拉克库特市医护人员的工作压力
Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-09
None Fatima Haran Deham, None Alaa Kadhim Jasim, None Khalied Yassen Zakair
Objective: To identify workplace stress in healthcare workers.Method: The cross-sectional, descriptive study was conducted at Al-Kut and Al-Karamah hospitals in Kut,Iraq, from October 2019 to March 2020, and comprised health professionals regardless of age and gender.Data was collected through a pilot-tested questionnaire which was validated by a panel of experts. Datawas analysed using SPSS 25.Results: Of the 266 subjects, 133(50%) were from each of the two hospitals. Overall, there were 156(58.6%)females and 110(41.4%) males. There were 195(73.3%) subjects aged <30 years, 40(15%) aged 31-40 yearsand 31(11.7%) aged >40 years (p=0.625). There were 19(7.1%) physicians 72(27.1%) nurses, 88(33.1%)technicians and 87(32.7%) other healthcare workers. Stress was found in 20(7.5%) subjects; 13(65%) inAl-Karamah Hospital and 7(35%) in Al-Kut Hospital (p=0.245).Conclusion: The prevalence of stress was low among the health workers studied.Keywords: Stress, Ergonomics, Healthcare, Workers, Workplace.
目的:了解卫生保健工作者的工作压力。方法:横断面描述性研究于2019年10月至2020年3月在伊拉克库特的Al-Kut和Al-Karamah医院进行,包括不分年龄和性别的卫生专业人员。数据是通过一份经过试点测试的问卷收集的,该问卷由一个专家小组验证。数据采用SPSS 25进行分析。结果:266例患者中,两家医院各133例(50%)。女性156人(58.6%),男性110人(41.4%)。30岁195例(73.3%),31-40岁40例(15%),40岁31例(11.7%)(p=0.625)。其中医生19人(7.1%),护士72人(27.1%),技术人员88人(33.1%),其他卫生保健工作者87人(32.7%)。20例(7.5%)出现应激;13人(65%)在卡拉马医院,7人(35%)在库特医院(p=0.245)。结论:被调查医务人员的压力患病率较低。关键词:压力,人体工程学,医疗保健,工人,工作场所。
{"title":"Workplace stress among healthcare workers in Kut city, Iraq, 2020","authors":"None Fatima Haran Deham, None Alaa Kadhim Jasim, None Khalied Yassen Zakair","doi":"10.47391/jpma.iq-09","DOIUrl":"https://doi.org/10.47391/jpma.iq-09","url":null,"abstract":"Objective: To identify workplace stress in healthcare workers.Method: The cross-sectional, descriptive study was conducted at Al-Kut and Al-Karamah hospitals in Kut,Iraq, from October 2019 to March 2020, and comprised health professionals regardless of age and gender.Data was collected through a pilot-tested questionnaire which was validated by a panel of experts. Datawas analysed using SPSS 25.Results: Of the 266 subjects, 133(50%) were from each of the two hospitals. Overall, there were 156(58.6%)females and 110(41.4%) males. There were 195(73.3%) subjects aged <30 years, 40(15%) aged 31-40 yearsand 31(11.7%) aged >40 years (p=0.625). There were 19(7.1%) physicians 72(27.1%) nurses, 88(33.1%)technicians and 87(32.7%) other healthcare workers. Stress was found in 20(7.5%) subjects; 13(65%) inAl-Karamah Hospital and 7(35%) in Al-Kut Hospital (p=0.245).Conclusion: The prevalence of stress was low among the health workers studied.Keywords: Stress, Ergonomics, Healthcare, Workers, Workplace.","PeriodicalId":16673,"journal":{"name":"Journal of Pakistan Medical Association","volume":"130 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134944345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between social support and self-hardiness among breast cancer women in Nasiriyah, Iraq 伊拉克纳西里耶乳腺癌妇女的社会支持与自我适应能力的关系
Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-02
None Gossoon Juma Elywy, None Mohammed Malih Radhi, None Qasim Abbas Khyoosh AlEqabi
Objective: To assess the role of social support in predicting self-hardiness among women having breast cancer.Method: The descriptive correlational study was conducted at the Oncology Centre, Nasiriyah, Iraq, from August 3 toSeptember 22, 2022, and comprised women receiving treatment for breast cancer. Data was collected using a questionnairedesigned in the light of the Multidimensional Scale of Perceived Social Support, which was found reliable on the basis of apilot study. Data was analysed using SPSS 20.Results: There were 150 women with mean age 50.4±11.18 years. Of them, 135(90%) were married, 113(75.3%) wereunemployed, 90(60%) were living in rural areas, and 89(59.3%) had low socioeconomic status. Overall, 108(72%) patientsreported they received little social support. Self-hardiness significantly differed in relation to marital status (p=0.021), placeof residence (p=0.003) and income level (p=0.005). Social support positively correlated with self-hardiness (p=0 .000).Conclusion: Social support was found to be a predictor of increased self-hardiness that enhances resilience and enablespatients to deal with one of the most devastating illnesses of modern times.Keywords: Cancer, Breast, Neoplasms, Counselling.
目的:探讨社会支持对乳腺癌患者自我适应力的预测作用。方法:描述性相关研究于2022年8月3日至9月22日在伊拉克纳西里耶肿瘤中心进行,包括接受乳腺癌治疗的妇女。数据的收集采用了一份根据感知社会支持多维度量表重新设计的问卷,在初步研究的基础上发现该问卷是可靠的。数据采用SPSS 20进行分析。结果:患者150例,平均年龄50.4±11.18岁。其中,已婚135人(90%),无业113人(75.3%),农村90人(60%),社会经济地位低89人(59.3%)。总体而言,108名(72%)患者报告说他们很少得到社会支持。自我耐寒性与婚姻状况(p=0.021)、居住地(p=0.003)和收入水平(p=0.005)有显著差异。社会支持与自我适应力呈正相关(p= 0.000)。结论:研究发现,社会支持可以预测自我适应力的增强,从而增强患者的复原力,使他们能够应对现代最具破坏性的疾病之一。关键词:癌症,乳腺癌,肿瘤,咨询
{"title":"Relationship between social support and self-hardiness among breast cancer women in Nasiriyah, Iraq","authors":"None Gossoon Juma Elywy, None Mohammed Malih Radhi, None Qasim Abbas Khyoosh AlEqabi","doi":"10.47391/jpma.iq-02","DOIUrl":"https://doi.org/10.47391/jpma.iq-02","url":null,"abstract":"Objective: To assess the role of social support in predicting self-hardiness among women having breast cancer.Method: The descriptive correlational study was conducted at the Oncology Centre, Nasiriyah, Iraq, from August 3 toSeptember 22, 2022, and comprised women receiving treatment for breast cancer. Data was collected using a questionnairedesigned in the light of the Multidimensional Scale of Perceived Social Support, which was found reliable on the basis of apilot study. Data was analysed using SPSS 20.Results: There were 150 women with mean age 50.4±11.18 years. Of them, 135(90%) were married, 113(75.3%) wereunemployed, 90(60%) were living in rural areas, and 89(59.3%) had low socioeconomic status. Overall, 108(72%) patientsreported they received little social support. Self-hardiness significantly differed in relation to marital status (p=0.021), placeof residence (p=0.003) and income level (p=0.005). Social support positively correlated with self-hardiness (p=0 .000).Conclusion: Social support was found to be a predictor of increased self-hardiness that enhances resilience and enablespatients to deal with one of the most devastating illnesses of modern times.Keywords: Cancer, Breast, Neoplasms, Counselling.","PeriodicalId":16673,"journal":{"name":"Journal of Pakistan Medical Association","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134943844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular detection of virulence genes in pseudomonas aeruginosa isolated from different clinical infections 不同临床感染源铜绿假单胞菌毒力基因的分子检测
Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-13
None Enass Abdul Kadhum Almkhadhree, None Kawther Adnan Alqaseer, None Khairi Jameel AL Ruaby
Objective: To isolate pseudomonas aeruginosa from different clinical specimens, and to detect virulence factors.Method: The cross-sectional study was conducted at Al-Zharr Hospital and private clinics in Kut city of Wasit provincein Iraq from October 15, 2021, to April 30, 2022, and comprised samples obtained from different patient sites, such aswound swabs, ear swabs, urine samples, burn swabs and respiratory tract swabs. The samples were subjected tomolecular testing using, among other tools, polymerase chain reaction. The isolates were cultured on different media,such as blood agar, MacConkey agar and cetrimide agar, and were further diagnosed by biochemical testing. Datawas analysed using SPSS 20.Results:Of the 212 samples, there were 70(33%) wound swabs, 53(25%) ear swabs, 41(19.3%) urine samples, 33(15.6%)burn swabs and 15(7%) respiratory tract swabs. Pseudomonas aeruginosa was identified in 54(25.47%) isolates viaculture-based characterisation. All 54(100%) isolates were positive for mexR and toxA on polymerase chain reaction,44(81.48%) were positive for exoU gene, 43(79.62%) for exoT gene, 36 (66.66) for exoT gen, 35(64.81%) for plcH, geneand 14(25.92 %) for exoS gene.Conclusions: Wound swabs were found to be the most common site for pseudomonas aeruginosa, followed by earswabs and urine samples.Keywords: Pseudomonas aeruginosa, Virulence, Agar, Cetrimonium, Virulence, Burns, Polymerase chain reaction, DNA.
目的:从不同临床标本中分离铜绿假单胞菌,并对其毒力因素进行检测。方法:横断面研究于2021年10月15日至2022年4月30日在伊拉克瓦西特省库特市的Al-Zharr医院和私人诊所进行,包括从不同患者部位获得的样本,如伤口拭子、耳拭子、尿液样本、烧伤拭子和呼吸道拭子。使用聚合酶链反应等工具对样品进行分子检测。分别在血琼脂、MacConkey琼脂和cetrimide琼脂培养基上进行培养,并进行生化检测。数据采用SPSS 20进行分析。结果:212份样本中,伤口拭子70份(33%),耳拭子53份(25%),尿样41份(19.3%),烧伤拭子33份(15.6%),呼吸道拭子15份(7%)。铜绿假单胞菌54株(25.47%)经培养鉴定。聚合酶链反应54株(100%)mexR和toxA阳性,其中exoU基因阳性44株(81.48%),exoT基因阳性43株(79.62%),exoT基因阳性36株(66.66%),plcH基因阳性35株(64.81%),exoS基因阳性14株(25.92%)。结论:伤口拭子是铜绿假单胞菌最常见的感染部位,其次是耳拭子和尿液。关键词:铜绿假单胞菌,毒力,琼脂,西曲铵,毒力,烧伤,聚合酶链反应,DNA
{"title":"Molecular detection of virulence genes in pseudomonas aeruginosa isolated from different clinical infections","authors":"None Enass Abdul Kadhum Almkhadhree, None Kawther Adnan Alqaseer, None Khairi Jameel AL Ruaby","doi":"10.47391/jpma.iq-13","DOIUrl":"https://doi.org/10.47391/jpma.iq-13","url":null,"abstract":"Objective: To isolate pseudomonas aeruginosa from different clinical specimens, and to detect virulence factors.Method: The cross-sectional study was conducted at Al-Zharr Hospital and private clinics in Kut city of Wasit provincein Iraq from October 15, 2021, to April 30, 2022, and comprised samples obtained from different patient sites, such aswound swabs, ear swabs, urine samples, burn swabs and respiratory tract swabs. The samples were subjected tomolecular testing using, among other tools, polymerase chain reaction. The isolates were cultured on different media,such as blood agar, MacConkey agar and cetrimide agar, and were further diagnosed by biochemical testing. Datawas analysed using SPSS 20.Results:Of the 212 samples, there were 70(33%) wound swabs, 53(25%) ear swabs, 41(19.3%) urine samples, 33(15.6%)burn swabs and 15(7%) respiratory tract swabs. Pseudomonas aeruginosa was identified in 54(25.47%) isolates viaculture-based characterisation. All 54(100%) isolates were positive for mexR and toxA on polymerase chain reaction,44(81.48%) were positive for exoU gene, 43(79.62%) for exoT gene, 36 (66.66) for exoT gen, 35(64.81%) for plcH, geneand 14(25.92 %) for exoS gene.Conclusions: Wound swabs were found to be the most common site for pseudomonas aeruginosa, followed by earswabs and urine samples.Keywords: Pseudomonas aeruginosa, Virulence, Agar, Cetrimonium, Virulence, Burns, Polymerase chain reaction, DNA.","PeriodicalId":16673,"journal":{"name":"Journal of Pakistan Medical Association","volume":"159 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134944351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge, attitude and practice of nursing staff regarding hepatitis B at Kut city, middle Iraq 伊拉克中部库特市护理人员对乙型肝炎的知识、态度和做法
Pub Date : 2023-10-06 DOI: 10.47391/jpma.iq-33
None Rawaa Kamel Abd, None Basim Rihan Sahar
Objective: To assess the level of knowledge, attitude and practice of nursing staff towards hepatitis B virus infection.Method: The cross-sectional study was conducted at three hospitals in Kut, Iraq, in July 2020, and comprised nursingstaff regardless of age and gender. Data was collected using a predesigned questionnaire exploring demographicdetails as well as knowledge, attitude and practice of the nursing staff regarding hepatitis B virus infection. Data wasanalysed using SPSS 21.Result: Of the 3,008 nurses, 341(11.33%) were randomly enrolled; 170(49.9%) males and 171(50.1%) females. Therewere 140(41.1%) subjects aged 20–30 years, while 16(4.7%) were aged Greater than or Equal to 50 years. The mean knowledge score was 22.22±2.79 (range: 18-35 years), indicating better knowledge. The mean attitude score was 19.23±2.74 (range: 11-26), indicating positive attitude. The mean practice score was 13.04±1.84 (range: 8-17) indicating good practices.Conclusion: The knowledge level related to hepatitis B virus among the nursing staff was good. Overall improvementrelated to knowledge, attitude and practice among the nursing staff was needed.Keywords: Hepatitis, Virus, Health, Studies, Nurses, Surveys.
目的:了解护理人员对乙型肝炎病毒感染的知识、态度和行为。方法:横断面研究于2020年7月在伊拉克库特的三家医院进行,包括护理人员,不分年龄和性别。采用预先设计的调查问卷收集数据,调查人口统计细节以及护理人员对乙型肝炎病毒感染的知识、态度和行为。数据采用SPSS 21进行分析。结果:3008名护士中,随机入组341名(11.33%);男性170人(49.9%),女性171人(50.1%)。其中年龄在20 ~ 30岁的140例(41.1%),年龄≥50岁的16例(4.7%)。平均知识得分为22.22±2.79(范围:18-35岁),表明知识水平较好。平均态度得分为19.23±2.74(范围:11-26),为积极态度。练习平均得分为13.04±1.84分(范围:8-17分),表现良好。结论:护理人员对乙型肝炎病毒相关知识的了解程度较好。护理人员的知识、态度和行为等方面有待全面改善。关键词:肝炎,病毒,健康,研究,护士,调查
{"title":"Knowledge, attitude and practice of nursing staff regarding hepatitis B at Kut city, middle Iraq","authors":"None Rawaa Kamel Abd, None Basim Rihan Sahar","doi":"10.47391/jpma.iq-33","DOIUrl":"https://doi.org/10.47391/jpma.iq-33","url":null,"abstract":"Objective: To assess the level of knowledge, attitude and practice of nursing staff towards hepatitis B virus infection.Method: The cross-sectional study was conducted at three hospitals in Kut, Iraq, in July 2020, and comprised nursingstaff regardless of age and gender. Data was collected using a predesigned questionnaire exploring demographicdetails as well as knowledge, attitude and practice of the nursing staff regarding hepatitis B virus infection. Data wasanalysed using SPSS 21.Result: Of the 3,008 nurses, 341(11.33%) were randomly enrolled; 170(49.9%) males and 171(50.1%) females. Therewere 140(41.1%) subjects aged 20–30 years, while 16(4.7%) were aged Greater than or Equal to 50 years. The mean knowledge score was 22.22±2.79 (range: 18-35 years), indicating better knowledge. The mean attitude score was 19.23±2.74 (range: 11-26), indicating positive attitude. The mean practice score was 13.04±1.84 (range: 8-17) indicating good practices.Conclusion: The knowledge level related to hepatitis B virus among the nursing staff was good. Overall improvementrelated to knowledge, attitude and practice among the nursing staff was needed.Keywords: Hepatitis, Virus, Health, Studies, Nurses, Surveys.","PeriodicalId":16673,"journal":{"name":"Journal of Pakistan Medical Association","volume":"300 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134944509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Pakistan Medical Association
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