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Moderating effects of trustworthiness between pharmacists and physicians: using partial least squares 药剂师和医生之间可信度的调节效应:使用偏最小二乘法
IF 0.7 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2021-10-19 DOI: 10.1093/jphsr/rmab048
M. A. Murshid, Z. Mohaidin, Mohammad Zayed, Mohammed A. Al Doghan
Trustworthiness (TRS) is an essential factor that drives pharmacist–physician collaboration (PPC), which, in turn, improves prescribing behaviour. This study examines the moderating effect of TRS on the relationship between pharmacist expertise, PPC and prescribing decisions of physicians (PPD). A total of 393 usable data were collected from selected physicians using a structured questionnaire form. Partial least squares structural equation modelling was adopted for data analysis. The result shows that TRS does not moderate the relationship between pharmacist expertise power and PPD, although the relationship is stronger with higher TRS (β = 0.054, t = 0.483, P > 0.05). As expected, the relationship between PPC and PPD is stronger at high TRS (β = 0.137, t = 1.653, P < 0.05). TRS plays a ‘dynamic’ role in strengthening the positive impact of high pharmacist collaboration on prescribing rather than a ‘supportive’ role in increasing physicians’ readiness to gather information and recommendations from the pharmacist.
可信度(TRS)是推动药剂师与医生合作(PPC)的一个重要因素,这反过来又改善了处方行为。本研究考察了TRS对药剂师专业知识、PPC和医生处方决策(PPD)之间关系的调节作用。采用结构化问卷形式,从选定的医生那里收集了393份可用数据。数据分析采用偏最小二乘结构方程模型。结果表明,TRS并不调节药剂师专业能力与PPD之间的关系,尽管TRS越高,这种关系越强(β=0.054,t=0.483,P>0.05),在高TRS时,PPC和PPD之间的关系更强(β=0.137,t=1.653,P<0.05)。TRS在加强药剂师高度合作对处方的积极影响方面发挥着“动态”作用,而不是在提高医生收集药剂师信息和建议的准备程度方面发挥“支持”作用。
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引用次数: 1
Strategies to decrease COVID-19 vaccine hesitancy for children 减少儿童对新冠肺炎疫苗犹豫的策略
IF 0.7 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2021-10-19 DOI: 10.1093/jphsr/rmab060
M. Zakeri, Jieni Li, Simin D Sadeghi, E. Essien, S. Sansgiry
Abstract Objectives This study aims to understand acceptable strategies to enhance the COVID-19 vaccine uptake among mothers who have no intention to vaccinate their children. Methods In a cross-sectional study, using an online survey in March 2021, we evaluated the variables within the Health Belief Model (severity, susceptibility, benefits, barriers and cues to action) along with parents’ sociodemographic characteristics, previous COVID-19 infection, job loss due to COVID-19 pandemic and the presence of healthcare workers among the household. Total number of children in the household and their chronic health conditions were also assessed. Multivariable logistic regression was performed to evaluate the intention to vaccinate children against the COVID-19 and associations with other variables. Key findings The survey response rate was 32.30% (595/1842). Most of the participants were White (72.1%), 31–40 years old (55.46%) and married or in a cohabiting relationship (90.25). Out of 595 mothers with 3–15 years old children, 38.32% had no intention to vaccinate their children. Top factors associated with intention were perceived susceptibility (P = 0.002), benefits (P < 0.001), barriers (P < 0.001), cues to action (P < 0.001) and the presence of healthcare workers in the household (P = 0.032). The main barriers were concerns about vaccine safety, efficacy and side effects. The strongest cue to action was enough information being provided followed by doctors’ recommendations. Conclusions Strategies to increase vaccination for children lie in the process of convincing parents with providing reliable information on the vaccine safety, efficacy and side effects by paediatricians and other healthcare providers.
摘要目的本研究旨在了解在无意为子女接种新冠肺炎疫苗的母亲中提高疫苗接种率的可接受策略。方法在一项横断面研究中,使用2021年3月的在线调查,我们评估了健康信念模型中的变量(严重程度、易感性、益处、障碍和行动线索),以及父母的社会人口统计学特征、既往新冠肺炎感染、新冠肺炎大流行导致的失业以及家庭中是否有医护人员。还评估了家庭中儿童的总数及其慢性健康状况。进行多变量逻辑回归,以评估儿童接种新冠肺炎疫苗的意图以及与其他变量的相关性。主要调查结果调查回复率为32.30%(595/1842)。大多数参与者是白人(72.1%),31-40岁(55.46%),已婚或同居(90.25)。在595名有3-15岁孩子的母亲中,38.32%的人无意为孩子接种疫苗。与意向相关的主要因素是感知易感性(P=0.002)、益处(P<0.001)、障碍(P<0.001。最有力的行动提示是提供足够的信息,然后遵循医生的建议。结论增加儿童疫苗接种的策略在于说服父母由儿科医生和其他医疗保健提供者提供有关疫苗安全性、有效性和副作用的可靠信息。
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引用次数: 7
Situation analysis of the pharmacovigilance system in Nepal using the indicator-based pharmacovigilance assessment tool (IPAT) 使用基于指标的药物警戒评估工具(IPAT)对尼泊尔药物警戒系统的情况分析
IF 0.7 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2021-10-13 DOI: 10.1093/jphsr/rmab054
N. Jha, Subish Palaian, Prabakaran Shankar, S. K. C., Pan Bahadur Kshetry
The aim of this study was to assess the national and regional pharmacovigilance centres in Nepal in terms of their policy frameworks, structure and functioning. A descriptive cross-sectional study was conducted during January 2021 among regional pharmacovigilance centres, and the national pharmacovigilance centre and the Ministry of Health and Population. The indicator-based pharmacovigilance assessment tool (IPAT) consisting of 43 indicators (26 core and 17 supplementary) assessing different aspects of pharmacovigilance was used. Of a total of 14 candidates representing regional pharmacovigilance centres, 12 agreed to participate. The national pharmacovigilance centre located at the Department of Drug Administration had an acceptable level of infrastructure and manpower but poor functioning and weak collaboration with regional centres. There are no policies and procedures specifically related to pharmacovigilance and no requirement for pharmaceutical companies to report adverse drug reactions (ADRs). The national centre received only 42 ADR reports during the evaluation period. The regional centres are mostly located (10 out of 14) in the Kathmandu Valley and had qualified manpower and basic resources. There were poor process indicators suggesting problems with functioning in terms of ADR reporting, signal generation and drug safety communication. Underreporting of ADRs, weak processes and poor coordination among centres limit functioning of the system. Creating more awareness, involving consumers and pharmaceutical companies in the reporting process, and conducting more training programmes are needed for the proper functioning of pharmacovigilance services in Nepal.
本研究的目的是评估尼泊尔国家和区域药物警戒中心的政策框架、结构和功能。2021年1月,在区域药物警戒中心、国家药物警戒中心以及卫生和人口部之间进行了一项描述性横断面研究。采用基于指标的药物警戒性评估工具(IPAT),由43个指标(26个核心指标和17个补充指标)组成,评估药物警戒性的不同方面。在代表区域药物警戒中心的14个候选国家中,12个国家同意参加。设在药品管理局的国家药物警戒中心的基础设施和人力水平尚可接受,但功能差,与各区域中心的合作薄弱。没有专门与药物警戒相关的政策和程序,也没有要求制药公司报告药物不良反应(adr)。国家中心在评估期间仅收到42份药品不良反应报告。这些区域中心大多位于加德满都谷地(14个中心中的10个),拥有合格的人力和基本资源。流程指标较差,表明在不良反应报告、信号产生和药品安全沟通方面存在运作问题。少报adr、流程薄弱和中心间协调不力限制了该系统的运作。尼泊尔需要提高认识,让消费者和制药公司参与报告过程,并开展更多的培训规划,才能使药物警戒服务正常运作。
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引用次数: 2
A literature review of pharmacist’s impact on lifestyle modifications among obese, hypertensive patients 药师对肥胖、高血压患者生活方式改变影响的文献综述
IF 0.7 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2021-10-05 DOI: 10.1093/jphsr/rmab053
Yaran K Gonzalez Gonzalez, Kristen Yaun, Pooja Shah, G. Iglesias, G. Hale, N. Khanfar
Previous trials have confirmed a positive relationship between obesity and hypertension. The purpose of this article is to identify the impact of pharmacists in lifestyle adherence among obese, hypertensive patients. A literature search was performed at an academic institution using secondary databases, PubMed/MEDLINE and EBSCOhost. Reviews, observational and experimental reports published in English between 2010 and 2020 were included. Terms searched were pharmacy, pharmacist, lifestyle modifications, adherence, compliance, hypertension, obesity, consultation, intervention. Effect on lifestyle modifications consisted of change in blood pressure values, weight, body mass index, diet/sodium intake and/or exercise. Six hundred seventy-five articles were reviewed with 10 meeting inclusion criteria. The role of a pharmacist has a positive impact on compliance in lifestyle adherence with obese, hypertensive patients. Additionally, age, gender marital status, education, monthly income, knowledge level and beliefs of hypertension and co-morbidities all can affect adherence to lifestyle modifications. The pharmacist has a vital role in the management of hypertension and obesity through frequent interactions with patients to increase adherence to lifestyle modifications.
先前的试验已经证实肥胖和高血压之间存在正相关关系。本文的目的是确定药剂师对肥胖、高血压患者坚持生活方式的影响。在学术机构使用PubMed/MEDLINE和EBSCOhost二级数据库进行文献检索。包括2010年至2020年间以英文发表的综述、观察和实验报告。搜索的术语包括药房、药剂师、生活方式改变、依从性、依从性,高血压、肥胖、咨询、干预。对生活方式改变的影响包括血压值、体重、体重指数、饮食/钠摄入量和/或运动的变化。共审查了六百七十五篇文章,其中10篇符合入选标准。药剂师的作用对肥胖、高血压患者的生活方式依从性有积极影响。此外,年龄、性别、婚姻状况、教育程度、月收入、知识水平以及对高血压和合并症的信念都会影响对生活方式改变的坚持。药剂师通过与患者频繁互动,提高对生活方式改变的依从性,在高血压和肥胖的管理中发挥着至关重要的作用。
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引用次数: 0
Corrigendum to: Determining the impact of vitamin C use with the common cold on loss of labour and medical treatment costs for Turkey 确定普通感冒患者服用维生素C对土耳其劳动力损失和医疗费用的影响的勘误
IF 0.7 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2021-09-17 DOI: 10.1093/jphsr/rmab052
Gülpembe Og˘uzhan, S. Ökçün, M. Kurnaz, G. Koçkaya, S. S¸en, Burçin Kahveci Kaplan, I˙˙smail Mete S¸aylan
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引用次数: 0
Mental well-being promotion by Australian community pharmacists: what’s happening and what needs to be done? 澳大利亚社区药剂师促进心理健康:正在发生什么,需要做什么?
IF 0.7 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2021-09-04 DOI: 10.1093/jphsr/rmab051
V. Suppiah, Fiona S. Kelly, Oliver Watt, A. Wheeler, E. Hotham, S. McMillan
Abstract Objectives This study aimed to explore the range of activities provided by community pharmacists for promoting mental well-being in Australia. Methods An online survey was developed and piloted by 2 community pharmacists, 1 representative from the Pharmaceutical Society of Australia and 11 pharmacy students for content and face validity. Community pharmacists were recruited via direct emails to pharmacy groups and social media between November 2019 and January 2020. Descriptive statistics and chi-squared analyses were conducted. Key findings Data were analysed from 85 pharmacists (of 115 total pharmacy staff respondents). Although 40% reported working in a pharmacy that promoted mental well-being, most (88.2%) were not involved in such activities. However, most respondents (88.0%) identified community pharmacy as a suitable setting to promote mental well-being. Barriers to mental well-being promotion included busy pharmacy environment with competing priorities, a lack of staff training and confidence in discussing mental well-being and stigma associated with mental illness. Conclusions Community pharmacy presents a suitable setting to promote mental well-being. However, pharmacists may not be utilizing their full range of skills and knowledge in promoting a national health priority. This study identified opportunities for increased pharmacist-led promotion of mental well-being, particularly given the emerging mental health impacts of the COVID-19 pandemic. The pandemic has highlighted the growing urgency for mental health-friendly health workers across the sector including the community pharmacy workforce to engage consumers about their mental well-being.
摘要目的本研究旨在探索澳大利亚社区药剂师为促进心理健康提供的活动范围。方法由2名社区药剂师、1名澳大利亚药学会代表和11名药学专业学生进行内容和面孔有效性在线调查。2019年11月至2020年1月,社区药剂师通过直接向药房团体和社交媒体发送电子邮件的方式招募。进行描述性统计和卡方分析。主要调查结果分析了85名药剂师(115名药房员工受访者)的数据。尽管40%的人报告在促进心理健康的药房工作,但大多数人(88.2%)没有参与此类活动。然而,大多数受访者(88.0%)认为社区药房是促进心理健康的合适场所。促进心理健康的障碍包括繁忙的药房环境,优先事项相互竞争,缺乏员工培训,对讨论心理健康缺乏信心,以及与心理疾病相关的污名。结论社区药房是促进心理健康的适宜场所。然而,药剂师可能没有充分利用他们的技能和知识来促进国家卫生优先事项。这项研究确定了增加药物促进心理健康的机会,特别是考虑到新冠肺炎大流行对心理健康的新影响。疫情凸显了包括社区药房工作人员在内的整个行业的心理健康友好型卫生工作者越来越迫切地需要让消费者了解他们的心理健康。
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引用次数: 0
Value-based drug price schemes: a welfare analysis 基于价值的药品价格方案:福利分析
IF 0.7 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2021-08-30 DOI: 10.1093/jphsr/rmab043
L. Levaggi, Rosella Levaggi
The market for innovative drugs is characterized by high levels of regulation, whose impact on the market is not neutral. On the one hand, strict regulation may in fact adversely affect incentives to develop new and better products; on the other hand, high prices may drive an unsustainable increase in healthcare costs. This trade-off is particularly important in Europe, where about 75% of drugs costs are financed by the public sector. We develop a simple model that allows to compare the impact of different listing and pricing strategies on the social value of innovative drugs, the consumer surplus and the expected profit of the industry. Uncertainty in the expected price, as well as other forms of access regulation, may lead to a fairer division of the social value between patients and the industry, at the cost of leaving some of the potential value of the drug unexploited. The regulator may improve value for money if it is prepared either to restrict access to the drug or to reduce the expected price. In both cases, the number of groups of patients treated may be different from the social optimum.
创新药物市场的特点是高度监管,对市场的影响不是中性的。一方面,严格的监管实际上可能对开发新的更好产品的激励产生不利影响;另一方面,高价格可能会导致医疗成本的不可持续增长。这种权衡在欧洲尤为重要,因为欧洲约75%的药品成本由公共部门提供资金。我们开发了一个简单的模型,可以比较不同的上市和定价策略对创新药物的社会价值、消费者剩余和行业预期利润的影响。预期价格的不确定性,以及其他形式的准入监管,可能会导致患者和行业之间更公平地划分社会价值,代价是药物的一些潜在价值未被开发。如果监管机构准备限制药物的获取或降低预期价格,它可能会提高资金的价值。在这两种情况下,接受治疗的患者组的数量可能与社会最优值不同。
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引用次数: 1
Cost-effectiveness analysis for the parenteral anticoagulants in Jordan 约旦非肠道抗凝剂的成本效益分析
IF 0.7 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2021-08-19 DOI: 10.1093/jphsr/rmab045
Shatha Alquraan, Feras Darwish El-Hajji
Pharmacoeconomic dimensions linking clinical effectiveness of parenteral anticoagulants for management of acute venous thromboembolism (VTE) and cost of treatment are needed to support choices by healthcare providers. The objective of the study was to conduct a cost-effectiveness analysis for 5-day treatment with parenteral anticoagulants in Jordan. Cost-effectiveness analysis was conducted based on decision analysis tree model. The perspective was the payer, considering direct medical costs. Probabilities of failure of treatment and major bleeding were derived from published clinical studies. Costs were estimated based on 2019 prices in Jordan. The average cost of VTE hospitalization and major bleeding management in Jordan were 2324.00 US$ and 3347.40 US$, respectively. Bemiparin was associated with the highest clinical efficacy and lowest probability of major bleeding. Nadroparin had the lowest clinical efficacy, while tinzaparin was found to have the highest risk of major bleeding. Bemiparin had the lowest average cost-effectiveness ratio (101.63 US$/success) and nadroparin had the highest cost-effectiveness ratio (295.56 US$/success). Throughout the sensitivity analysis calculations, bemiparin and nadroparin had the lowest and highest cost of treatment, respectively. The cost of parenteral anticoagulant drugs, the same as many other drugs, does not always correlate with cost of VTE treatment. Other direct medical costs (e.g. treatment failure and management of bleeding) have a high contribution to the total cost calculation. Pharmacoeconomically, bemiparin is the dominant cost-effective parenteral anticoagulant in Jordan, while nadroparin is the dominated one.
需要将胃肠外抗凝剂治疗急性静脉血栓栓塞症(VTE)的临床有效性与治疗成本联系起来的药物经济学维度,以支持医疗保健提供者的选择。本研究的目的是在约旦进行为期5天的胃肠外抗凝剂治疗的成本效益分析。基于决策分析树模型进行成本效益分析。考虑到直接医疗费用,观点是付款人。治疗失败和大出血的概率来源于已发表的临床研究。成本是根据约旦2019年的价格估算的。约旦VTE住院和大出血治疗的平均费用分别为2324.00美元和3347.40美元。贝米帕林具有最高的临床疗效和最低的大出血概率。那屈肝素的临床疗效最低,而廷扎帕林的大出血风险最高。贝米帕林的平均成本效益比最低(101.63美元/成功),那曲帕林的成本效益比最高(295.56美元/失败)。在整个敏感性分析计算中,贝米帕林和那屈肝素的治疗成本分别最低和最高。与许多其他药物一样,胃肠外抗凝药物的成本并不总是与VTE治疗的成本相关。其他直接医疗费用(如治疗失败和出血管理)对总费用计算的贡献很大。在药物经济学上,贝米帕林是约旦主要的成本效益高的胃肠外抗凝剂,而那屈肝素是主要的。
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引用次数: 0
A pilot study to assess the need for new hospital pharmaceutical services in Algerian patients and physicians’ perspective 从阿尔及利亚患者和医生的角度评估新医院药品服务需求的试点研究
IF 0.7 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2021-08-17 DOI: 10.1093/jphsr/rmab042
M. Chelghoum, W. Khitri, F. Kadouri, Khedra Chaouche
The objective of this study was to assess the needs for pharmaceutical services from the perspectives of physicians and patients in the hospital setting and to contribute to the implementation of new hospital pharmacy activities. A cross-sectional descriptive study was carried out among the doctors and patients encountered in hospital departments in Sidi Bel Abbès (Algeria); each service was evaluated using a Likert scale. Associated characteristics with an important need were evaluated by univariate analysis and binary logistic regression. All pharmaceutical services were important to the patients, particularly providing treatment advice and therapeutic education. Women presented an important need for insurance of the availability of pharmaceutical products (P = 0.02) and lifestyle and dietetic information (P = 0.05). High frequency of taking medication was associated with an important need for information about drug interactions (P = 0.005). Patient-oriented pharmaceutical services were not important to the physicians who considered drug information and therapeutic education to be the most important need. To implement patient-centred services, it is important to improve the contact between pharmacists and physicians and to provide information about pharmaceutical services that can benefit patients. Implementation of new practices in university hospital is more feasible than in public health facilities.
本研究的目的是评估医院内医生和病人对药学服务的需求,并为实施新的医院药学活动作出贡献。对Sidi Bel abb(阿尔及利亚)医院部门遇到的医生和病人进行了横断面描述性研究;使用李克特量表对每项服务进行评估。通过单变量分析和二元逻辑回归评估与重要需求相关的特征。所有药物服务对患者都很重要,特别是提供治疗建议和治疗教育。妇女对药品可得性保险(P = 0.02)和生活方式和饮食信息保险(P = 0.05)有重要需求。服药频率高与对药物相互作用信息的重要需求相关(P = 0.005)。以患者为中心的药学服务对医生来说并不重要,他们认为药物信息和治疗教育是最重要的需求。为了实施以患者为中心的服务,重要的是要改善药剂师和医生之间的联系,并提供有利于患者的药学服务信息。在大学医院实施新做法比在公共卫生机构更可行。
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引用次数: 0
How to have a manuscript accepted for publication 如何让稿件被接受发表
IF 0.7 Q4 HEALTH CARE SCIENCES & SERVICES Pub Date : 2021-07-30 DOI: 10.1093/jphsr/rmab032
A. Wertheimer
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引用次数: 0
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Journal of Pharmaceutical Health Services Research
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