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Neovaginoplasty With Nile Tilapia Skin Graft in A Patient With Gonadal Dysgenesis: A Case Report 性腺发育不良患者的尼罗罗非鱼皮移植阴道成形术:病例报告。
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-01 DOI: 10.1016/j.jpag.2024.07.008
Samuel Soares Coutinho BM , Luana Darc de Menezes Braga BM , Mylena Evilyn Sousa Costa BM , Mariana Oliveira Veloso BM , Ana Paula Negreiros Nunes Alves PhD , Edmar Maciel Lima Júnior MSc , Zenilda Vieira Bruno PhD , Manoel Odorico de Moraes Filho PhD , Carlos Roberto Koscky Paier PhD , Felipe Augusto Rocha Rodrigues PhD , Leonardo Robson Pinheiro Sobreira Bezerra PhD

Background

Gonadal dysgenesis, a genetic condition characterized by incomplete of defective formation of the gonads, can present with vaginal agenesis in individuals with 46, XY karyotype.

Case

We report an innovative intervention in the management of vaginal agenesis in a 19-year-old female with gonadal dysgenesis. Despite initial attempts with vaginal dilators, the patient presented unresponsive, leading to the adoption of a neovaginoplasty using Nile Tilapia Fish Skin (NTFS) as graft. The procedure, based on the McIndoe technique, involved the creation of a 10 cm x 3 cm vaginal canal with an NTFS-wrapped acrylic mold without complications.

Conclusion

The use of NTFS as a graft for neovaginoplasty in gonadal dysgenesis, a novel approach not previously reported in medical literature for this diagnosis, demonstrated favorable outcomes in terms of functionality and patient well-being.
背景:性腺发育不良是一种遗传性疾病,其特点是性腺形成不完全或有缺陷,46,XY 核型患者可能会出现阴道发育不良:我们报告了在治疗一名患有性腺发育不良的 19 岁女性阴道无阴道症时所采取的创新干预措施。尽管最初尝试过使用阴道扩张器,但患者没有任何反应,因此我们采用了尼罗罗非鱼皮(NTFS)作为移植物的阴道成形术。该手术以 McIndoe 技术为基础,用包裹 NTFS 的丙烯酸模具创建了一个 10 厘米 x 3 厘米的阴道,没有出现并发症:讨论:在性腺发育不良患者的阴道成形术中使用 NTFS 作为移植物,是医学文献中从未报道过的一种新方法。
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引用次数: 0
Perioperative and Operative Considerations for Minimally Invasive Surgery in Pediatric and Adolescent Gynecology 儿科和青少年妇科微创手术的围手术期和手术注意事项。
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-01 DOI: 10.1016/j.jpag.2024.07.006
Heather Appelbaum MD, FACOG
Minimally invasive surgery (MIS) techniques, including vaginoscopy, laparoscopy, and robotic-assisted surgery, have revolutionized the field of gynecology, offering numerous benefits, such as reduced postoperative pain, shorter hospital stays, and faster recovery. Although these techniques are widely employed in adult gynecologic surgery, their application in pediatric and adolescent patients requires careful consideration due to anatomic differences, patient size, and specific surgical requirements in children. Various aspects of MIS in pediatric and adolescent gynecology, including patient positioning, laparoscopic and robotic instrument choices, trocar placement, surgical techniques, and perioperative pediatric adaptations to MIS, are discussed. The findings highlight the unique challenges and opportunities in performing MIS for pediatric and adolescent patients undergoing gynecologic surgery, emphasizing the need for specialized training and multidisciplinary collaboration.
微创手术(MIS)技术,包括阴道镜、腹腔镜和机器人辅助手术(RAS),为妇科领域带来了革命性的变化,具有减少术后疼痛、缩短住院时间和加快康复等诸多优点。虽然这些技术被广泛应用于成人妇科手术,但由于解剖学差异、患者体型以及儿童的特殊手术要求,在儿童和青少年患者中应用这些技术还需慎重考虑。本文讨论了 MIS 在小儿和青少年妇科中的各个方面,包括患者定位、腹腔镜和机器人器械的选择、套管放置、手术技巧以及围手术期小儿对 MIS 的适应性。研究结果突显了为接受妇科手术的儿童和青少年患者实施 MIS 所面临的独特挑战和机遇,强调了专业培训和多学科合作的必要性。
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引用次数: 0
Myth Busting: Virginity and the Hymen
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-01 DOI: 10.1016/j.jpag.2025.01.012
Paula J Adams Hillard MD (JPAG Editor-in-ChiefShe, her, hers)
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引用次数: 0
Adult Obstetricians and Gynecologists Lack Knowledge of Anorectal Malformations—A Call for Action 成人妇产科医生对肛门直肠畸形缺乏了解--呼吁采取行动:妇科医生对肛门直肠畸形缺乏了解。
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-01 DOI: 10.1016/j.jpag.2024.09.001
Shruthi Srinivas MD, MPH , Jenna Wilson BS , Katherine C. Bergus MD, MPH , Chelsea Kebodeaux MD , Kate McCracken MD , Richard J. Wood MD , Geri Hewitt MD

Objective

Patients with anorectal malformations (ARMs) may have concurrent gynecologic abnormalities. As patients grow, they typically transition from pediatric subspeciality care and seek adult obstetrics and gynecology (OB/GYN)-related services. We aimed to assess adult OB/GYN physicians’ knowledge, competency, and comfort regarding meeting the sexual and reproductive health care needs of patients with ARMs.

Methods

We performed a cross-sectional observational survey-based study of graduates from a single academic OB/GYN residency program from 2013 to 2022. Physicians were surveyed on experience, comfort, and challenges with caring for patients with ARMs and given a knowledge assessment. Descriptive and comparative statistics between those who did and did not complete a Pediatric and Adolescent Gynecology (PAG) rotation were generated.

Results

There were 59 respondents (53.6%). Fewer than half (39.0%) reported caring for a patient with an ARM, an appendicovesicostomy (12.3%), or an appendicostomy (5.4%). Most felt uncomfortable (80.4%) or felt they lacked competence in caring for these patients (81.8%). Most (64.3%) felt that ARMs should be discussed in residency. Only 1 physician (1.7%) answered all questions in the knowledge assessment correctly; 33.9% did not answer any question correctly. On subgroup analysis, more physicians who had completed a pediatric and adolescent gynecology rotation recalled learning about ARMs (83.3% vs 51.9%, P = .03); however, there were no differences in experience, comfort, competence, or willingness to learn.

Conclusion

OB/GYN providers report a lack of knowledge and comfort in caring for patients with ARMs. Development of a standardized OB/GYN residency curriculum and education for practicing OB/GYN physicians is necessary to allow access to knowledgeable sexual and reproductive health for this patient population.
目的:肛门直肠畸形(ARM)患者可能同时伴有妇科异常。随着患者的成长,他们通常会从儿科亚专科护理过渡到寻求成人妇产科相关服务。我们的目的是评估成人妇产科医生在满足 ARM 患者的性健康和生殖健康护理需求方面的知识、能力和舒适度:方法:我们对 2013-2022 年间来自单一学术性妇产科住院医师培训项目的毕业生进行了一项横断面观察调查研究。我们调查了医生在护理 ARM 患者方面的经验、舒适度和挑战,并对他们进行了知识评估。对完成和未完成儿科和青少年妇科(PAG)轮转的医生进行了描述性和比较性统计:共有 59 名受访者(53.6%)。只有不到一半的受访者(39.0%)表示护理过患有 ARM、阑尾切除术(12.3%)或阑尾造口术(5.4%)的患者。大多数人在护理这些病人时感到不舒服(80.4%)或觉得自己缺乏能力(81.8%)。大多数人(64.3%)认为应在住院医师培训中讨论 ARM。只有一名医生(1.7%)正确回答了知识评估中的所有问题;33.9%的医生没有正确回答任何问题。在分组分析中,更多完成 PAG 轮转的医生回忆起学习过 ARMs(83.3 vs 51.9%,P=0.03);但在经验、舒适度、能力或学习意愿方面没有差异:结论:妇产科医护人员在护理 ARM 患者方面缺乏知识和舒适感。有必要制定标准化的妇产科住院医师课程并对妇产科执业医师进行教育,使这一患者群体能够获得性健康和生殖健康方面的知识。
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引用次数: 0
Mother-Daughter Dyads’ Perceptions of Contraception 母女二人组对避孕的看法。
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-01 DOI: 10.1016/j.jpag.2024.09.005
Caroline L Katzman MD , Jessica C Sims MD , Julen N Harris MD, MPH , Susan L Rosenthal PhD , Jenny KR Francis MD, MPH

Study Objective

In an increasing number of states, parents must provide permission for their daughters under 18-years-old to start contraception. We sought to understand perceptions among mother-daughter dyads about sources of information, and to describe dyadic interactions when discussing contraception.

Methods

Dyads were recruited from an adolescent medicine clinic in Dallas, TX. A semistructured joint interview was conducted with each dyad. Interviews were recorded, transcribed, and coded through an iterative approach.

Results

There were 11 dyadic interviews (22 participants). Sources of information about contraception included mothers, healthcare providers (HCPs), friends/family, school, and individualized learning. Dyads identified distinct purposes and limitations of each source. Mothers noted the importance of supporting their daughter's development and specific needs. Often these conversations began with a discussion of menstrual management. Information from friends/family was overwhelmingly anecdotal. Schools and HCPs were viewed as trusted sources, and the internet/social media as possibly inaccurate or misleading. Dyads described several risks and benefits of different methods. Minimal conflict was noted.

Conclusion

These results provide rich information about how mother-daughter dyads view contraception in joint discussion. It is important to ensure that accurate stories about contraception are accessible and teaching health literacy would be helpful. Menstrual management appears to be an acceptable starting point to discuss contraception. Schools and HCPs are trusted sources and measures should be taken to ensure teaching is accurate, developmentally appropriate and teaches evaluation of online information. Regardless of parental consent laws for adolescent contraception, engaging caregivers in the process can help support adolescent contraceptive decision-making.
研究目的:在越来越多的州,父母必须允许未满 18 岁的女儿开始避孕。我们试图了解母女二人组对信息来源的看法,并描述二人组在讨论避孕问题时的互动情况:方法:我们从德克萨斯州达拉斯市的一家青春期医学诊所招募了母女二人组。对每对母女进行了一次半结构化联合访谈。对访谈进行记录、转录,并通过迭代法进行编码:结果:共进行了 11 次双人访谈(22 名参与者)。避孕信息的来源包括母亲、医疗保健提供者(HCPs)、朋友/家人、学校和个性化学习。二元组确定了每种信息来源的不同目的和局限性。母亲们指出,支持女儿的发展和特殊需求非常重要。这些对话通常从讨论月经管理开始。来自朋友/家人的信息绝大多数是传闻。学校和保健医生被视为可信的信息来源,而互联网/社交媒体则可能不准确或具有误导性。各小组描述了不同方法的风险和益处。冲突极少:这些结果为母女二人在共同讨论中如何看待避孕提供了丰富的信息。重要的是要确保人们能够获得有关避孕的准确信息,而健康知识教育也会有所帮助。月经管理似乎是讨论避孕的一个可接受的起点。学校和保健医生是值得信赖的信息来源,应采取措施确保教学内容准确、适合发展需要,并教授如何评估在线信息。无论青少年避孕是否征得父母同意,让照顾者参与这一过程有助于支持青少年避孕决策。
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引用次数: 0
Sexual and Reproductive Health Goals and the 2030 Global Agenda for Sustainable Development: Progress, Prospects, and Challenges 性与生殖健康目标和 2030 年全球可持续发展议程:进展、前景和挑战》。
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-01 DOI: 10.1016/j.jpag.2024.09.002
Areej Hassan MD, MPH , Sarah Golub MD, MPH
Today, it is globally recognized that sexual and reproductive health is a human rights issue critical to economic growth and stability, ending poverty, and fostering sustainable development. Calls for improving sexual and reproductive health, including a spotlight on adolescents and young women, are highlighted in the Sustainable Development Goals (SDG) adopted by the United Nations in 2015. In this commentary, we aim to (1) briefly review the history and objectives of global development goals, (2) review the adolescent health-related Sustainable Development Goal targets and indicators with a focus on sexual and reproductive health, (3) discuss global progress and challenges in achieving target measures, and (4) examine action steps that clinicians can take to accelerate progress.
如今,全球公认性健康和生殖健康是一个人权问题,对经济增长和稳定、消除贫困和促进可持续发展至关重要。联合国在 2015 年通过的可持续发展目标(SDGs)中强调了改善性健康与生殖健康的要求,包括关注青少年和年轻女性。在本评论中,我们旨在:(1)简要回顾全球发展目标的历史和目标;(2)回顾与青少年健康相关的可持续发展目标的具体目标和指标,重点关注性健康和生殖健康;(3)讨论在实现具体目标措施方面的全球进展和挑战;以及(4)研究临床医生可以采取的行动步骤,以加快进展。
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引用次数: 0
Long-Term Outcomes of Ovary Preserving Procedure for Neonatal Ovarian Cysts 新生儿卵巢囊肿保留卵巢手术的长期疗效。
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-01 DOI: 10.1016/j.jpag.2024.09.007
XiaoLi Chen, DuoTe Cai, Yi Chen, BinBin Yang, YueBin Zhang, QingJiang Chen, ZhiGang Gao

Objective

We aim to evaluate the long-term outcomes of ovarian preserving surgery for neonatal ovarian cysts.

Method

The clinical data of neonatal ovarian cysts treated in our hospital from January 2015 to December 2022 were retrospectively analyzed.

Results

Our study included 22 patients, of which 21 were unilateral and 1 was bilateral. There were 13 cases of simple cysts and 9 cases of complex cysts, and one cyst changed from simple to complex. The mean largest diameter of simple cysts was 5.7 ± 2.1 cm, and that of complex cysts was 4.6 ± 2.0 cm. There was no significant difference between the two groups (P = .2264). Among the 22 patients, 21 underwent laparoscopic cystectomy. The only patient with bilateral cysts underwent percutaneous drainage of the right simple cyst. Twenty-one histological specimens were reviewed, of which 18 (85.7%) contained viable ovarian tissues. Five cases lost follow-up after surgery, and the remaining 17 cases had a follow-up period of 6 months to 5 years. The last ultrasound follow-up showed that 9 cases had bilateral normal ovaries, and 8 cases lost the ipsilateral ovary. The ovarian preservation rate of simple cyst was 90% (9/10), which was significantly higher than that of complex cyst (12.5%, 1/8) (P = .003).

Conclusions

Simple cysts (≥4 cm) had an excellent prognosis, with a long-term ovarian preservation rate of 90%. The long-term ovarian preservation rate of complex cysts after surgery was relatively low. Our study suggested that surgical treatment did not increase the chances of preserving the ovaries of patients with complex cysts.
目的:评估新生儿卵巢囊肿保留卵巢手术的长期疗效:旨在评估新生儿卵巢囊肿保卵巢手术的远期疗效:方法:回顾性分析2015年1月至2022年12月在我院接受治疗的新生儿卵巢囊肿的临床资料:本研究共纳入22例患者,其中21例为单侧,1例为双侧。其中13例为单纯性囊肿,9例为复杂性囊肿,1例囊肿由单纯性转变为复杂性。单纯性囊肿的平均最大直径为(5.7±2.1)厘米,复杂性囊肿的平均最大直径为(4.6±2.0)厘米。两组之间无明显差异(P=0.2264)。22 名患者中,21 人接受了腹腔镜膀胱切除术。唯一一名双侧囊肿患者接受了右侧单纯囊肿经皮引流术。21份组织学标本接受了复查,其中18份(85.7%)含有存活的卵巢组织。5 例患者术后失去随访,其余 17 例患者的随访时间为 6 个月至 5 年。最后一次超声随访显示,9 例双侧卵巢正常,8 例失去同侧卵巢。单纯性囊肿的卵巢保留率为90%(9/10),明显高于复杂性囊肿(12.5%,1/8)(P=0.003):简单囊肿(≥ 4 厘米)预后良好,卵巢长期保留率为 90%。复杂囊肿术后卵巢长期保留率相对较低。我们的研究表明,手术治疗并不能增加复杂囊肿患者保留卵巢的机会。
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引用次数: 0
Continuation of the Levonorgestrel-Releasing Intrauterine Device Among Adolescents With Endometriosis 患有子宫内膜异位症的青少年继续使用左炔诺孕酮释放宫内节育器。
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-01 DOI: 10.1016/j.jpag.2024.10.005
Jessica Y. Shim MD , Carly E. Milliren MPH , Amy D. DiVasta MD, MMSc

Study Objective

To estimate the 1-year continuation rate of the levonorgestrel-releasing intrauterine device (LNG-IUD) in adolescents with endometriosis, and the frequency at which additional systemic hormonal treatment (HT) is utilized.

Methods

A retrospective cohort study was performed of patients aged 12-21 years who underwent laparoscopy for endometriosis and LNG-IUD insertion at a single tertiary care institution between 2018 and 2021.

Results

We evaluated 224 adolescents (mean age = 17.0, SD = 1.8 years) who underwent LNG-IUD placement during laparoscopic evaluation for endometriosis. Stage I endometriosis was most common (84.4%), followed by stage II (13.0%). Of 221 with follow-up, 208 (94.1%) had HT added or continued postsurgery. The most common additional HT was norethindrone acetate (42.5%), followed by combined hormonal contraceptives (34.8%). The 1-year LNG-IUD continuation rate was 92.0%. There were 18 IUD removals (8%) by 1 year, and the median time to removal was 118 days (interquartile range = 159; range 8-293). Use of additional HT was associated with a lower hazard of IUD removal within the first year of use (hazard ratio = 0.19, 95% confidence interval: 0.06-0.56, P < .001).

Conclusion

The majority of adolescents used the LNG-IUD with additional systemic HT for endometriosis management. While overall continuation was high, adolescents who were using LNG-IUD and HT were more likely to continue LNG-IUD than those who were not utilizing additional HT.
研究目的估算患有子宫内膜异位症的青少年使用左炔诺孕酮释放宫内节育器(LNG-IUD)1年的持续率,以及额外使用全身激素治疗(HT)的频率:我们对2018年至2021年间在一家三级医疗机构接受腹腔镜子宫内膜异位症和LNG-宫内节育器植入术的12-21岁患者进行了一项回顾性队列研究:我们评估了224名青少年(平均年龄=17.0岁,SD=1.8岁),他们在腹腔镜评估子宫内膜异位症期间接受了LNG-IUD置入术。I期子宫内膜异位症最常见(84.4%),其次是II期(13.0%)。在 221 例接受随访的患者中,208 例(94.1%)在手术后增加或继续使用 HT。最常见的附加 HT 是醋酸炔诺酮(42.5%),其次是复合激素避孕药(34.8%)。液化天然气宫内节育器的 1 年延续率为 92.0%。1 年内共取出 18 个宫内节育器(8%),取出时间中位数为 118 天(IQR=159;范围为 8-293)。使用额外的 HT 与使用后第一年内取出宫内节育器的较低风险相关(HR = 0.19,95% CI:0.06-0.56,p 结论:大多数青少年在使用液化天然气宫内节育器治疗子宫内膜异位症的同时,还使用了其他系统性 HT。虽然总体持续率较高,但使用 LNG-IUD 和 HT 的青少年比未使用额外 HT 的青少年更有可能继续使用 LNG-IUD。
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引用次数: 0
FIGIJ and NASPAG Advocacy Statement-Eliminating the Persistent Misconception of the “Virgin Hymen” FIGIJ 和 NASPAG 宣传声明--消除对 "处女膜 "的长期误解。
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-01 DOI: 10.1016/j.jpag.2024.08.014
Judith Celine Simms-Cendan , Angela G. Sison-Aguilar , Mariela Orti , Clara DiNunzio , Anastasia Vatopoulou , Ellen Rome , Michalina Drejza , Jasmin Jayasinghe , Daniela Ivanova Panova , Marisa Labovsky
This advocacy statement endeavors to clarify the concept of the hymen as a symbol of “virginity.” The anatomic variants of this structure precludes any correlation to prior sexual activity and the value of physical assessment of this structure is thus questioned. Moreover, physical examination of the hymen is painful, traumatic, and humiliating and is a form of gender-based violence. This statement exhorts various sectors—governments, educators, the medical community, and the general public—to discard the concept of the “virgin hymen,” avoid its use when documenting sexual abuse, and provide progressive education to affirm female sexuality.
本倡导声明旨在澄清处女膜作为 "贞洁 "象征的概念。这一结构在解剖学上的变异排除了与先前性活动的任何相关性,因此对这一结构进行物理评估的价值受到质疑。此外,对处女膜进行身体检查是一种痛苦、创伤和侮辱,是一种基于性别的暴力。本声明敦促政府、教育工作者、医学界和公众等各方面摒弃 "处女膜 "的概念,在记录性虐待时避免使用这一概念,并提供渐进式教育,以肯定女性的性行为。
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引用次数: 0
NASPAG Clinical Consensus on Nonsexually Acquired Genital Ulcers (Vulvar Aphthous Ulcers) NASPAG 关于非性获得性生殖器溃疡(外阴无菌性溃疡)的临床共识。
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-01 DOI: 10.1016/j.jpag.2024.08.010
Jacquelyn R. Evans DO , Amanda V. French MD
The objective of this document is to provide guidance on the recognition, diagnosis and management of non-sexually acquired genital ulcers in the pediatric and adolescent patient. Commonly known as genital or vulvar aphthous ulcers, lesions are typically seen in the peri‑menarchal population, are exquisitely painful, generally self-limited and managed with supportive care. Details of ulcer physical appearance, proposed etiology and options for management are provided to familiarize clinicians with this entity, which can be alarming for patients and families.
本文件旨在为儿科和青少年患者非性生殖器溃疡的识别、诊断和治疗提供指导。生殖器溃疡俗称生殖器或外阴阿弗他溃疡,通常发生在青春期前后的人群中,疼痛剧烈,一般为自限性,并可通过支持性护理得到控制。本文详细介绍了溃疡的物理外观、病因和治疗方案,让临床医生熟悉这种可能让患者和家属感到恐慌的疾病。
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引用次数: 0
期刊
Journal of pediatric and adolescent gynecology
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