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6. Evaluating the diagnostic work-up of heavy menstrual bleeding and hemostatic efficacy of norethindrone acetate in improving menstrual suppression among adolescent girls with obesity
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-28 DOI: 10.1016/j.jpag.2025.01.018
Julia Shuford , Maeve McNamara , Anna Schwartz , Morgan Buchanan , Robert Sidonio , Nancy Sokkary , Megan Brown

Background

Adolescent obesity continues to rise in prevalence and is a risk factor for many etiologies of heavy menstrual bleeding (HMB), yet comprehensive guidelines on the evaluation and management of HMB in obese adolescents is lacking. This study aims to (1) characterize the prevalence of obesity and menstrual characteristics among adolescents presenting to the emergency department (ED) with HMB, (2) investigate the hemostatic efficacy of norethindrone acetate (NA) relative to IV conjugated estrogen in obese adolescents.

Methods

A retrospective chart review with collection of demographic and clinical data was performed, including all ED encounters (2017-2022, excluding 2020 due to COVID-19 pandemic) at three affiliates of a large tertiary children's hospital that utilized an acute HMB clinical pathway. Obesity was defined by BMI equal to or greater than the 85th percentile. Hemostatic efficacy was defined as follows: red blood cell (RBC) transfusion, tranexamic acid (TXA) utilization, and length of stay (LOS) >36 hours. TXA use was a surrogate for poorly controlled HMB at 24 hours; the clinical pathway recommended adding TXA if HMB persisted despite primary hemostatic agent at 24 hours. T tests and chi squared statistics were used to compare continuous and categorical variables, respectively. Multivariate logistic regression models were used to predict adjusted odds ratios of outcome variables (NA vs. IV conjugated estrogen) separately among all non-obese and obese individuals.

Results

Between 2017-2022, 402 adolescents were admitted from the ED for HMB with documented BMI measurements. Over half were obese. Obese adolescents disproportionately identified as Black and reported younger onset of menarche. When adjusting for admission hemoglobin, receiving NA alone was associated with significantly decreased odds of RBC transfusion (AOR: 0.265, 95% CI: 0.104-0.674; p=0.005) relative to receiving IV conjugated estrogen among non-obese individuals. When adjusting for platelet levels, receiving NA alone was associated with significantly decreased odds of TXA utilization (AOR: 0.107, 95% CI: 0.013-0.859; p=0.036) among non-obese individuals. However, among obese individuals, we observed no association with odds of transfusion (p=0.267), TXA utilization (p=0.265) or LOS >36 hours (p=0.472) by hemostatic agent.

Conclusions

In the setting of acute HMB, treatment with NA is associated with reduced odds of RBC transfusion and TXA utilization among non-obese but not obese individuals, highlighting the potential disparities in treatment response based on obesity status.
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引用次数: 0
48. Gynecology Concerns for Children and Adolescents with Genitourinary Perineal Vascular Anomalies: A Retrospective Analysis
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-28 DOI: 10.1016/j.jpag.2025.01.081
Anna Ujvary , Maya Younoszai , Xing Wang , Shane Morrison , Jonathan Perkins , Katherine Debiec

Background

We investigated the prevalence, management, and outcomes of genitourinary-perineal vascular anomalies (GUP-VAs), focusing on gynecologic concerns in pediatric patients with vulvar anatomy. We compared infantile hemangiomas (IHs) and vascular malformations (VMs) regarding symptom prevalence, functional impairment, treatment approaches, and outcomes. We hypothesized that VMs are associated with more significant gynecologic symptoms, functional impairment, and a higher likelihood of reproductive health counseling. The study aims to further understand gynecologic and developmental needs to improve clinical outcomes and personalized care.

Methods

Following IRB approval, we conducted a retrospective chart review of 119 patients treated for GUP-VAs at Seattle Children's between 1998 and 2024. Patients aged 0-21 years with vulvar anatomy and a GUP vascular anomaly diagnosis were included. Data on demographics, anatomic location, symptoms, functional impairments, treatment modalities, and gynecologic concerns were analyzed. Statistical comparisons between IHs and VMs were conducted using Mann-Whitney U tests for continuous variables and Fisher's exact test for categorical variables, focusing on symptoms, impairments, and treatment outcomes.

Results

Of the 119 patients, 98 (82.4%) had IHs and 21 (17.6%) had VMs. VMs were significantly associated with symptoms of mass (p < 0.001), dyspareunia (p = 0.030), and functional impairments such as pain (p = 0.001) and emotional concerns (p = 0.005). Observation (p = 0.003) and pharmacotherapy (p = 0.004) were more common for IHs, while more invasive treatments like sclerotherapy (p < 0.001) and excision (p = 0.057) were used more frequently for VMs. Post-treatment, patients with VMs showed significant improvements in pain (p = 0.043) and emotional well-being (p = 0.030). Gynecologic issues, such as menstrual irregularities, were prevalent in venolymphatic (100%) and lymphatic malformations (50%), while 50% of patients with lymphatic malformations reported sexual dysfunction. Contraceptive and pregnancy counseling were more common in patients with VMs, particularly those with Klippel-Trenaunay syndrome (66.7%).

Conclusions

VMs in the GUP region are associated with more severe symptoms and greater functional impairments compared to IHs. These findings highlight the physical and emotional impact of VMs and the importance of addressing gynecologic and reproductive health in this population. Treatment outcomes showed significant improvements in pain and emotional well-being, emphasizing the need for early diagnosis and multidisciplinary management to optimize patient outcomes.
{"title":"48. Gynecology Concerns for Children and Adolescents with Genitourinary Perineal Vascular Anomalies: A Retrospective Analysis","authors":"Anna Ujvary ,&nbsp;Maya Younoszai ,&nbsp;Xing Wang ,&nbsp;Shane Morrison ,&nbsp;Jonathan Perkins ,&nbsp;Katherine Debiec","doi":"10.1016/j.jpag.2025.01.081","DOIUrl":"10.1016/j.jpag.2025.01.081","url":null,"abstract":"<div><h3>Background</h3><div>We investigated the prevalence, management, and outcomes of genitourinary-perineal vascular anomalies (GUP-VAs), focusing on gynecologic concerns in pediatric patients with vulvar anatomy. We compared infantile hemangiomas (IHs) and vascular malformations (VMs) regarding symptom prevalence, functional impairment, treatment approaches, and outcomes. We hypothesized that VMs are associated with more significant gynecologic symptoms, functional impairment, and a higher likelihood of reproductive health counseling. The study aims to further understand gynecologic and developmental needs to improve clinical outcomes and personalized care.</div></div><div><h3>Methods</h3><div>Following IRB approval, we conducted a retrospective chart review of 119 patients treated for GUP-VAs at Seattle Children's between 1998 and 2024. Patients aged 0-21 years with vulvar anatomy and a GUP vascular anomaly diagnosis were included. Data on demographics, anatomic location, symptoms, functional impairments, treatment modalities, and gynecologic concerns were analyzed. Statistical comparisons between IHs and VMs were conducted using Mann-Whitney U tests for continuous variables and Fisher's exact test for categorical variables, focusing on symptoms, impairments, and treatment outcomes.</div></div><div><h3>Results</h3><div>Of the 119 patients, 98 (82.4%) had IHs and 21 (17.6%) had VMs. VMs were significantly associated with symptoms of mass (p &lt; 0.001), dyspareunia (p = 0.030), and functional impairments such as pain (p = 0.001) and emotional concerns (p = 0.005). Observation (p = 0.003) and pharmacotherapy (p = 0.004) were more common for IHs, while more invasive treatments like sclerotherapy (p &lt; 0.001) and excision (p = 0.057) were used more frequently for VMs. Post-treatment, patients with VMs showed significant improvements in pain (p = 0.043) and emotional well-being (p = 0.030). Gynecologic issues, such as menstrual irregularities, were prevalent in venolymphatic (100%) and lymphatic malformations (50%), while 50% of patients with lymphatic malformations reported sexual dysfunction. Contraceptive and pregnancy counseling were more common in patients with VMs, particularly those with Klippel-Trenaunay syndrome (66.7%).</div></div><div><h3>Conclusions</h3><div>VMs in the GUP region are associated with more severe symptoms and greater functional impairments compared to IHs. These findings highlight the physical and emotional impact of VMs and the importance of addressing gynecologic and reproductive health in this population. Treatment outcomes showed significant improvements in pain and emotional well-being, emphasizing the need for early diagnosis and multidisciplinary management to optimize patient outcomes.</div></div>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":"38 2","pages":"Pages 251-252"},"PeriodicalIF":1.7,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143520217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
40. Feasibility of Nurse Practitioner Led Vaginal Dilation Therapy: A Retrospective Cohort Study
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-28 DOI: 10.1016/j.jpag.2025.01.073
Jemimah Raffe-Devine, Aalia Sachedina, Rachel Ollivier, Natasha Prodan Bhalla, Nicole Todd

Background

Vaginal dilator therapy is the recommended first line management in patients with vaginal agenesis to increase vaginal length and improve sexual function and has been demonstrated to be highly effective with minimal risks. A barrier to successful vaginal dilator therapy is the long-term nature of treatment and the requirement for extended follow up over multiple visits. Nurse practitioner led clinics have been shown to have positive clinical outcomes in other disciplines, and use of a multidisciplinary clinic has been shown have an 88% functional success rate in patients undergoing vaginal dilator therapy. Our objective was to assess if nurse practitioner led vaginal dilator therapy is a feasible alternative to pediatric gynecologist led therapy and create an evidence-based model of care.

Methods

This is a retrospective cohort study. Electronic medical records were searched using the ICD codes for vaginal agenesis and uterine agenesis. Patients were included who had participated in vaginal dilator therapy led by a pediatric gynecologist or by a nurse practitioner at our institution's Women's Health Clinic. The primary outcomes were patient satisfaction, change in vaginal length, and sexual function throughout treatment. We also collected visit details including number and timing of visits, prescribed dilation schedule. This study was approved by the Research Ethics Board.

Results

Thirteen patients were included ranging from 15 to 33 years of age. The most common diagnosis was MRKH (92%). 92% of patients were recorded as unsatisfied with their sexual activity and vaginal length before treatment. Among patients who were seen by a nurse practitioner in association with pediatric gynecology, 80% reported normal sexual function, normal vaginal length, or overall satisfaction with vaginal dilator therapy at time of discharge. This is comparable to 84.6% of patients who were followed by either a nurse practitioner or pediatric gynecology alone. Patients were followed for a mean of 15.6 months and required a mean of 4.7 visits prior to discharge. Optimal spacing between visits was monthly with a prescribed dilation schedule of one to two times per day for 10 minutes at a time.

Conclusions

Nurse practitioner led vaginal dilator therapy is a comparable alternative to pediatric gynecology led therapy with similar outcomes as previously reported in the literature. This is a reasonable option to increase access to care for patients with vaginal agenesis without requiring routine specialist involvement.
{"title":"40. Feasibility of Nurse Practitioner Led Vaginal Dilation Therapy: A Retrospective Cohort Study","authors":"Jemimah Raffe-Devine,&nbsp;Aalia Sachedina,&nbsp;Rachel Ollivier,&nbsp;Natasha Prodan Bhalla,&nbsp;Nicole Todd","doi":"10.1016/j.jpag.2025.01.073","DOIUrl":"10.1016/j.jpag.2025.01.073","url":null,"abstract":"<div><h3>Background</h3><div>Vaginal dilator therapy is the recommended first line management in patients with vaginal agenesis to increase vaginal length and improve sexual function and has been demonstrated to be highly effective with minimal risks. A barrier to successful vaginal dilator therapy is the long-term nature of treatment and the requirement for extended follow up over multiple visits. Nurse practitioner led clinics have been shown to have positive clinical outcomes in other disciplines, and use of a multidisciplinary clinic has been shown have an 88% functional success rate in patients undergoing vaginal dilator therapy. Our objective was to assess if nurse practitioner led vaginal dilator therapy is a feasible alternative to pediatric gynecologist led therapy and create an evidence-based model of care.</div></div><div><h3>Methods</h3><div>This is a retrospective cohort study. Electronic medical records were searched using the ICD codes for vaginal agenesis and uterine agenesis. Patients were included who had participated in vaginal dilator therapy led by a pediatric gynecologist or by a nurse practitioner at our institution's Women's Health Clinic. The primary outcomes were patient satisfaction, change in vaginal length, and sexual function throughout treatment. We also collected visit details including number and timing of visits, prescribed dilation schedule. This study was approved by the Research Ethics Board.</div></div><div><h3>Results</h3><div>Thirteen patients were included ranging from 15 to 33 years of age. The most common diagnosis was MRKH (92%). 92% of patients were recorded as unsatisfied with their sexual activity and vaginal length before treatment. Among patients who were seen by a nurse practitioner in association with pediatric gynecology, 80% reported normal sexual function, normal vaginal length, or overall satisfaction with vaginal dilator therapy at time of discharge. This is comparable to 84.6% of patients who were followed by either a nurse practitioner or pediatric gynecology alone. Patients were followed for a mean of 15.6 months and required a mean of 4.7 visits prior to discharge. Optimal spacing between visits was monthly with a prescribed dilation schedule of one to two times per day for 10 minutes at a time.</div></div><div><h3>Conclusions</h3><div>Nurse practitioner led vaginal dilator therapy is a comparable alternative to pediatric gynecology led therapy with similar outcomes as previously reported in the literature. This is a reasonable option to increase access to care for patients with vaginal agenesis without requiring routine specialist involvement.</div></div>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":"38 2","pages":"Page 248"},"PeriodicalIF":1.7,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143520845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
33. Enhancing Clinical Documentation for DSD Patients: A Retrospective Evaluation of a Standardized Physical Exam Template
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-28 DOI: 10.1016/j.jpag.2025.01.066
Alexandra Herweck , Brittany Jean-Louis , Anisha Chada , Nancy Sokkary

Background

Disorders of Sex Development (DSD) encompass a wide spectrum of phenotypes, making individualized treatment challenging. The DSD Translational Research Network (TRN) has advocated for standardized documentation of physical exam findings to better tailor management. One institution's DSD clinic identified limitations in its existing documentation practices, which hindered comprehensive care. In response, the clinic developed and implemented a standardized physical exam template in the Electronic Medical Record for use in both clinical visits and the operating room, aiming to improve data collection and inform more specific treatment recommendations. The primary objective of this study is to assess the use of a newly implemented template to capture DSD-specific exam findings, in alignment with TRN recommendations. The frequency of documentation of each specific data point on the recommended exam will be evaluated.

Methods

Institutional Review Board approval was obtained. A retrospective chart review was conducted on all patients seen in the DSD clinic, including those who underwent a DSD-related surgeries, from January 2019 to June 2024. Data collected included demographics (age, race), clinical details (hormonal therapies, prior surgeries, diagnosis, karyotype, assigned/reared gender, gender identity), and the presence of gender dysphoria. Eighteen physical exam specifics recommended by the DSD TRN were evaluated, covering measurements related to internal and external genital anatomy. The use of the standardized physical exam template and whether clinical photographs were taken to document these findings were also recorded.

Results

Preliminary data revealed that prior to template implementation, common diagnoses were classical CAH and complete AIS, while the least common was 5-alpha reductase deficiency. Clitoral measurement was the most frequently assessed genital finding, recorded in 60.6% of cases. Documentation of external gonadal evaluation and urogenital sinus was recorded in only 27.2% and 21.2 % of cases respectively. Data collection from post-implementation encounters is ongoing, and we aim to compare the frequency of documentation before and after the template's introduction, along with the use of clinical photographs.

Conclusions

We anticipate that the implementation of a standardized template will significantly improve documentation of DSD-specific physical exam findings and aid in the management of this diverse population. This successful approach can be adapted by other DSD clinics, enhancing research capabilities and improving patient outcomes nationwide.
{"title":"33. Enhancing Clinical Documentation for DSD Patients: A Retrospective Evaluation of a Standardized Physical Exam Template","authors":"Alexandra Herweck ,&nbsp;Brittany Jean-Louis ,&nbsp;Anisha Chada ,&nbsp;Nancy Sokkary","doi":"10.1016/j.jpag.2025.01.066","DOIUrl":"10.1016/j.jpag.2025.01.066","url":null,"abstract":"<div><h3>Background</h3><div>Disorders of Sex Development (DSD) encompass a wide spectrum of phenotypes, making individualized treatment challenging. The DSD Translational Research Network (TRN) has advocated for standardized documentation of physical exam findings to better tailor management. One institution's DSD clinic identified limitations in its existing documentation practices, which hindered comprehensive care. In response, the clinic developed and implemented a standardized physical exam template in the Electronic Medical Record for use in both clinical visits and the operating room, aiming to improve data collection and inform more specific treatment recommendations. The primary objective of this study is to assess the use of a newly implemented template to capture DSD-specific exam findings, in alignment with TRN recommendations. The frequency of documentation of each specific data point on the recommended exam will be evaluated.</div></div><div><h3>Methods</h3><div>Institutional Review Board approval was obtained. A retrospective chart review was conducted on all patients seen in the DSD clinic, including those who underwent a DSD-related surgeries, from January 2019 to June 2024. Data collected included demographics (age, race), clinical details (hormonal therapies, prior surgeries, diagnosis, karyotype, assigned/reared gender, gender identity), and the presence of gender dysphoria. Eighteen physical exam specifics recommended by the DSD TRN were evaluated, covering measurements related to internal and external genital anatomy. The use of the standardized physical exam template and whether clinical photographs were taken to document these findings were also recorded.</div></div><div><h3>Results</h3><div>Preliminary data revealed that prior to template implementation, common diagnoses were classical CAH and complete AIS, while the least common was 5-alpha reductase deficiency. Clitoral measurement was the most frequently assessed genital finding, recorded in 60.6% of cases. Documentation of external gonadal evaluation and urogenital sinus was recorded in only 27.2% and 21.2 % of cases respectively. Data collection from post-implementation encounters is ongoing, and we aim to compare the frequency of documentation before and after the template's introduction, along with the use of clinical photographs.</div></div><div><h3>Conclusions</h3><div>We anticipate that the implementation of a standardized template will significantly improve documentation of DSD-specific physical exam findings and aid in the management of this diverse population. This successful approach can be adapted by other DSD clinics, enhancing research capabilities and improving patient outcomes nationwide.</div></div>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":"38 2","pages":"Page 246"},"PeriodicalIF":1.7,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
8. “I feel like we are walking on eggshells”: Experiences of Pediatric Residents Providing Care for Pregnant Adolescents in Texas Post-Dobbs
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-28 DOI: 10.1016/j.jpag.2025.01.041
Kyrra Engle , Zena Karagoli , Lilly Snellman , Alexis Bailey , Sreya Rahman , Deborah Babalola , Jennifer Sherwood , Margaret Wood

Background

In the year following the U.S. Supreme Court's decision in Dobbs v. Jackson Women's Health Organization to remove federal protection for abortions, new and unprecedented laws were passed related to pregnancy in Texas and elsewhere. Pediatric residents are often the first point of contact for pregnant adolescents. Examining the impact of these laws on pediatric residents is crucial to understanding gaps and promoting quality patient care in this new political landscape.

Methods

Pediatric residents were randomly selected from a Texas pediatric residency program and invited for a virtual, semi-structured, one-to-one interview with a trained study investigator between August and October 2024. Interviews explored residents' experience providing healthcare to pregnant patients and knowledge of current laws governing these interactions in Texas. All interviews were recorded, transcribed, and independently conducted using an inductive coding approach by two investigators. Themes were generated using iterative thematic analysis.

Results

Participants (n=11) included 4 third-year pediatric residents and 7 second-year pediatric residents. Inductive coding generated 34 codes consolidated into 8 themes. Data showed fear of discussing abortion was universal among residents with concerns around rules for notifying patients’ parents, and legal ramifications of documentation. Residents also discussed the emotional and moral burden of being limited in the care they can provide and awareness of the unequal impact of restrictive laws on low-income patients. Misconceptions of laws related to reproductive health care were pervasive among residents who were often informed by more senior physicians or non-academic online resources, with most residents assuming stricter versions of current policies. Overall, residents were enthusiastic about learning to care for pregnant patients and desired more clarification in their training.

Conclusions

Study findings show high levels of fear discussing abortion and common misconceptions about abortion policy among pediatric residents caring for pregnant adolescents in Texas. Given radical shifts in the U.S. policy environment, new pregnancy-focused training materials are necessary to ensure trainees feel confident caring for this patient population. Increased resident training is especially important in restrictive legal environments like Texas to prevent trainees from “over-implementing” state abortion policies and placing additional restrictions on patients' access to reproductive health services.
{"title":"8. “I feel like we are walking on eggshells”: Experiences of Pediatric Residents Providing Care for Pregnant Adolescents in Texas Post-Dobbs","authors":"Kyrra Engle ,&nbsp;Zena Karagoli ,&nbsp;Lilly Snellman ,&nbsp;Alexis Bailey ,&nbsp;Sreya Rahman ,&nbsp;Deborah Babalola ,&nbsp;Jennifer Sherwood ,&nbsp;Margaret Wood","doi":"10.1016/j.jpag.2025.01.041","DOIUrl":"10.1016/j.jpag.2025.01.041","url":null,"abstract":"<div><h3>Background</h3><div>In the year following the U.S. Supreme Court's decision in Dobbs v. Jackson Women's Health Organization to remove federal protection for abortions, new and unprecedented laws were passed related to pregnancy in Texas and elsewhere. Pediatric residents are often the first point of contact for pregnant adolescents. Examining the impact of these laws on pediatric residents is crucial to understanding gaps and promoting quality patient care in this new political landscape.</div></div><div><h3>Methods</h3><div>Pediatric residents were randomly selected from a Texas pediatric residency program and invited for a virtual, semi-structured, one-to-one interview with a trained study investigator between August and October 2024. Interviews explored residents' experience providing healthcare to pregnant patients and knowledge of current laws governing these interactions in Texas. All interviews were recorded, transcribed, and independently conducted using an inductive coding approach by two investigators. Themes were generated using iterative thematic analysis.</div></div><div><h3>Results</h3><div>Participants (n=11) included 4 third-year pediatric residents and 7 second-year pediatric residents. Inductive coding generated 34 codes consolidated into 8 themes. Data showed fear of discussing abortion was universal among residents with concerns around rules for notifying patients’ parents, and legal ramifications of documentation. Residents also discussed the emotional and moral burden of being limited in the care they can provide and awareness of the unequal impact of restrictive laws on low-income patients. Misconceptions of laws related to reproductive health care were pervasive among residents who were often informed by more senior physicians or non-academic online resources, with most residents assuming stricter versions of current policies. Overall, residents were enthusiastic about learning to care for pregnant patients and desired more clarification in their training.</div></div><div><h3>Conclusions</h3><div>Study findings show high levels of fear discussing abortion and common misconceptions about abortion policy among pediatric residents caring for pregnant adolescents in Texas. Given radical shifts in the U.S. policy environment, new pregnancy-focused training materials are necessary to ensure trainees feel confident caring for this patient population. Increased resident training is especially important in restrictive legal environments like Texas to prevent trainees from “over-implementing” state abortion policies and placing additional restrictions on patients' access to reproductive health services.</div></div>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":"38 2","pages":"Page 233"},"PeriodicalIF":1.7,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
26. Delayed hypersensitivity reaction to Mirena IUD
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-28 DOI: 10.1016/j.jpag.2025.01.059
Eva Chorna Sherman, Monique Regard

Background

Immune-mediated hypersensitivity reactions have been documented in response to endogenous and exogenous progesterone including the levonorgestrel-containing intrauterine device (IUD), with reactions ranging from urticaria to angioedema and anaphylaxis. Typically, reactions to progesterone have been described as acute or chronic in onset with long lasting symptoms. This case will discuss a unique timeline of onset and symptom progression.

Case

A 22-year-old patient presented to the ED with 3 days of worsening itching, burning and tingling. The patient had been seen that morning by her Pediatric Adolescent Gynecologist (PAG) for follow up 6.5 weeks after placement of a Mirena IUD for long-term management of endometriosis. She had been on the oral contraceptive pill Lo Loestrin for over one year, while IUD in situ. PAG decided not to remove IUD since symptoms were still mild, pending input from allergist for evaluation of alternate causes. Symptoms progressed throughout the day to include upper and lower extremity swelling bringing her to the ED, at which time she was discharged with antihistamines. However, swelling continued to worsen and she returned to ED 24 hours later. Physical exam was notable for maculopapular erythema and edema to the face palms and soles of feet. IUD was removed immediately, and patient was treated with Solu-Medrol and Benadryl with symptomatic improvement. She was discharged to home with prednisone, and symptoms resolved over the next 3 days. Follow up with outpatient immunologist determined case to be consistent with delayed hypersensitivity reaction in response to exogenous progesterone from the IUD. She has had no recurrence of symptoms since the IUD was removed.

Comments

While there is no absolute confirmation that the IUD was the sole cause of her acute pruritus and edema, there is a strong correlation between symptom onset and resolution relative to IUD insertion and removal. Documented cases of hypersensitive reactions in response to progesterone exposure have a timeline that generally fall within 2 categories. First is acute symptom onset appearing within several days of IUD insertion or second, chronic symptoms appearing months later and lasting years. This case illustrates an unusual timeline of progesterone-based IUD reaction with acute onset of symptoms 6 weeks after insertion progression within days to severe symptoms. Recognizing that an allergic reaction to a Mirena IUD can occur in this timeline and escalate to potentially life-threatening anaphylaxis is crucial since removing the Mirena IUD allergen is the cure.
{"title":"26. Delayed hypersensitivity reaction to Mirena IUD","authors":"Eva Chorna Sherman,&nbsp;Monique Regard","doi":"10.1016/j.jpag.2025.01.059","DOIUrl":"10.1016/j.jpag.2025.01.059","url":null,"abstract":"<div><h3>Background</h3><div>Immune-mediated hypersensitivity reactions have been documented in response to endogenous and exogenous progesterone including the levonorgestrel-containing intrauterine device (IUD), with reactions ranging from urticaria to angioedema and anaphylaxis. Typically, reactions to progesterone have been described as acute or chronic in onset with long lasting symptoms. This case will discuss a unique timeline of onset and symptom progression.</div></div><div><h3>Case</h3><div>A 22-year-old patient presented to the ED with 3 days of worsening itching, burning and tingling. The patient had been seen that morning by her Pediatric Adolescent Gynecologist (PAG) for follow up 6.5 weeks after placement of a Mirena IUD for long-term management of endometriosis. She had been on the oral contraceptive pill Lo Loestrin for over one year, while IUD in situ. PAG decided not to remove IUD since symptoms were still mild, pending input from allergist for evaluation of alternate causes. Symptoms progressed throughout the day to include upper and lower extremity swelling bringing her to the ED, at which time she was discharged with antihistamines. However, swelling continued to worsen and she returned to ED 24 hours later. Physical exam was notable for maculopapular erythema and edema to the face palms and soles of feet. IUD was removed immediately, and patient was treated with Solu-Medrol and Benadryl with symptomatic improvement. She was discharged to home with prednisone, and symptoms resolved over the next 3 days. Follow up with outpatient immunologist determined case to be consistent with delayed hypersensitivity reaction in response to exogenous progesterone from the IUD. She has had no recurrence of symptoms since the IUD was removed.</div></div><div><h3>Comments</h3><div>While there is no absolute confirmation that the IUD was the sole cause of her acute pruritus and edema, there is a strong correlation between symptom onset and resolution relative to IUD insertion and removal. Documented cases of hypersensitive reactions in response to progesterone exposure have a timeline that generally fall within 2 categories. First is acute symptom onset appearing within several days of IUD insertion or second, chronic symptoms appearing months later and lasting years. This case illustrates an unusual timeline of progesterone-based IUD reaction with acute onset of symptoms 6 weeks after insertion progression within days to severe symptoms. Recognizing that an allergic reaction to a Mirena IUD can occur in this timeline and escalate to potentially life-threatening anaphylaxis is crucial since removing the Mirena IUD allergen is the cure.</div></div>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":"38 2","pages":"Pages 242-243"},"PeriodicalIF":1.7,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
1. A case of obstructed hemivagina and ipsilateral renal anomaly complicated by pelvic abscess in an adolescent patient with history of cloacal anomaly
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-28 DOI: 10.1016/j.jpag.2025.01.034
Roselyn Terrazos-Moreno, Anne Smith

Background

An association between anorectal malformations and mullerian anomalies has been established in the literature. We present a unique case of a patient with cloacal anomaly and obstructed hemivagina and ipsilateral renal anomaly (OHIVRA) complicated by a pelvic abscess.

Case

An 18-year-old female with cloacal anomaly and history of genitourinary reconstruction at 3 months old and solitary right kidney presented to the emergency room with left lower quadrant pain and constipation. Ultrasound showed a mass on her left ovary, and she was referred to gynecology. In her workup, MRI found didelphys uterus and left hematocolpos. The patient had no prior knowledge of this anatomy and operative reports from her genitourinary surgeries in Italy reported a normal uterus and vagina. The patient was scheduled for excision of vaginal septum and drainage of hematocolpos. The patient returned to the emergency room 1 week before surgery with worsening pelvic pain. Mild leukocytosis was present, but there was low suspicion for infection due to negative urine cultures and her prophylactic antibiotic regimen. She was discharged in a day. During scheduled surgery, a rectovaginal exam revealed a 2-3 cm palpable fluid collection between the right hemivagina and rectum. Exploration of the right hemivagina revealed purulent fluid. The abscess was drained, intraoperative antibiotics were given, and augmentin was prescribed at discharge. One month later, the patient returned to the emergency room due to septic shock secondary to right-sided pyosalpinx. Infectious disease was involved early in care due to complexity of pelvic anatomy and renal history. An abscess drainage tube was placed by interventional radiology. The patient was given intravenous meropenem and doxycycline which was narrowed to oral amoxicillin and flagyl. MRI 3 months later showed a decrease in the size of the abscess. In follow up visits the patient denied fever or pelvic pain that was present before drainage of abscess.

Comments

Coexisting cloacal and renal anomalies should prompt consideration for OHIVRA early on. Normal uterine anatomy should not be assumed based on pre-pubertal records in patients with other anomalies. Re-evaluation at a later age may be necessary if the patient is presenting with menstrual irregularities and pelvic pain. Additionally, surgeons should consider pelvic abscess as a possible intraoperative complication in OHIVRA. The complex anatomy may lend to microperforations that allow a path for bacterial migration from the external environment to the obstructed vagina, as well as between the two vaginas.
{"title":"1. A case of obstructed hemivagina and ipsilateral renal anomaly complicated by pelvic abscess in an adolescent patient with history of cloacal anomaly","authors":"Roselyn Terrazos-Moreno,&nbsp;Anne Smith","doi":"10.1016/j.jpag.2025.01.034","DOIUrl":"10.1016/j.jpag.2025.01.034","url":null,"abstract":"<div><h3>Background</h3><div>An association between anorectal malformations and mullerian anomalies has been established in the literature. We present a unique case of a patient with cloacal anomaly and obstructed hemivagina and ipsilateral renal anomaly (OHIVRA) complicated by a pelvic abscess.</div></div><div><h3>Case</h3><div>An 18-year-old female with cloacal anomaly and history of genitourinary reconstruction at 3 months old and solitary right kidney presented to the emergency room with left lower quadrant pain and constipation. Ultrasound showed a mass on her left ovary, and she was referred to gynecology. In her workup, MRI found didelphys uterus and left hematocolpos. The patient had no prior knowledge of this anatomy and operative reports from her genitourinary surgeries in Italy reported a normal uterus and vagina. The patient was scheduled for excision of vaginal septum and drainage of hematocolpos. The patient returned to the emergency room 1 week before surgery with worsening pelvic pain. Mild leukocytosis was present, but there was low suspicion for infection due to negative urine cultures and her prophylactic antibiotic regimen. She was discharged in a day. During scheduled surgery, a rectovaginal exam revealed a 2-3 cm palpable fluid collection between the right hemivagina and rectum. Exploration of the right hemivagina revealed purulent fluid. The abscess was drained, intraoperative antibiotics were given, and augmentin was prescribed at discharge. One month later, the patient returned to the emergency room due to septic shock secondary to right-sided pyosalpinx. Infectious disease was involved early in care due to complexity of pelvic anatomy and renal history. An abscess drainage tube was placed by interventional radiology. The patient was given intravenous meropenem and doxycycline which was narrowed to oral amoxicillin and flagyl. MRI 3 months later showed a decrease in the size of the abscess. In follow up visits the patient denied fever or pelvic pain that was present before drainage of abscess.</div></div><div><h3>Comments</h3><div>Coexisting cloacal and renal anomalies should prompt consideration for OHIVRA early on. Normal uterine anatomy should not be assumed based on pre-pubertal records in patients with other anomalies. Re-evaluation at a later age may be necessary if the patient is presenting with menstrual irregularities and pelvic pain. Additionally, surgeons should consider pelvic abscess as a possible intraoperative complication in OHIVRA. The complex anatomy may lend to microperforations that allow a path for bacterial migration from the external environment to the obstructed vagina, as well as between the two vaginas.</div></div>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":"38 2","pages":"Page 230"},"PeriodicalIF":1.7,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143520012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
16. Assessing Residents’ Knowledge of Dysmenorrhea in Adolescents and Young Adults
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-28 DOI: 10.1016/j.jpag.2025.01.049
Hannah Hayward, Michelle Meglin

Background

Our study sought to better understand residents’ knowledge of diagnosis and treatment of primary and secondary dysmenorrhea in adolescents and young adults and whether that knowledge could be improved by a brief educational intervention.

Methods

Residents in the Obstetrics and Gynecology and Pediatrics programs at the Medical University of South Carolina completed a pre-lecture survey, attended a focused lecture on dysmenorrhea, and completed a post-lecture survey. The average percent correct for the pre- and post-lecture surveys was compared.

Results

Twenty-three residents completed both the pre- and post-lecture surveys. The average score on the pre-lecture survey was 72% and the average score on the post-lecture survey was 92% (p < 0.05). Post-graduate year positively correlated with pre-lecture survey score, with PGY-1 through PGY-4 residents averaging 65%, 72%, 79%, and 82%, respectively, on the pre-lecture survey.

Conclusions

We found that an hour-long lecture resulted in a statistically significant improvement in survey scores, suggesting that a brief educational intervention can improve both comfort with and knowledge of the clinical management of these conditions. We also found that post-graduate year (PGY) positively correlated with pre-test score, suggesting that dysmenorrhea is something residents receive clinical exposure to during training and emphasizing the need for foundational education during resident didactics.
{"title":"16. Assessing Residents’ Knowledge of Dysmenorrhea in Adolescents and Young Adults","authors":"Hannah Hayward,&nbsp;Michelle Meglin","doi":"10.1016/j.jpag.2025.01.049","DOIUrl":"10.1016/j.jpag.2025.01.049","url":null,"abstract":"<div><h3>Background</h3><div>Our study sought to better understand residents’ knowledge of diagnosis and treatment of primary and secondary dysmenorrhea in adolescents and young adults and whether that knowledge could be improved by a brief educational intervention.</div></div><div><h3>Methods</h3><div>Residents in the Obstetrics and Gynecology and Pediatrics programs at the Medical University of South Carolina completed a pre-lecture survey, attended a focused lecture on dysmenorrhea, and completed a post-lecture survey. The average percent correct for the pre- and post-lecture surveys was compared.</div></div><div><h3>Results</h3><div>Twenty-three residents completed both the pre- and post-lecture surveys. The average score on the pre-lecture survey was 72% and the average score on the post-lecture survey was 92% (p &lt; 0.05). Post-graduate year positively correlated with pre-lecture survey score, with PGY-1 through PGY-4 residents averaging 65%, 72%, 79%, and 82%, respectively, on the pre-lecture survey.</div></div><div><h3>Conclusions</h3><div>We found that an hour-long lecture resulted in a statistically significant improvement in survey scores, suggesting that a brief educational intervention can improve both comfort with and knowledge of the clinical management of these conditions. We also found that post-graduate year (PGY) positively correlated with pre-test score, suggesting that dysmenorrhea is something residents receive clinical exposure to during training and emphasizing the need for foundational education during resident didactics.</div></div>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":"38 2","pages":"Page 237"},"PeriodicalIF":1.7,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143520017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimizing Contraceptive Counseling for Adolescents: Meeting the Needs of Undecided Patients
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-28 DOI: 10.1016/j.jpag.2024.10.001
Khairiyah Khadijah , Rizky Andana Pohan , Ririn Dwi Astuti , Putri Bunga Aisyah Pohan , Sesilianus Fau , Muhammad Putra Dinata Saragi , Erfan Ramadhani
{"title":"Optimizing Contraceptive Counseling for Adolescents: Meeting the Needs of Undecided Patients","authors":"Khairiyah Khadijah ,&nbsp;Rizky Andana Pohan ,&nbsp;Ririn Dwi Astuti ,&nbsp;Putri Bunga Aisyah Pohan ,&nbsp;Sesilianus Fau ,&nbsp;Muhammad Putra Dinata Saragi ,&nbsp;Erfan Ramadhani","doi":"10.1016/j.jpag.2024.10.001","DOIUrl":"10.1016/j.jpag.2024.10.001","url":null,"abstract":"","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":"38 2","pages":"Pages 213-214"},"PeriodicalIF":1.7,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143520094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
10. Addressing Adolescent Sexual and Reproductive Health Needs during Inpatient Psychiatric Admission
IF 1.7 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2025-02-28 DOI: 10.1016/j.jpag.2025.01.043
Radhika Amin, Paris Stowers, Shandhini Raidoo

Background

Both adolescents and people with psychiatric disorders are disproportionately affected by adverse sexual and reproductive health (SRH) outcomes but little is known about their specific SRH needs. Inpatient settings provide a unique opportunity to address SRH concerns because adolescents often miss out on school-based SRH education when hospitalized. The primary objective was to identify adolescent patients’ perceptions of the SRH services they are receiving at an inpatient adolescent psychiatric unit in Honolulu, Hawai'i.

Methods

The Queen's Medical Center Institutional Review Board (IRB; protocol RA-2020-26) approved this qualitative research study. We identified patients aged 14-19 admitted to the inpatient psychiatric unit who had received SRH care during their current admission. Permission to approach patients was obtained from the patient's primary attending and written informed consent was obtained at the time of each interview. We conducted semi-structured interviews with participants about their experiences with SRH care until thematic saturation was reached. The interviews were recorded, transcribed, and analyzed through the iterative process of content analysis to identify themes and relationships between ideas.

Results

Eleven adolescents were interviewed from 2022-2023. We collected patient demographics and clinical characteristics, including race, diagnosis, and type of SRH services received. Six themes were identified: 1) patients value healthcare providers’ experience and expertise, 2) inpatient hospitalization is an appropriate time to address SRH needs, 3) interaction between mental health and decision making for SRH choices is complex, 4) access to SRH care in the outpatient setting is variable and dependent on social factors, 5) female family members play a key role in SRH care, and 6) most patients received SRH education in school and deemed school is an appropriate place to learn this information despite some negative aspects of the school-based setting.

Conclusions

This study revealed the important role of healthcare providers in the inpatient setting and female family members in the outpatient setting in supporting adolescents with psychiatric disorders and their SRH needs. Healthcare providers are accessible to adolescents during an inpatient admission while access in the outpatient setting can be highly dependent on social support factors. The inpatient setting is a valuable place to address adolescents’ SRH needs and should be linked to outpatient resources for continuity of care following hospital discharge.
背景青少年和精神疾病患者受到不良性健康和生殖健康(SRH)结果的影响尤为严重,但人们对他们在性健康和生殖健康方面的具体需求却知之甚少。住院环境为解决性健康和生殖健康问题提供了一个独特的机会,因为青少年住院时往往错过了学校的性健康和生殖健康教育。本研究的主要目的是确定青少年患者对他们在夏威夷檀香山青少年精神病住院部所接受的性健康和生殖健康服务的看法。我们确定了入住精神科住院病房的 14-19 岁患者,这些患者在本次入院期间接受了性健康和生殖健康护理。我们从患者的主治医生处获得了与患者接触的许可,并在每次访谈时获得了患者的书面知情同意。我们对参与者进行了半结构化访谈,了解他们在性健康和生殖健康护理方面的经历,直至达到主题饱和。我们对访谈进行了记录、转录,并通过内容分析的迭代过程进行分析,以确定主题和观点之间的关系。我们收集了患者的人口统计学特征和临床特征,包括种族、诊断和所接受的性健康和生殖健康服务类型。我们确定了六个主题:1)患者重视医疗服务提供者的经验和专业知识;2)住院治疗是满足性健康和生殖健康需求的适当时机;3)心理健康与性健康和生殖健康选择决策之间的相互作用非常复杂;4)在门诊环境中获得性健康和生殖健康护理的机会是可变的,并取决于社会因素;5)女性家庭成员在性健康和生殖健康护理中发挥着关键作用;6)大多数患者在学校接受了性健康和生殖健康教育,并认为学校是了解这些信息的适当场所,尽管学校环境存在一些负面因素。结论 本研究揭示了住院环境中的医疗服务提供者和门诊环境中的女性家庭成员在支持患有精神障碍的青少年及其性健康和生殖健康需求方面所发挥的重要作用。在住院期间,青少年可以接触到医疗服务提供者,而在门诊环境中,能否接触到医疗服务提供者则在很大程度上取决于社会支持因素。住院环境是满足青少年性健康和生殖健康需求的重要场所,应将住院环境与门诊资源联系起来,以保证出院后护理的连续性。
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引用次数: 0
期刊
Journal of pediatric and adolescent gynecology
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