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Hidradenitis Suppurativa in the Pediatric and Adolescent Population 儿童和青少年人群中的化脓性汗腺炎。
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 Epub Date: 2025-09-30 DOI: 10.1016/j.jpag.2025.09.007
Natalie Hickerson MD , Hadar Lev-Tov MD, MAS , Sara Danker MD , Judith Simms-Cendan MD
Hidradenitis suppurativa (HS) is a complex disease that manifests with nodules, abscesses, and tunnels in the intertriginous regions of the body. Symptoms often begin after adrenarche and may progress to severe disease with draining tunnels and permanent scars, leading to a significant reduction in quality of life and mental health. Diagnostic delays are common, increasing the risk of disease progression. Timely diagnosis and effective management are essential to the prevention of complications in the pediatric and adolescent population. This review will cover the currently available information on pathophysiology, risk factors, presentation, diagnosis, and management of HS in this population.
化脓性汗腺炎(HS)是一种复杂的疾病,表现为结节,脓肿和隧道在身体的三角间区。症状通常在肾上腺素激增后开始,并可能发展为严重的疾病,并伴有引流隧道和永久性疤痕,导致生活质量和心理健康的显著下降。诊断延误是常见的,增加了疾病进展的风险。及时诊断和有效管理对于预防儿科和青少年人群的并发症至关重要。这篇综述将涵盖目前可获得的关于这一人群中HS的病理生理、危险因素、表现、诊断和管理的信息。
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引用次数: 0
From Avoidance to Empowerment: Coping Strategies in Women With Müllerian agenesis (MRKH) After McIndoe Reconstruction: A Descriptive Phenomenological Study 从回避到赋权:麦氏重建后女性<s:1>勒氏发育不全(MRKH)的应对策略——一项描述性现象学研究。
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 Epub Date: 2025-10-26 DOI: 10.1016/j.jpag.2025.10.013
Perihan Güner PhD, RN , Tuğba Ulukaya RN

Study Objective

To explore coping strategies among women with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome following McIndoe vaginal reconstruction, focusing on how they adapt emotionally, cognitively, relationally, and spiritually.

Methods

A descriptive phenomenological study was conducted at a tertiary university hospital in Türkiye. Ten women with MRKH syndrome who underwent McIndoe vaginoplasty were recruited. Data were collected through semi-structured, in-depth interviews and analyzed using Colaizzi’s seven-step framework. Reporting adhered to the COREQ checklist.

Results

Six overarching themes and twelve subthemes were identified:1 managing silence and avoidance,2 reframing and positive reappraisal,3 spiritual coping,4 relational dynamics of support and stigma,5 disclosure dilemmas, and6 pathways to empowerment. Coping strategies were dynamic, shifting from avoidance to eventual empowerment, and were shaped by family dynamics, cultural norms, spirituality, and relational contexts.

Conclusion

Coping following McIndoe reconstruction extends beyond surgical success to encompass psychological adjustment, relational support, and the creation of cultural and spiritual meaning. Holistic interventions-including psychoeducation, culturally sensitive counselling, family- and couple-based approaches, and structured peer networks-may strengthen resilience and promote well-being in this population.
研究目的:探讨McIndoe阴道重建术后MRKH (mayer - rokitansky - k ster- hauser)综合征女性的应对策略,重点关注她们在情感、认知、关系和精神方面的适应情况。方法:采用描述性现象学研究方法在浙江省某三级大学附属医院进行。10名患有MRKH综合征的女性接受了McIndoe阴道成形术。通过半结构化的深度访谈收集数据,并使用Colaizzi的七步框架进行分析。报告遵循COREQ检查表。结果:确定了6个总体主题和12个副主题:(1)管理沉默和回避,(2)重构和积极的重新评价,(3)精神应对,(4)支持和耻辱的关系动力学,(5)披露困境,(6)赋权途径。应对策略是动态的,从回避到最终的授权,并由家庭动态、文化规范、精神和关系背景形成。结论:McIndoe重建术后的应对不仅仅是手术成功,还包括心理调整、关系支持以及文化和精神意义的创造。整体干预措施——包括心理教育、文化敏感咨询、以家庭和夫妻为基础的方法,以及结构化的同伴网络——可能会增强这一人群的适应力,促进他们的福祉。
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引用次数: 0
Providing Contraception to Trans Youth: A Qualitative Study Investigating the Acceptability of Subcutaneous Depot Medroxyprogesterone Acetate and Prior Experiences With Contraceptive Counseling 向跨性别青年提供避孕:一项调查DMPA-SC可接受性和先前避孕咨询经验的定性研究。
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 Epub Date: 2025-10-04 DOI: 10.1016/j.jpag.2025.09.008
Nicholas R.W. Cleland MD , Charlie E. Graves BS , Lauren M. Reade BS , Natalie J. Nokoff MD, MS , Ryan P. O’Connell MS, CHES , Nancy Z. Fang MD, MS

Introduction

The transgender and gender diverse (TGD) population continues to face unmet healthcare needs, especially when pertaining to sexual and reproductive health (SRH). When receiving care, TGD individuals may face discrimination or receive care that does not affirm their gender identity or is rooted in cisgender, heteronormative assumptions. This qualitative study sought to understand the experiences and perspectives of TGD youth surrounding contraceptive use and counseling, and investigate acceptability of self-administered subcutaneous depot medroxyprogesterone acetate (DMPA-SC).

Methods

We conducted semi-structured focus groups and individual interviews to understand what drove initiation and discontinuation of contraceptives, specifically DMPA-SC. We recruited 35 TGD individuals assigned female at birth, with median (IQR) age of 17.5 (2.75) years. Twenty-one participants completed focus groups and 10 completed individual interviews. Interviews were conducted virtually and analyzed using rapid thematic analysis.

Results

We identified 4 themes: (1) Dysmenorrhea and dysphoria associated with menses that were alleviated by DMPA; (2) DMPA seen as the best method for menstrual suppression; (3) Negative experiences with previous primary care providers (PCPs); the importance of language and a desire for individualized care regarding SRH.

Discussion

The SRH needs of TGD individuals differ from their cisgender counterparts. Historically, the primary endpoint for contraceptive studies focused on preventing pregnancies. Assuming this as the primary goal for TGD individuals can be harmful to the provider-patient relationship and lead to avoidance of care. When providing contraceptives at the intersection of gender identity and sexual orientation, counseling should be tailored towards an individual’s unique SRH needs.
简介:跨性别和性别多样化(TGD)人口继续面临未满足的医疗保健需求,特别是当涉及到性健康和生殖健康(SRH)。在接受护理时,TGD个体可能面临歧视,或接受的护理不肯定其性别认同,或根植于顺性别、异性恋规范的假设。本定性研究旨在了解TGD青年在避孕使用和咨询方面的经验和观点,并调查自我皮下注射醋酸甲羟孕酮(DMPA-SC)的可接受性。方法:我们进行了半结构化的焦点小组和个人访谈,以了解避孕药开始和停止的原因,特别是DMPA-SC。我们招募了35名出生时被指定为女性的TGD个体,中位(IQR)年龄为17.5(2.75)岁。21名参与者完成了焦点小组,10名完成了个人访谈。访谈以虚拟方式进行,并使用快速专题分析进行分析。结果:我们确定了四个主题:(1)DMPA减轻了月经相关的痛经和烦躁;(2)DMPA被认为是抑制月经的最佳方法;(3)与以前的初级保健提供者(pcp)的负面经历;语言的重要性和对性生殖健康个性化护理的渴望。讨论:TGD个体的SRH需求不同于他们的顺性别同伴。从历史上看,避孕研究的主要终点集中在预防怀孕。假设这是TGD个体的主要目标,可能会损害医患关系,并导致逃避护理。当在性别认同和性取向的交叉点提供避孕药具时,咨询应针对个人独特的性健康和生殖健康需求量身定制。
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引用次数: 0
Primary Ovarian Torsion in Pediatric Patients: Is Oophoropexy Still an Option? A 14-Year Single-Center Experience 儿科患者原发性卵巢扭转:卵巢切除术仍然是一种选择吗?14年的单中心体验。
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 Epub Date: 2025-10-17 DOI: 10.1016/j.jpag.2025.10.008
Giacomo Mandarano MD , Filippo Parolini MD , Michele Bosisio MD , Simona Gramaglia MD , Daniela Maria De Previde Prato MD , Giovanni Boroni MD , Claudia Stegher MD , Franco Edoardo Odicino MD , Daniele Alberti MD

Study objective

Pediatric primary ovarian torsion (POT) is a rare condition related to anatomical predispositions and hormonal triggers. The high recurrence rate of laparoscopic ovarian detorsion (LOD) has led to the consideration of primary oophoropexy (OPX). This study aims to investigate OPX indications in POT and evaluate the efficacy of different fixation techniques.

Methods

A retrospective review was conducted on all pediatric patients (1-14 years) with POT treated with LOD or LOD+OPX at our tertiary care center between 2010 and 2024. The sites of fixation were round ligament, ovarian fossa, utero-ovarian ligament, and uterine body. The data collected included demographic, clinical, imaging, surgical, and follow-up results. Statistical analyses were performed to identify factors associated with recurrence and to compare LOD with LOD+OPX.

Results

Eighteen patients (median age 9.4 years) were included in the study. LOD was performed in 56% of cases, while LOD+OPX was performed in 44%. The overall recurrence rate was 44%, with 40% recurrence after LOD and 50% after LOD+OPX (p = 1). Notably, all OPX cases involving the round ligament relapsed (100%), compared to a significantly lower recurrence rate for other OPX sites (20%). Statistical analysis confirmed the round ligament as an inadequate fixation site (P = .027). Follow-up ultrasound revealed normal ovarian morphology in 62% of patients and signs of progressive ovarian atrophy in 38%.

Conclusion

In our experience, POT predominantly occurred in premenarchal patients with hypermobile utero-ovarian ligaments. Given the high POT recurrence rate after LOD, adjunctive OPX effectively reduced the recurrence rate, except when fixation was performed at the round ligament.
研究目的:儿童原发性卵巢扭转(POT)是一种罕见的疾病,与解剖易感性和激素触发有关。腹腔镜卵巢畸形(LOD)的高复发率导致了原发性卵巢畸形(OPX)的考虑。本研究旨在探讨OPX在POT中的适应症,并评估不同固定技术的疗效。方法:对2010年至2024年间我院三级医疗中心所有接受LOD或LOD+OPX治疗的1-14岁小儿POT患者进行回顾性分析。固定部位为圆韧带、卵巢窝、子宫-卵巢韧带和子宫体。收集的数据包括人口统计、临床、影像学、手术和随访结果。进行统计学分析以确定与复发相关的因素,并比较LOD与LOD+OPX。结果:18例患者(中位年龄9.4岁)纳入研究。56%的病例行LOD, 44%的病例行LOD+OPX。总复发率为44%,LOD术后复发率为40%,LOD+OPX术后复发率为50% (p=1)。值得注意的是,所有涉及圆形韧带的OPX病例均复发(100%),而其他OPX部位的复发率明显较低(20%)。统计分析证实圆形韧带是不合适的固定部位(p=0.027)。随访超声显示62%的患者卵巢形态正常,38%的患者卵巢有进行性萎缩的迹象。结论:根据我们的经验,POT主要发生在月经前伴有子宫卵巢韧带过度活动的患者。考虑到LOD后POT的高复发率,除了在圆韧带处进行固定外,辅助OPX有效地降低了复发率。
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引用次数: 0
Adolescents, Abortion, and Reproductive Justice: An Unpostponable Debt 青少年、堕胎和生殖正义:一笔不可推迟的债务。
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 Epub Date: 2025-09-30 DOI: 10.1016/j.jpag.2025.09.015
Marisa Labovsky MD, IFEPAG (FIGIJ President)
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引用次数: 0
Adolescents and Induced Abortions: The Issue Has Not Gone Away 青少年和人工流产:这个问题并没有消失
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 Epub Date: 2026-02-03 DOI: 10.1016/j.jpag.2026.01.010
Paula J. Adams Hillard MD (JPAG Editor-in-Chief)
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引用次数: 0
Responding to Adolescents’ Emotional Needs in Abortion: The Importance of Empathy-Based Counseling and Flexible Choice 回应青少年堕胎的情感需求:移情辅导与灵活选择的重要性
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 Epub Date: 2026-02-03 DOI: 10.1016/j.jpag.2025.07.012
Dony Darma Sagita S.Pd., M.Pd., Kons , Mutiara Felicita Amsal S.Ag., M.Pd. , Ahmad Syaikhu M.Pd , Sari Wardaani Simarmata M.Pd , Della Raymena Jovanka M.Psi , Uliya Khoirun Nisa M.Pd
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引用次数: 0
Beyond PCOS: An Unusual Presentation of Type A Insulin Resistance Syndrome 超越多囊卵巢综合征:A型胰岛素抵抗综合征的不寻常表现。
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 Epub Date: 2025-09-27 DOI: 10.1016/j.jpag.2025.09.013
Maja Cehic MD , Tatjana Milenkovic MD, PhD , Sladjana Todorovic MD , Katarina Mitrovic MD, PhD , Sanja Panic Zaric MD , Dimitrije Cvetkovic MD , Rade Vukovic MD, PhD

Background

Insulin resistance (IR) is commonly seen in adolescent polycystic ovary syndrome (PCOS). However, severe IR with polycystic ovaries in non-obese adolescent girls should prompt suspicion for causes other than typical PCOS.

Case

A 16-year-old normal-weight girl presented with polyuria and polydipsia, along with irregular periods, hirsutism, and acanthosis nigricans. Her clinical presentation, laboratory results and ultrasound findings suggested severe PCOS with type 2 diabetes, but the pronounced degree of IR prompted further investigations. Genetic testing identified a heterozygous deletion in the INSR gene, confirming type A insulin resistance syndrome (TAIRS).

Summary

This case highlights the importance of considering genetic insulin receptor abnormalities in atypical PCOS presentations, especially in non-obese adolescents with severe IR. Early recognition is crucial for appropriate management and genetic counselling.
背景:胰岛素抵抗(Insulin resistance, IR)常见于青春期多囊卵巢综合征(PCOS)。然而,在非肥胖的青春期女孩中,严重的IR伴多囊卵巢应引起对典型多囊卵巢综合征以外原因的怀疑。病例:一名16岁体重正常的女孩,表现为多尿、多饮、月经不规律、多毛、黑棘皮症。她的临床表现,实验室结果和超声检查提示严重的多囊卵巢综合征合并2型糖尿病,但明显的IR程度促使进一步的调查。基因检测发现了INSR基因的杂合缺失,证实了a型胰岛素抵抗综合征(TAIRS)。摘要:本病例强调了考虑遗传性胰岛素受体异常在非典型PCOS表现中的重要性,特别是在患有严重IR的非肥胖青少年中。早期识别对于适当的管理和遗传咨询至关重要。
{"title":"Beyond PCOS: An Unusual Presentation of Type A Insulin Resistance Syndrome","authors":"Maja Cehic MD ,&nbsp;Tatjana Milenkovic MD, PhD ,&nbsp;Sladjana Todorovic MD ,&nbsp;Katarina Mitrovic MD, PhD ,&nbsp;Sanja Panic Zaric MD ,&nbsp;Dimitrije Cvetkovic MD ,&nbsp;Rade Vukovic MD, PhD","doi":"10.1016/j.jpag.2025.09.013","DOIUrl":"10.1016/j.jpag.2025.09.013","url":null,"abstract":"<div><h3>Background</h3><div>Insulin resistance (IR) is commonly seen in adolescent polycystic ovary syndrome (PCOS). However, severe IR with polycystic ovaries in non-obese adolescent girls should prompt suspicion for causes other than typical PCOS.</div></div><div><h3>Case</h3><div>A 16-year-old normal-weight girl presented with polyuria and polydipsia, along with irregular periods, hirsutism, and acanthosis nigricans. Her clinical presentation, laboratory results and ultrasound findings suggested severe PCOS with type 2 diabetes, but the pronounced degree of IR prompted further investigations. Genetic testing identified a heterozygous deletion in the INSR gene, confirming type A insulin resistance syndrome (TAIRS).</div></div><div><h3>Summary</h3><div>This case highlights the importance of considering genetic insulin receptor abnormalities in atypical PCOS presentations, especially in non-obese adolescents with severe IR. Early recognition is crucial for appropriate management and genetic counselling.</div></div>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":"39 1","pages":"Pages 131-134"},"PeriodicalIF":1.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contraception-Related Posts from Adolescents, Young Adults, and Caregivers on Reddit: A Qualitative Content Analysis. Reddit上来自青少年、年轻人和看护者的与避孕有关的帖子:一项定性内容分析。
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-01-29 DOI: 10.1016/j.jpag.2026.01.004
Cambray Smith, Christina Cobos, Renee Odom-Konja, Elizabeth Pleasants, Sneha A Makhijani, Eleanor Hummel, Eliza Dolgins, Layla Leo, Rolando Rodriguez, Betsy Sleath, Christopher M Shea, Melissa Gilkey, Bianca A Allison, Leah Frerichs

Study objective: To summarize contraceptive information shared and sought by adolescents and young adults (AYAs) and caregivers on Reddit.

Methods: Posts were collected from 8 subreddits (June 2022 to September 2024) using contraception-related keywords. Eligible posts were in English and authored by self-identifying AYAs (<26 years) or caregivers; comments from 10% of posts were included. We used hybrid inductive-deductive qualitative content analysis to characterize each post's primary purpose and to summarize common methods, side effects, medical and access questions, confusion/misconceptions, and sentiments.

Results: Of 607 posts, 297 met inclusion. Over half were authored by teens (<20 years, 59%), followed by young adults (32%) and caregivers (10%). The pill (47%) and intrauterine devices (25%) were most discussed. Common side effects included menstrual changes (36%) and mood/mental health (29%). Teens (n = 174) frequently discussed condoms (23%) and emergency contraception (12%). Teens and young adults (n = 268) shared sex/contraception education (13%) and opinions on contraceptive rights/behaviors (12%). They sought medical/behavioral advice (38%), contraceptive knowledge (15%), pregnancy scare advice (11%), and communication/access advice (9%). Caregivers (n = 29) sought method recommendations (38%), shared moral/ethical concerns (35%), and sought knowledge (17%) or communication advice (10%). Overall (N = 297), 15% contained misconceptions and 16% featured antihormonal sentiment. Few expressed positive emotions (10%) or trust (10%), while many conveyed negative emotions (60%) or mistrust (28%).

Conclusion: Reddit posts about contraception from AYAs and caregivers cover diverse topics, are often negative, and sometimes feature misconceptions that may influence decision-making. Clinicians should address online contraceptive information during counseling to better respond to patient concerns.

研究目的:总结青少年和年轻人(AYAs)及其护理人员在Reddit上分享和寻求的避孕信息。方法:从8个reddit子版块(2022年6月- 2024年9月)收集与避孕相关的关键词帖子。符合条件的帖子均为英文,由自我认同的AYAs撰写(结果:607篇帖子中,297篇符合纳入标准。超过一半的帖子是由青少年撰写的(结论:Reddit上关于AYAs和护理人员避孕的帖子涵盖了各种各样的主题,通常是消极的,有时还会有可能影响决策的误解。临床医生应在咨询过程中处理在线避孕信息,以更好地回应患者的担忧。
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引用次数: 0
Changes in HPV vaccine uptake following the COVID Vaccine. COVID疫苗接种后HPV疫苗摄取的变化。
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-01-29 DOI: 10.1016/j.jpag.2026.01.045
Stephanie Harlow, Elizabeth Anderson, Ilana Cass

Purpose: Historically, the Human Papilloma Virus (HPV) vaccine has been the subject of vaccine hesitancy. In 2020, the introduction of a COVID-19 vaccine incited a new wave of vaccine hesitancy. We investigated whether introducing the COVID vaccine correlated with changes in HPV vaccine initiation compared to Tdap in a large New England health system.

Methods: Initial doses only of HPV as well as first recorded doses of the Tdap vaccine administered to individuals ages 9 to 18 between March 2019 and May 2023 were analyzed. Linear trends and per-day rates of each vaccine were assessed in three periods: prior to the pandemic (3/19-2/20); during the pandemic (3/20-5/21); and post-COVID vaccine (5/21-5/23), with a secondary analysis performed to account for seasonality. Daily vaccination rates were stratified by sex and population density (urban versus rural).

Results: Records from 15,696 patients who received 10,502 HPV initiation vaccines and 10,282 Tdap vaccines were analyzed. No difference was noted in HPV initiation rates during the pandemic (7.05 vs. 7.30, p=0.203), though a significant decrease was noted post-vaccine compared to pre-pandemic (7.05 vs. 6.63, p=0.011).This post-vaccine decrease was driven primarily by the male (3.68 vs. 3.43, p=0.035) and urban (3.48 vs. 2.73, p<0.001) populations. Tdap rates were unchanged during the pandemic (6.60 vs. 6.34, p=0.148), but increased post-vaccine (6.60 vs. 7.11, =0.003).

Discussion: HPV initiation rates declined following the introduction of the COVID vaccine in a large health system in New England, driven mostly by a decline among males and the urban population.

目的:历史上,人乳头瘤病毒(HPV)疫苗一直是疫苗犹豫的主题。2020年,COVID-19疫苗的推出引发了新一轮对疫苗的犹豫。我们调查了在新英格兰大型卫生系统中,与Tdap相比,引入COVID疫苗是否与HPV疫苗启动变化相关。方法:分析2019年3月至2023年5月期间9至18岁个体仅接种HPV疫苗的初始剂量以及首次记录的Tdap疫苗剂量。在三个时期评估了每种疫苗的线性趋势和每日接种率:大流行之前(3月19日至2月20日);大流行期间(3/20-5/21);和covid后疫苗(5/21-5/23),并进行二次分析以考虑季节性。每日疫苗接种率按性别和人口密度(城市与农村)分层。结果:分析了15696例接种了10502支HPV起始疫苗和10282支Tdap疫苗的记录。在大流行期间,HPV起始率没有差异(7.05 vs. 7.30, p=0.203),尽管与大流行前相比,接种疫苗后显着降低(7.05 vs. 6.63, p=0.011)。这种疫苗接种后的下降主要是由男性(3.68 vs. 3.43, p=0.035)和城市(3.48 vs. 2.73, p)驱动的。讨论:在新英格兰的一个大型卫生系统引入COVID疫苗后,HPV起始率下降,主要是由于男性和城市人口的下降。
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引用次数: 0
期刊
Journal of pediatric and adolescent gynecology
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