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The superficial peroneal neurocutaneous flap: a cadaveric study. 腓浅神经皮瓣:尸体研究。
IF 1.2 4区 医学 Q3 ORTHOPEDICS Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2023.2168273
Thepparat Kanchanathepsak, Katanyata Kunsook, Wasit Panoinont, Chinnawut Suriyonplengsaeng, Sorasak Suppaphol, Ittirat Watcharananan, Panithan Tuntiyatorn, Tulyapruek Tawonsawatruk

Soft tissue defects around the ankle are common and must be covered with thin and pliable flaps. A regional flap, particularly from the dorsum of the foot was considered ideal. A neurocutaneous flap, based on the superficial peroneal nerve (SPN) and its branches was designed as a proximally based flap via cadaveric dissection. This study aimed to demonstrate the vascularity and characteristics of the superficial peroneal neurocutaneous (SPNC) flap. The SPNC flap was created in 11 lower limbs (seven cadavers) using a proximally based design. The skin flap was dissected at the dorsum of the foot, followed by injection of diluted methylene blue through the anterior tibial artery, to visualize the vascularity. The flap pedicle above the anterior ankle joint line was dissected along the SPN for anatomical study of perforating branches, paraneural vessels, and flap territory. The mean distances of the most proximal perforating branches were 1.51 ± 1.48 cm from the anterior ankle joint line, and 5.12 ± 1.78 cm from the lateral malleolus. The mean distances of the most distal perforating branches were 2.75 ± 1.54 cm from the anterior ankle joint line, and 5.90 ± 1.81 cm from the lateral malleolus. The mean number of perforating branches was 3.73 ± 1.49. The mean flap territories were 5.51 ± 0.59 cm in length, and 7.15 ± 0.64 cm in width. The SPNC flap is an alternative method for soft tissue reconstruction around the ankle with a proximally based flap design. The antegrade flow has been shown to offer effective vascularity in flaps prepared via cadaveric dissection.

踝关节周围的软组织缺损是常见的,必须用薄而柔韧的皮瓣覆盖。局部皮瓣,特别是足背皮瓣被认为是理想的。以腓浅神经(SPN)及其分支为基础,通过尸体解剖设计近端皮瓣。本研究旨在展示腓浅神经皮(SPNC)皮瓣的血管性和特征。采用近端为基础的设计在11条下肢(7具尸体)上创建SPNC皮瓣。在足背处解剖皮瓣,然后通过胫骨前动脉注射稀释亚甲基蓝,以观察血管分布。沿SPN解剖踝关节前线以上皮瓣蒂,解剖研究穿支、神经旁血管和皮瓣范围。最近穿支距踝关节前线平均距离1.51±1.48 cm,距外踝平均距离5.12±1.78 cm。最远穿支距踝关节前线平均距离为2.75±1.54 cm,距外踝平均距离为5.90±1.81 cm。平均穿枝数为3.73±1.49根。皮瓣平均长度为5.51±0.59 cm,宽度为7.15±0.64 cm。SPNC皮瓣是一种基于近端皮瓣设计的踝关节周围软组织重建的替代方法。通过尸体解剖制备的皮瓣显示出顺行血流提供有效的血管。
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引用次数: 0
Topography of the deep branch of the ulnar nerve between genders: a cadaveric study with potential clinical implications. 尺神经深支的地形在两性之间:具有潜在临床意义的尸体研究。
IF 1.2 4区 医学 Q3 ORTHOPEDICS Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2022.2032103
Alfio Luca Costa, Konstantinos Natsis, Marco Romeo, Maria Piagkou, Franco Bassetto, Cesare Tiengo, Bruno Battiston, Paolo Titolo, Nikolaos Papadopulos, Michele Rosario Colonna
Abstract The lack of meticulous knowledge concerning the topographical anatomy of the deep branch of the ulnar nerve (DUN) may pose difficulties, leading to a delay or a misdiagnosis of a DUN injury. Identification of the DUN is quite difficult without precise anatomical landmarks as reference points. The current study investigates the topography of the DUN between genders, taking as a reference point a well-known landmark, the Kaplan line, used in hand surgery for carpal tunnel release. Twenty-two (15 males and 7 female) fresh frozen adult cadaveric hands were dissected by using magnifying loupes (3.5 and 5.0 x). We marked values proximal to the Kaplan line as positive (+), while we marked distal ones as negative (-). The mean distance DUN–Kaplan line was 1.69 ± 4.45 mm. In male hands, the mean distance was 4.17 ± 1.88 mm, distal to the Kaplan line, while in females, the mean distance was −4.92 ± 0.69 mm proximal to the Kaplan line. Gender dimorphism was detected, with higher statistically significant values in male hands (p = 0.001). Cadaveric studies of the DUN topography, course, and distribution pattern are uncommon. The current study provides an accurate description of the DUN topography, taking the Kaplan line as a reference point, emphasizing gender differences. The DUN is located distally in males and proximally in females. Knowledge of these predictable anatomical relations may help hand surgeons intraoperatively when dealing with a DUN lesion, because of hand trauma or during the decompression of the DUN.
缺乏对尺神经深支(DUN)的地形解剖的细致了解可能会造成困难,导致DUN损伤的延误或误诊。如果没有精确的解剖标志作为参考点,识别DUN是相当困难的。目前的研究调查了不同性别间DUN的地形,以卡普兰线作为参考点,卡普兰线在手部手术中用于腕管释放。我们用放大镜(3.5倍和5.0倍)解剖了22只(15男7女)新鲜冷冻成人尸体的手。我们将卡普兰线近端标记为阳性(+),将远端标记为阴性(-)。dunp - kaplan线平均距离为1.69±4.45 mm。男性手距Kaplan线远端平均距离为4.17±1.88 mm,女性手距Kaplan线近端平均距离为-4.92±0.69 mm。性别二态性被检测到,男性的手具有更高的统计学意义(p = 0.001)。对DUN地形、病程和分布模式的尸体研究并不常见。目前的研究以卡普兰线为参考点,对DUN地形进行了准确的描述,强调了性别差异。DUN位于男性的远端,女性的近端。了解这些可预测的解剖关系可以帮助手外科医生在术中处理由于手部创伤或在DUN减压过程中造成的DUN病变。
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引用次数: 0
The effect of implant loss after immediate breast reconstruction on patient satisfaction with outcome and quality of life after five years - a case-control study. 一项病例对照研究:即刻乳房再造术后植入物丢失对患者5年后预后和生活质量满意度的影响。
IF 1.2 4区 医学 Q3 ORTHOPEDICS Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2022.2061501
Linn Weick, Carolina Lunde, Emma Hansson

Several advantages have been suggested for immediate breast reconstruction (IBR); however, there is little scientific high-quality evidence confirming those advantages. Disadvantages of IBR, compared to delayed breast reconstruction (DBR), include an increased risk for complications, such as implant loss (prevalence 5-10% vs. 1%). Little is known on how women experience implant loss and how it affects patients' long-term satisfaction and quality of life (QoL). The primary aim of our study was to compare patient satisfaction and QoL of women with implant loss after IBR, with that of women with a successful IBR. Breast-Q, Body Esteem Scale for Adults and Adolescents (BESAA) and Hospital Anxiety and Depression Scale (HADS) were sent to women who had experienced implant loss during the last 10 years. Women of a similar age who were reconstructed, without complications, during the same period were controls. The results suggest that there might be a more permanent negative effect on satisfaction and QoL following implant loss. The proportion of possible cases of depression was higher among patients who had experienced implant loss. The findings could indicate that in patients with an elevated risk for implant loss, the possible benefits with IBR should be carefully balanced against the effects of implant loss.

有几个优点被建议立即乳房重建(IBR);然而,很少有高质量的科学证据证实这些优势。与延迟乳房重建(DBR)相比,IBR的缺点包括并发症的风险增加,如植入物丢失(患病率为5-10%对1%)。对于女性如何经历种植体丢失以及它如何影响患者的长期满意度和生活质量(QoL)知之甚少。我们研究的主要目的是比较IBR术后种植体丢失的女性患者的满意度和生活质量,以及成功的IBR患者的满意度和生活质量。研究人员将Breast-Q、成人和青少年身体自尊量表(BESAA)和医院焦虑和抑郁量表(HADS)发给在过去10年内经历过植入物丢失的妇女。对照组是年龄相仿的女性,在同一时期进行了重建,没有并发症。结果表明,种植体丢失可能会对满意度和生活质量产生更持久的负面影响。在经历过种植体丢失的患者中,可能出现抑郁症的比例更高。研究结果表明,对于种植体丢失风险较高的患者,应仔细权衡IBR可能带来的益处与种植体丢失的影响。
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引用次数: 0
Breast augmentation under local anesthesia with intercostal blocks and light sedation. 肋间阻滞和轻度镇静局部麻醉下隆胸。
IF 1.2 4区 医学 Q3 ORTHOPEDICS Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2022.2069789
Martine Ditlev, Erik Loentoft, Lisbet R Hölmich

Introduction: This study of breast augmentations performed under local anesthesia with intercostal blocks and light sedation describes the outcomes and evaluates benefits and complications.

Method: From December 2005 until August 2019, 335 women consecutively underwent bilateral breast augmentation procedures. The anesthetic protocol consisted of an initial intravenous bolus of 1 mg midazolam and 0.25 mg alfentanil preoperatively. In 2017, this was changed to 2-4 mg midazolam intramuscularly, 1 mg midazolam intravenously, and 2.5 µg sufentanil intravenously. Intercostal blocks were injected at the midaxillary line into the intercostal spaces two to seven. The operating field was infiltrated with tumescent local anesthesia. Retrospective data extraction from patients' medical charts was done, registering demographics, dosage of anesthesia, surgical characteristics, complications, and reoperation rates.

Results: Two hundred and eighty-one women underwent primary augmentation and 54 had implant replacement. The most common complications included suboptimal cosmetic results, asymmetry, and healing-related problems. The overall rate of reoperation was 16.1% within an average follow-up period of 2 years, ranging from 0 to 12.5 years. The majority of the reoperations were due to cosmetic reasons. The change in anesthetic regime was associated with a significantly (p < 0.0001) decreased need for supplementary medication with no increased risk of complications.

Conclusion: Breast augmentations in local anesthesia with intercostal blocks and light sedation can be performed safely and can serve as an alternative to procedures in general anesthesia.

简介:本研究在肋间阻滞和轻度镇静的局部麻醉下进行隆胸,描述了结果并评估了获益和并发症。方法:从2005年12月至2019年8月,335名女性连续接受了双侧隆胸手术。麻醉方案包括术前静脉滴注咪达唑仑1mg和阿芬太尼0.25 mg。2017年,这改为肌肉注射2-4毫克咪达唑仑,静脉注射1毫克咪达唑仑,静脉注射2.5微克舒芬太尼。肋间阻滞从腋中线注射到肋间间隙2至7处。局部麻醉肿胀性浸润手术野。从患者病历中提取回顾性数据,记录人口统计学、麻醉剂量、手术特点、并发症和再手术率。结果:261名妇女接受了首次隆胸,54名妇女接受了假体置换。最常见的并发症包括不理想的美容效果、不对称和与愈合有关的问题。平均随访2年(0 ~ 12.5年),总再手术率为16.1%。大多数的再手术是由于美观的原因。结论:在肋间阻滞和轻度镇静的局部麻醉下隆胸可以安全进行,并且可以作为全麻手术的替代方案。
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引用次数: 0
Evaluation of an assessment scale for aesthetic outcome in breast reconstructions based on digital photos in both 2D and 3D format. 基于2D和3D格式数码照片的乳房重建美学效果评估量表的评价。
IF 1.2 4区 医学 Q3 ORTHOPEDICS Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2022.2152820
Linda Tallroth, Nathalie Mobargha, Patrik Velander, Stina Klasson, Magnus Becker

The aesthetic outcome is crucial in a breast reconstruction. Our aim was to evaluate the intra- and interrater reliability of an aesthetic outcome assessment scale with digital photos of breast reconstructions in two-dimensional (2D) and three-dimensional (3D) format. Thirty-three women with delayed breast reconstructions, consecutively participating in a five-year follow-up between November 2019 and June 2021, were included in the study. Of these, 14 were reconstructed with an expander prosthesis (EP) and 19 with a deep inferior epigastric perforator (DIEP) flap. Photos of the breasts were assessed in 2D and 3D format by expert, layman and patient panels. Data were analysed with the weighted kappa (wk) statistics. The intrarater agreements were moderate to substantial, with wk between 0.66 and 0.73 for the panels. Within the panels, the interrater agreements were 0.46-0.62. Moderate agreements were found between the matched 2D and 3D format photos (wk 0.62-0.66). The patient panel graded scar appearance worse in 3D compared with 2D format. In all panels, there was a tendency towards DIEP flap reconstructions receiving higher aesthetic outcome grades compared with EP. Thus, the aesthetic outcome assessment scale demonstrated acceptable agreements between the individual panellists and within the panels. Scars captured in 3D format may provide a greater resemblance to the reality compared with 2D. Implications for clinics remain to be further studied.

在乳房重建中,美学效果是至关重要的。我们的目的是用二维(2D)和三维(3D)格式的乳房重建数码照片来评估美学结果评估量表的内部和内部可靠性。该研究包括33名延迟乳房重建的女性,她们在2019年11月至2021年6月期间连续参加了为期五年的随访。其中,14例用扩张假体(EP)重建,19例用深下腹壁穿支(DIEP)皮瓣重建。乳房的照片由专家、外行人和患者小组以2D和3D格式进行评估。采用加权kappa (wk)统计方法对数据进行分析。内部协议从中等到大量不等,专家组的周长在0.66至0.73之间。在小组内,报价者间的协定为0.46-0.62。匹配的2D和3D格式照片之间存在中等程度的一致性(周数0.62-0.66)。与2D格式相比,3D格式的患者评分瘢痕外观更差。在所有面板中,与EP相比,DIEP皮瓣重建倾向于获得更高的美学结果等级。因此,美学结果评估量表显示了个别小组成员之间和小组内部可接受的协议。与2D相比,3D格式的疤痕可能更接近现实。对临床的影响仍有待进一步研究。
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引用次数: 0
Single versus dual venous anastomosis in radial forearm free flaps in head and neck reconstruction. 前臂桡骨游离皮瓣在头颈部重建中的单静脉与双静脉吻合。
IF 1.2 4区 医学 Q3 ORTHOPEDICS Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2022.2152821
Hanjin Ruan, Zhengxue Han

A retrospective cohort study of 253 radial forearm free flap (RFFF) procedures in head and neck reconstruction performed in our department between 2005 and 2018 was reviewed. In order to explore the effects between single and dual anastomoses, we applied Fisher's exact test for statistical analysis. Although no flap failure was identified, more venous compromises were observed in single anastomosis group (5/80 vs. 1/173). We conclude that dual venous anastomoses can reduce venous compromise resulted from unexpected causes in RFFF transfer. Therefore, we especially recommend dual venous anastomoses for those who cannot withstand a second surgery.

回顾了2005年至2018年我科253例桡骨前臂游离皮瓣(RFFF)头颈部重建的回顾性队列研究。为了探讨单吻合术和双吻合术之间的影响,我们采用Fisher精确检验进行统计分析。虽然没有发现皮瓣衰竭,但单一吻合组观察到更多的静脉损伤(5/80 vs 1/173)。我们的结论是,双静脉吻合术可以减少RFFF转移中因意外原因引起的静脉损伤。因此,我们特别推荐双静脉吻合术对那些不能承受第二次手术。
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引用次数: 0
Pain, hand function, activity performance and apprehensiveness, in patients with surgically treated distal radius fractures. 手术治疗桡骨远端骨折患者的疼痛、手功能、活动表现和忧虑。
IF 1.2 4区 医学 Q3 ORTHOPEDICS Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2022.2060992
J Blomstrand, G Kjellby Wendt, J Karlsson, J Wangdell, M Fagevik Olsén

Distal radius fracture (DRF) is a common injury, affecting both function and activity performance. Postoperative rehabilitation is an essential part of the treatment of a surgically treated DRF. The study aims were to assess pain, hand function, activity performance and apprehensiveness and their association, during the first three months after a surgically treated DRF. Eighty-eight patients with a DRF were assessed for pain, hand function, activity performance and apprehensiveness three days and two, six and 12 weeks after surgery. The results indicated that pain, range of motion (ROM), grip strength, apprehensiveness, and activity performance (PRWE) improved significantly between follow-ups (p < .001-.01). Apprehensiveness correlated moderately with activity performance on all visits (0.40-0.47, p < .01), which implies a correlation between the variables, but the regression model showed that the differences in the PRWE at twelve weeks cannot be explained by the differences in apprehensiveness or range of motion at cast removal. At 12 weeks, the study participants had regained almost 70% of their grip strength and 74-96% of the ROM of the uninjured hand.The study shows that, during the study period, the participants improved in both pain, hand function and activity performance, and indicates that a simple question on apprehensiveness in terms of using the injured hand in daily life could be an important factor in distal radius fracture rehabilitation.

桡骨远端骨折(DRF)是一种常见的损伤,影响功能和活动能力。术后康复是手术治疗DRF的重要组成部分。该研究的目的是评估手术治疗DRF后头三个月的疼痛、手功能、活动表现和忧虑性及其相关性。88例DRF患者在手术后3天、2周、6周和12周对疼痛、手功能、活动表现和忧虑性进行评估。结果表明,在随访期间,疼痛、活动范围(ROM)、握力、忧虑性和活动表现(PRWE)均有显著改善(p < 0.05)
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引用次数: 0
Corset trunkoplasty is able to preserve postoperative abdominal skin sensation in massive weight loss patients. 胸衣躯干成形术能够保留大量减肥患者术后腹部皮肤感觉。
IF 1.2 4区 医学 Q3 ORTHOPEDICS Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2022.2152822
Kathrin Bachleitner, Maximilian Mahrhofer, Friedrich Knam, Thomas Schoeller, Laurenz Weitgasser

Conventional abdominoplasty techniques commonly cause postoperative peri- and infraumbilical skin hypesthesia due to abdominal skin flap undermining. The aim of this study was to evaluate abdominal skin sensation after corset trunkoplasty in massive weight loss patients. Forty-nine massive weight loss patients suffering from excess skin underwent corset trunkoplasty between April 2017 and July 2021. Patient demographics and perioperative complications were recorded. Sensibility of the abdominal skin was measured in three qualities postoperatively using a Semmes-Weinstein monofilament, Tip-Therm® device for thermal sensation and a cotton wooden stick for sharp/blunt discrimination. Results were compared with a control group of healthy individuals to create a baseline. Revision surgery for major complications was necessary in five cases (10%) including hematoma and major wound healing disturbances. Minor complications that did not require surgical intervention were observed in eight cases (16%). Postoperative abdominal sensibility did not show any significant difference between the patient and the control group in all 16 measured areas. Sharp/blunt and thermal discrimination was positive in all patients for the whole abdominal surface area. The corset trunkoplasty technique is able to address both horizontal and vertical soft tissue excess in massive weight loss patients and at the same time limits loss of sensibility of the abdominal skin. Compared to conventional abdominoplasty techniques the abdominal sensation can mainly be preserved due to absence of undermining abdominal skin flaps.

由于腹部皮瓣破坏,传统的腹部成形术通常会导致术后脐周和脐下皮肤感觉减退。本研究的目的是评估大量减肥患者在胸衣躯干成形术后腹部皮肤感觉。2017年4月至2021年7月期间,49名因皮肤过多而大幅减肥的患者接受了胸衣躯干成形术。记录患者人口统计资料及围手术期并发症。术后使用Semmes-Weinstein单丝、Tip-Therm®热感觉装置和棉木棍对腹部皮肤的三个质量进行敏感性测量。结果与对照组的健康个体进行比较,以创建基线。5例(10%)的主要并发症需要翻修手术,包括血肿和主要伤口愈合障碍。有8例(16%)出现不需要手术干预的轻微并发症。术后患者与对照组在所有16个测量区域的腹部敏感性均无显著差异。所有患者的整个腹部面积的锐/钝和热辨别均为阳性。胸衣躯干成形术能够解决大量减肥患者的水平和垂直软组织过剩问题,同时限制腹部皮肤敏感性的丧失。与传统的腹部成形术相比,腹部感觉主要是由于没有破坏腹部皮瓣而得以保留。
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引用次数: 0
The association between trauma and paediatric trigger thumb deformity; experience from a single tertiary referral hospital. 创伤与儿童触发拇指畸形之间的关系来自单一三级转诊医院的经验。
IF 1.2 4区 医学 Q3 ORTHOPEDICS Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2022.2032104
Nadia L Salloum, Pauline McGee, Wee L Lam

Whilst the natural history and management of trigger thumb have been thoroughly investigated, the aetiology of the condition remains poorly understood. There are suggestions that this could be a congenital or acquired condition, but evidence remains limited. A history of trauma has repeatedly been noted in a proportion of patients presenting with trigger thumb. This retrospective study reviewed the presentations of 75 cases of trigger thumb in 65 consecutive children who underwent surgery for trigger thumb. We found that 28% of affected digits presented with a traumatic history to the thumb, of those 90% presented immediately post-injury with a flexion deformity. Those who presented with a traumatic history were typically younger at presentation (median age 27.0 months compared to 37.5 months for traumatic and atraumatic presentations respectively) but also tended to present earlier than the atraumatic group (one day compared to 12.17 months respectively). We conclude that a single traumatic event is unlikely to be the causative factor in the development of trigger thumb in children but it may expediate the development of individuals who are predisposed.

虽然扳机拇指的自然历史和管理已被彻底调查,但该病的病因学仍然知之甚少。有迹象表明,这可能是先天性或后天的条件,但证据仍然有限。有创伤史的患者中有一定比例的患者表现为触发拇指。本回顾性研究回顾了65例连续接受手术治疗的儿童中75例触发拇指的表现。我们发现28%的受影响的手指表现为拇指的创伤史,其中90%的人在受伤后立即表现为屈曲畸形。那些有创伤史的患者通常在发病时更年轻(中位年龄为27.0个月,创伤和非创伤分别为37.5个月),但也倾向于比非创伤组更早发病(一天,分别为12.17个月)。我们的结论是,单一的创伤事件不太可能是儿童扳机拇指发展的致病因素,但它可能会加速易感个体的发展。
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引用次数: 1
An external validation of a novel predictive algorithm for male nipple areolar positioning: an improvement to current practice through a multicenter endeavor. 一种新的男性乳头乳晕定位预测算法的外部验证:通过多中心努力对当前实践的改进。
IF 1.2 4区 医学 Q3 ORTHOPEDICS Pub Date : 2023-02-01 DOI: 10.1080/2000656X.2021.1994982
Floyd W Timmermans, Laure Ruyssinck, Sterre E Mokken, Marlon Buncamper, Kevin M Veen, Margriet G Mullender, Karel E Y Claes, Mark-Bram Bouman, Stanislas Monstrey, Timotheus C van de Grift

The correct positioning of nipple-areolar complexes (NAC) during gender-affirming mastectomies remains a particular challenge. Recently, a Dutch two-step algorithm was proposed predicting the most ideal NAC-position derived from a large cisgender male cohort. We aimed to externally validate this algorithm in a Belgian cohort. The Belgian validation cohort consisted of cisgender men. Based on patient-specific anthropometry, the algorithm predicts nipple-nipple distance (NN) and sternal-notch-to-nipple distance (SNN). Predictions were externally validated using the performance measures: R2-value, means squared error (MSE) and mean absolute percentage error (MAPE). Additionally, data were collected from a Belgian and Dutch cohort of transgender men having undergone mastectomy with free nipple grafts. The observed and predicted NN and SNN were compared and the inter-center variability was assessed. A total of 51 Belgian cisgender and 25 transgender men were included, as well as 150 Dutch cisgender and 96 transgender men. Respectively, the performance measures (R2-value, MSE and MAPE) for NN were 0.315, 2.35 (95%CI:0-6.9), 4.9% (95%CI:3.8-6.1) and 0.423, 1.51 (95%CI:0-4.02), 4.73%(95%CI:3.7-5.7) for SNN. When applying the algorithm to both transgender cohorts, the predicted SNN was larger in both Dutch (17.1measured(±1.7) vs. 18.7predicted(±1.4), p= <0.001) and Belgian (16.2measured(±1.8) vs. 18.4predicted(±1.5), p= <0.001) cohorts, whereas NN was too long in the Belgian (22.0measured(±2.6) vs. 21.2predicted(±1.6), p = 0.025) and too short in the Dutch cohort (19.8measured(±1.8) vs. 20.7predicted(±1.9), p = 0.001). Both models performed well in external validation. This indicates that this two-step algorithm provides a reproducible and accurate clinical tool in determining the most ideal patient-tailored NAC-position in transgender men seeking gender-affirming chest surgery.

在性别确认乳房切除术中,乳头-乳晕复合物(NAC)的正确定位仍然是一个特别的挑战。最近,荷兰人提出了一种两步算法,从一个大型顺性别男性队列中预测最理想的nac位置。我们的目标是在比利时队列中外部验证该算法。比利时验证队列由顺性别男性组成。基于患者特异性人体测量,该算法预测乳头-乳头距离(NN)和胸骨-缺口-乳头距离(SNN)。预测使用性能指标进行外部验证:r2值、均方误差(MSE)和平均绝对百分比误差(MAPE)。此外,我们还收集了来自比利时和荷兰的一组变性男性的数据,这些男性接受了乳房切除术和游离乳头移植。比较了观测和预测的NN和SNN,并评估了中心间变异性。调查对象包括51名比利时顺性男性和25名跨性别男性,以及150名荷兰顺性男性和96名跨性别男性。神经网络的性能指标(r2值,MSE和MAPE)分别为0.315,2.35 (95%CI:0-6.9), 4.9% (95%CI:3.8-6.1), SNN的性能指标为0.423,1.51 (95%CI:0-4.02), 4.73%(95%CI:3.7-5.7)。当将该算法应用于两个跨性别队列时,荷兰人的预测SNN都较大(17.1实测(±1.7)vs. 18.7预测(±1.4),p=实测(±1.8)vs. 18.4预测(±1.5),p=实测(±2.6)vs. 21.2预测(±1.6),p= 0.025),荷兰人的预测SNN过短(19.8实测(±1.8)vs. 20.7预测(±1.9),p= 0.001)。两种模型在外部验证中均表现良好。这表明,该两步算法为寻求性别确认胸部手术的跨性别男性确定最理想的患者定制nac位置提供了一种可重复且准确的临床工具。
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引用次数: 1
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Journal of Plastic Surgery and Hand Surgery
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