Pub Date : 1900-01-01DOI: 10.5114/AMSCD.2021.105392
Onur Ag, Yusuf Bozcan, M. Dinçer
Introduction: Volvulus is defined as an acute bowel dilatation, which must be treated after the diagnosis in a short time, which otherwise can cause necrosis and perforation of the bowel. Chronic constipation and neurological diseases are the most common causes in some countries. In this study, patients with sigmoid volvulus who were treated and followed up were ex-amined, the association of it with neurological diseases was investigated, and the demographic characteristics of the patients, treatment approaches, and results were presented. Material and methods: Patients who underwent colonic volvulus with dementia between January 2010 and August 2020 were retrospectively re-viewed. The demographic characteristics and histopathological diagnosis of the patients were recorded. Differences in treatment modalities and results of patients with volvulus were statistically analyzed. Results: Seventy-eight patients who had sigmoid volvulus and dementia were included the study. The median age was 82.0 years and males repre-sented 71.8% of the patients. All the patients had abdominal pain, while the other common symptoms were vomiting, abdominal distension and constipation. The complication rate was statistically significantly higher in surgical treatment than endoscopic procedures and spontaneously detorsioned ( p = 0.011). The median length of stay was statistically significantly different in the surgery group, endoscopic procedure group and spontaneously detorsioned group ( p < 0.001). Conclusions: The prevalence of volvulus is high in individuals with neurological disease. Successful results were obtained with non-surgical follow-up after endoscopic detorsion in the selected patient group in the results of this study, and mortality and morbidity were at lower rates than surgery.
{"title":"Impact of watch and wait procedure after endoscopic detorsion for sigmoid volvulus in high risk dementia patients","authors":"Onur Ag, Yusuf Bozcan, M. Dinçer","doi":"10.5114/AMSCD.2021.105392","DOIUrl":"https://doi.org/10.5114/AMSCD.2021.105392","url":null,"abstract":"Introduction: Volvulus is defined as an acute bowel dilatation, which must be treated after the diagnosis in a short time, which otherwise can cause necrosis and perforation of the bowel. Chronic constipation and neurological diseases are the most common causes in some countries. In this study, patients with sigmoid volvulus who were treated and followed up were ex-amined, the association of it with neurological diseases was investigated, and the demographic characteristics of the patients, treatment approaches, and results were presented. Material and methods: Patients who underwent colonic volvulus with dementia between January 2010 and August 2020 were retrospectively re-viewed. The demographic characteristics and histopathological diagnosis of the patients were recorded. Differences in treatment modalities and results of patients with volvulus were statistically analyzed. Results: Seventy-eight patients who had sigmoid volvulus and dementia were included the study. The median age was 82.0 years and males repre-sented 71.8% of the patients. All the patients had abdominal pain, while the other common symptoms were vomiting, abdominal distension and constipation. The complication rate was statistically significantly higher in surgical treatment than endoscopic procedures and spontaneously detorsioned ( p = 0.011). The median length of stay was statistically significantly different in the surgery group, endoscopic procedure group and spontaneously detorsioned group ( p < 0.001). Conclusions: The prevalence of volvulus is high in individuals with neurological disease. Successful results were obtained with non-surgical follow-up after endoscopic detorsion in the selected patient group in the results of this study, and mortality and morbidity were at lower rates than surgery.","PeriodicalId":169652,"journal":{"name":"Archives of Medical Science - Civilization Diseases","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127108483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5114/amscd.2020.95224
Jayakumar Sreenivasan, M. Khan, Qiyu Wang, S. Ranka, T. Akhtar, Jishanth Mattumpuram, R. Agrawal, M. Zhuo, W. Aronow, Neha Yadav
Introduction: The association between serum albumin level and the risk of contrast-induced acute kidney injury (CI-AKI) after coronary angiography has not been well established. Material and methods: A retrospective chart review was performed for all patients who underwent coronary angiography with or without percutaneous coronary intervention (PCI) at a tertiary care medical center over a peri-od of 5 years. CI-AKI was defined as an absolute increase in creatinine of 0.3 mg/dl from baseline within 48 h of contrast exposure. Mean pre-procedural albumin level was compared between patients who developed CI-AKI and those who did not. The optimal cut-off point was obtained from the receiver operating characteristic (ROC) curve and univariate multiple logistic regression analysis was used to assess the associated risk of CI-AKI. Results: Among 1319 patients (females = 32.3%, mean age: 58.2 ± 13.6 years) included in the study, 201 (15.2%) developed CI-AKI. Baseline serum albumin (3.5 vs. 3.8 gm/dl, p < 0.001) was significantly lower in patients who developed CI-AKI. ROC curve analysis revealed an optimal cutoff value for serum albumin of 3.85 gm/dl to predict CI-AKI with 67.2% sensitivity and 52.2% specificity (area under the curve (AUC) = 0.62, p < 0.001). Serum albumin < 3.85 gm/dl is significantly associated with higher risk of developing CI-AKI (adjusted odds ratio (AOR) = 1.5, 95% CI: 1.1–2.1, p = 0.02). Conclusions: Serum albumin < 3.85 gm/dl is an independent predictor of CI-AKI in patients undergoing coronary angiography.
简介:血清白蛋白水平与冠状动脉造影后造影剂诱导的急性肾损伤(CI-AKI)风险之间的关系尚未得到很好的证实。材料和方法:对所有在三级医疗中心接受冠状动脉造影(有或没有经皮冠状动脉介入治疗(PCI))的患者进行回顾性图表回顾，时间跨度为5年。CI-AKI被定义为在造影剂暴露48小时内肌酐比基线绝对增加0.3 mg/dl。比较发生CI-AKI患者和未发生CI-AKI患者的平均术前白蛋白水平。从受试者工作特征(ROC)曲线中获得最佳截断点，采用单因素多元logistic回归分析评估CI-AKI相关风险。结果:纳入研究的1319例患者(女性= 32.3%，平均年龄:58.2±13.6岁)中，201例(15.2%)发生CI-AKI。CI-AKI患者的基线血清白蛋白(3.5 vs 3.8 gm/dl, p < 0.001)显著降低。ROC曲线分析显示，血清白蛋白3.85 gm/dl预测CI-AKI的最佳临界值为67.2%的敏感性和52.2%的特异性(曲线下面积(AUC) = 0.62, p < 0.001)。血清白蛋白< 3.85 gm/dl与发生CI- aki的高风险显著相关(校正优势比(AOR) = 1.5, 95% CI: 1.1-2.1, p = 0.02)。结论:血清白蛋白< 3.85 gm/dl是冠状动脉造影患者CI-AKI的独立预测因子。
{"title":"Serum albumin level as a predictor of contrast-induced acute kidney injury following coronary angiography","authors":"Jayakumar Sreenivasan, M. Khan, Qiyu Wang, S. Ranka, T. Akhtar, Jishanth Mattumpuram, R. Agrawal, M. Zhuo, W. Aronow, Neha Yadav","doi":"10.5114/amscd.2020.95224","DOIUrl":"https://doi.org/10.5114/amscd.2020.95224","url":null,"abstract":"Introduction: The association between serum albumin level and the risk of contrast-induced acute kidney injury (CI-AKI) after coronary angiography has not been well established. Material and methods: A retrospective chart review was performed for all patients who underwent coronary angiography with or without percutaneous coronary intervention (PCI) at a tertiary care medical center over a peri-od of 5 years. CI-AKI was defined as an absolute increase in creatinine of 0.3 mg/dl from baseline within 48 h of contrast exposure. Mean pre-procedural albumin level was compared between patients who developed CI-AKI and those who did not. The optimal cut-off point was obtained from the receiver operating characteristic (ROC) curve and univariate multiple logistic regression analysis was used to assess the associated risk of CI-AKI. Results: Among 1319 patients (females = 32.3%, mean age: 58.2 ± 13.6 years) included in the study, 201 (15.2%) developed CI-AKI. Baseline serum albumin (3.5 vs. 3.8 gm/dl, p < 0.001) was significantly lower in patients who developed CI-AKI. ROC curve analysis revealed an optimal cutoff value for serum albumin of 3.85 gm/dl to predict CI-AKI with 67.2% sensitivity and 52.2% specificity (area under the curve (AUC) = 0.62, p < 0.001). Serum albumin < 3.85 gm/dl is significantly associated with higher risk of developing CI-AKI (adjusted odds ratio (AOR) = 1.5, 95% CI: 1.1–2.1, p = 0.02). Conclusions: Serum albumin < 3.85 gm/dl is an independent predictor of CI-AKI in patients undergoing coronary angiography.","PeriodicalId":169652,"journal":{"name":"Archives of Medical Science - Civilization Diseases","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134524013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5114/amscd.2022.119966
S. Nykytyuk, S. Marchyshyn, S. Klymnyuk, M. Shkilna, S. Levenets
{"title":"Borelis Pro phytomedicine for the complex treatment of Lyme borreliosis in children","authors":"S. Nykytyuk, S. Marchyshyn, S. Klymnyuk, M. Shkilna, S. Levenets","doi":"10.5114/amscd.2022.119966","DOIUrl":"https://doi.org/10.5114/amscd.2022.119966","url":null,"abstract":"","PeriodicalId":169652,"journal":{"name":"Archives of Medical Science - Civilization Diseases","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131631402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5114/AMSCD.2021.107844
L. Spahiu, Egzona Berisha, R. Hadziselimovic, H. Nefic, G. Temaj
of the age group of 6–12 years, and 10 patients of the age group of 12–18 years. Conclusions: Data suggest that pediatric cases of COVID-19 in adolescents have more severe symptoms than in the other age groups; however, in general children tend to cope much more easily with the virus than adults.
{"title":"COVID-19 implications at the Clinical University Center in Kosovo – Department of Pediatrics","authors":"L. Spahiu, Egzona Berisha, R. Hadziselimovic, H. Nefic, G. Temaj","doi":"10.5114/AMSCD.2021.107844","DOIUrl":"https://doi.org/10.5114/AMSCD.2021.107844","url":null,"abstract":"of the age group of 6–12 years, and 10 patients of the age group of 12–18 years. Conclusions: Data suggest that pediatric cases of COVID-19 in adolescents have more severe symptoms than in the other age groups; however, in general children tend to cope much more easily with the virus than adults.","PeriodicalId":169652,"journal":{"name":"Archives of Medical Science - Civilization Diseases","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130596653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5114/amscd.2022.119600
P. Natarajan, V. Rekha, Anita Murali, Bhuminathan Swamikannu
{"title":"Newer congeners of doxycycline – do they hold promise for periodontal therapy?","authors":"P. Natarajan, V. Rekha, Anita Murali, Bhuminathan Swamikannu","doi":"10.5114/amscd.2022.119600","DOIUrl":"https://doi.org/10.5114/amscd.2022.119600","url":null,"abstract":"","PeriodicalId":169652,"journal":{"name":"Archives of Medical Science - Civilization Diseases","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123865901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5114/amscd.2019.84522
M. Dinçer, E. Aygen
Introduction: Incisional hernia continues to be one of the major problems of surgery due to its high incidence rate and high morbidity. The aims of this study are to compare different repair techniques with primary repair techniques for the risk of incisional hernia. Material and methods: High-risk patients who had a midline incision of the abdomen were included in this study. Patients were divided into four groups. Each group contained 20 patients. Patients of group 1 were operated on using primary repair. In group 2 Cardiff repair technique was used. The patients in group 3 were repaired with Keel technique. The patients of group 4 were repaired with onlay technique. Patients were followed up with physical examination at 3-month periods in the first year after surgery and 6-month periods in the following two years. Incisional hernia, occurrence time and other complications were noted. Results: Eighty patients who had high risk of incisional hernia were included in this study. 47.5% of them were female and 52.5% of them were male. The average age of patients was 59.2 ±12.95. Average hospitalization time was 8.5 days (4–28 days). Average follow-up was 18 months (6–34 months). In total 4 (5%) patients had recurrence. Fifteen percent of patients in group 1 had recurrence and 5% of patients in group 2 had recurrence. There was no recurrence in other groups. There was no significant difference for incisional hernia and the other complications between groups (p = 0.368). Conclusions: There was no significant difference between the techniques in terms of the development of incisional hernias or complications.
{"title":"Is there any superiority of the different abdominal closure techniques for primary closure in high-risk patients?","authors":"M. Dinçer, E. Aygen","doi":"10.5114/amscd.2019.84522","DOIUrl":"https://doi.org/10.5114/amscd.2019.84522","url":null,"abstract":"Introduction: Incisional hernia continues to be one of the major problems of surgery due to its high incidence rate and high morbidity. The aims of this study are to compare different repair techniques with primary repair techniques for the risk of incisional hernia. Material and methods: High-risk patients who had a midline incision of the abdomen were included in this study. Patients were divided into four groups. Each group contained 20 patients. Patients of group 1 were operated on using primary repair. In group 2 Cardiff repair technique was used. The patients in group 3 were repaired with Keel technique. The patients of group 4 were repaired with onlay technique. Patients were followed up with physical examination at 3-month periods in the first year after surgery and 6-month periods in the following two years. Incisional hernia, occurrence time and other complications were noted. Results: Eighty patients who had high risk of incisional hernia were included in this study. 47.5% of them were female and 52.5% of them were male. The average age of patients was 59.2 ±12.95. Average hospitalization time was 8.5 days (4–28 days). Average follow-up was 18 months (6–34 months). In total 4 (5%) patients had recurrence. Fifteen percent of patients in group 1 had recurrence and 5% of patients in group 2 had recurrence. There was no recurrence in other groups. There was no significant difference for incisional hernia and the other complications between groups (p = 0.368). Conclusions: There was no significant difference between the techniques in terms of the development of incisional hernias or complications.","PeriodicalId":169652,"journal":{"name":"Archives of Medical Science - Civilization Diseases","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127382910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5114/amscd.2023.125845
A. Gulcu, R. Dinçer
Introduction: Massive rotator cuff tears (MRCTs) remain a controversial problem for clinicians. There are several recommendations in the literature, from various surgical techniques to the effectiveness of conservative treat-ment. In this study, we aimed to compare clinical outcomes and functional results of open superior capsular reconstruction for massive rotator cuff tear and arthroscopic partial rotator cuff repair with margin convergence. Material and methods: This study included 40 patients with massive rotator cuff tears that could not be treated with arthroscopic partial repair with margin convergence or open superior capsular reconstruction. The patients were divided into 2 groups according to the treatment method. Patient assignments for each group were not randomized. Group 1 consisted of 20 patients who underwent open superior capsular reconstruction
{"title":"A comparison of partial repair with arthroscopic margin convergence suture and open superior capsular reconstruction in patients with massive rotator cuff tear","authors":"A. Gulcu, R. Dinçer","doi":"10.5114/amscd.2023.125845","DOIUrl":"https://doi.org/10.5114/amscd.2023.125845","url":null,"abstract":"Introduction: Massive rotator cuff tears (MRCTs) remain a controversial problem for clinicians. There are several recommendations in the literature, from various surgical techniques to the effectiveness of conservative treat-ment. In this study, we aimed to compare clinical outcomes and functional results of open superior capsular reconstruction for massive rotator cuff tear and arthroscopic partial rotator cuff repair with margin convergence. Material and methods: This study included 40 patients with massive rotator cuff tears that could not be treated with arthroscopic partial repair with margin convergence or open superior capsular reconstruction. The patients were divided into 2 groups according to the treatment method. Patient assignments for each group were not randomized. Group 1 consisted of 20 patients who underwent open superior capsular reconstruction","PeriodicalId":169652,"journal":{"name":"Archives of Medical Science - Civilization Diseases","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114892340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5114/AMSCD.2020.100838
L. Sułkowski, C. Osuch, Maciej Matyja, A. Matyja
The autogenous arteriovenous fistula (AVF) is an access of choice for chronically hemodialyzed patients [1–4], preferred over central venous catheter placement [5]. The AVF’s access vein on the upper extremity can be either the cephalic or basilic vein (BV). The forearm AVF is the first choice. In the case of inadequate, narrow or thrombosed forearm veins, the arm veins can be used to create an AVF. When the favorably located cephalic vein is narrow or thrombosed, the BV remains an alternative [6]. The deep location of BV in the arm makes this vein unsuitable for puncture without superficialization [1, 2, 7]. There are several techniques enabling the use of the deeply located BV, including lipectomy, BV elevation and BV tunnel transposition (BVTT) [1, 2, 7, 8]. Therefore, BV AVF remains an access option for difficult cases, along with central venous catheter placement or prosthetic graft AVF [2]. BVTT is technically more complex than catheter placement or prosthetic graft AVF [5, 9], but has all the advantages of autogenous AVF and forms a long and superficial vein segment suitable for cannulation [7].
{"title":"One-stage basilic vein tunneled transposition for hemodialysis access","authors":"L. Sułkowski, C. Osuch, Maciej Matyja, A. Matyja","doi":"10.5114/AMSCD.2020.100838","DOIUrl":"https://doi.org/10.5114/AMSCD.2020.100838","url":null,"abstract":"The autogenous arteriovenous fistula (AVF) is an access of choice for chronically hemodialyzed patients [1–4], preferred over central venous catheter placement [5]. The AVF’s access vein on the upper extremity can be either the cephalic or basilic vein (BV). The forearm AVF is the first choice. In the case of inadequate, narrow or thrombosed forearm veins, the arm veins can be used to create an AVF. When the favorably located cephalic vein is narrow or thrombosed, the BV remains an alternative [6]. The deep location of BV in the arm makes this vein unsuitable for puncture without superficialization [1, 2, 7]. There are several techniques enabling the use of the deeply located BV, including lipectomy, BV elevation and BV tunnel transposition (BVTT) [1, 2, 7, 8]. Therefore, BV AVF remains an access option for difficult cases, along with central venous catheter placement or prosthetic graft AVF [2]. BVTT is technically more complex than catheter placement or prosthetic graft AVF [5, 9], but has all the advantages of autogenous AVF and forms a long and superficial vein segment suitable for cannulation [7].","PeriodicalId":169652,"journal":{"name":"Archives of Medical Science - Civilization Diseases","volume":"22 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131097642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5114/amscd.2020.95227
A. Popow, Anna Wasińska-Krawczyk, B. Interewicz, W. Olszewski, J. Manitius, A. Rydzewska-Rosołowska, A. Rydzewski
Introduction: C-reactive protein (CRP) is an acute phase protein and was shown to be a predictor for all-cause and cardiovascular death in end stage renal disease patients. C-reactive protein is a member of the pentraxin fam-ily and plays a key role in the innate immune response. Several single nucleotide polymorphisms (SNP) associated with plasma CRP levels have been identified. This study aimed to evaluate the frequency of the rs1800947 polymorphism in the human CRP gene in maintenance hemodialysis (HD) patients, and to determine whether it is related to nutritional status. Material and methods: We investigated 99 patients maintained on chronic hemodialysis (HD). 109 apparently healthy volunteers served as a control group. HD subjects were followed for 12 months. Anthropometric measurements were performed, the malnutrition-inflammation scale (MIS) score was determined, and blood samples were obtained within 1 month of enroll-ment and at 3 and 12 months of follow-up. rs1800947 SNP in the CRP gene was genotyped using restriction fragment length polymorphism-polymerase chain reaction. Results: There were no significant differences in the investigated genotype frequencies between HD patients and controls. Moreover, there was no influence of genotype on anthropometric and laboratory indices of nutritional status and MIS score. Conclusions: The results of this study indicate that the rs1800947 single nucleotide polymorphism in the CRP gene does not seem to correlate with nutritional status in hemodialysis patients.
{"title":"CRP single nucleotide polymorphism (rs1800947) and nutritional status in hemodialysis patients","authors":"A. Popow, Anna Wasińska-Krawczyk, B. Interewicz, W. Olszewski, J. Manitius, A. Rydzewska-Rosołowska, A. Rydzewski","doi":"10.5114/amscd.2020.95227","DOIUrl":"https://doi.org/10.5114/amscd.2020.95227","url":null,"abstract":"Introduction: C-reactive protein (CRP) is an acute phase protein and was shown to be a predictor for all-cause and cardiovascular death in end stage renal disease patients. C-reactive protein is a member of the pentraxin fam-ily and plays a key role in the innate immune response. Several single nucleotide polymorphisms (SNP) associated with plasma CRP levels have been identified. This study aimed to evaluate the frequency of the rs1800947 polymorphism in the human CRP gene in maintenance hemodialysis (HD) patients, and to determine whether it is related to nutritional status. Material and methods: We investigated 99 patients maintained on chronic hemodialysis (HD). 109 apparently healthy volunteers served as a control group. HD subjects were followed for 12 months. Anthropometric measurements were performed, the malnutrition-inflammation scale (MIS) score was determined, and blood samples were obtained within 1 month of enroll-ment and at 3 and 12 months of follow-up. rs1800947 SNP in the CRP gene was genotyped using restriction fragment length polymorphism-polymerase chain reaction. Results: There were no significant differences in the investigated genotype frequencies between HD patients and controls. Moreover, there was no influence of genotype on anthropometric and laboratory indices of nutritional status and MIS score. Conclusions: The results of this study indicate that the rs1800947 single nucleotide polymorphism in the CRP gene does not seem to correlate with nutritional status in hemodialysis patients.","PeriodicalId":169652,"journal":{"name":"Archives of Medical Science - Civilization Diseases","volume":"120 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116360901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5114/amscd.2023.124522
K. Saad, A. Elgenidy
{"title":"The believer is not stung from the same place twice: the monkeypox outbreak","authors":"K. Saad, A. Elgenidy","doi":"10.5114/amscd.2023.124522","DOIUrl":"https://doi.org/10.5114/amscd.2023.124522","url":null,"abstract":"","PeriodicalId":169652,"journal":{"name":"Archives of Medical Science - Civilization Diseases","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132758332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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