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Drug-induced atrial fibrillation associated with admission of cardiovascular medications 与心血管药物入院相关的药物性心房颤动
Pub Date : 2020-01-01 DOI: 10.20333/2500136-2020-6-5-13
O. Ostroumova, M. S. Chernyaeva, A. Komarova, S. Gorbatenkova, D. Sychev
Admission of certain medications (drugs) can cause the development of atrial fibrillation (AF) in patients having non-evident cardiovascular disease (CVD). Also, it can accelerate the onset of AF in patients with pre-existing CVD. It is important to realize medications as potential cause of AF, especially in elderly people, since aging is associated with comorbidity and use of many medications simultaneously, that can lead to higher incidence of druginduced AF (DI AF). The article provides literature review on medications used to treat CVD, the admission of which can lead to the development of DI AF. Its onset can be associated with the use of cardiotonic, antiarrhythmic and antianginal medications, calcium channel blockers, diuretics, antiplatelet agents and some others with different evidence levels. The frequency, mechanisms of DI AF development and methods for its correction are described.
在患有非明显心血管疾病(CVD)的患者中,某些药物可导致房颤(AF)的发生。此外,它可以加速已有心血管疾病患者房颤的发作。认识到药物是房颤的潜在原因是很重要的,特别是在老年人中,因为衰老与合并症和同时使用多种药物有关,这可能导致药物性房颤(DI AF)的发生率更高。本文综述了用于治疗CVD的药物可导致DI房颤发生的文献,其发病可能与使用强心剂、抗心律失常和抗心绞痛药物、钙通道阻滞剂、利尿剂、抗血小板药物等相关,证据水平不同。介绍了DI AF发生的频率、机理和校正方法。
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引用次数: 2
Review of the theses topics on specialties 14.01.04 – internal diseases and 14.01.08 – pediatrics considered in 2019 by the dissertation council D 208.037.01 对论文委员会D 208.037.01在2019年审议的专业14.01.04 -内科疾病和14.01.08 -儿科的论文主题进行审查
Pub Date : 2020-01-01 DOI: 10.20333/2500136-2020-5-109-114
S. Shtarik
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引用次数: 0
The use of mass spectrometry in cervical pathology diagnostics (literature review 质谱法在宫颈病理诊断中的应用(文献综述)
Pub Date : 2020-01-01 DOI: 10.20333/2500136-2020-3-30-37
V. Rachkovskaya, A. P. Gorbunov, A. Pashov, L. Volkova
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引用次数: 3
Viability of tuberculosis mycobacterium in autopsy material preserved in formaldehyde solution 甲醛溶液中保存的尸检材料中结核分枝杆菌的生存能力
Pub Date : 2020-01-01 DOI: 10.20333/2500136-2020-1-73-77
A. R. Egorova, T. G. Mihey, A. Kotikov, Krasnoyarsk territorial Tb dispensary
Цель исследования. Оценка сохранения жизнеспособности микобактерий во фрагментах легких, фиксированных в 10 % водном растворе формальдегида. Материал и методы. Фрагменты легких умерших с очагами туберкулеза были фиксированы в 10 % формалине с последующим проведением бактериологического исследования. Результаты. Рост микобактерий был выявлен в двух из 218 фрагментов легких. Один фрагмент легкого имел размеры 1.0х1.0х1.0 см, другой 2.0х2.0х2.0 см. В остальных 216 фрагментах роста микобактерий обнаружено не было. На этом основании был сделан вывод о низком риске заражения врачей-патологоанатомов и лабораторных работников при работе с материалом, взятым от туберкулезных больных и фиксированном в формалине. Заключение. Представленные рекомендации не исключают использование средств персональной защиты во время работы с материалом, забранным от инфицированных туберкулезом. Выживаемость микобактерий в материале, фиксированном в формалине возможна лишь в единичных случаях. Ключевые слова: аутопсийный материал, микобактерии туберкулеза, формалин, риск заражения туберкулезом. Конфликт интересов. Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи. Для цитирования: Егорова АР, Михей ТГ, Котиков АР. Жизнеспособность микобактерий туберкулеза в аутопсийном материале, фиксированном в растворе формальдегида. Сибирское медицинское обозрение. 2020;(1):73-77. DOI: 10.20333/2500136-2020-1-73-77
目的研究。估计霉菌在10%甲醛溶液中存在于肺部碎片中的存活能力。材料和方法。死于肺结核的肺部碎片被检测为10%的甲醛,随后进行了细菌学研究。结果。218个肺碎片中有2个显示了真菌的生长。一个肺碎片大小为1.01.01.0厘米,另一个肺碎片大小为2.0x2.0x2.0厘米。在此基础上,人们得出结论,病理学家和实验室工作人员在处理结核病患者和甲醛中固定的材料时感染的风险较低。囚犯。这些建议并不排除在处理从结核病感染材料中提取的材料时使用个人保护措施。在甲醛中固定的物质中,真菌的生存能力只有在罕见的情况下才能实现。关键字:尸检材料,结核病真菌,甲醛,结核病的风险。利益冲突。提交人声称,本文的出版没有明显和潜在的利益冲突。引用yogorva ar, mihei tg,海豹突击队。结核病真菌在甲醛溶液中发现的尸检材料中具有弹性。西伯利亚医学评论2020;(1): 73 - 77。DOI: 10.20333/2500136 2020 - 1 - 73 - 77
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引用次数: 0
Сlinical case: non-diff erentiated cardiomyopathy (non-compact left ventricular myocardium) in a child Сlinical病例:儿童无鉴别性心肌病(非致密性左心室心肌)
Pub Date : 2020-01-01 DOI: 10.20333/2500136-2020-3-101-105
E. Skudarnov, Y. Lobanov, O. A. Grigorievskaia, L. Bayunova, L. Strozenko, V. Miller, V. Ponomariov
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引用次数: 0
Problems of acetylsalicylic acid resistance in ischemic stroke prevention (literature review) 抗乙酰水杨酸在缺血性脑卒中预防中的问题(文献综述)
Pub Date : 2020-01-01 DOI: 10.20333/2500136-2020-3-47-53
T. E. Everstova, T. Y. Nikolaeva
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引用次数: 1
Determination of the effectiveness of population information influence on distribution of information about coronavirus infection 确定人群信息对冠状病毒感染信息传播影响的有效性
Pub Date : 2020-01-01 DOI: 10.20333/2500136-2020-4-63-70
O. Kutumova, E. P. Pukhova, E. Demko
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引用次数: 0
Comparison of surgical methods for correcting aortic coarctation in new-borns 纠正新生儿主动脉缩窄的手术方法比较
Pub Date : 2020-01-01 DOI: 10.20333/2500136-2020-1-60-65
P. Teplov, A. Titov, A. Miller, Yu.Yu. Spitchak, V. Sakovich
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引用次数: 1
Assessment of socio-economic losses due to mortality from alcohol-related reasons 评估因酗酒导致的死亡所造成的社会经济损失
Pub Date : 2020-01-01 DOI: 10.20333/2500136-2020-1-100-107
B. Budaev, A. Mikheev, I. Tarmaeva, N. I. Khamnaeva, O. G. Bogdanova, T. V. Gololobova, A. Narkevich, K. Vinogradov
Оценка социально-экономических потерь вследствие смертности от алкогольассоциированных причин Б. С. Будаев1, А. С. Михеев2, И. Ю. Тармаева3, Н.И. Хамнаева4, О. Г. Богданова2,4, Т. В. Гололобова5, А. Н. Наркевич6, К. А. Виноградов6 1Министерство здравоохранения Республики Бурятия, Улан-Удэ 670001, Российская Федерация 2Республиканский наркологический диспансер, Улан-Удэ 670033, Российская Федерация 3Иркутский государственный медицинский университет, Иркутск 664003, Российская Федерация 4Восточно-Сибирский государственный университет технологий и управления, Улан-Удэ 670013, Российская Федерация 5Научно-исследовательский институт дезинфектологии, Москва 117246, Российская Федерация 6Красноярский государственный медицинский университет имени профессора В.Ф. Войно-Ясенецкого, Красноярск 660022, Российская Федерация
评估社会经济损失由于大回转алкогольассоциирова原因Будаев1致死率,a.s.Михеев2,i .Тармаева3Н.И.Хамнаева4Богданова2,4 o年,t . w .Гололобова5 anНаркевич6,k . a .Виноградов6卫生1министерств布里亚特共和国乌兰乌德、670001 2республиканск俄罗斯联邦(笑uday 670033乌兰巴托、俄罗斯联邦伊尔库茨克664003 3иркутск国立医科大学,俄罗斯联邦东西伯利亚技术管理大学乌兰乌德670013,俄罗斯消毒学研究所517246,俄罗斯联邦617246,俄罗斯联邦660022
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引用次数: 0
Serum procollagens, structural and functional characteristics of the heart in prediction of cardiac fibrosis after myocardial infarction 血清前胶原、心脏结构和功能特征对心肌梗死后心肌纤维化的预测作用
Pub Date : 2020-01-01 DOI: 10.20333/2500136-2020-6-75-82
A. Osokina, V. Karetnikova, O. Polikutina, A. Ivanova, O. Gruzdeva, Y. Dyleva, A. Kokov, N. Brel, T. Pecherina, O. Barbarash
The aim of the research is to study the dynamics of fibrosing markers of C-terminal procollagen, type I propeptide (PICP) and N-terminal propeptide type III procollagen (PIIINP) in patients with ST-segment elevation myocardial infarction (STEMI); to identify possible correlation between concentration of PICP and PIIINP with the degree of cardiac fibrosis and diastolic dysfunction (DD) in a year after MI. Material and methods. The analyzed sample included STEMI patients with preserved contractility of the left ventricular myocardium (LV). During MI 1-st day the ejection fraction due to Simpson method was ≥50%. On the 1-st and 12-th days of the disease, as well as in a year, the concentration of PICP, PIIINP in venous blood serum was determined in all the studied participants. Standard echocardiographic study was performed with an assessment of LV diastolic function and determination of the following parameters: e’ (septal part displacement), Em (lateral part displacement), and IOLP (indexed left atrium volume). In a year after STEMI, all patients underwent magnetic resonance imaging (MRI) with a contrast agent to determine the severity of fibrotic myocardial damage. Results. PICP concentration significantly decreased by annual stage relative to hospital period (p <0.001). Changes in PIIINP concentration were revealed during the 1s-t and 12-th days (p <0.001), and during the 12-th day and a year (p = 0.002). Both markers showed increased values on the 1-st day of the disease and did not decrease throughout the study. According to MRI results, it turned out that 57% (n = 49) of the observed patients had no signs of cardiac fibrosis (CF) in a year after myocardial infarction, while 10.5% of patients had a lesion ≥ 16% (n = 9). Significant correlations were obtained between CF ≥16% and PIIINP concentration on the 12-th day of MI (r = 0.72, p = 0.041), between CF ≥16% and e’ (cm / s) on the 12-th day (r = -0.66, p = 0.006). Conclusion. One can assume that it is possible to reveal developing CF risk group and, therefore, the development of DD in a year after STEMI determining the concentration of fibrosis markers at hospital stage.
本研究旨在研究st段抬高型心肌梗死(STEMI)患者c端前胶原、I型前肽(PICP)和n端前肽III型前胶原(PIIINP)纤维化标志物的动态变化;确定心肌梗死后一年内PICP和PIIINP浓度与心肌纤维化程度和舒张功能障碍(DD)之间可能存在的相关性。所分析的样本包括左心室心肌(LV)保持收缩力的STEMI患者。心肌梗死第1- 1天,辛普森法射血分数≥50%。在发病第1天、第12天及一年内测定所有研究对象静脉血中PICP、PIIINP的浓度。进行标准超声心动图研究,评估左室舒张功能并确定以下参数:e '(间隔部位移),Em(侧部位移)和IOLP(索引左心房容积)。STEMI术后一年内,所有患者均行磁共振成像(MRI)造影剂检查,以确定纤维化心肌损伤的严重程度。结果。PICP浓度逐年下降,与住院期比较差异有统计学意义(p <0.001)。PIIINP浓度在第1s-t和第12天变化(p <0.001),在第12天和1年内变化(p = 0.002)。这两种标志物在发病第1天均呈上升趋势,在整个研究过程中均未下降。根据核磁共振结果,结果是57% (n = 49)没有观察到患者的心脏纤维化的迹象(CF)在心肌梗死后的一年,而10.5%的患者病变≥16% (n = 9)。取得了显著的相关性之间的CF和PIIINP浓度≥16%的届天MI (r = 0.72, p = 0.041), CF≥16%之间和e (cm / s)届天(r = -0.66, p = 0.006)。结论。我们可以假设,通过确定住院期纤维化标志物的浓度,可以在STEMI后一年内揭示CF的发展风险组,从而揭示DD的发展。
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Journal of Software Maintenance and Evolution: Research and Practice
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