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Severe Complications in Remnant Gastric Cancer: An Epiphenomenon of Tumor Biology and Surgical Complexity? 残胃癌的严重并发症:肿瘤生物学和手术复杂性的附带现象?
IF 1.9 3区 医学 Q3 ONCOLOGY Pub Date : 2025-12-09 DOI: 10.1002/jso.70165
Yong Zhang
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引用次数: 0
Comment on “A SEER-Based Analysis of Survival Predictors in Stage I Colorectal Cancer” “基于seer的I期结直肠癌生存预测因子分析”评论
IF 1.9 3区 医学 Q3 ONCOLOGY Pub Date : 2025-12-07 DOI: 10.1002/jso.70156
Ahmet Necati Sanli, Deniz Esin Tekcan Sanli
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引用次数: 0
Comment on: Predictive Factors for Failed Sentinel Lymph Node Mapping in Endometrial Cancer: A Retrospective Multicenter Study—Missing Data on Indocyanine Green Injection Timing Relative to Adhesiolysis Warrants Retrospective Subgroup Extraction 评论:子宫内膜癌前哨淋巴结定位失败的预测因素:一项回顾性多中心研究-吲哚菁绿注射时间与粘连溶解相关的缺失数据需要回顾性亚组提取。
IF 1.9 3区 医学 Q3 ONCOLOGY Pub Date : 2025-12-07 DOI: 10.1002/jso.70157
Shuang Xiao
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引用次数: 0
Risk Prediction of Postoperative Pancreatic Fistula After Open Pancreatoduodenectomy Using Objective Indicators Obtained From Preoperative Images 利用术前图像客观指标预测胰十二指肠切除术后胰瘘的风险。
IF 1.9 3区 医学 Q3 ONCOLOGY Pub Date : 2025-12-07 DOI: 10.1002/jso.70155
Shota Kuwabara, Yuta Ishizuka, Hiroyasu Tojima, Yuma Aoki, Kazuyuki Yamamoto, Yasuhito Shoji, Akira Fukunaga, Tatsunosuke Ichimura, Hiroto Manase, Satoshi Hirano

Background and Objectives

Postoperative pancreatic fistula (POPF) is a serious complication following Pancreatoduodenectomy (PD). Accurate prediction of clinically relevant POPF (CR-POPF) is essential to reduce morbidity. Identifying objective, easily measurable preoperative risk factors may improve patient outcomes. Therefore, we aimed to identify significant predictive risk factors for CR-POPF.

Methods

We retrospectively analyzed data from 143 patients who underwent PD. Preoperative computed tomography (CT) or magnetic resonance cholangiopancreatography (MRCP) was used to measure the main pancreatic duct (MPD) diameter, the distance from the peritoneum to the anterior surface of the pancreas (PTP), and the abdominal wall thickness (AWT). The PTP/AWT ratio was calculated as a surrogate marker for the visceral-to-subcutaneous fat ratio (V/S ratio). The liver-to-pancreas mean CT attenuation ratio (late/early phase; L/E ratio) was also assessed. Univariate and multivariable analyses were performed to identify risk factors for CR-POPF.

Results

CR-POPF occurred in 33 (23.1%) patients. Multivariable analysis identified V/S ratio ≥ 3.5 (OR: 3.55, p = 0.041), and L/E ratio < 1.2 (OR: 6.07, p = 0.004) as independent risk predictors of CR-POPF.

Conclusions

Simple, objective parameters from preoperative CT or MRCP images may help predict CR-POPF. Accurate risk assessment and early intervention may reduce complications and improve postoperative outcomes.

背景与目的:胰瘘(POPF)是胰十二指肠切除术(PD)后的严重并发症。准确预测临床相关POPF (CR-POPF)对于降低发病率至关重要。确定客观的、容易测量的术前危险因素可以改善患者的预后。因此,我们旨在确定CR-POPF的重要预测危险因素。方法:我们回顾性分析143例PD患者的资料。术前采用计算机断层扫描(CT)或磁共振胰胆管造影(MRCP)测量主胰管(MPD)直径、腹膜到胰腺前表面的距离(PTP)和腹壁厚度(AWT)。计算PTP/AWT比率作为内脏与皮下脂肪比率(V/S比率)的替代指标。同时评估肝脏与胰腺的平均CT衰减比(晚期/早期;L/E比)。进行单变量和多变量分析以确定CR-POPF的危险因素。结果:发生CR-POPF 33例(23.1%)。多变量分析确定V/S比≥3.5 (OR: 3.55, p = 0.041), L/E比。结论:术前CT或MRCP图像中简单、客观的参数可能有助于预测CR-POPF。准确的风险评估和早期干预可以减少并发症,改善术后预后。
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引用次数: 0
Correction to “A Comparative Analysis of Open Versus Minimally Invasive Pancreatoduodenectomies” 对“开放式与微创胰十二指肠切除术的比较分析”的更正。
IF 1.9 3区 医学 Q3 ONCOLOGY Pub Date : 2025-12-07 DOI: 10.1002/jso.70138

Valukas, C.S., Zaza, N.M., Vitello, D., Odell, D.D., Merkow, R. and Bentrem, D.J. (2025), A Comparative Analysis of Open Versus Minimally Invasive Pancreatoduodenectomies. Journal of Surgical Oncology, 131: 816-826. https://doi.org/10.1002/jso.27992

D. Bentrem was the Editor-in-Chief of the Journal of Surgical Oncology and simultaneously a coauthor of this article. Measures to manage this potential conflict of interest during the peer review process were not taken. Subsequently, both the peer review process and the content of the article were independently re-evaluated by the publisher's research integrity team. Despite any perceived conflict of interest, the publisher considers the results presented in this article to be reliable.

Valukas, c.s., Zaza, n.m., Vitello, D, Odell, d.d., Merkow, R.和Bentrem, D.J.(2025),开放与微创胰十二指肠切除术的比较分析。中华外科杂志,31:816-826。https://doi.org/10.1002/jso.27992D。Bentrem是《外科肿瘤学杂志》的主编,同时也是这篇文章的合著者。在同行评审过程中没有采取措施来管理这种潜在的利益冲突。随后,同行评议过程和文章内容都由出版商的研究诚信团队独立重新评估。尽管存在明显的利益冲突,但出版商认为本文提供的结果是可靠的。
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引用次数: 0
Correction to “Trends in Immunotherapy (Io) Use and Survival Among Patients With High-Incidence Stage IV Cancers Across the United States” 对“美国高发病率IV期癌症患者免疫治疗使用和生存趋势”的修正。
IF 1.9 3区 医学 Q3 ONCOLOGY Pub Date : 2025-12-07 DOI: 10.1002/jso.70141

Warwar, S. C., L. M. Janczewski, G. M. Rodriguez, J. D. Wayne, and D. J. Bentrem (2025), “Trends in Immunotherapy (IO) Use and Survival Among Patients With High-Incidence Stage IV Cancers Across the United States,” Journal of Surgical Oncology 131 (10): 1455–1466, https://doi.org/10.1002/jso.28084.

D. Bentrem was the Editor-in-Chief of the Journal of Surgical Oncology and simultaneously a coauthor of this article. Measures to manage this potential conflict of interest during the peer review process were not taken. Subsequently, both the peer review process and the content of the article were independently re-evaluated by the publisher's research integrity team. Despite any perceived conflict of interest, the publisher considers the results presented in this article to be reliable.

Warwar, S. C., L. M. Janczewski, G. M. Rodriguez, J. D. Wayne和D. J. Bentrem(2025),“免疫治疗(IO)在美国高发病率IV期癌症患者中的使用和生存趋势,外科肿瘤杂志131 (10):1455-1466,https://doi.org/10.1002/jso.28084.D。Bentrem是《外科肿瘤学杂志》的主编,同时也是这篇文章的合著者。在同行评审过程中没有采取措施来管理这种潜在的利益冲突。随后,同行评议过程和文章内容都由出版商的研究诚信团队独立重新评估。尽管存在明显的利益冲突,但出版商认为本文提供的结果是可靠的。
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引用次数: 0
Correction to “Current National Treatment Trends for Gastric Adenocarcinoma in the United States” 更正“当前美国国家胃腺癌治疗趋势”。
IF 1.9 3区 医学 Q3 ONCOLOGY Pub Date : 2025-12-07 DOI: 10.1002/jso.70139

Vitello, D. J., N. N. Zaza, K. R. Bates, L. M. Janczewski, G. Rodriguez, and D. J. Bentrem (2024), Current National Treatment Trends for Gastric Adenocarcinoma in the United States. Journal of Surgical Oncology 130 (10): 1563–1572. https://doi.org/10.1002/jso.27863.

D. Bentrem was the Editor-in-Chief of the Journal of Surgical Oncology and simultaneously a coauthor of this article. Measures to manage this potential conflict of interest during the peer review process were not taken. Subsequently, both the peer review process and the content of the article were independently re-evaluated by the publisher's research integrity team. Despite any perceived conflict of interest, the publisher considers the results presented in this article to be reliable.

Vitello, D. J, N. N. Zaza, K. R. Bates, L. M. Janczewski, G. Rodriguez和D. J. Bentrem(2024),美国胃腺癌的治疗趋势。肿瘤外科杂志,130(10):1563-1572。https://doi.org/10.1002/jso.27863.D。Bentrem是《外科肿瘤学杂志》的主编,同时也是这篇文章的合著者。在同行评审过程中没有采取措施来管理这种潜在的利益冲突。随后,同行评议过程和文章内容都由出版商的研究诚信团队独立重新评估。尽管存在明显的利益冲突,但出版商认为本文提供的结果是可靠的。
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引用次数: 0
Timing for Repair of Urosymphyseal Fistula After Diagnosis Determines the Incidence Postoperative Outcomes 诊断后尿联合瘘的修复时机决定了术后预后的发生率。
IF 1.9 3区 医学 Q3 ONCOLOGY Pub Date : 2025-12-07 DOI: 10.1002/jso.70133
Joseph M. Escandón, Lucas Kreutz-Rodrigues, Anthony E. Fadel, Jayson P. Kemble, James T. Paget, Matthew T. Houdek, Boyd Viers, Karim Bakri

Purpose

There is limited evidence regarding the optimal timing of urosymphyseal fistula (USF) repair. Our aim was to conduct a comparative analysis evaluating the postoperative complications and surgical outcomes among patients undergoing surgery for USF, comparing those treated in an early versus delayed fashion.

Methods

Fifty-eight patients with diagnosis of USF and who underwent fistula decompression, pubic bone resection, and urinary tract reconstruction were included. Patients who underwent USF repair within 100 days of diagnosis were classified as having early repair, while those treated after 100 days were considered to have delayed repair.

Results

Thirty-one underwent delayed USF repair (53.4%), while 27 underwent early repair (46.6%). Most patients were male (96.8%). The median age (72 years vs. 69 years, p = 0.13) and mean BMI (28.7 vs. 28.6, p = 0.97) were comparable between groups. The rate of overall 90-day complications following USF repair was comparable between groups (77.4% vs. 63%, p = 0.228). We did not find a difference between the rates early complications among groups. The rates of long-term recurrent pain (46.7% vs. 11.1%, p = 0.004), recurrent osteomyelitis (20% vs. 0%, p = 0.014), and fistula (23.3% vs. 3.7%, p = 0.033) were higher in the delayed USF repair group compared to the early USF repair group. The follow up time was similar between groups too (25.43-months vs. 32.8-months, p = 0.257).

Conclusion

While early USF repair might not affect the incidence of early complications within 90 days post-surgery, it is associated with reduced rates of long-term recurrent pain, recurrent osteomyelitis, and fistula recurrence compared to delayed USF repair.

目的:关于尿联合瘘(USF)修复的最佳时机的证据有限。我们的目的是进行一项比较分析,评估USF手术患者的术后并发症和手术结果,比较早期和延迟治疗的患者。方法:58例确诊为USF并行瘘管减压、耻骨切除、尿路重建的患者。诊断100天内接受USF修复的患者被归类为早期修复,而100天后接受治疗的患者被认为是延迟修复。结果:延迟修复31例(53.4%),早期修复27例(46.6%)。患者以男性居多(96.8%)。中位年龄(72岁对69岁,p = 0.13)和平均BMI(28.7对28.6,p = 0.97)组间具有可比性。两组间USF修复后90天总并发症发生率相当(77.4% vs. 63%, p = 0.228)。我们没有发现组间早期并发症发生率的差异。与早期USF修复组相比,延迟USF修复组的长期复发性疼痛(46.7%对11.1%,p = 0.004)、复发性骨髓炎(20%对0%,p = 0.014)和瘘管(23.3%对3.7%,p = 0.033)发生率更高。两组间随访时间相似(25.43个月vs 32.8个月,p = 0.257)。结论:虽然早期USF修复可能不会影响术后90天内早期并发症的发生率,但与延迟USF修复相比,它可以降低长期复发性疼痛、复发性骨髓炎和瘘复发率。
{"title":"Timing for Repair of Urosymphyseal Fistula After Diagnosis Determines the Incidence Postoperative Outcomes","authors":"Joseph M. Escandón,&nbsp;Lucas Kreutz-Rodrigues,&nbsp;Anthony E. Fadel,&nbsp;Jayson P. Kemble,&nbsp;James T. Paget,&nbsp;Matthew T. Houdek,&nbsp;Boyd Viers,&nbsp;Karim Bakri","doi":"10.1002/jso.70133","DOIUrl":"10.1002/jso.70133","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>There is limited evidence regarding the optimal timing of urosymphyseal fistula (USF) repair. Our aim was to conduct a comparative analysis evaluating the postoperative complications and surgical outcomes among patients undergoing surgery for USF, comparing those treated in an early versus delayed fashion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Fifty-eight patients with diagnosis of USF and who underwent fistula decompression, pubic bone resection, and urinary tract reconstruction were included. Patients who underwent USF repair within 100 days of diagnosis were classified as having early repair, while those treated after 100 days were considered to have delayed repair.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Thirty-one underwent delayed USF repair (53.4%), while 27 underwent early repair (46.6%). Most patients were male (96.8%). The median age (72 years vs<i>.</i> 69 years, <i>p</i> = 0.13) and mean BMI (28.7 vs<i>.</i> 28.6, <i>p</i> = 0.97) were comparable between groups. The rate of overall 90-day complications following USF repair was comparable between groups (77.4% vs<i>.</i> 63%, <i>p</i> = 0.228). We did not find a difference between the rates early complications among groups. The rates of long-term recurrent pain (46.7% vs<i>.</i> 11.1%, <i>p</i> = 0.004), recurrent osteomyelitis (20% vs<i>.</i> 0%, <i>p</i> = 0.014), and fistula (23.3% vs<i>.</i> 3.7%, <i>p</i> = 0.033) were higher in the delayed USF repair group compared to the early USF repair group. The follow up time was similar between groups too (25.43-months vs<i>.</i> 32.8-months, <i>p</i> = 0.257).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>While early USF repair might not affect the incidence of early complications within 90 days post-surgery, it is associated with reduced rates of long-term recurrent pain, recurrent osteomyelitis, and fistula recurrence compared to delayed USF repair.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":"133 2","pages":"217-225"},"PeriodicalIF":1.9,"publicationDate":"2025-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145701272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Practice Patterns Vary Among Orthopedic, Plastic, and General Surgeons Resecting Soft Tissue Tumors of the Extremities and Pelvis 实践模式在骨科、整形外科和普通外科医生中各不相同,切除四肢和骨盆的软组织肿瘤。
IF 1.9 3区 医学 Q3 ONCOLOGY Pub Date : 2025-11-30 DOI: 10.1002/jso.70147
Jon-Luc Poirier, Spencer M. Richardson, Adam M. Knox, L. Daniel Wurtz, Christopher D. Collier

Background

Resection of extremity soft tissue tumors is common and frequently performed by orthopedic, plastic, and general surgeons. It is unknown if tumor location, Preoperative workup, and Postoperative care varies by specialty, which is the aim of this study.

Methods

A retrospective review was performed of 4,223 soft tissue tumors resected from the extremities and pelvis within a large single-state health system between 2009 and 2019. A more detailed cross-sectional review was performed on 450 tumors resected in 2016. Demographic and tumor characteristics, surgeon specialty (orthopedic, plastic, general), Preoperative workup (imaging, biopsy), and Postoperative management were collected and analyzed.

Results

General surgeons were more likely to resect tumors superficial to fascia (82.1%), compared to plastic and orthopedic surgeons (53.7% and 27.9%). Orthopedic surgeons were more likely to resect malignant tumors (28.2%) than plastic and general surgeons (14.0% and 4.5%). 16.3% of tumors resected by general surgeons had either Preoperative MRI or tissue diagnosis, compared to 42.6% for plastic surgeons and 90.5% for orthopedic surgeons (p < 0.001). Of the tumors resected by general surgeons without Preoperative MRI or tissue diagnosis, 2.6% were malignant. Finally, Postoperative documentation of neurovascular status, range of motion, and referral to physical therapy were more likely performed by orthopedic surgeons (all p < 0.001).

Conclusion

Practice patterns vary significantly among orthopedic, plastic, and general surgeons treating soft tissue tumors of the extremities and pelvis. These findings highlight the need for multidisciplinary engagement and standardization of treatment algorithms and training practices across the various surgical specialties.

背景:肢体软组织肿瘤切除术是骨科、整形外科和普通外科医生经常进行的手术。目前尚不清楚肿瘤的位置、术前检查和术后护理是否因专科而异,这也是本研究的目的。方法:回顾性分析了2009年至2019年在大型单一州卫生系统中从四肢和骨盆切除的4223例软组织肿瘤。对2016年切除的450个肿瘤进行了更详细的横断面审查。收集和分析人口统计学和肿瘤特征、外科医生专业(骨科、整形、普通)、术前检查(影像学、活检)和术后处理。结果:普通外科医生切除筋膜浅表肿瘤的可能性(82.1%)高于整形外科医生(53.7%)和整形外科医生(27.9%)。整形外科医生切除恶性肿瘤的可能性(28.2%)高于整形外科医生和普通外科医生(14.0%和4.5%)。16.3%的普通外科医生切除的肿瘤术前有MRI或组织诊断,相比之下,整形外科医生为42.6%,整形外科医生为90.5% (p结论:整形外科医生、整形外科医生和普通外科医生治疗四肢和骨盆软组织肿瘤的实践模式差异很大。这些发现强调了跨不同外科专业的多学科参与和标准化治疗算法和培训实践的必要性。
{"title":"Practice Patterns Vary Among Orthopedic, Plastic, and General Surgeons Resecting Soft Tissue Tumors of the Extremities and Pelvis","authors":"Jon-Luc Poirier,&nbsp;Spencer M. Richardson,&nbsp;Adam M. Knox,&nbsp;L. Daniel Wurtz,&nbsp;Christopher D. Collier","doi":"10.1002/jso.70147","DOIUrl":"10.1002/jso.70147","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Resection of extremity soft tissue tumors is common and frequently performed by orthopedic, plastic, and general surgeons. It is unknown if tumor location, Preoperative workup, and Postoperative care varies by specialty, which is the aim of this study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective review was performed of 4,223 soft tissue tumors resected from the extremities and pelvis within a large single-state health system between 2009 and 2019. A more detailed cross-sectional review was performed on 450 tumors resected in 2016. Demographic and tumor characteristics, surgeon specialty (orthopedic, plastic, general), Preoperative workup (imaging, biopsy), and Postoperative management were collected and analyzed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>General surgeons were more likely to resect tumors superficial to fascia (82.1%), compared to plastic and orthopedic surgeons (53.7% and 27.9%). Orthopedic surgeons were more likely to resect malignant tumors (28.2%) than plastic and general surgeons (14.0% and 4.5%). 16.3% of tumors resected by general surgeons had either Preoperative MRI or tissue diagnosis, compared to 42.6% for plastic surgeons and 90.5% for orthopedic surgeons (<i>p</i> &lt; 0.001). Of the tumors resected by general surgeons without Preoperative MRI or tissue diagnosis, 2.6% were malignant. Finally, Postoperative documentation of neurovascular status, range of motion, and referral to physical therapy were more likely performed by orthopedic surgeons (all <i>p</i> &lt; 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Practice patterns vary significantly among orthopedic, plastic, and general surgeons treating soft tissue tumors of the extremities and pelvis. These findings highlight the need for multidisciplinary engagement and standardization of treatment algorithms and training practices across the various surgical specialties.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":"133 1","pages":"101-107"},"PeriodicalIF":1.9,"publicationDate":"2025-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12747694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145635076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two-Incision Approach for Internal Hemipelvectomy 双切口内半骨盆切除术。
IF 1.9 3区 医学 Q3 ONCOLOGY Pub Date : 2025-11-27 DOI: 10.1002/jso.70150
David Wilson, Michael Biddulph, Chad Coles, Ryan Trenholm
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引用次数: 0
期刊
Journal of Surgical Oncology
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