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Anxiety and Worry About COVID-19 Infection are Associated with Less Confidence in Ability to Engage in Treatment: Results from a South India Cohort of People Living with HIV (PLWH) 对新冠肺炎感染的焦虑和担忧与对治疗能力的信心下降有关:来自南印度艾滋病毒感染者队列的结果
Q3 INFECTIOUS DISEASES Pub Date : 2022-01-01 DOI: 10.1177/23259582221080303
M. Ekstrand, E. Heylen, Matilda Pereira, S. Chandy, K. Srinivasan
Following its initial outbreak in Wuhan in December 2019, SARS-CoV-2 spread rapidly around the world and was characterized byWHO as a global pandemic onMarch 12, 2020. Given its global impact, it led to a great deal of concern among the approximately 38 million people living with HIV (PWH). Although many governments worked hard to sustain HIV services, often in collaboration with community partners, it soon became clear that PWH faced multiple barriers and challenges to remain engaged in the HIV care continuum. Containment of the global COVID-19 pandemic required that governments implemented multiple strategies, including requirements to shelter-in-place, distancing, and placing restrictions on travel, which may serve as barriers to accessing non-COVID-related healthcare. OnMarch 25, 2020, the government of India announced an initial “lockdown,” due to the global COVID-19 pandemic, which restricted movement, social gatherings and economic activity until May 31. This resulted in many citizens returning to their native homes to shelter with their extended families. It is unknown what impact the lockdowns may have had on the ability of PWH to visit ART clinics, obtain prescription refills or adhere to their regimens. Since successfulmanagement of HIV requires excellent adherence and timely prescription refills to avoid treatment interruptions, real or perceived challenges, including HIV stigma and worries about coronavirus infection may have interfered with this effort.
继2019年12月在武汉首次爆发后,严重急性呼吸系统综合征冠状病毒2型在世界各地迅速传播,并于2020年3月12日被世卫组织定性为全球大流行。鉴于其全球影响,它引起了约3800万艾滋病毒感染者的极大关注。尽管许多政府经常与社区合作伙伴合作,努力维持艾滋病毒服务,但很快就清楚,PWH在继续参与艾滋病毒护理工作方面面临着多重障碍和挑战。遏制全球新冠肺炎大流行需要各国政府实施多项战略,包括要求就地避难、保持距离和限制旅行,这可能会成为获得非新冠肺炎相关医疗保健的障碍。2020年3月25日,印度政府宣布了最初的“封锁”,原因是全球新冠肺炎疫情限制了行动、社交聚会和经济活动,直到5月31日。这导致许多公民返回家乡,与他们的大家庭一起避难。目前尚不清楚封锁可能对PWH访问ART诊所、获得处方补充或坚持其治疗方案的能力产生了什么影响。由于成功管理艾滋病毒需要良好的依从性和及时的处方补充,以避免治疗中断,包括艾滋病毒污名化和对冠状病毒感染的担忧在内的真实或感知的挑战可能干扰了这一努力。
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引用次数: 3
HIV Related Stigma among Healthcare Providers: Opportunities for Education and Training. 医疗保健提供者中与艾滋病毒相关的耻辱:教育和培训的机会。
Q3 INFECTIOUS DISEASES Pub Date : 2022-01-01 DOI: 10.1177/23259582221114797
Amanda Blair Spence, Cuiwei Wang, Katherine Michel, Joanne Michelle Ocampo, Michael Kharfen, Daniel Merenstein, Lakshmi Goparaju, Seble Kassaye

Background: HIV-stigma can influence engagement in care and viral suppression rates among persons living with HIV (PLWH). Understanding HIV-provider level stigma and its associated factors may aid in development of interventions to improve engagement in care. Methods: We assessed HIV-related stigma, provider knowledge, and practices and beliefs among healthcare providers using an online survey tool. Generalized linear modeling was used to determine factors associated with HIV-stigma score. Results: Among 436 participants, the mean age was 42.3 (SD 12.3), 70% female, 62% white, 65% physicians, and 44% worked at an academic center. The mean HIV Health Care Provider Stigma Scale (HPASS) score was 150.5 (SD 18.9, total = 180 [higher score = less stigma]) with factor subscale scores of 67.1 (SD 8.2, total = 78) prejudice, 51.3 (SD 9.7, total = 66) stereotyping, and 32.1 (SD 5, total = 36) discrimination. Female sex and comfort with talking about sex and drug use had 4.97 (95% CI 0.61, 9.32) and 1.99 (95% CI 0.88, 3.10) estimated higher HPASS scores. Disagreement/strong disagreement versus strong agreement with the statement that PLWH should be allowed to have babies and feeling responsible for talking about HIV prevention associated with -17.05 (95% CI -25.96, -8.15) and -2.16 (95% CI -3.43, -0.88) estimated lower HPASS scores. Conclusions: The modifiable factors we identified as associated with higher HIV related stigma may provide opportunities for education that may ameliorate these negative associations.

背景:艾滋病毒耻辱感可以影响艾滋病毒感染者(PLWH)参与护理和病毒抑制率。了解艾滋病毒提供者水平的耻辱及其相关因素可能有助于制定干预措施,以提高对护理的参与度。方法:我们使用在线调查工具评估艾滋病毒相关的耻辱,提供者知识,以及医疗保健提供者的做法和信念。采用广义线性模型确定与hiv污名评分相关的因素。结果:在436名参与者中,平均年龄为42.3岁(SD 12.3), 70%为女性,62%为白人,65%为医生,44%在学术中心工作。HIV卫生保健提供者污名量表(HPASS)平均得分为150.5分(SD 18.9,总= 180[得分越高=污名越少]),因子子量表得分为偏见67.1分(SD 8.2,总= 78),刻板印象51.3分(SD 9.7,总= 66),歧视32.1分(SD 5,总= 36)。女性的性行为以及谈论性和吸毒的舒适度分别有4.97 (95% CI 0.61, 9.32)和1.99 (95% CI 0.88, 3.10)的HPASS评分较高。不同意/强烈不同意与强烈同意的说法,即应该允许艾滋病毒携带者生孩子,并感到有责任谈论艾滋病毒预防,与-17.05 (95% CI -25.96, -8.15)和-2.16 (95% CI -3.43, -0.88)相关的HPASS评分估计较低。结论:我们确定的与HIV相关的更高的耻辱感相关的可修改因素可能为改善这些负面关联的教育提供机会。
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引用次数: 3
Depression and Anxiety in Youth and Young Adults Living with HIV: Frequency and Associated Factors in Thai Setting 艾滋病毒感染青年和年轻人的抑郁和焦虑:泰国环境中的频率和相关因素
Q3 INFECTIOUS DISEASES Pub Date : 2022-01-01 DOI: 10.1177/23259582221101811
S. Chantaratin, Kawita Trimetha, P. Werarak, K. Lapphra, Alan Maleesatharn, S. Rungmaitree, O. Wittawatmongkol, W. Phongsamart, N. Kongstan, Benjawan Khumcha, K. Chokephaibulkit
Integrative mental health care in HIV patients is an important contributor to successful therapy. This is a cross-sectional study in youth and young adults who attend routine HIV clinic at a tertiary care centre in Bangkok. We recruited 100 youth and 130 young adults living with HIV to evaluate the frequency of depression and anxiety and associated sociodemographic including sexual orientation and health-related behaviours. Overall, about a fifth of the participants had significant depression or anxiety. Interestingly, we found different factors associated with depression in youth and young adults living with HIV. Loss of their father, loss of close relatives or friends, and being unemployed or school exclusion were the factors associate with depression in youth; while dangerous alcohol use, feeling discriminated against and having lipodystrophy were factors in young adults. The understanding of the frequency and different associated factors can inform more effective prevention and treatment strategies.
艾滋病毒患者的综合心理保健是治疗成功的重要因素。这是一项在曼谷三级保健中心参加常规艾滋病毒诊所的青年和年轻人的横断面研究。我们招募了100名青少年和130名感染艾滋病毒的年轻人来评估抑郁和焦虑的频率以及相关的社会人口统计,包括性取向和与健康相关的行为。总的来说,大约五分之一的参与者有明显的抑郁或焦虑。有趣的是,我们在感染艾滋病毒的青少年和年轻人中发现了与抑郁相关的不同因素。失去父亲、失去亲人或朋友、失业或被学校排斥是导致青少年抑郁的因素;而危险饮酒、感觉受到歧视和脂肪营养不良是影响年轻人健康的因素。了解频率和不同的相关因素可以为更有效的预防和治疗策略提供信息。
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引用次数: 3
Efficacy and Safety of Bictegravir-Based Regimen in Pregnant Women Living with HIV: A Case Report. 以比替格韦为基础的方案治疗HIV感染孕妇的疗效和安全性:1例报告。
Q3 INFECTIOUS DISEASES Pub Date : 2022-01-01 DOI: 10.1177/23259582221146110
Shaimaa Alsulami, Sultan N Alotaibi, Nader Damfu, Doaa M Aljefri, Hadeel Ahmed Altayib, Maher Alharbi

Bictegravir (BIC) is included in international guidelines as the first line of therapy for patients living with Human Immunodeficiency Virus (HIV), either as initial therapy or as a replacement for patients with prior antiretroviral therapy (ART). Due to limited efficacy and safety data, BIC is currently not recommended during pregnancy. Data on the safety and efficacy of BIC during pregnancy were unavailable at the time of drug approval. In our case, BIC/TAF/FTC was effective in suppressing viral load (VL) in pregnancy, and there were no reported safety issues for the mother or the baby.

Bictegravir (BIC)被列入国际指南,作为人类免疫缺陷病毒(HIV)患者的第一线治疗,可作为初始治疗或替代先前接受抗逆转录病毒治疗(ART)的患者。由于有效性和安全性数据有限,目前不建议在怀孕期间使用BIC。在药物批准时,关于妊娠期间BIC的安全性和有效性的数据是不可获得的。在我们的病例中,BIC/TAF/FTC在抑制妊娠期病毒载量(VL)方面是有效的,并且没有报告对母亲或婴儿的安全问题。
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引用次数: 0
Impact of Antiretroviral Therapy on Kidney Disease in HIV Infected Individuals – A Qualitative Systematic Review 抗逆转录病毒治疗对HIV感染者肾脏疾病的影响——一项定性系统评价
Q3 INFECTIOUS DISEASES Pub Date : 2022-01-01 DOI: 10.1177/23259582221089194
Harsha Adnani, Nirav Agrawal, A. Khatri, Jaclyn Vialet, Meng Zhang, J. Cervia
Kidney disease is the fourth most common cause of non-AIDS-related mortality in people living with HIV. Combination antiretroviral therapy (cART) remains the cornerstone of treatment. However, little is known about the impact of cART on disease outcomes in patients with HIV-associated nephropathy (HIVAN) and HIV-immune complex kidney disease (HIVICK). This systematic review evaluates the impact of cART on progression to end-stage kidney disease (ESKD) and other outcomes in HIV-infected individuals. We conducted a literature search utilizing PubMed, and Cochrane database and 11 articles met inclusion criteria for analysis of which nine HIVAN studies showed decreased progression to ESKD or death for subjects when treated with cART versus those untreated. However, two studies showed no survival advantage with cART. Three HIVICK studies showed improvement in delaying ESKD in subjects on cART compared to untreated subjects. cART appeared to reduce the risk to ESKD or death in patients with both HIVAN and HIVICK.
肾脏疾病是艾滋病毒感染者非艾滋病相关死亡的第四大常见原因。联合抗逆转录病毒疗法(cART)仍然是治疗的基石。然而,cART对hiv相关肾病(HIVAN)和hiv免疫复杂肾病(HIVICK)患者疾病结局的影响知之甚少。本系统综述评估了cART对hiv感染者进展为终末期肾病(ESKD)和其他结局的影响。我们利用PubMed和Cochrane数据库进行了文献检索,11篇文章符合纳入标准,其中9篇HIVAN研究显示,与未治疗的受试者相比,接受cART治疗的受试者进展为ESKD或死亡减少。然而,两项研究显示cART没有生存优势。三项HIVICK研究显示,与未治疗的受试者相比,cART患者延迟ESKD有所改善。cART似乎可以降低HIVAN和HIVICK患者发生ESKD或死亡的风险。
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引用次数: 2
Adherence to Antiretroviral Therapy and Associated Factors Among People Living With HIV Following the Introduction of Dolutegravir Based Regimens in Dar es Salaam, Tanzania 在坦桑尼亚达累斯萨拉姆引入以多替格拉韦为基础的治疗方案后,艾滋病毒感染者坚持抗逆转录病毒治疗及其相关因素
Q3 INFECTIOUS DISEASES Pub Date : 2022-01-01 DOI: 10.1177/23259582221084543
Mary Spicar Kilapilo, Raphael Zozimus Sangeda, G. Bwire, G. Sambayi, I. Mosha, J. Killewo
Background: Adherence to antiretroviral therapy (ART) is the key determinant of virological suppression in people living with HIV (PLHIV). This study reports factors associated with non-adherence among PLHIV one year after introducing dolutegravir (DTG) based regimens in Tanzania. Methods: A hospital-based cross-sectional study was conducted in two health facilities in Dar es Salaam, Tanzania, in 2020. Results: A total of 406 PLHIV were recruited, where the majority (73.4%) were females, with 94.6% of patients being on DTG based regimens. Factors such as refill interval and sharing of antiretrovirals had significant effects on adherence. Multivariate analysis found that patients attending care and treatment center (CTC) at Temeke Regional Referral Hospital (RRH) were 4.3 times more likely to have non-adherence compared to those attending Amana RRH (aOR [adjusted odds ratio] 4.3, 95% CI [confidence interval]: 2.38 – 7.91, p-value < 0.0001). Conclusions: Sustainable adherence counseling is warranted to overcome non-adherence to ART.
背景:坚持抗逆转录病毒治疗(ART)是HIV感染者(PLHIV)病毒学抑制的关键决定因素。本研究报告了在坦桑尼亚引入多替格拉韦(DTG)治疗方案一年后与PLHIV患者不依从性相关的因素。方法:2020年在坦桑尼亚达累斯萨拉姆的两家卫生机构进行了一项以医院为基础的横断面研究。结果:共招募了406名PLHIV患者,其中大多数(73.4%)为女性,其中94.6%的患者使用基于DTG的方案。诸如补充间隔和共享抗逆转录病毒药物等因素对依从性有显著影响。多因素分析发现,在Temeke地区转诊医院(RRH)护理和治疗中心(CTC)就诊的患者发生不依从的可能性是在Amana RRH就诊的患者的4.3倍(aOR[调整优势比]4.3,95% CI[置信区间]:2.38 ~ 7.91,p值< 0.0001)。结论:持续的依从性咨询是必要的,以克服不坚持抗逆转录病毒治疗。
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引用次数: 2
Social Network Strategy to Promote HIV Testing and Linkage to HIV Services among Young men who Have sex with men and Transgender Women in Thailand. 促进泰国男男性行为青年和变性妇女艾滋病毒检测和与艾滋病毒服务联系的社会网络战略。
Q3 INFECTIOUS DISEASES Pub Date : 2022-01-01 DOI: 10.1177/23259582221143672
Nantika Paiboon, Wipaporn Natalie Songtaweesin, Prissana Wongharn, Jutamanee Moonwong, Sasiprapha Khamthi, Athiporn Premgamone, Tuangtip Theerawit, Chutima Saisaengjan, Surinda Kawichai, Suvaporn Anugulruengkitt, Thanyawee Puthanakit

Background: Social network strategies (SNS) assumes that people in the same social share similar HIV risk. Methods: This study evaluated SNS to promote HIV testing of young men who have sex with men (YMSM) and transgender women (YTGW) aged 15-24 years. "Recruiters" referred their 'network members' (NMs) to clinic. NMs were provided HIV testing. Proportions of first-time HIV testers and number of NMs were analyzed. Results: Between April 2021 to March 2022, 83 recruiters referred 202 NMs. Median age of NMs was 19 years (IQR 17-20), 62% were YMSM. One-hundred-and-twenty-four NMs (61%) were first-time HIV testers. YTGW recruited more NMs per recruiter (5.4 vs 1.4, p  =  0.002). HIV prevalence was 3.0% (95% CI 1.1-6.4). Thirty-one-point-three percent of NMs at HIV risk initiated oral HIV preexposure prophylaxis. Conclusions: SNS is a good strategy to reach adolescents at risk of HIV infection. More than half of NMs were first-time HIV testers.

背景:社交网络策略(SNS)假设同一社会中的人们具有相似的HIV风险。方法:本研究评估社交媒体对15-24岁年轻男男性行为者(YMSM)和跨性别女性(YTGW) HIV检测的促进作用。“招聘人员”将他们的“网络成员”(NMs)介绍给诊所。为护士提供艾滋病毒检测。分析首次检测HIV的比例和NMs的数量。结果:在2021年4月至2022年3月期间,83名招聘人员推荐了202个NMs。NMs的中位年龄为19岁(IQR 17-20), 62%为YMSM。124名NMs(61%)是首次进行HIV检测。YTGW招聘了更多的经理(5.4 vs 1.4, p = 0.002)。HIV患病率为3.0% (95% CI 1.1-6.4)。有艾滋病毒风险的NMs中有31.3%开始口服艾滋病毒暴露前预防。结论:社交网络是接触艾滋病毒感染高危青少年的良好策略。半数以上的女性是第一次接受艾滋病毒检测。
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引用次数: 1
Corticosteroids Use and Incidence of Severe Infections in People Living with HIV Compared to a Matched Population 与匹配人群相比,艾滋病毒感染者皮质类固醇的使用和严重感染的发生率
Q3 INFECTIOUS DISEASES Pub Date : 2022-01-01 DOI: 10.1177/23259582221107196
J. Damba, M. Laskine, Marc-Messier Peet, Yulan Jin, L. Sinyavskaya, Madeleine Durand
Background: People living with HIV (PLWH) have been shown to have an increased risk of autoimmune diseases. Corticosteroids are the cornerstone of autoimmune diseases treatment, but their use is associated with an increased risk of infections. It is unclear how HIV status affects the risk of infection associated with corticosteroids use. Methods: We conducted a retrospective cohort study from 1991 to 2011, using a medico-administrative database from Quebec. Medical billing codes were used to identify PLWH, and we matched them on age, sex, and index date with up to 4 HIV-negative controls. The exposure of interest was the use of corticosteroids, defined as a systemic corticosteroid dispensation lasting at least 20 days. The outcome of interest was hospitalization for severe infection. Crude and adjusted incidence rates ratios of infection were obtained using a random effect Poisson model, and results were stratified by HIV status. Results: In total, 4798 PLWH were matched to 17 644 HIV-negative controls, among which 1083 (22.6%) PLWH and 1854 (10.5%) HIV-negative controls received at least one course of corticosteroid. The mean duration of corticosteroids use was 4 ± 4.4 months in PLWH and 1.6 ± 5.5 months in HIV-negative controls. The incidence rate ratio (IRR) for infections associated with corticosteroids use was 2.49[1.71–3.60] in PLWH and 1.32[0.71–2.47] in HIV-negative controls (P value for interaction 0.18). The most frequent infections were pulmonary infections (50.4%), followed by urinary tract infections (26%) and opportunistic infections (10.5%). Conclusion: Although our interaction term did not reach significance, the increased risk of infection associated with corticosteroids use was more pronounced in PLWH. However, further research with contemporary data is warranted to confirm if the risk associated with corticosteroids use remains high in PLWH with well-controlled HIV infection.
背景:HIV感染者(PLWH)患自身免疫性疾病的风险增加。皮质类固醇是自身免疫性疾病治疗的基石,但它们的使用会增加感染风险。目前尚不清楚HIV状态如何影响与使用皮质类固醇相关的感染风险。方法:我们使用魁北克省的医疗管理数据库,从1991年到2011年进行了一项回顾性队列研究。医疗账单代码用于识别PLWH,我们将其与多达4名HIV阴性对照在年龄、性别和索引日期上进行匹配。感兴趣的暴露是皮质类固醇的使用,定义为持续至少20天的全身皮质类固醇分配。感兴趣的结果是因严重感染住院治疗。使用随机效应泊松模型获得感染的粗略和调整后的发病率比率,并根据HIV状况对结果进行分层。结果:总共4798个PLWH与17个匹配 644名HIV阴性对照,其中1083名(22.6%)PLWH和1854名(10.5%)HIV阴性对照接受了至少一个疗程的皮质类固醇治疗。皮质类固醇使用的平均持续时间为4 ± PLWH 4.4个月和1.6个月 ± HIV阴性对照组5.5个月。与使用皮质类固醇相关的感染的发病率比率(IRR)在PLWH中为2.49[1.71-3.60],在HIV阴性对照中为1.32[0.71-2.47](相互作用的P值为0.18)。最常见的感染是肺部感染(50.4%),其次是尿路感染(26%)和机会性感染(10.5%)。结论:尽管我们的相互作用项没有达到显著意义,但与使用皮质类固醇相关的感染风险增加在PLWH中更为明显。然而,有必要对当代数据进行进一步研究,以确认在HIV感染得到良好控制的PLWH中,使用皮质类固醇的风险是否仍然很高。
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引用次数: 2
Oral Abstracts from the Fast-Track Cities 2021 Conference Lisbon Portugal October 20-22, 2021 葡萄牙里斯本2021年快速通道城市会议口头摘要2021年10月20日至22日
Q3 INFECTIOUS DISEASES Pub Date : 2022-01-01 DOI: 10.1177/23259582221075431
Johnathan Saffold, P. Seal, M. Clement, Kevin Hemenger, Andrew Santiago, Kelly Muzariri, Collin, Mangenah, Tawanda Dadirai, Phyllis, Magoge-Mandizvidza, Rufurwokuda Maswera, C. Nyamukapa, K. Hauck, Simon, Gregson, M. Pickles, E. Valverde, Bordalo Mouzinho
Results: The results are shown as RW/private, respectively. Median age was 30/29. MSM/TF was 84.5/83%. Median baseline CD4 was 421/401 cells/mm3. Median HIV RNA was 46,394/74,500 copies/ml. Median days from diagnosis to ART were 13/4. Median days from diagnosis to viral suppression (VS) were 55/47, and ART to VS were 35/42. When comparing the RW clinic’s data to its historical data, days from diagnosis to VS decreased from 27.5 to 13 days (p-value 0.0001), and days from ART to VS decreased from 55 to 35 days (p-value 0.0002). Retention in care at 6 months were 72.5/97%, respectively. Retention in care at 12 months with at least one VS was 92.6/95%. Retention in care at 18 months was 70.3/82%. Retention in care at 24 months was 73.5/94%. Retention in care at 24 months with at least one VS was 72.8/84%.
结果:结果分别显示为RW/private。中位年龄为30/29岁。MSM/TF为84.5/83%。中位基线CD4为421/401细胞/mm3。HIV RNA的中位数为46394/74500拷贝/ml。从诊断到ART的中位天数为13/4天。从诊断到病毒抑制(VS)的中位天数为55/47,ART到VS的中位日期为35/42。当将RW诊所的数据与其历史数据进行比较时,从诊断到VS的天数从27.5天减少到13天(p值0.0001),从ART到VS的时间从55天减少到35天(p值0.0002)。6个月时的护理保留率分别为72.5/97%。至少有一个VS的12个月护理保留率为92.6/95%。18个月护理保持率为70.3/82%。24个月护理保存率为73.5/94%。至少有一次VS的24个月治疗保留率为72.8/84%。
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引用次数: 0
Undernutrition and Associated Risk Factors among Adult HIV/AIDS Patients Attending Antiretroviral Therapy at Public Hospitals of Bench Sheko Zone, Southwest Ethiopia. 埃塞俄比亚西南部Bench Sheko区公立医院接受抗逆转录病毒治疗的成年艾滋病毒/艾滋病患者的营养不良及相关危险因素
Q3 INFECTIOUS DISEASES Pub Date : 2022-01-01 DOI: 10.1177/23259582221079154
Nigusie Shifera, Tewodros Yosef, Rahel Matiyas, Ayechew Kassie, Ashenafi Assefa, Abebaw Molla

Even though there are advancements in the treatment of patients with HIV, many deaths are related to undernutrition. Despite this fact, the burden of undernutrition and associated factors among adults receiving ART is a significant shortcoming in the study area. A cross-sectional study was done in public hospitals of the Bench-Sheko zone. Face-to-face interviews were used to gather information. Odds ratio with a 95% confidence level was used to identify determinants of undernutrition. The proportion of undernutrition, normal, and overweight were 29.2%, 61.2%, and 9.6% respectively. Food insecurity, poor ART adherence, low CD4 count, and substance use were factors associated with under nutrition among HIV patients. Undernutrition was so high in comparison to other studies in Ethiopia; the local concerned bodies should focus on identified risk factors for improving HIV/AIDS treatment via health education, nutritional assistance and counseling.

尽管在治疗艾滋病毒患者方面取得了进展,但许多死亡与营养不良有关。尽管如此,在接受抗逆转录病毒治疗的成年人中,营养不良和相关因素的负担是该研究领域的一个重大缺陷。横断面研究在Bench-Sheko地区的公立医院进行。面对面的访谈被用来收集信息。使用95%置信水平的优势比来确定营养不良的决定因素。营养不良、正常和超重的比例分别为29.2%、61.2%和9.6%。粮食不安全、抗逆转录病毒治疗依从性差、CD4细胞计数低和药物使用是与艾滋病毒患者营养不良相关的因素。与埃塞俄比亚的其他研究相比,营养不良是如此之高;地方有关机构应通过健康教育、营养援助和咨询,集中注意已查明的危险因素,以改善艾滋病毒/艾滋病的治疗。
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引用次数: 0
期刊
Journal of the International Association of Providers of AIDS Care
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