Journal of the National Medical Association最新文献_第2页

Addressing visual learning equity in undergraduate dermatology education: Skin color representation across dermatology lecture images at Rutgers New Jersey Medical School

IF 2.5 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Journal of the National Medical Association

Pub Date : 2025-02-01 DOI: 10.1016/j.jnma.2025.01.010

Rucha Janodia , Helen Nguyen , Valerie A. Fitzhugh , Christin Traba , Sophia Chen , Jeremy J. Grachan

Minimally-melanated skin has been the standard for dermatologic education. Research has shown that the lack of brown and black images in dermatologic medical education may contribute to unequal early recognition of diseases across different skin types. Promoting visual equity in educational resources throughout undergraduate medical education may allow for students to improve their confidence in identifying skin lesions in patients of color. Dermatology lectures at Rutgers New Jersey Medical School (NJMS) were examined using the New Immigrant Survey (NIS) Skin Color Scale. Four pre-clerkship lectures featuring various skin lesions were analyzed and images were categorized as light/white, medium/brown, and dark/black skin types. The light/white skin category was the most heavily represented accounting for 59.5 % (n = 185) of all images across the four lectures, medium/brown skin type accounted for 16.1 % (n = 50), and dark/black skin type was 24.4 % (n = 76). Across the four lectures, there were 109 dermatologic conditions covered. Of the 109, 35 (32 %) only included images from one skin tone, which was usually light/white skin, whereas 17 (16 %) included images of all three skin types. INSTITUTION is located in Newark, New Jersey a diverse community with 48.2 % of its residents identifying as Black/African American and 36.8 % identifying as Hispanic/Latino in 2022. Currently, there have been efforts at INSTITUTION to promote visual learning equity, especially to represent the community it resides in. Addressing this disparity in medical education is a vital step toward achieving more equitable healthcare practices and outcomes for patients.

{"title":"Addressing visual learning equity in undergraduate dermatology education: Skin color representation across dermatology lecture images at Rutgers New Jersey Medical School","authors":"Rucha Janodia , Helen Nguyen , Valerie A. Fitzhugh , Christin Traba , Sophia Chen , Jeremy J. Grachan","doi":"10.1016/j.jnma.2025.01.010","DOIUrl":"10.1016/j.jnma.2025.01.010","url":null,"abstract":"<div><div>Minimally-melanated skin has been the standard for dermatologic education. Research has shown that the lack of brown and black images in dermatologic medical education may contribute to unequal early recognition of diseases across different skin types. Promoting visual equity in educational resources throughout undergraduate medical education may allow for students to improve their confidence in identifying skin lesions in patients of color. Dermatology lectures at Rutgers New Jersey Medical School (NJMS) were examined using the New Immigrant Survey (NIS) Skin Color Scale. Four pre-clerkship lectures featuring various skin lesions were analyzed and images were categorized as light/white, medium/brown, and dark/black skin types. The light/white skin category was the most heavily represented accounting for 59.5 % (<em>n</em> = 185) of all images across the four lectures, medium/brown skin type accounted for 16.1 % (<em>n</em> = 50), and dark/black skin type was 24.4 % (<em>n</em> = 76). Across the four lectures, there were 109 dermatologic conditions covered. Of the 109, 35 (32 %) only included images from one skin tone, which was usually light/white skin, whereas 17 (16 %) included images of all three skin types. INSTITUTION is located in Newark, New Jersey a diverse community with 48.2 % of its residents identifying as Black/African American and 36.8 % identifying as Hispanic/Latino in 2022. Currently, there have been efforts at INSTITUTION to promote visual learning equity, especially to represent the community it resides in. Addressing this disparity in medical education is a vital step toward achieving more equitable healthcare practices and outcomes for patients.</div></div>","PeriodicalId":17369,"journal":{"name":"Journal of the National Medical Association","volume":"117 1","pages":"Pages 74-79"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Racial disparities in osteoarthritis: Prevalence, presentation, and management in the United States

IF 2.5 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Journal of the National Medical Association

Pub Date : 2025-02-01 DOI: 10.1016/j.jnma.2025.01.007

Youssef Abdullah , Olayemi O. Olubowale , Kevin V. Hackshaw

Osteoarthritis (OA) is the most common form of arthritis in the United States, affecting approximately 24 % of adults. This literature review aims to summarize racial and ethnic disparities in OA prevalence, presentation, disability, diagnosis, and management among different groups in the U.S. The review found significant disparities, particularly affecting African Americans (AAs) and Hispanics (HISs) compared to non-Hispanic whites (WHs). AAs showed higher odds of developing symptomatic and radiological knee OA, with more severe radiological features. Pain and disability due to OA were also more pronounced in AAs and HISs. Disparities extended to imaging workup, with AAs less likely to undergo hip X-rays and MRIs for hip OA. Management strategies, including physical therapy, pharmacological treatments, and surgical interventions, were less utilized by AAs and HISs compared to WHs. These disparities are influenced by complex, multifaceted factors including socioeconomic status, education level, and healthcare access. The review highlights the urgent need for targeted interventions and policy changes to address these racial-ethnic disparities in OA care and outcomes.

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引用次数: 0

A cross sectional analysis of residents by race/ethnicity and specialty from 2020-2023 对 2020-2023 年按种族/族裔和专业分列的住院医师进行横截面分析。

IF 2.5 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Journal of the National Medical Association

Pub Date : 2024-12-01 DOI: 10.1016/j.jnma.2024.10.006

William H. Swain , Alec J. Calac , Luis R. Gasca , Benjamin R. Harris , Alice Gallo de Moraes

Background

Minorities are underrepresented in all areas of medical education relative to the United States general population, and minority physicians are more likely to practice in disadvantaged areas and in primary care settings. Many individual and structural factors contribute to this discrepancy. We aimed to demonstrate how resident race/ethnicity representation differs across the various resident specialties.

Methods

We used publically available data from the Association of American Medical College's Report on Residents data series and averaged the four academic years from 2019 to 2020 through 2022-2023. We then calculated the odds ratio (OR) of self-reported race/ethnicity (alone and in combination) in thirty-four specialties.

Results

Across the four-year study period, there were, on average, 147026 unduplicated resident trainees. The average number of duplicated residents by self-identified ethnic category (alone and in combination) include: American Indian or Alaska Native (839, 0.6%), Asian (31627, 21.5%), Black or African American (7935, 5.4%), Hispanic, Latino, or of Spanish Origin (10900, 7.4%), Native Hawaiian or Other Pacific Islander (296, 0.2%), White (76289, 51.9%), Other (4879, 3.3%), Unknown (522, 0.4%), and Non-US Citizens (23914, 16.3%). Across race/ethnicity, there are differences in ORs of representation in different specialties. Key findings include high representation in Public Health and Preventative Medicine by Black and African American (OR=3.7) and Native Hawaiian (OR=2.6) residents, and Family Medicine in Native Americans (OR=1.9), Native Hawaiian (OR=1.7), Black (OR=1.5), and Hispanic (OR=1.3) residents. Psychiatry also had high ORs of representation in minority residents.

Conclusion

This study illustrates relative resident ethnic representation across training specialties. Minorities ethnicities were more likely to be represented in primary care and public health domains. This has implications for creating a physician workforce suitable to serve the United States Population.

背景：与美国总人口相比，少数族裔在医学教育的各个领域都代表性不足，少数族裔医生更有可能在贫困地区和初级医疗机构执业。许多个人和结构性因素造成了这种差异。我们的目的是展示不同住院医师专业的住院医师种族/族裔代表性有何不同：我们使用了美国医学院协会《住院医师报告》数据系列中的公开数据，并对 2019-2020 年至 2022-2023 年四个学年的数据进行了平均。然后，我们计算了三十四个专业中自我报告的种族/民族（单独和组合）的几率比（OR）：在四年的研究期间，平均有 147026 名不重复的住院医师学员。按自我认定的种族类别（单独和组合）分列的重复住院医师平均人数包括美国印第安人或阿拉斯加原住民（839，0.6%）、亚裔（31627，21.5%）、黑人或非裔美国人（7935，5.4%）、西班牙裔、拉丁裔或西班牙血统（10900，7.4%）、夏威夷原住民或其他太平洋岛民（296，0.2%）、白人（76289，51.9%）、其他（4879，3.3%）、未知（522，0.4%）和非美国公民（23914，16.3%）。不同种族/族裔在不同专业的代表性指数存在差异。主要发现包括：公共卫生和预防医学的黑人和非裔美国人（OR=3.7）和夏威夷原住民（OR=2.6）住院医师比例较高；家庭医学的美国原住民（OR=1.9）、夏威夷原住民（OR=1.7）、黑人（OR=1.5）和西班牙裔（OR=1.3）住院医师比例较高。精神病学在少数民族住院医师中也有较高的代表性：本研究说明了各培训专科住院医师的相对种族代表性。少数民族在初级保健和公共卫生领域的代表性更高。这对建立一支适合为美国人口服务的医生队伍具有重要意义。

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引用次数: 0

Insights on oral health, heart disease, COPD and diabetes with important information on minority representation in health care workforce 对口腔健康、心脏病、慢性阻塞性肺病和糖尿病的见解，以及关于卫生保健工作人员中少数民族代表性的重要信息。

IF 2.5 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Journal of the National Medical Association

Pub Date : 2024-12-01 DOI: 10.1016/j.jnma.2024.11.002

Marie L. Borum MD, EdD, MPH, MACP, FACG, AGAF, FRCP

引用次数: 0

Sickle cell disease: Contributing factors and radiological assessments 镰状细胞病：影响因素和放射学评估。

IF 2.5 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Journal of the National Medical Association

Pub Date : 2024-12-01 DOI: 10.1016/j.jnma.2023.05.004

Gail Cherry-Peppers , Cheryl Fryer , Andrea D. Jackson , Xinbin Gu , Debra Ford , Alison Glascoe , Dawn Smith , Meirong Liu , Jacquelyn Dunmore-Griffith , Gillian Robinson-Warner , Crystal McIntosh , Jezelle Sonnier , Lisa Slade , Adel Rizkalla , Shakeya Mundey , Nyree Dawson , Manouchka Fleurinord , Baron Edmonson , Courtney Ford , Jillian Griffith , Terri Watkins-Bryant

Sickle Cell Disease (SCD) is genetically described as an autosomal blood disorder resulting from the presence of a mutated form of hemoglobin. Morbidity, frequency of crisis, degree of anemia, and organ systems involved vary considerably per patient. Dental health professionals and other specialists commonly request comprehensive medical consultations prior to performing complex periodontal, endodontic, and surgical procedures. In order to have successful dental outcomes and minimize posttreatment dental complications, relevant disease indicators are noted. This review is to raise awareness of the impact of oral diseases in patients with sickle cell disease and to emphasize the importance of full medical disclosure, radiographic interpretation, and a well-documented medical history, and a well-written consultation which can guide treatment planning and greatly improve the course of dental treatment.

镰状细胞病（SCD）在遗传学上被描述为一种常染色体血液病，由一种突变形式的血红蛋白引起。发病率、危象发生的频率、贫血程度和受累的器官系统各有不同。牙科保健专业人员和其他专家通常要求在进行复杂的牙周、牙髓和外科手术前进行全面的医疗咨询。为了获得成功的牙科治疗结果并尽量减少治疗后的牙科并发症，需要注意相关的疾病指标。本综述旨在提高镰状细胞病患者对口腔疾病影响的认识，并强调充分的医疗信息披露、影像学解释、良好的病史记录和良好的书面咨询的重要性，这些可以指导治疗计划，极大地改善牙科治疗过程。

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引用次数: 0

Why men don't talk about domestic violence 为什么男人不谈论家庭暴力？

IF 2.5 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Journal of the National Medical Association

Pub Date : 2024-12-01 DOI: 10.1016/j.jnma.2024.10.005

David E. Myles

A personal anecdote highlighting the myriad myths and misconceptions about why men don't often report domestic violence and the steps that society can take to ensure that everyone who has experienced such violence gets the resources and support they need.

通过一则个人轶事，强调了关于男性为何不经常报告家庭暴力的各种神话和误解，以及社会可以采取哪些措施来确保每一个遭受过家庭暴力的人都能获得所需的资源和支持。

引用次数: 0

The association between heart failure and systemic inflammatory response index: A cross‐sectional study 心力衰竭与全身炎症反应指数之间的关系：横断面研究

IF 2.5 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Journal of the National Medical Association

Pub Date : 2024-12-01 DOI: 10.1016/j.jnma.2024.10.007

Yu Zheng , Zixing Nie , Yifan Zhang , Zhihua Guo

Background

The systemic inflammatory response index (SIRI) is a recently developed composite index that assesses the entire extent of inflammation in the body, closely linked to heart failure (HF). This study aimed to evaluate the potential association between SIRI and HF.

Methods

The cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES) database from 2001 to 2018. SIRI is calculated based on the counts of monocytes, neutrophils, and lymphocytes. A weighted multiple-variable linear regression model examined the correlation between SIRI and HF. Using restrained cubic splines explored the nonlinear relationship between the two, and the robustness of the results was verified by subgroup analysis and interaction tests.

Results

Our study included 30,294 participants, 814 of whom were diagnosed with HF and 29,480 with non-HF. The multiple linear regression analysis showed that SIRI was positively correlated with HF (OR = 1.66; 95 % CI, 1.21, 2.29) and that there was no nonlinear relationship between the two. This relationship persisted in subgroup analyses.

Conclusions

The results indicate a linear positive correlation between SIRI and HF. Further extensive prospective studies are needed to validate these findings.

背景：全身炎症反应指数（SIRI）是最近开发的一种评估体内炎症整体程度的综合指数，与心力衰竭（HF）密切相关。本研究旨在评估 SIRI 与 HF 之间的潜在关联：这项横断面研究利用了美国国家健康与营养调查（NHANES）数据库中 2001 年至 2018 年的数据。SIRI根据单核细胞、中性粒细胞和淋巴细胞的计数计算得出。加权多变量线性回归模型检验了 SIRI 与高频之间的相关性。使用约束立方样条探索了两者之间的非线性关系，并通过亚组分析和交互检验验证了结果的稳健性：我们的研究纳入了 30294 名参与者，其中 814 人被诊断为高血压，29480 人被诊断为非高血压。多元线性回归分析表明，SIRI 与 HF 呈正相关（OR = 1.66；95 % CI，1.21, 2.29），两者之间不存在非线性关系。这种关系在亚组分析中依然存在：研究结果表明，SIRI 和 HF 之间存在线性正相关。结论：研究结果表明，SIRI与HF之间存在线性正相关关系，需要进一步开展广泛的前瞻性研究来验证这些发现。

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引用次数: 0

A review of the risks and relationships between oral health and chronic diseases 口腔健康与慢性疾病之间的风险和关系综述

IF 2.5 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Journal of the National Medical Association

Pub Date : 2024-12-01 DOI: 10.1016/j.jnma.2024.01.003

Gail Cherry-Peppers , Cheryl Fryer , Andrea D. Jackson , Debra Ford , Alison Glascoe , Dawn Smith , Jacquelyn Dunmore-Griffith , Morton Iris , Dexter Woods , Gillian Robinson-Warner , Alphonzo Davidson , Crystal McIntosh , Jezelle Sonnier , Lisa Slade , Goulda Downer , Shakeya Mundey , Jennifer Darden-Wilson , Nyree Dawson , Arielle Downes , Adel Rizkalla , Theresa Watkins-Bryant

Advances in medical science and in preventive dentistry have changed the context of oral health. The American population is living longer with numerous complex chronic diseases. This paper is to raise awareness about the impact of multiple chronic diseases and their associations with oral diseases. Comorbidities can worsen the course of dental treatment. Inflammation has been the connecting factor in the bidirectional pattern of oral and systemic diseases. High occurrences of chronic diseases generally occur in aging as well as disadvantaged populations. Serious infections, slow healing, prolonged bleeding, and hospitalizations can escalate in patients with uncontrolled chronic diseases. A multidisciplinary team-based approach to patient management can minimize complications and unexpected challenges.

医学科学和预防性牙科的进步改变了口腔健康的环境。美国人口寿命越来越长，并患有多种复杂的慢性疾病。本文旨在提高人们对多种慢性疾病的影响及其与口腔疾病的关联的认识。合并症会使牙科治疗过程恶化。炎症一直是口腔和全身疾病双向模式的连接因素。慢性疾病的高发病率通常发生在老龄化和弱势群体中。严重感染、愈合缓慢、出血时间延长以及住院治疗等问题都可能在慢性病患者身上加剧。以多学科团队为基础的患者管理方法可以最大限度地减少并发症和意外挑战。

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引用次数: 0

Identification of immune-related hub genes in chronic obstructive pulmonary disease 鉴定慢性阻塞性肺病中的免疫相关枢纽基因。

IF 2.5 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Journal of the National Medical Association

Pub Date : 2024-12-01 DOI: 10.1016/j.jnma.2024.10.008

Lingyu Zhang , Liwei Zuo

Objective

As a prevalent persistent respiratory disease, chronic obstructive pulmonary disease (COPD) is featured by airflow limitation and chronic inflammation. This study focused on the identification of immune-related hub genes in COPD.

Methods

We employed the GSE38974 dataset to analyze differentially expressed genes (DEGs) of COPD. Then, we obtained COPD immune-related DEGs (COPD-IMDEGs) based on the intersection of DEGs and immune-related genes. Subsequently, we carried out Gene ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses on COPD-IMDEGs. We established a protein-protein interaction network based on COPD-IMDEGs. The hub genes were determined by utilizing the Maximal Clique Centrality method. We utilized receiver operating characteristic (ROC) curves to analyze the clinical significance of hub genes in COPD. In addition, potential drugs targeting hub genes were predicted based on interactions between hub gene-corresponding proteins and drugs.

Results

A total of 45 COPD-IMDEGs were obtained through differential analysis. Enrichment analyses showed that COPD-IMDEGs were associated with cytokines, growth factors, and receptor ligands. Ten COPD-IMDEGs were identified as hub genes. As shown by ROC curves, these genes had potential value in identifying COPD patients. Drug prediction results showed that simvastatin and other drugs targeted hub genes.

Conclusion

This study analyzed the potential biological functions enriched by COPD-IMDEGs, identified ten genes as biological markers for diagnosing COPD, and predicted potential drugs for treating COPD.

目的：慢性阻塞性肺疾病（COPD）是一种常见的呼吸系统顽疾，以气流受限和慢性炎症为主要特征。本研究的重点是识别 COPD 中与免疫相关的枢纽基因：方法：我们利用 GSE38974 数据集分析 COPD 的差异表达基因（DEGs）。然后，根据 DEGs 与免疫相关基因的交集，得到 COPD 免疫相关 DEGs（COPD-IMDEGs）。随后，我们对 COPD-IMDEGs 进行了基因本体和京都基因组百科全书富集分析。我们建立了基于 COPD-IMDEGs 的蛋白-蛋白相互作用网络。利用最大剪辑中心性方法确定了中心基因。我们利用接收器操作特征曲线（ROC）分析了枢纽基因在 COPD 中的临床意义。此外，我们还根据中枢基因对应的蛋白质与药物之间的相互作用，预测了针对中枢基因的潜在药物：结果：通过差异分析共获得 45 个 COPD-IMDEGs 。富集分析表明，COPD-IMDEGs 与细胞因子、生长因子和受体配体有关。有 10 个 COPD-IMDEG 被确定为枢纽基因。如 ROC 曲线所示，这些基因具有识别 COPD 患者的潜在价值。药物预测结果表明，辛伐他汀和其他药物都以枢纽基因为靶点：本研究分析了COPD-IMDEGs富集的潜在生物功能，确定了10个基因作为诊断COPD的生物标记，并预测了治疗COPD的潜在药物。

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引用次数: 0

Statin use and its association with all-cause mortality and incident diabetes/prediabetes in African Americans: Findings from the jackson heart study 他汀类药物的使用及其与非裔美国人的全因死亡率和糖尿病/糖尿病发病率的关系：杰克逊心脏研究的结果。

IF 2.5 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Journal of the National Medical Association

Pub Date : 2024-12-01 DOI: 10.1016/j.jnma.2024.10.009

Alula Hadgu , Fengxia Yan , Valery Effoe , Robert Mayberry

Objectives

This study investigates the association between statin use and all-cause mortality, as well as the association between statin use and incident diabetes or prediabetes among African Americans.

Methods

This study is based on the Jackson Heart Study (JHS), a community-based cohort study of African Americans (AAs). The baseline period for JHS was 9/26/2000 to 3/31/2004. The first follow-up period was from 10/1/2005 to 12/21/2008, and the second follow-up period was from 2/26/2009 to 1/31/2013. All study participants who were statin users or non-users at baseline were included in this study. We applied two common propensity score adjustment techniques to analyze the data: propensity score matching (PSM) and the inverse probability of treatment weighting (IPTW) algorithms.

Results

In this cohort there were 510 deaths. The baseline prevalence of statin use was 13.95% (95% CI: 12.91% - 14.98%), while the baseline rate of all-cause mortality was 11.82% (95% CI: 10.87% - 12.82%). In crude analyses, statin users had an 80% higher risk of mortality compared to non-users, with an odds ratio (OR) of 1.80 (95% CI: 1.43 - 2.27). However, after adjusting for confounders using PSM and IPTW, the adjusted ORs for the association between statin use and mortality were 0.77 (95% CI: 0.53 - 1.12) and 0.80 (95% CI: 0.68 - 0.95), respectively. A post hoc power analysis suggested that the matched analysis was underpowered.

The incidence of diabetes/ prediabetes was 39.42% (95% CI: 37.39% - 41.45%), with 879 new cases observed. Statin users had a crude odds ratio (OR) of 2.02 (95% CI: 1.52 - 2.67) for developing diabetes/prediabetes compared to non-users. After adjusting for confounding using PSM) and IPTW, the adjusted ORs were 1.84 (95% CI: 1.21–2.81) and 1.82 (95% CI: 1.59–2.08), respectively.

Conclusion

Statin use was associated with a 20% decrease in all-cause mortality but an 80% increased risk of incident diabetes/prediabetes. Clinicians should consider the implications of these findings when prescribing statins to patients in this population.

研究目的本研究调查了他汀类药物的使用与全因死亡率之间的关系，以及他汀类药物的使用与非裔美国人中糖尿病或糖尿病前期事件之间的关系：本研究基于杰克逊心脏研究（Jackson Heart Study，JHS），这是一项针对非裔美国人（AAs）的社区队列研究。JHS 的基线期为 2000 年 9 月 26 日至 2004 年 3 月 31 日。第一次随访期为 2005 年 1 月 10 日至 2008 年 12 月 21 日，第二次随访期为 2009 年 2 月 26 日至 2013 年 1 月 31 日。所有基线时使用或未使用他汀类药物的研究参与者均被纳入本研究。我们采用了两种常见的倾向得分调整技术来分析数据：倾向得分匹配（PSM）和逆治疗概率加权（IPTW）算法：该队列中共有 510 人死亡。他汀类药物的基线使用率为 13.95%（95% CI：12.91% - 14.98%），而全因死亡率的基线为 11.82%（95% CI：10.87% - 12.82%）。在粗略分析中，他汀类药物使用者的死亡风险比非使用者高出 80%，几率比 (OR) 为 1.80（95% CI：1.43 - 2.27）。然而，在使用 PSM 和 IPTW 对混杂因素进行调整后，他汀类药物使用与死亡率之间的调整 OR 分别为 0.77（95% CI：0.53 - 1.12）和 0.80（95% CI：0.68 - 0.95）。事后功率分析表明，配对分析的功率不足。糖尿病/糖尿病前期的发病率为 39.42%（95% CI：37.39% - 41.45%），观察到 879 个新病例。与未使用他汀类药物者相比，使用他汀类药物者患糖尿病/糖尿病前期的粗略几率比 (OR) 为 2.02（95% CI：1.52 - 2.67）。使用 PSM 和 IPTW 对混杂因素进行调整后，调整后的 OR 分别为 1.84（95% CI：1.21-2.81）和 1.82（95% CI：1.59-2.08）：他汀类药物的使用与全因死亡率降低 20% 相关，但与糖尿病/糖尿并发症风险增加 80% 相关。临床医生在为这类人群的患者开具他汀类药物处方时，应考虑这些发现的影响。

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引用次数: 0