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Study of Optimized Simultaneous Extraction Conditions for Active Component of Ginseng Berry using Response Surface Methodology 响应面法优化人参莓有效成分同时提取条件的研究
Pub Date : 2020-01-01 DOI: 10.15230/SCSK.2020.46.2.185
Hee Kyoung Go, Junseong Park
This study was conducted to find out the optimal extraction conditions to obtain extracts with a high content of ginsenosides and antioxidant activity using the ginseng berry. After extraction by stirring, ultrasound and microwave method using 70% ethanol and distilled water as solvents, the results of considering the content of ginsenoside Re and Rb1, total polyphenol content, antioxidant activity, and whether it is an environmentally friendly manufacturing method, it was confirmed that the microwave method using distilled water is good method of extraction. The optimization of extraction conditions for microwave method were made by response surface methodology (RSM). Microwave power (50 ∼ 200 W, X1), solvent and ginseng berry ratio (5 ∼ 20 times, X2) and the extraction time (30 ∼ 120 s, X3) were used as independent variables. The model showed a good fit having a determination coefficient of the regression equation of 0.9 or more and a p-value less than 0.05. Estimated conditions for the maximized extraction of ginsenoside contents and total polyphenols were 200 w in microwave power, 20 times in solvent and ginseng berry ratio, and 90 s in extraction time. Predicted values at the optimum conditions were total polyphenols of 6.23 mg GAE/g, ginsenoside Re of 17.69 mg/g, and ginsenoside Rb1 of 16.01 mg/g. In the verification of the actual measurement the obtained values showed 6.33 mg GAE/g, 17.79 mg/g, and 15.59 mg/g, respectively, in good agreement with predicted values.
以人参果为原料,研究了提取人参皂苷含量高、抗氧化活性高的最佳工艺条件。经搅拌、超声和微波法提取后,以70%乙醇和蒸馏水为溶剂,综合考虑人参皂苷Re和Rb1的含量、总多酚含量、抗氧化活性,以及是否是一种环保的制造方法,证实微波法采用蒸馏水提取是较好的提取方法。利用响应面法(RSM)对微波法提取条件进行了优化。以微波功率(50 ~ 200 W, X1)、溶剂与人参果比(5 ~ 20倍,X2)和提取时间(30 ~ 120 s, X3)为自变量。模型拟合良好,回归方程的决定系数大于等于0.9,p值小于0.05。微波功率为200 w,溶剂和人参果比为20倍,提取时间为90 s时,人参皂苷含量和总多酚的提取效果最佳。在最佳条件下的预测值为总多酚6.23 mg GAE/g,人参皂苷Re 17.69 mg/g,人参皂苷Rb1 16.01 mg/g。在对实际测量值的验证中,得到的值分别为6.33 mg GAE/g、17.79 mg/g和15.59 mg/g,与预测值吻合较好。
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引用次数: 0
Comparative Study of the Biological Activity of Propolis Extracts with Various Countries of Origin as Cosmetic Materials 不同原产地化妆品原料蜂胶提取物生物活性的比较研究
Pub Date : 2020-01-01 DOI: 10.15230/SCSK.2020.46.2.159
E. Jung, J. Weon, H. Ji, Jiyoung You, S. Oh, Hayeon Kim, Yingji Xin, Eun Bin Kim, Kang-Hyuck Heo, Park, Deok-Hoon
: Propolis is a sticky resinous substance that is formed by the combination of honeybee secretions and resin of plants, which serves to protect from bacteria and viruses. This study aims to evaluate the efficacy of propolis extract from Korea (KPE), China (CPE), and Brazil (BPE) through antioxidant, antibacterial, whitening, and anti-inflammatory tests, and to examine their potential as cosmetic materials. KPE, CPE, and BPE showed significant antioxidant activities on flavonoid/polyphenol content and free radical scavenging activity. The antibacterial effect of propolis on skin flora was determined by measuring the minimal inhibitory concentration (MIC). KPE showed better antibacterial efficacy than CPE and BPE in C. acnes (KPE, CPE, and BPE: (62.5, 250, and 500) µ g/mL, respectively). Furthermore, KPE inhibited the melanin synthesis in human epidermal melanocytes and production of nitric oxide and PGE 2 induced by lipopolysaccharide (LPS) in mouse macrophages, which showed better than did CPE or BPE. Taken together, the propolis extracts can be applied to antioxidant, antibacterial, and anti-inflammatory ingredient for cosmetics, while KPE showed superior potential in antibacterial, anti-inflammatory, and whitening efficacies.
蜂胶是一种粘稠的树脂状物质,由蜜蜂的分泌物和植物的树脂结合而成,具有保护细菌和病毒的作用。本研究旨在通过对韩国(KPE)、中国(CPE)和巴西(BPE)蜂胶提取物的抗氧化、抗菌、美白和抗炎等试验来评价其功效,并探讨其作为化妆品原料的潜力。KPE、CPE和BPE对黄酮/多酚含量和自由基清除活性均有显著的抗氧化活性。通过测定蜂胶对皮肤菌群的最小抑菌浓度(MIC)来测定蜂胶对皮肤菌群的抑菌效果。KPE对痤疮菌的抑菌效果优于CPE和BPE (KPE、CPE和BPE分别为(62.5、250和500)µg/mL)。此外,KPE对人表皮黑色素细胞黑色素合成和小鼠巨噬细胞脂多糖(LPS)诱导的一氧化氮和pge2生成的抑制作用优于CPE和BPE。综上所述,蜂胶提取物可用于化妆品的抗氧化、抗菌和抗炎成分,而KPE在抗菌、抗炎和美白功效方面具有较好的潜力。
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引用次数: 2
Anti-inflammatory Effects of Haliotis discus-derived Antibacterial Peptide (AMP) Ab4-7 as a F unctional material f or Improving Inflammatory Skin D iseases 灰鱼源抗菌肽(AMP) Ab4-7作为改善炎性皮肤D病的功能材料的抗炎作用
Pub Date : 2020-01-01 DOI: 10.15230/SCSK.2020.46.2.147
S. Choi, Jung‐Kil Seo, Joon-ho Hwang, Ki-Young Lee, Lee In-Ah
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引用次数: 0
Growth of Cosmetic OEM·ODM Companies and Industrial Roles 化妆品OEM·ODM公司的增长和行业角色
Pub Date : 2020-01-01 DOI: 10.15230/SCSK.2020.46.2.167
B. Lim, Jae Hong Park, Yong Chan An, Min Joo Kim
In this study, we analyzed the growth factors and industrial role of cosmetics OEM⋅ODM enterprises that have played an important role in Korea’s growth as the fourth-largest cosmetics exporter in the world. Since the OEM industry was first introduced to Korea by Kolmar Korea in 1990, the industry has grown to account for 12.619 trillion won as of 2016 and 69.9% of sales of local products. Also, the industry not only supported brand enterprises to enter the global market but also directly supplied products to global enterprises, contributing to economic growth and rising national prestige. Growth factors in Korea’s cosmetics OEM⋅ODM industry can be found in the development of differentiated business models, such as continuous technology development, active response to the industrial environment, and settling a system with technology and creative ideas. For sustained growth and development of Korean cosmetics industry, OEM⋅ODM needs to be settled as Korea’s own industry and co-exist with brand enterprises in complementary relations.
在本研究中,我们分析了化妆品OEM·ODM企业的增长因素和产业作用,这些企业在韩国成为世界第四大化妆品出口国的增长中发挥了重要作用。自1990年由科尔玛韩国引进代工产业以来,以2016年为基准,代工产业的规模达到了12.619万亿韩元,占国内产品销售额的69.9%。此外,该行业不仅支持品牌企业进入全球市场,还直接向全球企业提供产品,为经济增长和国家声誉的提升做出了贡献。韩国化妆品OEM·ODM行业的成长因素体现在持续的技术开发、积极应对产业环境、以技术和创意建立体系等差异化商业模式的发展中。为了韩国化妆品产业的持续增长和发展,需要将OEM⋅ODM定位为韩国自己的产业,与品牌企业互补共存。
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引用次数: 1
Study on the Classification and Improvement of Dehydrated Skin under Warm Air Heating Condition 暖风加热条件下脱水皮肤的分类及改善研究
Pub Date : 2020-01-01 DOI: 10.15230/SCSK.2020.46.2.179
Oh Sun Kwon, H. Kang, Seungho Han, J. Yoon, W. H. Cho, Joo-young Oh, J. Lim, Young-Sook Song, Sun Gyoo Park
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引用次数: 0
New Approaches to Increase Skin Efficacy of Chaga Mushroom Extract using High V oltage P ulsed Electric F ields Technology 利用高压脉冲电场技术提高白桦茸提取物皮肤功效的新方法
Pub Date : 2020-01-01 DOI: 10.15230/SCSK.2020.46.3.231
M. Sung, J. Kang, Y. Jeong, B. Kim, Hang-Eui Cho, H. Cho
In this study in order to develop new approaches we investigated using high voltage pulsed electric fields (PEF) technology to reduce the risks, protect the phyto-constituents and improve skin biological activities. After preparing a Chaga mushroom (Inonotus obliquus) extracts pretreated with PEF, components measurement and skin efficacy evaluation were performed. As a result of the content measurement, the content of polysaccharide and polyphenol were higher in the order of extracts treated with 50 Hz and 25 Hz at 0.5 kV/cm, and the content of protein was the highest in extracts treated with 25 Hz at 0.5k V/cm. Similar to the results of the polyphenol measurements, extracts treated with 25 Hz and 50 Hz at 0.5 kV/cm showed leading DPPH scavenging ability. The cell protection effect against sodium dodecyl sulfate (SDS) and UVB was finest in extracts treated with 25 Hz at 0.5 kV/cm, which had the highest protein content. And the hyaluronic acid synthesis was leading in extracts treated with 50 Hz and 100 Hz at 0.5 kV/cm. Therefore, the active ingredient of the high-voltage PEF pre-treatment Chaga mushroom extract can be developed as a functional material with cell protection and moisturizing effect, and such green technology is expected to be used in various fields of cosmetics and material development.
在本研究中,我们探讨了利用高压脉冲电场(PEF)技术来降低风险、保护植物成分和提高皮肤生物活性的新方法。制备经PEF预处理的白桦茸提取物,进行成分测定和皮肤功效评价。含量测定结果表明,0.5 kV/cm、50 Hz和25 Hz处理下,多糖和多酚含量最高;0.5 kV/cm、25 Hz处理下,蛋白质含量最高。与多酚测定结果相似,25 Hz和50 Hz 0.5 kV/cm处理的提取物具有领先的DPPH清除能力。以25 Hz 0.5 kV/cm处理的提取物对十二烷基硫酸钠(SDS)和UVB的细胞保护作用最好,蛋白质含量最高。在0.5 kV/cm、50 Hz和100 Hz处理下,透明质酸的合成率最高。因此,高压PEF预处理白桦菇提取物的活性成分可开发为具有细胞保护和保湿作用的功能材料,这种绿色技术有望应用于化妆品和材料开发的各个领域。
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引用次数: 0
Non-invasive Skin Barrier Lipid Packing Analysis Using FT-IR and Study of Cosmetic Formulation for Damaged Barrier 非侵入性皮肤屏障脂质堆积分析及受损屏障化妆品配方研究
Pub Date : 2020-01-01 DOI: 10.15230/SCSK.2020.46.3.307
H. Kim, Sun-Young Kim, Seol-Hoon Lee
The barrier structure of the skin’s epidermis is a key structure to prevent the loss of water inside the body and the invasion of foreign substances, and is composed of keratinocytes and intercellular lipids. At this time, the intercellular lipids of the skin barrier has the strongest structure when packed in an orthorhombic structure. However, it is damaged by various external causes and changes to a hexagonal structure. This change in physical structure can be analyzed non-invasively by analyzing the signal of the CH2-CH2 scissoring band of lipids using FT-IR. In this study, SDS was treated on porcine skin to construct a skin barrier damage model, and the degree of change in packing structure was quantified by analyzing FT-IR signals. We then judged whether the barrier of the damage model was recovered according to the treatment of the cosmetic formulation. From these results, an indirect method of measuring the water evaporation of the skin barrier to date can be supplemented. In addition, physical changes in the structure of the skin barrier can be utilized in a direct and efficient manner to identify the function and verify the formulation of various materials.
皮肤表皮的屏障结构是防止体内水分流失和外来物质侵入的关键结构,由角质形成细胞和细胞间脂质组成。此时,皮肤屏障的细胞间脂质在呈正交结构时具有最强的结构。然而,它受到各种外部原因的破坏而改变为六边形结构。这种物理结构的变化可以通过使用FT-IR分析脂质CH2-CH2剪切带的信号来非侵入性地分析。本研究将SDS处理于猪皮肤,建立皮肤屏障损伤模型,并通过分析FT-IR信号量化包装结构的变化程度。然后根据化妆品配方的处理来判断损伤模型的屏障是否恢复。从这些结果中,可以补充一种间接测量皮肤屏障水分蒸发的方法。此外,可以直接有效地利用皮肤屏障结构的物理变化来识别各种材料的功能和验证配方。
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引用次数: 0
A Study on Factors Affecting the Effect of Blue Light Blocking in Sunscreen 影响防晒剂阻挡蓝光效果的因素研究
Pub Date : 2020-01-01 DOI: 10.15230/SCSK.2020.46.4.383
S. Park, B. Kwak, Mi Gi Lee, Bin Bum-Ho
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引用次数: 1
Lactobacillus plantarum APsulloc 331261 Fermented Products as Potential Skin Microbial Modulation Cosmetic Ingredients 植物乳杆菌胶囊331261发酵产品作为潜在的皮肤微生物调节化妆品成分
Pub Date : 2020-01-01 DOI: 10.15230/SCSK.2020.46.1.23
Hanbyul Kim, K. Myoung, Hyun Gee Lee, Eun-jeong Choi, Taehun Park, S. An
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引用次数: 0
Optimization of Quantification Method of Ergotioneine in Pleurotus eryngii var. ferulae and Its Anti-Oxidant Activity 阿魏侧耳麦角甲苷含量测定方法优化及其抗氧化活性研究
Pub Date : 2020-01-01 DOI: 10.15230/SCSK.2020.46.1.49
Park, Seunghee, 이정민, Seung Ho Lee
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引用次数: 0
期刊
Journal of the Society of Cosmetic Scientists of Korea
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