Pub Date : 2020-01-01DOI: 10.15230/SCSK.2020.46.2.195
G. Park, B. Moon, Lim Hye-Sun
{"title":"Effects of 14 Chung-bu Medicinal Materials Described in the Dongui Bogam on Inflammatory Cytokines Production in HaCaT Keratinocytes","authors":"G. Park, B. Moon, Lim Hye-Sun","doi":"10.15230/SCSK.2020.46.2.195","DOIUrl":"https://doi.org/10.15230/SCSK.2020.46.2.195","url":null,"abstract":"","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"10 1","pages":"195-204"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75148756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.15230/SCSK.2020.46.1.57
Sang-Hun Song, Byung Tack Lim, S. Son, N. Kang
{"title":"Prevention of Protein Loss Using A Shield Coating According to Moisture Behavior in Human Hair","authors":"Sang-Hun Song, Byung Tack Lim, S. Son, N. Kang","doi":"10.15230/SCSK.2020.46.1.57","DOIUrl":"https://doi.org/10.15230/SCSK.2020.46.1.57","url":null,"abstract":"","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"313 1","pages":"57-65"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75835747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.15230/SCSK.2020.46.3.273
Kyung-Ju Lee, Wookju Jang, You Ah Kim, Park Byoungjun, Hak-Hee Kang
Aloe vera (Aloe barbadensis Miller) has been used since ancient times to improve various skin diseases such as burns, wounds, and eczema. It has been reported that Aloe vera contains vitamin, enzyme, mineral, sugar, phenolic compound, fatty acid and amino acid. Aloe vera changes its color from green to red under the extreme thermal and arid climate to protect itself. These morphological changes induce variation of composition such as increasing of aloe-emodin content. Aloe-emodin is one of the major anthraquinone in aloe family plants. Since aloe-emodin contains a polyphenolic structure, this compound may be responsible for the reported antioxidant and anti-inflammatory effects of aloe. However, there is no research on the process of increasing the compounds of Aloe vera. Therefore, the purpose of this study is to develop a pink aloe manufacturing process that increases the aloe-emodin content and enhances the antioxidant and anti-inflammatory activities of aloe. As a result of heating aloe under appropriate conditions, pink aloe increased aloe-emodin content compared to general aloe, and exhibited effects such as increasing antioxidant activity, inhibiting NO production, and promoting cell regeneration. Through this study, the applicability of pink aloe as a new anti-aging material in the cosmetic field was confirmed.
{"title":"Antioxidant, Inhibitory on NO Production and In-vitro Cell Regeneration Effects of Pink-aloe","authors":"Kyung-Ju Lee, Wookju Jang, You Ah Kim, Park Byoungjun, Hak-Hee Kang","doi":"10.15230/SCSK.2020.46.3.273","DOIUrl":"https://doi.org/10.15230/SCSK.2020.46.3.273","url":null,"abstract":"Aloe vera (Aloe barbadensis Miller) has been used since ancient times to improve various skin diseases such as burns, wounds, and eczema. It has been reported that Aloe vera contains vitamin, enzyme, mineral, sugar, phenolic compound, fatty acid and amino acid. Aloe vera changes its color from green to red under the extreme thermal and arid climate to protect itself. These morphological changes induce variation of composition such as increasing of aloe-emodin content. Aloe-emodin is one of the major anthraquinone in aloe family plants. Since aloe-emodin contains a polyphenolic structure, this compound may be responsible for the reported antioxidant and anti-inflammatory effects of aloe. However, there is no research on the process of increasing the compounds of Aloe vera. Therefore, the purpose of this study is to develop a pink aloe manufacturing process that increases the aloe-emodin content and enhances the antioxidant and anti-inflammatory activities of aloe. As a result of heating aloe under appropriate conditions, pink aloe increased aloe-emodin content compared to general aloe, and exhibited effects such as increasing antioxidant activity, inhibiting NO production, and promoting cell regeneration. Through this study, the applicability of pink aloe as a new anti-aging material in the cosmetic field was confirmed.","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"46 1","pages":"273-282"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78232442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.15230/SCSK.2020.46.4.415
H. Cho, Ji-Wan Jeong, H. Ryu, Jung-No Lee, Sung-Min Park
{"title":"Dermal Papilla Cells Proliferation Constituent of Schisandra chinensis Fruits and Optimization Using Response Surface Methodology","authors":"H. Cho, Ji-Wan Jeong, H. Ryu, Jung-No Lee, Sung-Min Park","doi":"10.15230/SCSK.2020.46.4.415","DOIUrl":"https://doi.org/10.15230/SCSK.2020.46.4.415","url":null,"abstract":"","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"5 1","pages":"415-424"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74515344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.15230/SCSK.2020.46.1.43
B. Woo, S. Shin, Y. Hong, Y. Joo, Y. Jeong, Beom-Jin Lee, Soo-Dong Kim
{"title":"Adamantyl-based N-arylamide as a Novel Series of Androgen Receptor Antagonists","authors":"B. Woo, S. Shin, Y. Hong, Y. Joo, Y. Jeong, Beom-Jin Lee, Soo-Dong Kim","doi":"10.15230/SCSK.2020.46.1.43","DOIUrl":"https://doi.org/10.15230/SCSK.2020.46.1.43","url":null,"abstract":"","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"6 1","pages":"43-47"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85018005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.15230/SCSK.2020.46.4.391
Kyung‐Ha Lee, Wanil Kim
{"title":"Roles of Fisetin on Skin Barrier Function and Anti-aging in Epidermal Keratinocyte","authors":"Kyung‐Ha Lee, Wanil Kim","doi":"10.15230/SCSK.2020.46.4.391","DOIUrl":"https://doi.org/10.15230/SCSK.2020.46.4.391","url":null,"abstract":"","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"364 1","pages":"391-401"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75502445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.15230/SCSK.2020.46.3.207
S. Jo, Jung Eun Kim, N. Lee
In this study, the anti-inflammatory and anti-bacterial activities of the extracts from the leaves of the Hydrangea petiolaris were identified, and the chemical structure was identified by separating the active ingredient. As the result of the anti-inflammatory activity experiment using RAW 264.7 cells, it was confirmed that the n-hexane (Hex) and ethyl acetate (EtOAc) fractions inhibited the production of nitric oxide (NO) and the expression of iNOS protein in a concentration-dependent manner without cytotoxicity. In addition, the n-Hex and EtOAc fractions reduced the production of pro-inflammatory cytokines (TNF-α, IL-1β and IL-6). Upon the anti-bacterial tests using Staphylococcus epidermidis and Cutibacterium acnes, the extract, n-Hex, EtOAc and n-butanol (BuOH) fractions showed potent activities. In order to isolate the active constituents, the n-Hex and EtOAc fractions were further purified to afford four phytochemicals; phytol (1), corosolic acid (2), asiatic acid (3) and 1-O-p-coumaroyl-β-D-glucopyranoside (4). All of the compounds 1 – 4 were isolated for the first time from this plant. In addition, the contents of isolated compounds were determined by HPLC and the quantity of phytol (1) was 27.8 mg/g for the 70% EtOH extract. Based on the above research results, it is believed that it will be possible to develop a natural cosmetic material that has anti-inflammatory and anti-bacterial effects using the extract of H. petiolaris leaves.
本研究鉴定了小绣球叶提取物的抗炎和抗菌活性,并通过分离活性成分对其化学结构进行了鉴定。通过对RAW 264.7细胞的抗炎活性实验,证实了正己烷(Hex)和乙酸乙酯(EtOAc)组分抑制一氧化氮(NO)的产生和iNOS蛋白的表达呈浓度依赖性,无细胞毒性。此外,n-Hex和EtOAc组分减少了促炎细胞因子(TNF-α, IL-1β和IL-6)的产生。经表皮葡萄球菌和痤疮角质杆菌的抑菌试验,提取物、正己烯、乙酸乙酯和正丁醇(BuOH)组分显示出较强的抑菌活性。为了分离活性成分,进一步纯化了n-Hex和EtOAc组分,得到了4种植物化学物质;其中叶绿醇(1)、花冠果酸(2)、亚洲果酸(3)和1- o -对香豆醇-β- d -葡萄糖吡喃苷(4)。化合物1 ~ 4均为首次从该植物中分离得到。HPLC法测定分离化合物的含量,70% EtOH提取物中叶绿醇(1)含量为27.8 mg/g。基于以上研究结果,认为利用小叶红叶提取物开发具有抗炎抗菌作用的天然化妆品材料是可能的。
{"title":"Anti-inflammatory and Anti-bacterial Active Ingredients Derived from the Extract of the Leaves of Hydrangea Petiolaris","authors":"S. Jo, Jung Eun Kim, N. Lee","doi":"10.15230/SCSK.2020.46.3.207","DOIUrl":"https://doi.org/10.15230/SCSK.2020.46.3.207","url":null,"abstract":"In this study, the anti-inflammatory and anti-bacterial activities of the extracts from the leaves of the Hydrangea petiolaris were identified, and the chemical structure was identified by separating the active ingredient. As the result of the anti-inflammatory activity experiment using RAW 264.7 cells, it was confirmed that the n-hexane (Hex) and ethyl acetate (EtOAc) fractions inhibited the production of nitric oxide (NO) and the expression of iNOS protein in a concentration-dependent manner without cytotoxicity. In addition, the n-Hex and EtOAc fractions reduced the production of pro-inflammatory cytokines (TNF-α, IL-1β and IL-6). Upon the anti-bacterial tests using Staphylococcus epidermidis and Cutibacterium acnes, the extract, n-Hex, EtOAc and n-butanol (BuOH) fractions showed potent activities. In order to isolate the active constituents, the n-Hex and EtOAc fractions were further purified to afford four phytochemicals; phytol (1), corosolic acid (2), asiatic acid (3) and 1-O-p-coumaroyl-β-D-glucopyranoside (4). All of the compounds 1 – 4 were isolated for the first time from this plant. In addition, the contents of isolated compounds were determined by HPLC and the quantity of phytol (1) was 27.8 mg/g for the 70% EtOH extract. Based on the above research results, it is believed that it will be possible to develop a natural cosmetic material that has anti-inflammatory and anti-bacterial effects using the extract of H. petiolaris leaves.","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"54 1","pages":"207-218"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84457858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.15230/SCSK.2020.46.3.243
Ji-young Maeng, G. Nam
Using Fervidobacterium islandicum AW-1, polar low molecular weight keratin peptides were produced and confirmed through factors related to the skin elasticity. As a result of confirming the cytotoxicity and collagen synthesis ability according to the concentration of the polar low molecular weight keratin peptide in human fibroblasts, it was confirmed that the cytotoxicity did not appear and the collagen synthesis in human fibroblasts was increased. A mask pack containing a polar low-molecular weight keratin peptide was used, and a test product was used for 4 weeks in 22 healthy women subjects. As a result, it showed statistically significant effects on skin elasticity, skin torsion elasticity, skin color and moisture improvement. Through this test, it was confirmed that the polar low-molecular keratin peptide can be used as a cosmetic ingredient that helps improve skin elasticity.
{"title":"Study on Effect of Skin Elasticity by Polar Low Molecular Weight Keratin Peptide","authors":"Ji-young Maeng, G. Nam","doi":"10.15230/SCSK.2020.46.3.243","DOIUrl":"https://doi.org/10.15230/SCSK.2020.46.3.243","url":null,"abstract":"Using Fervidobacterium islandicum AW-1, polar low molecular weight keratin peptides were produced and confirmed through factors related to the skin elasticity. As a result of confirming the cytotoxicity and collagen synthesis ability according to the concentration of the polar low molecular weight keratin peptide in human fibroblasts, it was confirmed that the cytotoxicity did not appear and the collagen synthesis in human fibroblasts was increased. A mask pack containing a polar low-molecular weight keratin peptide was used, and a test product was used for 4 weeks in 22 healthy women subjects. As a result, it showed statistically significant effects on skin elasticity, skin torsion elasticity, skin color and moisture improvement. Through this test, it was confirmed that the polar low-molecular keratin peptide can be used as a cosmetic ingredient that helps improve skin elasticity.","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"41 1","pages":"243-252"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73831729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.15230/SCSK.2020.46.3.283
Eunhye Ko, S. Nam, Hana Jeong, Bo Yun Kim, Sang Hwa Kwak, S. Kim, In Ki Hong, Hak-Hee Kang
{"title":"Antioxidant, Anti-inflammatory and Anti-allergenic Effects of Citrus Junos seed Oil and its Human Skin Protection","authors":"Eunhye Ko, S. Nam, Hana Jeong, Bo Yun Kim, Sang Hwa Kwak, S. Kim, In Ki Hong, Hak-Hee Kang","doi":"10.15230/SCSK.2020.46.3.283","DOIUrl":"https://doi.org/10.15230/SCSK.2020.46.3.283","url":null,"abstract":"","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"80 1","pages":"283-294"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76806356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.15230/SCSK.2020.46.2.185
Hee Kyoung Go, Junseong Park
This study was conducted to find out the optimal extraction conditions to obtain extracts with a high content of ginsenosides and antioxidant activity using the ginseng berry. After extraction by stirring, ultrasound and microwave method using 70% ethanol and distilled water as solvents, the results of considering the content of ginsenoside Re and Rb1, total polyphenol content, antioxidant activity, and whether it is an environmentally friendly manufacturing method, it was confirmed that the microwave method using distilled water is good method of extraction. The optimization of extraction conditions for microwave method were made by response surface methodology (RSM). Microwave power (50 ∼ 200 W, X1), solvent and ginseng berry ratio (5 ∼ 20 times, X2) and the extraction time (30 ∼ 120 s, X3) were used as independent variables. The model showed a good fit having a determination coefficient of the regression equation of 0.9 or more and a p-value less than 0.05. Estimated conditions for the maximized extraction of ginsenoside contents and total polyphenols were 200 w in microwave power, 20 times in solvent and ginseng berry ratio, and 90 s in extraction time. Predicted values at the optimum conditions were total polyphenols of 6.23 mg GAE/g, ginsenoside Re of 17.69 mg/g, and ginsenoside Rb1 of 16.01 mg/g. In the verification of the actual measurement the obtained values showed 6.33 mg GAE/g, 17.79 mg/g, and 15.59 mg/g, respectively, in good agreement with predicted values.
{"title":"Study of Optimized Simultaneous Extraction Conditions for Active Component of Ginseng Berry using Response Surface Methodology","authors":"Hee Kyoung Go, Junseong Park","doi":"10.15230/SCSK.2020.46.2.185","DOIUrl":"https://doi.org/10.15230/SCSK.2020.46.2.185","url":null,"abstract":"This study was conducted to find out the optimal extraction conditions to obtain extracts with a high content of ginsenosides and antioxidant activity using the ginseng berry. After extraction by stirring, ultrasound and microwave method using 70% ethanol and distilled water as solvents, the results of considering the content of ginsenoside Re and Rb1, total polyphenol content, antioxidant activity, and whether it is an environmentally friendly manufacturing method, it was confirmed that the microwave method using distilled water is good method of extraction. The optimization of extraction conditions for microwave method were made by response surface methodology (RSM). Microwave power (50 ∼ 200 W, X1), solvent and ginseng berry ratio (5 ∼ 20 times, X2) and the extraction time (30 ∼ 120 s, X3) were used as independent variables. The model showed a good fit having a determination coefficient of the regression equation of 0.9 or more and a p-value less than 0.05. Estimated conditions for the maximized extraction of ginsenoside contents and total polyphenols were 200 w in microwave power, 20 times in solvent and ginseng berry ratio, and 90 s in extraction time. Predicted values at the optimum conditions were total polyphenols of 6.23 mg GAE/g, ginsenoside Re of 17.69 mg/g, and ginsenoside Rb1 of 16.01 mg/g. In the verification of the actual measurement the obtained values showed 6.33 mg GAE/g, 17.79 mg/g, and 15.59 mg/g, respectively, in good agreement with predicted values.","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"2005 1","pages":"185-194"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86906222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}