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油溶性ビタミンC(テトラヘキシルデカン酸アスコルビル)を用いた損傷毛髪の改善 使用油溶性维生素C(四己基癸酸甲酚)改善受损毛发
Pub Date : 2018-09-20 DOI: 10.5107/SCCJ.52.205
武士 三園, 俊介 山口, 悟 橋本
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引用次数: 0
Influence of Scalp Problems on Physical Properties of Hair and Their Prevention by Plant Extracts 头皮问题对头发物理性质的影响及植物提取物的预防
Pub Date : 2018-01-01 DOI: 10.5107/sccj.52.16
R. Ehama, Y. Shimada, J. Nakanishi, Motofumi Hagihara, T. Iwabuchi
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引用次数: 0
Development of Sunscreen Having Excellent Washability with Specific Inorganic UV Scattering Agents and Dispersants 专用无机紫外线散射剂和分散剂的耐洗性优良防晒霜的研制
Pub Date : 2018-01-01 DOI: 10.5107/sccj.52.24
I. Takahashi, Kazuhiro Nemura, I. Sasaki
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引用次数: 0
Evaluation and Control of Skin Appearance for the Development of Cosmetics 化妆品开发中皮肤外观的评价与控制
Pub Date : 2018-01-01 DOI: 10.5107/SCCJ.52.2
T. Igarashi
The appearance of skin is one of the critical research targets in cosmetology since cosmetics are key items for improving or controlling skin appearance. Therefore, a lot of studies on skin appearance have been carried out for the development of cosmetics. Such previous cosmetic studies are roughly subdivided into several approaches: psychology-based, optics-based, and image-based ones. An approach based on visual information processing is also important, especially when the mechanism of the appearance perception is investigated. In these approaches, the optics-based one has the advantage of identifying the skin optical properties (e.g. reflection, translucency, and spectral properties) that relate to the features of the targeted appearance. The image-based approach has the advantage of identifying visual cues that induce the features of the targeted appearance. Since such optical properties and visual cues are crucial information for designing formulations and ingredients of cosmetics, studies on the skin appearance based on optics and image have been frequently carried out. In this paper, to begin with, the above-mentioned approaches are overviewed. Then, more details regarding the optics-based and image-based approaches are argued. Finally, some of the previous studies on the development of cosmetic ingredients for controlling the skin appearance, which employed opticsand image-based approaches, are reviewed.
由于化妆品是改善或控制皮肤外观的关键产品,因此皮肤外观是美容学的重要研究对象之一。因此,为了化妆品的开发,人们对皮肤外观进行了大量的研究。这些先前的化妆品研究大致分为几种方法:基于心理学的,基于光学的和基于图像的。基于视觉信息处理的方法也很重要,特别是在研究外观感知的机制时。在这些方法中,基于光学的方法具有识别与目标外观特征相关的皮肤光学特性(例如反射,半透明和光谱特性)的优势。基于图像的方法具有识别诱导目标外观特征的视觉线索的优点。由于这些光学性质和视觉线索是设计化妆品配方和成分的重要信息,因此基于光学和图像的皮肤外观研究已经频繁开展。本文首先对上述方法进行概述。然后,对基于光学和基于图像的方法进行了详细讨论。最后,综述了国内外在控制皮肤外观的化妆品成分开发方面的一些研究进展,包括光学和基于图像的方法。
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引用次数: 1
The Rapid and Precise Detection of Candida albicans in Cosmetic Products Using Loop-Mediated Isothermal Amplification (LAMP) 环介导等温扩增(LAMP)快速、精确检测化妆品中白色念珠菌
Pub Date : 2018-01-01 DOI: 10.5107/sccj.52.8
Seiko Ota, Takako Niimura, Ryuta Azuma, Ruka Suzuki, K. Kameyama, M. Nakade
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引用次数: 0
Three-phase Emulsification: Emulsion Technology without Use of Conventional Surfactant 三相乳化:不使用常规表面活性剂的乳化技术
Pub Date : 2017-01-01 DOI: 10.5107/SCCJ.50.283
K. Tajima, Y. Imai
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引用次数: 1
The Involvement of Nitric Oxide in Skin Dullness Induced by Mechanical Stimulation 一氧化氮在机械刺激引起的皮肤迟钝中的作用
Pub Date : 2017-01-01 DOI: 10.5107/SCCJ.51.12
Maki Yusuke, Morita Miho, Asai Sakiko, Morita Satoshi
Dullness of the skin around the eyes is one of the most serious cosmetic problems. However, the causative mechanism of skin dullness, especially in the skin of the upper eyelids, remains unclear, and effective treatment needs to be established. The skin of the upper eyelids is particu-larly exposed to mechanical stimulation such as compression or friction by repetitive and multiple applications or removals of make-up. Mechanical stimulation has already been reported to induce hyperpigmentation of the skin. We hypothesized that dullness of the skin of the upper eyelids might be caused by melanin formation through mechanical stimulation. We conducted two ex-periments using reconstructed human skin models; the first experiment showed that repetitive loadings of weight resulted in the activation of melanogenesis, and the second one demonstrated that the activation of melanogenesis was inhibited by the addition of a nitric oxide scavenger. These results suggest that nitric oxide is involved in mechanical stimulation-induced melanogenesis. In addition, a skin lotion containing nitric oxide scavenging preparation, wasuregusa flower ferment filtrate, did not reduce the dullness of the skin of the cheeks, where the relative frequency of mechanical stimulation is low, but did reduce that of the upper eyelids. These results support our hypothesis that mechanical stimulation contributes to the dullness of the skin of the upper eyelids and suggest that nitric oxide plays an important role in mechanical stimulation-induced melanogenesis. Therefore, nitric oxide and its generation need to be targeted to reduce skin dullness.
眼周皮肤暗沉是最严重的美容问题之一。然而,皮肤暗沉,尤其是上眼睑皮肤暗沉的病因机制尚不清楚,需要建立有效的治疗方法。上眼睑的皮肤特别容易受到机械刺激,如反复多次涂抹或卸妆所造成的压迫或摩擦。据报道,机械刺激可诱发皮肤色素沉着。我们假设上眼睑皮肤暗沉可能是由机械刺激形成的黑色素引起的。我们使用重建的人体皮肤模型进行了两次实验;第一个实验表明,重复的体重负荷导致黑色素生成的激活,第二个实验表明,添加一氧化氮清除剂可以抑制黑色素生成的激活。这些结果表明一氧化氮参与了机械刺激诱导的黑色素生成。此外,一种含有一氧化氮清除制剂的皮肤洗液,wasuregusa花发酵滤液,并没有减少机械刺激频率相对较低的脸颊皮肤的暗沉,但确实减少了上眼睑的暗沉。这些结果支持了我们的假设,即机械刺激导致上眼睑皮肤暗沉,并表明一氧化氮在机械刺激诱导的黑色素生成中起重要作用。因此,一氧化氮及其生成需要有针对性地减少皮肤暗沉。
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引用次数: 1
Imaging of Photo-Damaged Hair with a Differential Phase Scanning X-Ray Microscopy 光损伤的头发成像与差相扫描x射线显微镜
Pub Date : 2017-01-01 DOI: 10.5107/sccj.51.230
T. Kawai, Takafumi Inoue, Takeshi Fujimori, K. Takehara, A. Takeuchi, K. Uesugi, Yoshio Suzuki
In recent years, hair damage by sunlight and chemical treatment such as perming and bleaching has become a consumer concern. It is important to understand the effect of sunlight and chemical treatment on hair microstructure to develop the technology for protection and repair of hair. Our previous study demonstrated that a differential phase contrast scanning X-ray microscopy was a useful nondestructive analysis method to observe internal hair structure with high-resolution. In this study, hair samples with three different chemical treatment ( normal, perming and bleaching ) and additional irradiation by artificial sunlight were observed with a scanning X-ray microscopic tomography system using a synchrotron radiation light source in order to understand the damag-ing effect of both sunlight and chemical treatment on hair. The porosity rate in the cortex is higher in the permed hair than normal hair and void distribution in the cross section of permed hair is localized. The porosity rate in the cortex of permed hair is decreased by additional irradiation. The porosity rate of bleached hair is the same as that of normal hair and isn ʼ t changed by the irradiation. These results suggest that hair microstructural change in the cortex by sunlight is affected by the prior chemical treatments, and development of varied protection and repair technology de-pending on the prior treatment situation is needed.
近年来,阳光和烫发、漂白等化学处理对头发的损害已成为消费者关注的问题。了解阳光和化学处理对头发微观结构的影响,对开发头发的保护和修复技术具有重要意义。我们之前的研究表明,差相衬扫描x射线显微镜是一种有效的高分辨率观察毛发内部结构的无损分析方法。在这项研究中,为了了解阳光和化学处理对头发的破坏作用,使用同步辐射光源的扫描x射线显微断层扫描系统观察了三种不同化学处理(正常、烫发和漂白)和人工阳光照射下的头发样本。烫发皮层孔隙率高于正常头发,且孔洞在头发横截面上的分布是局部的。烫发皮层的孔隙率因额外的照射而降低。漂白后的头发气孔率与正常头发气孔率相同,不受辐照的影响。这些结果表明,阳光照射下毛发皮层的微结构变化受到先前化学处理的影响,需要根据先前处理的情况开发不同的保护和修复技术。
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引用次数: 0
The Effect of Dipotassium Glycyrrhiza on Sensitive Skin Care 甘草二钾对敏感皮肤的护理作用
Pub Date : 2017-01-01 DOI: 10.5107/SCCJ.50.334
Keiko Yashiki, Nobuaki Ohto, Yoshihito Kawashima, Tatsuo Nakahara
Market volume of sensitive skin care products has continuously increased along with the increase in people’s concern about sensitive skin due to more stressful lifestyles and environmental degradation. We investigated whether dipotassium glycyrrhizate (DPG), the active ingredient which is most frequently utilized in sensitive skin care products in Japan, is able to reduce the expression of nerve growth factor (NGF), which upregulates hyperesthesia in the skin, a characteristic condition of sensitive skin, with an in vitro study. Furthermore, suppression effects in some parameters of sensory discomfort were found in a human stinging test using a formulation containing 5% lactic acid and with/without 0.2% DPG. In this study, DPG suggested the possibility of improvement for persons with various kinds of sensitive skin.
随着生活压力的增加和环境的恶化,人们对敏感皮肤的关注不断增加,敏感护肤品的市场数量也在不断增加。我们在体外研究了甘草酸二钾(DPG)是否能够降低神经生长因子(NGF)的表达,而神经生长因子(NGF)可以上调皮肤的过敏反应,这是敏感皮肤的一种特征状态。此外,在含有5%乳酸和含有/不含0.2% DPG的配方的人体蜇伤试验中,发现了对某些感官不适参数的抑制作用。在这项研究中,DPG为各种敏感皮肤的人提供了改善的可能性。
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引用次数: 1
Non-invasive Methods for Efficacy Test of Cosmetic Products by Examining the Skin Physiological Conditions 用皮肤生理条件检验化妆品功效的无创方法
Pub Date : 2017-01-01 DOI: 10.5107/SCCJ.51.105
Motoji Takahashi
Many bioengineering techniques to elucidate functions and characteristics of the skin have been developed. They measure such factors as the water content of the stratum corneum, transepidermal water loss ( TEWL ) , skin surface contour, mechanical properties, blood flow, sebum secre-tion rate, wrinkles, skin pigmentation, and so on. These instrumental measurements are applied to validation of the efficacy of the cosmetics. Recently, a few in vivo bio-microscopes which non-invasively visualize horizontal images or vertical cross sections of the skin with subcellular reso-lution, have been developed by using the non-linear optics phenomenon. In this paper, I review the skin measurement technologies that have been used for cosmetics efficacy test, and also describe in vivo bio-microscopes, which include optical coherence tomography ( OCT ), the confocal laser scanning microscope ( CLSM ) , the second harmonic generation ( SHG ) microscope, the multi photon microscope ( MPM ) , and coherent anti-Stokes Raman scattering ( CARS ), which will be very helpful to examine the effects of cosmetics on the skin.
许多阐明皮肤功能和特性的生物工程技术已经发展起来。他们测量诸如角质层含水量、经皮失水(TEWL)、皮肤表面轮廓、机械性能、血流、皮脂分泌率、皱纹、皮肤色素沉着等因素。这些仪器测量应用于化妆品功效的验证。近年来,利用非线性光学现象,已经开发出一些体内生物显微镜,这些显微镜可以以亚细胞分辨率无创地显示皮肤的水平图像或垂直横截面。本文综述了用于化妆品功效测试的皮肤测量技术,并介绍了体内生物显微镜,包括光学相干断层扫描(OCT)、共聚焦激光扫描显微镜(CLSM)、二次谐波产生显微镜(SHG)、多光子显微镜(MPM)和相干反斯托克斯拉曼散射(CARS),这将有助于研究化妆品对皮肤的影响。
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引用次数: 1
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Journal of the society of cosmetic chemists
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