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Diversity, Equity, and Inclusion Landscape of American Venous Forum 美国静脉论坛的多样性、公平性和包容性情况
IF 3.2 2区 医学 Q2 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101761
Lucy Yang , Ruth Bush , Kathleen Ozsvath , Karem Harth
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引用次数: 0
Concordance between preoperative imaging methods in patients with limb lymphedema undergoing supermicrosurgical lymphaticovenular anastomosis 接受超显微外科淋巴管-静脉吻合术的肢体淋巴水肿患者术前成像方法的一致性。
IF 2.8 2区 医学 Q2 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101891

Objective

Supermicrosurgical lymphaticovenular anastomosis (LVA) is increasingly being recognized as a first-line treatment of limb lymphedema because it is minimally invasive and highly effective. Lymphoscintigraphy and indocyanine green (ICG) lymphography are the two most commonly performed diagnostic imaging examinations to establish the indication and plan the procedure for patients affected by limb lymphedema. In a small group of patients, the information between these two imaging tools can be discordant, showing different anatomical drainage pathways or the absence of drainage and dermal backflow in one examination and valid drainage pathways in the other. The purpose of this study is to examine the types of possible discrepancies between lymphoscintigraphy of the superficial system and ICG lymphography and to describe the surgical outcomes after LVA for patients presenting with such discrepancies.

Methods

We retrospectively reviewed the data of all patients who underwent LVA for upper or lower limb lymphedema between July 2015 and July 2023. From this series, we identified a group of patients with nonconcordant imaging results from lymphoscintigraphy and ICG lymphography before lymphatic surgery. Nonconcordant findings were described in terms of “pattern discordance” and “pathway discordance.” The surgical outcome was measured by the change in the mean circumference of the limb after surgery. The changes between the preoperative and postoperative limb measures were analyzed using the Student t test. P values < .05 were considered significant.

Results

A total of 28 patients with limb lymphedema exhibited inconsistencies between preoperative lymphoscintigraphy of the superficial system and ICG lymphography. Among these patients, 14 experienced pattern discordance, 13 had pathway discordance, and 1 patient had both. After LVA, we observed a significant reduction in the average circumference of the affected limb in the analyzed group.

Conclusions

The discrepancy in the information between lymphoscintigraphy and ICG lymphography in the preoperative study of patients affected by limb lymphedema is rare but possible. This phenomenon is still not fully explained; however, our results suggest that it does not correlate with the outcome of supermicrosurgical LVAs.
目的上皮细胞手术淋巴管-静脉吻合术(LVA)因其微创、高效而被越来越多的人视为肢体淋巴水肿的一线治疗方法。淋巴管造影(Lymphoscintigraphy)和吲哚菁绿(ICG)淋巴造影(indocyanine green, ICG)是两种最常用的诊断成像检查方法,用于确定肢体淋巴水肿患者的适应症并制定手术计划。在一小部分患者中,这两种成像工具之间的信息可能不一致,在一种检查中显示不同的解剖引流路径,或没有引流和真皮回流,而在另一种检查中显示有效的引流路径。本研究的目的是检查浅表系统淋巴管造影和 ICG 淋巴造影之间可能存在差异的类型,并描述出现此类差异的患者在 LVA 后的手术结果。方法我们回顾性地审查了 2015 年 7 月至 2023 年 7 月期间因上肢或下肢淋巴水肿而接受 LVA 的所有患者的数据。从这一系列数据中,我们发现了一组淋巴手术前淋巴窥镜成像和ICG淋巴造影成像结果不一致的患者。不一致的结果用 "模式不一致 "和 "路径不一致 "来描述。手术结果以术后肢体平均周长的变化来衡量。术前和术后肢体测量值之间的变化采用学生 t 检验进行分析。结果共有28例肢体淋巴水肿患者的术前浅表系统淋巴管造影与ICG淋巴造影结果不一致。在这些患者中,14 例出现模式不一致,13 例出现路径不一致,1 例同时出现模式和路径不一致。结论 在对肢体淋巴水肿患者进行术前研究时,淋巴管造影和 ICG 淋巴造影的信息不一致的情况虽然罕见,但却有可能发生。然而,我们的研究结果表明,这种现象与超微创肢体淋巴水肿手术的结果无关。
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引用次数: 0
Decellularized Dermis Allograft for the Treatment of Chronic Venous Leg Ulceration – the DAVE Randomized Clinical Trial 用于治疗慢性静脉腿溃疡的脱细胞真皮异体移植--DAVE 随机临床试验
IF 3.2 2区 医学 Q2 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101753
Matthew Tan , Valeria Balan , Sarah Onida , Francine Heatley , Sarrah Peerbux , Robert Lee , John Norrie , Tristan Lane , David Epstein , Keith Poskitt , Nicky Cullum , Akila Chandrasekar , Richard Lomas , Alun Davies
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引用次数: 0
Shorter Time to Assessment and Anticoagulation with Decreased Mortality in Patients with Pulmonary Embolism Following Implementation of Artificial Intelligence Software 使用人工智能软件缩短肺栓塞患者的评估和抗凝时间并降低死亡率
IF 3.2 2区 医学 Q2 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101788
Jacob Shapiro , Saba Chowdhry , Adam Reichard , Patrick Muck , Matthew Recht , Aaron Kulwicki , Brian Kuhn , Mark Broering
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引用次数: 0
Do Sheath Length and ECMO Availability Correlate with Adverse Events in Patients Undergoing Percutaneous Thrombectomy for Pulmonary Embolism? 经皮血栓切除术治疗肺栓塞患者的鞘长和 ECMO 可用性与不良事件相关吗?
IF 3.2 2区 医学 Q2 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101789
Allie Olmstead
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引用次数: 0
A Meta-analysis of Thromboprophylaxis Measures During Travel and Guidance for Patients Who Travel After Varicose Vein Surgery 旅行期间血栓预防措施的 Meta 分析及静脉曲张手术后旅行患者指南
IF 3.2 2区 医学 Q2 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101794
Leona Takeuchi , Kanoklada Srikuea , Ehsanul Choudhury , Lily Benton , Stephen Black , Taha Khan
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引用次数: 0
Racial, Biological Sex, and Geographic Disparities of Pulmonary Embolism Prior to COVID-19 Era from a Nationwide Inpatient Sample (2016-2019) 从全国住院病人样本(2016-2019 年)看 COVID-19 时代之前肺栓塞的种族、生物性别和地域差异
IF 3.2 2区 医学 Q2 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101760
Ahmed Afifi, Matthew Leverich, Gang Ren, Mohamed Osman, Munier Nazzal
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引用次数: 0
VEIN STEP Mexico: A Prospective, Observational, International Study to Assess Effectiveness of Conservative Treatments in Chronic Venous Disease 墨西哥 VEIN STEP:一项评估慢性静脉疾病保守治疗效果的前瞻性、观察性国际研究
IF 3.2 2区 医学 Q2 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101811
Alejandro Gonzalez Ochoa
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引用次数: 0
Evidence for causal effects of neuropsychiatric conditions on risk of venous thromboembolism: A univariable and multivariable Mendelian randomization study 神经精神疾病对静脉血栓栓塞风险的因果效应证据:单变量和多变量孟德尔随机化研究。
IF 2.8 2区 医学 Q2 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101889

Background

Substantial observational evidence suggests an association between neuropsychiatric conditions and venous thromboembolism (VTE). However, the causal relationship between these two conditions requires further investigation. Therefore, we used a two-sample Mendelian randomization (MR) approach to assess the bidirectional causal effects between four neuropsychiatric conditions and VTE, deep vein thrombosis, and pulmonary embolism (PE).

Methods

Genetic variants associated with four neuropsychiatric conditions (ie, schizophrenia, major depressive disorder [MDD], bipolar disorder, and epilepsy) and VTE, deep vein thrombosis, and PE were selected. Bidirectional univariable and multivariable MR methods were applied to evaluate the causal relationships among these conditions. The primary causal estimates were obtained using the inverse variance weighted method with multiplicative random effects, supplemented by MR Egger regression, weighted median, simple mode, and weighted mode. Sensitivity analysis was conducted using the MR pleiotropy residual sum, funnel plots, and outlier (MR pleiotropy and residual sum and outlier) method.

Results

Univariable MR results showed that genetic susceptibility to MDD increases the risk of VTE and PE (VTE: odds ratio [OR], 1.25; 95% confidence interval [CI], 1.08-1.46; P = .004; PE: OR, 1.36; 95% CI, 1.09-1.69; P = .006) and that PE has an adverse causal effect on MDD (OR, 1.02; 95% CI, 1.00-1.04; P = .026). Adjustment for confounders such as obesity, sleep duration, smoking, physical activity, and alcohol consumption revealed that increased genetic susceptibility to MDD is also associated with VTE and PE.

Conclusions

Our results suggest that genetic susceptibility to MDD might have an adverse causal effect on the risk of VTE and PE and that PE has a reverse causal effect on MDD. Prevention and early diagnosis of depression are crucial in the management of VTE and PE.
背景大量观察证据表明,神经精神疾病与静脉血栓栓塞症(VTE)之间存在关联。然而,这两种情况之间的因果关系还需要进一步研究。因此,我们采用了双样本孟德尔随机化(MR)方法来评估四种神经精神疾病与 VTE、深静脉血栓和肺栓塞(PE)之间的双向因果效应。方法筛选出与四种神经精神疾病(即精神分裂症、重度抑郁障碍 [MDD]、双相情感障碍和癫痫)和 VTE、深静脉血栓和 PE 相关的遗传变异。采用双向单变量和多变量磁共振方法评估这些病症之间的因果关系。主要的因果关系估计值是采用具有乘法随机效应的反方差加权法,并辅以 MR Egger 回归、加权中位数、简单模式和加权模式得出的。使用 MR 多效应残差和、漏斗图和离群值(MR 多效应和残差和离群值)方法进行了敏感性分析。结果可变 MR 结果显示,MDD 遗传易感性会增加 VTE 和 PE 的风险(VTE:几率比 [OR],1.25;95% 置信区间 [CI],1.08-1.46;P = .004;PE:OR,1.36;95% CI,1.09-1.69;P = .006),PE 对 MDD 有不利的因果影响(OR,1.02;95% CI,1.00-1.04;P = .026)。对肥胖、睡眠时间、吸烟、体力活动和饮酒等混杂因素进行调整后发现,MDD 遗传易感性的增加也与 VTE 和 PE 相关。预防和早期诊断抑郁症对于治疗 VTE 和 PE 至关重要。
{"title":"Evidence for causal effects of neuropsychiatric conditions on risk of venous thromboembolism: A univariable and multivariable Mendelian randomization study","authors":"","doi":"10.1016/j.jvsv.2024.101889","DOIUrl":"10.1016/j.jvsv.2024.101889","url":null,"abstract":"<div><h3>Background</h3><div>Substantial observational evidence suggests an association between neuropsychiatric conditions and venous thromboembolism (VTE). However, the causal relationship between these two conditions requires further investigation. Therefore, we used a two-sample Mendelian randomization (MR) approach to assess the bidirectional causal effects between four neuropsychiatric conditions and VTE, deep vein thrombosis, and pulmonary embolism (PE).</div></div><div><h3>Methods</h3><div>Genetic variants associated with four neuropsychiatric conditions (ie, schizophrenia, major depressive disorder [MDD], bipolar disorder, and epilepsy) and VTE, deep vein thrombosis, and PE were selected. Bidirectional univariable and multivariable MR methods were applied to evaluate the causal relationships among these conditions. The primary causal estimates were obtained using the inverse variance weighted method with multiplicative random effects, supplemented by MR Egger regression, weighted median, simple mode, and weighted mode. Sensitivity analysis was conducted using the MR pleiotropy residual sum, funnel plots, and outlier (MR pleiotropy and residual sum and outlier) method.</div></div><div><h3>Results</h3><div>Univariable MR results showed that genetic susceptibility to MDD increases the risk of VTE and PE (VTE: odds ratio [OR], 1.25; 95% confidence interval [CI], 1.08-1.46; <em>P</em> = .004; PE: OR, 1.36; 95% CI, 1.09-1.69; <em>P</em> = .006) and that PE has an adverse causal effect on MDD (OR, 1.02; 95% CI, 1.00-1.04; <em>P</em> = .026). Adjustment for confounders such as obesity, sleep duration, smoking, physical activity, and alcohol consumption revealed that increased genetic susceptibility to MDD is also associated with VTE and PE.</div></div><div><h3>Conclusions</h3><div>Our results suggest that genetic susceptibility to MDD might have an adverse causal effect on the risk of VTE and PE and that PE has a reverse causal effect on MDD. Prevention and early diagnosis of depression are crucial in the management of VTE and PE.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"12 6","pages":"Article 101889"},"PeriodicalIF":2.8,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140761455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of Extremely Highly Exudative Venous Ulcers with 2-octyl-cyanoacrylate Adhesive. a Valid Alternative to End Exudation 用 2-辛基-氰基丙烯酸酯粘合剂治疗极度渗出性静脉溃疡。
IF 3.2 2区 医学 Q2 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101754
Jose Albino
{"title":"Treatment of Extremely Highly Exudative Venous Ulcers with 2-octyl-cyanoacrylate Adhesive. a Valid Alternative to End Exudation","authors":"Jose Albino","doi":"10.1016/j.jvsv.2024.101754","DOIUrl":"https://doi.org/10.1016/j.jvsv.2024.101754","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"12 3","pages":"Article 101754"},"PeriodicalIF":3.2,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213333X24000076/pdfft?md5=e89c1ae4f99846f20ab76aa578cad5f4&pid=1-s2.0-S2213333X24000076-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140553910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of vascular surgery. Venous and lymphatic disorders
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