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Journal of vascular surgery. Venous and lymphatic disorders最新文献

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Overlapping lockup lymphovenous anastomosis: Responding to comments by Depypere et al 重叠锁定淋巴管吻合术:回应 Depypere 等人的评论
IF 3.2 2区 医学 Q1 Medicine Pub Date : 2024-04-22 DOI: 10.1016/j.jvsv.2024.101847
Youmao Zheng BA , Liqi Yi BA , Cheng Wang BA , Shilin Gu BA , Chong Liu MD
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引用次数: 0
The value of the dermal rim sign on nonenhanced magnetic resonance imaging for predicting dermal backflow in patients with primary lower extremity lymphedema 非增强核磁共振成像上的真皮边缘标志对原发性下肢淋巴水肿患者真皮回流的预测价值。
IF 2.8 2区 医学 Q2 PERIPHERAL VASCULAR DISEASE Pub Date : 2024-04-16 DOI: 10.1016/j.jvsv.2024.101890

Purpose

The dermal rim sign (DRS) on nonenhanced magnetic resonance imaging has been shown to predict dermal backflow (DBF) in patients with secondary upper limb lymphedema. However, whether the DRS has the same effects on primary lower extremity lymphedema (PLEL) has not been clearly reported. Therefore, this study aimed to explore whether the DRS can be used to diagnose DBF on lymphoscintigraphy in patients with PLEL.

Methods

A total of 94 patients who were diagnosed with PLEL were recruited for this retrospective study from January 2022 to December 2023. All the patients were divided into two groups according to the lymphoscintigraphy findings: no DBF and DBF. The magnetic resonance imaging data of the two groups were recorded and statistically compared for the following indicators: range of lymphedema involvement (left, right, whole lower limbs, only thigh, only calf and ankle), signs of lymphedema (notable thickening of skin, parallel line sign, grid sign, honeycomb sign, band sign, lymph lake sign, crescent sign, DRS), and lymphedema measurement (skin thickness, band width). The DRS is characterized by notable thickening of the skin plus the grid sign and/or honeycomb sign, plus the band sign.

Results

The following statistically significant differences in the following indicators were found between the two groups (P < .05): notable skin thickening, parallel line sign, grid sign, honeycomb sign, band sign, DRS, skin thickness, and band width. The sensitivity, specificity, and accuracy for predicting for DBF with the DRS was 82%, 64%, and 77%, respectively.

Conclusions

This study confirmed good consistency between the DRS and DBF from the perspective of imaging. This tool is suitable for children, adolescents, and patients with contraindications to lymphoscintigraphy. The DRS has important value in assessing the severity of PLEL. The DRS is suggested for the clinical use of combined surgical treatment of PLEL.

目的 非增强磁共振成像上的真皮边缘征(DRS)已被证明可预测继发性上肢淋巴水肿患者的真皮回流(DBF)。然而,DRS是否对原发性下肢淋巴水肿(PLEL)具有同样的作用还没有明确的报道。因此,本研究旨在探讨 DRS 是否可用于诊断 PLEL 患者淋巴窥镜图上的 DBF。根据淋巴管造影结果将所有患者分为两组:无 DBF 组和 DBF 组。记录两组患者的磁共振成像数据,并对以下指标进行统计学比较:淋巴水肿累及范围(左、右、整个下肢、仅大腿、仅小腿和踝关节)、淋巴水肿体征(皮肤明显增厚、平行线征、网格征、蜂窝征、带征、淋巴湖征、新月征、DRS)和淋巴水肿测量(皮肤厚度、带宽)。DRS的特征是皮肤明显增厚,加上网格状标志和/或蜂窝状标志,再加上带状标志。结果发现两组患者在以下指标上差异有统计学意义(P <.05):皮肤明显增厚、平行线标志、网格状标志、蜂窝状标志、带状标志、DRS、皮肤厚度和带宽。使用 DRS 预测 DBF 的敏感性、特异性和准确性分别为 82%、64% 和 77%。该工具适用于儿童、青少年和有淋巴管造影禁忌症的患者。DRS 在评估 PLEL 的严重程度方面具有重要价值。建议将 DRS 用于 PLEL 的联合手术治疗。
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引用次数: 0
Longitudinal assessment of health-related quality of life and clinical outcomes with at home advanced pneumatic compression treatment of lower extremity lymphedema 在家高级气压疗法治疗下肢淋巴水肿的健康相关生活质量和临床疗效纵向评估。
IF 3.2 2区 医学 Q1 Medicine Pub Date : 2024-04-16 DOI: 10.1016/j.jvsv.2024.101892
Frank T. Padberg Jr. MD , Areck Ucuzian MD, PhD , Hasan Dosluoglu MD , Glenn Jacobowitz MD , Thomas F. O'Donnell MD

Objective

This prospective, longitudinal, pragmatic study describes at home treatment with a proprietary advanced pneumatic compression device (APCD) for patients with lower extremity lymphedema (LED).

Methods

Following institutiona review board approval, four participating Veterans Affairs centers enrolled LED patients from 2016 to 2022. The primary outcome measures were health-related quality of life (HR-QoL) questionnaires (lymphedema quality of life-leg and the generic SF-36v2) obtained at baseline and 12, 24, and 52 weeks. The secondary outcome measures were limb circumference, cellulitis events, skin quality, and compliance with APCD and other compression therapies.

Results

Because a portion of the trial was conducted during the coronavirus disease 2019 pandemic, 179 patients had 52 weeks of follow-up, and 143 had complete measurements at all time points. The baseline characteristics were a mean age of 66.9 ± 10.8 years, 91% were men, and the mean body mass index was 33.8 ± 6.9 kg/m2. LED was bilateral in 92.2% of the patients. Chronic venous insufficiency or phlebolymphedema was the most common etiology of LED (112 patients; 62.6%), followed by trauma or surgery (20 patients; 11.2%). Cancer treatment as a cause was low (4 patients; 2.3%). Patients were classified as having International Society for Lymphology (ISL) stage I (68.4%), II (27.6%), or III (4.1%). Of the primary outcome measures, significant improvements were observed in all lymphedema quality of life-leg domains of function, appearance, symptoms, and emotion and the overall score after 12 weeks of treatment (P < .0001) and through 52 weeks of follow-up. The SF-36v2 demonstrated significant improvement in three domains at 12 weeks and in the six domains of physical function, bodily pain, physical component (P < .0001), social functioning (P = .0181), role-physical (P < .0005), and mental health (P < .0334) at 52 weeks. An SF-36v2 score <40 indicates a substantial reduction in HR-QoL in LED patients compared with U.S. norms. Regarding the secondary outcome measures at 52 weeks, compared with baseline, the mean limb girth decreased by 1.4 cm (P < .0001). The maximal reduction in mean limb girth was 1.9 cm (6.0%) at 12 weeks in ISL stage II and III limbs. New episodes of cellulitis in patients with previous episodes (21.4% vs 6.1%, P = .001) were reduced. The 75% of patients with skin hyperpigmentation at baseline decreased to 40% (P < .01) at 52 weeks. At 52 weeks, compliance, defined as use for 5 to 7 days per week, was reported for the APCD by 72% and for elastic stockings by 74%.

Conclusions

This longitudinal study of Veterans Affairs patients with LED demonstrated improved generic and disease-specific HR-QoL through 52 weeks with at home use of an APCD. Limb girth, cellulitis episodes,

这项前瞻性、纵向、务实的研究介绍了使用专有的高级气动加压装置(APCD)对下肢淋巴水肿(LED)患者进行居家治疗的情况。方法在获得机构审查委员会的批准后,四个参与研究的退伍军人事务中心在 2016 年至 2022 年期间招募了 LED 患者。主要结局指标是在基线和 12、24 和 52 周进行的健康相关生活质量(HR-QoL)问卷调查(淋巴水肿生活质量-leg 和通用 SF-36v2)。次要结局指标为肢体周长、蜂窝织炎事件、皮肤质量以及对 APCD 和其他压力疗法的依从性。结果由于部分试验是在 2019 年冠状病毒疾病大流行期间进行的,因此有 179 名患者接受了 52 周的随访,其中 143 名患者在所有时间点都进行了完整的测量。基线特征为平均年龄(66.9 ± 10.8)岁,91%为男性,平均体重指数(33.8 ± 6.9 kg/m2)。92.2%的患者为双侧LED。慢性静脉功能不全或静脉性水肿是LED最常见的病因(112例患者,62.6%),其次是外伤或手术(20例患者,11.2%)。癌症治疗的病因较少(4 名患者;2.3%)。患者被分为国际淋巴学会(ISL)I期(68.4%)、II期(27.6%)或III期(4.1%)。在主要结果指标中,淋巴水肿患者在治疗 12 周后(P <.0001)和随访 52 周后,所有淋巴水肿生活质量--功能、外观、症状和情绪领域以及总分均有明显改善(P <.0001)。SF-36v2 在 12 周时显示三个领域有显著改善,在 52 周时显示身体功能、身体疼痛、身体组成部分(P <.0001)、社会功能(P = .0181)、角色-身体(P <.0005)和心理健康(P <.0334)六个领域有显著改善。与美国标准相比,SF-36v2 得分 40 表明 LED 患者的 HR-QoL 显著下降。关于 52 周时的次要结果测量,与基线相比,平均肢围减少了 1.4 厘米(P <.0001)。在12周时,ISL II期和III期患者肢体平均周长的最大降幅为1.9厘米(6.0%)。曾患蜂窝组织炎的患者新发蜂窝组织炎的比例(21.4% vs 6.1%,P = .001)有所降低。基线期75%的患者皮肤色素沉着率在52周时降至40%(P = .01)。52周时,72%的患者对APCD的依从性(定义为每周使用5至7天)和74%的患者对弹力袜的依从性(定义为每周使用5至7天)均有报告。结论这项针对退伍军人事务局LED患者的纵向研究表明,通过在家中使用APCD,52周后患者的一般和疾病特异性HR-QoL均有所改善。肢围、蜂窝组织炎发作次数和皮肤变色均有所减少,依从性极佳。
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引用次数: 0
Changes in Interface Pressure of Multilayer Compression After 1 Week 多层压缩 1 周后界面压力的变化
IF 3.2 2区 医学 Q1 Medicine Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101756
Antonios Gasparis, Ismene Germanakos, Nicos Labropoulos
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引用次数: 0
Clinical Factors Impacting Differences in Rates of Venous Thromboembolism Black and White Veterans 影响黑人和白人退伍军人静脉血栓栓塞率差异的临床因素
IF 3.2 2区 医学 Q1 Medicine Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101757
Hilary Hayssen , Shalini Sahoo , Brian Englum , Minerva Mayorga-Carlin , Tariq Siddiqui , Phuong Nguyen , Aman Kankaria , Yelena Yesha , John Sorkin , Brajesh Lal
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引用次数: 0
Usage of Virtual Reality Headsets During Office-Based Procedures to Lower Patient Anxiety and Pain 在诊室手术过程中使用虚拟现实耳机降低患者焦虑和疼痛感
IF 3.2 2区 医学 Q1 Medicine Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101804
Harsna Chahal, Judith Lin
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引用次数: 0
Efficacy and Security of Combined 1470 EVLA + Foam Sclerotherapy on the Management of C4 to C6 Patients 1470 EVLA + 泡沫硬化剂联合疗法治疗 C4 至 C6 患者的疗效和安全性
IF 3.2 2区 医学 Q1 Medicine Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101806
Erasto Aldrett, Nora Enid Lecuona
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引用次数: 0
In Vivo Evaluation of Safety and Performance of a Novel Microbubble-enhanced Ultrasound Pharmaco-mechanical Procedure in an Acute Porcine DVT Model 在急性猪深静脉血栓模型中对新型微泡增强超声药理机械程序的安全性和性能进行体内评估
IF 3.2 2区 医学 Q1 Medicine Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101796
William Marston , Craig Nichols , John Ranshaw , Jacob Ruprecht , Daniel Estay
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引用次数: 0
Risk Factors for Depression in Patients with Venous Stasis Ulcers 静脉瘀血溃疡患者抑郁的风险因素
IF 3.2 2区 医学 Q1 Medicine Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101755
Christopher Papatheofanis , Gennady Vulakh , Nadia Manzoor , Natalie Marks , Enrico Ascher , Anil Hingorani
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引用次数: 0
Monocentric Prospective Study to Valid Mutidisciplinary Diagnostic and Therapeutic Approach for Nutcracker Syndrome 单中心前瞻性研究,验证胡桃夹子综合征的多学科诊断和治疗方法
IF 3.2 2区 医学 Q1 Medicine Pub Date : 2024-04-15 DOI: 10.1016/j.jvsv.2024.101783
Gwenaël John
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引用次数: 0
期刊
Journal of vascular surgery. Venous and lymphatic disorders
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