Journal of vascular surgery. Venous and lymphatic disorders最新文献

{"title":"Optimizing Outcomes of the VenoValve in Patients With Chronic Venous Disease and Deep Venous Reflux: Two Years of Follow-up","authors":"Mikayla Lowenkamp MD , Cassius Iyad Ochoa Chaar MD, MPH, MS , Matthew Smeds MD , Marc Glickman MD , Eric Hager MD","doi":"10.1016/j.jvsv.2025.102413","DOIUrl":"10.1016/j.jvsv.2025.102413","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 2","pages":"Article 102413"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147396078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Trousseau to artificial intelligence: The future of occult cancer detection in unprovoked venous thromboembolism","authors":"Ioannis Tsouknidas MD , Arjun Jayaraj MD, FACS","doi":"10.1016/j.jvsv.2026.102443","DOIUrl":"10.1016/j.jvsv.2026.102443","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 2","pages":"Article 102443"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147325730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genome-wide association studies in chronic venous disease: A systematic review","authors":"Chien Lin Soh MBBChir, MA(Cantab), MRCS,&nbsp;Matthew Tan MBBS, BSc(Hons), PhD, MRCS, FHEA,&nbsp;Alun H. Davies DM, FRCS, MA, DSc, FHEA, FEBVS, FACPH, BM, BCh,&nbsp;Sarah Onida BSc(Hons), MD, PhD, FRCS","doi":"10.1016/j.jvsv.2025.102365","DOIUrl":"10.1016/j.jvsv.2025.102365","url":null,"abstract":"<div><h3>Background</h3><div>Chronic venous disease (CVD) arises from venous hypertension secondary to impaired venous return, causing significant morbidity and diminished quality of life. Genetic factors are likely important in the pathogenesis and susceptibility of a patient to develop CVD. This systematic review summarizes genome-wide association studies (GWASs) that investigate the link between genetic variants and CVD.</div></div><div><h3>Methods</h3><div>A systematic review was conducted in accordance with the PRISMA guidelines, with the search dates ranging from January 1, 1994, to July 17, 2025. Abstract and full-text screening were completed by two independent reviewers, with any conflicts referred to a third senior reviewer. GWASs in adults investigating links between genetic variants and CVD were included. Exclusion criteria included patients with venous thromboembolism, arterial or diabetic disease, or animal models.</div></div><div><h3>Results</h3><div>Thirteen studies were included after screening 517 studies from a search of PubMed, EMBASE, and Ovid. Database sources included UK Biobank, FinnGen, PopGen, and country- or hospital-specific databases with a majority Caucasian and European patient cohort. A total of 602,760 patients were identified with varicose veins and 3,664,604 control cases that were studied with GWASs and other statistical methods including a two-sample Mendelian randomization approach, functional mapping, and genetic correlations. A variety of statistically significant genetic polymorphisms were identified that can be attributed to the heritability of varicose veins affecting inflammation and immunity (eg, PPP3R1, EBF1, and GATA2), hypertension (eg, CASZ1), and vascular architecture (eg, CASZ1, PIEZO1, and STIM2). Protective variants (eg, GJD3, MMP10, and 4EBP1) were also identified in Finnish populations. However, replication studies showed that these genetic polymorphisms are not generalizable to specific populations.</div></div><div><h3>Conclusions</h3><div>This systematic review highlights genes contributing to the development of CVD that have been identified in the literature. An improved understanding of genetic contributions to the pathogenesis of CVD may inform future diagnostics, prognostics, and personalized treatment. Further larger scale studies representative of global populations, including meta-analyses of genome-wide association datasets, are required owing to individual GWASs being statistically insufficient to draw generalizable conclusions.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 2","pages":"Article 102365"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145757052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and Efficacy of Advanced Flush Endovenous Laser Ablation in Reducing Groin Recurrences: One-year Follow-up","authors":"Roman Lunin Dr,&nbsp;Uldis Maurins Professor,&nbsp;Andrejs Vanags Dr med,&nbsp;Marija Petrovica Surgeon,&nbsp;Alise Didrihsone Surgeon","doi":"10.1016/j.jvsv.2025.102400","DOIUrl":"10.1016/j.jvsv.2025.102400","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 2","pages":"Article 102400"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Junctional Reflux Impact the Effectiveness of Endovenous Ablation in Patients With Isolated Insufficiency of the Great Saphenous Vein","authors":"Chandu Vemuri MD, MBA ,&nbsp;Kathleen Gibson MD ,&nbsp;Mikel Sadek MD ,&nbsp;Cassius Ochoa-Chaar MD ,&nbsp;Antonios Gasparis MD ,&nbsp;Andrea Obi MD ,&nbsp;Windsor Ting MD ,&nbsp;Nicolas Mouawad MD ,&nbsp;Yana Etkin MD ,&nbsp;Shreef Said MD ,&nbsp;Anuj Mahajan MD ,&nbsp;Bjarnason Haraldur MD ,&nbsp;Shalini Sahoo PhD ,&nbsp;John Sorkin MD, PhD ,&nbsp;Brajesh Lal MD","doi":"10.1016/j.jvsv.2025.102395","DOIUrl":"10.1016/j.jvsv.2025.102395","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 2","pages":"Article 102395"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developmental Insights Into Left Common Iliac Vein Compression: A Comparative Cadaveric Study in Fetuses and Adult","authors":"Miguel Amore MD","doi":"10.1016/j.jvsv.2025.102393","DOIUrl":"10.1016/j.jvsv.2025.102393","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 2","pages":"Article 102393"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Thermal and Nonthermal Ablation for the Treatment of Venous Leg Ulcers","authors":"Nicholas Wells MA ,&nbsp;Jennifer Ellis MD ,&nbsp;Nicholas Osborne MD ,&nbsp;Alisha Oropallo MD ,&nbsp;Neil Khilnani MD ,&nbsp;Thomas O'Donnell MD ,&nbsp;Peter Lawrence MD ,&nbsp;Cassius Iyad Ochoa Chaar MD, MPH, MS","doi":"10.1016/j.jvsv.2025.102389","DOIUrl":"10.1016/j.jvsv.2025.102389","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 2","pages":"Article 102389"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Debulking Inflow and Outflow Obstructions: Multicenter Analysis With Mechanical Thrombectomy Toolkit","authors":"Steven Abramowitz MD ,&nbsp;Raja Ramaswamy DO ,&nbsp;Ryan O’Kelley DO ,&nbsp;Angelo Marino DO","doi":"10.1016/j.jvsv.2025.102392","DOIUrl":"10.1016/j.jvsv.2025.102392","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 2","pages":"Article 102392"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147396055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social Vulnerability Influences Primary Venous Leg Ulcer Healing and Recurrence","authors":"Joseph Hart MD, MHL ,&nbsp;Mona Li MD ,&nbsp;Mark Davies MD, PhD, MBA","doi":"10.1016/j.jvsv.2025.102426","DOIUrl":"10.1016/j.jvsv.2025.102426","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 2","pages":"Article 102426"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147396147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Signaling Pathway Predictors of Fibrosis From a Transcriptomic Analysis of Murine Venous Thrombosis","authors":"Benedict Turner MBChB, BSc, FHEA, MRCS ,&nbsp;Alun Davies DM, FRCS, MA, DSc, FHEA, FEBVS, FACPH, BM BCh ,&nbsp;Henry Bergman MBChB, BSc, MSc ,&nbsp;Alberto Smith PhD","doi":"10.1016/j.jvsv.2025.102425","DOIUrl":"10.1016/j.jvsv.2025.102425","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 2","pages":"Article 102425"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147394913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}