Journal of vascular surgery. Venous and lymphatic disorders最新文献

{"title":"Long-term efficacy of inguinal reoperation for recurrent saphenofemoral incompetence","authors":"Elitsa Valentinova Doncheva ,&nbsp;Stefania Aglaia Gerontopoulou MD ,&nbsp;Candan Altindas-Jürgensen ,&nbsp;Houman Jalaie MD ,&nbsp;Knuth Rass MD","doi":"10.1016/j.jvsv.2025.102353","DOIUrl":"10.1016/j.jvsv.2025.102353","url":null,"abstract":"<div><h3>Objective</h3><div>Recurrence originating from the saphenofemoral junction (SFJ) after an open surgical approach to or endovenous ablation of the great saphenous vein frequently occurs. The optimal treatment for a saphenofemoral recurrence remains a subject of debate. Currently, open redo surgery is becoming less common. This study analyzes the long-term effectiveness of saphenofemoral redo surgery following the principles of a modern surgical approach.</div></div><div><h3>Methods</h3><div>Patients who underwent saphenofemoral reoperation in 2015 and 2016 were identified retrospectively and invited to participate in a prospective follow-up examination. Redo surgery was performed under general and additional tumescent local anesthesia as inpatient treatment and included flush religation of the SFJ , stump suture, cauterization of the free endothelium, and removal of neovascularization. The following objectives were analyzed: Duplex ultrasound-detectable recurrent reflux at the SFJ, clinical recurrence according to Recurrent Varices After Surgery classification, disease severity and quality of life using standardized protocols (Revised Venous Clinical Severity Score, Homburg Varicose Vein Severity Score, Chronic Venous Insufficiency Questionnaire), and patient-reported satisfaction.</div></div><div><h3>Results</h3><div>A total of 84 patients (94 treated legs) were included with a median follow-up of 6.6 years. Five of the 94 legs (5.3%) had a duplex-detected reflux in the groin, with only 1 leg (1.1%) showing grade 2 neovascularization (vessel diameter of ≥4 mm). According to Recurrent Varices After Surgery classification, 2 of the 94 legs (2.1%) revealed clinical recurrence arising from the inguinal region. Disease severity at follow-up was low with a mean Revised Venous Clinical Severity Score_(0-30) of 1.8 ± 1.8 and a mean Homburg Varicose Vein Severity Score _(0-33) of 3.9 ± 3.4. According to the Clinical, Etiological, Anatomical and Pathological classification, the stage of disease improved significantly (<em>P</em> &lt; .001) in 55% of the treated legs. The procedure was well-accepted by patients: 94.1% indicated they would undergo saphenofemoral reoperation again if medically advised.</div></div><div><h3>Conclusions</h3><div>This study demonstrates that saphenofemoral redo surgery is very effective when certain technical strategies are implemented to prevent neovascularization. Long-term treatment results may be superior to minimally invasive procedures, indicating the need for comparative studies. Until such studies are available, open redo surgery should continue to be considered as an appropriate treatment option for saphenofemoral recurrence.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 1","pages":"Article 102353"},"PeriodicalIF":2.8,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145523452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with postoperative care among patients with varicose veins of the lower extremities","authors":"Jing Li MSN (RN) ,&nbsp;Edmund Xie BS ,&nbsp;Xiaojin Huang MD ,&nbsp;Xi Huang MSN candidate, RN ,&nbsp;Danyang Yu PhD ,&nbsp;In Hye Park PhD (RN) ,&nbsp;Yang Liu RN, PhD ,&nbsp;Peijia Zha PhD","doi":"10.1016/j.jvsv.2025.102354","DOIUrl":"10.1016/j.jvsv.2025.102354","url":null,"abstract":"<div><h3>Objective</h3><div>Varicose veins of the lower extremities are a prevalent chronic vascular condition. Effective postoperative self-management is crucial for recovery and preventing complications. However, there is limited understanding of the factors influencing patients’ self-management following surgical intervention. The objectives of this study were to investigate level of postoperative self-management ability and identify sociodemographic, clinical procedural, and health education factors that impact on postoperative self-management among patients with varicose veins of the lower extremities.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted using convenience sampling. A total of 622 patients from the Department of Vascular Surgery at a tertiary hospital in Xiamen completed the telephone survey between January 2022 and December 2022. Data were collected via a structured questionnaire, including sociodemographic, clinical procedural, health education, and self-management scales. Statistical analyses included univariate and bivariate analyses to identify key influencing factors.</div></div><div><h3>Results</h3><div>The overall score of postoperative self-management ability of patients with varicose veins of the lower extremities was moderately high (mean, 24.27). Sociodemographic, clinical procedural, and health education factors significantly impacted patient postoperative self-management. Sociodemographic characteristics, including gender, age, education level, living arrangement, and monthly income significantly impacted the postoperative self-management. Clinical manifestations-etiology-anatomy-pathophysiology (CEAP) classification, types of surgery, and postoperative time also significantly affected the postoperative self-management. Health education received after surgery and health education methods impacted the postoperative self-management ability of patients with varicose veins in the lower extremities.</div></div><div><h3>Conclusions</h3><div>Postoperative self-management was moderately high among patients with varicose veins of the lower extremities, but gaps in knowledge about complications and adherence to recommended practices were noted. Targeted, evidence-based health education tailored to individual patient characteristics can significantly improve self-management outcomes. This study underscores the importance of personalized interventions in enhancing patient-centered care and optimizing long-term recovery outcomes.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 1","pages":"Article 102354"},"PeriodicalIF":2.8,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145505237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of bleomycin polidocanol foam versus absolute ethanol for sclerotherapy of venous malformations","authors":"Jiayi Lai MD,&nbsp;Zian Xu MD,&nbsp;Hui Chen MD, PhD,&nbsp;Li Hu MD, PhD,&nbsp;Xiaoxi Lin MD, PhD,&nbsp;Xi Yang MD","doi":"10.1016/j.jvsv.2025.102352","DOIUrl":"10.1016/j.jvsv.2025.102352","url":null,"abstract":"<div><h3>Objective</h3><div>The purpose of this study was to compare the efficacy and safety between two sclerosants for venous malformations (VMs), bleomycin polidocanol foam (BPF) and absolute ethanol (AE), and provide more clinical evidence for the application of BPF for VMs.</div></div><div><h3>Methods</h3><div>We conducted a retrospective study of 104 patients with VMs who had been treated with BPF and AE sclerotherapy. Patients were followed-up after treatment to assess clinical efficacy and complications. Clinical efficacy was independently evaluated by three experts based on pre- and post-treatment photos and magnetic resonance images. Complications were categorized according to the Society of Interventional Radiology Adverse Event Classification System.</div></div><div><h3>Results</h3><div>A total of 104 patients with VM were enrolled in this study, of which 53 (51%) received BPF sclerotherapy, and 51 (49%) received AE sclerotherapy. Most of the patients had head and neck VMs (n = 64; 62%), and the most common symptom was disfigurement. The number of sessions in the BPF group was significantly lower than in the AE group (1.5 vs 2.2; <em>P</em> &lt; .05). The median treatment efficacy score was 3.0 for the BPF group and 2.7 for the AE group, with no significant difference between two groups. The median follow-up was 45 months for the BPF group and 33 months for the AE group, with no significant difference between two groups. Complications occurred in 11 patients in the BPF group and in 15 patients in the AE group, but there was no significant difference between the two groups. Mild adverse events occurred in 10 of 53 patients (19%) in the BPF group and 10 of 51 (20%) in the AE group. Moderate adverse events occurred in one patient (2%) in the BPF group and three patients (6%) in the AE group. Two patients (4%) in the AE group had nerve injury, evaluated as severe adverse events, whereas no patients in the BPF group did.</div></div><div><h3>Conclusions</h3><div>BPF has comparable treatment efficacy to AE in sclerotherapy for VMs. BPF showed a trend toward a lower rate of severe adverse events, although this difference was not statistically significant in our cohort. It could be an optimal sclerosant to treat VMs.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 2","pages":"Article 102352"},"PeriodicalIF":2.8,"publicationDate":"2025-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145476913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left renal vein thrombosis with nutcracker syndrome.","authors":"Xin Wei Zhou, Dong Zhe Chai, Hua Yi Zhang","doi":"10.1016/j.jvsv.2025.102288","DOIUrl":"10.1016/j.jvsv.2025.102288","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102288"},"PeriodicalIF":2.8,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12356302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcomes of venous tumor thrombectomy in renal cell carcinoma.","authors":"Sang Ah Lee, Hyeyeon Jang, Youngjin Han, Yong-Pil Cho, Jun Gyo Gwon","doi":"10.1016/j.jvsv.2025.102290","DOIUrl":"10.1016/j.jvsv.2025.102290","url":null,"abstract":"<p><strong>Objective: </strong>Renal cell carcinoma (RCC) has a unique feature in which tumor thrombus extends through the vein into the inferior vena cava. RCC with venous tumor thrombus is classified based on the level of thrombus. Standard treatment involves a combination of radical nephrectomy and tumor thrombectomy, despite the technical challenges associated with this approach. We aimed to evaluate the clinical outcomes based on the tumor thrombus level.</p><p><strong>Methods: </strong>We conducted a retrospective analysis of patients who underwent tumor resection and thrombectomy for RCC with venous tumor thrombus at a single center between January 2001 and December 2022. Tumor thrombus levels were classified into four levels (I-IV) according to the Mayo Clinic grading system, and patients were grouped based on the hepatic vein level: levels 0, I, and II were categorized as group 1, while levels III and IV were categorized as group 2. Survival outcomes were compared between the two groups using Kaplan-Meier survival analysis.</p><p><strong>Results: </strong>A total of 287 patients with RCC with venous tumor thrombus who underwent tumor resection and thrombectomy were identified. The distribution of patients according to the tumor thrombus level was as follows: 84 patients had level 0 thrombus, 71 had level I, 85 had level II, 19 had level III, and 28 had level IV. This results in 240 patients in group 1 (levels 0, I, and II) and 47 patients in group 2 (levels III and IV). The 5-year survival rates were 46.7% for group 1 and 53.2% for group 2. Kaplan-Meier survival analysis showed no significant difference in 5-year overall survival between the two groups (P = .75). However, patients in group 2 had a significantly longer postoperative hospital stay (21.43 ± 23.09 days) compared with those in group 1 (10.63 ± 6.31 days; P = .004).</p><p><strong>Conclusions: </strong>Tumor thrombus level is not a significant prognostic factor in RCC. Aggressive surgical removal should be considered, even for thrombus extending beyond the hepatic vein, given the acceptable prognosis.</p>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102290"},"PeriodicalIF":2.8,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12356288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidisciplinary management of intravenous leiomyomatosis with intracardiac extension","authors":"Chengyi Hui MD ,&nbsp;Min Qiu MD ,&nbsp;Jiemei Hu MD ,&nbsp;Shanyang He MD ,&nbsp;Gang Zhao MD ,&nbsp;Hujun Cui MD","doi":"10.1016/j.jvsv.2025.102350","DOIUrl":"10.1016/j.jvsv.2025.102350","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 1","pages":"Article 102350"},"PeriodicalIF":2.8,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145422171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of an automated, electronic medical record-integrated inferior vena cava filter tracking system on retrieval rates","authors":"Kathy L. Chan MD ,&nbsp;Paulina Sun MD ,&nbsp;Sudhir Rajan MD ,&nbsp;Gabriel Howles-Banerji MD, PhD ,&nbsp;Chi-Mei Liu PhD, MBA ,&nbsp;Marc Flagg BA ,&nbsp;Dongbin Todd BS ,&nbsp;Francis Bolanos BSIE ,&nbsp;Stephen L. Wang MD","doi":"10.1016/j.jvsv.2025.102351","DOIUrl":"10.1016/j.jvsv.2025.102351","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study was to evaluate the effects of an automated, electronic medical record (EMR)-integrated inferior vena cava (IVC) filter tracking system on retrieval rates across a large United States health care system.</div></div><div><h3>Methods</h3><div>A new, automated EMR-integrated IVC filter tracking system including individual filter plans, dwell time, and anticoagulation status was established across a United States health care system with 22 medical facilities. IVC filter utilization, rates of attempted retrieval, and mean dwell time were retrospectively analyzed between Januaray 2019 and January 2020.</div></div><div><h3>Results</h3><div>During the study period, filter use was 8.7 per 100,000 members, with 382 IVC filters placed. In statistical comparison to our 2016 study, implementation of this EMR-integrated tracking system increased regional attempted filter retrieval rates by 23.2% (38.9% to 62.1%; <em>P</em> &lt; .001, <span><math><mrow><mi>χ</mi></mrow></math></span>²) compared with a pretracking system of 427 patients with IVC filters deployed between December 2011 and January 2013. Compared with a web-based tracking system with physician education (347 IVC filters deployed from February 2013 to May 2014), implementation of this EMR-integrated tracking system increased regional attempted IVC filter retrieval rates by 8.1% (54% to 62.1%; <em>P</em> = .065, <span><math><mrow><mi>χ</mi></mrow></math></span>²). Both tracking systems were deployed within the same multifacility regional patient population. In further subanalysis of the EMR-integrated tracking system, among 335 retrievable devices placed, 209 were eligible for retrieval. Of 209 eligible retrieval filters, 169 had attempted retrieval (80.9%) with 165 successfully retrieved (78.9%).</div></div><div><h3>Conclusions</h3><div>Implementation of an EMR-integrated IVC filter tracking system was associated with increased eligible IVC filter retrieval rates across a large United States health care region to 80.9%, comparable to published rates at single facility centers with dedicated tracking programs. Similar results can be expected in other institutions and health care organizations since this tracking program was created within a widely used EMR.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 1","pages":"Article 102351"},"PeriodicalIF":2.8,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145409348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A synergistic multimodality treatment approach to address the key drivers of wound chronicity","authors":"Joann M. Lohr MD ,&nbsp;Joseph D. Raffetto MD ,&nbsp;David J. Dexter MD ,&nbsp;Matthew J. Regulski DPM ,&nbsp;Michael E. Edmonds MD ,&nbsp;Kathleen J. Ozsvath MD ,&nbsp;Melodie M. Blakely DPT","doi":"10.1016/j.jvsv.2025.102348","DOIUrl":"10.1016/j.jvsv.2025.102348","url":null,"abstract":"<div><h3>Background</h3><div>Chronic wounds remain a major clinical and economic burden, affecting millions worldwide. Despite advances in wound care, many wounds fail to heal due to persistent tissue hypoxia, unresolved inflammation, lymphatic dysfunction, edema, and ischemia-reperfusion injury. These interrelated mechanisms are further compounded by comorbidities such as obesity, diabetes, and vascular disease, highlighting the need for therapeutic approaches that address multiple barriers to repair simultaneously.</div></div><div><h3>Methods</h3><div>We review the pathophysiological drivers of wound chronicity—including the inflammation/edema/hypoxia cycle, endothelial dysfunction, and impaired lymphatic clearance—and summarize evidence on the roles of oxygen, nitric oxide, redox signaling, mechanotransduction, and specialized pro-resolving lipid mediators in tissue repair. We then evaluate two complementary, noninvasive interventions: topical oxygen therapy, which directly elevates wound tissue oxygen tension to support oxidative burst, angiogenesis, collagen synthesis, and specialized pro-resolving lipid mediator biosynthesis; and intermittent compression, which enhances lymphatic drainage, reduces edema, normalizes capillary gradients, and activates mechanosensitive repair pathways in endothelial cells, macrophages, fibroblasts, and keratinocytes.</div></div><div><h3>Results</h3><div>Chronic wound pathophysiology involves overlapping mechanisms of hypoxia, inflammation, edema, endothelial dysfunction, and reperfusion injury. Both topical oxygen therapy and intermittent compression independently improve oxygen delivery, perfusion, inflammation resolution, and tissue remodeling. When combined as intermittent topical oxygen therapy (ITOT), these modalities exert synergistic effects, amplifying oxygen bioavailability and potentiating anti-inflammatory, angiogenic, and reparative signaling. Clinical studies demonstrate that ITOT significantly increases healing rates, reduces healing time, lowers recurrence, and decreases hospitalizations and amputations in chronic wounds. Cost-effectiveness analyses further indicate improved quality-adjusted life years and reduced long-term expenditures.</div></div><div><h3>Conclusions</h3><div>Chronic wounds persist due to a self-sustaining cycle of hypoxia, edema, and inflammation. By integrating oxygen delivery with cyclical compression, ITOT directly addresses the multifactorial barriers to repair, promoting durable healing and reducing complications. This multi-modality approach represents a promising therapeutic advance in the management of refractory lower extremity wounds, with broad implications for improving outcomes and quality of life and reducing health care costs.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 1","pages":"Article 102348"},"PeriodicalIF":2.8,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145370442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renal angiomyolipoma with inferior vena cava/pulmonary thrombi","authors":"Tianyu Li MD,&nbsp;Yaru Zhu MD,&nbsp;Siyuan Lu MD,&nbsp;Jing Ye MD","doi":"10.1016/j.jvsv.2025.102349","DOIUrl":"10.1016/j.jvsv.2025.102349","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 1","pages":"Article 102349"},"PeriodicalIF":2.8,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145368282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"General and disease-specific quality-of-life improvement following superficial venous insufficiency treatment","authors":"Katherine Cappellano BA ,&nbsp;Maysie Calzon BS ,&nbsp;Sophia Weldon BS ,&nbsp;Esaan Azizi BS ,&nbsp;Jin-Ju Lee MPH ,&nbsp;Shravani Inampudi BS ,&nbsp;John Blebea MD, MBA ,&nbsp;Christopher Pittman MD, FAVLS, FACR, FACP (Hon)","doi":"10.1016/j.jvsv.2025.102347","DOIUrl":"10.1016/j.jvsv.2025.102347","url":null,"abstract":"<div><h3>Objective</h3><div>Most of the publications on the treatment of superficial venous insufficiency (SVI) have focused on technical and anatomic success. There are relatively few studies assessing patient-reported outcomes (PROs) after SVI treatment. However, patients and payers are increasingly interested in such outcomes in addition to technical success. We examined PROs after treatment with endovenous radiofrequency thermal ablation (RFA) and ultrasound-guided foam sclerotherapy (UGFS) for patients with SVI.</div></div><div><h3>Methods</h3><div>A retrospective chart review was performed on 545 consecutive patients with SVI treated between 2019 and 2024. Data on patient demographics, risk factors, Clinical-Etiology-Anatomy-Pathophysiology (CEAP) classification, Venous Clinical Severity Score (VCSS), and PROs were collected. The cohort was 395 female (73%) and 150 male (28%), with a median age of 62 years (mean 60 ± 14 years) and a median body mass index of 27 kg/m² (mean 28 ± 7 kg/m²). Most patients were White (n = 459, 84%), with 19 (4%) Black or African American, 7 (1%) Asian, and 39 (7%) other race; 21 (4%) declined to disclose. Prior venous disease was present in 382 patients (70%), whereas 163 (30%) had no history of venous disease. Patients completed two PROs, HASTI (Heaviness, Achiness, Swelling, Throbbing, Itching) and SF-6D (Short Form-6 Dimensions), before and after receiving treatment with RFA followed by UGFS. Data were analyzed using descriptive statistics and paired <em>t</em> tests to compare pre- and post-treatment outcomes.</div></div><div><h3>Results</h3><div>Most patients were women (72%), with an average age of 60 ± 14 years and an average body mass index of 28 ± 7. The average duration of symptoms before treatment was greater than 1 year, and the most common presenting symptoms included aches/pains, heaviness/tiredness, and cramping. Prior pregnancy was the most prominent risk factor for SVI, observed in 66% of female patients. All measures of HASTI and SF-6D showed improvements in symptom scores. VCSS also improved significantly, from 6.0 ± 2.9 to 3.9 ± 2.6 (<em>P</em> &lt; .001).</div></div><div><h3>Conclusions</h3><div>Treatment of SVI patients with RFA followed by UGFS significantly improves both disease-specific (HASTI) and general (SF-6D) quality-of-life measures in addition to a decrease in VCSS.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 1","pages":"Article 102347"},"PeriodicalIF":2.8,"publicationDate":"2025-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145368335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}