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PP2.2 – 00177 Late Increases in Intact Proviral DNA Reveal Variable HIV-1 Reservoir Dynamics
IF 3.5 4区 医学 Q2 IMMUNOLOGY Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100472
L. Brandt, S. Patro, W. Wang, N. Mckenna, E. Halvas, J. Cyktor, R.T. Gandhi, J. Eron, R. Bosch, M. Kearney, D. Mcmahon, J. Mellors
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引用次数: 0
7.2 – 00123 Peptide-induced apoptosis of latently infected cells and reduction of the HIV reservoir in people living with HIV: preliminary results of a clinical trial
IF 3.5 4区 医学 Q2 IMMUNOLOGY Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100431
R. Sobhie Diaz, M. Schechter, D. Elbirt, E. Naftali, J.T. Maricato, M.V. de Almeida Baptista, J. Galinskas, D. Dias, A. Bassini, N. Lisovoder, J.R. Hunter, E. Finkelshtein
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引用次数: 0
PP1.17 – 00054 Optimizing Detection of HIV-1 Infected Cells: A Novel Bioinformatics Pipeline Leveraging Kraken for Single-Cell Multiomics Datasets
IF 3.5 4区 医学 Q2 IMMUNOLOGY Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100466
L. Garrido-Sanz, L.B. Soriaga, E. Wong, M.C. Puertas, J. Dalmau, P. Coll, B. Mothe, B. Clotet, A. Telenti, J. Martinez-Picado, S. Morón-López
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引用次数: 0
4.2 – 00027 Secondary cytotoxicity of memory CD8+ T cells targeting autologous HIV during treated chronic infection is associated with suppression of provirus and of recrudescent viremia
IF 3.5 4区 医学 Q2 IMMUNOLOGY Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100413
D.R. Collins, M.J. Olatotse, E. Mazzola, M. Sagar, B.D. Walker, A. Tsibris
{"title":"4.2 – 00027 Secondary cytotoxicity of memory CD8+ T cells targeting autologous HIV during treated chronic infection is associated with suppression of provirus and of recrudescent viremia","authors":"D.R. Collins, M.J. Olatotse, E. Mazzola, M. Sagar, B.D. Walker, A. Tsibris","doi":"10.1016/j.jve.2024.100413","DOIUrl":"10.1016/j.jve.2024.100413","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 13-14"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143181416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP1.14 – 00005 Q4ddPCR - A New High-Throughput Multicolor Droplet Digital PCR Assay for Precise Intact Reservoir Quantification
IF 3.5 4区 医学 Q2 IMMUNOLOGY Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100463
R. Scheck, T.T. Huynh, M. Melzer, G. Gladkov, L. Buchauer, R.B. Jones, C. Gaebler
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引用次数: 0
PP3.4 – 00100 Retinoids enhance NK effector functions against HIV infected CD4 T cells
IF 3.5 4区 医学 Q2 IMMUNOLOGY Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100485
E. Mcmahon, R. Lynch, A. Bosque
{"title":"PP3.4 – 00100 Retinoids enhance NK effector functions against HIV infected CD4 T cells","authors":"E. Mcmahon, R. Lynch, A. Bosque","doi":"10.1016/j.jve.2024.100485","DOIUrl":"10.1016/j.jve.2024.100485","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Page 62"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143134584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP3.5 – 00089 Investigating novel designed and synthesized PKC modulators for use in “kick and kill” HIV cure strategies
IF 3.5 4区 医学 Q2 IMMUNOLOGY Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100486
J. Morán, Z. Gentry, O. Mcateer, J. Hamad, J.T. Kim, P. Wender, J. Zack, M. Marsden
{"title":"PP3.5 – 00089 Investigating novel designed and synthesized PKC modulators for use in “kick and kill” HIV cure strategies","authors":"J. Morán, Z. Gentry, O. Mcateer, J. Hamad, J.T. Kim, P. Wender, J. Zack, M. Marsden","doi":"10.1016/j.jve.2024.100486","DOIUrl":"10.1016/j.jve.2024.100486","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 62-63"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143135196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP3.7 – 00002 Towards a functional cure for HIV-1 infection: BRD4 modulator ZL0580 and LEDGINs additively block and lock HIV-1 transcription
IF 3.5 4区 医学 Q2 IMMUNOLOGY Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100488
E. Pellaers, A. Denis, W. Hannes, A. Bhat, Z. Debyser
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引用次数: 0
1.3 – 00084 Persistence of HIV genomes in bacteria-specific CD4+ T cells during ART
IF 3.5 4区 医学 Q2 IMMUNOLOGY Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100396
A. Espinosa Ortiz, R. Fromentin, S.G. Deeks, J.P. Routy, N. Chomont
{"title":"1.3 – 00084 Persistence of HIV genomes in bacteria-specific CD4+ T cells during ART","authors":"A. Espinosa Ortiz, R. Fromentin, S.G. Deeks, J.P. Routy, N. Chomont","doi":"10.1016/j.jve.2024.100396","DOIUrl":"10.1016/j.jve.2024.100396","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Page 2"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143176159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bypassing primary antiretroviral therapy centres in Sub-Saharan Africa: An integrative review of the theoretical and empirical literature
IF 3.5 4区 医学 Q2 IMMUNOLOGY Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100580
Maximillian Kolbe Domapielle , Sadat Zakari Abugbila , Marshall Kala
The uptake of antiretroviral therapy (ART) is critical to meeting the global HIV treatment goal of 95-95-95 by 2025. Although a few Sub-Saharan African countries have already achieved this target, the prevalence of bypassing primary ART centres in many countries in the subregion has negative implications for ART uptake and use. This study used the access to health services framework to analyse the evidence and factors contributing to bypassing primary ART centres by individuals in the sub-region seeking HIV care and support. We found compelling evidence of the prevalence of ART clients bypassing their primary ART centres in search of specialised care in higher-tiered health facilities. Others use bypassing to conceal their HIV-positive status to avoid social stigma. We argue that introducing specialised and differentiated ART at the primary level of care can address this phenomenon. While we anticipate that this measure will satisfy clients' desire for specialised care, we recommend enhancing public awareness about the effectiveness of ART to reduce stigma towards ART clients. Legislation and strict enforcement of anti-HIV stigma laws, which outlaw and criminalise stigmatising people living with HIV (PLHIV), could potentially be an effective stigma-deterring measure. To complement this effort, PLHIV should be empowered to understand legislative instruments and steps to take when confidentiality and discriminatory issues arise. We recommend further research in Sub-Saharan Africa to investigate the relationship between bypassing primary ART centres and client adherence. The findings will help design appropriate strategies to increase ART uptake at primary ART centres.
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引用次数: 0
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Journal of Virus Eradication
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