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Diagnostic Evaluation of a Multiplex Quantitative Real-Time PCR Assay forBacterial Vaginosis 多重实时荧光定量PCR检测对细菌性阴道病的诊断价值
Pub Date : 2016-01-27 DOI: 10.4172/2167-0420.1000293
N. Dhiman, Charles J Yourshaw, M. Chintalapudi, C. Turner, E. Murphy
Background: Quantitative multiplex PCR assay for Bacterial Vaginosis (BV) based on the detection of the predominant contributory targets was evaluated against the conventional Nugent Score that is laborious and subjective due to morphological assessment bias of BV-associated bacteria. Methods: 125 dual vaginal specimens were collected from patients aged ≥18 years at the time of presentation at the provider office to perform real time PCR and Nugent Testing. PCR assessment of BV was performed by quantitation of DNA amounts of Gardnerella vaginalis, Atopobium vaginae, Lactobacillus spp., and total amount of bacterial DNA using a multiplex RT-PCR kit (ATRiDA, Netherlands). Discordant results were resolved by the Amsel criteria or ancillary testing such as BD Affirm, when available. Results: Nugent score classified 36.36% of the patients in BV and 15.45% in transitional BV categories. In contrast, the PCR method called 48.18% as BV and 12.72% as transitional BV or BV of unspecified origin categories. The overall concordance between the two methods was 81.81%. None of the BV positives by Nugent method were missed by the PCR. There were only 2 intermediates by Nugent that were called normal by PCR. PCR method was more sensitive than the Nugent and picked an additional 11% positives. Conclusions: PCR based molecular BV diagnosis can standardize women health testing by removing the bias due to subjective interpretation of Nugent scoring. Our study shows that PCR method is more sensitive than conventional testing and may be a promising replacement for laborious Nugent scoring method in an era of shrinking microbiology expertise.
背景:对细菌性阴道病(BV)的多重定量PCR检测方法进行了评估,该方法基于检测主要的贡献靶点,而传统的纽金特评分法由于细菌性阴道病相关细菌的形态学评估偏差,既费力又主观。方法:从就诊时年龄≥18岁的患者中采集双阴道标本125份,进行实时PCR和Nugent检测。采用多重RT-PCR试剂盒(ATRiDA,荷兰)对阴道加德纳菌、阴道托波菌、乳杆菌的DNA量和细菌DNA总量进行定量,对细菌性阴道炎进行PCR评估。不一致的结果通过Amsel标准或辅助测试(如BD Affirm)解决。结果:Nugent评分对BV的分类为36.36%,对过渡性BV的分类为15.45%。相比之下,PCR方法为48.18%为BV, 12.72%为过渡性BV或未确定来源类别的BV。两种方法的总体一致性为81.81%。Nugent法检测的BV阳性均未被PCR遗漏。只有2个Nugent的中间产物被PCR称为正常。PCR法比纽金特法更敏感,并额外挑选出11%的阳性。结论:基于PCR的BV分子诊断可消除Nugent评分主观解释的偏差,使女性健康检测标准化。我们的研究表明,PCR方法比传统检测更敏感,在微生物学专业知识萎缩的时代,可能是费力的纽金特评分法的有希望的替代品。
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引用次数: 3
Knowledge, Attitudes and Practices towards Risky Sexual Behaviors among Adolescents of Jimma University Community High School, South West Ethiopia, 2015 吉玛大学社区高中青少年对危险性行为的知识、态度和行为,埃塞俄比亚西南部,2015
Pub Date : 2016-01-25 DOI: 10.4172/2167-0420.1000292
L. Ena, Bekana Fekecha Hurissa, S. Aliyu
Background: Sexual activities among adolescents have been reported as increasing worldwide. Risky sexual behaviors are among the factors that increase the likelihood of adverse sexual and reproductive health consequences such as unwanted pregnancies, unsafe abortion, STIs including HIV/AIDS and others. Adolescents in sub-Saharan Africa including Ethiopia are highly exposed to various risky sexual behaviors. Objective: To assess knowledge, attitude and practice towards risky sexual behaviors among adolescents of Jimma university community high school Methods: A cross-sectional study was conducted. Total sample size of the study was selected by using stratified random sampling technique with proportional allocation to size of each stratum. Data was collected using structured, pre-tested self-administered questionnaire. Data was analyzed by using chi-square and p value less than 0.05 was considered forstatically significant. Result: Majority of the respondents 73.8% knew about risks of sexual behaviors. Above 1/3 (34.93%) of them got information about sexual matter from parents.76.86% had good knowledge about risky sexual behavior. About 32.75% of them had at least one sexual intercourse before the study. Among them, 27.07% had sex 3 months prior to the study, out of which only 43.55% used condom and 36 (58.06%) had sex with multiple partners; 6.11% &15.72% practiced homosexuality and masturbation respectively. Conclusion: There was high practice of sexual activity, high prevalence of premarital sex, low utilization of condom and contraceptives and only around half of the participants thought that condom prevents HIV/AIDS.
背景:据报道,青少年的性行为在世界范围内呈上升趋势。危险的性行为是增加诸如意外怀孕、不安全堕胎、包括艾滋病毒/艾滋病在内的性传播感染等不良性健康和生殖健康后果的可能性的因素之一。包括埃塞俄比亚在内的撒哈拉以南非洲的青少年高度暴露于各种危险的性行为。目的:了解吉马大学社区高中青少年对危险性行为的认知、态度和行为。本研究的总样本量采用分层随机抽样技术,根据各层的大小按比例分配。数据收集采用结构化的,预先测试的自我管理问卷。数据采用卡方分析,p值小于0.05认为具有统计学意义。结果:绝大多数被调查者(73.8%)知晓性行为风险。超过1/3(34.93%)的青少年从父母处获得性知识,76.86%的青少年对危险性行为有良好的认识。约32.75%的人在研究前至少有过一次性行为。其中,27.07%的人在研究前3个月有过性行为,其中使用安全套的占43.55%,有多个性行为的占36例(58.06%);分别有6.11%和15.72%的人有同性恋行为和手淫行为。结论:性行为频度高,婚前性行为发生率高,安全套和避孕药具使用率低,只有约一半的参与者认为安全套可以预防艾滋病。
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引用次数: 5
One, 5 and 10 Year Net Survival Rates for Male and Female Bladder Cancer Patients; Why are they so Different? 男性和女性膀胱癌患者1年、5年和10年的净生存率为什么他们如此不同?
Pub Date : 2015-12-28 DOI: 10.4172/2167-0420.1000291
M. Ruddock, Cherith N. Reid, J. Lamont, S. Fitzgerald
The most common symptom of bladder cancer is blood in the urine (haematuria), which is usually painless. Haematuria can be frank (macroscopic), visible to the patient, or invisible (microscopic), which is normally detected during a routine urine dipstick test. Haematuria in its visible and invisible forms can represent a disease process within the urinary tract. These diseases can range from benign causes to malignant causes such as bladder cancer. Indeed, it is common for no obvious cause to be identified after detailed investigations. These investigations include cystoscopy, cytology and radiological imaging of the upper urinary tract. In many cases, there are significant delays in diagnosing bladder cancer in women as many women ignore the most basic symptom, haematuria which they often associate with menstruation or menopause. Furthermore, even after the problem has been reported to their GP, haematuria can still be misdiagnosed as cystitis or a urinary tract infection. Women are less likely than men to undergo a complete and timely evaluation for haematuria. As such, there can be a significant delay in a bladder cancer diagnosis. Late diagnosis and developing rare forms of the disease are among the possible factors which may explain the disparity between male and female bladder cancer survival rates.
膀胱癌最常见的症状是尿中带血(血尿),通常无痛。血尿可以是肉眼可见的(肉眼可见),也可以是肉眼不可见的(显微镜下可见),通常在常规尿试纸试验中可以检测到。可见和不可见形式的血尿可以代表尿路内的疾病过程。这些疾病可以是良性的,也可以是恶性的,比如膀胱癌。事实上,在详细调查后没有发现明显的原因是很常见的。这些检查包括膀胱镜检查、细胞学检查和上尿路影像学检查。在许多情况下,诊断女性膀胱癌有很大的延迟,因为许多女性忽视了最基本的症状,血尿,这通常与月经或更年期有关。此外,即使问题已经报告给他们的全科医生,血尿仍然可能被误诊为膀胱炎或尿路感染。女性比男性更不可能接受完整和及时的血尿评估。因此,膀胱癌的诊断可能会有很大的延迟。晚期诊断和发展为罕见形式的疾病是可能解释男性和女性膀胱癌存活率差异的因素之一。
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引用次数: 3
Blood Glucose Levels and Pregnancy Outcome in a High-risk Population 高危人群的血糖水平与妊娠结局
Pub Date : 2015-12-18 DOI: 10.4172/2167-0420.1000289
L. B. A. Ketbi, N. Nagelkerke, H. Mirghani
Objectives: UAE pregnant women have a higher prevalence, of metabolic disorders such as insulin resistance, obesity, diabetes and gestational diabetes. This justifies outcome mapping in relation to blood sugar. Research Design and Methods: A hundred ninety-eight healthy UAE pregnant women enrolled in primary health care centers in 2010-2011 were followed in the hospital for outcome of pregnancy. Methods: Retrospective chart review, Surveyed exposure variables: demographic data, obstetric history, BMI, Blood pressure, Hemoglobin, early trimester glucose levels fasting and 1hr after breakfast, second trimester OGTT. Primary outcomes were: gestational age at delivery, mode of delivery, fetal weight, and baby admission to SCABU or death. Results: A non-significant trend between birth weight and the different glucose levels was found. Surprisingly, small for gestational age babies are seen in mothers with lower 1 hr OGTT. FBS OGTT was associated with the occurrence of pregnancy complications as PET (p<0.012). Only mothers with high BMI and parity appear more likely to have larger babies (p< 0.008, p<0.038). Delivery complications were more common in older women and those with lower parity (p<0.034, p<0.013), GDM was more common in obese women (p<0.033) and 1 hour OGTT with 2 hr OGTT, FBS OGTT and increasing age (p<0.00001, p<0.008, p<0.012). Conclusion: OGTT was not helpful in predicting outcome in this population. Large Birth weight babies were not more common in women with higher glucose levels but obesity was associated with larger babies significantly.
目的:阿联酋孕妇有较高的代谢紊乱患病率,如胰岛素抵抗、肥胖、糖尿病和妊娠糖尿病。这证明了与血糖相关的结果映射是合理的。研究设计和方法:2010-2011年在初级卫生保健中心登记的198名健康的阿联酋孕妇在医院随访妊娠结局。方法:回顾性图表复习,调查暴露变量:人口统计学资料、产科史、BMI、血压、血红蛋白、妊娠早期空腹及早餐后1小时血糖水平、妊娠中期OGTT。主要结局是:分娩时胎龄、分娩方式、胎儿体重、婴儿SCABU入院或死亡。结果:出生体重与不同血糖水平之间无显著趋势。令人惊讶的是,低1小时OGTT的母亲出现了胎龄较小的婴儿。FBS OGTT与妊娠并发症的发生呈正相关(p<0.012)。只有高体重指数和胎次的母亲更有可能生出更大的婴儿(p< 0.008, p<0.038)。分娩并发症以高龄和低胎次妇女多见(p<0.034, p<0.013), GDM以肥胖妇女多见(p<0.033), 1小时OGTT与2小时OGTT、FBS OGTT和年龄增加多见(p<0.00001, p<0.008, p<0.012)。结论:OGTT对预测该人群的预后没有帮助。出生时体重大的婴儿在血糖水平较高的女性中并不常见,但肥胖与体重大的婴儿显著相关。
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引用次数: 3
Level of Awareness on Danger Signs of Pregnancy among Pregnant Women Attending Antenatal Care in Mizan Aman General Hospital, Southwest, Ethiopia: Institution Based Cross-sectional Study 埃塞俄比亚西南部Mizan Aman总医院产前护理孕妇对妊娠危险体征的认识水平:基于机构的横断面研究
Pub Date : 2015-12-10 DOI: 10.4172/2167-0420.1000288
Eskedar Demissie, Fantahun Dessie, F. W. Michael, Tensay Kahsay, Niguse Tadele
Back ground: Every pregnant woman faces the risk of sudden, unpredictable complication that could end in death or injury to mother or infant. Danger signs of pregnancies are warning signs that women encounter during pregnancy, child birth and postpartum. It is important, to know this warning signs for women. The most common danger signs are: vaginal bleeding, convulsions, abdominal pain, severe headaches, blurred vision, and absence of fetal movements and gush of fluid from vagina. This study aimed at to assess level of awareness on danger signs of pregnancy among women attending antenatal care (ANC) in Mizan Aman General Hospital (MAGH), Southwestern, Ethiopia. Methods: Institutional based cross sectional study was conducted in May 2014. A total of 358 pregnant mothers were included in the study. Systematic random sampling technique was used to select study participants at the exit of ANC service, face to face interviewer technique was used to collect data and descriptive analyze was done. Result: This study shows that 53% of the study participants have poor awareness on danger signs of pregnancy. Educational status, member of ANC visit and occupation of the mother are factors that affect the level of awareness. As education level increase awareness of the mother also increase, 69% of respondent who were at high school and above were aware, while only 10.2% of illiterate have good awareness on danger sign of pregnancy. The study shows government employee are more aware 30.56% than house wives 12.23% and as the number of ANC visit increase the awareness of the mother also increase. Conclusion: Mother’s awareness on danger signs of pregnancy was poor and affected by educational status, ANC follow up and occupation. Therefore women must empower to get education by the government. Medias shall better to give health education related to danger signs of pregnancy.
背景:每个孕妇都面临着突发的、不可预测的并发症的风险,这些并发症可能导致母亲或婴儿死亡或受伤。怀孕的危险信号是妇女在怀孕、分娩和产后遇到的警告信号。了解这些对女性的警告信号是很重要的。最常见的危险迹象是:阴道出血、抽搐、腹痛、剧烈头痛、视力模糊、胎动停止和阴道涌出液体。本研究旨在评估在埃塞俄比亚西南部米赞阿曼总医院(MAGH)接受产前护理(ANC)的妇女对怀孕危险迹象的认识水平。方法:于2014年5月进行基于机构的横断面研究。共有358名孕妇参与了这项研究。本研究采用系统随机抽样技术,在非国大服务退出时选择研究参与者,采用面对面访谈技术收集数据并进行描述性分析。结果:这项研究表明,53%的研究参与者对怀孕的危险迹象缺乏认识。教育程度、非国大成员访问和母亲职业是影响认识水平的因素。随着受教育程度的提高,对母亲的认识也在提高,69%的高中及以上学历的受访者对怀孕危险信号有良好的认识,而文盲中只有10.2%的人对怀孕危险信号有良好的认识。该研究显示,30.56%的政府雇员比12.23%的家庭主妇更清楚这一点,随着ANC访问次数的增加,母亲的意识也在提高。结论:产妇对妊娠危险体征的认识较差,且受文化程度、ANC随访及职业的影响。因此,政府必须赋予妇女接受教育的权利。媒体应加强对怀孕危险迹象的健康教育。
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引用次数: 28
Breast Fibroadenoma and Uterine Fibroid in a Female with HACEK Endocarditis: Is there any Possible Correlation? 女性HACEK心内膜炎患者的乳腺纤维腺瘤和子宫肌瘤:是否有可能的相关性?
Pub Date : 2015-12-04 DOI: 10.4172/2167-0420.1000287
Xeiad Cerrag
Women health care is stereotypically epitomized and confined to women’s reproductive and maternal capacities which tackle only a tiny portion of women’s general health. Studying diseases with salient female predilections and/ or provoke feminine manifestations should be fitted snugly into a coherent database system toward finding effective policies in treating such afflicted population. Autoimmune diseases and microbial pathoses are blatant examples of risky diseases which are encountered strikingly in females. Linking the dots, this paper reports a breast fibro adenoma and concomitant two uterine fibroids of the anterior wall in a 22-year-old female with HACEK endocarditis. This report is ushered to capture the clinician’s rapt attention to such a plausible association.
妇女保健照例集中于妇女的生殖和孕产能力,只涉及妇女一般健康的一小部分。研究具有明显女性偏好和(或)引起女性症状的疾病应紧密结合到一个连贯的数据库系统中,以便找到治疗这些患病人口的有效政策。自身免疫性疾病和微生物病是女性明显遇到的危险疾病的明显例子。本文报道了一例22岁女性HACEK心内膜炎患者的乳腺纤维腺瘤和伴发的前壁两个子宫肌瘤。本报告旨在引起临床医生对这种似是而非的联系的全神贯注的注意。
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引用次数: 1
OHSS Complicated With PID and Pelvic Abscess after IVF in a 35 Year Old Woman: A Case Report and Review of the Literature 35岁女性体外受精后OHSS合并盆腔脓肿1例报告及文献复习
Pub Date : 2015-11-30 DOI: 10.4172/2167-0420.1000285
S. Stavrou, E. Domali, D. Loutradis, P. Drakakis
Background: Ovarian hyper stimulation syndrome is an iatrogenic serious complication that presents after human chorionic gonadotropin stimulation or after the spontaneous peak of luteizing hormone. Pelvic inflammatory disease following the in vitro fertilization and oocyte retrieval is a rare and infrequent complication. Tubo-ovarian abscess has been described as rare and significant complication .We present an uncommon case according the literature in which rare complications of IVF are described. Methods: We present a case of a 35 year old female patient, gravida 1, para 0 with history of in vitro fertilization short protocol and oocytes retrieval before a month ,attended our hospital complaining for deep abdominal pain since 8 days with significant gynecological past history. Clinical evaluation proved abdominal pain on palpation without fever. Serum levels of C-reactive protein were significantly elevated reaching the plateau of 320,943. Results: Transvaginal ultrasonography noticed the presence of a big left adnexal formation max diameter 18 cm that could be attributed to marked inflammation. Behind this, free fluid detected by the presence of adhesions that could be attributed to hydrosalpinx. The diagnosis of ovarian hyper stimulation syndrome followed by pelvic inflammatory disease was made and she hospitalized for 10 days. The patient came to our hospital 3 months later for her follow up and the transvaginal examination revealed left tubo-ovarian abscess. A new transvaginal ultrasonography after 3 months was clearly improved compared to the previous images. Conclusion: Ovarian hyper stimulation syndrome which is complicated with pelvic inflammatory disease and especially pelvic abscess after in vitro fertilization and oocyte retrieval guided by ultrasound is a rare and simultaneously significant complication. Transvaginal ultrasonographical examination seems to be a pivotal tool primarily for the diagnosis and secondarily for the follow up of these infertile women.
背景:卵巢过度刺激综合征是人绒毛膜促性腺激素刺激或促黄体激素自发高峰后出现的医源性严重并发症。体外受精和卵母细胞回收后的盆腔炎是一种罕见的并发症。输卵管卵巢脓肿是一种罕见而重要的并发症,我们根据文献报道一例罕见的病例,其中描述了IVF的罕见并发症。方法:我们报告一例35岁女性患者,妊娠1期,第0期,有体外受精短方案史,1个月前取卵,主诉深腹痛8天来我院就诊,有明显妇科病史。临床评价证实触诊腹痛,无发热。血清c -反应蛋白水平显著升高,达到平台值320,943。结果:经阴道超声检查发现左侧附件有一个最大直径18cm的大肿块,可能是明显的炎症。在这背后,自由液体检测到粘连的存在,可能归因于输卵管积水。诊断为卵巢过度刺激综合征并发盆腔炎,住院10天。3个月后患者来我院随访,经阴道检查发现左侧输卵管卵巢脓肿。3个月后的新阴道超声检查与以前的图像相比明显改善。结论:超声引导下体外受精取卵后并发盆腔炎尤其是盆腔脓肿的卵巢过度刺激综合征是一种罕见且重要的并发症。经阴道超声检查似乎是一个关键的工具,主要是诊断,其次是对这些不孕妇女的随访。
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引用次数: 1
Risky Sexual Behaviors for HIV Infection among Female Private College Students in Nekemte Town, Western Ethiopia 埃塞俄比亚西部Nekemte镇私立女大学生的高危性行为感染艾滋病毒
Pub Date : 2015-10-28 DOI: 10.4172/2167-0420.1000284
Benti Negero Feyisa, E. T. Bala
Background: HIV/AIDS risky behavior remains a critical health concern for young women for multiple biological and socio-economic reasons. Hence, the objective of the study was to assess the level of risky sexual behaviors and associated factors among female students in private colleges in Nekemte town, western Ethiopia. Methods: A cross-sectional study was carried out among female private college students in Nekemte town between April and May, 2014. A total of 422 female students in private colleges were randomly selected for the study. A self-administered questionnaire was used for data collection. The collected data were cleaned and analyzed using SPSS version 16. Bivariate and multivariable analyses were done to identify predictors of risky sexual behaviors. Results: One hundred fifty six (38.4%) of the non-married (N=406) respondents had practiced sexual intercourse. Of these, 115(73.7%) were sexually active in the last 12 months. Of the total respondents who were sexually active in the last 12 months including the married one (N=131), 38(29%) reported that they had sexual intercourse with two or more partners. Among non-married females who were sexually active in the last 12 months (N=115), only 34(29.6%) reported to have used condom at their last sexual intercourse. Urban residence (AOR=2.4, 95% CI =1.3, 4.5), income deficit (AOR= 2.8, 95 % CI=1.5, 4.0), Income source (AOR=2.5, 95% CI=2.0, 9.0) and pornographic film viewing (AOR=10.7, 95 % CI=5.1, 22.5) were significantly associated with premarital sex. Level of study (AOR =2.0, 95% CI=1.3, 3.2), marital status AOR=2.8, 95% CI 1.8, 6.6), Living arrangement (AOR= 3.295% CI=1.3, 4.5, and pornographic viewing (AOR=2.0, 95% CI=1.1, 4.3 were significantly associated with multiple sexual partners. Similarly, condom use in the last sexual intercourse among nonmarried female students was significantly associated with level of study (AOR= 0.2, 95 % CI= 0 .1-0.9), Knowledge of HIV prevention by consistent use of condoms (AOR=2.9, 95%CI 1.0-8.0), pornographic viewing AOR= 2.7, 95 % CI =1.0, 7.6) and alcohol drinking (AOR=5.2, 95 % CI 3.2, 7.3). Conclusion: This study indicated that large proportions of students were engaged in risky sexual behaviors. Hence, Encouraging continuation of virginity as a cultural norm among those who have not experienced sexual intercourse and awareness creation.
背景:由于多种生物学和社会经济原因,艾滋病毒/艾滋病危险行为仍然是年轻妇女的一个严重健康问题。因此,本研究的目的是评估埃塞俄比亚西部Nekemte镇私立大学女学生的危险性行为水平及其相关因素。方法:对2014年4 - 5月Nekemte镇民办女大学生进行横断面调查。随机抽取422名私立高校女学生进行研究。数据收集采用自填问卷。收集的数据使用SPSS version 16进行清理和分析。进行了双变量和多变量分析,以确定危险性行为的预测因素。结果:在406名未结婚的调查对象中,有性交行为的有156人(38.4%)。其中,115人(73.7%)在过去12个月内性活跃。在过去12个月内性活跃(包括已婚人士)的受访者中,有38人(29%)表示曾与两个或两个以上的伴侣发生过性行为。在过去12个月内性活跃的未婚女性(N=115)中,只有34人(29.6%)报告在最后一次性交时使用了安全套。城市居住(AOR=2.4, 95% CI= 1.3, 4.5)、收入不足(AOR= 2.8, 95% CI=1.5, 4.0)、收入来源(AOR=2.5, 95% CI=2.0, 9.0)和观看色情电影(AOR=10.7, 95% CI=5.1, 22.5)与婚前性行为显著相关。研究水平(AOR=2.0, 95% CI=1.3, 3.2)、婚姻状况AOR=2.8, 95% CI 1.8, 6.6)、生活安排(AOR= 3.295% CI=1.3, 4.5)和色情观看(AOR=2.0, 95% CI=1.1, 4.3)与多个性伴侣显著相关。同样,未婚女学生在最后一次性交中使用安全套的程度与学习水平(AOR= 0.2, 95%CI = 0.1 -0.9)、通过持续使用安全套预防艾滋病毒的知识(AOR=2.9, 95%CI 1.0-8.0)、观看色情内容(AOR= 2.7, 95%CI =1.0, 7.6)和饮酒(AOR=5.2, 95%CI 3.2, 7.3)显著相关。结论:本研究表明大学生存在危险性行为的比例较大。因此,鼓励那些没有经历过性行为和提高认识的人继续保持贞操作为一种文化规范。
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引用次数: 2
Implants Contraceptive Utilization and Factors Associated among Married Women in the Reproductive Age Group (18-49 Year) in Southern Ethiopia 埃塞俄比亚南部育龄已婚妇女(18-49岁)避孕药具的利用及其相关因素
Pub Date : 2015-10-28 DOI: 10.4172/2167-0420.1000281
B. Elias, Tesfahun Hailemariam
Background: Implants contraceptive are one of the most effective reversible modern contraceptive methods. Implants can be used by women from menarche to menopause. Many women can safely use implants including lactating mothers, HIV positive women, cigarette smokers of any age, post abortion women, diabetic women, women at risk for cardiovascular disease (including those with high blood pressure), and adolescents.Methods: A community based cross-sectional study was conducted among married women aged 18-49 years in East Badewacho Woreda, Southern Ethiopia. Multistage sampling technique was used to select a total of 647 study participants. A pre-tested structured questionnaire was used for data gathering. For data entry Epi-info version 3.5.1 was used and bivariate and multivariate logistic regression analyses were performed using SPSS version 16.0 statistical package. Results: The implant contraceptive prevalence rate among married women is 96(15.1%). Implanon contraceptives were the most frequently used methods 51(53.1%), sino-implanol 29(30.2%) and jadelle 16(16.7%). Multiple logistic regression model revealed that the husband approval (AOR 3.07, 95% CI 1.64-5.74), joint decision (AOR 5.65, 95% CI 2.78-11.51), married women who have income (AOR 2.74, 95% CI 1.26-5.95), joint discussion (AOR 6.53, 95% CI 3.10-13.77). Similarly, age, disscussed with health workers and health development army leaders were significantly associated with the use of implant contraceptives. Conclusion: Implant contraceptive utilization is high in the woreda as compared to other methods. Joint decision, joint discussion, discussed with health workers and health development army leaders, husband approval of contraceptive use were significantly associated with the use of implant contraceptives. Therefore, woreda health office and concerned bodies be supposed to focus on couple’s communication, male involvement and community conversation with health worker and health development army leaders that could enhance implant contraceptive utilization.
背景:植入避孕是最有效的可逆现代避孕方法之一。从月经初潮到更年期的女性都可以使用植入物。许多妇女可以安全地使用植入物,包括哺乳期母亲、艾滋病毒阳性妇女、任何年龄的吸烟者、堕胎后妇女、糖尿病妇女、有心血管疾病风险的妇女(包括高血压妇女)和青少年。方法:对埃塞俄比亚南部东部Badewacho worreda地区18-49岁的已婚妇女进行了一项基于社区的横断面研究。采用多阶段抽样技术,共选取647名研究对象。采用预先测试的结构化问卷进行数据收集。数据录入采用Epi-info 3.5.1版本,双变量和多变量logistic回归分析采用SPSS 16.0版本统计软件包。结果:已婚妇女植入避孕普及率为96(15.1%)。最常用的避孕方法为植入避孕药51例(53.1%),其次为中-植入避孕药29例(30.2%),贾德尔避孕药16例(16.7%)。多元logistic回归模型显示,丈夫认可(AOR 3.07, 95% CI 1.64-5.74)、共同决定(AOR 5.65, 95% CI 2.78-11.51)、已婚女性有收入(AOR 2.74, 95% CI 1.26-5.95)、共同讨论(AOR 6.53, 95% CI 3.10-13.77)。同样,与卫生工作者和卫生发展部队领导人讨论的年龄与使用植入性避孕药具显著相关。结论:与其他避孕方法相比,女性避孕药具的使用率较高。与卫生工作者和卫生发展部队领导人共同决定、共同讨论、丈夫批准使用避孕药具与使用植入性避孕药具显著相关。因此,卫生办公室和有关机构应注重与卫生工作者和卫生发展部队领导人的夫妻沟通、男性参与和社区对话,以提高植入避孕药具的利用率。
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引用次数: 12
Materno-fetal Outcomes in Patients with Abnormally Invasive Placenta: A 14 Year Experience 异常侵入性胎盘患者的母胎结局:一项14年的经验
Pub Date : 2015-09-28 DOI: 10.4172/2167-0420.1000286
L. Fali, Yogender Yadav, Maharaj Dushyant, A. Peter, P. Gordon, Tait John, E. Rose
Objectives: To establish the incidence of abnormally invasive placenta (AIP); determine trends in the diagnosis and management; and assess maternal and neonatal morbidity associated with AIP. Methods: Women were identified from a tertiary care referral hospital perinatal database (2000-2013) and crosschecked with confirmed histopathology. Verification of undetected cases using perinatal ultrasound database was performed. Risk factors, antenatal suspicion, hospital course, intrapartum management, maternal and neonatal outcomes were obtained from medical records. Results: Thirty eight women had AIP confirmed providing an incidence of 1 per 1420 deliveries. The incidence rose by 55% (95% Confidence interval (CI) 37% - 279%) over the 14 year period (Poisson regression). An antenatal diagnosis of AIP was made in 63% (95% CI 46% - 78%). Excluding women with placenta percreta, there was a significantly higher blood loss in women in whom an attempt was made at placental removal compared to women in whom there was no attempt (median 3.5 liters versus 1.5 L, p=0.002). Conclusion: AIP was associated with significant maternal and neonatal morbidity. A significantly higher blood loss ensued in women with AIP in whom an attempt was made at placental separation. A dedicated multidisciplinary team and a standardized pathway can potentially reduce morbidity.
目的:了解异常侵入性胎盘(AIP)的发生率;确定诊断和管理的趋势;评估与AIP相关的孕产妇和新生儿发病率。方法:从三级转诊医院围产期数据库(2000-2013年)中确定妇女,并与确认的组织病理学交叉核对。利用围产期超声数据库对未检出病例进行验证。从医疗记录中获取风险因素、产前怀疑、住院过程、产时管理、孕产妇和新生儿结局。结果:38名妇女确诊为AIP,发生率为1 / 1420次分娩。在14年期间,发病率上升了55%(95%置信区间(CI) 37% - 279%)(泊松回归)。产前诊断为AIP的比例为63% (95% CI 46% - 78%)。排除有percreta胎盘的女性,尝试移除胎盘的女性的失血量明显高于未尝试移除胎盘的女性(中位数为3.5升对1.5升,p=0.002)。结论:AIP与孕产妇和新生儿发病率有显著相关性。在尝试胎盘分离的AIP妇女中,出血量明显增加。一个专门的多学科团队和标准化的途径可以潜在地降低发病率。
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引用次数: 1
期刊
Journal of Womens Health Care
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