Pub Date : 2017-07-20DOI: 10.11150/kansenshogakuzasshi.91.568
Kenichi Hayashi, Yukihiro Yamaguchi
{"title":"A Case of a Vesico-Pubic Fistula due to Tuberculous Osteomyelitis of the Pubic Bone","authors":"Kenichi Hayashi, Yukihiro Yamaguchi","doi":"10.11150/kansenshogakuzasshi.91.568","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.91.568","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88487345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-20DOI: 10.11150/KANSENSHOGAKUZASSHI.91.399
N. Hayashi, Y. Nojima, Takatsuka Takeshi, Masayuki Yanagisawa, Etsuko Utakawa
{"title":"A Study on the Scattering Situation of Vomitus to Assess Extended Preventive Measures Against Norovirus Infectious Diseases in a Hospital or Nursing Facility","authors":"N. Hayashi, Y. Nojima, Takatsuka Takeshi, Masayuki Yanagisawa, Etsuko Utakawa","doi":"10.11150/KANSENSHOGAKUZASSHI.91.399","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.91.399","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81705125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-20DOI: 10.11150/KANSENSHOGAKUZASSHI.91.416
Kei Yamamoto, M. Nagamatsu, Sunao Takeuchi, S. Kutsuna, Nozomi Takeshita, K. Hayakawa, Y. Kato, Shuzo Kanagawa, N. Ohmagari
{"title":"A Recurrent Skin Lesion Probably Associated with Helicobacter c inaedi","authors":"Kei Yamamoto, M. Nagamatsu, Sunao Takeuchi, S. Kutsuna, Nozomi Takeshita, K. Hayakawa, Y. Kato, Shuzo Kanagawa, N. Ohmagari","doi":"10.11150/KANSENSHOGAKUZASSHI.91.416","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.91.416","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78456293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-20DOI: 10.11150/KANSENSHOGAKUZASSHI.91.376
Yasuo Kaburagi, H. Ueno, A. Kaetsu, K. Tomari, K. Kikuchi, S. Kobori, M. Miyazaki
Human enterovirus D68 (EV-D68) is a member of the Enterovirus genus (EVs) within the Picornaviridae family, and generally associated with respiratory tract infection. Meanwhile, previous reports suggest that EV-D68 was also associated with acute flaccid paralysis in the clinical cases in USA and Japan. Two conventional PCR assays have been commonly used for genetic analysis of EVs. One is the RT-semi-nested PCR assay (VP4-VP2-PCR) that amplifies the VP4-VP2 region for detection of EVs with high sensitivity and the other is the CODEHOP RT-semi-nested PCR assay (CODEHOP PCR) that amplifies the VP1 region for typing. These assays are useful for detection and identification of EVs in many clinical cases. However, we experienced some cases in which we could not identify EV-D68 with CODEHOP PCR from clinical specimens in spite of the results that EV-D68 sequences were detected by VP4-VP2-PCR. In addition, these assays would have trouble in detecting target sequences in those cases where the specimens under examination have been acquired from patients infected with multiple types of EVs. Therefore, we tried to develop a novel RT-semi-nested PCR assay that has high sensitivity and specificity for EV-D68. We designed original primers to be used for the amplification of the VP1 region of EV-D68 and optimized the RT-semi-nested PCR conditions. Sensitivity and specificity were examined with previ-ously accumulated clinical specimens.
{"title":"Optimizing RT-semi-nested PCR Conditions with Newly Developed Primers for the Specific Detection of Human Enterovirus D68 and its Identification from Clinical Specimens","authors":"Yasuo Kaburagi, H. Ueno, A. Kaetsu, K. Tomari, K. Kikuchi, S. Kobori, M. Miyazaki","doi":"10.11150/KANSENSHOGAKUZASSHI.91.376","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.91.376","url":null,"abstract":"Human enterovirus D68 (EV-D68) is a member of the Enterovirus genus (EVs) within the Picornaviridae family, and generally associated with respiratory tract infection. Meanwhile, previous reports suggest that EV-D68 was also associated with acute flaccid paralysis in the clinical cases in USA and Japan. Two conventional PCR assays have been commonly used for genetic analysis of EVs. One is the RT-semi-nested PCR assay (VP4-VP2-PCR) that amplifies the VP4-VP2 region for detection of EVs with high sensitivity and the other is the CODEHOP RT-semi-nested PCR assay (CODEHOP PCR) that amplifies the VP1 region for typing. These assays are useful for detection and identification of EVs in many clinical cases. However, we experienced some cases in which we could not identify EV-D68 with CODEHOP PCR from clinical specimens in spite of the results that EV-D68 sequences were detected by VP4-VP2-PCR. In addition, these assays would have trouble in detecting target sequences in those cases where the specimens under examination have been acquired from patients infected with multiple types of EVs. Therefore, we tried to develop a novel RT-semi-nested PCR assay that has high sensitivity and specificity for EV-D68. We designed original primers to be used for the amplification of the VP1 region of EV-D68 and optimized the RT-semi-nested PCR conditions. Sensitivity and specificity were examined with previ-ously accumulated clinical specimens.","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87249205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-20DOI: 10.11150/KANSENSHOGAKUZASSHI.91.425
Yuko Moriuchi, Maki Furukawa, K. Ohnuma, K. Maniwa
{"title":"A Case of Congenital Toxoplasmosis in an Infant Discovered Through Visual Impairment During a Health Check-up","authors":"Yuko Moriuchi, Maki Furukawa, K. Ohnuma, K. Maniwa","doi":"10.11150/KANSENSHOGAKUZASSHI.91.425","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.91.425","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87053627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-20DOI: 10.11150/KANSENSHOGAKUZASSHI.91.405
H. Kato, Y. Sugiyama, A. Ookawara, Kayoko Sano, H. Nakajima
{"title":"Molecular Epidemiological Analysis of Methicillin-resistant Staphylococcus aureus Isolated from Hospitalized Patients and Outpatients","authors":"H. Kato, Y. Sugiyama, A. Ookawara, Kayoko Sano, H. Nakajima","doi":"10.11150/KANSENSHOGAKUZASSHI.91.405","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.91.405","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89484224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-20DOI: 10.11150/KANSENSHOGAKUZASSHI.91.411
Masaru Tanaka, N. Yanagisawa, K. Fukushima, S. Sasaki, A. Imamura, A. Ajisawa
{"title":"HIV-associated Extracavitary Primary Effusion Lymphoma Successfully Treated with Antiretroviral Agents and CHOP Combination Chemotherapy","authors":"Masaru Tanaka, N. Yanagisawa, K. Fukushima, S. Sasaki, A. Imamura, A. Ajisawa","doi":"10.11150/KANSENSHOGAKUZASSHI.91.411","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.91.411","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86798420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-20DOI: 10.11150/KANSENSHOGAKUZASSHI.91.392
Yuzo Tsuyuki, Takashi Takahashi
It is important to understand the current results concerning isolated bacteria and their antimicrobial susceptibility through urine cultures to perform diagnosis and treatment of urinary tract infections among ill companion animals. However, there are very few investigations regarding the data of urine cultures based on nationwide-surveillance in Japan. The purpose of this study was to determine species identification of the bacteria and their antimicrobial susceptibility through urine cultures obtained from the animals with a nationwide approach. We analyzed the nationwide-surveillance data of bacterial identification and drug susceptibility by standard methods with urine specimens collected from approximate 1,000 animal clinics/ hospitals from 1 st August 2014 to 31 st July 2016 (for two years). Of 6,179 urine samples collected, there were 5,246 bacterial strains isolated from the 3,941 specimens. The most prevalent species identified were Escherichia coli (34.4%)/ Staphylococcus intermedius group (12.9%)/ Enterococcus faecalis (10.2%)/ Klebsiella pneumoniae (6.6%)/ Proteus mirabilis (5.8%)/ Pseudomonas aeruginosa (4.0%)/ Enterococcus faecium (4.0%)/Group G Streptococci (3.2%)/Coagulase-negative Staphylococci (2.2%)/ Enterobacter cloacae (1.7%), indicating that the total proportion was 85.0% of all isolated bacteria. We found that the rate of methicillin-resistant Staphylococci (MRS) was 57.6% among the isolates from the S. intermedius group. We also observed that the detection rates of extended-spectrum β -lactamase (ESBL) were E. coli 42.3%/ K. pneumoniae 63.3%/ P. mirabilis 20.3% among the Enterobacteriaceae isolates from 1 st August 2015 through 31 st July 2016. Carbapenem-resistant strains, multidrug-resistant P . aeruginosa , and vancomycin-resistant strains were not detected. Just as in human infections, the floral bacteria in the rectum were highly isolated from the animalsʼ urine, and the proportions of MRS and ESBL-producing Enterobacteriaceae isolates were high-level. Our observations indicate the current characteristics of antimicrobial resistance among the urine-origin isolates from the animals, suggesting that we should promote antimicrobial stewardships in the animal clinical setting.
{"title":"Isolated Bacteria and Their Antimicrobial Susceptibility through Urine Culture Obtained from Companion Animals in Japan","authors":"Yuzo Tsuyuki, Takashi Takahashi","doi":"10.11150/KANSENSHOGAKUZASSHI.91.392","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.91.392","url":null,"abstract":"It is important to understand the current results concerning isolated bacteria and their antimicrobial susceptibility through urine cultures to perform diagnosis and treatment of urinary tract infections among ill companion animals. However, there are very few investigations regarding the data of urine cultures based on nationwide-surveillance in Japan. The purpose of this study was to determine species identification of the bacteria and their antimicrobial susceptibility through urine cultures obtained from the animals with a nationwide approach. We analyzed the nationwide-surveillance data of bacterial identification and drug susceptibility by standard methods with urine specimens collected from approximate 1,000 animal clinics/ hospitals from 1 st August 2014 to 31 st July 2016 (for two years). Of 6,179 urine samples collected, there were 5,246 bacterial strains isolated from the 3,941 specimens. The most prevalent species identified were Escherichia coli (34.4%)/ Staphylococcus intermedius group (12.9%)/ Enterococcus faecalis (10.2%)/ Klebsiella pneumoniae (6.6%)/ Proteus mirabilis (5.8%)/ Pseudomonas aeruginosa (4.0%)/ Enterococcus faecium (4.0%)/Group G Streptococci (3.2%)/Coagulase-negative Staphylococci (2.2%)/ Enterobacter cloacae (1.7%), indicating that the total proportion was 85.0% of all isolated bacteria. We found that the rate of methicillin-resistant Staphylococci (MRS) was 57.6% among the isolates from the S. intermedius group. We also observed that the detection rates of extended-spectrum β -lactamase (ESBL) were E. coli 42.3%/ K. pneumoniae 63.3%/ P. mirabilis 20.3% among the Enterobacteriaceae isolates from 1 st August 2015 through 31 st July 2016. Carbapenem-resistant strains, multidrug-resistant P . aeruginosa , and vancomycin-resistant strains were not detected. Just as in human infections, the floral bacteria in the rectum were highly isolated from the animalsʼ urine, and the proportions of MRS and ESBL-producing Enterobacteriaceae isolates were high-level. Our observations indicate the current characteristics of antimicrobial resistance among the urine-origin isolates from the animals, suggesting that we should promote antimicrobial stewardships in the animal clinical setting.","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83388924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-20DOI: 10.11150/KANSENSHOGAKUZASSHI.91.387
Y. Takiguchi, Yosuke Suruga, Yoko Akiba, A. Naito, Michio Suzuki, K. Imaoka
{"title":"Capnocytophaga Species Infection：A Report of Ten Cases","authors":"Y. Takiguchi, Yosuke Suruga, Yoko Akiba, A. Naito, Michio Suzuki, K. Imaoka","doi":"10.11150/KANSENSHOGAKUZASSHI.91.387","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.91.387","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90522215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-20DOI: 10.11150/KANSENSHOGAKUZASSHI.91.420
Toshiharu Sasaki, H. Yamashita, A. Mimori
A 78-year-old man presented with fatigue and muscle weakness. His serum creatine kinase level was elevated and an electromyogram showed myogenic conversion. He was diagnosed as having polymyositis. Whole-body computed tomography and an endoscopic study ruled out malignancy. He was prescribed 55mg of prednisolone (1mg/kg/day) and soon thereafter his muscle strength returned to normal. However, while on the steroid, he developed diarrhea. Fecal culture and a Clostridium difficile antigen test were negative. Nonetheless, he was prescribed metronidazole, 1,000mg, twice daily, as empirical therapy for C. difficile infec-tion. His diarrhea progressively worsened, resulting in massive melena, shock, and a fever of 39℃. A subse-quent blood culture was positive for Escherichia coli . He was started on 3g meropenem/day together with fluid and blood transfusions. An upper gastric endoscopy repeated during gastrointestinal bleeding showed diffuse hemorrhagic duodenitis and bleeding erosions. Duodenal biopsy showed strongyloidiasis. After treatment with 12mg ivermectin once every 2 weeks his fecal test remained positive；he was therefore started on a daily dose of ivermectin and albendazole. Despite treatment, he died from gastrointestinal bleeding. The autopsy revealed no evidence of active strongyloidiasis infection. This case demonstrates that, even with successful treatment, the complications of strongyloidiasis, especially gastrointestinal bleeding, can cause death. Thus, in Japan, based on epidemiologic trends, patients who have to undergo strong immuno-suppressive therapy, including large doses of steroids for rheumatic disease, should be screened and prophy-lactically treated for Strongyloides stercoralis
{"title":"A Case of Polymyositis with Severe Gastrointestinal Bleeding Due to Strongyloidiasis","authors":"Toshiharu Sasaki, H. Yamashita, A. Mimori","doi":"10.11150/KANSENSHOGAKUZASSHI.91.420","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.91.420","url":null,"abstract":"A 78-year-old man presented with fatigue and muscle weakness. His serum creatine kinase level was elevated and an electromyogram showed myogenic conversion. He was diagnosed as having polymyositis. Whole-body computed tomography and an endoscopic study ruled out malignancy. He was prescribed 55mg of prednisolone (1mg/kg/day) and soon thereafter his muscle strength returned to normal. However, while on the steroid, he developed diarrhea. Fecal culture and a Clostridium difficile antigen test were negative. Nonetheless, he was prescribed metronidazole, 1,000mg, twice daily, as empirical therapy for C. difficile infec-tion. His diarrhea progressively worsened, resulting in massive melena, shock, and a fever of 39℃. A subse-quent blood culture was positive for Escherichia coli . He was started on 3g meropenem/day together with fluid and blood transfusions. An upper gastric endoscopy repeated during gastrointestinal bleeding showed diffuse hemorrhagic duodenitis and bleeding erosions. Duodenal biopsy showed strongyloidiasis. After treatment with 12mg ivermectin once every 2 weeks his fecal test remained positive；he was therefore started on a daily dose of ivermectin and albendazole. Despite treatment, he died from gastrointestinal bleeding. The autopsy revealed no evidence of active strongyloidiasis infection. This case demonstrates that, even with successful treatment, the complications of strongyloidiasis, especially gastrointestinal bleeding, can cause death. Thus, in Japan, based on epidemiologic trends, patients who have to undergo strong immuno-suppressive therapy, including large doses of steroids for rheumatic disease, should be screened and prophy-lactically treated for Strongyloides stercoralis","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83420700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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