Pub Date : 2018-05-20DOI: 10.11150/kansenshogakuzasshi.92.331
K. Yanagihara, N. Kaku, Hiromichi Suzuki, H. Niimi, H. Mikamo, Tetsuya Matsumoto, K. Tateda
{"title":"Results of a Questionnaire Survey on the Genetic Testing for Infectious Diseases","authors":"K. Yanagihara, N. Kaku, Hiromichi Suzuki, H. Niimi, H. Mikamo, Tetsuya Matsumoto, K. Tateda","doi":"10.11150/kansenshogakuzasshi.92.331","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.92.331","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89503322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-05-01DOI: 10.1542/9781610021470-part03-hepatitis_a
Y. Moritsugu
{"title":"[Hepatitis A].","authors":"Y. Moritsugu","doi":"10.1542/9781610021470-part03-hepatitis_a","DOIUrl":"https://doi.org/10.1542/9781610021470-part03-hepatitis_a","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86675175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-03-20DOI: 10.11150/kansenshogakuzasshi.92.138
Y. Fujikawa, Yoshiaki Gu, Kengo Oshima, Misa Sogi, Chihiro Oe, Noriomi Ishibashi, Hiroaki Baba, S. Inomata, Makiko Yoshida, S. Endo, M. Kaku
{"title":"A Case of Mycotic Aneurysm of the Abdominal Aorta Caused by Aspergillus fumigatus in a Tsunami Survivor After the East Japan Great Earthquake","authors":"Y. Fujikawa, Yoshiaki Gu, Kengo Oshima, Misa Sogi, Chihiro Oe, Noriomi Ishibashi, Hiroaki Baba, S. Inomata, Makiko Yoshida, S. Endo, M. Kaku","doi":"10.11150/kansenshogakuzasshi.92.138","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.92.138","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81132475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-03-20DOI: 10.11150/kansenshogakuzasshi.92.115
Y. Moriyama, K. Iwamoto, M. Katagiri, Reiko Kessoku
{"title":"Causative Bacteria and Proper Antibiotics Selection：a Prospective Investigation of 101 Patients with Cellulitis","authors":"Y. Moriyama, K. Iwamoto, M. Katagiri, Reiko Kessoku","doi":"10.11150/kansenshogakuzasshi.92.115","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.92.115","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85795237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-03-20DOI: 10.11150/kansenshogakuzasshi.92.120
Yuki Sato, M. Shinagawa, Yusuke Takahashi, Masachika Saeki, Yuki Yakuwa, S. Takahashi
We have evaluated the performance among four brands of immunochromatography (IC) assay kits, available in the market in Japan, for detection of norovirus antigen and compared with Real Time PCR (RT-PCR) assays. The four brands used were ImmunoCatch-Noro (A Kit, EIKEN CHEMICAL Co., Ltd., Japan), Quick Chaser-Noro (B Kit, MIZUHO MEDY Co., Ltd., Saga, Japan), GE test Noro Nissui (C Kit, NISSUI PHARMACEUTICAL Co., Ltd., Tokyo, Japan), and Quick Navi-Noro2 (D Kit, DENKA SEIKEN Co., Ltd., Tokyo, Japan). The results from the RT-PCR analysis of 69 suspected cases of norovirus infection identified 6 cases of Genogroup I (GI) and 22 cases of Genogroup II (GII) infection, whereas one case among them had a mixed infection of both GI and GII. The virus titers of the positive samples varied from 1.54×10 1 to 3.14× 10 8 copies/ μ L. The genotypes identified were as follows：GI, GI.1 (1 case each), GI.2 (3 cases), and GI.3 (2 cases)；GII, GII.2 (1 case each), GII.4 (7 cases), GII.13 (2 cases), and GII.17 (12 cases). The positive concordance rates between the IC assay kits and the Real Time RT-PCR were as follows：A, 59.3 % ；B, 51.9 % ；C, 51.9 % ；and
我们评估了日本市场上四种品牌的免疫层析(IC)检测试剂盒检测诺如病毒抗原的性能，并与实时PCR (RT-PCR)检测方法进行了比较。使用的四个品牌分别是immunocapture -Noro (A试剂盒，EIKEN CHEMICAL Co.， Ltd.，日本)、Quick Chaser-Noro (B试剂盒，MIZUHO medicine Co.， Ltd.， Saga，日本)、GE test Noro Nissui (C试剂盒，Nissui PHARMACEUTICAL Co.， Ltd.，日本东京)和Quick Navi-Noro2 (D试剂盒，DENKA SEIKEN Co.， Ltd.，日本东京)。对69例诺如病毒疑似感染病例进行RT-PCR分析，鉴定为基因I型(GI)感染6例，基因II型(GII)感染22例，其中1例为GI和GII混合感染。阳性标本的病毒滴度为1.54×10 1 ~ 3.14× 10 8拷贝/ μ l，鉴定的基因型为GI、GI.1(各1例)、GI.2(3例)和GI.3(2例);GII、GII.2(各1例)、GII.4(7例)、GII.13(2例)和GII.17(12例)。IC试剂盒与Real Time RT-PCR的阳性符合率分别为:A, 59.3%;B, 51.9%;C, 51.9%
{"title":"Evaluation of Performance Among Norovirus Antigen Detection Kits with Immunochromatography","authors":"Yuki Sato, M. Shinagawa, Yusuke Takahashi, Masachika Saeki, Yuki Yakuwa, S. Takahashi","doi":"10.11150/kansenshogakuzasshi.92.120","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.92.120","url":null,"abstract":"We have evaluated the performance among four brands of immunochromatography (IC) assay kits, available in the market in Japan, for detection of norovirus antigen and compared with Real Time PCR (RT-PCR) assays. The four brands used were ImmunoCatch-Noro (A Kit, EIKEN CHEMICAL Co., Ltd., Japan), Quick Chaser-Noro (B Kit, MIZUHO MEDY Co., Ltd., Saga, Japan), GE test Noro Nissui (C Kit, NISSUI PHARMACEUTICAL Co., Ltd., Tokyo, Japan), and Quick Navi-Noro2 (D Kit, DENKA SEIKEN Co., Ltd., Tokyo, Japan). The results from the RT-PCR analysis of 69 suspected cases of norovirus infection identified 6 cases of Genogroup I (GI) and 22 cases of Genogroup II (GII) infection, whereas one case among them had a mixed infection of both GI and GII. The virus titers of the positive samples varied from 1.54×10 1 to 3.14× 10 8 copies/ μ L. The genotypes identified were as follows：GI, GI.1 (1 case each), GI.2 (3 cases), and GI.3 (2 cases)；GII, GII.2 (1 case each), GII.4 (7 cases), GII.13 (2 cases), and GII.17 (12 cases). The positive concordance rates between the IC assay kits and the Real Time RT-PCR were as follows：A, 59.3 % ；B, 51.9 % ；C, 51.9 % ；and","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78835700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-03-20DOI: 10.11150/kansenshogakuzasshi.92.103
H. Ikematsu, Nobuyuki Yamashita, M. Ogawa, Motonori Hirano, Martina Kovac, D. Watanabe
Two large randomized multinational efficacy trials (ZOE-50 and ZOE-70) showed that the novel herpes zoster subunit vaccine (HZ/su) candidate containing varicella-zoster virus glycoprotein E (gE) and the AS01 B adjuvant system reduced the risk of herpes zoster (HZ) and post-herpetic neuralgia (PHN) by more than 90%. We conducted a descriptive subgroup analysis in subjects enrolled in Japan in these studies and evalu-ated the results.
{"title":"Efficacy, Safety and Immunogenicity of a Novel Adjuvanted Subunit Herpes Zoster Vaccine in Japanese Aged 50 Years and 70 Years and Older","authors":"H. Ikematsu, Nobuyuki Yamashita, M. Ogawa, Motonori Hirano, Martina Kovac, D. Watanabe","doi":"10.11150/kansenshogakuzasshi.92.103","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.92.103","url":null,"abstract":"Two large randomized multinational efficacy trials (ZOE-50 and ZOE-70) showed that the novel herpes zoster subunit vaccine (HZ/su) candidate containing varicella-zoster virus glycoprotein E (gE) and the AS01 B adjuvant system reduced the risk of herpes zoster (HZ) and post-herpetic neuralgia (PHN) by more than 90%. We conducted a descriptive subgroup analysis in subjects enrolled in Japan in these studies and evalu-ated the results.","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73149962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-03-20DOI: 10.11150/kansenshogakuzasshi.92.126
I. Nakagiri, H. Wada, H. Tokunaga, T. Tasaka, T. Sugihara
We evaluated a new immunochromatographic assay (ICA) for the detection of hepatitis B surface antigen (HBsAg) (Alere HBsAg；Alere Medical Co., Ltd) using 275 serum and 40 whole blood (EDTA) samples screened in our hospital. Five seroconversion panels and a reference panel according to the WHO International Standard for HBsAg were also tested. The performance of the ICA was compared with that of the conventional ICA (ICA2), chemiluminescent enzyme immunoassay (qualitative CLEIA), and chemiluminescent assay (quantitative CLIA). The sensitivity of the ICA in 54 HBV DNA positive specimens with a RT-PCR (TaqMan assay) was 98.1% (53/54), better than the ICA2 -92.6%- (50/54) and the CLEIA -96.3%- (52/54), and equivalent to the CLIA -98.1%- (53/54). The specificity in 221 HBV DNA negative specimens was 100%, better than the ICA2 -99.5%- (220/221), and equivalent to the CLEIA and CLIA. The ICA indicated a de-tectability superior to the ICA2 and CLEIA, and equivalent to the CLIA in the seroconversion panels. The limit of detection of the assay was calculated as 0.1IU/mL based on the results of the CLIA assay with the seroconversion panels. This assay using an avidin-biotin format demonstrated to show an excellent sensitivity and specificity in the clinical specimens and the panels. We conclude that this simple and rapid assay with a capability for whole blood sample application is suitable and applicable for use in risk management in patients with resolved HBV infection as well as in emergency and resource-limited settings.
{"title":"Evaluation of a Newly Developed Immunochromatographic Assay, for the Detection of HBsAg with Sensitivity and Specificity Equivalent to Those of Chemiluminescent Immunoassays","authors":"I. Nakagiri, H. Wada, H. Tokunaga, T. Tasaka, T. Sugihara","doi":"10.11150/kansenshogakuzasshi.92.126","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.92.126","url":null,"abstract":"We evaluated a new immunochromatographic assay (ICA) for the detection of hepatitis B surface antigen (HBsAg) (Alere HBsAg；Alere Medical Co., Ltd) using 275 serum and 40 whole blood (EDTA) samples screened in our hospital. Five seroconversion panels and a reference panel according to the WHO International Standard for HBsAg were also tested. The performance of the ICA was compared with that of the conventional ICA (ICA2), chemiluminescent enzyme immunoassay (qualitative CLEIA), and chemiluminescent assay (quantitative CLIA). The sensitivity of the ICA in 54 HBV DNA positive specimens with a RT-PCR (TaqMan assay) was 98.1% (53/54), better than the ICA2 -92.6%- (50/54) and the CLEIA -96.3%- (52/54), and equivalent to the CLIA -98.1%- (53/54). The specificity in 221 HBV DNA negative specimens was 100%, better than the ICA2 -99.5%- (220/221), and equivalent to the CLEIA and CLIA. The ICA indicated a de-tectability superior to the ICA2 and CLEIA, and equivalent to the CLIA in the seroconversion panels. The limit of detection of the assay was calculated as 0.1IU/mL based on the results of the CLIA assay with the seroconversion panels. This assay using an avidin-biotin format demonstrated to show an excellent sensitivity and specificity in the clinical specimens and the panels. We conclude that this simple and rapid assay with a capability for whole blood sample application is suitable and applicable for use in risk management in patients with resolved HBV infection as well as in emergency and resource-limited settings.","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74181145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-03-20DOI: 10.11150/kansenshogakuzasshi.92.133
Hisaaki Nishio, Kohsuke Asagoe
{"title":"A Case of Helicobacter cinaedi Isolated from Inflammatory Intestinal Mucosa Following Bacteremia with Diffuse Large B-cell Lymphoma","authors":"Hisaaki Nishio, Kohsuke Asagoe","doi":"10.11150/kansenshogakuzasshi.92.133","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.92.133","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85405633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-03-20DOI: 10.11150/KANSENSHOGAKUZASSHI.92.144
卓 小笠原, 岡部 敏明, 成田 光生, 大島 美保, 村田 亮
{"title":"非流行地（北海道）で経験したレプトスピラ症の1例","authors":"卓 小笠原, 岡部 敏明, 成田 光生, 大島 美保, 村田 亮","doi":"10.11150/KANSENSHOGAKUZASSHI.92.144","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.92.144","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82727107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-20DOI: 10.11150/kansenshogakuzasshi.92.51
A. Watanabe, S. Kashiwagi, H. Ikematsu, H. Yamaguchi, S. Seki, Kazuhito Shiosakai
{"title":"Safety and Prophylactic Efficacy Against Influenza of Laninamivir Octanoate Hydrate,A Long-acting Neuraminidase Inhibitor, in High-risk Patients Including the Elderly","authors":"A. Watanabe, S. Kashiwagi, H. Ikematsu, H. Yamaguchi, S. Seki, Kazuhito Shiosakai","doi":"10.11150/kansenshogakuzasshi.92.51","DOIUrl":"https://doi.org/10.11150/kansenshogakuzasshi.92.51","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81628709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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