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A Case of Invasive Pneumococcal Disease Caused by Non-vaccine Serotype Streptococcus pneumoniae 非疫苗血清型肺炎链球菌所致侵袭性肺炎球菌病1例
Pub Date : 2019-11-20 DOI: 10.11150/kansenshogakuzasshi.93.763
Sachie Koyama, Noriyuki Watanabe, Junpei Matsuno, Mayu Tabira, G. Hashikita, Yoshitada Taji, Kiyoko Kobayashi, J. Sakai, N. Tarumoto, H. Kurita, K. Mitsutake, Yasuhiro Ebihara
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引用次数: 0
A Case of HIV Infection Who Had Enterocolitis and Biliary Disease Due to Cyclospora after Traveling to India 印度旅行后感染HIV并发肠结肠炎及胆道疾病1例
Pub Date : 2018-05-20 DOI: 10.11150/kansenshogakuzasshi.92.371
R. Sekiya, K. Fukushima, Masaru Tanaka, K. Yajima, K. Yagita, A. Ajisawa, A. Imamura
A 48-year-old HIV-positive female had discontinued her hospital visits for about 1.5 years. Immediately after returning from a 1.5-month stay in India, she suffered from diarrhea about four times a day and, there-fore, visited our outpatient department. Liver dysfunction was noted on blood sampling, and bileduct dilatation was detected by magnetic resonance imaging (MRI).Using feces, duodenum, and large intestine specimens, neon blue autofluorescence of the oocyst wall was detected under UV excitation with a fluorescence microscope. These specimens were molecularly biologically identified as Cyclospora cayetanensis using PCR sequencing. Since approval could not be obtained for the treatment of Cyclospora , only antiretroviral therapy (ART) was resumed. The CD4-positivity was above 180/ μ L for about 4 months, but alkaline phosphatase be-came exacerbated. Subsequently, the treatment of Cyclospora was started by prescribing trimethoprim/sul-famethoxazole (ST) (80/160mg, 4 tablets) for 10 days. The liver dysfunction and diarrhea were promptly alle-viated, and the bileduct dilatation was improved on MRI. In study, biliary disease and enteritis due Cyclospora effectively treated with an ST formulation. C. tract in HIV-infected cases in
一名48岁的艾滋病毒阳性女性已停止住院约1.5年。在印度呆了1.5个月回来后,她立即出现腹泻,每天大约四次,因此来到我们的门诊部。血液检查发现肝功能不全,核磁共振(MRI)检查胆管扩张。取粪便、十二指肠和大肠标本,用荧光显微镜在紫外激发下检测卵囊壁的霓虹蓝色自身荧光。这些标本经分子生物学鉴定为卡耶坦环孢子虫。由于无法获得治疗环孢子虫的批准,只能恢复抗逆转录病毒治疗(ART)。cd4阳性维持在180/ μ L以上约4个月,但碱性磷酸酶逐渐加重。随后给予甲氧苄啶/磺胺甲恶唑(ST) (80/160mg, 4片)治疗,疗程10 d。肝功能障碍和腹泻迅速缓解,胆管扩张在MRI上得到改善。在研究中,ST制剂可有效治疗由环孢子虫引起的胆道疾病和肠炎。C.生殖道在艾滋病毒感染病例中
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引用次数: 0
The Influence of a Legal Revision on Infectious Agent Surveillance in Local Public Health Institutes 法律修订对地方公共卫生机构传染病监测的影响
Pub Date : 2018-05-20 DOI: 10.11150/kansenshogakuzasshi.92.365
Fumiya Yamada, K. Uchida, M. Shinohara, Tsuyoshi Kisimoto
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引用次数: 0
A Serological Survey of Yersinia pseudotuberculosis Infection (1999―2016) 1999-2016年假结核耶尔森菌感染血清学调查
Pub Date : 2018-05-20 DOI: 10.11150/kansenshogakuzasshi.92.353
H. Nakajima, Hideaki Kariya, T. Kishimoto
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引用次数: 1
Murine Typhus which was Difficult to Distinguish from Typhoid Fever;a Case Report and an Effective Collaboration with a Local Institute of Public Health 难以与伤寒区分的鼠斑疹伤寒一例报告及与当地公共卫生研究所的有效合作
Pub Date : 2018-05-20 DOI: 10.11150/kansenshogakuzasshi.92.391
Tomohiro Hosoda, Takako Misaki, H. Shimizu, N. Okabe, M. Sakamoto
Herein we present the case of a 19-year-old healthy Filipino woman with a 4-day history of fever and headache, who upon admission had a dry cough and rashes distributed on her trunk and proximal limbs. The patient had recently traveled to the Philippines, 1-4 weeks prior to admission, where she had been in close contact with cats and rodents. Laboratory tests showed thrombocytopenia, and elevation of liver en-zyme and C-reactive protein levels. Subsequent polymerase chain reaction (PCR) tests for D e n g u e , Chik un g un ya , and Zika virus, respectively, and Giemsa-stained blood smear for malaria were negative. Her chest X-ray was normal. Our initial diagnosis was typhoid fever. However, even after administering ceftriaxone, the patientʼs fever and headache remained unimproved. A PCR analysis for Rickettsia species was then performed on day 6 of hospitalization, which revealed the presence of Rickettsia typhi . Therefore, the patient was diagnosed as having murine typhus, and minocycline treatment was started on day 9 of hospitalization. The patientʼs clinical symptoms then continued to improve until discharge on day 11 of hospitalization. Diag-nosing murine typhus is difficult in clinical practice because of the non-specific symptoms. Respiratory symptoms and rashes spreading to the extremities will be indicators in distinguishing murine typhus from typhoid fever.
本文报告一名19岁健康菲律宾女性,有发热和头痛4天的病史,入院时出现干咳和躯干和近端肢体出现皮疹。患者在入院前1-4周曾前往菲律宾,在那里曾与猫和啮齿动物密切接触。实验室检查显示血小板减少,肝酶和c反应蛋白水平升高。随后分别对埃博拉病毒、寨卡病毒和寨卡病毒进行聚合酶链反应(PCR)检测,以及对疟疾进行吉姆萨染色血涂片检测均为阴性。她的胸部x光片正常。我们最初的诊断是伤寒。然而,即使在给予头孢曲松后,患者的发烧和头痛仍然没有改善。然后在住院第6天对立克次体进行PCR分析,结果显示存在伤寒立克次体。因此,患者被诊断为鼠斑疹伤寒,住院第9天开始使用米诺环素治疗。患者的临床症状持续改善,直到住院第11天出院。由于鼠斑疹伤寒的症状不具有特异性,在临床中诊断困难。呼吸道症状和蔓延至四肢的皮疹将是区分鼠斑疹伤寒的指标。
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引用次数: 0
The Analysis of Invasive Haemophilus influenza Infections During the Past Thirteen Years 过去十三年侵袭性流感嗜血杆菌感染分析
Pub Date : 2018-05-20 DOI: 10.11150/kansenshogakuzasshi.92.347
H. Shimizu, Saori Kida, Y. Sugiyama, Soichiro Sugiyama, Y. Matsumoto, Y. Ota, J. Tsukiji, E. Miyajima, S. Ito
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引用次数: 0
Cerebral Syphilitic Gumma Suspected to have Developed during Primary Syphilis and Treated with Antibiotics in an HIV-Negative Patient 1例hiv阴性患者怀疑在原发性梅毒期间发生的脑性梅毒牙龈,并给予抗生素治疗
Pub Date : 2018-05-20 DOI: 10.11150/kansenshogakuzasshi.92.386
N. Tsuda, Tadanao Harigae, Y. Masui, Y. Kikuchi, M. Mizokami, H. Yazaki
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引用次数: 0
梅毒に対するアモキシシリン1,500mg 内服治療の臨床的効果 口服1500毫克阿莫西林治疗梅毒的临床效果
Pub Date : 2018-05-20 DOI: 10.11150/KANSENSHOGAKUZASSHI.92.358
和彦 池内, 一彰 福島, 勝 田中, 矢嶋 敬史郎, 紀貴 関谷, 綾子 関谷, 如樹 柳澤, 篤 味澤, 顕史 今村
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引用次数: 0
A Case of Necrotising Soft-tissue Infection and Sepsis Caused by Shewanella haliotis 雪瓦氏菌性结肠炎致软组织坏死性感染及败血症1例
Pub Date : 2018-05-20 DOI: 10.11150/kansenshogakuzasshi.92.380
H. Kimura, K. Mizutomi, Eiichi Ohta, Akiko Nakano, K. Ohkusu
Shewanella haliotis is an aquatic gram-negative rod, recently isolated from the gut microflora of abalone ( Haliotis discus hannai ) in 2007. Human disease caused by this species is extremely rare. We report the case of a 66-year-old man undergoing hemodialysis who was admitted for necrotizing soft-tissue infection on the left hand with sepsis. He had a history of liver cirrhosis and colon cancer. Clinical findings showed swollen erythema with purpura and bullae on his left hand. Gram-negative rods were detected in the blood culture. The colonies grew on the Thiosulfate Citrate Bile Salts Sucrose medium (TCBS), and produced H 2 S on the Triple Sugar Iron (TSI) agar. The pathological features presented hemorrhagic necrosis with an infiltration of neutrophils and lymphocytes in the subcutaneous tissue. S. haliotis was identified by 16S rRNA sequence analysis, nevertheless automated identification in the hospital showed Shewanella algae . Ceftazidime and isepamicin administration for 1 week and cefozopran and isepamicin administration for 1 week followed by oral levofloxacin for 1 week cured the sepsis, and furthermore, topical ointment completely cured the skin ulcer over 2.5 months. We should be aware that human infection caused by S. haliotis can result in severe necrotising soft-tissue infection with sepsis.
雪瓦氏菌是一种水生革兰氏阴性杆状菌,最近于2007年从鲍鱼的肠道菌群中分离出来。由该物种引起的人类疾病极为罕见。我们报告的情况下,66岁的男子接受血液透析谁是入院坏死性软组织感染的左手败血症。他有肝硬化和结肠癌的病史。临床表现为左手有红肿红斑、紫癜及大疱。血培养检出革兰氏阴性棒。菌落在硫代硫酸柠檬酸胆盐蔗糖培养基(TCBS)上生长,在三糖铁(TSI)琼脂上产生h2s。病理表现为出血性坏死,皮下组织中性粒细胞和淋巴细胞浸润。haliotis通过16S rRNA序列分析鉴定,但医院的自动鉴定显示为希瓦氏菌藻类。头孢他啶联合isepamin治疗1周,头孢opran联合isepamin治疗1周后再口服左氧氟沙星治疗1周,局部软膏治疗2.5个月后皮肤溃疡完全治愈。我们应该意识到,由链球菌引起的人类感染可导致严重的坏死性软组织感染和败血症。
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引用次数: 0
An Infected Bulla Caused by Nocardia nova 诺卡菌引起的球囊感染
Pub Date : 2018-05-20 DOI: 10.11150/kansenshogakuzasshi.92.376
K. Isomoto, H. Yamakawa, E. Hagiwara, Masahiro Hayashi, R. Shintani, T. Katano, T. Ogura
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引用次数: 0
期刊
Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases
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