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2022 14th Biomedical Engineering International Conference (BMEiCON)最新文献

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Automatic Ray-Sum Panoramic Synthesis from Cone-Beam CT Data 从锥束CT数据自动射线和全景合成
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10011585
Duangkamol Banarsarn, W. Narkbuakaew, Kongyot Wangkaoom, Saowanee Iamsiri, S. Thongvigitmanee
A panoramic image can be reconstructed from a cone-beam CT (CBCT) dataset to manifest anatomical structures of all teeth in a patient’s mouth in one image. This research proposed a new automatic method to synthesize a ray-sum panoramic image from a dental CBCT dataset. The objective of the proposed method was to create the curve segment over the whole dental arch to instantly generate a ray-sum panoramic image. We applied the proposed algorithm to eighteen datasets, and all processes were computed under the web browser’s environment. From the results, the curve segments were consistently generated for all datasets. The edges of anatomical structures in the panoramic image were enhanced. On average, the computational time was under 5 seconds to compute the large volumetric data sized 500x500x450 voxels. In conclusion, the proposed method was functional for the web application. A raysum panoramic was quickly synthesized, and anatomical structures were clearly displayed in a web browser.
锥形束CT (cone-beam CT, CBCT)数据集可以重构出一幅全景图像,从而在一张图像中显示患者口腔中所有牙齿的解剖结构。提出了一种自动合成牙齿CBCT数据集射线和全景图像的新方法。该方法的目标是在整个牙弓上创建曲线段,以立即生成射线和全景图像。我们将该算法应用于18个数据集,并在web浏览器环境下对所有过程进行了计算。从结果来看,所有数据集都一致地生成了曲线段。增强了全景图像中解剖结构的边缘。平均而言,计算500x500x450体素的大型体积数据所需的计算时间不到5秒。总之,所提出的方法对web应用程序是有效的。快速合成了射线全景图,并在web浏览器中清晰地显示了解剖结构。
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引用次数: 0
A Low-Cost Digital Stethoscope For Normal and Abnormal Heart Sound Classification 一种低成本数字听诊器用于心音正常与异常分类
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012113
Sorawit Khoruamkid, S. Visitsattapongse
Heart disease is a major problem in most deaths. To conquer this situation, heartbeat sound analysis is a convenient method for diagnosing heart disease. Heartbeat sound classification remains a challenging problem in heart sound division and feature extraction. A stethoscope is a medical device widely used by physicians to listen to the heartbeat. An acoustic stethoscope operates on the chest piece to the ears of the listener. The main problem is in listening to heart sounds that the low signal level and are difficult to be analyzed. Adding electronic circuitry and software to acoustic stethoscopes will strengthen the heart rate signal and can minimize error analysis of the state of the patient's heart. Machine learning is used to efficiently analyze and classify heart sounds. Convolutional Neural Network (CNN) models and Support Vector Machine (SVM) with feature extractors were effective methods and were used in this research. First, the Phonocardiogram (PCG) files are fragmented into pieces of equivalent length. Then, we convert the PCG files to a spectrogram. The spectrogram images are fed into a convolutional neural network and support vector machine. The best result is using an Inception V3 model with the CNN classifier which has an accuracy of 0.909, with 0.948 sensitivity and 0.869 specificity.
心脏病是大多数人死亡的主要原因。为了克服这种情况,心跳声分析是一种方便的心脏病诊断方法。心音分类是心音划分和特征提取的难点。听诊器是一种被医生广泛用于听心跳的医疗设备。听诊器在听诊者的胸部和耳朵上工作。主要问题是在听心音时信号电平低,难以分析。在声学听诊器上添加电子电路和软件将增强心率信号,并可以最大限度地减少对患者心脏状态的错误分析。机器学习被用来有效地分析和分类心音。卷积神经网络(CNN)模型和带特征提取器的支持向量机(SVM)是研究中使用的有效方法。首先,心音图(PCG)文件被分割成等长的片段。然后,我们将PCG文件转换为频谱图。频谱图图像被送入卷积神经网络和支持向量机。最好的结果是使用Inception V3模型和CNN分类器,准确率为0.909,灵敏度为0.948,特异性为0.869。
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引用次数: 0
Development of Variable-Elasticity Cell Scaffolds Using Magnetic Gels 磁性凝胶制备变弹性细胞支架
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012083
Yuya Shimomura, Zugui Peng, K. Shimba, Y. Miyamoto, T. Yagi
It is well known that cells are influenced by the properties of their extracellular matrix, which is primarily composed of sugars and proteins. In particular, there exists a strong relationship between the elasticity of the extracellular substrate and cell motility. Clarification of the relationship between cells and substrate elasticity is expected to prove useful in both the design of scaffold materials for tissue engineering and the elucidation of the mechanisms of diseases that cause fibrosis. The elasticity of the extracellular matrix is characterized by two features: a partial elastic gradient and day-to-day variation. Most previous studies reproduced either one or the other, and this likely does not reflect the in vivo situation. Thus, a greater understanding of the changes in cells and substrates is needed. In this study, we propose a scaffold based on a magnetic gel with variable elasticity. We describe the preparation of a magnetic gel and cell seeding on its surface. The cells were cultured under the application of magnetic force after seeding, revealing an increase in the cell area due to the hardening of the magnetic gel in the presence of magnetic force.
众所周知,细胞受其细胞外基质特性的影响,细胞外基质主要由糖和蛋白质组成。特别是,在细胞外基质的弹性和细胞运动之间存在着很强的关系。澄清细胞和底物弹性之间的关系有望在组织工程支架材料的设计和引起纤维化的疾病机制的阐明中证明是有用的。细胞外基质的弹性具有两个特征:部分弹性梯度和逐日变化。大多数先前的研究都再现了其中一种或另一种,这可能不能反映体内的情况。因此,需要对细胞和底物的变化有更深入的了解。在这项研究中,我们提出了一种基于可变弹性磁凝胶的支架。我们描述了磁性凝胶的制备和细胞在其表面的播种。细胞播种后在磁力作用下培养,发现由于磁性凝胶在磁力作用下硬化,细胞面积增加。
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引用次数: 0
Preliminary Study of the Relationship Between Age and Gender using Sounds Generated from the Nostrils and Pharynx During Swallowing in Healthy Subjects 利用健康受试者吞咽时鼻腔和咽部发出的声音初步研究年龄和性别的关系
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012075
Naru Sato, T. Igasaki, Chiharu Matsumoto, Tadashi Sakata, Hitomi Maeda
Although many studies have evaluated swallowing using sounds from the pharynx, few studies have evaluated it using sounds from the nostrils. Therefore, in this study, we placed two microphones near the nostrils and pharynx and recorded sounds produced while swallowing five grams of solid jelly. The participants included 16 healthy volunteers (eight in their early twenties (22-24 years old; younger group) and eight early elderly (66-74 years old; elder group), four males and four females in each group) over eight trials. We then examined the peak sound pressure levels of the nostrils and pharynx waveforms and investigated the time lags between the sounds generated by the nostrils and pharynx in each subject. As a result, although the time lags varied across the subjects, the minimum time lags observed in the elder group (0.32 – 0.78 s) were significantly longer than those of the younger group (0.04 – 0.44 s. $F_{1:15}$ = 30.10, $p lt 0.05$, repeated two-way ANOVA), and the maximum time lags observed in the female subjects were significantly longer (1.04 – 2.30 s) than those of males (0.20 – 1.43 s. $F_{1:15}$ = 5.57, $p lt 0.05$, repeated two-way ANOVA). It was suggested that measuring the sounds from both the pharynx and nostrils during swallowing helps in evaluating the swallowing function with aging, and considering gender differences.
尽管许多研究已经评估了使用咽部发出的声音来吞咽,但很少有研究评估了使用鼻孔发出的声音。因此,在这项研究中,我们在鼻孔和咽附近放置了两个麦克风,记录了吞咽5克固体果冻时产生的声音。参与者包括16名健康志愿者(8名20岁出头(22-24岁;年轻组)和8名早期老年人(66-74岁;老年人组(每组四男四女)进行了八次试验。然后,我们检查了鼻孔和咽部波形的峰值声压级,并研究了每个受试者鼻孔和咽部产生的声音之间的时间滞后。结果表明,虽然被试之间的时间滞后存在差异,但老年组的最小时间滞后(0.32 ~ 0.78 s)显著长于年轻组(0.04 ~ 0.44 s, $F_{1:15}$ = 30.10, $p lt 0.05$,重复双向方差分析),女性被试的最大时间滞后(1.04 ~ 2.30 s)显著长于男性(0.20 ~ 1.43 s, $F_{1:15}$ = 5.57, $p lt 0.05$,重复双向方差分析)。研究表明,在考虑性别差异的情况下,同时测量吞咽过程中咽部和鼻孔发出的声音有助于评估随年龄增长的吞咽功能。
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引用次数: 0
The Importance of Gender Specification for Detection of Driver Fatigue using a Single EEG Channel 性别特征对单脑电通道驾驶员疲劳检测的重要性
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012118
M. Shahbakhti, Matin Beiramvand, Erfan Nasiri, W. Chen, Jordi Solé-Casals, M. Wierzchoń, Anna Broniec-Wójcik, P. Augustyniak, V. Marozas
Although detection of the driver fatigue using a single electroencephalography (EEG) channel has been addressed in literature, the gender differentiation for applicability of the model has not been investigated heretofore. Motivated accordingly, we address the detection of driver fatigue based the gender-segregated datasets, where each of them contains 8 subjects. After splitting the EEG signal into its sub-bands (delta, theta, alpha, beta, and gamma) using discrete wavelet transform, the log energy entropy of each band is computed to form the feature vector. Afterwards, the feature vector is randomly split into 50% for training and 50% for the unseen testing, and fed to a support vector machine model. When comparing the classification results of fatigue driving detection between the gender segregated and non-gender segregated datasets, the former achieved the accuracy 78% and 77% for male and female subjects, respectively, than the latter (71%). The obtained results show the importance of gender-specification for the driver fatigue detection.
尽管使用单一脑电图(EEG)通道检测驾驶员疲劳已在文献中得到解决,但迄今为止尚未研究该模型适用性的性别分化。因此,我们基于性别隔离的数据集解决驾驶员疲劳检测问题,其中每个数据集包含8个受试者。利用离散小波变换将脑电信号分成delta、theta、alpha、beta和gamma四个子波段,计算每个波段的对数能量熵,形成特征向量。然后,将特征向量随机分成50%用于训练和50%用于未见测试,并将其馈送到支持向量机模型中。对比性别隔离和非性别隔离数据集的疲劳驾驶检测分类结果,前者对男性和女性受试者的准确率分别为78%和77%,后者为71%。研究结果表明,性别规范对驾驶员疲劳检测具有重要意义。
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引用次数: 2
Computerized Medical Device Management System In Luangprabang Provincial Hospital 琅勃拉邦省医院计算机化医疗设备管理系统
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012115
Sengaloun Xayalath, N. Thongpance, Anantasak Wongkamhang, Anuchit Nirapai
This research aims to design and develop a Computerized Medical Device Maintenance Management System (CMDMS) for managing medical device systems of Luangprabang Provincial hospital, Lao People’s Democratic Republic. The process of designing and developing such CMDMS consists of 3 main components: 1) the structure design of the system using Visual Studio, 2) programming in PHP and 3) Creating a database and a recording system using My SQL. The results showed that it is designed to meet the specific needs of Luangprabang Provincial hospital, Lao People’s Democratic Republic. The CMDMS can actually be used in the medical device management system of the hospital, solve problems and facilitate, as well as reduce procedures and speed up the management of medical devices, as well as save budgets for the organization in accordance with the objectives of the design and construction and follows the Generic Clinical Engineering Maintenance Management System suggested by Association for the Advancement of Medical Instrumentation (AAMI).
本研究旨在设计并开发一个计算机化医疗器械维护管理系统(CMDMS),用于管理老挝人民民主共和国琅勃拉邦省医院的医疗器械系统。该CMDMS的设计和开发过程主要包括3个部分:1)使用Visual Studio进行系统的结构设计,2)使用PHP进行编程,3)使用My SQL创建数据库和记录系统。结果表明,该方案旨在满足老挝人民民主共和国琅勃拉邦省医院的具体需要。CMDMS可以实际应用于医院的医疗器械管理系统,解决问题,方便,减少程序,加快医疗器械的管理,为组织节省预算,按照设计和建设的目标,遵循美国医疗器械促进会(AAMI)建议的通用临床工程维护管理系统。
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引用次数: 0
The effect of visual cognition on the fear caused by pain recall 视觉认知对疼痛回忆引起的恐惧的影响
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012108
Nina Itagaki, K. Iramina, Yutarou Nakada
In this study, we investigated ‘pain recall’ that results from showing a painful image and evoking pain without actually giving any pain, that is said to be similar to the brain activity that actually causes pain. The experiment involved 12 students showing three short videos in which a child, a female, or a male was being injected. We measured the degree of emotional changes by watching the painful scene in three ways: emotion estimation by facial expression, GSR (Galvanic Skin Response) and Eye tracking. The results showed that subjects felt the same fear and tension as when feeling pain. On the other hand, subjects felt less painful emotions when they looked at the scene that a man with solid arms was injected. The degree of emotion in pain recall varied depending on who received the injection in the short videos. These results suggest that pain may be reduced by showing some body images as visual information. It is possible to alleviate actual pain by applying how to reduce ‘pain recall’.
在这项研究中,我们调查了“疼痛回忆”,即显示疼痛图像并在没有实际产生疼痛的情况下唤起疼痛,据说这与实际引起疼痛的大脑活动相似。在这项实验中,12名学生播放了三段短视频,视频中有一名儿童、一名女性和一名男性正在接受注射。我们通过观看痛苦场景来测量情绪变化的程度,这三种方法分别是:面部表情情绪估计、皮肤电反应(GSR)和眼动追踪。结果显示,受试者在感到疼痛时也会感到同样的恐惧和紧张。另一方面,当受试者看到一个手臂结实的人被注射的场景时,他们感受到的痛苦情绪就会减少。回忆疼痛时的情绪程度取决于在短视频中接受注射的人。这些结果表明,通过展示一些身体图像作为视觉信息,疼痛可能会减少。通过应用如何减少“疼痛回忆”,有可能减轻实际的疼痛。
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引用次数: 0
Evaluating Improvement on Feature Selection for Classification of Implicit Learning on EEG’s Multiscale Entropy Data using BMNABC 基于BMNABC的脑电多尺度熵数据内隐学习分类特征选择改进评价
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012069
Chayapol Chaiyanan, B. Kaewkamnerdpong
Those who are good at implicit learning can learn things faster and are more adaptable in the fast pace age of information. Implicit learning is a type of learning without being explicitly taught. It’s commonly seen in younger children when they develop their ability to speak their native language without learning grammar. The human brain can be trained to be good at learning by training the brain to be in the state of learning more often. By using neurofeedback to regulate the human brain state, educators and learners can help each other in training the brain to be better implicit learners. Our research aims to classify implicit learning events from EEG signals to help identify and moderate such states. This paper analyzed the feature selection process section to improve classification performance. We used previously measured participants' EEG signals while performing cognitive task experiments. Those signals were then getting feature extracted into Multiscale Entropy. Previously, Artificial Bee Colony (ABC) was used on the Multiscale Entropy to help classify the implicit learning events with reasonable success. However, an improvement was required to make the entire system more optimized due to how features being selected were in a binary search space. Binary Multi-Neighborhood Artificial Bee Colony (BMNABC) was chosen as an alternative. The comparison indicated that BMNABC increased the accuracy to as high as 90.57% and can be regarded as a promising method for identifying implicit learning events.
那些擅长内隐学习的人可以更快地学习东西,在快节奏的信息时代更能适应。内隐学习是一种没有明确教导的学习。这种情况常见于年龄较小的孩子,他们在没有学习语法的情况下发展说母语的能力。人类的大脑可以通过训练大脑更经常地处于学习的状态来训练出善于学习的能力。通过使用神经反馈来调节人类的大脑状态,教育者和学习者可以互相帮助,训练大脑成为更好的内隐学习者。我们的研究旨在对脑电信号中的内隐学习事件进行分类,以帮助识别和调节这种状态。本文分析了特征选择过程部分,以提高分类性能。我们在进行认知任务实验时使用了先前测量的参与者的脑电图信号。然后将这些信号的特征提取到多尺度熵中。以前,人工蜂群(Artificial Bee Colony, ABC)在多尺度熵上被用来帮助内隐学习事件分类,并取得了一定的成功。然而,由于在二进制搜索空间中选择特征的方式,需要进行改进以使整个系统更加优化。选择二元多邻域人工蜂群(BMNABC)作为替代方案。结果表明,BMNABC的准确率高达90.57%,是一种很有前途的内隐学习事件识别方法。
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引用次数: 0
Reconstruction of 3D Abdominal Aorta Aneurysm from Computed Tomographic Angiography Using 3D U-Net Deep Learning Network 利用三维U-Net深度学习网络重建三维腹主动脉瘤
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012097
Siriporn Kongrat, C. Pintavirooj, S. Tungjitkusolmun
(1) Background: An abdominal aortic aneurysm (AAA) is a swelling (aneurysm) of the aorta that occurs when the wall of the aorta weakens. An AAA is a potentially life-threatening condition, especially if it eventually ruptures, causing severe bleeding. (2) Methods: We developed an automated segmentation method for 3D AAA reconstruction from computed tomography angiography (CTA) based on the 3D U-NET deep learning network approaches for AAA and AAA with thrombus on training dataset classified as 8 normal, 14 aneurysm volume, and 38 thrombus aneurysm volume with the data augmentations app, i.e., scaling, random crop, grayscale variation, axial y flip, and shear, were added to the training model, achieving better performance. (3) Results: The results confirm that the proposed method can provide accuracy in terms of the Dice Similar Coefficient (DSC) scores of 0.9669 for training performance and 0.9868 for testing evaluation with the 3D U-Net model.
(1)背景:腹主动脉瘤(AAA)是当主动脉壁变弱时发生的主动脉肿胀(动脉瘤)。AAA是一种潜在的危及生命的疾病,特别是如果它最终破裂,导致严重出血。(2)方法:基于三维U-NET深度学习网络,在训练模型中加入缩放、随机裁剪、灰度变化、y轴向翻转、剪切等数据增强应用程序对训练数据集上的AAA和带有血栓的AAA分别分类为8正常、14动脉瘤体积和38血栓动脉瘤体积,开发了一种基于ct血管成像(CTA)的三维AAA重建自动分割方法,获得了更好的性能。(3)结果验证了本文方法的准确性,训练性能的DSC分数为0.9669,3D U-Net模型测试评价的DSC分数为0.9868。
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引用次数: 0
A radiopathomics model for prognosis prediction in patients with gastric cancer 胃癌患者预后预测的放射病理学模型
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012107
Yuanshen Zhao, Jingxian Duan, Zhicheng Li, N. Chai, Longsong Li
Predicting gastric cancer prognosis is imperative for more appropriate clinical treatment plans. Compared with traditional radiomics model adopting CT images alone, the radiopathomics is a novel medical image analysis strategy which employed the radiomcs features extracted from CT image and pathomics features extracted from pathological image to build a prediction model. In this paper, we developed a radiopathomics model to predict whether patients with gastric cancer survive more than 2 years. By using LASSO algorithm, two pathomics features, a radiomics feature and the clinical variables of TNM were selected from totally 1565 features to build the prediction model. For reflecting the advantage of the radiopathomics model, we implemented the comparison tests between the radiopathomics model with radiomics model and pathomics model. The results showed that the radiopathomics model achieved an AUC of 0.904 and an accuracy of 84.2%, which was significantly better than the other two models. It demonstrated that integrated of the microscopic level and macroscopic level phenotype information for tumor could be useful in prediction of prognosis.
预测胃癌预后对于制定更合理的临床治疗方案至关重要。与传统的仅采用CT图像的放射组学模型相比,放射病理组学是一种利用从CT图像中提取的放射组学特征和从病理图像中提取的病理特征来构建预测模型的新型医学图像分析策略。在本文中,我们建立了一个放射病理学模型来预测胃癌患者是否存活超过2年。采用LASSO算法,从1565个特征中选择2个病理特征、1个放射组学特征和TNM的临床变量建立预测模型。为了体现放射病理组学模型的优势,我们对放射病理组学模型与放射组学模型和病理模型进行了比较试验。结果表明,放射病理学模型的AUC为0.904,准确率为84.2%,明显优于其他两种模型。结果表明,结合微观和宏观水平的肿瘤表型信息可用于预测预后。
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引用次数: 0
期刊
2022 14th Biomedical Engineering International Conference (BMEiCON)
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