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2022 14th Biomedical Engineering International Conference (BMEiCON)最新文献

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Precise Motor Function Monitor for Parkinson Disease using Low Power and Wearable IMU Body Area Network 基于低功耗可穿戴IMU体域网络的帕金森病精确运动功能监测
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012114
W. Chang, K. Liou, Yo-Tsen Liu, K. Wen
The Inertial Measurement Unit (IMU) has been widely used in precision movement analysis and evaluation and applied in the diagnosis and treatment of many diseases. Parkinson disease (PD) is the most common neurodegenerative movement disorder with rest tremor, bradykinesia, and rigidity as the cardinal motor manifestations. A novel algorithm system has been derived to detect all the motor examinations of the Unified Parkinson's Disease Rating Scale (UPDRS), of which the accuracy has been verified by high-speed camera system. This system includes three categories of detection parameters: the trajectory parameters, time-frequency parameters, angle parameters. Average accuracy for the detection with IMU can reach to 87%, 90% and 95%, respectively.With 17 patients’ trial tests, it’s observed that there do have certain differences of the movement parameters in between patients and age 20th youth controls. For 3.6 Pronation and Supination, the rotation speed of normal control can be twice of the patients and the deviation of the amplitude can reach to 45 degrees of patient in comparison to 5 degrees of normal control. Also, for low power and wearable requirements, this processing system have been designed with chip solution and be implemented with TSMC 0.18 mm CMOS process. The power consumption is 0.3713mW and the chip area is 4.2mm by 4.2mm which will be well suited to wearable applications.Our results showed that this processing system could precisely measure the temporal patterns of speed and amplitude decay of the movements, and successfully capture the severity and difference of bradykinesia and poor coordination of the patients of PD.
惯性测量单元(IMU)已广泛用于精密运动分析和评估,并在许多疾病的诊断和治疗中得到应用。帕金森病(PD)是最常见的神经退行性运动障碍,以静止性震颤、运动迟缓和僵硬为主要运动表现。本文推导了一种新的算法系统,用于检测统一帕金森病评定量表(UPDRS)的所有运动检查,并通过高速摄像系统验证了其准确性。该系统包括三大类检测参数:弹道参数、时频参数、角度参数。IMU检测的平均准确率分别可达87%、90%和95%。通过17例患者的试验测试,观察到患者的运动参数与20岁青年对照有一定的差异。对于3.6旋前和旋后,正常控制的旋转速度可以是患者的两倍,与正常控制的5度相比,振幅的偏差可以达到患者的45度。此外,为了满足低功耗和可穿戴的要求,该处理系统采用芯片解决方案设计,并采用台积电0.18 mm CMOS工艺实现。功耗为0.3713mW,芯片面积为4.2mm × 4.2mm,非常适合可穿戴应用。结果表明,该处理系统能够精确测量运动速度和振幅衰减的时间模式,并成功捕获PD患者运动迟缓和协调性差的严重程度和差异。
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引用次数: 0
Classification of Depression Audio Data by Deep Learning 基于深度学习的抑郁症音频数据分类
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012102
Phanomkorn Homsiang, T. Treebupachatsakul, Komsan Kiatrungrit, Suvit Poomrittigul
Due to many factors such as anxiety from contracting the disease and concern about the socioeconomic impacts, Thai people have accumulated stress and are at risk of depression. The diagnosis of depression can be primarily assessed by testing the assessments such as PHQ8, PHQ-9, and CES-D. The applied deep learning technology in medicine has received research interest and has been developing. In this research, we tried the classification of depression and non-depression audio datasets with the implementation of 4 model architectures: 1D CNN, 2D CNN, LSTM, and GRU. By converting wave audio format (WAV) of Daic-woz database to the Melfrequency cepstrum (MFC). We have done the training and evaluated the 4 model architectures and compared the results between non-augmented and augmented datasets. The highest accuracy was obtained from 1D CNN with a non-data augmentation of 95%, and a 2D CNN with a data augmentation of 75%. These results confirm that human voices can differentiate between depression and non-depression.
由于许多因素,如感染疾病的焦虑和对社会经济影响的担忧,泰国人已经积累了压力,并有抑郁的风险。抑郁症的诊断主要通过PHQ8、PHQ-9、CES-D等测试进行评估。深度学习技术在医学上的应用已经引起了人们的研究兴趣,并一直在发展。在本研究中,我们尝试通过4种模型架构实现抑郁和非抑郁音频数据集的分类:1D CNN、2D CNN、LSTM和GRU。通过将Daic-woz数据库的波形音频格式(WAV)转换为Melfrequency倒频谱(MFC)。我们完成了4种模型架构的训练和评估,并比较了非增强和增强数据集之间的结果。非数据增强率为95%的1D CNN和数据增强率为75%的2D CNN准确率最高。这些结果证实,人类的声音可以区分抑郁和非抑郁。
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引用次数: 0
A compact water loaded choke configurations for intracavitary microwave hyperthermia 一种用于腔内微波热疗的紧凑的水负载扼流圈配置
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012117
K. Shabeeb Ahamed, K. Arunachalam
This paper presents a compact water-loaded coaxial balun configurations for targeted heat delivery for intracavitary hyperthermia treatment of cancer. Balun configurations of choke were analyzed using a 3$lambda$/8 monopole at 915 MHz. The surface current density and volume loss density characteristics were used to evaluate balun efficiency and were compared with a conventional monopole without balun. The antenna performance with and without the balun configurations was numerically assessed and compared in terms of specific absorption rate (SAR) and input power reflection coefficient. The numerical designs were experimentally validated in muscle mimicking liquid phantoms.
本文提出了一种紧凑的水负载同轴平衡配置,用于腔内热疗治疗癌症的靶向热输送。使用915 MHz的3$lambda$/8单极分析扼流圈的平衡配置。利用表面电流密度和体积损耗密度特性来评价平衡效率,并与不加平衡的传统单极子进行了比较。采用平衡器配置和不配置平衡器的天线性能进行了数值评估,并在比吸收率(SAR)和输入功率反射系数方面进行了比较。数值设计在肌肉模拟液体幻影中得到了实验验证。
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引用次数: 0
Attempts at Enhancing eVision’s Influenza Forecasting Using Social Media 利用社交媒体增强eVision流感预测的尝试
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012095
Navid Shaghaghi, Yash Kamdar, Ron Huang, A. Calle, Jaidev Mirchandani, Michael Castillo
Prediction of the spread of infectious diseases such as the seasonal Influenza is of utmost importance in the preparation for and mitigation of the severity of their impact. eVision (short for Epidemic Vision) is a machine learning time series forecaster under research and development by Santa Clara University’s EPIC (Ethical, Pragmatic, and Intelligent Computing) and BioInnovation & Design laboratories. Since eVision’s Long Short-Term Memory (LSTM) neural network makes use of Influenza related keywords in Google Trends as prediction features, it stands to reason that further feature selection from trending keywords relating to the flu in social media posts could enhance its prediction. After close examination, the only social media platforms that prove capable of supplying relevant data for time series analysis are the Twitter micro-blogging and Reddit social news aggregation and discussion forum platforms; as other social media platforms are either meant for sharing images and videos, or private multi-cast communication rather than public broadcasting and discourse. However, due to the burstiness of flu related Reddit posts, no useful feature for time series forecasting can be extracted from that platform; and Twitter, which has been examined for Influenza forecasting by numerous other researchers with successful results, poses a number of obstacles such as changes in policy as well as placing features behind expensive paywalls through the disabling of existing free APIs. Regardless however, the results obtained by the addition of Twitter data as another feature in eVision’s LSTM resulted in an almost negligible predictive improvement as delineated in this paper.
对季节性流感等传染病的传播进行预测,对于防备和减轻其严重影响至关重要。evvision(流行病视觉的缩写)是由圣克拉拉大学EPIC(伦理、实用和智能计算)和生物创新与设计实验室研发的机器学习时间序列预测器。由于eVision的长短期记忆(LSTM)神经网络利用谷歌趋势中与流感相关的关键词作为预测功能,因此从社交媒体帖子中与流感相关的趋势关键词中进一步选择特征可以增强其预测功能。经过仔细研究,能够提供相关数据进行时间序列分析的社交媒体平台只有Twitter微博和Reddit社交新闻聚合论坛平台;因为其他社交媒体平台要么是为了分享图片和视频,要么是私人多播通信,而不是公共广播和话语。然而,由于Reddit上与流感相关的帖子层出不穷,无法从该平台提取出有用的时间序列预测功能;Twitter已经被许多其他研究人员用于流感预测,并取得了成功的结果,但它提出了许多障碍,比如政策的变化,以及通过禁用现有的免费api将功能置于昂贵的付费墙之后。然而,无论如何,通过在eVision的LSTM中添加Twitter数据作为另一个特征所获得的结果导致了本文所描述的几乎可以忽略不计的预测改进。
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引用次数: 1
A ventilator circuit for volume control mode 用于音量控制模式的通风机电路
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10011580
A. Sanpanich, N. Komalawardhana, K. Petsarb
An automatic ventilator is used to treat patient who has abnormality in respiratory system or spontaneous ventilation is not enough to maintain blood oxygen and carbondioxide level in normal level. It functions to provide a fresh gas flow into patient lungs during an inspiration and remove exhaled gas from lungs during an expiration. Ventilator is known as the most complicated equipment in ICU due to a parameter setting, waveform understanding and variation of patient pathological variable under controlled ventilation which affect to ventilator operation. Then, new user always need time to practice and familiar with ventilator. In this paper, we present a simplified ventilator model by using an effective simulation tools in order to use as a simple tool in ventilation parameter study. The proposed ventilator simulation is basically based on volume control ventilation mode (VCV) with focusing on PEEP setting at expiratory module. We also simulated an operation of O2 concentrator in gas supply module which is designed by using parallel flow system of both air and oxygen. As a preliminary, all main ventilation waveforms $(mathrm{P}_{aw}, mathrm{V}_{T}$, $dot{V}, mathrm{T}_{P}$, PEEP, O2%) obtain from this modified model show an effective response and be able to use as a routine practice for new practitioner. For further study, another basic ventilation mode and setting as PCV, IMV even patient triggering setting will be added in the future.
自动呼吸机用于治疗呼吸系统异常或自发通气不足以维持血氧和二氧化碳水平在正常水平的患者。它的功能是在吸气时向患者肺部提供新鲜气体,并在呼气时从肺部排出呼出的气体。呼吸机被认为是ICU中最复杂的设备,在控制通气条件下,呼吸机的参数设置、波形理解以及患者病理变量的变化都会影响到呼吸机的操作。然后,新用户总是需要时间来练习和熟悉呼吸机。本文利用一种有效的仿真工具,提出了一种简化的通风机模型,以期为通风机参数的研究提供一种简便的工具。本文提出的呼吸机模拟基本基于容积控制通气模式(VCV),重点关注呼气模块的PEEP设置。本文还模拟了采用空气与氧气平行流动系统设计的供气模块中氧气浓缩器的运行情况。初步得到的主要通气波形$(mathrm{P}_{aw}, mathrm{V}_{T}$, $dot{V}, mathrm{T}_{P}$, PEEP, O2%)均有较好的响应,可作为新手的常规练习。为进一步研究,未来将增加PCV、IMV甚至患者触发设置等另一种基本通气模式和设置。
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引用次数: 0
Joint space narrowing progression quantification with joint angle correction in rheumatoid arthritis 类风湿关节炎关节间隙狭窄进展量化与关节角度矫正
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012092
Yafei Ou, P. Ambalathankandy, Ryunosuke Furuya, Seiya Kawada, Tamotsu Kamishima, M. Ikebe
Rheumatoid arthritis is a form of autoimmune disease characterized by synovitis that can ultimately cause joint deformities and impaired functioning. The cartilage destruction is one of the most important indicators for diagnosis and treatment of Rheumatoid arthritis, and it is radiographically manifested as joint space narrowing. In this study, we propose a joint location detection method and a sub-pixel accurate method for quantifying joint space narrowing progression with a joint angle correction. The proposed joint location detection method can detect the location of 14 joints from a given hand radiographic image, the error of 89.13% joints is less than 3 pixels (spatial resolution: 0.175 mm/pixel). In our previous works, we measured joint space narrowing progression between a baseline and its follow-up finger joint images by using partial image phase only correlation. We found that the inconsistency of joint angles may lead to characteristic mismatch and thus affect the accuracy of joint space narrowing quantification. In this work, we introduce rotation invariant phase only correlation in joint space narrowing quantification for joint angle correction. In our experiment, the improved quantification method can effectively manage the mismatch due to the inconsistency of joint angles.
类风湿性关节炎是一种以滑膜炎为特征的自身免疫性疾病,最终可导致关节畸形和功能受损。软骨破坏是类风湿关节炎诊断和治疗的重要指标之一,影像学表现为关节间隙狭窄。在本研究中,我们提出了一种关节位置检测方法和一种亚像素精度的方法,用于量化关节角度校正的关节空间缩小进程。所提出的关节位置检测方法可以从给定的手部放射图像中检测出14个关节的位置,关节的误差为89.13%,误差小于3个像素(空间分辨率:0.175 mm/像素)。在我们之前的工作中,我们通过使用部分图像相位仅相关来测量基线和后续手指关节图像之间的关节间隙缩小进展。研究发现,关节角度的不一致可能导致特征失配,从而影响关节空间缩小量化的准确性。本文在关节空间缩小量化中引入旋转不变相位相关,用于关节角度校正。在我们的实验中,改进的量化方法可以有效地管理由于关节角度不一致而导致的失配。
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引用次数: 1
A control system in a micro cone-beam CT machine 微型锥束CT机的控制系统
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012087
Atthasak Kiang-Ia, Sathid Rukkhong, T. Srivongsa, Kittipong Kasantikul, Chalinee Thanasupsombat, S. Aootaphao, S. Thongvigitmanee
Images data from the micro cone-beam computed tomography (CBCT) are acquired from a rotation of an object located between an X-ray generator and a flat panel detector; therefore, the rotational position of the motor is very important for image quality of 3D cross-section images. This study focuses on designing the position control of the stepping motor using the motion module, which enhances the control 4-axis motor’s efficiency to optimize and increase the accuracy of motor movement. We designed the stepping motor position control system to control the movement of the micro CBCT system to perform ten circular rotations in a single scanning process. A phantom was used to verify the rotational image accuracy by considering the image at the same position each round. Comparison of the motor movement with and without the motion module showed slight differences of projection images causing artifacts in cross-section images. Thus, the design of the rotation position control using the motion module circuit yielded good performance in terms of precision and rotational accuracy on the CBCT.
来自微锥束计算机断层扫描(CBCT)的图像数据是通过位于x射线发生器和平板探测器之间的物体的旋转获得的;因此,电机的旋转位置对三维截面图像的成像质量非常重要。本研究重点是利用运动模块设计步进电机的位置控制,提高控制四轴电机的效率,优化和提高电机的运动精度。我们设计了步进电机位置控制系统来控制微CBCT系统的运动,使其在一次扫描过程中进行10圈旋转。通过考虑每轮在相同位置的图像,使用一个幻像来验证旋转图像的精度。运动模组与无运动模组的运动模组对比显示,运动模组的投影图像略有差异,导致横截面图像出现伪影。因此,使用运动模块电路设计的旋转位置控制在CBCT上的精度和旋转精度方面取得了良好的性能。
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引用次数: 0
A Comparison Between Wavelet Scattering Transform and Transfer Learning for Elevated Blood Pressure Detection 小波散射变换与迁移学习在高血压检测中的比较
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012088
E. Martinez-Ríos, L. Montesinos, Mariel Alfaro
Hypertension is a health issue whose late diagnosis could lead to renal, cerebral, and cardiac events. In this work, it is proposed to use the wavelet scattering transform (WST) as a feature extraction technique applying classical machine learning techniques using photoplethysmography (PPG) signals as input to detect elevated blood pressure and compare its performance with transfer learning applied through fine-tuned convolutional neural networks. The results show that the features obtained by applying the WST and training a logistic regression and support vector machine produced similar results in terms of accuracy compared to fine-tuned convolutional neural networks, with the advantage that the WST could be used to generate a white-box model, which is better suited for a potential medical diagnosis application.
高血压是一种健康问题,其晚期诊断可能导致肾脏、大脑和心脏事件。在这项工作中,提出使用小波散射变换(WST)作为特征提取技术,应用经典机器学习技术,使用光容积脉搏波(PPG)信号作为输入来检测血压升高,并将其性能与通过微调卷积神经网络应用的迁移学习进行比较。结果表明,与微调卷积神经网络相比,应用WST并训练逻辑回归和支持向量机获得的特征在准确性方面产生了相似的结果,并且WST可以用于生成白盒模型,这更适合潜在的医疗诊断应用。
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引用次数: 2
Printability and cytotoxicity of alginate/agarose hydrogel with carboxylmethyl cellulose and apple powder 羧甲基纤维素和苹果粉混合海藻酸盐/琼脂糖水凝胶的印刷性和细胞毒性
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012110
K. Chessadangkul, N. Damrongplasit, S. Morakul, T. Tharasanit, A. Pimpin
The cultured meat is the solution to reduce resources using in a traditional meat production. It helps produce meat without killing livestock and decrease residue products. The method could also integrate with scaffold’s material which does not derive from animal products. This study aims to investigate the effects of carboxymethyl cellulose (CMC) and apple powder on printability and cytotoxicity as additives in alginate/agarose-based hydrogel. 3D structures of them were printed to find a proper printing condition. From our experiments, the structure could maintain their shapes and uniform line sizes for carboxylmethyl cellulose, but not for apple powder at the 2% w/v alginate and 0.8% w/v agarose. However, the combination of them could be printed well. In parallel, 293FT cells were cultured with hydrogel drop to test cytotoxicity. It showed that the hydrogel with both additives does not harm cells during 8-day culturing.
培养肉是减少传统肉类生产中资源使用的解决方案。它有助于在不杀死牲畜的情况下生产肉类,并减少残留产品。该方法还可以与非动物制品的支架材料相结合。本研究旨在研究羧甲基纤维素(CMC)和苹果粉作为海藻酸盐/琼脂糖基水凝胶添加剂对打印性和细胞毒性的影响。对其三维结构进行打印,寻找合适的打印条件。实验结果表明,在2% w/v海藻酸盐和0.8% w/v琼脂糖溶液中,羧甲基纤维素的结构可以保持其形状和均匀的线尺寸,而苹果粉则不能。然而,它们的组合可以很好地打印。同时用水凝胶滴液培养293FT细胞,检测细胞毒性。结果表明,添加两种添加剂的水凝胶在8 d的培养过程中对细胞无损伤。
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引用次数: 0
Real-Time Epilepsy Detection with IMU and Low Power Processor Design 基于IMU和低功耗处理器的实时癫痫检测设计
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012112
Yu-Ju Su, K. Wen, M. Cheng, Chen-Nen Chang
In this work, we proposed a system that supplies real-time epilepsy detection system (RED system) with a single inertial measurement unit (IMU) and a low power processing unit. Since the accuracy can reach 99.81%, the specificity can reach 99.81%, and false positive rate of 0.19%, it not only ensures reliability but also provides a quantification analysis for diagnosis. The proposed method has been verified by 60 patients and the processing unit has been implemented into a chip using TSMC 0.18 μm process, which proves the feasibility of mobile device to the RED system.
在这项工作中,我们提出了一种提供实时癫痫检测系统(RED系统)的系统,该系统具有单惯性测量单元(IMU)和低功耗处理单元。准确率可达99.81%,特异性可达99.81%,假阳性率为0.19%,既保证了可靠性,又为诊断提供了定量分析。该方法已通过60例患者验证,并采用TSMC 0.18 μm工艺将处理单元实现在芯片上,证明了移动设备对RED系统的可行性。
{"title":"Real-Time Epilepsy Detection with IMU and Low Power Processor Design","authors":"Yu-Ju Su, K. Wen, M. Cheng, Chen-Nen Chang","doi":"10.1109/BMEiCON56653.2022.10012112","DOIUrl":"https://doi.org/10.1109/BMEiCON56653.2022.10012112","url":null,"abstract":"In this work, we proposed a system that supplies real-time epilepsy detection system (RED system) with a single inertial measurement unit (IMU) and a low power processing unit. Since the accuracy can reach 99.81%, the specificity can reach 99.81%, and false positive rate of 0.19%, it not only ensures reliability but also provides a quantification analysis for diagnosis. The proposed method has been verified by 60 patients and the processing unit has been implemented into a chip using TSMC 0.18 μm process, which proves the feasibility of mobile device to the RED system.","PeriodicalId":177401,"journal":{"name":"2022 14th Biomedical Engineering International Conference (BMEiCON)","volume":"48 16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129944609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
2022 14th Biomedical Engineering International Conference (BMEiCON)
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