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2022 14th Biomedical Engineering International Conference (BMEiCON)最新文献

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SNR estimation in EMG signals contaminated with motion artifact 运动伪影污染的肌电信号信噪比估计
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012080
Thandar Oo, P. Phukpattaranont
An electromyography (EMG) recognition system is essential for enabling a variety of applications. However, motion artifact contaminated with the EMG signal as it passes through or by various tissues may degrade the recognition performance. We present the algorithm for signal-to-noise ratio (SNR) estimation in EMG signals contaminated with motion artifact. Six features derived from the EMG signals are used as the neural network input: skewness (SKEW), kurtosis (KURT), mean absolute value (MAV), wavelength (WL), zero crossing (ZC), and mean frequency (MNF). The estimated SNR values are the neural network output. The best mean and standard deviations of the correlation coefficient (CC) between the actual and estimated SNR values are provided by the MNF $(0.9699 pm 0.0076)$. Future research may concentrate on determining SNR values using real EMG signals in their natural surroundings.
肌电(EMG)识别系统对于实现各种应用是必不可少的。然而,当肌电图信号通过或被各种组织污染时,运动伪影可能会降低识别性能。提出了一种运动伪影污染的肌电信号信噪比估计算法。从肌电信号中提取的六个特征被用作神经网络的输入:偏度(SKEW)、峰度(KURT)、平均绝对值(MAV)、波长(WL)、过零(ZC)和平均频率(MNF)。估计的信噪比值是神经网络的输出。实际信噪比值和估计信噪比值之间的相关系数(CC)的最佳平均值和标准差由MNF $(0.9699 pm 0.0076)$提供。未来的研究可能会集中在确定信噪比值,使用真实的肌电信号在他们的自然环境。
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引用次数: 0
Detection of Creatinine Using Molecularly Imprinted Polymers (MIP) Technique 分子印迹聚合物(MIP)技术检测肌酐
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10011578
Teerachote Pitayataratorn, Wannisa Sukjee, C. Sangma, S. Visitsattapongse
An electrochemical potentiometric biosensor based on the molecularly imprinted polymer (MIP) technique has been fabricated for creatinine detection. The polymer consists of azobisisobutyronitrile (AIBN) as an initiator together with N, N’(1,2-Dihydroxyethelene) bisacrylamide (DHEBA) as a cross-linker and graphene oxide (GO) was prepared along with several functional monomers combination to compare each combination’s effectiveness in the detection of creatinine. An experiment was divided into imprint and non-imprint polymer for imprinting effectiveness evaluation. Creatinine anhydrous were used as template molecules for imprinting the polymer. The analyte was prepared in buffer solution (PBS) at a pH of 7.4 with a concentration range from 0.01 mg/dl to 100 mg/dl. N-hydroxy succinimide (NHS) and D-glucose were used for the specificity test. This study can conclude that polymers consisting of functional monomer methyl methacrylate (MMA) and acrylamide (AAM) with a 1:1 ratio show significant sensitivity to creatinine with the detection limit of 0.1 mg/dl along with remarkable selectivity to creatinine against other negative control compared to other conditions in this study and the sensor has a response linearly ranges from 0.01 to 100 mg/dl.
制备了一种基于分子印迹聚合物(MIP)技术的电化学电位生物传感器,用于检测肌酐。该聚合物由偶氮二异丁腈(AIBN)为引发剂,N, N '(1,2-二羟乙烯)双丙烯酰胺(DHEBA)为交联剂,氧化石墨烯(GO)与几种功能单体组合组成,比较了每种组合检测肌酐的有效性。实验分为压印聚合物和非压印聚合物进行压印效果评价。无水肌酐作为模板分子印迹聚合物。在pH为7.4的缓冲溶液(PBS)中制备分析物,浓度范围为0.01 mg/dl至100 mg/dl。特异性试验采用n -羟基琥珀酰亚胺(NHS)和d -葡萄糖。本研究表明,与本研究中其他条件相比,功能单体甲基丙烯酸甲酯(MMA)和丙烯酰胺(AAM)按1:1的比例组成的聚合物对肌酐具有显著的灵敏度,检测限为0.1 mg/dl,对其他阴性对照具有显著的选择性,传感器的响应线性范围为0.01 ~ 100 mg/dl。
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引用次数: 0
Detection of Mineral (Ca/Fe) Concentration in Blood Using the Complex Bioimpedance 复合生物阻抗法检测血钙铁浓度
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012090
L. Szolga
The objective of this paper was to implement a portable, small, minimally invasive system for detecting blood mineral concentrations. The goal was to find a relationship between impedance changes in solutions with different iron and calcium concentrations to subsequently find a correlation between the impedance of a healthy patient’s blood and blood with a mineral deficiency or excess. The system was built around the AD5933 integrated circuit, which validated complex bioimpedance well. The prototype operates in the 10-100 kHz range and is suitable for a single frequency, multifrequency point, or spectroscopic measurements.
本文的目的是实现一个便携式,小型,微创系统检测血液矿物质浓度。目的是找到不同铁和钙浓度溶液中阻抗变化之间的关系,从而找到健康患者血液阻抗与矿物质缺乏或过量血液之间的相关性。该系统以AD5933集成电路为核心,能够很好地验证复杂的生物阻抗。该样机工作在10-100 kHz范围内,适用于单频、多频点或光谱测量。
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引用次数: 0
Detection and Classification of COVID-19 Chest X-rays by the Deep Learning Technique 基于深度学习技术的COVID-19胸部x线检测与分类
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012094
Wannika Sonarra, Naphatsawan Vongmanee, Nutthanan Wanluk, C. Pintavirooj, S. Visitsattapongse
The Coronavirus disease (COVID-19) infection has become a pandemic, and this is the most critical problem that has occurred in Thailand and also expanded all over the world. As such, it is not astonishing to know that this virus has had a direct effect on hospitals with the delayed screening of patients because of the increasing number of daily cases and the shortage of medical personnel and restricted treatment space. Due to such restrictions, in this study, we used a clinical decision-making system with predictive algorithms. Predictive algorithms could potentially ease the strain on healthcare systems by identifying the diseases. Moreover, image classification is one interesting aspect of image processing. Convolutional neural network (CNN) is a widely used algorithm for image classification by separating the images of the COVID-19 disease, images with a lung infection, and normal images. To evaluate the predictive performance of our models, precision, F1-score, recall, receiver operating characteristic (ROC) curve (area under the ROC curve), and accuracy scores were used. It was observed that the predictive models trained on the laboratory findings could be used to predict the COVID-19 infection as well and could be helpful for medical experts to appropriately prioritize the resources. This could be employed to assist medical experts in validating their initial laboratory findings and could also be used for clinical prediction studies.
冠状病毒病(COVID-19)感染已成为大流行,这是发生在泰国并扩展到世界各地的最关键问题。因此,这种病毒对医院产生了直接影响,因为每天的病例增加,医疗人员短缺和治疗空间有限,导致患者筛查延迟,这并不令人惊讶。由于这些限制,在本研究中,我们使用了具有预测算法的临床决策系统。预测算法可能会通过识别疾病来缓解医疗系统的压力。此外,图像分类是图像处理中一个有趣的方面。卷积神经网络(CNN)是一种广泛使用的图像分类算法,可以将COVID-19疾病图像、肺部感染图像和正常图像分开。为了评估我们的模型的预测性能,使用了精度、f1评分、召回率、受试者工作特征(ROC)曲线(ROC曲线下面积)和准确性评分。观察到,根据实验室结果训练的预测模型也可用于预测COVID-19感染,并有助于医学专家合理分配资源。这可用于协助医学专家验证其初步实验室发现,也可用于临床预测研究。
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引用次数: 1
Statistical Representation of Emotions for Puzzle Workload using Electroencephalogram and Heart Rate Variability 利用脑电图和心率变异性对智力游戏工作负荷情绪的统计表征
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012068
T. Igasaki, Aoi Takahi, Saori Nishikawa
We attempted to express the psychological quantity of executing workload through statistical analysis of indices extracted from an electroencephalogram (EEG) and a heart rate variability (HRV) score of subjects when they were asked to solve jigsaw puzzles. First, we conducted a regression analysis of the emotional score of the mood evaluation questionnaire after the completion of the workload and the indices of the EEG and HRV before and after the start and completion of the workload, and thereafter confirmed the strongest correlation before the completion of the workload. Next, we conducted a principal component analysis of the indices of the EEG and HRV before the completion of the workload, and thereafter confirmed that three principal components were obtained that correlated with “friendship,” “fatigue-inertia,” and “vigor-activity” in the mood evaluation questionnaire. Therefore, we demonstrated that the physiological quantities of the EEG and HRV indices could statistically express the psychological quantities of positive/negative emotions, even with small data.
我们试图通过统计分析从被试者的脑电图(EEG)和心率变异性(HRV)得分中提取的指标来表达执行工作量的心理量。首先,我们对工作负荷完成后的情绪评价问卷的情绪得分与工作负荷开始和完成前后的EEG和HRV指标进行回归分析,确认工作负荷完成前的相关性最强。接下来,我们对工作量完成前的EEG和HRV指标进行主成分分析,确认得到与情绪评价问卷中的“友谊”、“疲劳-惯性”和“活力-活动”相关的三个主成分。因此,我们证明了EEG和HRV指标的生理量可以统计地表达积极/消极情绪的心理量,即使数据很少。
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引用次数: 0
Nanoliposome of Linolenic acid for Methicillin-resistant Staphylococcus aureus treatment 用于耐甲氧西林金黄色葡萄球菌治疗的亚麻酸纳米脂质体
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012101
Azmee Okriss, Julinthip Puttawong, Mingkwan Yingkajorn, Somyot Chirasatitsin, Soracha D. Thamphiwatana
Methicillin-resistant Staphylococcus aureus (MRSA) presents a major threat to a broad range of healthcare and community associated infections. MRSA bacteria have rapidly developed resistance to multiple drugs throughout the antibiotic history. It is imperative to develop novel antimicrobial strategies to address the currently shrinking therapeutic options against MRSA. Herein, we developed a nanoliposome formulation of natural antimicrobial compound such as linolenic acid and evaluate its potential application for the treatment of MRSA infection as well as its safety. We found that Nano-liposomal linolenic acid (LipoLNA) was successfully synthesized. LipoLNA was able to inhibit MRSA growth and exhibited a good safety profile on normal mammalian cells.
耐甲氧西林金黄色葡萄球菌(MRSA)对广泛的医疗保健和社区相关感染构成重大威胁。在整个抗生素历史中,MRSA细菌迅速对多种药物产生耐药性。必须开发新的抗微生物策略,以解决目前针对MRSA的治疗方案不断缩小的问题。在此,我们开发了一种天然抗菌化合物如亚麻酸的纳米脂质体配方,并评估其在治疗MRSA感染方面的潜在应用及其安全性。我们成功合成了纳米亚麻酸脂质体(LipoLNA)。LipoLNA能够抑制MRSA的生长,并在正常哺乳动物细胞中表现出良好的安全性。
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引用次数: 0
Classification model for predicting inflammation of the urinary bladder and acute nephritis of the renal pelvis 预测膀胱炎症和急性肾盂肾炎的分类模型
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012109
Chanin Lochotinunt, Suejit Pechprasarn, T. Treebupachatsakul
Urinary tract diseases can occur in many organs of the urinary system, such as kidneys, urinary bladder, renal pelvis, ureters, and urethra. The most common disease in the urinary system is bladder inflammation, cystitis, and acute nephritis. In this research, the classification artificial intelligent model is applied to predict 2 symptoms of inflammation of the urinary bladder and acute nephritis of the renal pelvis from 6 parameters, including body temperature of patient, nausea, lumbar pain, urinary pushing, micturition pains, and burning of the urethra. Here, the principal components analysis or PCA are also applied to identify the critical parameters employed to train the machine learning model. Here, we propose to compare several machine learning classification models and show the proper model accurately diagnosing these two symptoms.
泌尿系统疾病可发生在泌尿系统的许多器官,如肾脏、膀胱、肾盂、输尿管和尿道。泌尿系统最常见的疾病是膀胱炎症、膀胱炎和急性肾炎。本研究应用分类人工智能模型从患者体温、恶心、腰痛、尿推、排尿痛、尿道灼烧6个参数预测膀胱炎症和急性肾盂肾炎2种症状。这里,主成分分析或PCA也被用于识别用于训练机器学习模型的关键参数。在这里,我们建议比较几种机器学习分类模型,并展示准确诊断这两种症状的合适模型。
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引用次数: 0
Finite element analysis of plantar pressure distribution in diabetic foot during stance phase of the gait cycle without and with custom-made insole 无定制鞋垫和有定制鞋垫时糖尿病足站立阶段足底压力分布的有限元分析
Pub Date : 2022-11-10 DOI: 10.1109/BMEiCON56653.2022.10012093
M. Nouman, S. Chatpun
Diabetic foot complications tend to increase plantar pressure distribution increasing the chances of ulceration and re-ulceration. The knowledge about the factors associated with the causes of ulceration and effective offloading still lacks. Custom-made insole (CMI) is one of offloading techniques. This study aimed to investigate the plantar pressure distribution with shod gait and with CMI during stance phase of the gait cycle using a finite element (FE) approach. A subject-specific three-dimensional model without and with CMI was constructed. The ground reaction force from the experimental study was applied to the FE foot model during different phases of the gait cycle. The peak contact pressure was reduced with the use of CMI from all phases of the gait cycle. Moreover, frictional stress was reduced especially from the forefoot at midstance and terminal stance of the gait cycle. CMI redistributed the plantar pressure and tends to reduce the frictional stress during stance phase of the gait cycle. FE analysis provides better understanding of different parameters that are difficult to calculate with the conventional method. The FE analysis ease the investigation of various conditions including without and with CMI during different phases of the gait cycle.
糖尿病足并发症往往增加足底压力分布,增加溃疡和再溃疡的机会。有关溃疡的原因和有效卸载的相关因素的知识仍然缺乏。定制鞋垫(CMI)是一种卸载技术。本研究旨在利用有限元方法研究穿鞋步态和CMI步态在站立阶段的足底压力分布。建立无CMI和有CMI的受试者三维模型。将实验研究得到的地面反作用力应用于FE足模型不同阶段的步态周期。在步态周期的所有阶段,使用CMI可以降低峰值接触压力。此外,特别是在步态周期的中间和末端站时,前脚的摩擦应力减少。CMI重新分配足底压力,并倾向于减少步态周期站立阶段的摩擦应力。有限元分析可以更好地理解传统方法难以计算的不同参数。有限元分析简化了步态周期不同阶段无CMI和有CMI的各种情况的研究。
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2022 14th Biomedical Engineering International Conference (BMEiCON)
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