Pub Date : 2016-11-08DOI: 10.5455/BCP.20130127023102
H. Hamurcu, A. Çayköylü, Eda Peksen, M. Ozturk, Neslihan Sevil
ABSTRACTDespite the limited evidence to support the combination of antipsychotics in treatment resistant schizophrenia in the literature, this situation is common in clinical practice. Treatment guidelines recommend monotherapy for schizophrenia primarily. In this article, a chronic schizophrenic case whose treatment is changed from combination of clozapine with aripiprazole to clozapine monotherapy and whose positive symptoms decreased with the decrease of clozapine doses 900 mg/day to 625 mg/day is reported.
{"title":"A Case of Chronic Schizophrenia Who were Switched from Combined Treatment to Monotherapy and Achieved a Decrease in Positive Symptoms after Lowering the Clozapine Dose","authors":"H. Hamurcu, A. Çayköylü, Eda Peksen, M. Ozturk, Neslihan Sevil","doi":"10.5455/BCP.20130127023102","DOIUrl":"https://doi.org/10.5455/BCP.20130127023102","url":null,"abstract":"ABSTRACTDespite the limited evidence to support the combination of antipsychotics in treatment resistant schizophrenia in the literature, this situation is common in clinical practice. Treatment guidelines recommend monotherapy for schizophrenia primarily. In this article, a chronic schizophrenic case whose treatment is changed from combination of clozapine with aripiprazole to clozapine monotherapy and whose positive symptoms decreased with the decrease of clozapine doses 900 mg/day to 625 mg/day is reported.","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77344969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-11-08DOI: 10.5455/BCP.20151223093022
Handan Özek Erkuran, B. Çakaloz, Özlem Önen, A. Kutlu
ABSTRACTAttention Deficit and Hyperactivity Disorder (ADHD) is among the most commonly encountered neurodevelopmental disorders in childhood with its reported worldwide prevalance as 5%. Among the recommended treatment regimens as stimulants, the most frequently advised ones are methylphenidate (MPH) preparates. Among long acting MPH preparates, the form that contains an osmotic release oral system (MPH-OROS) is frequently used in clinical practice. Studies about risks, causes and outcomes regarding high dose MPH intake and effects of high dose MPH preparates in humans are limited. This article presents the clinical picture of a 12 year old boy who attempted suicide by ingesting 15 tablets of 36- mg MPH OROS. Exposure to an overdose of MPH-OROS exhibited acute sympathomimetic toxicity but no life-threatening symptoms in this patient. This case report might suggest that higher doses of MPH-OROS could be tolerated well under fine clinical observation and management; although more larger scale studies in thi...
{"title":"Suicide Attempt with High Dose Long Acting Methylphenidate Ingestion: A Case Presentation","authors":"Handan Özek Erkuran, B. Çakaloz, Özlem Önen, A. Kutlu","doi":"10.5455/BCP.20151223093022","DOIUrl":"https://doi.org/10.5455/BCP.20151223093022","url":null,"abstract":"ABSTRACTAttention Deficit and Hyperactivity Disorder (ADHD) is among the most commonly encountered neurodevelopmental disorders in childhood with its reported worldwide prevalance as 5%. Among the recommended treatment regimens as stimulants, the most frequently advised ones are methylphenidate (MPH) preparates. Among long acting MPH preparates, the form that contains an osmotic release oral system (MPH-OROS) is frequently used in clinical practice. Studies about risks, causes and outcomes regarding high dose MPH intake and effects of high dose MPH preparates in humans are limited. This article presents the clinical picture of a 12 year old boy who attempted suicide by ingesting 15 tablets of 36- mg MPH OROS. Exposure to an overdose of MPH-OROS exhibited acute sympathomimetic toxicity but no life-threatening symptoms in this patient. This case report might suggest that higher doses of MPH-OROS could be tolerated well under fine clinical observation and management; although more larger scale studies in thi...","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84079228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-11-08DOI: 10.5455/BCP.20151003063454
S. Aldemir, M. Acar, Z. Ocak, E. Dalbudak, M. R. Yiğitoğlu, E. Gunduz
ABSTRACTObjective: Obsessive-compulsive disorder (OCD) is a frequent neuropsychiatric disorder, in which genetic factors play important causative roles. We investigated the roles of the (-1019 C/G) promoter region polymorphism of 5-HTR1A and the G861C coding region polymorphism of 5-HTR1B genes in susceptibility to OCD in a Turkish population.Methods: Two single nucleotide polymorphisms, 5-HTR1A (rs6296) and 5-HTR1B (rs6295) genes were genotyped in 76 OCD patients and 57 healthy controls that were unrelated, using PCR-RFLP method.Results: We did not observe any difference in the genotype distributions of rs6296 and rs6295 between the OCD patient and control groups.Conclusions: As far as we know, our study is the first to establish the association of genetic variants 5-HTR1A (rs6296) and 5-HTR1B (rs6295) with OCD in a Turkish population. Based on our results, the relationship between polymorphisms of 5-HTR1A (rs6296) and 5-HTR1B (rs6295) with OCD do not seem.
{"title":"Association of 5-HT1A and 5-HT1B Gene Polymorphisms with Obsessive-Compulsive Disorder in a Turkish Population","authors":"S. Aldemir, M. Acar, Z. Ocak, E. Dalbudak, M. R. Yiğitoğlu, E. Gunduz","doi":"10.5455/BCP.20151003063454","DOIUrl":"https://doi.org/10.5455/BCP.20151003063454","url":null,"abstract":"ABSTRACTObjective: Obsessive-compulsive disorder (OCD) is a frequent neuropsychiatric disorder, in which genetic factors play important causative roles. We investigated the roles of the (-1019 C/G) promoter region polymorphism of 5-HTR1A and the G861C coding region polymorphism of 5-HTR1B genes in susceptibility to OCD in a Turkish population.Methods: Two single nucleotide polymorphisms, 5-HTR1A (rs6296) and 5-HTR1B (rs6295) genes were genotyped in 76 OCD patients and 57 healthy controls that were unrelated, using PCR-RFLP method.Results: We did not observe any difference in the genotype distributions of rs6296 and rs6295 between the OCD patient and control groups.Conclusions: As far as we know, our study is the first to establish the association of genetic variants 5-HTR1A (rs6296) and 5-HTR1B (rs6295) with OCD in a Turkish population. Based on our results, the relationship between polymorphisms of 5-HTR1A (rs6296) and 5-HTR1B (rs6295) with OCD do not seem.","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89653881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-11-08DOI: 10.5455/BCP.20160322093750
G. Sevinçer, E. Ince, Ibrahim Taymur, N. Konuk
Objective: The aim of this study was to examine frequency of night eating syndrome and its correlates with depression, anxiety, impulsivity and problematic eating behaviors in a university sample f...
目的:本研究的目的是研究夜间进食综合征的频率及其与抑郁、焦虑、冲动和问题饮食行为的关系。
{"title":"Night Eating Syndrome Frequency in University Students: Association with Impulsivity, Depression, and Anxiety","authors":"G. Sevinçer, E. Ince, Ibrahim Taymur, N. Konuk","doi":"10.5455/BCP.20160322093750","DOIUrl":"https://doi.org/10.5455/BCP.20160322093750","url":null,"abstract":"Objective: The aim of this study was to examine frequency of night eating syndrome and its correlates with depression, anxiety, impulsivity and problematic eating behaviors in a university sample f...","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87138280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-11-08DOI: 10.5455/BCP.20160109124021
Ş. Eray, H. Uçar, Assoc. Prof. Ayse Pinar Vural
Diplopia is a condition that involves seeing double and impairs quality of life. Acute diplopia can be seen with some general medical drugs and psychotropic drugs. Selective serotonin reuptake inhibitors (SSRIs) are widely prescribed to treat a variety of psychiatric disorders. Sertraline is a relatively selective serotonin reuptake inhibitor with some dopamine reuptake inhibitor activity. This paper reports development of diplopia, a rare adverse effect of SSRI, in a 14 years old patient with major depressive disorder following use of sertraline. Clinicians should keep in mind that diplopia may occur with sertraline treatment.
{"title":"Sertraline-Induced Diplopia","authors":"Ş. Eray, H. Uçar, Assoc. Prof. Ayse Pinar Vural","doi":"10.5455/BCP.20160109124021","DOIUrl":"https://doi.org/10.5455/BCP.20160109124021","url":null,"abstract":"Diplopia is a condition that involves seeing double and impairs quality of life. Acute diplopia can be seen with some general medical drugs and psychotropic drugs. Selective serotonin reuptake inhibitors (SSRIs) are widely prescribed to treat a variety of psychiatric disorders. Sertraline is a relatively selective serotonin reuptake \u0000inhibitor with some dopamine reuptake inhibitor activity. This paper reports development of diplopia, a rare adverse effect of SSRI, in a 14 years old patient with major depressive disorder following use of sertraline. Clinicians should keep in mind that diplopia may occur with sertraline treatment.","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82750680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-11-08DOI: 10.5455/BCP.20151205113132
C. Evren, E. Dalbudak, Ö. Aydemir, Ertuğrul Köroğlu, B. Evren, S. Ozen, K. Coskun
Objective: The National Stressful Events Survey for Posttraumatic Stress Disorder (PTSD)-Short Scale (NSESSS-PTSD) allows dimensional self-rating assessment of PTSD according to the DSM-5. The aim of the present study was to evaluate psychometric properties of this scale as Turkish PTSD-Short Scale (PTSD-SS) in a sample of undergraduate students in Turkey. Method: Participants included 415 university students, among which 351 (84.8%) reported trauma and thus were included in the analysis. Participants were evaluated with the PTSD-SS and the PTSD Checklist Civilian (PCL-C) version. Results: Turkish version of the PTSD-SS was found to be psychometrically sound PTSD screening measure with high convergent validity when compared with PCL-C (r=0.79) and having a Cronbach’s ? of 0.87. In addition, a single component accounted for 49.94% of total variance for PTSD-SS. The PTSD-SS had sensitivity and specificity scores of 0.91 and 0.77, respectively, when using the optimal cut-off score of 24. Additionally, the PTSD-SS showed good discriminant validity as it significantly differentiated students with high risk of PTSD from those with low risk of PTSD. Conclusion: These findings supported the Turkish PTSD-SS as reliable and valid PTSD screening instrument with a unidimensional scale construct.
{"title":"Psychometric Properties of the Turkish PTSD-Short Scale in a Sample of Undergraduate Students","authors":"C. Evren, E. Dalbudak, Ö. Aydemir, Ertuğrul Köroğlu, B. Evren, S. Ozen, K. Coskun","doi":"10.5455/BCP.20151205113132","DOIUrl":"https://doi.org/10.5455/BCP.20151205113132","url":null,"abstract":"Objective: The National Stressful Events Survey for Posttraumatic Stress Disorder (PTSD)-Short Scale (NSESSS-PTSD) allows dimensional self-rating assessment of PTSD according to the DSM-5. The aim of the present study was to evaluate psychometric properties of this scale as Turkish PTSD-Short Scale (PTSD-SS) in a sample of undergraduate students in Turkey. \u0000Method: Participants included 415 university students, among which 351 (84.8%) reported trauma and thus were included in the analysis. Participants were evaluated with the PTSD-SS and the PTSD Checklist Civilian (PCL-C) version. \u0000Results: Turkish version of the PTSD-SS was found to be psychometrically sound PTSD screening measure with high convergent validity when compared with PCL-C (r=0.79) and having a Cronbach’s ? of 0.87. In addition, a single component accounted for 49.94% of total variance for PTSD-SS. The PTSD-SS had sensitivity and specificity scores of 0.91 and 0.77, respectively, when using the optimal cut-off score of 24. Additionally, the PTSD-SS showed good discriminant validity as it significantly differentiated students with high risk of PTSD from those with low risk of PTSD. \u0000Conclusion: These findings supported the Turkish PTSD-SS as reliable and valid PTSD screening instrument with a unidimensional scale construct.","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78235740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-11-08DOI: 10.5455/BCP.20151016123639
C. Sengul, M. Erdal, C. Sengul, Özlem İzci Ay, Ahmet Buber, H. Alacam, M. Ay, H. Herken
Association of the Neuropeptide Y LEU7PRO rs16139 and NEUREXIN 3 rs760288 polymorphisms with alcohol dependence Objective: Alcoholism is associated with genetic variants of genes related to alcohol metabolizing enzymes, dopaminergic, gamma-aminobutyric acidergic, glutamatergic, opioid, cholinergic, and serotonergic systems. Neurpeptide Y system and Neurexins were shown to be associated with alcohol dependence. Recent studies identified new genetic polymorphisms related to endogenous cannabinoid system, neuropetide Y and neurexin. In the present study, we aimed to investigate the association of Neurpeptide Y LEU7PRO rs16139 and neurexin 3 gene rs760288 polymorphisms with alcohol dependence in patients with alcohol dependence and healthy control subjects. Methods: 123 patients who were diagnosed with alcohol dependence according to the DSM-IV criteria and 159 healthy volunteers were included in the study. Blood samples were used to investigate polymorphisms. The genotyping of the neurexin 3 gene rs760288 and the neuropetide Y gene Leu7Pro rs16139 polymorphisms was performed using TaqMan SNP Genotyping Assays Real-Time PCR System. Results: Of the 2 genetic polymorphisms investigated in the present study, we detected association between and neurexin 3 gene rs760288 polymorphisms with alcohol dependence. Conclusions: Neurexin gene polymorphisms might be an important factor in development of alcohol addiction.
{"title":"Association of the Neuropeptide Y LEU7PRO rs16139 and NEUREXIN 3 rs760288 Polymorphisms with Alcohol Dependence","authors":"C. Sengul, M. Erdal, C. Sengul, Özlem İzci Ay, Ahmet Buber, H. Alacam, M. Ay, H. Herken","doi":"10.5455/BCP.20151016123639","DOIUrl":"https://doi.org/10.5455/BCP.20151016123639","url":null,"abstract":"Association of the Neuropeptide Y LEU7PRO rs16139 and NEUREXIN 3 rs760288 polymorphisms with alcohol dependence Objective: Alcoholism is associated with genetic variants of genes related to alcohol metabolizing enzymes, dopaminergic, gamma-aminobutyric acidergic, glutamatergic, opioid, cholinergic, and serotonergic systems. Neurpeptide Y system and Neurexins were shown to be associated with alcohol dependence. Recent studies identified new genetic polymorphisms related to endogenous cannabinoid system, neuropetide Y and neurexin. In the present study, we aimed to investigate the association of Neurpeptide Y LEU7PRO rs16139 and neurexin 3 gene rs760288 polymorphisms with alcohol dependence in patients with alcohol dependence and healthy control subjects. Methods: 123 patients who were diagnosed with alcohol dependence according to the DSM-IV criteria and 159 healthy volunteers were included in the study. Blood samples were used to investigate polymorphisms. The genotyping of the neurexin 3 gene rs760288 and the neuropetide Y gene Leu7Pro rs16139 polymorphisms was performed using TaqMan SNP Genotyping Assays Real-Time PCR System. Results: Of the 2 genetic polymorphisms investigated in the present study, we detected association between and neurexin 3 gene rs760288 polymorphisms with alcohol dependence. Conclusions: Neurexin gene polymorphisms might be an important factor in development of alcohol addiction.","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87713752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-11-08DOI: 10.5455/BCP.20150813023217
M. Güneş, S. Demir, M. Bulut, M. Kaya, A. Atlı, A. Ibiloğlu, H. Yüksel
ABSTRACTThe partial agonist aripiprazole is a novel atypical antipsychotic with a relatively safer side effect profile. Acute unilateral myopia is a very rare condition that is commonly associated with drug use. Here, we present a woman diagnosed with obsessive-compulsive disorder (OCD) and major depressive disorder (MDD) who have been treated for two years in our clinic. She was on fluoxetine (Prozac) 80 mg/day when adding aripiprazole (Abilify) 10 mg/day as an augmentation agent has triggered unilateral myopia. After cessation of aripirazole her myopia has disappeared. Psychiatrists should keep in mind that unilateral myopia as a side effect may develop after combining aripiprazole with fluoxetine in patients with OCD and MDD.
{"title":"Acute Unilateral Myopia Induced by Add-On Aripiprazole: A Case Report","authors":"M. Güneş, S. Demir, M. Bulut, M. Kaya, A. Atlı, A. Ibiloğlu, H. Yüksel","doi":"10.5455/BCP.20150813023217","DOIUrl":"https://doi.org/10.5455/BCP.20150813023217","url":null,"abstract":"ABSTRACTThe partial agonist aripiprazole is a novel atypical antipsychotic with a relatively safer side effect profile. Acute unilateral myopia is a very rare condition that is commonly associated with drug use. Here, we present a woman diagnosed with obsessive-compulsive disorder (OCD) and major depressive disorder (MDD) who have been treated for two years in our clinic. She was on fluoxetine (Prozac) 80 mg/day when adding aripiprazole (Abilify) 10 mg/day as an augmentation agent has triggered unilateral myopia. After cessation of aripirazole her myopia has disappeared. Psychiatrists should keep in mind that unilateral myopia as a side effect may develop after combining aripiprazole with fluoxetine in patients with OCD and MDD.","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5455/BCP.20150813023217","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72450530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-11-08DOI: 10.5455/BCP.20151221100426
B. E. Mergen, H. Arslan, Ebru Arslan, H. Mergen, Sibel Turgut, I. Bernstein
ABSTRACTIntroduction: The Quick Inventory of Depressive Symptomatology Adolescent Version QIDS-A17-SR has never been used before as an instrument measuring major depressive disorder symptomatology ...
摘要简介:抑郁症症状快速量表青少年版QIDS-A17-SR从未被用作衡量抑郁症症状的工具。
{"title":"Turkish validity & reliability of the quick inventory of depressive symptomatology adolescent version (QIDS-A17-SR) in comparison with the beck depression inventory-II among late adolescents -","authors":"B. E. Mergen, H. Arslan, Ebru Arslan, H. Mergen, Sibel Turgut, I. Bernstein","doi":"10.5455/BCP.20151221100426","DOIUrl":"https://doi.org/10.5455/BCP.20151221100426","url":null,"abstract":"ABSTRACTIntroduction: The Quick Inventory of Depressive Symptomatology Adolescent Version QIDS-A17-SR has never been used before as an instrument measuring major depressive disorder symptomatology ...","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77948770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-11-08DOI: 10.5455/BCP.20151003060610
Semanur Deniz, M. Sancar, B. Okuyan, P. Ata, O. Ozakpinar, A. Talas, T. Gunes, M. Çalışkan, F. Izzettin
Objective: The aim of this study is to determine relationship of cytochrome P-450 2C19 (CYP2C19) enzymes polymorphism, side effects, and medication adherence in patients who have been diagnosed wit...
{"title":"Determination of CYP2C19 polymorphism, side effects, and medication adherence in patients who have utilized selective serotonin reuptake inhibitors -","authors":"Semanur Deniz, M. Sancar, B. Okuyan, P. Ata, O. Ozakpinar, A. Talas, T. Gunes, M. Çalışkan, F. Izzettin","doi":"10.5455/BCP.20151003060610","DOIUrl":"https://doi.org/10.5455/BCP.20151003060610","url":null,"abstract":"Objective: The aim of this study is to determine relationship of cytochrome P-450 2C19 (CYP2C19) enzymes polymorphism, side effects, and medication adherence in patients who have been diagnosed wit...","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90548409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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