Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology最新文献

{"title":"Thyroxin Levels Associated with Current Suicide Attempts: A Case Control and Follow-Up Study","authors":"H. Ozcan, A. Yucel, O. Atıs, N. Yucel, A. Bilen, M. Emet, S. T. A. Gur","doi":"10.5455/BCP.20160217101946","DOIUrl":"https://doi.org/10.5455/BCP.20160217101946","url":null,"abstract":"ABSTRACTObjective: Suicide is a complex behavior concerning a number of psychological, biological, social and cultural factors. It is also an important public issue, as well as one of the leading causes of death. We aimed to examine the relationship between suicide attempt and thyroid hormones in suicide attempters and healthy controls and aimed to clarify whether any of the thyroid hormone levels may have predicted current or future suicide attempts.Method: This study comprised 358 participants (115 suicide attempters, 243 controls). Thyroid hormone levels including free T3, free T4, and TSH of all participants were explored. For predicting future suicide attempts using our hospital database and the database of the Republic of Turkey Social Security Institution, via International Classification of Diseases (ICD) diagnostic codes related to suicide data of future suicide attempts of the study participants were collected. Participants were people without previous history of any thyroid disorder or chronic ...","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86537705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Online Game Addiction in a Sample from Turkey: Development and Validation of the Turkish Version of Game Addiction Scale","authors":"Erkan Baysak, F. Kaya, Ilker Dalgar, S. Candansayar","doi":"10.5455/BCP.20150502073016","DOIUrl":"https://doi.org/10.5455/BCP.20150502073016","url":null,"abstract":"Objective: Online game addiction also referred to as internet gaming disorder, a clinical condition that is not well-established, is not listed in psychiatric classification systems due to lack of adequate studies but expected to be added to the manual in near future. In Turkey neither a scale nor a study is present to evaluate online game addiction/ addicts. We aimed to evaluate the reliability and validity of “The Game Addiction Scale” that was developed by Lemmens in 2009 as an instrument to assess online game addiction in an online game players sample in Turkey and examine the game addiction levels in these players. Methods: For this purpose 726 “Travian” (a massively multiplayer online game) players were evaluated with the Young’s Internet Addiction Test and the Lemmens’s Game Addiction Scale to find out their game addiction levels. Individual properties of the participants reflecting their internet use and gaming habits were also examined. The study was performed using SurveyMonkey within three months between March 1 and May 31, 2013. Results: Both 21-item (Cronbach’s α=0.96) and 7-item versions (Cronbach’s α=0.88) of the Game Addiction Scale were found to be valid and reliable. Also using the monothetic format 11.1% of the participants was found to be online game addicts. Conclusion: Our findings indicates that there is a considerably high percentage of game addiction within this online gamers sample compared to other countries. Further studies with online gamers and general population are needed to see the whole picture in Turkey.","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76543364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Course and Management of Drug-Induced Catatonia and Paranoid Behavior in an Adolescent","authors":"Parna Prajapati, D. Fabius, B. Pradhan","doi":"10.5455/BCP.20151217105437","DOIUrl":"https://doi.org/10.5455/BCP.20151217105437","url":null,"abstract":"ABSTRACTA 19-year-old Hispanic male with past psychiatric history of illicit drug use was brought by his mother to the emergency room of a tertiary care hospital with altered mental status. According to patient's mother his paranoid symptoms consisted of increased suspiciousness towards his friends and other family members, but were not to the extent for him to seek out any medical help. Clinical course and management of this patient, who later progressed to full blown catatonia, is described in this report. Patient had paradoxical disinhibition when treated with benzodiazepine, limiting treatment options. Patient's mother would not consent for ECT treatment after which Olanzapine was selected to manage his catatonic symptoms. This patient's preexisting paranoid ideations and catatonia were stabilized successfully with a few days of olanzapine with significant decrease in Bush-Francis Catatonia Score. Initial catatonia score of 14 points at baseline decreased to 3 points after 20 days of inpatient managem...","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79457108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attention Deficit Hyperactivity Disorder Treatment Practice in Turkey","authors":"O. Oner, H. Türkçapar, F. Isli, H. Karadağ, A. Akbulat, A. Basci, M. Aksoy, Cem Seckin, A. Alkan","doi":"10.5455/BCP.20151202103706","DOIUrl":"https://doi.org/10.5455/BCP.20151202103706","url":null,"abstract":"ABSTRACTObjective: To determine the factors associated with type of ADHD prescription and re-admission of the cases to the outpatient clinics between January-July 2013.Method: The Ministry of Health prescription database, which included prescriber, region, age and gender data and contained almost 20% of IMS data.Results: A total of 73,189 prescription were prescribed to a total of 41,341 (30,014 males; 72.7%) patients. 38645 (93.5%) of the patients were between 6 and 18 years of age. The most frequently prescribed drug was OROS methylphenidate (MPH, 59.7%) followed by IR MPH, atomoxetine and combination of drugs. There were several regional differences in prescription practice. Treatment choice changed significantly with age and gender. Rate of repeated prescription was highest among 6–18 year-old male subjects receiving combination treatment.Conclusions: ADHD treatment choice seemed to be heavily influenced by official regulations. Age, gender and drug of choice were important factors associated with tre...","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78663273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship Between Impulsivity and Plasma Uric Acid Levels in Patients with Substance Use Disorders","authors":"Serdar Nurmedov, Yelda İbadi, O. Noyan, Onat Yilmaz, S. Kesebir, N. Dilbaz, S. Kose","doi":"10.5455/BCP.20160222092414","DOIUrl":"https://doi.org/10.5455/BCP.20160222092414","url":null,"abstract":"Objective: Impulsivity is an important neurobiological process that contributes to individual differences in substance use disorder vulnerability. Uric acid has been mentioned to be telated to some...","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75119997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors affecting burden of psychopharmacological medication in patients with autism spectrum disorder: the importance of early diagnosis -","authors":"Şahin Bodur, C. Taşkıran, Yetiş Işıldar, Burcu Ersoz Alan, M. Çetinkaya, H. Kara, M. Şahin, S. Turgut","doi":"10.5455/BCP.20151230063042","DOIUrl":"https://doi.org/10.5455/BCP.20151230063042","url":null,"abstract":"ABSTRACTObjective: The aim of the present study is to specify the frequency in psychopharmacological medication use in children with autism spectrum disorder (ASD) and determine their age range at diagnosis.Methods: Five hundred and twenty three children with ASD who applied to Dr. Sami Ulus Maternity and Children Research and Training Hospital between 2010–2015 were reviewed retrospectively. Data has been obtained from computerized hospital information system. Individuals with the diagnosis of Autism (F84.0), Atypical Autism (F84.1) and Pervasive Developmental Disorder Not Other Specified (F84.9) were screened.Results: Psychotropic medication was recommended to 28.5% of the 523 children and adolescents diagnosed with ASD. Antipsychotics were the most common drugs of choice among psychotropic medications. The mean age at diagnosis of patients taking psychotropic medication was significantly higher than that of the patients who were not taking psychotropic medication (t=-3.064; p<0.01). The rate of psychot...","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84202763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychobiotics: The Potential Therapeutic Promise of Microbes in Psychiatry","authors":"Assoc. Prof. Gokben Hizli Sayar, M. Cetin","doi":"10.5455/BCP.20160531111208","DOIUrl":"https://doi.org/10.5455/BCP.20160531111208","url":null,"abstract":"The recognition of the importance of human microbiome for health and disease is a relatively recent issue. Studies suggest that the microbiome may contribute to the regulation of multiple neurochemical pathways that interconnect the gastrointestinal tract and other organs with the central nervous system. The microorganisms play a vital role in the immunological development of the host. Therefore, a selection between beneficial and harmful microbes is needed, and this vital role is guided by the immune system of the host. Probiotic therapy is the application of potentially beneficial microorganisms to support the balance of beneficial and harmful microbiota in our body system. The probiotic microorganisms not only compete with the pathogens of the host but also improve the immunological state of the host. As they colonize in the human intestine, they intricately involve with different systems of the body. Organisms used as probiotics are bacteria that exist naturally in the gut and are most frequently of the Lactobacillus, Bifidobacterium, Enterococcus, and Pediococcus species. The concept of modulating the microbiome is a novel and promising idea in various areas of medicine. “Vaginal seeding” is one of the most popular issues in the press, related to modulation of the microbiome. The term “vaginal seeding” describes the use of a gauze swab to transfer maternal vaginal fluid, and hence vaginal microbiota, on to an infant born by caesarean section. The composition of the early microbiota of infants is heavily influenced by mode of delivery. In infants born by caesarean section, the microbiota resembles that of maternal skin, while in vaginally born infants it is similar to that of the maternal vagina. These early differences in the microbiota have been suggested to determine susceptibility to some common diseases. In theory, vaginal seeding might rebuild the microbiota of infants born by caesarean section to a more “natural” state and decrease the risk of disease. Strong evidence supports a therapeutic role for probiotics in the treatment of inflammatory bowel disease, irritable bowel syndrome, atopic dermatitis, and arthritis. Probiotics have immunomodulatory, hypocholesterolemic, antihypertensive, and anti-allergic properties. They are proclaimed to lighten postmenopausal symptoms and have an effect of protection toward lung emphysema. While probiotics have been suggested as an adjuvant therapy for depression, our knowledge is limited about the potency of probiotic treatments to modulate CNS function.","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81971898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"beta-adrenergic Receptor Blocker Use for Traumatic Memory Reconsolidation in Posttraumatic Stress Disorder","authors":"S. Kose, M. Cetin","doi":"10.5455/BCP.20160927054221","DOIUrl":"https://doi.org/10.5455/BCP.20160927054221","url":null,"abstract":"","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75010904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Massive creatine kinase elevation during antipsychotic drug treatment with olanzapine and quetiapine","authors":"H. Ersen, F. Maner","doi":"10.5455/BCP.20151219072041","DOIUrl":"https://doi.org/10.5455/BCP.20151219072041","url":null,"abstract":"","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78843307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Propolis as a Complex Compound May Contain Many Active Ingredients Like Caffeic Acid Phenethyl Ester (CAPE)","authors":"M. A. Gulec, O. Akyol, S. Akyol","doi":"10.5455/BCP.20151006014845","DOIUrl":"https://doi.org/10.5455/BCP.20151006014845","url":null,"abstract":"We have read with great interest the article “Propolis induced mania with psychotic features: A case report” b y O z c a n e t a l . i n B u l l e t i n o f C l i n i c a l Psychopharmacology. The authors reported that high dose of propolis may have been the triggering factor of the manic symptoms with psychotic features. We would like to add some valuable information for both propolis and its active component, caffeic acid phenethyl ester (CAPE) (Figure 1) to explain why such type of symptoms might occur after propolis ingestion. For a better understanding of the cellular mechanisms of these potential psychiatric side effects, the authors should have mentioned the ingredients of propolis mixture, which have different physical, chemical, and functional properties. Propolis has been used in folkloric medicine for","PeriodicalId":17852,"journal":{"name":"Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83610436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}