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Technical tips and tricks for complex biplanar high tibial osteotomies 复杂双平面胫骨高位截骨术的技术技巧。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-09-29 DOI: 10.1002/ksa.70083
Tyler M. Hauer, Romed P. Vieider, David Wasserstein, Matthieu Ollivier, Volker Musahl

Purpose

While traditional high tibial osteotomy (HTO) techniques primarily address malalignment in the coronal plane, the significance of sagittal plane alignment, particularly the posterior tibial slope (PTS), is not to be overlooked in the setting of cruciate ligament insufficiency. Combined deformities involving both the coronal plane and the sagittal plane are less common and present unique surgical challenges. This narrative review summarizes the literature and introduces tips and tricks for managing complex biplanar deformities through a case-based discussion of different techniques.

Methods

This narrative review includes preoperative planning, surgical techniques, clinical outcomes and illustrative clinical cases detailing surgical rationale and technical nuances in the correction of biplanar proximal tibial deformities. Emphasis is placed on the importance of accurate assessment and correction of biplanar deformities to optimize patient outcomes. Four representative technique presentations are included: (1) Hybrid HTO with a posterior opening wedge (POW) and anterior closing wedge (ACW), (2) asymmetrical medial closing wedge (MCW) HTO, (3) medial opening wedge (MOW) HTO with an anterolateral hinge and (4) a double HTO with both an infratuberosity ACW and high MOW.

Conclusion

Biplanar HTO is a knee-preserving surgical option for a small cohort of patients with complex knee deformities involving both the coronal and sagittal planes. Precise preoperative planning and meticulous surgical execution are essential to address these biplanar malalignments effectively. This narrative review serves as a guide for orthopaedic surgeons, highlighting key considerations when planning biplanar HTO and serves as a practical guide for complex cases.

Level of Evidence

Level V.

目的:虽然传统的胫骨高位截骨术(HTO)主要解决冠状面对齐不良的问题,但在十字韧带功能不全的情况下,矢状面对齐,特别是胫骨后坡(PTS)的意义不容忽视。同时累及冠状面和矢状面的合并畸形不太常见,并提出了独特的手术挑战。这篇叙述性的综述总结了文献,并通过不同技术的案例讨论介绍了管理复杂的双平面畸形的技巧和技巧。方法:本文叙述回顾包括术前计划、手术技术、临床结果和说明性临床病例,详细介绍了矫正双平面胫骨近端畸形的手术原理和技术细节。重点放在准确评估和矫正双面畸形的重要性,以优化患者的结果。四种有代表性的技术包括:(1)混合HTO与后开口楔形(POW)和前闭合楔形(ACW),(2)不对称内侧闭合楔形(MCW) HTO,(3)内侧开口楔形(MOW) HTO与前外侧铰链,(4)双重HTO与下厚壁ACW和高MOW。结论:双平面HTO是一小部分累及冠状面和矢状面复杂膝关节畸形患者的保膝手术选择。精确的术前计划和细致的手术执行对于有效地解决这些双面错位至关重要。这篇叙述性综述为骨科医生提供了指南,强调了规划双平面HTO时的关键考虑因素,并为复杂病例提供了实用指南。证据等级:V级。
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引用次数: 0
The effectiveness of knee bracing in non-operative soft tissue and degenerative knee injuries: A systematic review 膝关节支具在非手术软组织和退行性膝关节损伤中的有效性:系统综述。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-09-29 DOI: 10.1002/ksa.70080
Marc Daniel Bouchard, Justin Gilbert, Michelle Cruickshank, Colin Kruse, Prushoth Vivekanantha, James Yan, Vickas Khanna

Purpose

Soft tissue and degenerative knee injuries, including anterior/posterior cruciate ligament (ACL/PCL) injuries, medial knee osteoarthritis (MKOA), and patellofemoral osteoarthritis (PFOA), are common causes of pain and functional decline. Knee bracing is often used as part of non-operative treatment, but its clinical effectiveness remains uncertain. This systematic review aimed to evaluate the role of bracing in improving pain, function, and preventing surgical conversion in adults with non-operatively managed knee injuries.

Methods

A systematic review was conducted following PRISMA guidelines. Embase, Ovid MEDLINE, and Ovid Emcare were searched from inception to March 2025. Studies were included if they reported clinical outcomes of knee bracing in adults with soft tissue or degenerative knee injuries treated non-operatively. Studies focused on biomechanics, prophylaxis, surgery, or paediatric populations were excluded. Data were synthesised narratively with weighted summary statistics.

Results

Seventeen studies (706 patients) were included: six on ACL injuries, three PCL, three MKOA, and five PFOA. MKOA studies showed pooled improvements of +14.6 in KOOS Pain and −1.9 in VAS (SDs 1.0 and 0.5). ACL studies reported a pooled Lysholm gain of +11.8 (SD = 4.3), while PCL outcomes showed large single-study improvements (KOOS Pain +31.0, IKDC + 30.0). WOMAC scores improved in MKOA (−13.7) but declined in PFOA (−6.4). Failure (surgical conversion) was reported in 13 studies, with the highest rates in PCL (16.4%) and ACL (10.6%), and the lowest in MKOA (0%) and PFOA (4.0%). Complications were infrequently reported; skin irritation was the most common adverse event.

Conclusion

Knee bracing demonstrated the most consistent pain and functional improvements in degenerative and PCL injuries. In contrast, outcomes in ACL injuries were more variable and associated with higher failure rates, underscoring the need for injury-specific bracing strategies. These findings emphasise the importance of patient selection, brace design, and early intervention, and support the need for higher-quality studies to guide non-operative management strategies.

Level of Evidence

Level IV.

目的:软组织和退行性膝关节损伤,包括前/后交叉韧带(ACL/PCL)损伤,膝关节内侧骨关节炎(MKOA)和髌股骨关节炎(PFOA),是疼痛和功能下降的常见原因。膝关节支具常作为非手术治疗的一部分,但其临床效果尚不确定。本系统综述旨在评估支具在改善成人非手术处理膝关节损伤的疼痛、功能和预防手术转化中的作用。方法:按照PRISMA指南进行系统评价。Embase、Ovid MEDLINE和Ovid Emcare从创建到2025年3月被检索。如果研究报告了非手术治疗的成人软组织或退行性膝关节损伤的膝关节支具的临床结果,则纳入研究。研究集中在生物力学、预防、外科或儿科人群被排除在外。数据采用加权汇总统计进行叙述性综合。结果:纳入17项研究(706例患者):6例ACL损伤,3例PCL, 3例MKOA, 5例PFOA。MKOA研究显示kos疼痛改善14.6,VAS改善-1.9 (SDs 1.0和0.5)。ACL研究报告综合Lysholm增益为+11.8 (SD = 4.3),而PCL结果显示单项研究有较大改善(oos Pain +31.0, IKDC + 30.0)。WOMAC评分在MKOA(-13.7)中有所改善,但在PFOA(-6.4)中有所下降。13项研究报告了手术转换失败,其中PCL(16.4%)和ACL(10.6%)的失败率最高,MKOA(0%)和PFOA(4.0%)的失败率最低。并发症很少报道;皮肤刺激是最常见的不良反应。结论:膝关节支具在退行性损伤和PCL损伤中表现出最一致的疼痛和功能改善。相比之下,前交叉韧带损伤的结果变化更大,与更高的失败率相关,强调了针对特定损伤的支具策略的必要性。这些发现强调了患者选择、支具设计和早期干预的重要性,并支持需要更高质量的研究来指导非手术治疗策略。证据等级:四级。
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引用次数: 0
High survival rates and patient satisfaction 12 years after medial open wedge high tibial osteotomy surgery: A prospective cohort study 内侧开楔形HTO手术后12年的高生存率和患者满意度:一项前瞻性队列研究。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-09-23 DOI: 10.1002/ksa.70071
Marc-Daniel Ahrend, Daniel Petzold, Tina Histing, Christoph Ihle, Steffen Schröter, Moritz Herbst

Purpose

Medial open wedge high tibial osteotomy (HTO) can delay knee arthroplasty (KA) in patients with medial compartment varus knee osteoarthritis (OA). However, prospectively collected long-term outcomes and survival rates are limited. The purpose of this study was to assess the survival rate and the outcome following HTO.

Methods

In this prospective cohort study with initially 120 knees from 112 patients treated from 2008 to 2011 with an HTO, 95 knees from 88 patients (age: 47.0 ± 7.6 years; female: n = 28) were followed-up. The minimum follow-up was 12 years or an earlier conversion to KA. The 5-, 10- and 12-year survival rates were calculated. The Lysholm and IKDC scores were assessed preoperatively and 1.5, 6 and 12 years postoperatively.

Results

At the last follow-up (12.9 ± 0.8,12.0–15.1 years), 67.4% (n = 64) had no conversion to KA. 31 knees (32.6%; 2 unicompartmental KA, 29 total KA) were converted to a KA on average 7.3 ± 3.3 (1.5–13.0) years after the HTO. The 5-, 10- and 12-year survival rates were 88.2%, 76.3% and 69.7%. Knees without conversion to KA had significantly higher scores at the last follow-up compared to preoperatively: The Lysholm score increased from 60.4 ± 21.1 (14.0–91.0) preoperatively to 89.1 ± 12.5 (39.0–100.0), 86.5 ± 13.8 (39.0–100.0) and 82.6 ± 18.3 (30.0–100.0). The IKDC score also increased from 51.8 ± 16.6 (15.0–93.0) preoperatively to 77.7 ± 14.8 (21.0–100.0), 70.9 ± 15.3 (26.0–98.0) and 72.5 ± 18.1 (14.0–95.0) at the corresponding postoperative time points 1.5, 6 and 12-years.

Conclusion

HTO to treat varus medial OA showed good long-term outcomes. Most patients can expect no conversion to KA for more than twelve years and a higher subjective knee function than preoperatively.

Level of Evidence

Level IV.

目的:内侧开楔形胫骨高位截骨术(HTO)可以延缓内侧室内翻膝骨性关节炎(OA)患者的膝关节置换术(KA)。然而,前瞻性收集的长期结果和生存率有限。本研究的目的是评估HTO后的生存率和预后。方法:在这项前瞻性队列研究中,对2008年至2011年接受HTO治疗的112例患者的120个膝关节,88例患者(年龄:47.0±7.6岁,女性:n = 28)的95个膝关节进行了随访。最小随访时间为12年或更早。计算5年、10年和12年生存率。术前、术后1.5年、6年和12年分别评估Lysholm和IKDC评分。结果:末次随访(12.9±0.8(12.0 ~ 15.1年))时,67.4% (n = 64)患者未转化为KA。术后平均7.3±3.3(1.5 ~ 13.0)年,31个膝关节(32.6%;单室KA 2例,总KA 29例)转化为KA。5年、10年和12年生存率分别为88.2%、76.3%和69.7%。与术前相比,未转换为KA的膝关节在最后一次随访时得分明显更高:Lysholm评分从术前的60.4±21.1(14.0-91.0)增加到89.1±12.5(39.0-100.0),86.5±13.8(39.0-100.0)和82.6±18.3(30.0-100.0)。术后1.5、6、12年相应时间点IKDC评分由术前51.8±16.6(15.0 ~ 93.0)上升至77.7±14.8(21.0 ~ 100.0)、70.9±15.3(26.0 ~ 98.0)、72.5±18.1(14.0 ~ 95.0)。结论:HTO治疗内翻性OA远期疗效良好。大多数患者在12年以上的时间内不会转化为KA,并且主观膝关节功能比术前更高。证据等级:四级。
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引用次数: 0
Anterior cruciate ligament injury incidence in male and female soccer players: A longitudinal study over six consecutive seasons 男女足球运动员前交叉韧带损伤发生率:一项连续六个赛季的纵向研究。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-09-22 DOI: 10.1002/ksa.70046
Alfred Ferré-Aniorte, Ignasi Bolibar, Ramón Cugat, Eduard Alentorn-Geli

Purpose

The aim of this study was to describe the anterior cruciate ligament (ACL) injury incidence differences depending on sex and age-related categories in a large cohort of soccer players over six consecutive seasons.

Methods

This study was designed as a retrospective descriptive epidemiological study. All soccer players in a specific geographical area who sustained an ACL injury across six consecutive seasons were included in this analysis. ACL injury incidence was calculated by sex and age-related category as a percentage of all registered soccer players in the region. Additionally, soccer participation evolution, ACL injury incidence evolution, and monthly ACL injury distribution were studied. Group, seasonal, and monthly differences were analysed using chi-square tests.

Results

Between the 2016–2017 and the 2021–2022 seasons, 3381 ACL injuries were registered from a total of 782,856 player-seasons. ACL injury incidence was 0.43%. Female soccer players showed 2.79 times higher injury incidence than male players, with overall rates of 1.06% in females and 0.38% in males (p < 0.001). However, female players only showed higher ACL injury incidence than males in age groups older than 14 years. ACL injury incidence increased over the six seasons studied only in the male group. October and January were the months with the highest number of ACL injuries, with no significant differences in monthly distribution between sexes.

Conclusions

Female soccer players showed higher ACL injury incidence than males, particularly in age groups older than 14 years. October and January were identified as the months with the highest injury incidences regardless of sex. Additionally, a rising injury incidence was observed in male players, a trend not seen in females.

Level of Evidence

Level III, retrospective comparative study.

目的:本研究的目的是描述前交叉韧带(ACL)损伤发生率的差异,这取决于性别和年龄相关的类别,在一个连续六个赛季的大队列足球运动员。方法:采用回顾性描述性流行病学研究。所有在特定地理区域连续六个赛季遭受前交叉韧带损伤的足球运动员都包括在这项分析中。前交叉韧带损伤发生率按性别和年龄相关类别计算,占该地区所有注册足球运动员的百分比。此外,研究了足球参与演变、前交叉韧带损伤发生率演变和每月前交叉韧带损伤分布。使用卡方检验分析组、季节和月差异。结果:2016-2017赛季至2021-2022赛季,共有782,856名球员赛季中发生了3381例ACL损伤。前交叉韧带损伤发生率为0.43%。女性足球运动员的ACL损伤发生率是男性运动员的2.79倍,女性的总体发生率为1.06%,男性为0.38% (p)。结论:女性足球运动员的ACL损伤发生率高于男性,特别是在14岁以上年龄组。10月和1月被确定为不分性别的伤害发生率最高的月份。此外,在男性球员中观察到受伤发生率的上升,而在女性球员中没有看到这种趋势。证据等级:III级,回顾性比较研究。
{"title":"Anterior cruciate ligament injury incidence in male and female soccer players: A longitudinal study over six consecutive seasons","authors":"Alfred Ferré-Aniorte,&nbsp;Ignasi Bolibar,&nbsp;Ramón Cugat,&nbsp;Eduard Alentorn-Geli","doi":"10.1002/ksa.70046","DOIUrl":"10.1002/ksa.70046","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>The aim of this study was to describe the anterior cruciate ligament (ACL) injury incidence differences depending on sex and age-related categories in a large cohort of soccer players over six consecutive seasons.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study was designed as a retrospective descriptive epidemiological study. All soccer players in a specific geographical area who sustained an ACL injury across six consecutive seasons were included in this analysis. ACL injury incidence was calculated by sex and age-related category as a percentage of all registered soccer players in the region. Additionally, soccer participation evolution, ACL injury incidence evolution, and monthly ACL injury distribution were studied. Group, seasonal, and monthly differences were analysed using chi-square tests.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Between the 2016–2017 and the 2021–2022 seasons, 3381 ACL injuries were registered from a total of 782,856 player-seasons. ACL injury incidence was 0.43%. Female soccer players showed 2.79 times higher injury incidence than male players, with overall rates of 1.06% in females and 0.38% in males (<i>p</i> &lt; 0.001). However, female players only showed higher ACL injury incidence than males in age groups older than 14 years. ACL injury incidence increased over the six seasons studied only in the male group. October and January were the months with the highest number of ACL injuries, with no significant differences in monthly distribution between sexes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Female soccer players showed higher ACL injury incidence than males, particularly in age groups older than 14 years. October and January were identified as the months with the highest injury incidences regardless of sex. Additionally, a rising injury incidence was observed in male players, a trend not seen in females.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level III, retrospective comparative study.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17880,"journal":{"name":"Knee Surgery, Sports Traumatology, Arthroscopy","volume":"33 12","pages":"4426-4434"},"PeriodicalIF":5.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://esskajournals.onlinelibrary.wiley.com/doi/epdf/10.1002/ksa.70046","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145116026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial intelligence and machine learning is successful in predicting clinical outcomes after hip arthroscopy for femoroacetabular impingement syndrome 人工智能和机器学习在预测股骨髋臼撞击综合征髋关节镜术后的临床结果方面取得了成功。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-09-22 DOI: 10.1002/ksa.70029
Katherine L. Esser, Bradley A. Lezak, Griff G. Gosnell, Heath P. Gould, Anil Ranawat, Benedict U. Nwachukwu, Michael Rizzo, Thomas Youm, Ayoosh Pareek

Purpose

To systematically review the current literature regarding the role of artificial intelligence and machine learning in predicting and optimising clinical outcomes following hip arthroscopy.

Methods

A systematic review of the PubMed, Cochrane, and EMBASE databases was completed in December 2024. Studies were included if they assessed the application of AI/ML to clinical outcomes of hip arthroscopy. Exclusion criteria were imaging-only studies, non-English publications, conference abstracts, review articles and meta-analyses. Extracted data included study characteristics, input features, algorithm types, sample sizes, and model performance. Descriptive statistical analysis was performed due to data heterogeneity.

Results

Sixteen studies met inclusion criteria, covering applications across prediction of intraoperative findings (n = 1), prediction of post-operative outcomes (n = 5), prediction of patient-reported outcomes (n = 7) and prediction of revision (n = 3). Input features commonly utilised included demographics, imaging data, preoperative patient-reported outcomes (PROs), and comorbidities. Supervised learning models were the most widely applied, including logistic regression, random forests, support vector machines (SVMs), and artificial neural networks (ANNs). Performance metrics demonstrated robust predictive ability, with AUC values ranging from 0.66 to 0.94 and accuracy rates exceeding 75% in most studies. Applications included predicting revision surgery risk, prolonged opioid use, postoperative satisfaction, and time to return to sport. Imaging-based algorithms, particularly leveraging MRI data, showed promise for surgical planning and diagnostic precision.

Conclusions

AI and ML show significant promise in enhancing outcome prediction and patient stratification in hip arthroscopy. Future research should prioritise the standardisation of datasets, external validation, and interpretability to facilitate clinical translation.

Level of Evidence

Level V.

目的:系统回顾人工智能和机器学习在预测和优化髋关节镜术后临床结果中的作用。方法:于2024年12月完成对PubMed、Cochrane和EMBASE数据库的系统评价。如果研究评估AI/ML在髋关节镜临床结果中的应用,则纳入研究。排除标准为影像学研究、非英文出版物、会议摘要、综述文章和荟萃分析。提取的数据包括研究特征、输入特征、算法类型、样本量和模型性能。由于数据异质性,进行描述性统计分析。结果:16项研究符合纳入标准,包括术中发现预测(n = 1)、术后结果预测(n = 5)、患者报告结果预测(n = 7)和翻修预测(n = 3)。通常使用的输入特征包括人口统计学、影像学数据、术前患者报告的结果(PROs)和合并症。监督学习模型的应用最为广泛,包括逻辑回归、随机森林、支持向量机(svm)和人工神经网络(ann)。性能指标显示出强大的预测能力,在大多数研究中,AUC值在0.66至0.94之间,准确率超过75%。应用包括预测翻修手术风险、延长阿片类药物使用、术后满意度和恢复运动的时间。基于成像的算法,特别是利用MRI数据,显示出手术计划和诊断精度的希望。结论:人工智能和机器学习在增强髋关节镜预后预测和患者分层方面具有重要的前景。未来的研究应优先考虑数据集的标准化、外部验证和可解释性,以促进临床翻译。证据等级:V级。
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引用次数: 0
Author Reply to ‘Letter to the Editor on “Knee hyperextension is not associated with anterior knee laxity, subjective knee function or revision surgery after anterior cruciate ligament reconstruction in children and adolescents”’ 作者回复关于“儿童和青少年前交叉韧带重建后,膝关节过伸与膝关节前松弛、主观膝关节功能或翻修手术无关”的致编辑的信。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-09-16 DOI: 10.1002/ksa.70062
Frida Hansson, Anders Stålman, Gunnar Edman, Per-Mats Janarv, Eva Bengtsson Moström, Riccardo Cristiani
<p>We would like to thank the authors for their thoughtful comments and interest in our study [<span>1, 6</span>]. We appreciate the opportunity to clarify certain aspects of our methodology. First, we would like to clarify that there are currently no universally accepted cut-off values for defining knee hyperextension in either adult or paediatric populations. The few studies that have explored the relationship between preoperative passive knee hyperextension and outcomes after anterior cruciate ligament (ACL) reconstruction (ACLR) have used a threshold of ≤−5°, but this cut-off was chosen arbitrarily and lacks formal validation [<span>2-4</span>]. We fully acknowledge that passive knee hyperextension is both age- and sex-dependent and is particularly prevalent among children and adolescents [<span>11</span>]. However, the objective of our study was specifically to investigate the influence of <i>physiological</i> knee hyperextension on outcomes following ACLR. As the authors correctly noted, 52.9% of the patients in our cohort were categorised as having knee hyperextension. This should not be interpreted as <i>pathological</i> hyperextension, given that all patients included had isolated ACL injuries, with no concomitant ligamentous damage. In addition, to address the limitations related to the definition of hyperextension, we conducted a subgroup analysis of patients with knee extension ≤−10°, which similarly showed no significant association with postoperative knee laxity outcomes. We appreciate the thoughtful suggestion to incorporate age- and sex-stratified analyses or to use receiver operating characteristic curve methods to define paediatric-specific thresholds. However, as outlined above, our study was designed to assess the potential impact of <i>physiological</i> knee hyperextension, and not to redefine or establish new cut-offs for pathological hyperextension in the paediatric population.</p><p>With regard to the lack of information on rotational laxity, we agree with the authors that the pivot-shift test is an important clinical assessment and has been associated with patient-reported outcomes, return to sport, and an increased risk of graft failure [<span>5, 8</span>]. While we acknowledge the absence of rotational laxity data as a limitation, it is important to note that the primary objective of our study was not to examine the relationship between pivot-shift grading and outcomes after ACLR. Rather, our focus was on assessing the association between preoperative passive knee hyperextension and postoperative outcomes. Biomechanical studies have demonstrated increased strain and tension on the ACL during passive knee hyperextension [<span>7, 9, 10</span>], which could theoretically translate into greater postoperative laxity or a higher risk of graft failure and revision ACLR. However, in our cohort, we did not observe any significant increase in anterior knee laxity at 6 months postoperatively, nor did we find a higher rate of revi
我们要感谢作者对我们研究的周到评论和兴趣[1,6]。我们感谢有机会澄清我们方法的某些方面。首先,我们想要澄清的是,目前在成人或儿童人群中没有普遍接受的定义膝关节过伸的临界值。少数研究探讨了术前被动膝关节过伸与前交叉韧带(ACL)重建(ACLR)后预后之间的关系,这些研究使用了≤- 5°的阈值,但这一临界值的选择是随意的,缺乏正式的验证[2-4]。我们充分认识到,被动膝关节过伸与年龄和性别有关,在儿童和青少年中尤为普遍。然而,我们研究的目的是专门研究生理性膝关节过伸对ACLR后预后的影响。正如作者正确指出的那样,我们队列中52.9%的患者被归类为膝关节过伸。考虑到所有患者都是孤立的前交叉韧带损伤,没有伴随的韧带损伤,这不应被解释为病理性过伸。此外,为了解决与超伸定义相关的局限性,我们对膝关节伸度≤- 10°的患者进行了亚组分析,同样显示与术后膝关节松弛结果无显著关联。我们很欣赏将年龄和性别分层分析或使用接受者工作特征曲线方法定义儿科特异性阈值的周到建议。然而,如上所述,我们的研究旨在评估生理性膝关节过伸的潜在影响,而不是重新定义或建立儿科人群病理性膝关节过伸的新界限。由于缺乏关于旋转松弛的信息,我们同意作者的观点,即枢轴移位试验是一项重要的临床评估,与患者报告的结果、恢复运动和移植物失败风险增加有关[5,8]。虽然我们承认缺乏旋转松弛度数据是一个局限性,但重要的是要注意,我们研究的主要目的不是检查轴心转移分级与ACLR后结果之间的关系。相反,我们的重点是评估术前被动膝关节过伸与术后结果之间的关系。生物力学研究表明,被动膝关节过伸时ACL的应变和张力增加[7,9,10],理论上这可能导致术后更大的松弛或移植物失败和翻修ACLR的风险增加。然而,在我们的队列中,我们没有观察到术后6个月前膝关节松弛的任何显著增加,也没有发现术前膝关节过伸患者术后5年的ACLR翻修率更高。我们再次感谢作者提供的宝贵意见,这些意见有助于不断完善这一重要主题。作者声明无利益冲突。本研究获得了卡罗林斯卡学院区域伦理委员会的伦理许可(日记号:2016/1613-31/2)。登记研究不要求同意参与。
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引用次数: 0
Instability after total knee arthroplasty: A systematic review and meta-analysis of treatment options and outcomes 全膝关节置换术后不稳定:治疗方案和结果的系统回顾和荟萃分析。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-09-12 DOI: 10.1002/ksa.70065
Lenka Stroobant, Amber Marvellie, Jani Windels, Hannes Vermue, Nele Arnout, Stefaan Van Onsem, Jan Victor
<div> <section> <h3> Purpose</h3> <p>Instability is a rising cause of revision total knee arthroplasty (rTKA), creating significant challenges for patients, surgeons and the healthcare system. This systematic review and meta-analysis aimed to evaluate the outcomes of conservative management, isolated polyethylene exchange (PE), and rTKA as treatments for post-TKA instability. The primary outcome was patient-reported outcome measures (PROMs), with secondary outcomes including reoperation rates, revision rates, and implant survival (Aim 1). Additionally, the study examined the effect of instability type on PROMs (Aim 2) and the impact of prosthesis constraint on PROMs (Aim 3).</p> </section> <section> <h3> Methods</h3> <p>A systematic search of studies published from 2000 to July 2024 was conducted. (1) Studies analysing the outcome of conservative treatment, isolated PE exchange or revision surgery for instability were included, reporting on PROMs, reoperations, revisions, and/or survival free from revision. PROMs included the Knee Society Score, both clinical (KSCS) and functional (KSFS). Revision was defined as the removal and replacing of the femoral and/or tibial component. A meta-analysis was only performed for revision surgery as treatment. (2) Instability was classified into flexion and extension instability. (3) Prosthetic constraints analysed included posterior stabilised (PS), condylar constrained knee (CCK), and rotating hinged knee (RHK).</p> </section> <section> <h3> Results</h3> <p>A total of 27 articles, involving 4269 knees, were included in the analysis: two studies on conservative management, 12 on isolated PE exchange, and 19 on revision surgeries. (1) Conservative treatment, primary physiotherapy, yielded inconsistent results. Isolated PE exchange showed poor outcomes, with recurrent instability and subsequent revision occurring in 6.5%–18.5% of cases. However, in carefully selected patients, outcomes comparable to rTKA were observed. Revision surgery showed a mean improvement of 32 points (95% confidence interval [CI], 20.5–43.5; <i>p</i> < 0.001) for KSKS and 24.3 points (95% CI, 17.2–31.4; <i>p</i> < 0.001) for KSFS. During follow-up, 5.3% (46/864) of the patients underwent a rerevision, with 41.3% attributed to instability. (2) Extension instability showed a trend toward better KSKS (<i>p</i> = 0.04) and KSFS scores (<i>p</i> = 0.03) than flexion instability, and (3) no evidence of superiority was found between different types of constraint in this study.</p> </section> <section> <h3> Conclusions</h3> <p>When guided by appropriate clinical indications, conservative management, isolated PE exchange, and
目的:不稳定性是翻修全膝关节置换术(rTKA)的一个上升原因,给患者、外科医生和医疗保健系统带来了重大挑战。本系统综述和荟萃分析旨在评估保守治疗、孤立聚乙烯交换(PE)和rTKA作为tka后不稳定治疗的结果。主要结果是患者报告的结果测量(PROMs),次要结果包括再手术率、翻修率和种植体存活率(Aim 1)。此外,本研究还研究了不稳定类型对PROMs的影响(Aim 2)和假体约束对PROMs的影响(Aim 3)。方法:系统检索2000年至2024年7月发表的相关研究。(1)研究分析了保守治疗、孤立PE置换或翻修手术治疗不稳定的结果,报告了PROMs、再手术、翻修和/或翻修后存活的情况。PROMs包括膝关节社会评分,包括临床(KSCS)和功能(KSFS)。翻修定义为股骨和/或胫骨假体的移除和置换。一项荟萃分析仅对翻修手术进行了治疗。(2)失稳分为屈曲失稳和伸展失稳。(3)假体约束分析包括后路稳定(PS)、髁约束膝关节(CCK)和旋转铰接膝关节(RHK)。结果:共纳入27篇文献,涉及4269个膝关节:2篇关于保守治疗的研究,12篇关于孤立性PE置换的研究,19篇关于翻修手术的研究。(1)保守治疗,即初级物理治疗,结果不一致。孤立PE置换的预后较差,6.5%-18.5%的病例会出现复发性不稳定和随后的翻修。然而,在精心挑选的患者中,观察到与rTKA相当的结果。翻修手术平均改善32分(95%可信区间[CI], 20.5-43.5; p)。结论:在适当的临床指征指导下,保守治疗、孤立PE置换和翻修手术可获得良好的tka后不稳定治疗结果。不稳定性仍然是矫正的主要原因,当屈伸间隙无法达到平衡时,需要更高的假体约束。证据等级:四级,系统评价。
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引用次数: 0
The use of injectable orthobiologics for knee osteoarthritis: A formal ESSKA-ORBIT consensus. Part 2—Cell-based therapy 使用可注射的骨科治疗膝骨关节炎:正式的ESSKA-ORBIT共识。第二部分:细胞疗法。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-09-09 DOI: 10.1002/ksa.70001
Laura de Girolamo, Giuseppe Filardo, Ferran Abat, Kristoffer Weisskirchner Barfod, Ricardo Bastos, Ramon Cugat, Michael Iosifidis, Baris Kocaoglu, Elizaveta Kon, Jeremy Magalon, Rodica Marinescu, Marko Ostojic, Mikel Sanchez, Thomas Tischer, Jasmin Bagge, Konrad Slynarski, Lucienne Vonk, Philippe Beaufils, Lior Laver, ESSKA-ORBIT Group
<div> <section> <h3> Purpose</h3> <p>This European Society of Sports Traumatology, Knee Surgery and Arthroscopy (ESSKA) formal consensus aims to provide evidence- and expert opinion-based recommendations for the use of point-of-care- and expanded-cell-based therapy (CBT) in the treatment of knee osteoarthritis (OA), focusing on indications, preparation, and administration.</p> </section> <section> <h3> Methods</h3> <p>A multidisciplinary group of 77 leading experts in musculoskeletal regenerative medicine from 22 European Countries formed a steering group, a rating group, and a reader group. The steering group developed 23 questions, originating from 27 statements. The statements were graded from A (high-level scientific evidence) to D (expert opinion). The question-statement sets were scored by the rating group from 1 to 9 according to the level of agreement. The document was then assessed for geographic adaptability by the reader group composed of representatives from ESSKA-affiliated societies.</p> </section> <section> <h3> Results</h3> <p>Overall, the statements received a mean score of 8.2 (standard deviation: 0.3) points out of a possible 9 and a median score of 8 (range: 6–9). Among the 27 statements, 9 were considered appropriate with strong agreement, and 18 were considered appropriate with relative agreement. Five statements received a recommendation level of A or B, and 22 were rated as C or D. In terms of geographic adaptability, 18 affiliated ESSKA Societies expressed support, two were opposed, and two abstained. CBT has demonstrated consistent clinical benefits, particularly in pain and function improvement up to 12 months, supporting its use for patients with Kellgren–Lawrence (KL) Grades 1–3 knee OA, with some benefits, though inferior, in selected KL Grade 4. However, due to limited high-quality studies and a lack of clear superiority over other injectables, CBT should be considered as a second-line treatment option.</p> </section> <section> <h3> Conclusions</h3> <p>The consensus document acknowledges ongoing debate about CBT's full effectiveness, though evidence suggests potential clinical benefits in pain relief and functional improvement. CBT are supported as a second-line injectable treatment for KL 1–3 knee OA 1–3, with some benefits shown in Grade 4 too. However, gaps remain in high-quality studies and treatment protocols. Nevertheless, evidence suggests that CBT may be seen as an alternative to traditional injectables like corticosteroids and hyaluronic acid, given the longer-lasting benefits, and could currently be consider
目的:欧洲运动创伤学、膝关节外科和关节镜学会(ESSKA)正式共识旨在提供基于证据和专家意见的建议,用于治疗膝关节骨性关节炎(OA),重点关注适应症、准备和给药。方法:由来自22个欧洲国家的77位肌肉骨骼再生医学的主要专家组成的多学科小组组成了一个指导小组、一个评级小组和一个读者小组。指导小组根据27项发言提出了23个问题。这些陈述的等级从A(高级科学证据)到D(专家意见)。问题陈述集由评分组根据同意程度从1到9打分。然后,由eska附属协会代表组成的读者小组对该文件的地理适应性进行了评估。结果:总体而言,这些陈述的平均得分为8.2分(标准差:0.3),满分为9分,中位数得分为8分(范围:6-9)。在27项声明中,9项被认为是适当的,并强烈同意,18项被认为是适当的,并相对同意。推荐等级为a或B的有5个,推荐等级为C或d的有22个。在地理适应性方面,18个附属学会表示支持,2个反对,2个弃权。CBT已显示出一致的临床益处,特别是在长达12个月的疼痛和功能改善方面,支持其用于Kellgren-Lawrence (KL) 1-3级膝关节OA患者,在选定的KL 4级患者中有一些益处,尽管效果较差。然而,由于高质量的研究有限,并且与其他注射剂相比缺乏明显的优势,CBT应被视为二线治疗选择。结论:尽管有证据表明CBT在缓解疼痛和功能改善方面有潜在的临床益处,但该共识文件承认关于CBT完全有效性的持续争论。CBT被支持作为KL 1-3膝关节OA 1-3的二线注射治疗,在4级患者中也显示出一些益处。然而,在高质量的研究和治疗方案方面仍然存在差距。然而,有证据表明,CBT可能被视为皮质类固醇和透明质酸等传统注射剂的替代品,鉴于其更持久的益处,目前可以在其他非手术治疗失败后考虑CBT。证据等级:一级。
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引用次数: 0
Lower baseline scores best predict achievement of the minimal clinically important difference after hip arthroscopy: A machine learning analysis from the Femoroacetabular Impingement RandomiSed Controlled Trial and embedded prospective cohort 较低的基线评分最好地预测髋关节镜术后最小临床重要差异的实现:来自股髋臼撞击随机对照试验和嵌入前瞻性队列的机器学习分析。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-09-09 DOI: 10.1002/ksa.70053
Prushoth Vivekanantha, Jeffrey Kay, Nicole Simunovic, Olufemi R. Ayeni, the FIRST Investigators

Purpose

This analysis evaluated whether logistic regression and machine learning models could predict achievement of the minimal clinically important difference (MCID) for the International Hip Outcome Tool (iHOT-12) and Hip Outcome Score (HOS) at 6 and 12 months following hip arthroscopy.

Methods

Data from the multicenter Femoroacetabular Impingement RandomiSed controlled Trial and its embedded prospective cohort were used. A total of 309 patients (mean ± SD age 34.0 ± 8.7 years, 37.7% female) were included. The MCID thresholds for iHOT-12 and HOS were calculated using a distribution-based method and were 9.0 and 13.0, respectively. Predictive models were trained with demographic, radiographic, and intraoperative variables using a 70:30 training-to-test data split. MCID achievement was defined as a change from preoperative to postoperative scores that surpassed the calculated threshold. Model discrimination was assessed using the area under the curve (AUC), and calibration was evaluated via slope, intercept, and Brier scores.

Results

Achievement rates were 83.3% at 6 months and 81.1% at 12 months for iHOT-12, and 64.3% at 6 months and 75% at 12 months for HOS. Logistic regression performed best at 12 months (AUC = 0.724) for iHOT-12 with poor calibration (slope = 2.19). AUCs for HOS ranged between 0.672–0.715 at 6 months and 0.665–0.699 at 12 months. Best calibration was achieved by Least Absolute Shrinkage and Selection Operator (slope = 1.270, intercept = –0.177) at 6 months and by logistic regression at 12 months (slope = 1.093, intercept = –0.079). Lower baseline patient-reported outcome measures (PROMs) were associated with MCID achievement in most models.

Conclusion

The most robust predictor of MCID achievement for both PROMs were lower baseline scores, and can be used as a prognostic variable for preoperative counselling. Model performance for predicting MCID was superior for HOS relative to iHOT-12. Machine learning models generally had comparable discrimination and calibration scores to traditional logistic regression models.

Level of Evidence

Level III.

目的:本分析评估了逻辑回归和机器学习模型是否可以预测国际髋关节结果工具(iHOT-12)和髋关节结果评分(HOS)在髋关节镜检查后6个月和12个月的最小临床重要差异(MCID)的实现。方法:采用多中心股髋臼撞击随机对照试验及其嵌入前瞻性队列的数据。共纳入309例患者(平均±SD年龄34.0±8.7岁,女性37.7%)。采用基于分布的方法计算iHOT-12和HOS的MCID阈值,分别为9.0和13.0。预测模型采用人口统计学、放射学和术中变量进行训练,训练与测试数据比例为70:30。MCID成就定义为术前到术后评分的变化超过计算阈值。使用曲线下面积(AUC)评估模型判别,通过斜率、截距和Brier评分评估模型校准。结果:iHOT-12组6个月和12个月的成功率分别为83.3%和81.1%;HOS组6个月和12个月的成功率分别为64.3%和75%。对于标度较差(斜率= 2.19)的iHOT-12, Logistic回归在12个月时表现最佳(AUC = 0.724)。居屋的auc介乎6个月时的0.672-0.715及12个月时的0.665-0.699。6个月时通过最小绝对收缩和选择算子(斜率= 1.270,截距= -0.177)和12个月时通过逻辑回归(斜率= 1.093,截距= -0.079)获得最佳校准。在大多数模型中,较低的基线患者报告的结果测量(PROMs)与MCID的实现相关。结论:较低的基线评分是两种PROMs患者MCID成就的最可靠预测指标,可作为术前咨询的预后变量。HOS预测MCID的模型性能优于iHOT-12。机器学习模型通常具有与传统逻辑回归模型相当的判别和校准分数。证据等级:三级。
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引用次数: 0
Kinematic alignment doesn't tell the whole story: It's time for kinetic alignment 运动学对齐并不能说明问题的全部:是时候进行动力学对齐了。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-09-09 DOI: 10.1002/ksa.70010
Umile Giuseppe Longo, Giovanni Spallone, Arianna Carnevale, Letizia Mancini, Emiliano Schena, Rocco Papalia, Michael Tobias Hirschmann

Kinematic alignment is increasingly adopted in total knee arthroplasty (TKA) as a patient-specific strategy to restore native joint anatomy. However, its reliance on static radiographic measurements may not adequately reflect real-world functional biomechanics. This editorial underscores the importance of complementing static assessment with kinetic principles. This emerging concept, referred to as kinetic alignment, integrates dynamic parameters such as the dynamic hip-knee-ankle angle, knee adduction moment, ground reaction forces, and muscle forces to better characterise in vivo joint loading. These kinetic variables provide critical insight into joint loading during real-life activities and may offer greater predictive value for implant performance and patient satisfaction. Continued emphasis on static alignment targets may overlook key elements of in vivo knee function. Incorporating kinetic data into preoperative planning could support more tailored surgical decisions, helping to mitigate risks related to malalignment, overloading, and suboptimal outcomes. The editorial advocates for expanding the concept of alignment beyond static geometry, including both motion and load, and encouraging the orthopaedic and biomechanical communities to adopt a more functional and individualised perspective in TKA planning.

在全膝关节置换术(TKA)中,越来越多地采用运动学对齐作为一种患者特有的策略来恢复原有的关节解剖。然而,它对静态放射测量的依赖可能不能充分反映现实世界的功能生物力学。这篇社论强调了用动力学原理补充静态评估的重要性。这个新兴的概念,被称为动态对齐,整合了动态参数,如动态髋关节-膝关节-踝关节角度,膝关节内收力矩,地面反作用力和肌肉力,以更好地表征体内关节负荷。这些动力学变量提供了对现实生活中关节负荷的关键洞察,并可能为植入物性能和患者满意度提供更大的预测价值。继续强调静态对齐目标可能会忽略体内膝关节功能的关键因素。将动力学数据纳入术前计划可以支持更有针对性的手术决策,有助于降低与不对准、超载和次优结果相关的风险。该社论主张将对齐概念扩展到静态几何之外,包括运动和负载,并鼓励骨科和生物力学团体在TKA规划中采用更功能和个性化的观点。
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引用次数: 0
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Knee Surgery, Sports Traumatology, Arthroscopy
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