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Freddie Fu Panther Symposium Expert Group 2024: Rehabilitation and return to sport after anterior cruciate ligament reconstruction Part 1: Early and intermediate phases of rehabilitation Freddie Fu Panther座谈会专家组2024:前交叉韧带重建后的康复和重返运动第1部分:早期和中期康复阶段。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-04 DOI: 10.1002/ksa.70115
Anja M. Wackerle, Andrew Sprague, Richard Joreitz, Eric H. Senorski, Stephen J. Rabuck, Bryson P. Lesniak, Eni Halilaj, Jonathan D. Hughes, Volker Musahl, James J. Irrgang, 2024 Panther Expert Group

Strategies for optimal rehabilitation after anterior cruciate ligament (ACL) reconstruction (ACLR) continue to evolve, as the incidence of contralateral ACL injuries and ACL failures varies widely in the literature, highlighting the need for optimising rehabilitation protocols. Early and intermediate rehabilitation build the crucial foundation on which later stages of rehabilitation can successfully be based, ideally leading to satisfactory outcomes and return to preinjury sports performance. However, guidelines for optimal pre- and postoperative rehabilitation management following ACLR remain conflicting, complicating evidence-based decision-making for rehabilitation following ACLR in clinical practice. Furthermore, a standardised rehabilitation protocol, adopted across different institutions, could enable more reliable comparisons of outcomes across studies focusing on surgical aspects, such as graft selection and fixation methods. An international, multidisciplinary group of experts was convened at the 2024 Freddie Fu Panther Sports Medicine Symposium to discuss and debate recent advances and future directions of rehabilitation and return to sport following ACLR. While this part of the series explores the preoperative and early to intermediate phases of rehabilitation, Part 2 highlights the complexity of return to sport and adjunct technologies after ACLR. Early recovery of knee extension, quadriceps function and early focus on movement quality are key components for achieving satisfactory outcomes after ACLR. This summary of key concepts aims to give an overview of recent evidence and current concepts of early and intermediate rehabilitation after ACLR from a multidisciplinary expert perspective and how it needs to be tailored to the individual based on graft type and patient demographics in clinical practice.

Level of Evidence

Level IV, expert opinion.

前交叉韧带(ACL)重建(ACLR)后的最佳康复策略不断发展,因为文献中对侧ACL损伤和ACL失败的发生率差异很大,突出了优化康复方案的必要性。早期和中期康复是后期康复成功的关键基础,理想情况下会导致令人满意的结果并恢复到损伤前的运动表现。然而,ACLR术前和术后最佳康复管理指南仍然存在冲突,这使得临床实践中ACLR术后康复的循证决策复杂化。此外,不同机构采用的标准化康复方案可以更可靠地比较外科方面的研究结果,如移植物选择和固定方法。在2024年Freddie Fu Panther运动医学研讨会上,召集了一个国际多学科专家组,讨论和辩论ACLR后康复和重返运动的最新进展和未来方向。虽然本系列的这一部分探讨了术前和早期到中期的康复阶段,但第2部分强调了ACLR后恢复运动和辅助技术的复杂性。早期恢复膝关节伸展、股四头肌功能和早期关注运动质量是ACLR术后获得满意结果的关键因素。这一关键概念的总结旨在从多学科专家的角度概述ACLR后早期和中期康复的最新证据和当前概念,以及在临床实践中如何根据移植物类型和患者人口统计学进行个性化定制。证据等级:四级,专家意见。
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引用次数: 0
Precision medicine in orthopaedics: A review of current technologies and future directions 骨科精准医学:当前技术和未来发展方向综述。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-01 DOI: 10.1002/ksa.70168
Patrick Sadoghi, Amir Koutp, Elmar Herbst, Giuseppe Milano, Volker Musahl, Michael T. Hirschmann
<div> <section> <h3> Purpose</h3> <p>To synthesise the paradigm shift towards precision medicine in orthopaedics, where individual anatomical, biomechanical, molecular and kinematic characteristics are integrated into clinical decision-making. Unlike traditional approaches applying uniform protocols, this review outlines how precision orthopaedics aims to tailor surgical techniques, implant selection, component positioning and rehabilitation strategies to the unique profile of each patient, thereby improving outcomes and predictability.</p> </section> <section> <h3> Methods</h3> <p>This narrative review synthesises current concepts and evidence supporting patient-specific care. The methods discussed encompass a wide range of technological and biological innovations, including advanced imaging, robotic-assisted surgery, artificial intelligence (AI), molecular diagnostics, functional assessment tools and personalised therapeutic platforms that are shaping modern orthopaedic practice across multiple subspecialties.</p> </section> <section> <h3> Results</h3> <p>In total knee arthroplasty, personalised alignment restores native joint lines, while robotic systems execute plans with submillimetre accuracy, reducing alignment outliers and potentially improving functional outcomes. In total hip arthroplasty, spinopelvic analysis mitigates instability risk, a critical factor for patients with spinal stiffness. Intraoperative technologies like robotics, patient-specific instruments and augmented reality improve the precision of implant placement and reduce radiation exposure in trauma. Beyond arthroplasty, AI accelerates early diagnosis of osteoarthritis, while molecular biomarkers (e.g., alpha-defensin) offer >95% accuracy in diagnosing periprosthetic joint infection. Finally, AI-guided digital platforms and motion tracking are used to deliver personalised rehabilitation protocols.</p> </section> <section> <h3> Conclusion</h3> <p>Precision medicine encompasses a wide range of powerful tools, many of which are already in clinical use. However, their full and effective integration requires continued research, long-term validation, cost-effectiveness analyses and interdisciplinary collaboration. The future of orthopaedics is anchored in delivering the right intervention for the right patient at the right time, guided by robust, individualised data and sound clinical judgement.</p> </section> <section> <h3> Level of Evidence</h3> <p>Level V.</p>
目的:综合骨科向精准医学的范式转变,将个体解剖、生物力学、分子和运动学特征整合到临床决策中。与采用统一方案的传统方法不同,本综述概述了精确骨科如何针对每个患者的独特情况量身定制手术技术、植入物选择、组件定位和康复策略,从而改善结果和可预测性。方法:这篇叙述性综述综合了当前支持患者特异性护理的概念和证据。讨论的方法涵盖了广泛的技术和生物创新,包括先进的成像,机器人辅助手术,人工智能(AI),分子诊断,功能评估工具和个性化治疗平台,这些正在塑造跨多个亚专科的现代骨科实践。结果:在全膝关节置换术中,个性化的关节对齐恢复了原有的关节线,而机器人系统以亚毫米的精度执行计划,减少了对齐异常值,并有可能改善功能结果。在全髋关节置换术中,脊柱骨盆分析降低了不稳定风险,这是脊柱僵硬患者的一个关键因素。术中技术,如机器人技术、患者专用仪器和增强现实技术,提高了植入物放置的精度,减少了创伤中的辐射暴露。除了关节置换术,人工智能还加速了骨关节炎的早期诊断,而分子生物标志物(如α -防御素)在诊断假体周围关节感染方面的准确率为95%左右。最后,使用人工智能引导的数字平台和运动跟踪来提供个性化的康复方案。结论:精准医学包含了广泛的强大工具,其中许多已经在临床使用。然而,它们的充分和有效的整合需要持续的研究、长期的验证、成本效益分析和跨学科的合作。骨科的未来是在可靠的、个性化的数据和合理的临床判断的指导下,在正确的时间为正确的病人提供正确的干预。证据等级:V级。
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引用次数: 0
Freddie Fu Panther Symposium Expert Group 2024: Rehabilitation and return to sport after anterior cruciate ligament reconstruction Part 2: Concepts and emerging technology in return to sport Freddie Fu Panther座谈会专家组2024:前交叉韧带重建后的康复和重返运动第2部分:重返运动的概念和新兴技术。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-31 DOI: 10.1002/ksa.70110
Anja M. Wackerle, Richard Joreitz, Andrew Sprague, Eric H. Senorski, Eni Halilaj, Stephen J. Rabuck, Bryson P. Lesniak, Jonathan D. Hughes, Volker Musahl, James J. Irrgang, 2024 Panther Expert Group

Anterior cruciate ligament reconstruction is frequently performed to allow athletes to return to their pre-injury levels of sports participation. A relatively low proportion of athletes successfully achieving this goal, and high rates of secondary injuries after clearance for return to sport highlight the need for optimised rehabilitation and return to sports protocols. A lack of evidence and general consensus on optimal return to sport milestones has caused substantial variability across currently applied concepts, emphasising the need for interdisciplinary approaches to bridge the gap between research findings and clinical application. This summary of key concepts aims to provide a comprehensive framework for optimising return to sport outcomes following anterior cruciate ligament reconstruction in athletes from a multidisciplinary expert perspective. An international, multidisciplinary group of experts was convened at the 2024 Freddie Fu Panther Sports Medicine Symposium to discuss and debate recent advances, future directions and emerging technological innovations of rehabilitation and return to sport following anterior cruciate ligament reconstruction. While Part 1 addressed recent evidence and strategies for early and intermediate phases of rehabilitation after anterior cruciate ligament reconstruction, Part 2 of this series explores the complexity of return to sport conceptualised as a continuum by evaluating key aspects such as functional testing, psychological readiness, and prevention of re-injury while also discussing emerging technologies that promise to enhance the future of rehabilitation and return to sports after anterior cruciate ligament reconstruction.

Level of Evidence

Level IV, expert opinion.

前交叉韧带重建经常进行,以使运动员恢复到他们受伤前的运动参与水平。成功实现这一目标的运动员比例相对较低,并且在恢复运动后继发损伤的比例很高,这突出了优化康复和恢复运动协议的必要性。缺乏证据和普遍共识的最佳回归运动里程碑导致了目前应用概念的巨大差异,强调需要跨学科的方法来弥合研究结果和临床应用之间的差距。这个关键概念的总结旨在从多学科专家的角度提供一个全面的框架,以优化运动员前交叉韧带重建后的运动结果。2024年Freddie Fu Panther运动医学研讨会召集了一个国际多学科专家组,讨论和辩论前交叉韧带重建后康复和重返运动的最新进展、未来方向和新兴技术创新。第一部分介绍了前交叉韧带重建后早期和中期康复的最新证据和策略,本系列的第2部分通过评估功能测试,心理准备,预防再次受伤,同时也讨论了新兴技术,这些技术有望增强前交叉韧带重建后的康复和重返运动。证据等级:四级(专家意见)。
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引用次数: 0
Compromised quadriceps and hamstring force control, not maximal strength, is associated with gait biomechanics at 9 months following anterior cruciate ligament reconstruction 前交叉韧带重建后9个月,四头肌和腘绳肌力量控制受损与步态生物力学有关,而不是最大力量。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-28 DOI: 10.1002/ksa.70129
Beyza Tayfur, Alexa K. Johnson, Riann M. Palmieri-Smith

Purpose

To understand the changes in muscle force control ability and its association to gait biomechanics following anterior cruciate ligament reconstruction (ACLR).

Methods

Twenty-five participants, 9 months following ACLR, performed isometric quadriceps (20%, 40% and 100% maximum voluntary isometric contraction [MVIC]) and hamstring (20% and 40% MVIC) contractions on an isokinetic dynamometer, tracing a target line. Torque variability using coefficient of variation, and complexity using sample entropy were calculated. Knee moments and knee flexion excursion were calculated from walking gait. Two-way mixed model analyses of variance were used for between-limb comparisons and Pearson's correlations to evaluate the associations between force variables and gait biomechanics.

Results

Quadriceps and hamstring torque variability changed depending on the limb and the effort level. Quadriceps variability was higher in the ACLR limb only at maximum effort (p = 0.039, Cohen's d = 0.437). Hamstring variability showed no differences at 40% but lower torque variability (p = 0.035, Cohen's d = −0.448) at 20%. Muscle force complexity was consistently higher in the ACLR limb compared to the noninjured limb, regardless of effort level. Additionally, as effort increased, muscle force became less complex in both limbs.

Quadriceps variability was negatively associated with knee moments (r = −0.410, p = 0.042, better force control = higher knee extension moments). Hamstring complexity was positively associated with knee flexion excursion (r = 0.417, p = 0.038). Maximal strength was not associated with any gait biomechanics.

Conclusions

Quadriceps and hamstring force control ability are altered and associated with gait biomechanics at 9 months post-ACLR. Rehabilitation should include exercises focused on force control to potentially help restore gait biomechanics.

Level of Evidence

Level IV.

目的:了解前交叉韧带重建(ACLR)术后肌力控制能力的变化及其与步态生物力学的关系。方法:25名参与者,ACLR后9个月,在等速测力仪上进行等速四头肌(20%,40%和100%最大自主等速收缩[MVIC])和腘绳肌(20%和40% MVIC)收缩,追踪目标线。用变异系数计算扭矩变异性,用样本熵计算复杂性。根据步行步态计算膝关节力矩和膝关节屈曲偏移量。采用双向混合模型方差分析进行肢体间比较和Pearson相关来评估力变量与步态生物力学之间的关联。结果:股四头肌和腘绳肌的扭矩可变性取决于肢体和力量水平。股四头肌变异性仅在最大努力时在ACLR肢体中较高(p = 0.039, Cohen’s d = 0.437)。腿筋变异性在40%时没有差异,但在20%时扭矩变异性较低(p = 0.035, Cohen’s d = -0.448)。无论努力程度如何,与未受伤肢体相比,ACLR肢体的肌肉力量复杂性始终较高。此外,随着努力的增加,四肢的肌肉力量变得不那么复杂。股四头肌可变性与膝关节力矩呈负相关(r = -0.410, p = 0.042,更好的力量控制=更高的膝关节伸展力矩)。腘绳肌复杂性与膝关节屈曲偏移呈正相关(r = 0.417, p = 0.038)。最大力量与任何步态生物力学无关。结论:在aclr后9个月,股四头肌和腘绳肌力量控制能力发生改变,并与步态生物力学有关。康复应包括集中力量控制的练习,以潜在地帮助恢复步态生物力学。证据等级:四级。
{"title":"Compromised quadriceps and hamstring force control, not maximal strength, is associated with gait biomechanics at 9 months following anterior cruciate ligament reconstruction","authors":"Beyza Tayfur,&nbsp;Alexa K. Johnson,&nbsp;Riann M. Palmieri-Smith","doi":"10.1002/ksa.70129","DOIUrl":"10.1002/ksa.70129","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>To understand the changes in muscle force control ability and its association to gait biomechanics following anterior cruciate ligament reconstruction (ACLR).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Twenty-five participants, 9 months following ACLR, performed isometric quadriceps (20%, 40% and 100% maximum voluntary isometric contraction [MVIC]) and hamstring (20% and 40% MVIC) contractions on an isokinetic dynamometer, tracing a target line. Torque variability using coefficient of variation, and complexity using sample entropy were calculated. Knee moments and knee flexion excursion were calculated from walking gait. Two-way mixed model analyses of variance were used for between-limb comparisons and Pearson's correlations to evaluate the associations between force variables and gait biomechanics.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Quadriceps and hamstring torque variability changed depending on the limb and the effort level. Quadriceps variability was higher in the ACLR limb only at maximum effort (<i>p</i> = 0.039, Cohen's <i>d</i> = 0.437). Hamstring variability showed no differences at 40% but lower torque variability (<i>p</i> = 0.035, Cohen's <i>d</i> = −0.448) at 20%. Muscle force complexity was consistently higher in the ACLR limb compared to the noninjured limb, regardless of effort level. Additionally, as effort increased, muscle force became less complex in both limbs.</p>\u0000 \u0000 <p>Quadriceps variability was negatively associated with knee moments (<i>r</i> = −0.410, <i>p</i> = 0.042, better force control = higher knee extension moments). Hamstring complexity was positively associated with knee flexion excursion (<i>r</i> = 0.417, <i>p</i> = 0.038). Maximal strength was not associated with any gait biomechanics.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Quadriceps and hamstring force control ability are altered and associated with gait biomechanics at 9 months post-ACLR. Rehabilitation should include exercises focused on force control to potentially help restore gait biomechanics.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level IV.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17880,"journal":{"name":"Knee Surgery, Sports Traumatology, Arthroscopy","volume":"33 12","pages":"4466-4474"},"PeriodicalIF":5.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://esskajournals.onlinelibrary.wiley.com/doi/epdf/10.1002/ksa.70129","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145380277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digital rehabilitation after anterior cruciate ligament reconstruction—A systematic review 前交叉韧带重建后手指康复的系统回顾。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-28 DOI: 10.1002/ksa.70141
Leonard Fricke, Wolf Petersen, Martin Häner, Amelie Klaumünzer, Thomas Tischer

Purpose

The aim of this systematic review was to analyze the implementation of digital rehabilitation in the rehabilitation of patients undergoing anterior cruciate ligament reconstruction (ACLR).

Methods

A systematic literature research was carried out on multiple platforms. Articles that fit our criteria were selected and analysed. We created a narrative synthesis of the extracted data, categorised by the type of digital application (sensor or no sensor), clinical characteristics and type of outcome. A formal meta-analysis was not planned as the studies were probably not homogeneous enough in terms of participants, interventions and outcomes to provide a meaningful summary.

Results

This systematic review analysed seven articles with 952 patients studying digital applications in rehabilitation⁠ after ACLR. Seven different digital applications were investigated, with three using sensors. The results showed that digital interventions were at least as effective as standard physiotherapy, with some studies showing even better outcomes in terms of Patient-Reported Outcome Measures (PROMs), muscle strength, and range of motion⁠. Patient engagement and better adherence to the rehabilitation plan was another positive finding. Importantly, no adverse events were reported in any of the studies⁠.

Conclusion

This systematic review highlights the potential of digital applications as valuable tools for rehabilitation after ACL reconstruction by enhancing patient adherence, engagement, and recovery outcomes.

Level of Evidence

N/A.

目的:本系统综述的目的是分析数字康复在前交叉韧带重建(ACLR)患者康复中的实施情况。方法:采用多平台系统文献研究。我们选择并分析了符合我们标准的文章。我们创建了提取数据的叙述性综合,根据数字应用类型(传感器或无传感器),临床特征和结果类型进行分类。由于这些研究在参与者、干预措施和结果方面可能不够均匀,无法提供有意义的总结,因此没有计划进行正式的荟萃分析。结果:本系统综述分析了7篇952例ACLR术后康复中数字应用的研究。研究人员调查了七种不同的数字应用,其中三种使用了传感器。结果表明,数字干预至少与标准物理治疗一样有效,一些研究显示,在患者报告的结果测量(PROMs)、肌肉力量和活动范围方面,结果甚至更好。患者参与和更好地遵守康复计划是另一个积极的发现。重要的是,在任何研究中均未报告不良事件。结论:本系统综述强调了数字应用作为ACL重建后康复的有价值工具的潜力,通过提高患者的依从性、参与度和恢复结果。证据级别:无。
{"title":"Digital rehabilitation after anterior cruciate ligament reconstruction—A systematic review","authors":"Leonard Fricke,&nbsp;Wolf Petersen,&nbsp;Martin Häner,&nbsp;Amelie Klaumünzer,&nbsp;Thomas Tischer","doi":"10.1002/ksa.70141","DOIUrl":"10.1002/ksa.70141","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>The aim of this systematic review was to analyze the implementation of digital rehabilitation in the rehabilitation of patients undergoing anterior cruciate ligament reconstruction (ACLR).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A systematic literature research was carried out on multiple platforms. Articles that fit our criteria were selected and analysed. We created a narrative synthesis of the extracted data, categorised by the type of digital application (sensor or no sensor), clinical characteristics and type of outcome. A formal meta-analysis was not planned as the studies were probably not homogeneous enough in terms of participants, interventions and outcomes to provide a meaningful summary.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>This systematic review analysed seven articles with 952 patients studying digital applications in rehabilitation⁠ after ACLR. Seven different digital applications were investigated, with three using sensors. The results showed that digital interventions were at least as effective as standard physiotherapy, with some studies showing even better outcomes in terms of Patient-Reported Outcome Measures (PROMs), muscle strength, and range of motion⁠. Patient engagement and better adherence to the rehabilitation plan was another positive finding. Importantly, no adverse events were reported in any of the studies⁠.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This systematic review highlights the potential of digital applications as valuable tools for rehabilitation after ACL reconstruction by enhancing patient adherence, engagement, and recovery outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>N/A.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17880,"journal":{"name":"Knee Surgery, Sports Traumatology, Arthroscopy","volume":"34 1","pages":"351-361"},"PeriodicalIF":5.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145380471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tobacco's toll: Comparable anterior cruciate ligament graft failure rates and inferior functional outcomes in smokers compared to non-smokers: A systematic review and meta-analysis 吸烟的危害:吸烟者与非吸烟者相比,前交叉韧带移植失败率和较差的功能结局:一项系统回顾和荟萃分析。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-28 DOI: 10.1002/ksa.70146
Jean-Paul S. Rinne, Roderick J. M. Vossen, Gaby V. ten Noever de Brauw, Jelle P. van der List, Roel J. H. Custers, Andrew D. Pearle, Hendrik A. Zuiderbaan

Purpose

Anterior cruciate ligament reconstruction (ACLR) is among the most performed orthopaedic procedures. Evaluating the effect of smoking on postoperative outcomes following ACLR could benefit many patients. This study investigated the impact of smoking on graft failure and functional outcomes following ACLR.

Methods

PubMed, MEDLINE, and Embase were searched up until March 9, 2025. The primary outcome was ACL graft failure after ACLR. Inclusion criteria were: age ≥18 years, ≥1-month follow-up (FU), ACL reconstruction, and articles in English. Exclusion criteria were: cadaveric studies, ACL repair, ≤5 participants, reviews, and case reports. Meta-analysis results were reported as odds ratios (ORs) and proportions with 95% confidence intervals (CIs).

Results

A total of 12 studies were included (92,208 patients) (mean FU: 42.8 ± 17.0 months; mean age: 35.9 ± 6 years; 6.8% smokers; 57.9% male). The quality of included studies was moderate, (MINORS score range: 9 to 21). In smoker's reoperation rate was 7.6% (FU 59.4 months). For non-smokers the reoperation rate was 5.2% (59.9 months FU). Three studies (2,823 patients) compared ACL graft failure rates, with similar pooled failure rates of 5.0% and 5.5% in smokers and non-smokers, respectively (OR 1.12 [95% CI: 0.38–3.29]). Four studies (1285 patients) compared postoperative IKDC scores with mean scores of 79.6 ± 10.3 in smokers and 84.0 ± 9.5 in non-smokers, respectively (OR 5.12 [95% CI: 3.59–6.65]). One study reported Tegner scores that were not different between smokers (5.0) and non-smokers (5.4).

Conclusion

This systematic review demonstrated that ACL graft failure and all-cause reoperation rates did not differ significantly between smokers and non-smokers. Nonetheless, non-smokers were significantly more likely to achieve superior functional outcomes following ACL reconstruction.

Level of Evidence

Level IV.

目的:前交叉韧带重建(ACLR)是最常用的骨科手术之一。评估吸烟对ACLR术后预后的影响可以使许多患者受益。本研究调查了吸烟对ACLR术后移植物衰竭和功能结局的影响。方法:检索至2025年3月9日的PubMed、MEDLINE和Embase。主要结局是ACLR后ACL移植失败。纳入标准为:年龄≥18岁,随访≥1个月,ACL重建,文章为英文。排除标准为:尸体研究、ACL修复、≤5名参与者、综述和病例报告。meta分析结果以比值比(OR)和95%置信区间(CI)的比例报告。结果:共纳入12项研究(92208例患者)(平均FU: 42.8±17.0个月;平均年龄:35.9±6岁;吸烟6.8%;男性57.9%)。纳入的研究质量一般(未成年人评分范围:9 - 21)。吸烟者再手术率为7.6%(术后59.4个月)。非吸烟者再手术率为5.2%(59.9个月FU)。三项研究(2,823例患者)比较了前交叉韧带移植失败率,吸烟者和非吸烟者的总失败率相似,分别为5.0%和5.5% (OR 1.12 [95% CI: 0.38-3.29])。四项研究(1285例患者)比较了术后IKDC评分,吸烟者和非吸烟者的平均评分分别为79.6±10.3和84.0±9.5 (OR 5.12 [95% CI: 3.59-6.65])。一项研究报告了吸烟者(5.0)和非吸烟者(5.4)之间的Tegner评分没有差异。结论:本系统综述表明,吸烟和不吸烟的前交叉韧带移植失败和全因再手术率无显著差异。尽管如此,非吸烟者更有可能在ACL重建后获得更好的功能结果。证据等级:四级。
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引用次数: 0
Effectiveness of digital health technologies in postoperative rehabilitation following anterior cruciate ligament reconstruction: A systematic review and meta-analysis 数字健康技术在前交叉韧带重建术后康复中的有效性:系统回顾和荟萃分析。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-28 DOI: 10.1002/ksa.70134
Qing Sun, Hang Yin, Liyuan Guan, Limin Cui

Purpose

To evaluate the effectiveness of digital health technology (DHT) in postoperative rehabilitation following anterior cruciate ligament reconstruction (ACLR) and to explore intervention characteristics influencing outcomes.

Methods

Seven databases (PubMed, Web of Science, Embase, Cochrane Library, SinoMed, CNKI and Wan Fang) were searched from inception to 15 March 2025 for randomized controlled trials on DHT (e.g., wearable devices, virtual reality, robotics) for ACLR rehabilitation. Outcomes included rehabilitation adherence, knee function, proprioception, muscle strength, walking ability and pain. Meta-analysis using a random effects model was conducted to determine the standardized mean difference (SMD) or mean difference (MD) with 95% confidence intervals (CIs).

Results

This review included 16 RCTs with a total of 1064 ACLR patients. The meta-analysis results indicated that DHT improved rehabilitation adherence (SMD = 0.29, 95% CI = 0.02–0.56, p = 0.04), pain (SMD = −0.79, 95% CI = −1.38 to −0.19, p = 0.009), proprioception (MD = −0.99, 95% CI = −1.47 to −0.50, p < 0.0001), muscle strength (extensor peak torque: MD = 11.43, 95% CI = 6.26–16.61, p < 0.0001; flexor peak torque: MD = 12.03, 95% CI = 6.54–17.52, p < 0.0001) and walking ability (MD = 0.41, 95% CI = 0.32–0.49, p < 0.00001). Subgroup analyses indicated that virtual reality-based DHT improved knee function (MD = 3.88, 95% CI = 0.95–6.81, p = 0.010). Short-term interventions (<3 months) showed greater efficacy in functional recovery (MD = 3.57, 95% CI = 0.93–6.20, p = 0.008).

Conclusion

DHT is a feasible and effective approach for post-ACLR rehabilitation. Our findings demonstrate that DHT enhances adherence, improves knee function and alleviates pain, and restores muscle strength, proprioception and walking ability. These results support the integration of DHT into standardized rehabilitation protocols for ACLR patients.

Level of Evidence

Level IV.

目的:评价数字健康技术(DHT)在前交叉韧带重建术(ACLR)术后康复中的应用效果,探讨影响康复效果的干预措施特点。方法:检索PubMed、Web of Science、Embase、Cochrane Library、SinoMed、CNKI、万方等7个数据库,检索自成立至2025年3月15日DHT(如可穿戴设备、虚拟现实、机器人)用于ACLR康复的随机对照试验。结果包括康复依从性、膝关节功能、本体感觉、肌肉力量、行走能力和疼痛。采用随机效应模型进行meta分析,以95%置信区间(ci)确定标准化平均差(SMD)或平均差(MD)。结果:本综述纳入16项随机对照试验,共1064例ACLR患者。meta分析结果显示DHT改善了康复依从性(SMD = 0.29, 95% CI = 0.02 ~ 0.56, p = 0.04)、疼痛(SMD = -0.79, 95% CI = -1.38 ~ -0.19, p = 0.009)、本体感觉(MD = -0.99, 95% CI = -1.47 ~ -0.50, p)。结论DHT是一种可行、有效的aclr后康复方法。我们的研究结果表明,DHT可以增强依从性,改善膝关节功能,减轻疼痛,恢复肌肉力量,本体感觉和行走能力。这些结果支持将DHT纳入ACLR患者的标准化康复方案。证据等级:四级。
{"title":"Effectiveness of digital health technologies in postoperative rehabilitation following anterior cruciate ligament reconstruction: A systematic review and meta-analysis","authors":"Qing Sun,&nbsp;Hang Yin,&nbsp;Liyuan Guan,&nbsp;Limin Cui","doi":"10.1002/ksa.70134","DOIUrl":"10.1002/ksa.70134","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>To evaluate the effectiveness of digital health technology (DHT) in postoperative rehabilitation following anterior cruciate ligament reconstruction (ACLR) and to explore intervention characteristics influencing outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Seven databases (PubMed, Web of Science, Embase, Cochrane Library, SinoMed, CNKI and Wan Fang) were searched from inception to 15 March 2025 for randomized controlled trials on DHT (e.g., wearable devices, virtual reality, robotics) for ACLR rehabilitation. Outcomes included rehabilitation adherence, knee function, proprioception, muscle strength, walking ability and pain. Meta-analysis using a random effects model was conducted to determine the standardized mean difference (SMD) or mean difference (MD) with 95% confidence intervals (CIs).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>This review included 16 RCTs with a total of 1064 ACLR patients. The meta-analysis results indicated that DHT improved rehabilitation adherence (SMD = 0.29, 95% CI = 0.02–0.56, <i>p</i> = 0.04), pain (SMD = −0.79, 95% CI = −1.38 to −0.19, <i>p</i> = 0.009), proprioception (MD = −0.99, 95% CI = −1.47 to −0.50, <i>p</i> &lt; 0.0001), muscle strength (extensor peak torque: MD = 11.43, 95% CI = 6.26–16.61, <i>p</i> &lt; 0.0001; flexor peak torque: MD = 12.03, 95% CI = 6.54–17.52, <i>p</i> &lt; 0.0001) and walking ability (MD = 0.41, 95% CI = 0.32–0.49, <i>p</i> &lt; 0.00001). Subgroup analyses indicated that virtual reality-based DHT improved knee function (MD = 3.88, 95% CI = 0.95–6.81, <i>p</i> = 0.010). Short-term interventions (&lt;3 months) showed greater efficacy in functional recovery (MD = 3.57, 95% CI = 0.93–6.20, <i>p</i> = 0.008).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>DHT is a feasible and effective approach for post-ACLR rehabilitation. Our findings demonstrate that DHT enhances adherence, improves knee function and alleviates pain, and restores muscle strength, proprioception and walking ability. These results support the integration of DHT into standardized rehabilitation protocols for ACLR patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level IV.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17880,"journal":{"name":"Knee Surgery, Sports Traumatology, Arthroscopy","volume":"34 2","pages":"709-723"},"PeriodicalIF":5.0,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145380494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Objective clinical tests to inform decision-making prior to return to sport in athletes with shoulder instability: A scoping review 客观临床试验为肩部不稳定运动员重返运动前的决策提供信息:一项范围综述。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-27 DOI: 10.1002/ksa.70107
Johan Högberg, Aleksandra Królikowska, Robert Prill, Alex Fails, Adam Popchak, Eric Hamrin Senorski

Purpose

This review systematically maps the existing research on objective return to sport criteria for shoulder injuries, with a focus on clinical tests that inform decision-making.

Methods

A scoping review was performed. The following databases were searched from inception up to July 2025: Cochrane Library, Embase, Medline, PEDRo, Cinahl and AMED. All studies, regardless of design, which assessed any kind of shoulder function with regard to return to sport decision-making in individuals participating in sports and presented with a shoulder injury were included. The result was qualitatively presented in free text, tables and figures.

Results

Eleven studies were identified that reported objective shoulder tests prior to return to sport in athletes after shoulder instability surgery. The tests evaluated various parameters, including range of motion, muscular strength, muscular endurance, power, plyometrics, movement quality and trunk control. The passing rates of isokinetic shoulder strength tests ranged from 40% to 70%, the isometric shoulder strength tests from 28% to 100%, for shoulder endurance tests from 70% to 81% and shoulder performance tests from 29% to 100%. These assessments were conducted within a time frame of 4–21 months following surgery. The rate of subsequent shoulder instability or re-dislocation ranged from 5% to 10% after returning to sport.

Conclusions

Passing rates for objective shoulder tests, including muscular strength and endurance, as well as performance tests, varied widely, with re-dislocation rates between 5% and 10% after returning to sport. However, the predominance of case series limits the ability to draw definitive conclusions about the effectiveness of these tests in reducing the risk of subsequent shoulder instability.

Level of Evidence

Level IV, scoping review of level III.

目的:本综述系统地绘制了关于肩部损伤客观回归运动标准的现有研究,重点是为决策提供信息的临床试验。方法:进行范围审查。检索了从成立到2025年7月的以下数据库:Cochrane Library、Embase、Medline、PEDRo、Cinahl和AMED。所有的研究,无论设计如何,评估任何类型的肩部功能与参与运动并出现肩部损伤的个人重返运动决策有关的研究都被纳入其中。结果以自由文本、表格和图形定性呈现。结果:11项研究报告了肩部不稳定手术后运动员重返运动前的客观肩部检查。测试评估了各种参数,包括运动范围、肌肉力量、肌肉耐力、力量、增强训练、运动质量和躯干控制。等速肩部强度测试的通过率为40% - 70%,等速肩部强度测试的通过率为28% - 100%,肩部耐力测试的通过率为70% - 81%,肩部性能测试的通过率为29% - 100%。这些评估是在术后4-21个月的时间框架内进行的。随后的肩部不稳定或再脱位率在恢复运动后为5%至10%。结论:客观肩部测试(包括肌肉力量和耐力以及性能测试)的通过率差异很大,恢复运动后再脱位率在5%至10%之间。然而,病例系列的优势限制了对这些试验在减少随后的肩部不稳定风险方面的有效性得出明确结论的能力。证据等级:IV级,III级研究的范围综述。
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引用次数: 0
Effects of postoperative knee bracing on knee function and stability after anterior cruciate ligament reconstruction: A systematic review and meta-analysis 前交叉韧带重建术后膝关节支架对膝关节功能和稳定性的影响:一项系统回顾和荟萃分析。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-27 DOI: 10.1002/ksa.70098
Qitai Lin, Zehao Li, Meiming Li, Xueding Wang, Qian Li, Xingguang Hou, Yongsheng Ma, Wenming Yang, Yugang Xing, Donglin Wang, Fan Yang, Wangping Duan, Xiaochun Wei
<div> <section> <h3> Purpose</h3> <p>The use of knee braces following anterior cruciate ligament reconstruction (ACLR) remains contentious. Although frequently prescribed in clinical settings, their effectiveness in enhancing postoperative recovery is uncertain. This study aimed to determine whether postoperative bracing after ACLR confers clinical benefits regarding knee function scores, pain, muscle strength, and joint stability, through a systematic review and meta-analysis.</p> </section> <section> <h3> Methods</h3> <p>A comprehensive search of PubMed, EMBASE, and the Cochrane Library was conducted through March 2025 to identify randomized controlled trials and case-control studies evaluating postoperative bracing after ACLR. Meta-analyses were performed using Review Manager (version 5.3) for the following outcomes: International Knee Documentation Committee (IKDC) objective score, Lysholm score, Tegner activity score, visual analogue scale (VAS) pain score, single-leg hop test, and side-to-side knee laxity. Bias risk evaluation was performed applying the Cochrane Risk of Bias Tool and the Newcastle-Ottawa Scale.</p> </section> <section> <h3> Results</h3> <p>A total of 785 participants across 11 studies were included, with 387 allocated to bracing and 388 to non-bracing groups. Meta-analysis revealed no significant differences between groups in IKDC objective score (odds ratio [OR] = 1.18; 95% confidence interval [CI], 0.65–2.14; <i>p</i> = 0.58), Lysholm score (mean difference [MD] = −0.30; 95% CI, −0.72 to 0.11; <i>p</i> = 0.15), Tegner score (MD = −0.22; 95% CI, −0.46 to 0.02; <i>p</i> = 0.07), VAS pain score (MD = 0.08; 95% CI, −0.15 to 0.32; <i>p</i> = 0.49), single-leg hop test (MD = 1.06; 95% CI, −0.01 to 2.14; <i>p</i> = 0.05), and anterior–posterior knee laxity (MD = −0.30; 95% CI, −0.72 to 0.11; <i>p</i> = 0.15). Subgroup analyses indicated significantly better Lysholm and Tegner scores among individuals without bracing when follow-up exceeded 2 years. No consistent differences were observed by graft type.</p> </section> <section> <h3> Conclusion</h3> <p>Postoperative bracing did not yield significant improvements in function, pain, strength, or stability following ACLR. Mid- to long-term outcomes (follow-up >2 years, up to 5 years) may favour non-bracing, indicating that routine brace use after ACLR is not warranted.</p> </section> <section> <h3> Level of Evidence</h3> <p>Level II, systematic review.</p> </section>
目的:前交叉韧带重建(ACLR)后膝关节支架的使用仍有争议。虽然在临床环境中经常开处方,但它们在促进术后恢复方面的有效性尚不确定。本研究旨在通过系统回顾和荟萃分析,确定ACLR术后支具是否能在膝关节功能评分、疼痛、肌肉力量和关节稳定性方面带来临床益处。方法:到2025年3月,对PubMed、EMBASE和Cochrane图书馆进行全面检索,以确定评估ACLR术后支架的随机对照试验和病例对照研究。使用Review Manager (version 5.3)对以下结果进行meta分析:国际膝关节文献委员会(IKDC)客观评分、Lysholm评分、Tegner活动评分、视觉模拟量表(VAS)疼痛评分、单腿跳跃测试和侧膝松弛度。应用Cochrane偏倚风险评估工具和Newcastle-Ottawa量表进行偏倚风险评估。结果:11项研究共纳入785名参与者,其中387名分配给支具组,388名分配给非支具组。荟萃分析显示组之间没有显著差异IKDC客观评分(优势比[或]= 1.18;95%可信区间(CI), 0.65 - -2.14; p = 0.58), Lysholm得分(平均差(MD) = -0.30; 95%可信区间,-0.72至0.11;p = 0.15), Tegner得分(MD = -0.22; 95%可信区间,-0.46至0.02;p = 0.07),血管疼痛评分(MD = 0.08; 95%可信区间,-0.15至0.32;p = 0.49),单腿跳测试(MD = 1.06; 95%可信区间,-0.01至2.14;p = 0.05),和前后膝盖松弛(MD = -0.30;95% CI, -0.72 ~ 0.11;p = 0.15)。亚组分析表明,随访超过2年后,未使用支具的个体Lysholm和Tegner评分显著提高。不同移植物类型间没有一致的差异。结论:ACLR术后支具在功能、疼痛、力量或稳定性方面没有显著改善。中长期结果(随访1 ~ 2年,最长5年)可能倾向于不使用支具,这表明ACLR后常规使用支具是不合理的。证据等级:二级,系统评价。
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引用次数: 0
Small language models: The big play for agentic artificial intelligence in orthopaedics 小语言模型:人工智能在骨科中的重要应用。
IF 5 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-27 DOI: 10.1002/ksa.70126
Felix C. Oettl, James A. Pruneski, Balint Zsidai, Yinan Yu, Michael T. Hirschmann, Kristian Samuelsson

While the integration of artificial intelligence in orthopedics is accelerating, the focus has largely been on powerful but resource-intensive Large Language Models (LLMs). This editorial argues for a strategic shift towards Small Language Models (SLMs) for many specialized clinical applications. SLMs offer a more efficient, cost-effective, and adaptable solution for the narrowly-scoped tasks common in orthopedics. We discuss their potential in surgical assistance, personalized patient management, and administrative automation, positing that the future of practical AI in our field lies in a diverse ecosystem of specialized SLMs. However, we also underscore that rigorous validation and the development of robust evaluation benchmarks are critical to ensure their safe and trustworthy integration into clinical practice.

虽然人工智能在骨科中的整合正在加速,但重点主要集中在功能强大但资源密集型的大型语言模型(llm)上。这篇社论主张在许多专门的临床应用中向小语言模型(SLMs)的战略转变。slm为骨科中常见的窄范围任务提供了更有效,更具成本效益和适应性的解决方案。我们讨论了它们在手术辅助、个性化患者管理和行政自动化方面的潜力,并假设我们领域实用人工智能的未来取决于专业slm的多样化生态系统。然而,我们也强调,严格的验证和开发稳健的评估基准对于确保其安全可靠地融入临床实践至关重要。
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引用次数: 0
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Knee Surgery, Sports Traumatology, Arthroscopy
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