Pub Date : 2020-03-30DOI: 10.37360/BLACPMA.20.19.2.8
A. M. Alvarado, Fernando Garcia-Trejo, Anaberta Cardador-Martínez, Fabiola Magallán-Hernández
Clinopodium mexicanum (Benth.) Govaerts (Lamiaceae) is a native plant of Mexico. This plant is used in traditional Mexican medicine for the treatment of cultural specific syndromes such as "susto", "nervios" or "espanto", conditions related to anxiety and depression. In addition, it has a high biocultural value for its medicinal and culinary use and for its exchange value in various indigenous areas of Mexico. This review aims to compile updated information about the ethnobotanical, phytochemistry and commercialization aspects of Clinopodium mexicanum, and it focuses on the potential use of this species as a raw material in the phytopharmaceutical industry for the treatment of anxiety and pain. Moreover, it would be a viable productive alternative for many rural communities, which could not only produce the raw material but who could also add value to the sale of the plant.
{"title":"Clinopodium mexicanum: potencial y dificultades para el uso de una planta medicinal mexicana","authors":"A. M. Alvarado, Fernando Garcia-Trejo, Anaberta Cardador-Martínez, Fabiola Magallán-Hernández","doi":"10.37360/BLACPMA.20.19.2.8","DOIUrl":"https://doi.org/10.37360/BLACPMA.20.19.2.8","url":null,"abstract":"Clinopodium mexicanum (Benth.) Govaerts (Lamiaceae) is a native plant of Mexico. This plant is used in traditional Mexican medicine for the treatment of cultural specific syndromes such as \"susto\", \"nervios\" or \"espanto\", conditions related to anxiety and depression. In addition, it has a high biocultural value for its medicinal and culinary use and for its exchange value in various indigenous areas of Mexico. This review aims to compile updated information about the ethnobotanical, phytochemistry and commercialization aspects of Clinopodium mexicanum, and it focuses on the potential use of this species as a raw material in the phytopharmaceutical industry for the treatment of anxiety and pain. Moreover, it would be a viable productive alternative for many rural communities, which could not only produce the raw material but who could also add value to the sale of the plant.","PeriodicalId":17966,"journal":{"name":"Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85223844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-30DOI: 10.37360/BLACPMA.20.19.2.9
Antoaneta Trendafilova, Nikolina Kutova, Gülmira Özek, Milka Todorova, Süleyman Yur, Temel Özek, Dimitar Dimitrov
The methanol extract of the Balkan endemic species Jurinea tzar-ferdinandii Davidov demonstrated weak antioxidant activity against DPPH• and ABTS+• and low inhibitory potential against acetylcholinesterase (8.3% Inh.) and tyrosinase (IC50 = 208 ± 8 μg/mL) enzymes. Phytochemical investigation of the extract led to isolation and identification of apigenin, luteolin, apigenin-7-O-glucoside, apigenin-4’-O-glucoside, apigenin-7-O-gentiobioside, luteolin-4’-O-glucoside, rutin, narcissin, chlorogenic and 1,5-dicaffeoylquinic acid. With exception of apigenin and rutin, all isolated compounds are reported for the first time in the representatives of genus Jurinea. The distribution of flavonoids was discussed from chemotaxonomic point of view.
巴尔干特有种Jurinea tzar-ferdinandii Davidov甲醇提取物对DPPH•和ABTS+•的抗氧化活性较弱，对乙酰胆碱酯酶(8.3% Inh.)和酪氨酸酶(IC50 = 208±8 μg/mL)的抑制潜力较低。通过植物化学研究，分离鉴定出芹菜素、木犀草素、芹菜素-7- o -葡萄糖苷、芹菜素-4 ' - o -葡萄糖苷、芹菜素-7- o -gentiobioside、木犀草素-4 ' - o -葡萄糖苷、芦丁、水仙素、绿原和1,5-二咖啡酰奎宁酸。除芹菜素和芦丁外，其余化合物均为首次从菊属植物中分离得到。从化学分类的角度讨论了黄酮类化合物的分布。
{"title":"Perfil fenólico y actividad antioxidante, acetilcolinesterasa e inhibidora de tirosinasa de Jurinea tzar-ferdinandii Davidov, planta endémica de los Balcanes","authors":"Antoaneta Trendafilova, Nikolina Kutova, Gülmira Özek, Milka Todorova, Süleyman Yur, Temel Özek, Dimitar Dimitrov","doi":"10.37360/BLACPMA.20.19.2.9","DOIUrl":"https://doi.org/10.37360/BLACPMA.20.19.2.9","url":null,"abstract":"The methanol extract of the Balkan endemic species Jurinea tzar-ferdinandii Davidov demonstrated weak antioxidant activity against DPPH• and ABTS+• and low inhibitory potential against acetylcholinesterase (8.3% Inh.) and tyrosinase (IC50 = 208 ± 8 μg/mL) enzymes. Phytochemical investigation of the extract led to isolation and identification of apigenin, luteolin, apigenin-7-O-glucoside, apigenin-4’-O-glucoside, apigenin-7-O-gentiobioside, luteolin-4’-O-glucoside, rutin, narcissin, chlorogenic and 1,5-dicaffeoylquinic acid. With exception of apigenin and rutin, all isolated compounds are reported for the first time in the representatives of genus Jurinea. The distribution of flavonoids was discussed from chemotaxonomic point of view.","PeriodicalId":17966,"journal":{"name":"Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80370030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-30DOI: 10.37360/BLACPMA.20.19.2.14
Julieta Orozco-Martínez, R. Lira-Saade, M. Jiménez-Estrada, Juan G. Ávila-Acevedo, R. Serrano-Parrales, T. Hernandez-Delgado
Santiago Quiotepec, one of the oldest communities of the Tehuacan-Cuicatlan Valley (Mexico), has a great tradition using medicinal plants. The aim of this study was to make an inventory of the medicinal species used by the inhabitants of Santiago Quiotepec and evaluate the antibacterial activity. An ethnobotanical study of medicinal plants was carried out, 60 informants mentioned that 66 species of plants are being used in the treatment of different diseases. Fifteen species were selected to evaluate the antibacterial activity in possible bacterial originated diseases treatment. The lowest values were presented in the hexane extract of Plumbago pulchella, with a MIC of 0.25 mg/mL over Staphylococcus aureus and S. epidermidis as well as the hexanic extract of Echinopterys eglandulosa showed a MIC of 0.25 mg/mL over Pseudomona aeruginosa.
{"title":"Plantas medicinales de Oaxaca, México: Etnobotánica y actividad antibacteriana","authors":"Julieta Orozco-Martínez, R. Lira-Saade, M. Jiménez-Estrada, Juan G. Ávila-Acevedo, R. Serrano-Parrales, T. Hernandez-Delgado","doi":"10.37360/BLACPMA.20.19.2.14","DOIUrl":"https://doi.org/10.37360/BLACPMA.20.19.2.14","url":null,"abstract":"Santiago Quiotepec, one of the oldest communities of the Tehuacan-Cuicatlan Valley (Mexico), has a great tradition using medicinal plants. The aim of this study was to make an inventory of the medicinal species used by the inhabitants of Santiago Quiotepec and evaluate the antibacterial activity. An ethnobotanical study of medicinal plants was carried out, 60 informants mentioned that 66 species of plants are being used in the treatment of different diseases. Fifteen species were selected to evaluate the antibacterial activity in possible bacterial originated diseases treatment. The lowest values were presented in the hexane extract of Plumbago pulchella, with a MIC of 0.25 mg/mL over Staphylococcus aureus and S. epidermidis as well as the hexanic extract of Echinopterys eglandulosa showed a MIC of 0.25 mg/mL over Pseudomona aeruginosa.","PeriodicalId":17966,"journal":{"name":"Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90435472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-30DOI: 10.37360/BLACPMA.20.19.2.10
Oscar M. Mosquera-Martínez, María A. Obando-Cabrera, Nathalie Ortega-Cano
The objective of this work was to evaluate the antioxidant and inhibitory activities of the ethanolic extracts of the mangosteen (Garcinia mangostana L.) grown in Montenegro, Quindio, Colombia, in three stages of maturation, including the edible (pulp) and inedible parts (pericarp and peduncle). The alcoholic samples were phytochemically characterized by Thin Layer Chromatography (TLC), High Performance Liquid Chromatography (HPLC) and by Fourier Transformation Infrared Spectroscopy (FT-IR); the antioxidant capacities were also evaluated by the diphenyl-picrylhydrazyl (DPPH•) radical method and Oxygen Radical Absorbance Capacity (ORAC), in addition to the inhibitory activity of acetylcholinesterase (AchE) and the total content of phenols and flavonoids. The tests detected phytochemical compounds such as phenols, flavonoids, alkaloids, quinones and xanthones, to which the antioxidant activity and the inhibition of AChE presented, can be attributed. In conclusion, the inedible parts of mangosteen contain higher proportions of secondary metabolites, these being the most promising sources for industrial use.
{"title":"Caracterización química y actividad antioxidante del mangostino (Garcinia mangostana L., Clusiaceae) cultivado en Colombia","authors":"Oscar M. Mosquera-Martínez, María A. Obando-Cabrera, Nathalie Ortega-Cano","doi":"10.37360/BLACPMA.20.19.2.10","DOIUrl":"https://doi.org/10.37360/BLACPMA.20.19.2.10","url":null,"abstract":"The objective of this work was to evaluate the antioxidant and inhibitory activities of the ethanolic extracts of the mangosteen (Garcinia mangostana L.) grown in Montenegro, Quindio, Colombia, in three stages of maturation, including the edible (pulp) and inedible parts (pericarp and peduncle). The alcoholic samples were phytochemically characterized by Thin Layer Chromatography (TLC), High Performance Liquid Chromatography (HPLC) and by Fourier Transformation Infrared Spectroscopy (FT-IR); the antioxidant capacities were also evaluated by the diphenyl-picrylhydrazyl (DPPH•) radical method and Oxygen Radical Absorbance Capacity (ORAC), in addition to the inhibitory activity of acetylcholinesterase (AchE) and the total content of phenols and flavonoids. The tests detected phytochemical compounds such as phenols, flavonoids, alkaloids, quinones and xanthones, to which the antioxidant activity and the inhibition of AChE presented, can be attributed. In conclusion, the inedible parts of mangosteen contain higher proportions of secondary metabolites, these being the most promising sources for industrial use.","PeriodicalId":17966,"journal":{"name":"Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78370913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-30DOI: 10.37360/BLACPMA.20.19.2.11
Ricardo Lobo, Ana Cristina Bastos Nigro Monteiro Lobo, Antônio Fernando Morais Oliveira, L. Andrade
Gypsies have been in Brazil since the 16th century and today they are more than 800,000 in the country. This article describes the veterinary use of plants by Calon gypsies living in Pernambuco, Northeastern Brazil. The research was carried out with 23 people (> 40 years old), using semi-structured forms and the snowball technique. The cited species were collected during guided tours, identified and deposited at the IPA and UFP herbaria. Ten plants were indicated for veterinary use: Agave sisalana (Asparagaceae), Aspidosperma pyrifolium (Apocynaceae), Apodanthera congestiflora (Cucurbitaceae), Heliotropium indicum (Boraginaceae), Lippia alba (Verbenaceae), Momordica charantia (Cucurbitaceae), Nicotiana tabacum (Solanaceae), Passiflora cincinnata (Passifloraceae), Phaseolus lunatus (Fabaceae), and Solanum paniculatum (Solanaceae). The participants cited various methods of preparation and therapeutic indications for ectoparasitic infections, digestive disorders, and eye and respiratory infections in farm animals. Apodanthera congestiflora and H. indicum stood out for prophylaxis and treatment of Newcastle disease in fowl.
{"title":"Plantas etnomedicinales para uso veterinario en comunidades gitanas del noreste de Brasil","authors":"Ricardo Lobo, Ana Cristina Bastos Nigro Monteiro Lobo, Antônio Fernando Morais Oliveira, L. Andrade","doi":"10.37360/BLACPMA.20.19.2.11","DOIUrl":"https://doi.org/10.37360/BLACPMA.20.19.2.11","url":null,"abstract":"Gypsies have been in Brazil since the 16th century and today they are more than 800,000 in the country. This article describes the veterinary use of plants by Calon gypsies living in Pernambuco, Northeastern Brazil. The research was carried out with 23 people (> 40 years old), using semi-structured forms and the snowball technique. The cited species were collected during guided tours, identified and deposited at the IPA and UFP herbaria. Ten plants were indicated for veterinary use: Agave sisalana (Asparagaceae), Aspidosperma pyrifolium (Apocynaceae), Apodanthera congestiflora (Cucurbitaceae), Heliotropium indicum (Boraginaceae), Lippia alba (Verbenaceae), Momordica charantia (Cucurbitaceae), Nicotiana tabacum (Solanaceae), Passiflora cincinnata (Passifloraceae), Phaseolus lunatus (Fabaceae), and Solanum paniculatum (Solanaceae). The participants cited various methods of preparation and therapeutic indications for ectoparasitic infections, digestive disorders, and eye and respiratory infections in farm animals. Apodanthera congestiflora and H. indicum stood out for prophylaxis and treatment of Newcastle disease in fowl.","PeriodicalId":17966,"journal":{"name":"Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79603023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chloroform extract (CE) and fractions obtained from Aldama arenaria roots were evaluated for their in vitro antiproliferative activity against 10 human tumor cell lines [leukemia (K-562), breast (MCF-7), ovary expressing a multidrug-resistant phenotype (NCI/ADR-RES), melanoma (UACC-62), lung (NCI-H460), prostate (PC-3), colon (HT29), ovary (OVCAR-3), glioma (U251), and kidney (786-0)]. CE presented weak to moderate antiproliferative activity (mean log GI50 1.07), whereas fractions 3 and 4, enriched with pimarane-type diterpenes [ent-pimara-8(14),15-dien-19-oic acid and ent-8(14),15-pimaradien-3β-ol], presented moderate to potent activity for most cell lines, with mean log GI50 of 0.62 and 0.59, respectively. The results showed promising in vitro antiproliferative action of the samples obtained from A. arenaria, with the best results for NCI/ADR-RES, HT29, and OVCAR-3, and TGI values ranging from 5.95 to 28.71 μg.ml-1, demonstrating that compounds of this class may be potential prototypes for the discovery of new therapeutic agents.
{"title":"Estudio etnobotánico de Plectranthus neochilus Schltr (Meprobamato) en Cuba","authors":"Annarli Olivia Rodríguez-Ferreiro, Dalgis Léon-Duharte, Gustavo Polanco-Durán, Frenkel Guisado-Bourzac, Ania Ochoa-Pacheco, Julio César Escalona-Arranz","doi":"10.37360/BLACPMA.20.19.2.15","DOIUrl":"https://doi.org/10.37360/BLACPMA.20.19.2.15","url":null,"abstract":"Chloroform extract (CE) and fractions obtained from Aldama arenaria roots were evaluated for their in vitro antiproliferative activity against 10 human tumor cell lines [leukemia (K-562), breast (MCF-7), ovary expressing a multidrug-resistant phenotype (NCI/ADR-RES), melanoma (UACC-62), lung (NCI-H460), prostate (PC-3), colon (HT29), ovary (OVCAR-3), glioma (U251), and kidney (786-0)]. CE presented weak to moderate antiproliferative activity (mean log GI50 1.07), whereas fractions 3 and 4, enriched with pimarane-type diterpenes [ent-pimara-8(14),15-dien-19-oic acid and ent-8(14),15-pimaradien-3β-ol], presented moderate to potent activity for most cell lines, with mean log GI50 of 0.62 and 0.59, respectively. The results showed promising in vitro antiproliferative action of the samples obtained from A. arenaria, with the best results for NCI/ADR-RES, HT29, and OVCAR-3, and TGI values ranging from 5.95 to 28.71 μg.ml-1, demonstrating that compounds of this class may be potential prototypes for the discovery of new therapeutic agents.","PeriodicalId":17966,"journal":{"name":"Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90554767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-30DOI: 10.37360/BLACPMA.20.19.2.13
Maritza Obando-Camino, Miguel Silva, R. Zemelman
The objective of this study was to confirm the existing scientific evidence of the therapeutical properties of Chilean plants to be used as medicine by Machis of the Araucania and Los Rios Chilean regions. The study was performed in two periods at four mapuche communities of these regions, between July 2015 to March 2016 and the second stage from August to December 2017. Semi-structured interviews were conducted with the Machis, where the information delivered on the medicinal applications it was agreed among all participants. The identified plants were compared in their properties with the experimental evidence reported, verifying the indicated properties. The results offer an additional criteria for selecting plants to be used in the corresponding diseases of Chilean population. The results of this study support for some species of plants used their medicinal properties on oncological diseases. These facts require the necessary clinical support in order to prove as therapeutic treatment.
{"title":"Evidencia científica de las propiedades medicinales de plantas para su uso en la medicina intercultural de Chile","authors":"Maritza Obando-Camino, Miguel Silva, R. Zemelman","doi":"10.37360/BLACPMA.20.19.2.13","DOIUrl":"https://doi.org/10.37360/BLACPMA.20.19.2.13","url":null,"abstract":"The objective of this study was to confirm the existing scientific evidence of the therapeutical properties of Chilean plants to be used as medicine by Machis of the Araucania and Los Rios Chilean regions. The study was performed in two periods at four mapuche communities of these regions, between July 2015 to March 2016 and the second stage from August to December 2017. Semi-structured interviews were conducted with the Machis, where the information delivered on the medicinal applications it was agreed among all participants. The identified plants were compared in their properties with the experimental evidence reported, verifying the indicated properties. The results offer an additional criteria for selecting plants to be used in the corresponding diseases of Chilean population. The results of this study support for some species of plants used their medicinal properties on oncological diseases. These facts require the necessary clinical support in order to prove as therapeutic treatment.","PeriodicalId":17966,"journal":{"name":"Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72984647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.37360/BLACPMA.20.19.2.12
Rashid Mahmood, Farnaz Malik, Shazia Shamas, Tanveer Ahmed, Mehran Kausar, Samina Rubnawaz, Muhammad Ashfaq, S. Hussain, Brian D. Green, Bushra Mirza
The present study aimed to screen the Rhazya stricta Decne root for its antihyperglycemic and antioxidants potential through in-vitro assays along with phytochemical and elemental analyses. The crude extract was prepared through maceration and fractionated using solvent-solvent extraction technique. The spectroscopic studies indicated the presence of various phytochemical classes in the extract and its fractions. The antioxidant assays showed notable results along with a good concentration of phenolic and flavonoid contents. Enzyme inhibition assays demonstrated glucose-lowering effects by inhibiting the enzyme activity which could reduce post-prandial blood glucose level. The Dipeptidyl peptidase-IV (DPP-IV) inhibition assay results showed the novel DPP-IV inhibition activity of the plant extract and all fractions showed noteworthy enzyme inhibition and antihyperglycemic activity. Conclusively, the Rhazya stricta root extract displayed its antioxidant and antihyperglycemic potential due to the presence of various classes of phytochemicals and micro-nutrients.
本研究旨在通过体外实验、植物化学分析和元素分析等方法，筛选赤叶根的抗高血糖和抗氧化活性。采用溶剂-溶剂萃取法，经浸渍分馏制备粗提物。光谱学研究表明，提取物及其组分中存在多种植物化学成分。抗氧化实验结果显著，酚类和类黄酮含量较高。酶抑制实验表明，通过抑制酶活性降低餐后血糖水平，具有降低血糖的作用。二肽基肽酶- iv (DPP-IV)抑制实验结果表明，该植物提取物具有新型的DPP-IV抑制活性，各组分均表现出明显的酶抑制和降糖活性。综上所述，由于存在各种类型的植物化学物质和微量营养素，拉孜亚根提取物显示出其抗氧化和降高血糖的潜力。
{"title":"Evaluación farmacológica del extracto de Raíz de rhazya stricta","authors":"Rashid Mahmood, Farnaz Malik, Shazia Shamas, Tanveer Ahmed, Mehran Kausar, Samina Rubnawaz, Muhammad Ashfaq, S. Hussain, Brian D. Green, Bushra Mirza","doi":"10.37360/BLACPMA.20.19.2.12","DOIUrl":"https://doi.org/10.37360/BLACPMA.20.19.2.12","url":null,"abstract":"The present study aimed to screen the Rhazya stricta Decne root for its antihyperglycemic and antioxidants potential through in-vitro assays along with phytochemical and elemental analyses. The crude extract was prepared through maceration and fractionated using solvent-solvent extraction technique. The spectroscopic studies indicated the presence of various phytochemical classes in the extract and its fractions. The antioxidant assays showed notable results along with a good concentration of phenolic and flavonoid contents. Enzyme inhibition assays demonstrated glucose-lowering effects by inhibiting the enzyme activity which could reduce post-prandial blood glucose level. The Dipeptidyl peptidase-IV (DPP-IV) inhibition assay results showed the novel DPP-IV inhibition activity of the plant extract and all fractions showed noteworthy enzyme inhibition and antihyperglycemic activity. Conclusively, the Rhazya stricta root extract displayed its antioxidant and antihyperglycemic potential due to the presence of various classes of phytochemicals and micro-nutrients.","PeriodicalId":17966,"journal":{"name":"Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76457757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-30DOI: 10.37360/BLACPMA.19.18.3.21
Julio Benites, Holbert D. Asunción-Alvarez, Roberto O. Ybañez-Julca, Mayar L. Ganoza-Yupanqui, Juan J. Jacinto-Fernandez, Junior B. Reyes-De la Vega, Hair J. Zavaleta-Cruz, Adela N. Pinedo-Alcántara, Cristian M. Lavado-Fonseca, Carlos A. Medina-Mejia, M. Catalán, Bernardo Morales, R. D. D. G. D. Albuquerque, Leandro Rocha, José L. Martínez
The chemical composition of Mangifera indica L. cv. "Kent" leaves was determined by HPLC-ESI-QTOF-MS/MS. Polyphenolic compounds characterized as benzophenone derivatives were the main components found in extracts (1, maclurin 3-C-(2-O-galloyl)-D-glucoside isomer; 2, maclurin 3-C---D-glucoside; 3, iriflophenone 3-C---D-glucoside; 5, maclurin 3-C-(2,3-di-O-galloyl)---D-glucoside; 6, iriflophenone 3-C-(2-O-galloyl)---D-glucoside; 7, methyl-iriflophenone 3-C-(2,6-di-O-galloyl)---D-glucoside) and xanthones (4, mangiferin and 8, 6-O-galloyl-mangiferin). The estrogenic and antioxidant effects of aqueous extracts from Mangifera indica L. cv. "Kent" leaves on ovariectomized rats were determined by uterotrophic assay and malondialdehyde (MDA) levels in erythrocytes, bone, liver, and stomach. We conclude that the polyphenolic compounds from extracts act as exogenous antioxidant agents against oxidative damage in ovariectomized rats.
芒果的化学成分。采用HPLC-ESI-QTOF-MS/MS对“Kent”叶片进行测定。以二苯甲酮衍生物为主要成分的多酚类化合物(1、大柳苷3-C-(2- o -没食子酰)- d -葡萄糖苷异构体;2、maclurin 3-C-——d -葡萄糖苷;3、环氟苯酮3- c -——d -葡萄糖苷;5、maclurin 3-C-(2,3-二- o -没食子酰)-- d -葡萄糖苷;6、环氟苯酮3-C-(2- o -没食子酰)-- d -葡萄糖苷;7、甲基环氟苯酮3-C-(2,6-二- o -没食子酰基)-- d -葡萄糖苷)和山酮(4,6 - o -没食子酰基芒果苷和8,6 - o -没食子酰基芒果苷)。芒果水提物的雌激素和抗氧化作用。采用子宫营养测定法和红细胞、骨、肝、胃中丙二醛(MDA)水平测定去卵巢大鼠的“肯特”叶。我们得出结论，从提取物中提取的多酚类化合物作为外源性抗氧化剂对卵巢切除大鼠的氧化损伤起作用。
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Pub Date : 2010-01-01DOI: 10.1080/12460125.1995.10511649
J. L. Martínez
EDITOR JEFE | EDITOR IN CHIEF Jose L. Martinez (Universidad de Santiago de Chile – Santiago, Chile) EDITORES CIENTIFICOS | SCIENTIFIC EDITORS Alejandro Urzua (Universidad de Santiago de Chile – Santiago, Chile) EDITORES EJECUTIVOS | MANAGING EDITORS Julio Alarcon (Universidad del Bio Bio - Chillan, Chile) Arnaldo Bandoni (Universidad de Buenos Aires – Buenos Aires, Argentina)...
编辑/ IN首席主编何塞·马丁内斯(智利圣地亚哥大学—圣地亚哥,智利)编辑科学家亚历山大- SCIENTIFIC EDITORS Urzua(智利圣地亚哥大学—7,智利圣地亚哥)执行编辑/ MANAGING EDITORS全国(Bio Bio -他们诉苦,智利大学)Arnaldo Bandoni(布宜诺斯艾利斯大学—阿根廷,布宜诺斯艾利斯)...
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