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Ultra High Efficiency Protein Separations with Submicrometer Silica Using Slip Flow. 亚微米二氧化硅滑流超高效蛋白质分离。
IF 0.9 4区 化学 Q4 Chemistry Pub Date : 2012-10-01
Benjamin J Rogers, Bingchuan Wei, Mary J Wirth
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引用次数: 0
Analytical Method Transfer 分析方法转移
IF 0.9 4区 化学 Q4 Chemistry Pub Date : 2012-04-24 DOI: 10.1201/B12039-9
M. Swartz, I. Krull
The objective of a formal method transfer is to ensure that the receiving laboratory is well trained, qualified to run the method in question, and gets the same results witing experimental error as the iniating laboratory. The development and validation of robust methods and strict adherence to well documented standart operating procedures is the best way to ensure the ultimate sucess of the methode. This installment of ''Validation Viewponit'' examines the analytical method transfer process, including protocol, documentation, and some possible chromatographic pitfalls to avoid.
正式方法转移的目的是确保接收实验室受过良好的培训,有资格运行所讨论的方法,并且在实验误差范围内得到与初始实验室相同的结果。开发和验证可靠的方法,并严格遵守记录良好的标准操作程序,是确保该方法最终成功的最佳途径。“验证观点”的这一部分检查了分析方法转移过程,包括协议、文档和一些可能避免的色谱陷阱。
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引用次数: 7
Chemometrical Experimental Design‐Based Optimization Studies in Capillary Electrophoresis Applications 基于化学计量学实验设计的毛细管电泳应用优化研究
IF 0.9 4区 化学 Q4 Chemistry Pub Date : 2009-11-03 DOI: 10.1002/9780470530191.CH3
R. Montes, T. Riveros, Froseen Dahdouh, G. Hanrahan, F. Gomez
A synopsis of the authors' work detailing the use of chemometric response surface methodology (RSM) in two capillary electrophoresis (CE) studies is described. They demonstrate the usefulness of employing RSM to specific CE applications, thereby proving the utility of chemometrics design in experimental optimization.
简要介绍了作者的工作,详细介绍了化学计量响应面法(RSM)在两个毛细管电泳(CE)研究中的应用。他们证明了将RSM应用于特定CE应用的实用性,从而证明了化学计量学设计在实验优化中的实用性。
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引用次数: 2
M.S. Tswett and the invention of chromatography ms . Tswett和色谱法的发明
IF 0.9 4区 化学 Q4 Chemistry Pub Date : 2008-06-01 DOI: 10.1142/9781860949449_0005
L. Ettre
On the occasion of the centenary of the invention of chromatography, this month's Milestones in Chromatography column chronicles the life and activities of its inventor, his struggle for acceptance, and, finally, the triumph of his technique.
值此色谱法发明一百周年之际,本月的色谱法里程碑专栏记录了色谱法发明者的生平和活动,他为被接受而进行的斗争,以及他的技术最终取得的胜利。
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引用次数: 21
Jim waters : The development of GPC and the first commercial HPLC instruments 吉姆·沃特斯:GPC的发展和第一个商用HPLC仪器
IF 0.9 4区 化学 Q4 Chemistry Pub Date : 2008-06-01 DOI: 10.1142/9781860949449_0029
L. Ettre
This month's installment of Milestones in Chromatography deals with the involvement of James L. Waters in two major chromatography developments: the introduction of instrumentation for gel-permeation chromatography and the establishment of Waters Associates as the Liquid Chromatography People.
本月的《色谱学里程碑》将介绍James L. Waters在色谱学两大发展中的作用:凝胶渗透色谱仪的引入以及作为液相色谱人的Waters Associates的成立。
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引用次数: 5
The development of the amino acid analyzer 氨基酸分析仪的研制
IF 0.9 4区 化学 Q4 Chemistry Pub Date : 2006-01-01 DOI: 10.1142/9781860949449_0019
L. Ettre
This installment of “Millestones in Chromatography”discusses the events leading to the development of the amino acid analyzer near the end of the 1950s at The Rockefeller Institute of Medical Research by Moore, Stein, and Spackman.
“色谱中的里程碑”的这一部分讨论了在20世纪50年代末,由Moore、Stein和Spackman在洛克菲勒医学研究所开发氨基酸分析仪的事件。
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引用次数: 4
Implementing New Technology in a Regulated Environment 在受规管的环境下实施新科技
IF 0.9 4区 化学 Q4 Chemistry Pub Date : 2006-01-01 DOI: 10.1201/B12039-10
M. Swartz, I. Krull
Over the course of a drug product's life (as much as 15-20 years or more) many significant advances in technology will occur. Implementing new analytical techniques (for example, capillary electrophoresis), or advances in existing technology (for example, sub-2-μm liquid chromatography [LC]) can significantly impact business practices (return on investment) and product quality. However, in a regulated laboratory, implementing new technology can present many challenges.
在药品的生命周期(长达15-20年或更长时间)中,将会发生许多重大的技术进步。实施新的分析技术(例如,毛细管电泳)或现有技术的进步(例如,亚2 μm液相色谱[LC])可以显著影响业务实践(投资回报)和产品质量。然而,在一个受监管的实验室中,实施新技术可能会带来许多挑战。
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引用次数: 0
Bridging the performance gap from analytical to preparative chromatography : Efficient target isolation from a complex mixture 弥合从分析色谱到制备色谱的性能差距:从复杂混合物中有效地分离目标
IF 0.9 4区 化学 Q4 Chemistry Pub Date : 2005-01-01 DOI: 10.1021/cen-v083n023.obc
Fang Xia, Jie Y. Cavanaugh, D. Diehl
SunFire C 18 analytical and OBD preparative columns are designed to provide maximum loadability in simple mobile phase conditions, accurate scalability, and high peak capacity.
SunFire C 18分析和OBD制备柱设计用于在简单的流动相条件下提供最大的负载性,准确的可扩展性和高峰值容量。
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引用次数: 0
The Janák-type gas chromatographs of the 1950s 上世纪50年代的Janák-type气相色谱仪
IF 0.9 4区 化学 Q4 Chemistry Pub Date : 2002-01-01 DOI: 10.1142/9781860949449_0021
L. Ettre
A special type of instrument that permitted the volume of collected fractions to be read directly was very popular in the early days of gas chromatography. This Milestones in Chromatography column deals with the development and applications of this long-forgotten unit.
在早期的气相色谱法中,有一种特殊类型的仪器可以直接读取所收集的馏分的体积。这个里程碑色谱柱处理的发展和应用这个长期被遗忘的单位。
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引用次数: 0
The beginnings of headspace analysis 头顶空间分析的开始
IF 0.9 4区 化学 Q4 Chemistry Pub Date : 2002-01-01 DOI: 10.1142/9781860949449_0026
L. Ettre
Today, headspace analysis is one of the most frequently used sampling methods in gas chromatography. This month's Milestones in Chromatography column discusses the technique's beginning and early uses, particularly in food science and in the determination of blood alcohol, and outlines the development of the first automated instrument integrating headspace sampling with a gas chromatograph.
如今,顶空分析是气相色谱中最常用的采样方法之一。本月色谱的里程碑专栏讨论了该技术的开始和早期应用,特别是在食品科学和血液酒精测定方面,并概述了首台将顶空采样和气相色谱仪集成的自动化仪器的开发。
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引用次数: 4
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Lc Gc North America
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