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Development of rice farming: a cause of the emergence of multiple insecticide resistance in populations of Anopheles gambiae s.l and its impact on human health in Malanville, Bénin 水稻种植的发展:冈比亚按蚊种群出现多种杀虫剂抗性的一个原因及其对bsamin Malanville人类健康的影响
4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-10-11 DOI: 10.4314/mmj.v35i3.6
YADOULETON Anges, BADOU Yvette, SANOUSSI Falilath, HOUNKANRIN Gildas, TCHIBOZO Carine, ADEWUMI Praise, BABA-MOUSSA Lamine
AimThe rise in rice production in the district of Malanville, Northen Benin, is a present concern, as it has resulted in the widespread usage of pesticides for crop protection. This could impact human health but also life cycle of Anopheles gambiae, the main vector of malaria.Methods Therefore, insecticide susceptibility bioassays were carried out on populations of An. gambiae s.l aged to 3-5 days old (two from areas where insecticide is highly used and other two areas of low insecticide use) and subjected to insecticide-impregnated papers (Permethrin 0.75%; deltamethrin 0.05%; DDT 4% and bendiocarb 0.1%) following WHO protocol. Polymerase Chain Reactions (PCRs) were used for the detection of Acethlylcholinestrase (Ace-1) and the knock down resistance (kdr) L1014F mutations in An. gambiae populations. Finally, indirect bioassays were conducted for the investigating on the factors affecting the life cycle of An. gambiae due to the use of pesticides.Results An. gambiae from the four sites were resistant to DDT (6 to 8% and 10 to 14% respectively from areas of high and low dose), pyrethroids (22 to 26% and 30 to 36% for permethrin, from areas of high and low dose respectively and 66 to 70% and 72 to 80% for deltamethrin, from high and low dose) but susceptible to carbamate. The kdr L1014F mutation was detected in An. gambiae populations (0.88 to 0.90 and 0.84 to 0.88 from high and low dose, respectively). The ace-1 was detected at low frequencies (<0.002). Bioassays on the impacts of the use of pesticides in the life cycle of An. gambiae showed that soil substrates with pesticides residues have a negative impact on the life cycle eggs of An. gambiae. ConclusionThese findings confirmed the negative impacts of pesticides use in rice farming and its impacts on the life cycle of An. gambiae.
目的贝宁北部Malanville地区水稻产量的增加是目前的一个问题,因为它导致广泛使用农药进行作物保护。这可能会影响人类健康,但也会影响疟疾的主要媒介冈比亚按蚊的生命周期。方法采用药敏生物测定法对大蠊种群进行杀虫剂敏感性测定。出生3-5天的冈比亚蚊(2只来自杀虫剂使用量大的地区,另外2只来自杀虫剂使用量小的地区),并使用杀虫剂浸渍纸(氯菊酯0.75%;溴氰菊酯0.05%;滴滴涕4%和恶虫威0.1%)。采用聚合酶链反应(pcr)技术检测安氏杆菌中乙酰胆碱酯酶(Ace-1)和低敲抗性(kdr) L1014F突变。冈比亚按蚊的种群。最后,采用间接生物测定法探讨了影响黄芪生命周期的因素。冈比亚因使用杀虫剂而死亡。一个结果。4个地点的冈比亚蚊对滴滴涕(高、低剂量区分别为6 ~ 8%和10 ~ 14%)和拟除虫菊酯(高、低剂量区分别为22 ~ 26%和30 ~ 36%,高、低剂量区分别为66 ~ 70%和72 ~ 80%)耐药,但对氨基甲酸酯敏感。在An中检测到kdr L1014F突变。冈比亚种群(高剂量和低剂量分别为0.88至0.90和0.84至0.88)。在低频率(<0.002)检测到ace-1。农药使用对柽柳生命周期影响的生物测定。结果表明,含农药残留的土壤基质对甘贝卵的生命周期有负面影响。冈比亚按蚊。结论水稻种植中农药的使用对水稻种群的影响及其对水稻种群生命周期的影响。冈比亚按蚊。
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引用次数: 0
The Socioeconomic consequences of femoral shaft fracture for patients in Malawi 马拉维患者股骨干骨折的社会经济后果
4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-10-11 DOI: 10.4314/mmj.v35i3.2
Kush S. Mody, Hao-Hua Wu, Linda C. Chokotho, Nyengo C. Mkandawire, Sven Young, Brian C. Lau, David Shearer, Kiran J. Agarwal- Harding
BackgroundFemoral shaft fractures are common in Malawi, with an annual incidence of 44 per 100,000 people. Inadequate treatment and delayed presentation often result in functional, biopsychosocial, and financial challenges for patients. The purpose of this study was to examine the socioeconomic consequences of femoral shaft fractures for patients in Malawi. Methods This study of 42 patients was part of a larger study that prospectively examined quality of life. Questionnaires were distributed to patients at 1-year follow-up following femoral shaft fracture treatment. Patients reported pre- and post-injury standard of living and financial well-being. Results Patients reported relatively high transportation costs to and from the hospital. One year after injury, 17 patients (40%) had not returned to work. Of the 25 (60%) who had returned, 5 (20%) changed jobs due to their injury, all reported decreased productivity. Household income decreased for 29% of patients. 20 (49%) of 41 patients reported food insecurity in the week prior to questionnaire completion. Many patients reported changing their residence, borrowing money, selling personal property, and unenrolling children from school due to financial hardship caused by their injury. Conclusion While the Malawian public healthcare system is free at the point of care, it lacks the financial risk protection that is essential to universal health coverage (UHC). In this study, we found that the indirect costs of care due to femoral shaft fractures had substantial socioeconomic consequences on the majority of patients and their families. Increased investment of financial and human capital should be made into capacity building and preventative measures to decrease the burden of injury, increase access to care, improve care delivery, and provide financial risk protection for patients with traumatic injuries in Malawi.
股骨干骨折在马拉维很常见,年发病率为每10万人44例。不适当的治疗和延迟的表现往往导致患者的功能,生物心理社会和经济方面的挑战。本研究的目的是研究马拉维股骨骨干骨折患者的社会经济后果。方法本研究纳入了42例患者,是一项更大的前瞻性生活质量研究的一部分。对股骨骨干骨折治疗后随访1年的患者发放问卷。患者报告了受伤前后的生活水平和经济状况。结果患者往返医院的交通费用较高。伤后1年,17例患者(40%)未重返工作岗位。在返工的25人(60%)中,5人(20%)因受伤而换了工作,他们都表示生产率下降了。29%的患者家庭收入下降。41名患者中有20名(49%)在完成问卷前一周报告食物不安全。许多患者报告说,由于受伤造成的经济困难,他们改变了居住地,借钱,出售个人财产,并让孩子辍学。结论:虽然马拉维的公共卫生系统在医疗点是免费的,但它缺乏对全民健康覆盖至关重要的财务风险保护。在这项研究中,我们发现股骨干骨折的间接护理成本对大多数患者及其家庭产生了重大的社会经济影响。应在能力建设和预防措施方面增加财政和人力资本投资,以减少伤害负担,增加获得护理的机会,改善护理服务,并为马拉维的创伤性伤害患者提供财务风险保护。
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引用次数: 0
Three-year follow-up outcomes of adult patients with Guillain-Barré Syndrome after rehabilitation 成年格林-巴罗综合征患者康复后三年随访结果
4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-10-11 DOI: 10.4314/mmj.v35i3.4
Fatma Ballı Uz, Cuma Uz, Ozgur Zeliha Karaahmet
Background Guillain-Barré syndrome (GBS), the most common cause of acute paralytic neuropathy, covers a number of recognizably different variants. We aimed to evaluate the clinical characteristics of the patients with GBS and the outcome results of the patients after rehabilitation.Methods We enrolled 24 adult patients with GBS and evaluated their demographic characteristics, signs, complications, functional levels, and residual symptoms at admission, discharge, and during the 1st and 3rd-year follow-up visits. Functional Independence Scale (FIM), Functional Ambulation Scale (FAS), Hughes functional grading scale, Six-Minute Walking Test (6MWT), and Fatigue Severity Scale (FSS) were used for patient evaluation.Results In this study, patients with a mean age of 47.29 ± 16.2 years (40% female) were hospitalized for an average of 28.91 ± 25.6 days. The predominant symptoms experienced by these patients were fatigue (100%), neuropathic pain (70.8%), joint pain (54.2%), and autonomic dysfunction (50%). Significant changes were observed in FIM, Hughes functional grading scale, FAS, 6MWT, and MRC score at admission, discharge, and 1st/3rd-year follow-ups (p=0.000, p=0.000, p=0.000, p=0.001, p=0.000, respectively). Fatigue and Hughes score increased significantly with age (p=0.019, r=0.475; p=0.041, r=0.419, respectively). Negative correlations were found between age and FAS, 6MWT, and MRC score at 1st-year follow-up (p=0.025, r=-0.456; p=0.027, r=-0.450; p=0.008, r=-0.528). FSS was above 4 before admission and in 53.1% at 3rd-year follow-up, correlating negatively with 6MWT and MRC sum score. GBS clinical types showed no significant differences. ConclusionRehabilitation improves functional improvement in GBS patients, with long-term benefits observed. However, residual symptoms such as fatigue and neuropathic pain may persist despite functional improvement. These findings highlight the importance of incorporating rehabilitation into the management of GBS and addressing residual symptoms to improve patient outcomes.
吉兰-巴罗综合征(GBS)是急性麻痹性神经病变最常见的病因,涵盖了许多可识别的不同变体。我们的目的是评估GBS患者的临床特征和患者康复后的结果。方法:我们招募了24例成年GBS患者,并在入院、出院、1年和3年随访期间评估他们的人口统计学特征、体征、并发症、功能水平和残留症状。采用功能独立量表(FIM)、功能步行量表(FAS)、Hughes功能分级量表、6分钟步行测试(6MWT)和疲劳严重程度量表(FSS)对患者进行评估。结果本组患者平均年龄47.29±16.2岁,其中女性占40%,平均住院时间28.91±25.6天。这些患者的主要症状是疲劳(100%)、神经性疼痛(70.8%)、关节疼痛(54.2%)和自主神经功能障碍(50%)。入院、出院和1 /3年随访时,FIM、Hughes功能分级量表、FAS、6MWT和MRC评分均发生显著变化(p=0.000, p=0.000, p=0.000, p=0.001, p=0.000)。随着年龄的增长,疲劳和休斯评分显著增加(p=0.019, r=0.475;P =0.041, r=0.419)。1年随访时,年龄与FAS、6MWT、MRC评分呈负相关(p=0.025, r=-0.456;p = 0.027, r = -0.450;p = 0.008, r = -0.528)。入院前FSS≥4分,随访3年时FSS≥53.1%,与6MWT、MRC总分呈负相关。GBS临床分型差异无统计学意义。结论康复治疗可改善GBS患者的功能,并可观察到远期疗效。然而,尽管功能改善,残余症状如疲劳和神经性疼痛可能持续存在。这些发现强调了将康复纳入GBS管理和解决残留症状以改善患者预后的重要性。
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引用次数: 0
Is it possible to predict Surgical Site Infection? 是否有可能预测手术部位感染?
4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-10-11 DOI: 10.4314/mmj.v35i3.9
Sezgi Gullu Erciyestepe, Ahmet Birtan Boran, Merve Sezer Yildirim, Mert Erciyestepe
IntroductionSurgical site infection (SSI) is a widely seen postoperative complication that causes a decrease in life quality and an economic burden. In this study, we aim to find the predictive values of preoperative and postoperative neutrophile lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) values for SSI.MethodsIn this retrospective study, 698 patients who had total abdominal hysterectomy operations with benign indications and confirmed histopathological results were accessed. In this study, the correlation of preoperative NLR, preoperative PLR, postoperative NLR, and postoperative PLR, with the occurrence of postoperative surgical site infection complications were examined. Results The overall SSI rate was 9.46% (n = 66) with 30 days follow-up postoperatively. Preoperative NLR and PLR values of the patients who had SSIs were significantly lower than the control group (p < 0.05). Postoperative NLR and PLR values of the patients who had SSIs were significantly higher than control group (p < 0.05). In the patients who had postoperative SSIs, the increase of the values of postoperative NLR and PLR were significantly higher than the control group (p < 0.05).ConclusionsIn our study, hematological markers of NLR and PLR were found to be independent and significant predictive markers for SSI.
手术部位感染(SSI)是一种常见的术后并发症,会导致生活质量下降和经济负担。在本研究中,我们旨在发现术前和术后中性粒细胞淋巴细胞比率(NLR)和血小板淋巴细胞比率(PLR)值对SSI的预测价值。方法回顾性分析698例经腹式全子宫切除术的良性指征及病理组织学检查结果。本研究探讨术前NLR、术前PLR、术后NLR、术后PLR与术后手术部位感染并发症发生的相关性。结果术后随访30 d, SSI总发生率为9.46% (n = 66)。ssi患者术前NLR、PLR值均显著低于对照组(p <0.05)。ssi患者术后NLR和PLR值显著高于对照组(p <0.05)。术后发生ssi的患者,术后NLR和PLR值的升高均显著高于对照组(p <0.05)。结论在我们的研究中,NLR和PLR的血液学指标被发现是SSI的独立且重要的预测指标。
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引用次数: 0
The Self-efficacy of Malawian Nursing Educators towards the use of Case Study Teaching Method 马拉维护理教育工作者对案例研究教学法的自我效能感
4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-08-02 DOI: 10.4314/mmj.v35i2.3
Burnett Chila Chiona, Masauko Msiska
Introduction The case study teaching method is important in imparting critical thinking and clinical reasoning skills in nursing students. The self-efficacy of the nurse educators towards the use of the case study teaching method is a critical aspect of determining the quality of teaching using this method. This study, therefore, aimed at assessing the self-efficacy of the nurse educators towards the use of the case study teaching method in Malawi. MethodA cross-sectional study utilizing a quantitative research design was conducted at eight nursing colleges that are under the Christian Health Association of Malawi. Only nursing colleges offering college diplomas in nursing and midwifery technician were involved. A total of 145 nurse educators completed the Self-Efficacy towards Teaching Inventory. The computer software of Statistical Package for Social Sciences version 23.0 was used to analyze the data.Results The results show that the nurse educators are confident in using the case study teaching method (mean=78.4, SD=11.166). The study results also show that there are differences in mean scores between the nurse educators who attended an education workshop and those who did not (t=5.2334; P<0.001). Conclusion The study indicates that Malawian nurse educators have moderate levels of self-efficacy in using the case study teaching method. This study, therefore, has shown a need for nurse educators to participate in strategies that can increase their level of self-efficacy in using case studies.
案例教学法对护理学生批判性思维和临床推理能力的培养具有重要意义。护理教育工作者对使用案例研究教学法的自我效能感是决定使用该方法的教学质量的关键方面。因此,本研究旨在评估马拉维护士教育工作者对使用案例研究教学法的自我效能感。方法在马拉维基督教健康协会下属的八所护理学院进行了一项采用定量研究设计的横断面研究。仅涉及提供护理和助产技术大学文凭的护理学院。共有145名护士教育工作者完成了教学自我效能感量表。采用统计软件包社会科学23.0版计算机软件进行数据分析。结果护理教育工作者对案例教学法的应用有信心(均值78.4,SD=11.166)。研究结果还显示,参加教育研讨会的护理教育工作者与未参加教育研讨会的护理教育工作者的平均得分存在差异(t=5.2334;术中,0.001)。结论马拉维护理教育工作者在案例教学中具有中等水平的自我效能感。因此,这项研究表明,需要护士教育工作者参与的策略,可以提高他们的自我效能感水平在使用案例研究。
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引用次数: 0
Adequacy of completion of radiology request forms at St. Francis’ Hospital of Katete District: A clinical audit in Zambia 圣弗朗西斯医院凯特区放射申请表的充分填写:赞比亚的临床审计
4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-08-02 DOI: 10.4314/mmj.v35i2.7
Mubanga Bwalya, Osward Bwanga, John. Y. Mvula, Foster Munsanje, Bretina Muntanga
BackgroundMost imaging examinations use ionising radiation which causes biological effects on the body. For this reason, only justified examinations should be requested by adequately completing the radiology request form (RRF) by clinicians. The RRF allows radiographers and radiologists to assess if the benefit outweighs the risk associated with medical radiation exposure. Inadequately or incorrectly filled RRFs leads to unnecessary radiation exposures, imaging errors, and delays in performing the examination. Therefore, this study aimed at auditing the adequacy of completion of general RRFs at St. Francis’ Hospital of Katete District in Zambia.MethodsThis was a quantitative study in which RRFs for general radiography from January to December 2020 were audited. Data were collected retrospectively using a checklist from a total of 974 RRFs. The filled-in forms were assessed for completeness of information related to the patient, examination, and referring clinician. Data were analysed using descriptive statistics. The standard of completeness was based on the Royal College of Radiologists (RCR) guidelines requiring all the designated variables completed on the RRF.ResultsMost N=881(90.5%), RRFs were incompletely filled. With regards to patient’s identification, the findings revealed N=4(0.5%), N=597(61.3%), N=3(0.4%), and N=2(0.3%) RRFs devoid of patient’s name, hospital number, age, and gender, respectively. Regarding the examination, the findings revealed N=3(0.4%), N=68(7%), N=449(46.2%), and N=336 (37%) RRFs devoid of requested examination, indication, clinical history, and level of urgency, respectively. Regarding the referrer, the findings revealed N=135(13.9%), N=173(17.8 %), N=472(48.5%), and N=31(3.2%) RRFs were devoid of information relating to the ward, clinicians’ name, referring department, and signature, respectively.Conclusion This audit reports that most of the RRFs were incompletely filled-in at St. Francis’ Hospital. Furthermore, the hospital number, clinical history and level of urgency were the frequently unfilled variables. Overall, there were gaps in completion of RRFs requiring remedying.
背景:大多数成像检查使用电离辐射,这会对人体产生生物效应。出于这个原因,只有合理的检查应要求充分填写放射科申请表(RRF)由临床医生。RRF允许放射技师和放射科医生评估与医疗辐射照射相关的益处是否超过风险。不充分或不正确填充的rrf会导致不必要的辐射暴露、成像错误和检查延迟。因此,本研究的目的是审计赞比亚凯特区圣弗朗西斯医院完成一般rrf的情况是否充分。方法本研究是一项定量研究,对2020年1月至12月普通x线摄影的rrf进行审计。使用清单从974个RRFs中回顾性收集数据。对填写的表格进行评估,以确定与患者、检查和转诊临床医生相关的信息是否完整。数据分析采用描述性统计。完整性的标准是基于皇家放射学院(RCR)的指导方针,要求在RRF上完成所有指定的变量。结果N=881例(90.5%)患者RRFs填写不全。在患者识别方面,分别有N=4(0.5%)、N=597(61.3%)、N=3(0.4%)和N=2(0.3%)的RRFs没有患者姓名、医院编号、年龄和性别。关于检查结果,分别有N=3(0.4%)、N=68(7%)、N=449(46.2%)和N=336(37%)例RRFs没有要求的检查、适应证、临床病史和紧急程度。关于转诊者,结果显示N=135(13.9%)、N=173(17.8%)、N=472(48.5%)和N=31(3.2%)的rrf分别缺乏与病房、临床医生姓名、转诊部门和签名相关的信息。结论本次审计报告称,圣弗朗西斯医院的大部分rrf未完全填写。此外,医院数量、临床病史和紧急程度是经常未填写的变量。总的来说,在完成区域储备金方面存在需要补救的差距。
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引用次数: 0
Association of menopausal symptoms and menopausal quality of life with premenstrual syndrome 绝经期症状和绝经期生活质量与经前综合征的关系
4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-08-02 DOI: 10.4314/mmj.v35i2.4
Fatma Tuygar- Okutucu, Gamzenur Cimilli- Senocak, Hacer A. Ceyhun, Halil Ozcan
BackgroundPremenstrual symptoms at reproductive age resemble menopausal symptoms and have symptomatic commonalities. We hypothesized that women with previous premenstrual syndrome may be more prone to develop menopausal symptoms and aimed to investigate the association of menopausal symptoms and menopausal quality of life with premenstrual symptoms. MethodsThe study included 120 postmenopausal women. We evaluated the current menopausal symptoms with menopause rating scale (MRS) and quality of life with menopause-specific quality of life scale (MSQoL), previous premenstrual symptoms with premenstrual syndrome scale (PMSS) retrospectively and compared the associations statistically. ResultsAccording to retrospective PMSS, participants were divided into two groups; with and without premenstrual syndrome (PMS). PMS group included 29 (24.2%) participants and 91 (75.8%) participants were in group without PMS. Sociodemographic characteristics of groups were similar. Somatic and psychological symptoms were higher in MRS of PMS group. Evaluating the MSQoL; psychosocial and physical symptoms were impaired in the PMS group. Vasomotor, urogenital and sexual symptoms were similar in both groups. ConclusionPremenstrual and menopausal symptoms were related in terms of somatic, and psychosocial symptoms but not in vasomotor, urogenital, and sexual symptoms. It seems that women with previous premenstrual symptoms are more likely to develop menopausal symptoms in some ways. However, a prospective longitudinal study may be needed for more conclusive results.
育龄期经前症状与绝经期症状相似,具有症状共性。我们假设先前有经前综合征的妇女可能更容易出现绝经期症状,目的是调查绝经期症状和绝经期生活质量与经前症状的关系。方法研究对象为120名绝经后妇女。我们用绝经评定量表(MRS)评估当前绝经期症状,用绝经特异性生活质量量表(MSQoL)评估生活质量,用经前综合征量表(PMSS)评估既往经前症状,并对其相关性进行统计学比较。结果根据回顾性PMSS量表,受试者分为两组;有或没有经前综合症(PMS)经前综合征组29例(24.2%),非经前综合征组91例(75.8%)。各组的社会人口学特征相似。经前症候群患者的躯体和心理症状明显高于经前症候群。评估MSQoL;经前综合症组的心理社会和生理症状受损。两组患者血管舒缩、泌尿生殖和性症状相似。结论经前和绝经期症状与躯体和社会心理症状相关,而与血管舒缩、泌尿生殖和性症状无关。在某些方面,似乎有过经前症状的女性更有可能出现更年期症状。然而,一个前瞻性的纵向研究可能需要更结论性的结果。
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引用次数: 0
Anopheles funestus sensu stricto Giles (Diptera:Culicidae) bites after sunrise at two rural villages in northern Malawi and its implications for malaria vector control 马拉维北部两个乡村日出后蚊虫叮咬(双翅目:库蚊科)及其对疟疾媒介控制的影响
4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-08-02 DOI: 10.4314/mmj.v35i2.2
Themba Mzilahowa, Steven Gowelo, John Chiphwanya, Andrew Bauleni, Mavuto Mukaka
Introduction Malawi has scaled up distribution and use of LLINs but their effectiveness depends on vector behaviour. This study reports information on where and when peak biting takes place by Anopheles vectors at two study sites in northern Malawi. MethodsThe study was carried out at a single village each in Nkhata Bay and Karonga districts, northern Malawi. Monthly, three teams of four people each sampled mosquitoes using Human Landing Collections (HLCs) from 6.00 pm to 6.00 am. Mosquitoes were counted and identified by PCR. Plasmodium falciparum sporozoites were detected by ELISA and an entomological inoculation rate was estimated. ResultsA total of 4,668 and 2,079 mosquitoes were sampled in Nkhata Bay and Karonga districts respectively. An. funestus s.s was common (91.3%; n = 2,611) in Nkhata Bay while An. arabiensis was common (96.9%; n = 706) in Karonga. Pf sporozoite rates varied from 0.8% (4/484) to 3.3% (51/1558). Individuals in Nkhata Bay received more bites (approx. 200 bites/ person/ night) compared to Karonga (approx. 50 bites/ person/ night). An. funestus was more likely to bite indoors (p=0.002) while An. arabiensis was (p=0.05) more likely to bite outdoors. Furthermore, An. funestus peak biting was in the early morning hours from 4:00 am (approx. 331 and 177 bites/ person/ night indoors and outdoors respectively) and remained high till 6:00 am. An. arabiensis peak biting (approx. 63 and 62 bites/ person/ night indoors and outdoors respectively) was around mid-night (12:00). An EIR of 108.4 infective bites/ person/ year was estimated for Nkhata Bay compared to 9.1 infective bites/ person/ year for Karonga.Conclusion An. funestus s.s. had a considerable Pf sporozite infection rate and EIR. The shift in biting behaviour shown by this species poses a challenge to malaria control. Further studies are required to understand the biting behaviour of Anopheles vectors in Malawi.
马拉维扩大了低剂量杀虫剂的分发和使用,但其有效性取决于病媒的行为。本研究报告了马拉维北部两个研究地点按蚊媒介叮咬高峰发生的地点和时间的信息。方法本研究在马拉维北部Nkhata湾和Karonga区各一个村庄进行。每个月,从下午6点至早上6点,使用人类登陆采集(hlc)对三组四人的蚊子进行取样。采用PCR法对蚊虫进行计数和鉴定。采用酶联免疫吸附法检测恶性疟原虫孢子体,并估计昆虫学接种率。结果在Nkhata湾和Karonga区分别捕获蚊虫4668只和2079只。一个。Funestus s.s常见(91.3%);n = 2611)。Arabiensis较为常见(96.9%);n = 706)。Pf孢子率为0.8%(4/484)~ 3.3%(51/1558)。恩卡塔湾的个体被咬的次数较多(约为。200人/人/夜),而卡隆加(大约200人/夜)。50口/人/夜)。一个。家兔在室内更容易咬人(p=0.002);Arabiensis (p=0.05)更倾向于户外咬伤。此外,一个。狐蝠的叮咬高峰出现在凌晨4点(约5点)。在室内和室外分别为331和177只/人/夜),并一直保持到早上6点。一个。Arabiensis峰值咬人(约;室内和室外分别为63和62只/人/夜),在午夜(12:00)左右。Nkhata湾的EIR估计为108.4人/年,而Karonga湾的EIR为9.1人/年。一个结论。真菌孢子虫感染率和EIR均较高。该物种叮咬行为的转变对疟疾控制构成了挑战。需要进一步研究以了解马拉维按蚊媒介的叮咬行为。
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引用次数: 0
Malawi: What are the implications that aspartame is now a “possible carcinogen”? 马拉维:阿斯巴甜现在是一种“可能的致癌物”,这意味着什么?
4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-08-02 DOI: 10.4314/mmj.v35i2.1
Adamson S. Muula
Aspartame is an artificial non-saccharide sweetener 200 times sweeter than sucrose. It is commonly used as a sugar substitute in foods and beverages. Aspartame is a methyl ester of the aspartic acid/phenylalanine dipeptide category. It (aspartame) was approved by the United States Food and Drug Administration (FDA) in 1974. Its approval was revoked in 1980 before being re-instated a year later. It is one of the most studied food additives in the human food supply. Because of its low caloric value, it is often a preferred sweetener when there are concerns of weight gain, an attribute glucose and sucrose do not have (it is an ingredient of many diet drinks and chewing gum), the latter being, among other concerns, obesitogenic and diabetogenic.
阿斯巴甜是一种人造无糖甜味剂,比蔗糖甜200倍。它通常被用作食品和饮料中的糖替代品。阿斯巴甜是天冬氨酸/苯丙氨酸二肽类的甲酯。阿斯巴甜于1974年被美国食品和药物管理局(FDA)批准使用。它的批准在1980年被撤销,一年后才恢复。它是人类食品供应中研究最多的食品添加剂之一。由于它的低热量,当人们担心体重增加时,它通常是首选的甜味剂,而葡萄糖和蔗糖没有这种特性(它是许多无糖饮料和口香糖的成分),后者在其他问题中,会导致肥胖和糖尿病。
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引用次数: 0
Malawi’s LGBTQI controversy 马拉维的lgbti传统
4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-08-02 DOI: 10.4314/mmj.v35i2.10
Thengo Kavinya
Same-sex sexual activity is prohibited in Malawi under the Penal Code, which criminalises acts of ‘carnal knowledge against the order of nature’ as well as ‘gross indecency’; proclaiming a maximum penalty of 14 years imprisonment.
马拉维刑法禁止同性性行为,将“违反自然秩序的肉体知识”和“严重猥亵”行为定为刑事犯罪;宣布最高刑罚为14年监禁。
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引用次数: 0
期刊
Malawi Medical Journal
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