Pub Date : 2026-03-01Epub Date: 2026-03-20DOI: 10.1051/medsci/2026036
Anny Slama Schwok
Approximately 5 % of patients suffer from the sequelae of the COVID-19 pandemics, representing a considerable number of individuals, often young or middle-aged working adults (18-50 years). Among them, women are disproportionately affected. The most common neurological symptoms include persistent cognitive impairment, known as "brain fog", chronic fatigue syndrome, inflammation of the nervous system (motor or autonomous), anxiety and depression, all of which significantly reduce patients' quality of life. There is therefore an urgent societal need to identify appropriate treatments based on a clear understanding of the underlying pathological mechanisms. This review describes the state of the art in Long neuro-COVID, with an emphasis on neuroinflammation, alteration of neurotransmission, and immune, endothelial and microvascular dysfunctions.
{"title":"[Post-COVID neurological sequelae, proposed mechanisms and therapeutic approaches].","authors":"Anny Slama Schwok","doi":"10.1051/medsci/2026036","DOIUrl":"https://doi.org/10.1051/medsci/2026036","url":null,"abstract":"<p><p>Approximately 5 % of patients suffer from the sequelae of the COVID-19 pandemics, representing a considerable number of individuals, often young or middle-aged working adults (18-50 years). Among them, women are disproportionately affected. The most common neurological symptoms include persistent cognitive impairment, known as \"brain fog\", chronic fatigue syndrome, inflammation of the nervous system (motor or autonomous), anxiety and depression, all of which significantly reduce patients' quality of life. There is therefore an urgent societal need to identify appropriate treatments based on a clear understanding of the underlying pathological mechanisms. This review describes the state of the art in Long neuro-COVID, with an emphasis on neuroinflammation, alteration of neurotransmission, and immune, endothelial and microvascular dysfunctions.</p>","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 3","pages":"280-289"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147486528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2026-03-20DOI: 10.1051/medsci/2026039
Laurent Aussel
Since the introduction of ChatGPT in late 2022, academia has undergone a radical transformation in the use of artificial intelligence. While students widely adopted the tool, professors remain concerned about its impact. Initially skeptical, they now face the challenge of reinventing both assessment and teaching strategies in order to embrace these new tools while preserving personalized learning and critical thinking, and while acknowledging their environmental cost. Among researchers, AI has driven spectacular breakthroughs in many fields, especially in biomedical research, yet it still divides the scientific community over concerns about risks of errors and ethical issues.
{"title":"[Researchers, students, and faculty researchers: how AI has transformed their daily lives].","authors":"Laurent Aussel","doi":"10.1051/medsci/2026039","DOIUrl":"https://doi.org/10.1051/medsci/2026039","url":null,"abstract":"<p><p>Since the introduction of ChatGPT in late 2022, academia has undergone a radical transformation in the use of artificial intelligence. While students widely adopted the tool, professors remain concerned about its impact. Initially skeptical, they now face the challenge of reinventing both assessment and teaching strategies in order to embrace these new tools while preserving personalized learning and critical thinking, and while acknowledging their environmental cost. Among researchers, AI has driven spectacular breakthroughs in many fields, especially in biomedical research, yet it still divides the scientific community over concerns about risks of errors and ethical issues.</p>","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 3","pages":"290-294"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147486556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2026-03-20DOI: 10.1051/medsci/2026034
Étienne Ruppé, Philippe Glaser
Antibiotic resistance is a major public health issue, responsible for around one million deaths worldwide each year. It arises in bacteria as a result of mutations or horizontal gene transfer of resistance genes. The environment plays a crucial role in the emergence and spread of these genes, with environmental bacteria acting as reservoirs. Addressing antibiotic resistance therefore requires a multisectoral and multidisciplinary "One Health" approach that spans the human, animal and environmental sectors. To combat antimicrobial resistance, it is essential to reduce the use of antibiotic, improve hygiene conditions, and strengthen surveillance.
{"title":"[Emergence, evolution and spread of antibiotic resistance].","authors":"Étienne Ruppé, Philippe Glaser","doi":"10.1051/medsci/2026034","DOIUrl":"https://doi.org/10.1051/medsci/2026034","url":null,"abstract":"<p><p>Antibiotic resistance is a major public health issue, responsible for around one million deaths worldwide each year. It arises in bacteria as a result of mutations or horizontal gene transfer of resistance genes. The environment plays a crucial role in the emergence and spread of these genes, with environmental bacteria acting as reservoirs. Addressing antibiotic resistance therefore requires a multisectoral and multidisciplinary \"One Health\" approach that spans the human, animal and environmental sectors. To combat antimicrobial resistance, it is essential to reduce the use of antibiotic, improve hygiene conditions, and strengthen surveillance.</p>","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 3","pages":"263-269"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147486466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2026-03-20DOI: 10.1051/medsci/2026023
David Cohen, Melanie Descamps, Charline Grossard, François Vonthron, Jean Xavier
{"title":"[Dyslexia and music rhythm perception: a computer-based training to improve reading speed and accuracy].","authors":"David Cohen, Melanie Descamps, Charline Grossard, François Vonthron, Jean Xavier","doi":"10.1051/medsci/2026023","DOIUrl":"https://doi.org/10.1051/medsci/2026023","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 3","pages":"223-225"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147486477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2026-03-20DOI: 10.1051/medsci/2026041
Bertrand Jordan
Since 2017, the CAR-T ex vivo approach has been very successful for the treatment of B cell malignancies in spite of its complexity and cost. A novel method involves transforming T lymphocytes into CAR-T cells in situ (therefore, in vivo) and promises simplicity, speed and affordability. It also seems applicable to several autoimmune diseases and is currently the object of much activity and interest in academic and corporate environments.
{"title":"[In vivo CAR-Ts, a significant breakthrough].","authors":"Bertrand Jordan","doi":"10.1051/medsci/2026041","DOIUrl":"https://doi.org/10.1051/medsci/2026041","url":null,"abstract":"<p><p>Since 2017, the CAR-T ex vivo approach has been very successful for the treatment of B cell malignancies in spite of its complexity and cost. A novel method involves transforming T lymphocytes into CAR-T cells in situ (therefore, in vivo) and promises simplicity, speed and affordability. It also seems applicable to several autoimmune diseases and is currently the object of much activity and interest in academic and corporate environments.</p>","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 3","pages":"311-314"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147486484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2026-03-20DOI: 10.1051/medsci/2026030
Sylvain Baize, Laura Soyer
{"title":"[Immunosuppression and severe Lassa fever].","authors":"Sylvain Baize, Laura Soyer","doi":"10.1051/medsci/2026030","DOIUrl":"https://doi.org/10.1051/medsci/2026030","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 3","pages":"245-247"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147486403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2026-03-20DOI: 10.1051/medsci/2026028
Betty Gardie, Salam Idriss, David Hoogewijs, Alexandre Marchand, Laurent Martin, Yaël Zermati, François Girodon
{"title":"[Identification of a hepatic-like erythropoietin associated with a novel cause of polycythemia].","authors":"Betty Gardie, Salam Idriss, David Hoogewijs, Alexandre Marchand, Laurent Martin, Yaël Zermati, François Girodon","doi":"10.1051/medsci/2026028","DOIUrl":"https://doi.org/10.1051/medsci/2026028","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 3","pages":"241-244"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147486408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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